Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Plasmodium vivax | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.199 | 0.5348 | 1 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.1286 | 0.3267 | 0.6108 |
Loa Loa (eye worm) | ACC-1 protein | 0.0826 | 0.1904 | 0.1355 |
Leishmania major | glyceraldehyde-3-phosphate dehydrogenase-like protein | 0.1847 | 0.4926 | 0.921 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0826 | 0.1904 | 0.1768 |
Echinococcus multilocularis | neuronal acetylcholine receptor subunit alpha 4 | 0.0826 | 0.1904 | 0.356 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0397 | 0.0634 | 0.1186 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Plasmodium vivax | tryptophan-rich antigen (Pv-fam-a) | 0.1827 | 0.4867 | 0.9012 |
Echinococcus granulosus | nicotinic acetylcholine receptor beta 1 subunit | 0.0826 | 0.1904 | 0.356 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit type | 0.0397 | 0.0634 | 0.1186 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | glyceraldehyde 3-phosphate dehydrogenase | 0.1286 | 0.3267 | 0.2811 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Echinococcus granulosus | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative | 0.0632 | 0.1331 | 0.2489 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0826 | 0.1904 | 0.1768 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0826 | 0.1904 | 0.356 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Echinococcus granulosus | nicotinic acetylcholine receptor a11 subunit | 0.0826 | 0.1904 | 0.356 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.0623 | 0.1303 | 0.933 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | LGC-31 protein | 0.0826 | 0.1904 | 0.1355 |
Brugia malayi | nicotinic acetylcholine receptor beta-1 chain precursor | 0.0826 | 0.1904 | 0.1768 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Leishmania major | acetyl-CoA carboxylase, putative | 0.0478 | 0.0876 | 0.1638 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Brugia malayi | gamma-aminobutyric-acid receptor beta subunit precursor | 0.2823 | 0.7814 | 1 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Echinococcus granulosus | nAChR subunit | 0.0429 | 0.0731 | 0.1366 |
Brugia malayi | glyceraldehyde 3-phosphate dehydrogenase | 0.0632 | 0.1331 | 0.097 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Loa Loa (eye worm) | ACC-1 protein | 0.0826 | 0.1904 | 0.1355 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0429 | 0.0731 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Toxoplasma gondii | glyceraldehyde-3-phosphate dehydrogenase GAPDH2 | 0.199 | 0.5348 | 1 |
Brugia malayi | acetylcholine receptor, alpha-type subunit unc-38 precursor | 0.0826 | 0.1904 | 0.1768 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1286 | 0.3267 | 0.4531 |
Echinococcus multilocularis | gamma aminobutyric acid receptor subunit | 0.0397 | 0.0634 | 0.1186 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Trypanosoma cruzi | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.1847 | 0.4926 | 0.921 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0826 | 0.1904 | 0.356 |
Brugia malayi | excitatory GABA receptor EXP-1A | 0.0826 | 0.1904 | 0.1768 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Echinococcus multilocularis | glycine receptor subunit beta | 0.0826 | 0.1904 | 0.356 |
Toxoplasma gondii | acetyl-CoA carboxylase ACC1 | 0.0478 | 0.0876 | 0.1638 |
Toxoplasma gondii | acetyl-coA carboxylase ACC2 | 0.0478 | 0.0876 | 0.1638 |
Onchocerca volvulus | 0.0429 | 0.0731 | 0.0758 | |
Brugia malayi | Cation transporter family protein | 0.0826 | 0.1904 | 0.1768 |
Brugia malayi | acetylcholine receptor protein, alpha-like chain, putative | 0.0826 | 0.1904 | 0.1768 |
Brugia malayi | Glyceraldehyde 3-phosphate dehydrogenase | 0.199 | 0.5348 | 0.6565 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit type | 0.0826 | 0.1904 | 0.356 |
Onchocerca volvulus | 0.0429 | 0.0731 | 0.0758 | |
Loa Loa (eye worm) | glutamate-gated chloride channel alpha3A subunit | 0.0826 | 0.1904 | 0.1355 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Echinococcus granulosus | gamma aminobutyric acid receptor subunit | 0.0397 | 0.0634 | 0.1186 |
Echinococcus multilocularis | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Schistosoma mansoni | acetyl-CoA carboxylase | 0.0478 | 0.0876 | 0.1638 |
