Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | biotin carboxylase subunit of acetyl CoA carboxylase, putative | 0.0486 | 0.5786 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0331 | 0.3841 | 0.6292 |
Echinococcus multilocularis | propionyl coenzyme A carboxylase beta chain | 0.0091 | 0.0844 | 0.0844 |
Schistosoma mansoni | transient receptor potential channel 4 | 0.0108 | 0.1053 | 0.1298 |
Trypanosoma brucei | unspecified product | 0.0168 | 0.181 | 0.2232 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0045 | 0.0273 | 0.0336 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0536 | 0.0685 |
Mycobacterium ulcerans | carbamoyl phosphate synthase large subunit | 0.0058 | 0.0429 | 0.1476 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0045 | 0.0273 | 0.0556 |
Toxoplasma gondii | ABC1 family protein | 0.0037 | 0.0163 | 0.0201 |
Mycobacterium ulcerans | acetyl/propionyl CoA carboxylase subunit beta | 0.0091 | 0.0844 | 0.2905 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0037 | 0.0163 | 0.0201 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0071 | 0.0597 | 0.0736 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0163 | 0.056 |
Echinococcus multilocularis | GPCR, family 2 | 0.0031 | 0.009 | 0.009 |
Leishmania major | propionyl-coa carboxylase beta chain, putative | 0.0091 | 0.0844 | 0.1041 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.019 | 0.2084 | 0.2084 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0163 | 0.0208 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0037 | 0.0163 | 0.0201 |
Mycobacterium ulcerans | lipase LipD | 0.0037 | 0.0163 | 0.056 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.0406 | 0.4785 | 0.5902 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.019 | 0.2084 | 0.2084 |
Echinococcus granulosus | bile acid beta glucosidase | 0.0406 | 0.4785 | 0.5902 |
Trypanosoma cruzi | 3-methylcrotonyl-CoA carboxylase, putative | 0.0256 | 0.2906 | 0.5922 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0504 | 0.6008 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0097 | 0.092 | 0.1177 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0054 | 0.0375 | 0.048 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0262 | 0.2987 | 0.2987 |
Echinococcus granulosus | geminin | 0.0165 | 0.1771 | 0.2184 |
Loa Loa (eye worm) | hypothetical protein | 0.0309 | 0.3565 | 0.4562 |
Chlamydia trachomatis | biotin carboxylase | 0.0232 | 0.2612 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0097 | 0.092 | 0.1177 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0037 | 0.0163 | 0.0208 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0331 | 0.3841 | 0.6292 |
Trypanosoma brucei | 3-methylcrotonyl-CoA carboxylase alpha subunit, putative | 0.0256 | 0.2906 | 0.3584 |
Giardia lamblia | Ceramide glucosyltransferase | 0.0211 | 0.2345 | 0.5395 |
Schistosoma mansoni | survival motor neuron protein | 0.0054 | 0.0375 | 0.0463 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0037 | 0.0163 | 0.056 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0293 | 0.3375 | 0.5494 |
Echinococcus multilocularis | TRP (transient receptor potential) channel | 0.004 | 0.0207 | 0.0207 |
Toxoplasma gondii | acetyl-coA carboxylase ACC2 | 0.0672 | 0.8108 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.0536 | 0.0661 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.019 | 0.2084 | 0.2668 |
Echinococcus multilocularis | non lysosomal glucosylceramidase | 0.0406 | 0.4785 | 0.4785 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0163 | 0.0332 |
Toxoplasma gondii | pyruvate carboxylase | 0.0256 | 0.2906 | 0.3584 |
Echinococcus multilocularis | ceramide glucosyltransferase | 0.0465 | 0.5527 | 0.5527 |
Leishmania major | carbamoyl-phosphate synthase, putative | 0.0058 | 0.0429 | 0.0529 |
Brugia malayi | Carboxyl transferase domain containing protein | 0.0648 | 0.7814 | 1 |
Mycobacterium ulcerans | propionyl-CoA carboxylase beta chain 4 AccD4 | 0.0091 | 0.0844 | 0.2905 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.019 | 0.2084 | 0.2571 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0153 | 0.1614 | 0.1991 |
Mycobacterium leprae | Probable bifunctional protein acetyl-/propionyl-coenzyme A carboxylase, alpha chain AccA3 (BccP) | 0.0256 | 0.2906 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0067 | 0.0542 | 0.0669 |
