Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0333 | 0.1256 | 0.259 |
Mycobacterium ulcerans | hypothetical protein | 0.0852 | 0.4243 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0355 | 0.138 | 0.2767 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0333 | 0.1256 | 0.1256 |
Echinococcus multilocularis | histone deacetylase 6 | 0.072 | 0.3486 | 0.3486 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0333 | 0.1256 | 0.2515 |
Echinococcus granulosus | g protein coupled receptor | 0.0333 | 0.1256 | 0.1256 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.072 | 0.3486 | 0.8065 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0333 | 0.1256 | 0.1256 |
Loa Loa (eye worm) | integrin alpha pat-2 | 0.0231 | 0.0668 | 0.1322 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0333 | 0.1256 | 0.259 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Echinococcus multilocularis | histone deacetylase 1 | 0.0857 | 0.4274 | 0.4274 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0333 | 0.1256 | 0.259 |
Loa Loa (eye worm) | hypothetical protein | 0.0323 | 0.1199 | 0.2399 |
Toxoplasma gondii | histone deacetylase HDAC3 | 0.0857 | 0.4274 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.0333 | 0.1256 | 0.259 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0857 | 0.4274 | 1 |
Loa Loa (eye worm) | histone deacetylase 11 | 0.0397 | 0.1626 | 0.3267 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0333 | 0.1256 | 0.2223 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0333 | 0.1256 | 0.259 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0333 | 0.1256 | 0.1256 |
Echinococcus granulosus | g-protein coupled receptor | 0.0333 | 0.1256 | 0.1256 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0857 | 0.4274 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0333 | 0.1256 | 0.259 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.072 | 0.3486 | 0.7023 |
Echinococcus granulosus | g protein coupled receptor | 0.0333 | 0.1256 | 0.1256 |
Schistosoma mansoni | hypothetical protein | 0.0333 | 0.1256 | 0.259 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0333 | 0.1256 | 0.259 |
Schistosoma mansoni | neuropeptide receptor | 0.0333 | 0.1256 | 0.259 |
Echinococcus granulosus | neuropeptide receptor | 0.0333 | 0.1256 | 0.1256 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Echinococcus multilocularis | fmrfamide receptor | 0.0333 | 0.1256 | 0.1256 |
Schistosoma mansoni | myosin xvIII | 0.0333 | 0.1256 | 0.259 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0333 | 0.1256 | 0.1256 |
Schistosoma mansoni | amine GPCR | 0.0333 | 0.1256 | 0.259 |
Echinococcus granulosus | fmrfamide receptor | 0.0333 | 0.1256 | 0.1256 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0333 | 0.1256 | 0.1256 |
Schistosoma mansoni | amine GPCR | 0.0333 | 0.1256 | 0.259 |
Schistosoma mansoni | histamine h1 receptor | 0.0333 | 0.1256 | 0.259 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0333 | 0.1256 | 0.259 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0333 | 0.1256 | 0.259 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0333 | 0.1256 | 0.259 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0333 | 0.1256 | 0.1256 |
Mycobacterium tuberculosis | Conserved protein | 0.0852 | 0.4243 | 0.5 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0333 | 0.1256 | 0.2515 |
Echinococcus multilocularis | allatostatin A receptor | 0.0333 | 0.1256 | 0.1256 |
Toxoplasma gondii | histone deacetylase HDAC2 | 0.0857 | 0.4274 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0857 | 0.4274 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0333 | 0.1256 | 0.1256 |
Trypanosoma cruzi | histone deacetylase 1, putative | 0.0857 | 0.4274 | 1 |
Brugia malayi | Dopamine receptor | 0.0333 | 0.1256 | 0.2223 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0333 | 0.1256 | 0.2223 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0333 | 0.1256 | 0.259 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0333 | 0.1256 | 0.1256 |
Echinococcus multilocularis | g protein coupled receptor | 0.0333 | 0.1256 | 0.1256 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0333 | 0.1256 | 0.1256 |
Schistosoma mansoni | biogenic amine receptor | 0.0333 | 0.1256 | 0.259 |
