Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | musashi | 0.0026 | 0.0146 | 0.0428 |
Schistosoma mansoni | thyroid hormone receptor | 0.0241 | 0.3408 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.0682 | 0.2173 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0037 | 0.0306 | 0.0306 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0099 | 0.1242 | 0.1242 |
Schistosoma mansoni | jun-related protein | 0.0157 | 0.213 | 0.6251 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0099 | 0.1242 | 0.3959 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0047 | 0.0451 | 0.1324 |
Echinococcus multilocularis | jun protein | 0.0193 | 0.268 | 0.7865 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0296 | 0.0296 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.0146 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.1242 | 0.1242 |
Schistosoma mansoni | matrix metallopeptidase-7 (M10 family) | 0.0053 | 0.0544 | 0.1597 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0021 | 0.0068 | 0.0168 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0052 | 0.0536 | 0.1573 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0038 | 0.0327 | 0.096 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0327 | 0.096 |
Onchocerca volvulus | Matrilysin homolog | 0.0117 | 0.1518 | 0.2048 |
Schistosoma mansoni | ap endonuclease | 0.0021 | 0.0068 | 0.02 |
Brugia malayi | Matrixin family protein | 0.0053 | 0.0544 | 0.0544 |
Brugia malayi | nuclear receptor NHR-67 | 0.0047 | 0.0451 | 0.0451 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0099 | 0.1242 | 0.3646 |
Onchocerca volvulus | 0.0026 | 0.0146 | 0.0026 | |
Echinococcus multilocularis | FTZ F1 alpha | 0.0099 | 0.1242 | 0.3646 |
Loa Loa (eye worm) | matrixin family protein | 0.0117 | 0.1518 | 0.1518 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0099 | 0.1242 | 0.1242 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0096 | 0.1208 | 0.385 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0052 | 0.0536 | 0.1573 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0145 | 0.1949 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0099 | 0.1242 | 0.3959 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.0128 | 0.0128 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.0128 | 0.0128 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0031 | 0.0031 |
Schistosoma mansoni | hormone-sensitive lipase (S09 family) | 0.0223 | 0.3138 | 0.9209 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0096 | 0.1208 | 0.3546 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0021 | 0.0068 | 0.0068 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0025 | 0.0128 | 0.0566 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0552 | 0.0552 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0021 | 0.0068 | 0.5 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0025 | 0.0128 | 0.0321 |
Brugia malayi | hypothetical protein | 0.0052 | 0.0536 | 0.0536 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0047 | 0.0451 | 0.0451 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0451 | 0.0451 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0021 | 0.0068 | 1 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0021 | 0.0068 | 0.5 |
Onchocerca volvulus | 0.0152 | 0.205 | 0.2831 | |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.1242 | 0.1242 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0046 | 0.0449 | 0.1316 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.2211 | 0.2211 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.1242 | 0.1242 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0052 | 0.0536 | 0.0536 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0047 | 0.0451 | 0.1324 |
Echinococcus multilocularis | dual specificity | 0.0087 | 0.1065 | 0.3126 |
Schistosoma mansoni | intermediate filament proteins | 0.0026 | 0.0146 | 0.0428 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0099 | 0.1242 | 0.1242 |
Schistosoma mansoni | lozenge | 0.0059 | 0.0644 | 0.189 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.0146 | 0.0465 |
Onchocerca volvulus | 0.0053 | 0.0544 | 0.0613 | |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0536 | 0.0536 |
Entamoeba histolytica | hypothetical protein | 0.0087 | 0.1065 | 0.5302 |
Brugia malayi | hypothetical protein | 0.0052 | 0.0536 | 0.0536 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0138 | 0.0138 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0451 | 0.0451 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0038 | 0.0327 | 0.1042 |
Brugia malayi | Hemopexin family protein | 0.0075 | 0.0878 | 0.0878 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0021 | 0.0068 | 0.0068 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription factor | 0.0193 | 0.268 | 0.854 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0145 | 0.1949 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.1058 | 0.1058 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0099 | 0.1242 | 0.1242 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0099 | 0.1242 | 0.1242 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0053 | 0.0552 | 0.0552 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0682 | 0.2001 |
