Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | glyceraldehyde 3-phosphate dehydrogenase | 0.1286 | 0.3267 | 0.2811 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0826 | 0.1904 | 0.356 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Echinococcus granulosus | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit type | 0.0397 | 0.0634 | 0.1186 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.0826 | 0.1904 | 0.356 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.0826 | 0.1904 | 0.356 |
Plasmodium vivax | tryptophan-rich antigen (Pv-fam-a) | 0.1827 | 0.4867 | 0.9012 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0397 | 0.0634 | 0.1186 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0826 | 0.1904 | 0.1768 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Leishmania major | glyceraldehyde-3-phosphate dehydrogenase-like protein | 0.1847 | 0.4926 | 0.921 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.1286 | 0.3267 | 0.6108 |
Loa Loa (eye worm) | ACC-1 protein | 0.0826 | 0.1904 | 0.1355 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Plasmodium vivax | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.199 | 0.5348 | 1 |
Trypanosoma cruzi | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.1847 | 0.4926 | 0.921 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1286 | 0.3267 | 0.4531 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.0826 | 0.1904 | 0.1768 |
Toxoplasma gondii | glyceraldehyde-3-phosphate dehydrogenase GAPDH2 | 0.199 | 0.5348 | 1 |
Echinococcus multilocularis | gamma aminobutyric acid receptor subunit | 0.0397 | 0.0634 | 0.1186 |
Loa Loa (eye worm) | ACC-1 protein | 0.0826 | 0.1904 | 0.1355 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0429 | 0.0731 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Echinococcus granulosus | nAChR subunit | 0.0429 | 0.0731 | 0.1366 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Brugia malayi | glyceraldehyde 3-phosphate dehydrogenase | 0.0632 | 0.1331 | 0.097 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.2823 | 0.7814 | 1 |
Leishmania major | acetyl-CoA carboxylase, putative | 0.0478 | 0.0876 | 0.1638 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | LGC-31 protein | 0.0826 | 0.1904 | 0.1355 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.0826 | 0.1904 | 0.1768 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0826 | 0.1904 | 0.356 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.0623 | 0.1303 | 0.933 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0826 | 0.1904 | 0.356 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative | 0.0632 | 0.1331 | 0.2489 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0826 | 0.1904 | 0.1768 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | glyceraldehyde-3-phosphate dehydrogenase | 0.1358 | 0.3478 | 0.3036 |
Schistosoma mansoni | acetyl-CoA carboxylase | 0.0478 | 0.0876 | 0.1638 |
Echinococcus multilocularis | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | GABA receptor subunit | 0.0429 | 0.0731 | 0.0103 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Echinococcus granulosus | gamma aminobutyric acid receptor subunit | 0.0397 | 0.0634 | 0.1186 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0826 | 0.1904 | 0.1355 |
Onchocerca volvulus | 0.0429 | 0.0731 | 0.0758 | |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.0826 | 0.1904 | 0.356 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.0826 | 0.1904 | 0.1768 |
Brugia malayi | Glyceraldehyde 3-phosphate dehydrogenase | 0.199 | 0.5348 | 0.6565 |
Onchocerca volvulus | 0.0429 | 0.0731 | 0.0758 | |
Brugia malayi | Cation transporter family protein | 0.0826 | 0.1904 | 0.1768 |
Toxoplasma gondii | acetyl-CoA carboxylase ACC1 | 0.0478 | 0.0876 | 0.1638 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0826 | 0.1904 | 0.356 |
Toxoplasma gondii | acetyl-coA carboxylase ACC2 | 0.0478 | 0.0876 | 0.1638 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.0826 | 0.1904 | 0.1768 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0826 | 0.1904 | 0.356 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0429 | 0.0731 | 0.0134 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0632 | 0.1331 | 0.2489 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0826 | 0.1904 | 0.356 |
Trypanosoma cruzi | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.1847 | 0.4926 | 0.921 |
Wolbachia endosymbiont of Brugia malayi | glyceraldehyde-3-phosphate dehydrogenase, GapA | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0826 | 0.1904 | 0.1768 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0632 | 0.1331 | 0.2489 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.199 | 0.5348 | 1 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0429 | 0.0731 | 0.1366 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.0826 | 0.1904 | 0.1768 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1286 | 0.3267 | 0.2811 |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Leishmania major | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.199 | 0.5348 | 1 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Onchocerca volvulus | Putative nachr subunit | 0.0826 | 0.1904 | 1 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.0826 | 0.1904 | 0.1355 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0826 | 0.1904 | 0.356 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0826 | 0.1904 | 0.356 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.199 | 0.5348 | 1 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0826 | 0.1904 | 0.356 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0826 | 0.1904 | 0.1768 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0397 | 0.0634 | 0.1186 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.0826 | 0.1904 | 0.356 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0429 | 0.0731 | 0.0134 |
