Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Wolbachia endosymbiont of Brugia malayi | glyceraldehyde-3-phosphate dehydrogenase, GapA | 0.199 | 0.5348 | 1 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0429 | 0.0731 | 0.1366 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.199 | 0.5348 | 1 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0632 | 0.1331 | 0.2489 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0429 | 0.0731 | 0.0134 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0826 | 0.1904 | 0.356 |
Trypanosoma cruzi | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.1847 | 0.4926 | 0.921 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0826 | 0.1904 | 0.356 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0632 | 0.1331 | 0.2489 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.0826 | 0.1904 | 0.356 |
Onchocerca volvulus | 0.0429 | 0.0731 | 0.0758 | |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0826 | 0.1904 | 0.1355 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.0826 | 0.1904 | 0.1768 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0826 | 0.1904 | 0.356 |
Toxoplasma gondii | acetyl-coA carboxylase ACC2 | 0.0478 | 0.0876 | 0.1638 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0826 | 0.1904 | 0.356 |
Toxoplasma gondii | acetyl-CoA carboxylase ACC1 | 0.0478 | 0.0876 | 0.1638 |
Brugia malayi | Cation transporter family protein | 0.0826 | 0.1904 | 0.1768 |
Onchocerca volvulus | 0.0429 | 0.0731 | 0.0758 | |
Brugia malayi | Glyceraldehyde 3-phosphate dehydrogenase | 0.199 | 0.5348 | 0.6565 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | glyceraldehyde-3-phosphate dehydrogenase | 0.1358 | 0.3478 | 0.3036 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0826 | 0.1904 | 0.356 |
Echinococcus granulosus | gamma aminobutyric acid receptor subunit | 0.0397 | 0.0634 | 0.1186 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | GABA receptor subunit | 0.0429 | 0.0731 | 0.0103 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Echinococcus multilocularis | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Schistosoma mansoni | acetyl-CoA carboxylase | 0.0478 | 0.0876 | 0.1638 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.0623 | 0.1303 | 0.933 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0826 | 0.1904 | 0.356 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | LGC-31 protein | 0.0826 | 0.1904 | 0.1355 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0826 | 0.1904 | 0.1768 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative | 0.0632 | 0.1331 | 0.2489 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0826 | 0.1904 | 0.356 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0429 | 0.0731 | 0.0134 |
Loa Loa (eye worm) | ACC-1 protein | 0.0826 | 0.1904 | 0.1355 |
Echinococcus multilocularis | gamma aminobutyric acid receptor subunit | 0.0397 | 0.0634 | 0.1186 |
Toxoplasma gondii | glyceraldehyde-3-phosphate dehydrogenase GAPDH2 | 0.199 | 0.5348 | 1 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1286 | 0.3267 | 0.4531 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.0826 | 0.1904 | 0.1768 |
Trypanosoma cruzi | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.1847 | 0.4926 | 0.921 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.199 | 0.5348 | 1 |
Leishmania major | acetyl-CoA carboxylase, putative | 0.0478 | 0.0876 | 0.1638 |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.2823 | 0.7814 | 1 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Brugia malayi | glyceraldehyde 3-phosphate dehydrogenase | 0.0632 | 0.1331 | 0.097 |
Echinococcus granulosus | nAChR subunit | 0.0429 | 0.0731 | 0.1366 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Leishmania major | glyceraldehyde-3-phosphate dehydrogenase-like protein | 0.1847 | 0.4926 | 0.921 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Plasmodium vivax | tryptophan-rich antigen (Pv-fam-a) | 0.1827 | 0.4867 | 0.9012 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0397 | 0.0634 | 0.1186 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.0826 | 0.1904 | 0.356 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.0826 | 0.1904 | 0.356 |
Plasmodium vivax | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | ACC-1 protein | 0.0826 | 0.1904 | 0.1355 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.1286 | 0.3267 | 0.6108 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit type | 0.0397 | 0.0634 | 0.1186 |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Echinococcus granulosus | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | glyceraldehyde 3-phosphate dehydrogenase | 0.1286 | 0.3267 | 0.2811 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0826 | 0.1904 | 0.356 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0632 | 0.1331 | 0.2489 |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.0826 | 0.1904 | 0.1355 |
Leishmania major | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.199 | 0.5348 | 1 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0826 | 0.1904 | 0.356 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0826 | 0.1904 | 0.356 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0826 | 0.1904 | 0.356 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Plasmodium falciparum | glyceraldehyde-3-phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | hypothetical protein | 0.2823 | 0.7814 | 0.7666 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.199 | 0.5348 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | glyceraldehyde-3-phosphate dehydrogenase | 0.1358 | 0.3478 | 0.3036 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0397 | 0.0634 | 0.1186 |