Brugia malayi | Matrixin family protein | 0.0053 | 0.0544 | 0.0544 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0047 | 0.0451 | 0.0451 |
Loa Loa (eye worm) | glutamate receptor | 0.0041 | 0.0364 | 0.0364 |
Mycobacterium ulcerans | hydrolase | 0.0064 | 0.0719 | 0.3152 |
Brugia malayi | nuclear receptor RXR | 0.0047 | 0.0451 | 0.0451 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0241 | 0.3408 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0099 | 0.1242 | 0.3646 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0047 | 0.0451 | 0.1438 |
Echinococcus multilocularis | metabotropic glutamate receptor 2 | 0.0034 | 0.0263 | 0.0773 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.1242 | 0.1242 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0099 | 0.1242 | 0.1242 |
Entamoeba histolytica | protein kinase, putative | 0.0087 | 0.1065 | 0.5302 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0099 | 0.1242 | 0.1242 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0451 | 0.0451 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0047 | 0.0451 | 0.0475 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0099 | 0.1242 | 0.1242 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0099 | 0.1242 | 0.1242 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0047 | 0.0451 | 0.1324 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0096 | 0.1208 | 0.3546 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.0128 | 0.0321 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0087 | 0.1065 | 0.5302 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0021 | 0.0068 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0451 | 0.0451 |
Echinococcus multilocularis | lamin | 0.0026 | 0.0146 | 0.0428 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0047 | 0.0451 | 0.1324 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.0146 | 0.0465 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.0296 | 0.0296 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0128 | 0.0128 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0099 | 0.1242 | 0.1242 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0047 | 0.0451 | 0.0451 |
Brugia malayi | bZIP transcription factor family protein | 0.0193 | 0.268 | 0.268 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.1242 | 0.1242 |
Schistosoma mansoni | hypothetical protein | 0.0143 | 0.191 | 0.5605 |
Brugia malayi | Matrixin family protein | 0.0053 | 0.0544 | 0.0544 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0099 | 0.1242 | 0.1242 |
Echinococcus multilocularis | hormone sensitive lipase | 0.0223 | 0.3138 | 0.9209 |
Trypanosoma brucei | CMGC/DYRK protein kinase, putative | 0.0087 | 0.1065 | 0.5302 |
Schistosoma mansoni | d-amino acid oxidase | 0.0162 | 0.2211 | 0.6488 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0034 | 0.0263 | 0.0773 |
Mycobacterium leprae | PROBABLE D-AMINO ACID OXIDASE AAO | 0.0162 | 0.2211 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0099 | 0.1242 | 0.1242 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0099 | 0.1242 | 0.3646 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0099 | 0.1242 | 0.3646 |
Brugia malayi | nuclear receptor NHR-88 | 0.0099 | 0.1242 | 0.1242 |
Echinococcus granulosus | hormone sensitive lipase | 0.0223 | 0.3138 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0241 | 0.3408 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0031 | 0.0031 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0069 | 0.0789 | 0.3886 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0099 | 0.1242 | 0.1641 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0047 | 0.0451 | 0.0451 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.0682 | 0.2001 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0021 | 0.0068 | 0.02 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0099 | 0.1242 | 0.3646 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0099 | 0.1242 | 0.3646 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0096 | 0.1208 | 0.385 |
Echinococcus granulosus | FTZ F1 alpha | 0.0099 | 0.1242 | 0.3959 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.0146 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0146 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0451 | 0.0451 |
Loa Loa (eye worm) | hypothetical protein | 0.0188 | 0.26 | 0.26 |
Schistosoma mansoni | nuclear receptor | 0.0047 | 0.0451 | 0.1324 |
Brugia malayi | Matrixin family protein | 0.0127 | 0.1678 | 0.1678 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0327 | 0.1377 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.0682 | 0.0682 |
Brugia malayi | follicle stimulating hormone receptor | 0.0235 | 0.3321 | 0.3321 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0025 | 0.0128 | 0.0445 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0096 | 0.1208 | 0.1208 |
Brugia malayi | nuclear hormone receptor | 0.0099 | 0.1242 | 0.1242 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0099 | 0.1242 | 0.3959 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.1242 | 0.1242 |