Brugia malayi | Dopamine receptor protein 2 | 0.0333 | 0.1256 | 0.2223 |
Echinococcus granulosus | g protein coupled receptor | 0.0333 | 0.1256 | 0.1256 |
Brugia malayi | hypothetical protein | 0.0333 | 0.1256 | 0.2223 |
Brugia malayi | hypothetical protein | 0.0333 | 0.1256 | 0.2223 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0333 | 0.1256 | 0.1256 |
Brugia malayi | RE15519p | 0.0333 | 0.1256 | 0.2223 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0333 | 0.1256 | 0.2515 |
Schistosoma mansoni | neuropeptide receptor | 0.0333 | 0.1256 | 0.259 |
Trypanosoma brucei | histone deacetylase 1 | 0.0857 | 0.4274 | 1 |
Leishmania major | histone deacetylase, putative | 0.0857 | 0.4274 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0333 | 0.1256 | 0.1256 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0333 | 0.1256 | 0.259 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.072 | 0.3486 | 0.8065 |
Echinococcus multilocularis | histone deacetylase 8 | 0.0397 | 0.1626 | 0.1626 |
Loa Loa (eye worm) | hypothetical protein | 0.0857 | 0.4274 | 0.8638 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0333 | 0.1256 | 0.1256 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0333 | 0.1256 | 0.1256 |
Plasmodium vivax | histone deacetylase 1, putative | 0.0857 | 0.4274 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0333 | 0.1256 | 0.259 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0333 | 0.1256 | 0.1256 |
Schistosoma mansoni | hypothetical protein | 0.0333 | 0.1256 | 0.259 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0857 | 0.4274 | 0.5 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0333 | 0.1256 | 0.1256 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0333 | 0.1256 | 0.1256 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0333 | 0.1256 | 0.1256 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0333 | 0.1256 | 0.1256 |
Echinococcus granulosus | neuropeptide receptor | 0.0333 | 0.1256 | 0.1256 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0333 | 0.1256 | 0.1256 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0333 | 0.1256 | 0.259 |
Echinococcus multilocularis | histone deacetylase | 0.072 | 0.3486 | 0.3486 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Brugia malayi | AKH receptor | 0.0333 | 0.1256 | 0.2223 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0333 | 0.1256 | 0.1256 |
Brugia malayi | ORL1-like opioid receptor | 0.0333 | 0.1256 | 0.2223 |
Plasmodium vivax | histone deacetylase, putative | 0.072 | 0.3486 | 0.7023 |
Schistosoma mansoni | adenoreceptor | 0.0333 | 0.1256 | 0.259 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0333 | 0.1256 | 0.1256 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0333 | 0.1256 | 0.2223 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0333 | 0.1256 | 0.259 |
Brugia malayi | histone deacetylase 3 (HD3) | 0.0857 | 0.4274 | 0.8585 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Echinococcus granulosus | nuclear receptor co repressor related ncor | 0.0544 | 0.2472 | 0.2472 |
Echinococcus granulosus | neuropeptide s receptor | 0.0333 | 0.1256 | 0.1256 |
Brugia malayi | larval opioid receptor | 0.0333 | 0.1256 | 0.2223 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0333 | 0.1256 | 0.2515 |
Echinococcus multilocularis | serotonin receptor | 0.0333 | 0.1256 | 0.1256 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0333 | 0.1256 | 0.1256 |
Loa Loa (eye worm) | hypothetical protein | 0.0397 | 0.1626 | 0.3267 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0857 | 0.4274 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Brugia malayi | Histone deacetylase 1 | 0.0857 | 0.4274 | 0.8585 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0333 | 0.1256 | 0.1256 |
Brugia malayi | Histone deacetylase family protein | 0.072 | 0.3486 | 0.6923 |
Echinococcus granulosus | histone deacetylase 6 | 0.072 | 0.3486 | 0.3486 |
Echinococcus multilocularis | sex peptide receptor | 0.0333 | 0.1256 | 0.1256 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0333 | 0.1256 | 0.2223 |
Brugia malayi | Histone deacetylase family protein | 0.072 | 0.3486 | 0.6923 |