Schistosoma mansoni | acetylcholine receptor subunit beta | 0.0397 | 0.0634 | 0.1186 |
Trypanosoma brucei | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.1847 | 0.4926 | 0.921 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative | 0.0632 | 0.1331 | 0.2489 |
Chlamydia trachomatis | glyceraldehyde-3-phosphate dehydrogenase | 0.199 | 0.5348 | 0.5 |
Schistosoma mansoni | nicotinic acetylcholine receptor alpha | 0.0429 | 0.0731 | 0.1366 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0826 | 0.1904 | 0.356 |
Trypanosoma brucei | acetyl-CoA carboxylase | 0.0478 | 0.0876 | 0.1638 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.0826 | 0.1904 | 0.1355 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.067 | 0.1443 | 0.2698 |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.199 | 0.5348 | 1 |
Brugia malayi | Carboxyl transferase domain containing protein | 0.0461 | 0.0826 | 0.0267 |
Giardia lamblia | Glyceraldehyde 3-phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Toxoplasma gondii | glyceraldehyde-3-phosphate dehydrogenase GAPDH1 | 0.199 | 0.5348 | 1 |
Brugia malayi | glutamate-gated chloride channel alpha3A subunit, putative | 0.0429 | 0.0731 | 0.0134 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.1286 | 0.3267 | 0.6108 |
Echinococcus granulosus | acetyl coenzyme A carboxylase 1 | 0.0478 | 0.0876 | 0.1638 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.0826 | 0.1904 | 0.356 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | carboxyl transferase domain-containing protein | 0.0461 | 0.0826 | 0.0205 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.0826 | 0.1904 | 0.1355 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Trypanosoma cruzi | acetyl-CoA carboxylase | 0.0296 | 0.0337 | 0.063 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.199 | 0.5348 | 1 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0826 | 0.1904 | 0.356 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, cytosolic | 0.199 | 0.5348 | 1 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1286 | 0.3267 | 0.4531 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0397 | 0.0634 | 0.1186 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0429 | 0.0731 | 0.1366 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.067 | 0.1443 | 0.2698 |
Schistosoma mansoni | acetylcholine receptor-related | 0.0397 | 0.0634 | 0.1186 |
Mycobacterium leprae | Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) | 0.0654 | 0.1397 | 1 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Treponema pallidum | glyceraldehyde 3-phosphate dehydrogenase (gap) | 0.199 | 0.5348 | 0.5 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Schistosoma mansoni | nAChR subunit | 0.0397 | 0.0634 | 0.1186 |
Schistosoma mansoni | nAChR subunit | 0.0397 | 0.0634 | 0.1186 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0826 | 0.1904 | 0.1355 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Mycobacterium tuberculosis | Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) | 0.0654 | 0.1397 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Brugia malayi | Cation transporter family protein | 0.0826 | 0.1904 | 0.1768 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Brugia malayi | Cation transporter family protein | 0.0826 | 0.1904 | 0.1768 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.199 | 0.5348 | 1 |
Echinococcus multilocularis | nAChR subunit | 0.0429 | 0.0731 | 0.1366 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Echinococcus multilocularis | acetyl coenzyme A carboxylase 1 | 0.0478 | 0.0876 | 0.1638 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0397 | 0.0634 | 0.1186 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | glyceraldehyde-3-phosphate dehydrogenase | 0.1358 | 0.3478 | 0.3036 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Mycobacterium ulcerans | glyceraldehyde 3-phosphate dehydrogenase Gap | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2427 | 0.6641 | 0.6413 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Brugia malayi | Glyceraldehyde 3-phosphate dehydrogenase | 0.0703 | 0.1542 | 0.1265 |
Loa Loa (eye worm) | glyceraldehyde 3-phosphate dehydrogenase | 0.1286 | 0.3267 | 0.2811 |
Plasmodium falciparum | glyceraldehyde-3-phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.199 | 0.5348 | 1 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0826 | 0.1904 | 0.356 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0826 | 0.1904 | 0.356 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2823 | 0.7814 | 0.7666 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0826 | 0.1904 | 0.356 |
Leishmania major | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.0826 | 0.1904 | 0.1355 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0632 | 0.1331 | 0.2489 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0826 | 0.1904 | 0.356 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | < 10 % | The ability of the compound to inhibit platelet aggregation was tested; <10 | ChEMBL. | 3373489 |
Reduction (functional) | = -25 % | Hypolipidemic activity of the compound was expressed as percent decrease in triglycerides in Sprague-Dawley rats | ChEMBL. | 3373489 |
Reduction (functional) | = -4 % | Hypolipidemic activity of the compound was expressed as percent decrease in serum cholesterol in Sprague-Dawley rats | ChEMBL. | 3373489 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.