Brugia malayi | Matrix metalloprotease, N-terminal domain containing protein | 0.0064 | 0.0719 | 0.0719 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0087 | 0.1065 | 0.3126 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0099 | 0.1242 | 0.1242 |
Brugia malayi | nuclear receptor NHR-88 | 0.0047 | 0.0451 | 0.0451 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0099 | 0.1242 | 0.3646 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.0087 | 0.1065 | 0.5302 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0682 | 0.2001 |
Brugia malayi | MH2 domain containing protein | 0.0116 | 0.1511 | 0.1511 |
Mycobacterium tuberculosis | Probable peptidoglycan hydrolase | 0.0064 | 0.0719 | 0.3532 |
Mycobacterium tuberculosis | Probable D-amino acid oxidase Aao | 0.0149 | 0.2006 | 1 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0047 | 0.0451 | 0.0451 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0099 | 0.1242 | 0.3646 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.0128 | 0.0445 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0099 | 0.1242 | 0.3959 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.0682 | 0.0682 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0128 | 0.0128 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0047 | 0.0451 | 0.1324 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0031 | 0.0031 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0099 | 0.1242 | 0.1242 |
Onchocerca volvulus | 0.0075 | 0.0878 | 0.1105 | |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0047 | 0.0451 | 0.0451 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0719 | 0.0719 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.1242 | 0.1242 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.0682 | 0.0682 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0099 | 0.1242 | 0.3646 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0047 | 0.0451 | 0.1438 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0047 | 0.0451 | 0.1438 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0047 | 0.0451 | 0.1324 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0031 | 0.0031 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.005 | 0.0507 | 0.1487 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0145 | 0.1949 | 0.5718 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0096 | 0.1208 | 0.3546 |
Schistosoma mansoni | lamin | 0.0026 | 0.0146 | 0.0428 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0052 | 0.0536 | 0.0536 |
Schistosoma mansoni | hormone-sensitive lipase (S09 family) | 0.0223 | 0.3138 | 0.9209 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0099 | 0.1242 | 0.1242 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0053 | 0.0552 | 0.0552 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0099 | 0.1242 | 0.3959 |
Schistosoma mansoni | zinc finger protein | 0.0047 | 0.0451 | 0.1324 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0099 | 0.1242 | 0.1242 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0099 | 0.1242 | 0.3959 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0025 | 0.0128 | 0.0321 |
Schistosoma mansoni | hormone-sensitive lipase (S09 family) | 0.0223 | 0.3138 | 0.9209 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0047 | 0.0451 | 0.1438 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0507 | 0.0507 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0451 | 0.0451 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0099 | 0.1242 | 0.1242 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0025 | 0.0128 | 0.0445 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0047 | 0.0451 | 0.1324 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0021 | 0.0068 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0099 | 0.1242 | 0.1242 |
Schistosoma mansoni | hypothetical protein | 0.0157 | 0.213 | 0.6251 |
Brugia malayi | tailless protein | 0.0047 | 0.0451 | 0.0451 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0145 | 0.1949 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0069 | 0.0789 | 0.3476 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0143 | 0.191 | 0.5605 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0544 | 0.0544 |
Loa Loa (eye worm) | matrix metalloproteinase | 0.0053 | 0.0544 | 0.0544 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0296 | 0.087 |
Brugia malayi | RNA binding protein | 0.0062 | 0.0682 | 0.0682 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.1058 | 0.1058 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0041 | 0.0364 | 0.0364 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0327 | 0.1377 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.005 | 0.0507 | 0.1615 |
Echinococcus granulosus | lamin | 0.0026 | 0.0146 | 0.0465 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0099 | 0.1242 | 0.3646 |
Onchocerca volvulus | 0.0472 | 0.6915 | 1 | |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0025 | 0.0128 | 0.0321 |
