Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | adenosine deaminase | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0161 | 0.7625 | 0.8179 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0104 | 0.2877 | 0.5 |
Plasmodium falciparum | adenosine deaminase | 0.0104 | 0.2877 | 0.5 |
Mycobacterium leprae | Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) | 0.0104 | 0.2877 | 0.5 |
Brugia malayi | calpain family protein 1 | 0.0182 | 0.9322 | 1 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0069 | 0 | 0.5 |
Trypanosoma brucei | calpain-like protein, putative | 0.0069 | 0 | 0.5 |
Echinococcus multilocularis | calpain A | 0.019 | 1 | 1 |
Mycobacterium ulcerans | adenosine deaminase | 0.0104 | 0.2877 | 0.5 |
Trypanosoma brucei | calpain-like cysteine peptidase, putative | 0.0069 | 0 | 0.5 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.019 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.01 | 0.0108 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.019 | 1 | 1 |
Trypanosoma brucei | antigen, putative | 0.0069 | 0 | 0.5 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0182 | 0.9322 | 0.9322 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0104 | 0.2877 | 0.5 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0104 | 0.2877 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0134 | 0.5373 | 0.5764 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.01 | 0.0108 |
Trypanosoma brucei | calpain-like protein, putative | 0.0069 | 0 | 0.5 |
Trypanosoma cruzi | calpain cysteine peptidase, putative | 0.0069 | 0 | 0.5 |
Echinococcus multilocularis | calpain family protein 1, d | 0.0134 | 0.5373 | 0.5373 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0104 | 0.2877 | 0.5 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0104 | 0.2877 | 0.5 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0182 | 0.9322 | 1 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0069 | 0 | 0.5 |
Plasmodium vivax | adenosine deaminase, putative | 0.0104 | 0.2877 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.01 | 0.0108 |
Brugia malayi | Adenosine/AMP deaminase family protein | 0.0104 | 0.2877 | 0.3086 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0069 | 0 | 0.5 |
Leishmania major | adenine aminohydrolase | 0.0104 | 0.2877 | 1 |
Onchocerca volvulus | 0.0113 | 0.3676 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.2877 | 0.3086 |
Treponema pallidum | adenosine deaminase | 0.0104 | 0.2877 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0069 | 0 | 0.5 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0069 | 0 | 0.5 |
Schistosoma mansoni | adenosine deaminase-related | 0.0104 | 0.2877 | 0.2877 |
Schistosoma mansoni | adenosine deaminase | 0.0104 | 0.2877 | 0.2877 |
Echinococcus multilocularis | adenosine deaminase | 0.0104 | 0.2877 | 0.2877 |
Mycobacterium tuberculosis | Probable adenosine deaminase Add (adenosine aminohydrolase) | 0.0104 | 0.2877 | 0.5 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0069 | 0 | 0.5 |
Trypanosoma brucei | calpain-like protein, putative | 0.0069 | 0 | 0.5 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0069 | 0 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C2, putative | 0.0069 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.3676 | 0.3943 |
Echinococcus granulosus | family C2 unassigned peptidase C02 family | 0.019 | 1 | 1 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0069 | 0 | 0.5 |
Echinococcus multilocularis | family C2 unassigned peptidase (C02 family) | 0.019 | 1 | 1 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0134 | 0.5373 | 0.5764 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0104 | 0.2877 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.01 | 0.0108 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 0.9322 | 1 |
Trypanosoma brucei | calpain-like protein, putative | 0.0069 | 0 | 0.5 |
Brugia malayi | calpain family protein 1 | 0.0182 | 0.9322 | 1 |
Echinococcus granulosus | adenosine deaminase | 0.0104 | 0.2877 | 0.2877 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0069 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.