Mycobacterium ulcerans | propionyl-CoA carboxylase beta chain 5 AccD5 | 0.0091 | 0.0844 | 0.2905 |
Mycobacterium ulcerans | hypothetical protein | 0.017 | 0.183 | 0.6296 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0031 | 0.009 | 0.0115 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0097 | 0.092 | 0.1177 |
Schistosoma mansoni | methylcrotonyl-CoA carboxylase | 0.0256 | 0.2906 | 0.3584 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0163 | 0.0208 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.0465 | 0.5527 | 0.6817 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0013 | 0.0022 |
Onchocerca volvulus | 0.0309 | 0.3565 | 0.6341 | |
Loa Loa (eye worm) | carboxyl transferase domain-containing protein | 0.0648 | 0.7814 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0067 | 0.0542 | 0.0542 |
Echinococcus multilocularis | transient receptor potential gamma protein | 0.0108 | 0.1053 | 0.1053 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0162 | 0.0207 |
Wolbachia endosymbiont of Brugia malayi | carbamoyl phosphate synthase large subunit | 0.0058 | 0.0429 | 0.1476 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0293 | 0.3375 | 0.5494 |
Echinococcus multilocularis | geminin | 0.0165 | 0.1771 | 0.1771 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0293 | 0.3375 | 0.5494 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0262 | 0.2987 | 0.3685 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.0143 | 0.1498 | 0.5154 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0504 | 0.6008 | 0.769 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.019 | 0.2084 | 0.2571 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.009 | 0.0111 |
Brugia malayi | Ceramide glucosyltransferase | 0.0465 | 0.5527 | 0.7074 |
Mycobacterium ulcerans | acetyl-/propionyl-coenzyme a carboxylase alpha chain, AccA2 | 0.0256 | 0.2906 | 1 |
Echinococcus granulosus | TRP transient receptor potential channel | 0.004 | 0.0207 | 0.0255 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0322 | 0.3738 | 0.7617 |
Mycobacterium ulcerans | bifunctional protein acetyl-/propionyl-coenzyme a carboxylase (alpha chain) AccA3 | 0.0256 | 0.2906 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0504 | 0.6008 | 1 |
Chlamydia trachomatis | acetyl-coenzyme A carboxylase carboxyl transferase subunit beta | 0.0091 | 0.0844 | 0.3233 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.0465 | 0.5527 | 0.6817 |
Loa Loa (eye worm) | ceramide glucosyltransferase | 0.0465 | 0.5527 | 0.7074 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.1771 | 0.2184 |
Leishmania major | 3-methylcrotonoyl-CoA carboxylase beta subunit, putative | 0.0091 | 0.0844 | 0.1041 |
Mycobacterium leprae | conserved hypothetical protein | 0.0037 | 0.0163 | 0.056 |
Schistosoma mansoni | propionyl-CoA carboxylase beta chain mitochondrial precursor | 0.0091 | 0.0844 | 0.1041 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0037 | 0.0163 | 0.056 |
Brugia malayi | beta-lactamase | 0.0037 | 0.0163 | 0.0208 |
Mycobacterium ulcerans | propionyl-CoA carboxylase beta chain 4 AccD4_2 | 0.0091 | 0.0844 | 0.2905 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0153 | 0.1614 | 0.1991 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0163 | 0.0208 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0037 | 0.0163 | 0.056 |
Loa Loa (eye worm) | hypothetical protein | 0.0274 | 0.3135 | 0.4012 |
Echinococcus multilocularis | transient receptor potential ion channel A | 0.0104 | 0.1008 | 0.1008 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0055 | 0.0397 | 0.0808 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0013 | 0.0026 |
Echinococcus multilocularis | acetylcholinesterase | 0.0067 | 0.0542 | 0.0542 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.009 | 0.0111 |
Echinococcus multilocularis | acetyl coenzyme A carboxylase 1 | 0.0672 | 0.8108 | 0.8108 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.1053 | 0.1347 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.009 | 0.0115 |