Echinococcus multilocularis | acetyl coenzyme A carboxylase 1 | 0.0478 | 0.0876 | 0.1638 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Echinococcus multilocularis | nAChR subunit | 0.0429 | 0.0731 | 0.1366 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.199 | 0.5348 | 1 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Brugia malayi | Cation transporter family protein | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | glyceraldehyde 3-phosphate dehydrogenase | 0.1286 | 0.3267 | 0.2811 |
Brugia malayi | Glyceraldehyde 3-phosphate dehydrogenase | 0.0703 | 0.1542 | 0.1265 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Loa Loa (eye worm) | hypothetical protein | 0.2427 | 0.6641 | 0.6413 |
Mycobacterium ulcerans | glyceraldehyde 3-phosphate dehydrogenase Gap | 0.199 | 0.5348 | 1 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Mycobacterium leprae | Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) | 0.0654 | 0.1397 | 1 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.067 | 0.1443 | 0.2698 |
Schistosoma mansoni | acetylcholine receptor-related | 0.0397 | 0.0634 | 0.1186 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Brugia malayi | Cation transporter family protein | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Mycobacterium tuberculosis | Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) | 0.0654 | 0.1397 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0826 | 0.1904 | 0.1355 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Schistosoma mansoni | nAChR subunit | 0.0397 | 0.0634 | 0.1186 |
Treponema pallidum | glyceraldehyde 3-phosphate dehydrogenase (gap) | 0.199 | 0.5348 | 0.5 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Schistosoma mansoni | nAChR subunit | 0.0397 | 0.0634 | 0.1186 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0397 | 0.0634 | 0.1186 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1286 | 0.3267 | 0.4531 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0826 | 0.1904 | 0.356 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, cytosolic | 0.199 | 0.5348 | 1 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.199 | 0.5348 | 1 |
Trypanosoma cruzi | acetyl-CoA carboxylase | 0.0296 | 0.0337 | 0.063 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0429 | 0.0731 | 0.1366 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Giardia lamblia | Glyceraldehyde 3-phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Brugia malayi | Carboxyl transferase domain containing protein | 0.0461 | 0.0826 | 0.0267 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.199 | 0.5348 | 1 |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.0826 | 0.1904 | 0.1355 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.067 | 0.1443 | 0.2698 |
Trypanosoma brucei | acetyl-CoA carboxylase | 0.0478 | 0.0876 | 0.1638 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.0826 | 0.1904 | 0.1355 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | carboxyl transferase domain-containing protein | 0.0461 | 0.0826 | 0.0205 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.0826 | 0.1904 | 0.356 |
Brugia malayi | glutamate-gated chloride channel alpha3A subunit, putative | 0.0429 | 0.0731 | 0.0134 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.1286 | 0.3267 | 0.6108 |
Echinococcus granulosus | acetyl coenzyme A carboxylase 1 | 0.0478 | 0.0876 | 0.1638 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Toxoplasma gondii | glyceraldehyde-3-phosphate dehydrogenase GAPDH1 | 0.199 | 0.5348 | 1 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.0826 | 0.1904 | 0.356 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0397 | 0.0634 | 0.1186 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0826 | 0.1904 | 0.1768 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0826 | 0.1904 | 0.356 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.199 | 0.5348 | 1 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0826 | 0.1904 | 0.356 |
Chlamydia trachomatis | glyceraldehyde-3-phosphate dehydrogenase | 0.199 | 0.5348 | 0.5 |
Schistosoma mansoni | nicotinic acetylcholine receptor alpha | 0.0429 | 0.0731 | 0.1366 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0826 | 0.1904 | 0.356 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative | 0.0632 | 0.1331 | 0.2489 |
Trypanosoma brucei | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.1847 | 0.4926 | 0.921 |
Schistosoma mansoni | acetylcholine receptor subunit beta | 0.0397 | 0.0634 | 0.1186 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0429 | 0.0731 | 0.0134 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Leishmania major | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | hypothetical protein | 0.1286 | 0.3267 | 0.2811 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.0826 | 0.1904 | 0.1355 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0826 | 0.1904 | 0.356 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Onchocerca volvulus | Putative nachr subunit | 0.0826 | 0.1904 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | >= 10 % | Inhibition of collagen-induced platelet aggregation in male SD rats; Inhibition >= 10% but < aspirin (34-96%). | ChEMBL. | 3373489 |
Reduction (functional) | = 23 % | Hypolipidemic activity of the compound was expressed as percent decrease in serum cholesterol in Sprague-Dawley rats | ChEMBL. | 3373489 |
Reduction (functional) | = 35 % | Hypolipidemic activity of the compound was expressed as percent decrease in triglycerides in Sprague-Dawley rats | ChEMBL. | 3373489 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.