Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | ctsf protein | 0.0313 | 0.3939 | 0.3938 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0313 | 0.3939 | 0.3938 |
Brugia malayi | Cathepsin L-like precursor | 0.0216 | 0.2246 | 0.2093 |
Loa Loa (eye worm) | glyceraldehyde-3-phosphate dehydrogenase | 0.0091 | 0.0082 | 0.008 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0313 | 0.3939 | 0.3939 |
Chlamydia trachomatis | glyceraldehyde-3-phosphate dehydrogenase | 0.0132 | 0.0791 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Leishmania major | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.0132 | 0.0791 | 0.2009 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.017 | 0.1455 | 0.3693 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Echinococcus granulosus | cathepsin l1 | 0.0313 | 0.3939 | 0.3938 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0662 | 1 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0098 | 0.0193 | 0.0192 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0662 | 1 | 1 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0132 | 0.0791 | 0.0791 |
Brugia malayi | Cathepsin L-like precursor | 0.0313 | 0.3939 | 0.382 |
Onchocerca volvulus | 0.0313 | 0.3939 | 1 | |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, cytosolic | 0.0132 | 0.0791 | 0.2009 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Plasmodium vivax | vivapain-2 | 0.0313 | 0.3939 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.017 | 0.1455 | 0.1455 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.2007 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.017 | 0.1455 | 0.1287 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0313 | 0.3939 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0313 | 0.3939 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0313 | 0.3939 | 0.3938 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.017 | 0.1455 | 0.1287 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.0132 | 0.0791 | 0.061 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0313 | 0.3939 | 0.3938 |
Echinococcus multilocularis | cysteine protease | 0.0313 | 0.3939 | 0.3938 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0132 | 0.0791 | 0.0791 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0662 | 1 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.017 | 0.1455 | 0.1287 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0255 | 0.2928 | 0.7434 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.0791 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Loa Loa (eye worm) | glyceraldehyde-3-phosphate dehydrogenase | 0.0091 | 0.0082 | 0.008 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.2007 |
Brugia malayi | Cathepsin L-like precursor | 0.0313 | 0.3939 | 0.382 |
Leishmania major | cathepsin L-like protease | 0.0313 | 0.3939 | 1 |
Leishmania major | cathepsin L-like protease | 0.0313 | 0.3939 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0098 | 0.0193 | 0.0193 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.2246 | 0.2245 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0098 | 0.0193 | 0.0193 |
Toxoplasma gondii | cathepsin CPL | 0.0313 | 0.3939 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.017 | 0.1455 | 0.3695 |
Brugia malayi | Glyceraldehyde 3-phosphate dehydrogenase | 0.0132 | 0.0791 | 0.061 |
Plasmodium vivax | unspecified product | 0.017 | 0.1455 | 0.3369 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0216 | 0.2246 | 0.2093 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0313 | 0.3939 | 0.3938 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Leishmania major | cathepsin L-like protease | 0.0313 | 0.3939 | 1 |
Leishmania major | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.0132 | 0.0791 | 0.2009 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0313 | 0.3939 | 0.3938 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0193 | 0.0192 |
Entamoeba histolytica | cysteine proteinase, putative | 0.017 | 0.1455 | 0.2109 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0193 | 0.0192 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.0193 | 0.0192 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.0132 | 0.0791 | 0.079 |
Wolbachia endosymbiont of Brugia malayi | glyceraldehyde-3-phosphate dehydrogenase, GapA | 0.0132 | 0.0791 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.0132 | 0.0791 | 0.079 |
Onchocerca volvulus | 0.0313 | 0.3939 | 1 | |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0313 | 0.3939 | 0.382 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0313 | 0.3939 | 0.3938 |
Loa Loa (eye worm) | hypothetical protein | 0.0313 | 0.3939 | 0.3938 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0216 | 0.2246 | 0.2093 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Plasmodium vivax | glyceraldehyde-3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.1597 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.0132 | 0.0791 | 0.061 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0313 | 0.3939 | 0.3939 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0313 | 0.3939 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0662 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0313 | 0.3939 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0662 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.2246 | 0.2245 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.0791 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0255 | 0.2928 | 0.2928 |
Brugia malayi | Cathepsin L-like precursor | 0.0313 | 0.3939 | 0.382 |
Leishmania major | cathepsin L-like protease | 0.0313 | 0.3939 | 1 |
Echinococcus multilocularis | glyceraldehyde 3 phosphate dehydrogenase | 0.0132 | 0.0791 | 0.079 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0313 | 0.3939 | 0.3939 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.0132 | 0.0791 | 0.061 |
Echinococcus granulosus | cathepsin L | 0.017 | 0.1455 | 0.1454 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0313 | 0.3939 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Onchocerca volvulus | 0.0313 | 0.3939 | 1 | |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.017 | 0.1455 | 0.2109 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0216 | 0.2246 | 0.2093 |
Onchocerca volvulus | 0.0313 | 0.3939 | 1 | |