Mycobacterium tuberculosis | Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA2: biotin carboxylase + biotin carboxyl carrie | 0.0256 | 0.2906 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.019 | 0.2084 | 0.2571 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0504 | 0.6008 | 1 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0293 | 0.3375 | 1 |
Mycobacterium tuberculosis | Probable propionyl-CoA carboxylase beta chain 5 AccD5 (pccase) (propanoyl-CoA:carbon dioxide ligase) | 0.0091 | 0.0844 | 0.2905 |
Brugia malayi | Carboxylesterase family protein | 0.0067 | 0.0542 | 0.0694 |
Schistosoma mansoni | acetyl-CoA carboxylase | 0.0672 | 0.8108 | 1 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0037 | 0.0163 | 0.0208 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0322 | 0.3738 | 0.7617 |
Echinococcus granulosus | acetylcholinesterase | 0.0067 | 0.0542 | 0.0669 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.019 | 0.2084 | 0.2571 |
Trypanosoma cruzi | 3-methylcrotonyl-CoA carboxylase, putative | 0.0256 | 0.2906 | 0.5922 |
Brugia malayi | hypothetical protein | 0.0262 | 0.2987 | 0.3823 |
Wolbachia endosymbiont of Brugia malayi | Acetyl/propionyl-CoA carboxylase, alpha subunit | 0.0256 | 0.2906 | 1 |
Plasmodium falciparum | biotin carboxylase subunit of acetyl CoA carboxylase, putative | 0.0486 | 0.5786 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0045 | 0.0273 | 0.0556 |
Trypanosoma cruzi | acetyl-CoA carboxylase | 0.0416 | 0.4908 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0293 | 0.3375 | 0.5494 |
Trypanosoma brucei | 3-methylcrotonoyl-CoA carboxylase beta subunit, putative | 0.0091 | 0.0844 | 0.1041 |
Echinococcus multilocularis | propionyl coenzyme A carboxylase alpha chain | 0.0256 | 0.2906 | 0.2906 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0071 | 0.0597 | 0.0736 |
Schistosoma mansoni | transient receptor potential channel | 0.0071 | 0.0597 | 0.0736 |
Toxoplasma gondii | hypothetical protein | 0.0052 | 0.0356 | 0.0439 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0163 | 0.056 |
Echinococcus multilocularis | bile acid beta glucosidase | 0.0406 | 0.4785 | 0.4785 |
Mycobacterium leprae | Probable lipase LipE | 0.0037 | 0.0163 | 0.056 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0331 | 0.3841 | 0.6292 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0037 | 0.0163 | 0.056 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0071 | 0.0597 | 0.0597 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0331 | 0.3841 | 0.6292 |
Mycobacterium leprae | Probable propionyl-CoA carboxylase beta chain 5 AccD5 (PCCASE) (PROPANOYL-COA:CARBON DIOXIDE LIGASE) | 0.0091 | 0.0844 | 0.2905 |
Toxoplasma gondii | acetyl-CoA carboxylase ACC1 | 0.0672 | 0.8108 | 1 |
Schistosoma mansoni | carbamoyl-phosphate synthetase | 0.0058 | 0.0429 | 0.0529 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0163 | 0.0208 |
Trypanosoma cruzi | 3-methylcrotonoyl-CoA carboxylase beta subunit, putative | 0.0091 | 0.0844 | 0.172 |
Schistosoma mansoni | transient receptor potential channel | 0.0071 | 0.0597 | 0.0736 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0322 | 0.3738 | 0.461 |
Schistosoma mansoni | hypothetical protein | 0.0054 | 0.0375 | 0.0463 |
Brugia malayi | Transient-receptor-potential like protein | 0.004 | 0.0207 | 0.0265 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0066 | 0.0536 | 0.0685 |
Echinococcus granulosus | propionyl coenzyme A carboxylase beta chain | 0.0091 | 0.0844 | 0.1041 |
Mycobacterium ulcerans | hypothetical protein | 0.0037 | 0.0163 | 0.056 |
Trypanosoma brucei | acetyl-CoA carboxylase | 0.0672 | 0.8108 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0262 | 0.2987 | 0.3823 |
Toxoplasma gondii | acyl-CoA carboxyltransferase beta chain, putative | 0.0091 | 0.0844 | 0.1041 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0037 | 0.0163 | 0.056 |
Echinococcus granulosus | propionyl coenzyme A carboxylase alpha chain | 0.0256 | 0.2906 | 0.3584 |
Echinococcus granulosus | GPCR family 2 | 0.0031 | 0.009 | 0.0111 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0293 | 0.3375 | 0.5494 |
Mycobacterium ulcerans | pyruvate carboxylase | 0.0256 | 0.2906 | 1 |
Trypanosoma cruzi | glutamine dependent carbamoyl-phosphate synthase, putative | 0.0058 | 0.0429 | 0.0874 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.009 | 0.009 |
