Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | vivapain-2 | 0.151 | 0.401 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.038 | 0.0687 | 0.1523 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.151 | 0.401 | 0.4699 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.038 | 0.0687 | 0.0662 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.038 | 0.0687 | 0.1523 |
Onchocerca volvulus | 0.151 | 0.401 | 1 | |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0838 | 0.2034 | 0.5039 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0838 | 0.2034 | 0.2012 |
Toxoplasma gondii | cathepsin CPC1 | 0.038 | 0.0687 | 0.1523 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0838 | 0.2034 | 0.2012 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3546 | 1 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.3546 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.038 | 0.0687 | 0.0805 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0838 | 0.2034 | 0.2012 |
Giardia lamblia | Cathepsin B precursor | 0.1629 | 0.4359 | 1 |
Leishmania major | cathepsin L-like protease | 0.151 | 0.401 | 0.3994 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1052 | 0.2663 | 0.312 |
Echinococcus granulosus | cathepsin L | 0.038 | 0.0687 | 0.0805 |
Entamoeba histolytica | hypothetical protein | 0.038 | 0.0687 | 0.1657 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.038 | 0.0687 | 0.0805 |
Loa Loa (eye worm) | hypothetical protein | 0.3048 | 0.8533 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.151 | 0.401 | 0.9194 |
Loa Loa (eye worm) | hypothetical protein | 0.151 | 0.401 | 0.4699 |
Plasmodium vivax | unspecified product | 0.0838 | 0.2034 | 0.5039 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.151 | 0.401 | 0.9194 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.038 | 0.0687 | 0.1657 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0838 | 0.2034 | 0.5039 |
Entamoeba histolytica | cysteine protease, putative | 0.0838 | 0.2034 | 0.5039 |
Mycobacterium leprae | putative S-adenosyl-L-homocysteine hydrolase SahH | 0.0156 | 0.0027 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.151 | 0.401 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.1629 | 0.4359 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.151 | 0.401 | 0.4699 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0838 | 0.2034 | 0.5039 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.038 | 0.0687 | 0.0805 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.151 | 0.401 | 0.9194 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3546 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin H-like cysteine peptidase | 0.038 | 0.0687 | 0.1523 |
Leishmania major | cathepsin L-like protease | 0.3546 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.038 | 0.0687 | 0.1657 |
Leishmania major | cathepsin L-like protease | 0.151 | 0.401 | 0.3994 |
Plasmodium vivax | vivapain-2 | 0.151 | 0.401 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1052 | 0.2663 | 0.312 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.038 | 0.0687 | 0.1523 |
Entamoeba histolytica | cysteine protease, putative | 0.038 | 0.0687 | 0.1657 |
Loa Loa (eye worm) | hypothetical protein | 0.0458 | 0.0915 | 0.1072 |
Brugia malayi | Cathepsin L-like precursor | 0.151 | 0.401 | 0.4699 |
Schistosoma mansoni | cathepsin s | 0.0458 | 0.0915 | 0.1072 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0838 | 0.2034 | 0.4633 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.151 | 0.401 | 0.3994 |
Loa Loa (eye worm) | hypothetical protein | 0.1052 | 0.2663 | 0.312 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.038 | 0.0687 | 0.1657 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.038 | 0.0687 | 0.1523 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0838 | 0.2034 | 0.2383 |
Loa Loa (eye worm) | adenosylhomocysteinase | 0.0156 | 0.0027 | 0.0032 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.151 | 0.401 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0838 | 0.2034 | 0.2383 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.1052 | 0.2663 | 0.312 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.151 | 0.401 | 0.9194 |