Echinococcus granulosus | histone deacetylase 3 | 0.0857 | 0.4274 | 0.4274 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0333 | 0.1256 | 0.1256 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0857 | 0.4274 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Echinococcus granulosus | allatostatin A receptor | 0.0333 | 0.1256 | 0.1256 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0397 | 0.1626 | 0.35 |
Echinococcus multilocularis | histone deacetylase 3 | 0.0857 | 0.4274 | 0.4274 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0333 | 0.1256 | 0.1256 |
Brugia malayi | neuropeptide F receptor | 0.0333 | 0.1256 | 0.2223 |
Brugia malayi | histone deacetylase 11 | 0.0397 | 0.1626 | 0.3004 |
Echinococcus multilocularis | g protein coupled receptor | 0.0333 | 0.1256 | 0.1256 |
Schistosoma mansoni | histone deacetylase | 0.0857 | 0.4274 | 1 |
Brugia malayi | follicle stimulating hormone receptor | 0.0333 | 0.1256 | 0.2223 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0333 | 0.1256 | 0.259 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0333 | 0.1256 | 0.1256 |
Echinococcus granulosus | histone deacetylase 6 | 0.072 | 0.3486 | 0.3486 |
Schistosoma mansoni | histone deacetylase 1 2 3 | 0.0397 | 0.1626 | 0.35 |
Brugia malayi | hypothetical protein | 0.0333 | 0.1256 | 0.2223 |
Brugia malayi | Serotonin receptor | 0.0333 | 0.1256 | 0.2223 |
Echinococcus multilocularis | nuclear receptor co repressor related (ncor) | 0.0544 | 0.2472 | 0.2472 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0333 | 0.1256 | 0.1256 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0333 | 0.1256 | 0.1256 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0333 | 0.1256 | 0.259 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0333 | 0.1256 | 0.2223 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0333 | 0.1256 | 0.1256 |
Schistosoma mansoni | histone deacetylase | 0.0857 | 0.4274 | 1 |
Trypanosoma brucei | histone deacetylase 4 | 0.072 | 0.3486 | 0.7023 |
Echinococcus multilocularis | serotonin receptor | 0.0333 | 0.1256 | 0.1256 |
Schistosoma mansoni | amine GPCR | 0.0333 | 0.1256 | 0.259 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0333 | 0.1256 | 0.1256 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0333 | 0.1256 | 0.1256 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Echinococcus granulosus | histone deacetylase 6 | 0.0752 | 0.3667 | 0.3667 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0333 | 0.1256 | 0.259 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0333 | 0.1256 | 0.259 |
Onchocerca volvulus | Histone deacetylase 10 homolog | 0.0397 | 0.1626 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0333 | 0.1256 | 0.1256 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0333 | 0.1256 | 0.1256 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0333 | 0.1256 | 0.1256 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Echinococcus multilocularis | fmrfamide receptor | 0.0333 | 0.1256 | 0.1256 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Echinococcus granulosus | histone deacetylase 8 | 0.0397 | 0.1626 | 0.1626 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0333 | 0.1256 | 0.1256 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.072 | 0.3486 | 0.7039 |
Entamoeba histolytica | histone deacetylase, putative | 0.0857 | 0.4274 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0333 | 0.1256 | 0.2515 |
Brugia malayi | hypothetical protein | 0.0333 | 0.1256 | 0.2223 |
Brugia malayi | Serotonin receptor | 0.0333 | 0.1256 | 0.2223 |
Schistosoma mansoni | amine GPCR | 0.0333 | 0.1256 | 0.259 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0333 | 0.1256 | 0.1256 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0852 | 0.4243 | 0.5 |
Schistosoma mansoni | neuropeptide receptor | 0.0333 | 0.1256 | 0.259 |
Loa Loa (eye worm) | histone deacetylase 1 | 0.0857 | 0.4274 | 0.8638 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0333 | 0.1256 | 0.2223 |
Echinococcus granulosus | histone deacetylase 7 | 0.072 | 0.3486 | 0.3486 |
Brugia malayi | G-protein coupled receptor | 0.0333 | 0.1256 | 0.2223 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0333 | 0.1256 | 0.1256 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0333 | 0.1256 | 0.1256 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0333 | 0.1256 | 0.259 |