Brugia malayi | N-terminal motif family protein | 0.019 | 0.2077 | 0.2658 |
Schistosoma mansoni | methylcrotonyl-CoA carboxylase | 0.0256 | 0.2906 | 0.3584 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0504 | 0.6008 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.009 | 0.0111 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0037 | 0.0163 | 0.0163 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.019 | 0.2084 | 0.2571 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0013 | 0.0016 |
Echinococcus granulosus | non lysosomal glucosylceramidase | 0.0406 | 0.4785 | 0.5902 |
Leishmania major | methylcrotonoyl-coa carboxylase biotinylated subunitprotein-like protein | 0.0256 | 0.2906 | 0.3584 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0013 | 0.0016 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0348 | 0.4064 | 0.6673 |
Mycobacterium tuberculosis | Probable pyruvate carboxylase Pca (pyruvic carboxylase) | 0.0256 | 0.2906 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.009 | 0.0111 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.009 | 0.0111 |
Brugia malayi | beta-lactamase family protein | 0.0037 | 0.0163 | 0.0208 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0037 | 0.0163 | 0.056 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0331 | 0.3841 | 0.6292 |
Mycobacterium leprae | Probable propyonyl-CoA carboxylase beta chain 4 AccD4 (Pccase) | 0.0091 | 0.0844 | 0.2905 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0163 | 0.0201 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0504 | 0.6008 | 1 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.0143 | 0.1498 | 0.5154 |
Mycobacterium ulcerans | acetyl-/propionyl-CoA carboxylase subunit beta | 0.0091 | 0.0844 | 0.2905 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0293 | 0.3375 | 0.5494 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.0406 | 0.4785 | 0.5902 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0067 | 0.0542 | 0.0694 |
Schistosoma mansoni | carbamoyl-phosphate synthetase | 0.0058 | 0.0429 | 0.0529 |
Loa Loa (eye worm) | beta-lactamase | 0.0037 | 0.0163 | 0.0208 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.1771 | 0.2184 |
Schistosoma mansoni | pyruvate carboxylase | 0.0256 | 0.2906 | 0.3584 |
Echinococcus granulosus | acetylcholinesterase | 0.0067 | 0.0542 | 0.0669 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.009 | 0.0111 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.2077 | 0.2658 |
Mycobacterium leprae | ACETYL/PROPIONYL-CoA CARBOXYLASE (BETA SUBUNIT) ACCD6 | 0.0091 | 0.0844 | 0.2905 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0542 | 0.0694 |
Leishmania major | carboxylase, putative | 0.0256 | 0.2906 | 0.3584 |
Brugia malayi | Carboxylesterase family protein | 0.0067 | 0.0542 | 0.0694 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.092 | 0.1177 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0013 | 0.0016 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.017 | 0.183 | 0.6296 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0067 | 0.0542 | 0.0669 |
Mycobacterium ulcerans | acetyl-/propionyl-coenzyme a carboxylase alpha chain AccA1 | 0.0256 | 0.2906 | 1 |
Plasmodium vivax | carbamoyl phosphate synthetase, putative | 0.0058 | 0.0429 | 0.0742 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0037 | 0.0163 | 0.056 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0013 | 0.0022 |
Toxoplasma gondii | carbamoylphosphate synthetase | 0.0058 | 0.0429 | 0.0529 |
Loa Loa (eye worm) | carboxylesterase | 0.0067 | 0.0542 | 0.0694 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0031 | 0.009 | 0.0115 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0031 | 0.009 | 0.0115 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0504 | 0.6008 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0207 | 0.0265 |
Mycobacterium ulcerans | acetyl-coenzyme a carboxylase carboxyl transferase (subunit beta) AccD3 | 0.0091 | 0.0844 | 0.2905 |
Echinococcus granulosus | ceramide glucosyltransferase | 0.0465 | 0.5527 | 0.6817 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0037 | 0.0163 | 0.0332 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.019 | 0.2084 | 0.2668 |
Trypanosoma brucei | glutamine hydrolysing (not ammonia-dependent) carbomoyl phosphate synthase, putative | 0.0058 | 0.0429 | 0.0529 |