Brugia malayi | Protein kinase domain containing protein | 0.0087 | 0.1065 | 0.1065 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0052 | 0.0536 | 0.1708 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0099 | 0.1242 | 0.3646 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0047 | 0.0451 | 0.1438 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0145 | 0.1949 | 1 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0084 | 0.102 | 0.3252 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0682 | 0.2001 |
Loa Loa (eye worm) | hypothetical protein | 0.0472 | 0.6915 | 0.6915 |
Schistosoma mansoni | nuclear hormone receptor | 0.0047 | 0.0451 | 0.1324 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0021 | 0.0068 | 0.0263 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0451 | 0.0451 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.0087 | 0.1065 | 0.1065 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0038 | 0.0327 | 0.096 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0145 | 0.1949 | 0.1949 |
Onchocerca volvulus | 0.0047 | 0.0451 | 0.0475 | |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0069 | 0.0789 | 0.3834 |
Schistosoma mansoni | ap endonuclease | 0.0021 | 0.0068 | 0.02 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0099 | 0.1242 | 0.1242 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0099 | 0.1242 | 0.3959 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0099 | 0.1242 | 0.3646 |
Mycobacterium ulcerans | D-amino acid oxidase Aao | 0.0162 | 0.2211 | 1 |
Brugia malayi | Matrixin family protein | 0.0053 | 0.0544 | 0.0544 |
Echinococcus granulosus | jun protein | 0.0193 | 0.268 | 0.854 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0019 | 0.0031 | 0.0079 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0099 | 0.1242 | 0.1242 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0096 | 0.1208 | 0.3546 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.1242 | 0.1242 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0069 | 0.0789 | 0.2514 |
Schistosoma mansoni | hypothetical protein | 0.0075 | 0.0878 | 0.2578 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0053 | 0.0552 | 0.0552 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.002 | 0.0046 | 0.0136 |
Brugia malayi | ecdysone receptor | 0.0047 | 0.0451 | 0.0451 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0536 | 0.0536 |
Brugia malayi | hypothetical protein | 0.0152 | 0.205 | 0.205 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0235 | 0.3321 | 0.3321 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0116 | 0.1511 | 0.1511 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0084 | 0.102 | 0.2994 |
Brugia malayi | hypothetical protein | 0.0472 | 0.6915 | 0.6915 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.0682 | 0.0682 |
Brugia malayi | AMP-binding enzyme family protein | 0.0025 | 0.0128 | 0.0128 |
Loa Loa (eye worm) | matrixin family protein | 0.0127 | 0.1678 | 0.1678 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0047 | 0.0451 | 0.0451 |
Mycobacterium leprae | PROBABLE HYDROLASE | 0.0064 | 0.0719 | 0.2833 |
Brugia malayi | ecdysteroid receptor | 0.0099 | 0.1242 | 0.1242 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0021 | 0.0068 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0675 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0099 | 0.1242 | 0.3646 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0327 | 0.1377 |
Echinococcus granulosus | dual specificity | 0.0087 | 0.1065 | 0.3394 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0069 | 0.0789 | 0.2315 |
Schistosoma mansoni | coup transcription factor | 0.0099 | 0.1242 | 0.3646 |
Echinococcus multilocularis | matrix metallopeptidase 7 (M10 family) | 0.0191 | 0.2652 | 0.7782 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0047 | 0.0451 | 0.0451 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0451 | 0.0451 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0536 | 0.0536 |
Onchocerca volvulus | Matrix metalloproteinase homolog | 0.0117 | 0.1518 | 0.2048 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0145 | 0.1949 | 0.5718 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0099 | 0.1242 | 0.1242 |
Loa Loa (eye worm) | hypothetical protein | 0.0472 | 0.6915 | 0.6915 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0146 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0544 | 0.0544 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0099 | 0.1242 | 0.3646 |
Brugia malayi | hypothetical protein | 0.0047 | 0.0451 | 0.0451 |
Onchocerca volvulus | 0.0047 | 0.0451 | 0.0475 | |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0025 | 0.0128 | 0.0445 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0099 | 0.1242 | 0.3646 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0069 | 0.0789 | 0.3476 |
Schistosoma mansoni | lamin | 0.0026 | 0.0146 | 0.0428 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0099 | 0.1242 | 0.1641 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0146 | 0.0146 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0069 | 0.0789 | 0.2315 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0087 | 0.1065 | 0.5302 |