Trypanosoma cruzi | cysteine protease, putative | 0.017 | 0.1455 | 0.1455 |
Echinococcus granulosus | cathepsin b | 0.0662 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0313 | 0.3939 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0313 | 0.3939 | 0.382 |
Entamoeba histolytica | cysteine proteinase, putative | 0.017 | 0.1455 | 0.2109 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0216 | 0.2246 | 0.2093 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0313 | 0.3939 | 0.382 |
Treponema pallidum | glyceraldehyde 3-phosphate dehydrogenase (gap) | 0.0132 | 0.0791 | 0.5 |
Toxoplasma gondii | cathepsin B | 0.0255 | 0.2928 | 0.6788 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.017 | 0.1455 | 0.1455 |
Onchocerca volvulus | Cathepsin L homolog | 0.0313 | 0.3939 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0216 | 0.2246 | 0.2246 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0255 | 0.2928 | 0.2789 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0313 | 0.3939 | 1 |
Echinococcus multilocularis | cathepsin L | 0.017 | 0.1455 | 0.1454 |
Onchocerca volvulus | Cathepsin L homolog | 0.0313 | 0.3939 | 1 |
Giardia lamblia | Glyceraldehyde 3-phosphate dehydrogenase | 0.0132 | 0.0791 | 0.2703 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.2007 |
Giardia lamblia | Cathepsin B precursor | 0.0255 | 0.2928 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0216 | 0.2246 | 0.2245 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.0132 | 0.0791 | 0.2009 |
Plasmodium vivax | vivapain-1 | 0.017 | 0.1455 | 0.3369 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0216 | 0.2246 | 0.5699 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.0791 |
Giardia lamblia | Cathepsin B precursor | 0.0255 | 0.2928 | 1 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.2007 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0313 | 0.3939 | 0.3939 |
Brugia malayi | Papain family cysteine protease containing protein | 0.017 | 0.1455 | 0.1287 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0313 | 0.3939 | 0.382 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0255 | 0.2928 | 0.7434 |
Entamoeba histolytica | cysteine proteinase 2 | 0.017 | 0.1455 | 0.2109 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.017 | 0.1455 | 0.3695 |
Leishmania major | cysteine peptidase A (CPA) | 0.0313 | 0.3939 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.017 | 0.1455 | 0.2109 |
Entamoeba histolytica | cysteine proteinase, putative | 0.017 | 0.1455 | 0.2109 |
Echinococcus granulosus | glyceraldehyde 3 phosphate dehydrogenase | 0.0132 | 0.0791 | 0.079 |
Plasmodium vivax | vivapain-2 | 0.0313 | 0.3939 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0255 | 0.2928 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0313 | 0.3939 | 0.3938 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0313 | 0.3939 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0313 | 0.3939 | 0.3938 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.017 | 0.1455 | 0.1455 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.017 | 0.1455 | 0.1287 |
Onchocerca volvulus | 0.0313 | 0.3939 | 1 | |
Echinococcus granulosus | cathepsin l1 | 0.0216 | 0.2246 | 0.2245 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative | 0.0132 | 0.0791 | 0.0791 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0313 | 0.3939 | 0.3938 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0255 | 0.2928 | 0.7433 |
Onchocerca volvulus | 0.0313 | 0.3939 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Trypanosoma brucei | glyceraldehyde 3-phosphate dehydrogenase, glycosomal | 0.0132 | 0.0791 | 0.2009 |
Echinococcus granulosus | cathepsin b | 0.0662 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0662 | 1 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0313 | 0.3939 | 0.3938 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Schistosoma mansoni | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) | 0.0132 | 0.0791 | 0.061 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0216 | 0.2246 | 0.462 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0313 | 0.3939 | 0.3939 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.017 | 0.1455 | 0.3693 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0662 | 1 | 1 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.017 | 0.1455 | 0.1454 |
Echinococcus granulosus | cysteine protease | 0.017 | 0.1455 | 0.1454 |
Leishmania major | cathepsin L-like protease | 0.0313 | 0.3939 | 1 |
Plasmodium vivax | vivapain-3 | 0.017 | 0.1455 | 0.3369 |
Mycobacterium ulcerans | glyceraldehyde 3-phosphate dehydrogenase Gap | 0.0132 | 0.0791 | 0.5 |
Trichomonas vaginalis | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.2007 |
Loa Loa (eye worm) | cysteine protease | 0.0313 | 0.3939 | 0.3938 |
Trypanosoma cruzi | glyceraldehyde 3-phosphate dehydrogenase, putative | 0.0132 | 0.0791 | 0.0791 |
Brugia malayi | Cathepsin L-like precursor | 0.0313 | 0.3939 | 0.382 |
Echinococcus multilocularis | cathepsin b | 0.0662 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.017 | 0.1455 | 0.1455 |
Entamoeba histolytica | cysteine proteinase, putative | 0.017 | 0.1455 | 0.2109 |
Leishmania major | cathepsin L-like protease | 0.0313 | 0.3939 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0313 | 0.3939 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Leishmania major | cathepsin L-like protease | 0.0313 | 0.3939 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0313 | 0.3939 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0216 | 0.2246 | 0.5699 |
Loa Loa (eye worm) | cathepsin B | 0.0255 | 0.2928 | 0.2927 |
Onchocerca volvulus | 0.0313 | 0.3939 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0313 | 0.3939 | 0.382 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.017 | 0.1455 | 0.2109 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ILS (functional) | = 0 % | Percent increase in median life span of BDF1 mice with P-388 leukemia at dose 200 mg/kg administered intraperitoneally | ChEMBL. | 6806475 |
ILS (functional) | = 0 % | Percent increase in median life span of BDF1 mice with B-16 melanoma at dose 50 mg/kg administered intraperitoneally | ChEMBL. | 6806475 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.