Schistosoma mansoni | subfamily C1A non-peptidase homologue (C01 family) | 0.038 | 0.0687 | 0.0805 |
Brugia malayi | Cathepsin L-like precursor | 0.1052 | 0.2663 | 0.312 |
Loa Loa (eye worm) | cathepsin B | 0.1629 | 0.4359 | 0.5108 |
Entamoeba histolytica | cysteine protease, putative | 0.0838 | 0.2034 | 0.5039 |
Plasmodium vivax | unspecified product | 0.0458 | 0.0915 | 0.2229 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.151 | 0.401 | 0.9194 |
Entamoeba histolytica | cysteine protease, putative | 0.038 | 0.0687 | 0.1657 |
Onchocerca volvulus | 0.151 | 0.401 | 1 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.038 | 0.0687 | 0.0805 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.151 | 0.401 | 0.9194 |
Trypanosoma cruzi | cysteine protease, putative | 0.0838 | 0.2034 | 0.2012 |
Plasmodium falciparum | serine repeat antigen 1 | 0.038 | 0.0687 | 0.1657 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.038 | 0.0687 | 0.1523 |
Loa Loa (eye worm) | hypothetical protein | 0.038 | 0.0687 | 0.0805 |
Echinococcus multilocularis | cathepsin b | 0.3048 | 0.8533 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.151 | 0.401 | 0.4699 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1052 | 0.2663 | 0.6084 |
Plasmodium falciparum | serine repeat antigen 9 | 0.038 | 0.0687 | 0.1657 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0838 | 0.2034 | 0.2383 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3546 | 1 | 1 |
Schistosoma mansoni | adenosylhomocysteinase | 0.0156 | 0.0027 | 0.0032 |
Loa Loa (eye worm) | hypothetical protein | 0.0458 | 0.0915 | 0.1072 |
Loa Loa (eye worm) | hypothetical protein | 0.038 | 0.0687 | 0.0805 |
Entamoeba histolytica | cysteine protease, putative | 0.038 | 0.0687 | 0.1657 |
Brugia malayi | Papain family cysteine protease containing protein | 0.038 | 0.0687 | 0.0805 |
Toxoplasma gondii | cathepsin CPC2 | 0.038 | 0.0687 | 0.1523 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.038 | 0.0687 | 0.1523 |
Loa Loa (eye worm) | hypothetical protein | 0.1052 | 0.2663 | 0.312 |
Loa Loa (eye worm) | hypothetical protein | 0.0659 | 0.1507 | 0.1766 |
Echinococcus granulosus | cathepsin l1 | 0.1052 | 0.2663 | 0.312 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin F-like cysteine peptidase | 0.038 | 0.0687 | 0.1523 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3546 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.151 | 0.401 | 1 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.038 | 0.0687 | 0.1657 |
Brugia malayi | Papain family cysteine protease containing protein | 0.038 | 0.0687 | 0.0805 |
Loa Loa (eye worm) | hypothetical protein | 0.0595 | 0.1318 | 0.1544 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.038 | 0.0687 | 0.1657 |
Onchocerca volvulus | 0.151 | 0.401 | 1 | |
Brugia malayi | cahepsin L-like non-peptiedase homolog | 0.038 | 0.0687 | 0.0805 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.3546 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0458 | 0.0915 | 0.1072 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0838 | 0.2034 | 0.5039 |
Entamoeba histolytica | cysteine protease, putative | 0.0838 | 0.2034 | 0.5039 |
Mycobacterium ulcerans | S-adenosyl-L-homocysteine hydrolase | 0.0156 | 0.0027 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1052 | 0.2663 | 0.6618 |
Loa Loa (eye worm) | fibroinase | 0.151 | 0.401 | 0.4699 |
Onchocerca volvulus | 0.151 | 0.401 | 1 | |
Echinococcus multilocularis | cathepsin L | 0.038 | 0.0687 | 0.0805 |
Plasmodium falciparum | serine repeat antigen 8 | 0.038 | 0.0687 | 0.1657 |
Brugia malayi | Cathepsin L-like precursor | 0.0458 | 0.0915 | 0.1072 |
Plasmodium falciparum | serine repeat antigen 7 | 0.038 | 0.0687 | 0.1657 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.038 | 0.0687 | 0.1657 |
Schistosoma mansoni | cathepsin B (C01 family) | 0.038 | 0.0687 | 0.0805 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.038 | 0.0687 | 0.1657 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.038 | 0.0687 | 0.0805 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1629 | 0.4359 | 0.5108 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.038 | 0.0687 | 0.0805 |
Plasmodium vivax | serine-repeat antigen 3 (SERA) | 0.038 | 0.0687 | 0.1657 |