Plasmodium vivax | hypothetical protein, conserved | 0.0037 | 0.0163 | 0.0281 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0013 | 0.0026 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0348 | 0.4064 | 0.6673 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0504 | 0.6008 | 0.769 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0071 | 0.0597 | 0.0597 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0322 | 0.3738 | 0.461 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0037 | 0.0163 | 0.056 |
Schistosoma mansoni | aspartate carbamoyltransferase | 0.0058 | 0.0429 | 0.0529 |
Plasmodium falciparum | carbamoyl phosphate synthetase | 0.0058 | 0.0429 | 0.0742 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0331 | 0.3841 | 0.6292 |
Trypanosoma cruzi | glutamine-dependent carbamoyl-phosphate synthetase, putative | 0.0058 | 0.0429 | 0.0874 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0037 | 0.0163 | 0.056 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0163 | 0.0208 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0037 | 0.0163 | 0.0201 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0293 | 0.3375 | 1 |
Trypanosoma brucei | 3-methylcrotonyl-CoA carboxylase alpha subunit, putative | 0.0256 | 0.2906 | 0.3584 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0013 | 0.0016 |
Leishmania major | hypothetical protein, conserved | 0.0037 | 0.0163 | 0.0201 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.0143 | 0.1498 | 0.5154 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0331 | 0.3841 | 0.6292 |
Trypanosoma cruzi | acetyl-CoA carboxylase, putative | 0.0091 | 0.0844 | 0.172 |
Echinococcus granulosus | transient receptor potential ion channel A | 0.0104 | 0.1008 | 0.1243 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0153 | 0.1614 | 0.3289 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0293 | 0.3375 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.009 | 0.009 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0013 | 0.0022 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0045 | 0.0273 | 0.0556 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0163 | 0.0208 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0293 | 0.3375 | 0.5494 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0293 | 0.3375 | 1 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0013 | 0.0016 |
Echinococcus granulosus | transient receptor potential gamma protein | 0.0108 | 0.1053 | 0.1298 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0163 | 0.0208 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0552 | 0.0706 |
Schistosoma mansoni | transient receptor potential channel | 0.0108 | 0.1053 | 0.1298 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0067 | 0.0542 | 0.0542 |
Wolbachia endosymbiont of Brugia malayi | Acetyl-CoA carboxylase, carboxyltransferase component | 0.0091 | 0.0844 | 0.2905 |
Trypanosoma cruzi | 3-methylcrotonoyl-CoA carboxylase beta subunit, putative | 0.0091 | 0.0844 | 0.172 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0293 | 0.3375 | 0.5494 |
Leishmania major | acetyl-CoA carboxylase, putative | 0.0672 | 0.8108 | 1 |
Mycobacterium tuberculosis | Acetyl/propionyl-CoA carboxylase (beta subunit) AccD6 | 0.0091 | 0.0844 | 0.2905 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0233 | 0.2626 | 0.9035 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0542 | 0.0694 |
Onchocerca volvulus | Ceramide glucosyltransferase homolog | 0.0465 | 0.5527 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0037 | 0.0163 | 0.056 |
Mycobacterium ulcerans | beta-lactamase | 0.0037 | 0.0163 | 0.056 |
Brugia malayi | hypothetical protein | 0.0309 | 0.3565 | 0.4562 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0331 | 0.3841 | 0.6857 |
Echinococcus granulosus | acetyl coenzyme A carboxylase 1 | 0.0672 | 0.8108 | 1 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.019 | 0.2077 | 0.3567 |
Onchocerca volvulus | 0.0054 | 0.0375 | 0.0396 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 14 uM | In vitro inhibitory concentration that relaxed KCL induced contraction in rat detrusor strip by 50% | ChEMBL. | 10737753 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.