Entamoeba histolytica | protein kinase, putative | 0.0087 | 0.1065 | 0.5302 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0087 | 0.1065 | 0.5302 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0099 | 0.1242 | 0.1242 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0047 | 0.0451 | 0.1438 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0099 | 0.1242 | 0.1242 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0116 | 0.1511 | 0.1511 |
Schistosoma mansoni | nuclear receptor | 0.0047 | 0.0451 | 0.1324 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0544 | 0.0544 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0451 | 0.0451 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0099 | 0.1242 | 0.1242 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0145 | 0.1949 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.0128 | 0.0445 |
Echinococcus multilocularis | Protein lozenge | 0.0059 | 0.0644 | 0.189 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0451 | 0.0451 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0052 | 0.0536 | 0.1573 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0052 | 0.0536 | 0.0536 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0451 | 0.0451 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0099 | 0.1242 | 0.3646 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0451 | 0.0451 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0099 | 0.1242 | 0.3959 |
Loa Loa (eye worm) | DR-78 | 0.0047 | 0.0451 | 0.0451 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.0128 | 0.0321 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0145 | 0.1949 | 0.621 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0025 | 0.0128 | 0.0445 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0099 | 0.1242 | 0.1641 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0069 | 0.0789 | 0.3476 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.0146 | 0.0428 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0143 | 0.191 | 0.6087 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0031 | 0.0031 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0536 | 0.0536 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0025 | 0.0128 | 0.0321 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.0682 | 0.0682 |
Loa Loa (eye worm) | runx1 | 0.0059 | 0.0644 | 0.0644 |
Echinococcus granulosus | matrix metallopeptidase 7 M10 family | 0.0191 | 0.2652 | 0.8451 |
Onchocerca volvulus | 0.0099 | 0.1242 | 0.1641 | |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0047 | 0.0451 | 0.1324 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0451 | 0.0451 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0327 | 0.1377 |
Onchocerca volvulus | Matrilysin homolog | 0.0053 | 0.0544 | 0.0613 |
Brugia malayi | nuclear receptor RXR | 0.0052 | 0.0536 | 0.0536 |
Brugia malayi | hypothetical protein | 0.0047 | 0.0451 | 0.0451 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0145 | 0.1949 | 0.1949 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0025 | 0.0128 | 0.0566 |
Loa Loa (eye worm) | hypothetical protein | 0.0223 | 0.3138 | 0.3138 |
Mycobacterium ulcerans | hypothetical protein | 0.0025 | 0.0128 | 0.0445 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0682 | 0.2001 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0069 | 0.0789 | 0.2315 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0021 | 0.0068 | 0.0217 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0047 | 0.0451 | 0.0451 |
Brugia malayi | nuclear hormone receptor | 0.0047 | 0.0451 | 0.0451 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0536 | 0.0536 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription factor | 0.0193 | 0.268 | 0.7865 |
Brugia malayi | metabotropic glutamate receptor type 2 | 0.002 | 0.0046 | 0.0046 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0128 | 0.0128 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0096 | 0.1208 | 0.1208 |
Echinococcus granulosus | metabotropic glutamate receptor 2 | 0.0034 | 0.0263 | 0.0839 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0047 | 0.0451 | 0.1324 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0096 | 0.1208 | 0.3546 |
Brugia malayi | conserved hypotetical protein | 0.0047 | 0.0451 | 0.0451 |
Brugia malayi | steroid hormone receptor | 0.0099 | 0.1242 | 0.1242 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0019 | 0.0031 | 0.5 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0069 | 0.0789 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0099 | 0.1242 | 0.3646 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0025 | 0.0128 | 0.0445 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.0682 | 0.2001 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0021 | 0.0068 | 1 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0047 | 0.0451 | 0.0475 |
Onchocerca volvulus | 0.0026 | 0.0146 | 0.0026 | |
Schistosoma mansoni | nuclear hormone receptor | 0.0047 | 0.0451 | 0.1324 |
Brugia malayi | hypothetical protein | 0.0038 | 0.0327 | 0.0327 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.