Echinococcus multilocularis | cathepsin b | 0.3048 | 0.8533 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0838 | 0.2034 | 0.2012 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.3048 | 0.8533 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.151 | 0.401 | 0.9194 |
Leishmania major | cathepsin L-like protease | 0.151 | 0.401 | 0.3994 |
Brugia malayi | Papain family cysteine protease containing protein | 0.151 | 0.401 | 0.4699 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3546 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.151 | 0.401 | 0.9194 |
Entamoeba histolytica | cysteine protease, putative | 0.038 | 0.0687 | 0.1657 |
Onchocerca volvulus | Cathepsin F homolog | 0.151 | 0.401 | 1 |
Plasmodium vivax | serine-repeat antigen 2 (SERA) | 0.038 | 0.0687 | 0.1657 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1629 | 0.4359 | 0.4344 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.3048 | 0.8533 | 0.8529 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0838 | 0.2034 | 0.5039 |
Entamoeba histolytica | cysteine proteinase, putative | 0.151 | 0.401 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.038 | 0.0687 | 0.1657 |
Entamoeba histolytica | cysteine proteinase, putative | 0.151 | 0.401 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3546 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.038 | 0.0687 | 0.0805 |
Toxoplasma gondii | cathepsin B | 0.1629 | 0.4359 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.151 | 0.401 | 0.4699 |
Plasmodium falciparum | dipeptidyl aminopeptidase 3 | 0.038 | 0.0687 | 0.1657 |
Plasmodium vivax | serine-repeat antigen 5 (SERA) | 0.038 | 0.0687 | 0.1657 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase | 0.038 | 0.0687 | 0.1523 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3546 | 1 | 1 |
Loa Loa (eye worm) | cysteine proteinase cathepsin Z | 0.038 | 0.0687 | 0.0805 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3546 | 1 | 1 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.2417 | 0.6677 | 0.6668 |
Brugia malayi | cathepsin L-like cysteine proteinase | 0.038 | 0.0687 | 0.0805 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or H-like cysteine peptidase | 0.038 | 0.0687 | 0.1523 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3546 | 1 | 1 |
Plasmodium vivax | serine-repeat antigen 4 (SERA), putative | 0.038 | 0.0687 | 0.1657 |
Echinococcus multilocularis | sterol O acyltransferase 1 | 0.0659 | 0.1507 | 0.1766 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.038 | 0.0687 | 0.0805 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.038 | 0.0687 | 0.0805 |
Schistosoma mansoni | dipeptidyl-peptidase I (C01 family) | 0.038 | 0.0687 | 0.0805 |
Entamoeba histolytica | cysteine protease, putative | 0.0838 | 0.2034 | 0.5039 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.151 | 0.401 | 0.9194 |
Toxoplasma gondii | preprocathepsin c precursor, putative | 0.038 | 0.0687 | 0.1523 |
Onchocerca volvulus | 0.1052 | 0.2663 | 0.5946 | |
Echinococcus multilocularis | adenosylhomocysteinase | 0.0156 | 0.0027 | 0.0032 |
Onchocerca volvulus | 0.151 | 0.401 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.038 | 0.0687 | 0.1523 |
Plasmodium vivax | dipeptidyl aminopeptidase 3, putative | 0.038 | 0.0687 | 0.1657 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.151 | 0.401 | 0.9194 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.151 | 0.401 | 0.9194 |
Entamoeba histolytica | cysteine protease, putative | 0.0838 | 0.2034 | 0.5039 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.151 | 0.401 | 0.9194 |
Echinococcus granulosus | cathepsin b | 0.3048 | 0.8533 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.151 | 0.401 | 0.4699 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.3048 | 0.8533 | 1 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0458 | 0.0915 | 0.1072 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.038 | 0.0687 | 0.0805 |
Schistosoma mansoni | cathepsin S (C01 family) | 0.038 | 0.0687 | 0.0805 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0458 | 0.0915 | 0.089 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.151 | 0.401 | 0.4699 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3546 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.038 | 0.0687 | 0.0805 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.038 | 0.0687 | 0.0805 |