Brugia malayi | Dopamine receptor protein 1 | 0.0333 | 0.1256 | 0.2223 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0333 | 0.1256 | 0.259 |
Plasmodium falciparum | histone deacetylase 1 | 0.0857 | 0.4274 | 1 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0333 | 0.1256 | 0.2515 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0333 | 0.1256 | 0.1256 |
Echinococcus granulosus | histone deacetylase | 0.072 | 0.3486 | 0.3486 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Schistosoma mansoni | opsin-like receptor | 0.0333 | 0.1256 | 0.259 |
Loa Loa (eye worm) | histone deacetylase 3 | 0.0857 | 0.4274 | 0.8638 |
Leishmania major | histone deacetylase, putative | 0.0857 | 0.4274 | 1 |
Trypanosoma brucei | histone deacetylase, putative | 0.072 | 0.3486 | 0.7023 |
Echinococcus multilocularis | histone deacetylase 7 | 0.072 | 0.3486 | 0.3486 |
Brugia malayi | G protein-coupled receptor | 0.0333 | 0.1256 | 0.2223 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0333 | 0.1256 | 0.1256 |
Echinococcus multilocularis | histone deacetylase 6 | 0.072 | 0.3486 | 0.3486 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0333 | 0.1256 | 0.1256 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0333 | 0.1256 | 0.1256 |
Brugia malayi | hypothetical protein | 0.0974 | 0.4945 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0857 | 0.4274 | 0.5 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0333 | 0.1256 | 0.1256 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0333 | 0.1256 | 0.1256 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0333 | 0.1256 | 0.1256 |
Brugia malayi | neuropeptide F receptor | 0.0333 | 0.1256 | 0.2223 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0333 | 0.1256 | 0.1256 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Loa Loa (eye worm) | hypothetical protein | 0.0974 | 0.4945 | 1 |
Giardia lamblia | Histone deacetylase | 0.0857 | 0.4274 | 0.5 |
Echinococcus multilocularis | somatostatin receptor | 0.0333 | 0.1256 | 0.1256 |
Mycobacterium leprae | conserved hypothetical protein | 0.0852 | 0.4243 | 0.5 |
Brugia malayi | hypothetical protein | 0.0333 | 0.1256 | 0.2223 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0333 | 0.1256 | 0.259 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0333 | 0.1256 | 0.2223 |
Trypanosoma cruzi | histone deacetylase, putative | 0.072 | 0.3486 | 0.7023 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0333 | 0.1256 | 0.1256 |
Echinococcus granulosus | orexin receptor type 2 | 0.0333 | 0.1256 | 0.1256 |
Loa Loa (eye worm) | histone deacetylase | 0.072 | 0.3486 | 0.7039 |
Echinococcus granulosus | somatostatin receptor | 0.0333 | 0.1256 | 0.1256 |
Brugia malayi | GnHR receptor homolog | 0.0837 | 0.4155 | 0.8335 |
Echinococcus multilocularis | neuropeptide receptor | 0.0333 | 0.1256 | 0.1256 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0333 | 0.1256 | 0.1256 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0333 | 0.1256 | 0.1256 |
Brugia malayi | G-protein coupled receptor | 0.0333 | 0.1256 | 0.2223 |
Mycobacterium ulcerans | hypothetical protein | 0.0852 | 0.4243 | 0.5 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0333 | 0.1256 | 0.259 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0333 | 0.1256 | 0.1256 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0333 | 0.1256 | 0.259 |
Brugia malayi | hypothetical protein | 0.0333 | 0.1256 | 0.2223 |
Schistosoma mansoni | amine GPCR | 0.0333 | 0.1256 | 0.259 |
Trypanosoma cruzi | histone deacetylase, putative | 0.072 | 0.3486 | 0.7023 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0333 | 0.1256 | 0.1256 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0333 | 0.1256 | 0.259 |
Schistosoma mansoni | neuropeptide receptor | 0.0333 | 0.1256 | 0.259 |
Plasmodium vivax | histone deacetylase 2, putative | 0.072 | 0.3486 | 0.7023 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0752 | 0.3667 | 0.3667 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0333 | 0.1256 | 0.2515 |
Brugia malayi | sulfakinin receptor protein | 0.0974 | 0.4945 | 1 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0333 | 0.1256 | 0.1256 |
Brugia malayi | putative neuropeptide receptor | 0.0333 | 0.1256 | 0.2223 |
