Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | glycogen phosphorylase GlgP | 0.1109 | 0.4278 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.002 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.1109 | 0.4278 | 1 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.002 | 0 | 0.5 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.2564 | 1 | 1 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.2564 | 1 | 0.5 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0 | 0.5 |
Entamoeba histolytica | glycogenphosphorylase, putative | 0.1109 | 0.4278 | 0.4278 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.1109 | 0.4278 | 0.4278 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.2564 | 1 | 1 |
Echinococcus multilocularis | glycogen phosphorylase | 0.2564 | 1 | 1 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.002 | 0 | 0.5 |
Giardia lamblia | Glycogen phosphorylase | 0.2564 | 1 | 1 |
Echinococcus granulosus | glycogen phosphorylase | 0.2564 | 1 | 1 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.002 | 0 | 0.5 |
Chlamydia trachomatis | glycogen phosphorylase | 0.2564 | 1 | 0.5 |
Toxoplasma gondii | exonuclease III APE | 0.002 | 0 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.2564 | 1 | 1 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.2564 | 1 | 1 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.2564 | 1 | 1 |
Echinococcus multilocularis | glycogen phosphorylase | 0.2564 | 1 | 1 |
Schistosoma mansoni | glycogen phosphorylase | 0.1109 | 0.4278 | 0.4278 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0 | 0.5 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.2564 | 1 | 1 |
Schistosoma mansoni | glycogen phosphorylase | 0.2564 | 1 | 1 |
Echinococcus granulosus | glycogen phosphorylase | 0.2564 | 1 | 1 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.2564 | 1 | 1 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.2564 | 1 | 1 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.1109 | 0.4278 | 0.4278 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.