Entamoeba histolytica | cysteine protease, putative | 0.0838 | 0.2034 | 0.5039 |
Plasmodium vivax | unspecified product | 0.038 | 0.0687 | 0.1657 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.151 | 0.401 | 0.9194 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.038 | 0.0687 | 0.1523 |
Loa Loa (eye worm) | hypothetical protein | 0.1052 | 0.2663 | 0.312 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0458 | 0.0915 | 0.089 |
Loa Loa (eye worm) | cysteine protease | 0.151 | 0.401 | 0.4699 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.151 | 0.401 | 0.9194 |
Brugia malayi | cathepsin L precursor | 0.038 | 0.0687 | 0.0805 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.151 | 0.401 | 0.9194 |
Schistosoma mansoni | cathepsin C | 0.038 | 0.0687 | 0.0805 |
Leishmania major | cathepsin L-like protease | 0.151 | 0.401 | 0.3994 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.038 | 0.0687 | 0.1523 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0838 | 0.2034 | 0.2383 |
Onchocerca volvulus | 0.151 | 0.401 | 1 | |
Plasmodium vivax | dipeptidyl aminopeptidase 2, putative | 0.038 | 0.0687 | 0.1657 |
Entamoeba histolytica | cysteine protease, putative | 0.0838 | 0.2034 | 0.5039 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.151 | 0.401 | 0.4699 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.3048 | 0.8533 | 1 |
Echinococcus multilocularis | cysteine protease | 0.151 | 0.401 | 0.4699 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.151 | 0.401 | 1 |
Echinococcus granulosus | cysteine protease | 0.0838 | 0.2034 | 0.2383 |
Plasmodium falciparum | dipeptidyl aminopeptidase 1 | 0.038 | 0.0687 | 0.1657 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.038 | 0.0687 | 0.1523 |
Entamoeba histolytica | cysteine protease, putative | 0.0838 | 0.2034 | 0.5039 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.151 | 0.401 | 0.9194 |
Brugia malayi | Cathepsin L-like precursor | 0.151 | 0.401 | 0.4699 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.038 | 0.0687 | 0.1523 |
Entamoeba histolytica | cysteine protease, putative | 0.0838 | 0.2034 | 0.5039 |
Echinococcus multilocularis | cysteine protease | 0.151 | 0.401 | 0.4699 |
Brugia malayi | Cathepsin L-like precursor | 0.151 | 0.401 | 0.4699 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.151 | 0.401 | 0.4699 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.151 | 0.401 | 0.9194 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0458 | 0.0915 | 0.1072 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.151 | 0.401 | 1 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0838 | 0.2034 | 0.2383 |
Brugia malayi | Cathepsin L-like precursor | 0.151 | 0.401 | 0.4699 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.151 | 0.401 | 0.9194 |
Echinococcus granulosus | cathepsin b | 0.3048 | 0.8533 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.151 | 0.401 | 0.4699 |
Entamoeba histolytica | cysteine protease, putative | 0.0838 | 0.2034 | 0.5039 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0838 | 0.2034 | 0.5039 |
Leishmania major | cathepsin L-like protease | 0.151 | 0.401 | 0.3994 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.151 | 0.401 | 0.4699 |
Giardia lamblia | Cathepsin B precursor | 0.1629 | 0.4359 | 1 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.1629 | 0.4359 | 0.4344 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.151 | 0.401 | 0.9194 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.151 | 0.401 | 0.9194 |
Plasmodium vivax | serine-repeat antigen 4 (SERA) | 0.038 | 0.0687 | 0.1657 |
Entamoeba histolytica | cysteine protease, putative | 0.0838 | 0.2034 | 0.5039 |
Trichomonas vaginalis | conserved hypothetical protein | 0.038 | 0.0687 | 0.1523 |
Entamoeba histolytica | cysteine protease, putative | 0.0838 | 0.2034 | 0.5039 |
Brugia malayi | fibroinase precursor | 0.038 | 0.0687 | 0.0805 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3546 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.3048 | 0.8533 | 1 |
