Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 1 | 1 |
Brugia malayi | intermediate filament protein | 0.0026 | 0.0767 | 0.0671 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0122 | 0.6016 | 0.6005 |
Schistosoma mansoni | thyroid hormone receptor | 0.0132 | 0.6552 | 0.6266 |
Loa Loa (eye worm) | acyltransferase | 0.0195 | 1 | 1 |
Echinococcus multilocularis | homeobox | 0.0187 | 0.9562 | 0.9561 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.1245 | 0.5 |
Echinococcus multilocularis | 1 acyl sn glycerol 3 phosphate acyltransferase | 0.0195 | 1 | 1 |
Schistosoma mansoni | 1-acyl-sn-glycerol-3-phosphate o-acyltransferase | 0.0195 | 1 | 1 |
Plasmodium falciparum | 1-acyl-sn-glycerol-3-phosphate acyltransferase, putative | 0.0195 | 1 | 0.5 |
Loa Loa (eye worm) | intermediate filament protein | 0.0026 | 0.0767 | 0.0767 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0035 | 0.1245 | 0.0518 |
Toxoplasma gondii | acyltransferase domain-containing protein | 0.0195 | 1 | 0.5 |
Echinococcus granulosus | lamin | 0.0026 | 0.0767 | 0.0742 |
Schistosoma mansoni | hypothetical protein | 0.0122 | 0.6016 | 0.5685 |
Chlamydia trachomatis | glycerol-3-phosphate acyltransferase | 0.0195 | 1 | 0.5 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0014 | 0.0102 | 0.0102 |
Echinococcus multilocularis | Phospholipid glycerol acyltransferase | 0.0195 | 1 | 1 |
Onchocerca volvulus | 0.0026 | 0.0767 | 0.5 | |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0035 | 0.1245 | 0.1222 |
Mycobacterium tuberculosis | 1-acylglycerol-3-phosphate O-acyltransferase | 0.0195 | 1 | 1 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0122 | 0.6016 | 0.6005 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.1245 | 0.5 |
Echinococcus granulosus | lamin dm0 | 0.0026 | 0.0767 | 0.0742 |
Mycobacterium ulcerans | bifunctional transmembrane phospholipid biosynthesis enzyme PlsC | 0.0195 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0026 | 0.0026 |
Mycobacterium leprae | POSSIBLE TRANSMEMBRANE PHOSPHOLIPID BIOSYNTHESIS BIFUNCTIONAL ENZYME PLSC: PUTATIVE L-3-PHOSPHOSERINE PHOSPHATASE (O-PHOSPHOSERI | 0.0195 | 1 | 0.5 |
Echinococcus granulosus | 1 acyl sn glycerol 3 phosphate acyltransferase | 0.0195 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0767 | 0.0767 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0132 | 0.6552 | 0.6543 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.1245 | 0.0518 |
Echinococcus multilocularis | lamin | 0.0026 | 0.0767 | 0.0742 |
Brugia malayi | hypothetical protein | 0.0035 | 0.1245 | 0.1154 |
Schistosoma mansoni | thyroid hormone receptor | 0.0132 | 0.6552 | 0.6266 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0026 | 0.0767 | 0.0671 |
Echinococcus granulosus | Msx-like | 0.0187 | 0.9562 | 0.9561 |
Plasmodium vivax | 1-acyl-sn-glycerol-3-phosphate acyltransferase, putative | 0.0195 | 1 | 0.5 |
Trypanosoma brucei | 1-acyl-sn-glycerol-3-phosphate acyltransferase, putative | 0.0195 | 1 | 0.5 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0026 | 0.0767 | 0.0767 |
Echinococcus granulosus | Phospholipid glycerol acyltransferase | 0.0195 | 1 | 1 |
Trypanosoma cruzi | 1-acyl-sn-glycerol-3-phosphate acyltransferase, putative | 0.0195 | 1 | 0.5 |
Onchocerca volvulus | 0.0026 | 0.0767 | 0.5 | |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.1245 | 0.5 |
Leishmania major | 1-acyl-sn-glycerol-3-phosphateacyltransferase-like protein, putative | 0.0195 | 1 | 0.5 |
Echinococcus multilocularis | 1 acyl sn glycerol 3 phosphate acyltransferase | 0.0195 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0035 | 0.1245 | 0.5 |
Echinococcus multilocularis | musashi | 0.0026 | 0.0767 | 0.0742 |
Schistosoma mansoni | transcription factor | 0.0187 | 0.9562 | 0.9525 |
Loa Loa (eye worm) | hypothetical protein | 0.0187 | 0.9562 | 0.9562 |
Echinococcus granulosus | 1 acyl sn glycerol 3 phosphate acyltransferase | 0.0195 | 1 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0035 | 0.1245 | 0.1222 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.074 | 0.074 |
Wolbachia endosymbiont of Brugia malayi | 1-acyl-sn-glycerol-3-phosphate acyltransferase | 0.0195 | 1 | 0.5 |
Echinococcus multilocularis | lamin dm0 | 0.0026 | 0.0767 | 0.0742 |
Treponema pallidum | lysophosphatidic acid acyltransferase | 0.0195 | 1 | 0.5 |
Echinococcus granulosus | intermediate filament protein | 0.0026 | 0.0767 | 0.0742 |
Mycobacterium ulcerans | 1-acylglycerol-3-phosphate O-acyltransferase | 0.0195 | 1 | 0.5 |
Toxoplasma gondii | acyltransferase domain-containing protein | 0.0195 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0195 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.