Trypanosoma brucei | histone deacetylase 3 | 0.072 | 0.3486 | 0.7023 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.1852 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0333 | 0.1256 | 0.259 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0333 | 0.1256 | 0.2515 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0333 | 0.1256 | 0.1256 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0857 | 0.4274 | 0.5 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0333 | 0.1256 | 0.1256 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0333 | 0.1256 | 0.2515 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0333 | 0.1256 | 0.1256 |
Echinococcus granulosus | sex peptide receptor | 0.0333 | 0.1256 | 0.1256 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0333 | 0.1256 | 0.1256 |
Brugia malayi | hypothetical protein | 0.0333 | 0.1256 | 0.2223 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Schistosoma mansoni | hypothetical protein | 0.0333 | 0.1256 | 0.259 |
Trypanosoma cruzi | histone deacetylase, putative | 0.072 | 0.3486 | 0.7023 |
Echinococcus granulosus | serotonin receptor | 0.0333 | 0.1256 | 0.1256 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0333 | 0.1256 | 0.259 |
Echinococcus granulosus | hypothetical protein | 0.0333 | 0.1256 | 0.1256 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0333 | 0.1256 | 0.2515 |
Brugia malayi | hypothetical protein | 0.0333 | 0.1256 | 0.2223 |
Schistosoma mansoni | biogenic amine receptor | 0.0333 | 0.1256 | 0.259 |
Brugia malayi | histone deacetylase 1 (HD1) | 0.0857 | 0.4274 | 0.8585 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Brugia malayi | hypothetical protein | 0.0333 | 0.1256 | 0.2223 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0333 | 0.1256 | 0.259 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0333 | 0.1256 | 0.1256 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0333 | 0.1256 | 0.1256 |
Echinococcus multilocularis | neuropeptide receptor | 0.0333 | 0.1256 | 0.1256 |
Brugia malayi | Melatonin receptor type 1A | 0.0333 | 0.1256 | 0.2223 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0333 | 0.1256 | 0.1256 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0333 | 0.1256 | 0.1256 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0333 | 0.1256 | 0.259 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0333 | 0.1256 | 0.1256 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0333 | 0.1256 | 0.259 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0752 | 0.3667 | 0.851 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0333 | 0.1256 | 0.1256 |
Loa Loa (eye worm) | hypothetical protein | 0.0333 | 0.1256 | 0.2515 |
Echinococcus granulosus | histone deacetylase 1 | 0.0857 | 0.4274 | 0.4274 |
Schistosoma mansoni | opsin-like receptor | 0.0333 | 0.1256 | 0.259 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0333 | 0.1256 | 0.259 |
Schistosoma mansoni | biogenic amine receptor | 0.0333 | 0.1256 | 0.259 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0333 | 0.1256 | 0.1256 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0857 | 0.4274 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0857 | 0.4274 | 0.5 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0333 | 0.1256 | 0.2515 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0333 | 0.1256 | 0.2223 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0333 | 0.1256 | 0.1256 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
EC50 (functional) | = 0.19 ug ml-1 | Inhibitory concentration required to inhibit HIV replication in H9 lymphocytes growth by 50% | ChEMBL. | 10021911 |
EC50 (functional) | = 0.19 ug ml-1 | Inhibitory concentration required to inhibit HIV replication in H9 lymphocytes growth by 50% | ChEMBL. | 10021911 |
IC50 (functional) | = 26 ug ml-1 | Inhibitory concentration required to inhibit uninfected H9 lymphocytic cell growth by 50% | ChEMBL. | 10021911 |
IC50 (functional) | = 26 ug ml-1 | Inhibitory concentration required to inhibit uninfected H9 lymphocytic cell growth by 50% | ChEMBL. | 10021911 |
TI (functional) | = 136 | Therapeutic index(TI) of the compound was evaluated (IC50/EC50) | ChEMBL. | 10021911 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.