Echinococcus multilocularis | cathepsin L | 0.0838 | 0.2034 | 0.2383 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.3546 | 1 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.151 | 0.401 | 0.3994 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.1629 | 0.4359 | 0.4344 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1052 | 0.2663 | 0.6084 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.3048 | 0.8533 | 1 |
Plasmodium falciparum | serine repeat antigen 3 | 0.038 | 0.0687 | 0.1657 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.038 | 0.0687 | 0.0805 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.151 | 0.401 | 0.9194 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.151 | 0.401 | 0.9194 |
Echinococcus granulosus | sterol O acyltransferase 1 | 0.0659 | 0.1507 | 0.1766 |
Loa Loa (eye worm) | hypothetical protein | 0.038 | 0.0687 | 0.0805 |
Loa Loa (eye worm) | hypothetical protein | 0.038 | 0.0687 | 0.0805 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.038 | 0.0687 | 0.1523 |
Plasmodium falciparum | dipeptidyl aminopeptidase 2 | 0.038 | 0.0687 | 0.1657 |
Entamoeba histolytica | cysteine protease, putative | 0.0838 | 0.2034 | 0.5039 |
Leishmania major | cathepsin L-like protease | 0.3546 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.151 | 0.401 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.038 | 0.0687 | 0.1523 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.151 | 0.401 | 0.9194 |
Plasmodium falciparum | serine repeat antigen 6 | 0.038 | 0.0687 | 0.1657 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.3546 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.3088 | 0.8653 | 0.8649 |
Plasmodium vivax | dipeptidyl aminopeptidase 1, putative | 0.038 | 0.0687 | 0.1657 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0838 | 0.2034 | 0.2012 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0458 | 0.0915 | 0.1072 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0838 | 0.2034 | 0.2383 |
Trichomonas vaginalis | conserved hypothetical protein | 0.038 | 0.0687 | 0.1523 |
Plasmodium falciparum | serine repeat antigen 4 | 0.038 | 0.0687 | 0.1657 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.151 | 0.401 | 0.9194 |
Schistosoma mansoni | sterol O-acyltransferase 1 | 0.0659 | 0.1507 | 0.1766 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0838 | 0.2034 | 0.2012 |
Giardia lamblia | Cathepsin B precursor | 0.1629 | 0.4359 | 1 |
Mycobacterium tuberculosis | Probable adenosylhomocysteinase SahH (S-adenosyl-L-homocysteine hydrolase) (adohcyase) | 0.0156 | 0.0027 | 0.5 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.151 | 0.401 | 0.4699 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0838 | 0.2034 | 0.4633 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0838 | 0.2034 | 0.5039 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.151 | 0.401 | 0.4699 |
Plasmodium falciparum | serine repeat antigen 5 | 0.038 | 0.0687 | 0.1657 |
Echinococcus granulosus | cathepsin L | 0.0838 | 0.2034 | 0.2383 |
Plasmodium vivax | vivapain-3 | 0.0838 | 0.2034 | 0.5039 |
Plasmodium falciparum | serine repeat antigen 2 | 0.038 | 0.0687 | 0.1657 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.151 | 0.401 | 0.9194 |
Loa Loa (eye worm) | hypothetical protein | 0.038 | 0.0687 | 0.0805 |
Brugia malayi | cathepsin L-like precursor | 0.1052 | 0.2663 | 0.312 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.151 | 0.401 | 0.4699 |
Brugia malayi | Cathepsin L-like precursor | 0.151 | 0.401 | 0.4699 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.151 | 0.401 | 0.9194 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.038 | 0.0687 | 0.0805 |
Onchocerca volvulus | 0.151 | 0.401 | 1 | |
Echinococcus granulosus | adenosylhomocysteinase | 0.0156 | 0.0027 | 0.0032 |
Brugia malayi | Adenosylhomocysteinase | 0.0156 | 0.0027 | 0.0032 |
Plasmodium vivax | vivapain-1 | 0.0838 | 0.2034 | 0.5039 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | > 100 uM | Inhibition of recombinant human S-adenosyl-L-homocysteine hydrolase assessed as hydrolysis of AdoHcy after 8 mins by HPLC analysis | ChEMBL. | 26037610 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.