Loa Loa (eye worm) | GABA receptor subunit | 0.0429 | 0.0731 | 0.0103 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | glyceraldehyde-3-phosphate dehydrogenase | 0.1358 | 0.3478 | 0.3036 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0429 | 0.0731 | 0.1366 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.199 | 0.5348 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0632 | 0.1331 | 0.2489 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Brugia malayi | nicotinic acetylcholine receptor alpha subunit, putative | 0.0826 | 0.1904 | 0.1768 |
Wolbachia endosymbiont of Brugia malayi | glyceraldehyde-3-phosphate dehydrogenase, GapA | 0.199 | 0.5348 | 1 |
Trypanosoma cruzi | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.1847 | 0.4926 | 0.921 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0632 | 0.1331 | 0.2489 |
Echinococcus multilocularis | nicotinic acetylcholine receptor alpha subunit | 0.0826 | 0.1904 | 0.356 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0429 | 0.0731 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta2-like) | 0.0826 | 0.1904 | 0.356 |
Schistosoma mansoni | nicotinic acetylcholine receptor alpha | 0.0429 | 0.0731 | 0.1366 |
Chlamydia trachomatis | glyceraldehyde-3-phosphate dehydrogenase | 0.199 | 0.5348 | 0.5 |
Schistosoma mansoni | nAChR subunit (ShAR1-beta-like) | 0.0826 | 0.1904 | 0.356 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative | 0.0632 | 0.1331 | 0.2489 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0429 | 0.0731 | 0.0134 |
Schistosoma mansoni | acetylcholine receptor subunit beta | 0.0397 | 0.0634 | 0.1186 |
Trypanosoma brucei | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.1847 | 0.4926 | 0.921 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0397 | 0.0634 | 0.1186 |
Echinococcus granulosus | acetylcholine receptor subunit beta 1 | 0.0826 | 0.1904 | 0.356 |
Brugia malayi | Hypothetical glycine receptor like protein T20B12.9 in chromosome III | 0.0826 | 0.1904 | 0.1768 |
Schistosoma mansoni | Cys-loop ligand gated ion channel subunit | 0.0826 | 0.1904 | 0.356 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.199 | 0.5348 | 1 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0826 | 0.1904 | 0.356 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Echinococcus multilocularis | nicotinic acetylcholine receptor a11 subunit | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | ligand-Gated ion Channel family member | 0.0826 | 0.1904 | 0.1355 |
Onchocerca volvulus | Putative nachr subunit | 0.0826 | 0.1904 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Leishmania major | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.199 | 0.5348 | 1 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1286 | 0.3267 | 0.2811 |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Brugia malayi | Neurotransmitter-gated ion-channel transmembrane region family protein | 0.0826 | 0.1904 | 0.1768 |
Brugia malayi | acetylcholine receptor alpha subunit precursor, putative | 0.0826 | 0.1904 | 0.1768 |
Echinococcus multilocularis | nicotinic acetylcholine receptor beta 1 subunit | 0.0826 | 0.1904 | 0.356 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Echinococcus granulosus | Cys loop ligand gated ion channel subunit | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0429 | 0.0731 | 0.1366 |
Echinococcus multilocularis | Cys loop ligand gated ion channel subunit | 0.0397 | 0.0634 | 0.1186 |
Trypanosoma cruzi | acetyl-CoA carboxylase | 0.0296 | 0.0337 | 0.063 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.199 | 0.5348 | 1 |
Schistosoma mansoni | nAChR subunit (ShAR1-alpha-like) | 0.0826 | 0.1904 | 0.356 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.1286 | 0.3267 | 0.4531 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, cytosolic | 0.199 | 0.5348 | 1 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | acetylcholine receptor alpha subunit | 0.0826 | 0.1904 | 0.1355 |
Loa Loa (eye worm) | carboxyl transferase domain-containing protein | 0.0461 | 0.0826 | 0.0205 |
Echinococcus granulosus | neuronal acetylcholine receptor subunit alpha 4 | 0.0826 | 0.1904 | 0.356 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.1286 | 0.3267 | 0.6108 |
Brugia malayi | glutamate-gated chloride channel alpha3A subunit, putative | 0.0429 | 0.0731 | 0.0134 |
Toxoplasma gondii | glyceraldehyde-3-phosphate dehydrogenase GAPDH1 | 0.199 | 0.5348 | 1 |
Echinococcus granulosus | acetyl coenzyme A carboxylase 1 | 0.0478 | 0.0876 | 0.1638 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Brugia malayi | Carboxyl transferase domain containing protein | 0.0461 | 0.0826 | 0.0267 |
Giardia lamblia | Glyceraldehyde 3-phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Onchocerca volvulus | 0.0826 | 0.1904 | 1 | |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.199 | 0.5348 | 1 |
Trypanosoma brucei | acetyl-CoA carboxylase | 0.0478 | 0.0876 | 0.1638 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.067 | 0.1443 | 0.2698 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor non-alpha subunit | 0.0826 | 0.1904 | 0.1355 |
Brugia malayi | Glyceraldehyde 3-phosphate dehydrogenase | 0.0703 | 0.1542 | 0.1265 |
Loa Loa (eye worm) | glyceraldehyde 3-phosphate dehydrogenase | 0.1286 | 0.3267 | 0.2811 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Loa Loa (eye worm) | hypothetical protein | 0.2427 | 0.6641 | 0.6413 |
Mycobacterium ulcerans | glyceraldehyde 3-phosphate dehydrogenase Gap | 0.199 | 0.5348 | 1 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Schistosoma mansoni | neurotransmitter gated ion channel | 0.0397 | 0.0634 | 0.1186 |
Echinococcus multilocularis | acetyl coenzyme A carboxylase 1 | 0.0478 | 0.0876 | 0.1638 |
Brugia malayi | Neurotransmitter-gated ion-channel ligand binding domain containing protein | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | glyceraldehyde-3-phosphate dehydrogenase | 0.1358 | 0.3478 | 0.3036 |
Echinococcus multilocularis | nAChR subunit | 0.0429 | 0.0731 | 0.1366 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.199 | 0.5348 | 1 |
Echinococcus granulosus | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Brugia malayi | Cation transporter family protein | 0.0826 | 0.1904 | 0.1768 |
Schistosoma mansoni | nAChR subunit | 0.0826 | 0.1904 | 0.356 |
Mycobacterium tuberculosis | Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) | 0.0654 | 0.1397 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Brugia malayi | Cation transporter family protein | 0.0826 | 0.1904 | 0.1768 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Loa Loa (eye worm) | nicotinic acetylcholine receptor alpha subunit | 0.0826 | 0.1904 | 0.1355 |
Echinococcus multilocularis | acetylcholine receptor subunit beta 1 | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Echinococcus multilocularis | glycine receptor subunit alpha 1 | 0.0826 | 0.1904 | 0.356 |
Entamoeba histolytica | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Treponema pallidum | glyceraldehyde 3-phosphate dehydrogenase (gap) | 0.199 | 0.5348 | 0.5 |
Schistosoma mansoni | nAChR subunit | 0.0397 | 0.0634 | 0.1186 |
Schistosoma mansoni | nAChR subunit | 0.0397 | 0.0634 | 0.1186 |
Schistosoma mansoni | acetylcholine receptor-related | 0.0397 | 0.0634 | 0.1186 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.067 | 0.1443 | 0.2698 |
Mycobacterium leprae | Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) | 0.0654 | 0.1397 | 1 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.199 | 0.5348 | 1 |
Echinococcus granulosus | nicotinic acetylcholine receptor alpha subunit | 0.0826 | 0.1904 | 0.356 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0632 | 0.1331 | 0.2489 |
Loa Loa (eye worm) | excitatory GABA receptor EXP-1A | 0.0826 | 0.1904 | 0.1355 |
Leishmania major | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.199 | 0.5348 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0731 | 0.0103 |
Loa Loa (eye worm) | hypothetical protein | 0.2823 | 0.7814 | 0.7666 |
Echinococcus granulosus | nicotinic acetylcholine receptor subunit alpha 8 | 0.0826 | 0.1904 | 0.356 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.199 | 0.5348 | 1 |
Echinococcus multilocularis | nicotinic acetylcholine receptor subunit alpha 8 | 0.0826 | 0.1904 | 0.356 |
Echinococcus granulosus | glycine receptor subunit beta | 0.0826 | 0.1904 | 0.356 |
Loa Loa (eye worm) | hypothetical protein | 0.0826 | 0.1904 | 0.1355 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.199 | 0.5348 | 1 |
Plasmodium falciparum | glyceraldehyde-3-phosphate dehydrogenase | 0.199 | 0.5348 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | >= 10 % | The ability of the compound to inhibit platelet aggregation was tested; Inhibition >= 10% but < aspirin (34-96%) | ChEMBL. | 3373489 |
Reduction (functional) | = 20 % | Hypolipidemic activity of the compound was expressed as percent decrease in serum cholesterol in Sprague-Dawley rats | ChEMBL. | 3373489 |
Reduction (functional) | = 31 % | Hypolipidemic activity of the compound was expressed as percent decrease in triglycerides in Sprague-Dawley rats | ChEMBL. | 3373489 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.