Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0071 | 0.3757 | 1 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1812 | 0.1812 |
Echinococcus multilocularis | cysteine protease | 0.0071 | 0.3757 | 0.3892 |
Echinococcus granulosus | cathepsin b | 0.015 | 0.9653 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0039 | 0.1321 | 0.3517 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0071 | 0.3757 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0071 | 0.3757 | 1 |
Brugia malayi | RNase H family protein | 0.0041 | 0.1511 | 0.1565 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.1812 | 0.1877 |
Entamoeba histolytica | cysteine protease, putative | 0.0071 | 0.3757 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.3757 | 0.3757 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0071 | 0.3757 | 0.3892 |
Echinococcus granulosus | cathepsin l1 | 0.0071 | 0.3757 | 0.3892 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0071 | 0.3757 | 0.3892 |
Brugia malayi | Cathepsin L-like precursor | 0.0071 | 0.3757 | 0.3892 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1812 | 0.1812 |
Brugia malayi | Cathepsin L-like precursor | 0.0071 | 0.3757 | 0.3892 |
Entamoeba histolytica | cysteine protease, putative | 0.0039 | 0.1321 | 0.3517 |
Toxoplasma gondii | cathepsin CPL | 0.0071 | 0.3757 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0022 | 0.0085 | 0.0088 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0071 | 0.3757 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0071 | 0.3757 | 1 |
Onchocerca volvulus | 0.0049 | 0.2096 | 0.2606 | |
Leishmania major | cathepsin L-like protease | 0.0071 | 0.3757 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0039 | 0.1321 | 0.1369 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0071 | 0.3757 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0022 | 0.0085 | 0.0088 |
Onchocerca volvulus | 0.0071 | 0.3757 | 1 | |
Entamoeba histolytica | cysteine proteinase 2 | 0.0039 | 0.1321 | 0.3517 |
Echinococcus multilocularis | cathepsin b | 0.015 | 0.9653 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.9653 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0039 | 0.1321 | 0.3517 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.3757 | 0.3757 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0071 | 0.3757 | 1 |
Trypanosoma brucei | ribonuclease H1 | 0.0041 | 0.1511 | 0.1511 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0049 | 0.2096 | 0.5579 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0049 | 0.2096 | 0.5579 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.3757 | 0.3757 |
Brugia malayi | RNase H family protein | 0.0041 | 0.1511 | 0.1565 |
Entamoeba histolytica | cysteine protease, putative | 0.0039 | 0.1321 | 0.3517 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0071 | 0.3757 | 1 |
Toxoplasma gondii | ribonuclease HI protein | 0.0041 | 0.1511 | 0.4021 |
Treponema pallidum | ribonuclease H (rnhA) | 0.0041 | 0.1511 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0039 | 0.1321 | 0.3517 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0071 | 0.3757 | 0.3892 |
Echinococcus granulosus | cathepsin b | 0.015 | 0.9653 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0071 | 0.3757 | 1 |
Plasmodium vivax | vivapain-1 | 0.0039 | 0.1321 | 0.3517 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0071 | 0.3757 | 1 |
Toxoplasma gondii | cathepsin B | 0.0058 | 0.2751 | 0.7321 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0071 | 0.3757 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0071 | 0.3757 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0039 | 0.1321 | 0.3517 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0058 | 0.2751 | 0.2751 |
Trypanosoma cruzi | ribonuclease H1, putative | 0.0041 | 0.1511 | 0.1565 |
Trypanosoma brucei | RNA helicase, putative | 0.0155 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0039 | 0.1321 | 0.3517 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.3757 | 0.3757 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.015 | 0.9653 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0071 | 0.3757 | 0.3892 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0039 | 0.1321 | 0.1369 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0071 | 0.3757 | 0.3892 |
Plasmodium vivax | unspecified product | 0.0022 | 0.0085 | 0.0226 |
Echinococcus granulosus | ribonuclease H1 | 0.0041 | 0.1511 | 0.1565 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0039 | 0.1321 | 0.1369 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0068 | 0.3512 | 0.9347 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0071 | 0.3757 | 1 |
Leishmania major | cathepsin L-like protease | 0.0071 | 0.3757 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.3757 | 0.3892 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0071 | 0.3757 | 0.3892 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0049 | 0.2096 | 0.2096 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0071 | 0.3757 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0039 | 0.1321 | 0.1369 |
Brugia malayi | Cathepsin L-like precursor | 0.0049 | 0.2096 | 0.2172 |
Echinococcus multilocularis | cathepsin L | 0.0039 | 0.1321 | 0.1369 |
Entamoeba histolytica | cysteine protease, putative | 0.0039 | 0.1321 | 0.3517 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0022 | 0.0085 | 0.0088 |
Plasmodium vivax | unspecified product | 0.0039 | 0.1321 | 0.3517 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0039 | 0.1321 | 0.1321 |
Schistosoma mansoni | cathepsin s | 0.0022 | 0.0085 | 0.0085 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0039 | 0.1321 | 0.1321 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0071 | 0.3757 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0039 | 0.1321 | 0.3517 |
Brugia malayi | cathepsin L-like precursor | 0.0049 | 0.2096 | 0.2172 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0071 | 0.3757 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0039 | 0.1321 | 0.3517 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.3757 | 0.3757 |
Schistosoma mansoni | phosphoglucomutase | 0.0041 | 0.1511 | 0.1511 |
Onchocerca volvulus | 0.0071 | 0.3757 | 1 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0071 | 0.3757 | 1 |
Plasmodium vivax | vivapain-2 | 0.0071 | 0.3757 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0071 | 0.3757 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0049 | 0.2096 | 0.2172 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0039 | 0.1321 | 0.1369 |
Echinococcus granulosus | cathepsin l1 | 0.0049 | 0.2096 | 0.2172 |
Trypanosoma brucei | ingi protein (ORF1) | 0.0045 | 0.1773 | 0.1773 |
Brugia malayi | Cathepsin L-like precursor | 0.0071 | 0.3757 | 0.3892 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0039 | 0.1321 | 0.3517 |
Giardia lamblia | Cathepsin B precursor | 0.0058 | 0.2751 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.3757 | 0.3757 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0039 | 0.1321 | 0.1321 |
Onchocerca volvulus | 0.0071 | 0.3757 | 1 | |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0071 | 0.3757 | 0.3892 |
Entamoeba histolytica | cysteine protease, putative | 0.0039 | 0.1321 | 0.3517 |
Plasmodium vivax | vivapain-3 | 0.0039 | 0.1321 | 0.3517 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.3757 | 0.3757 |
Entamoeba histolytica | cysteine protease, putative | 0.0039 | 0.1321 | 0.3517 |
Schistosoma mansoni | phosphoglucomutase | 0.0041 | 0.1511 | 0.1511 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.3757 | 0.3757 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0049 | 0.2096 | 0.2172 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.2096 | 0.2172 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0068 | 0.3512 | 1 |
Brugia malayi | RNase H family protein | 0.0041 | 0.1511 | 0.1565 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.3757 | 0.3757 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0071 | 0.3757 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0049 | 0.2096 | 0.2172 |
Onchocerca volvulus | Cathepsin L homolog | 0.0071 | 0.3757 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0071 | 0.3757 | 0.3892 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0068 | 0.3512 | 0.3512 |
Schistosoma mansoni | phosphoglucomutase | 0.0041 | 0.1511 | 0.1511 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0039 | 0.1321 | 0.3517 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0022 | 0.0085 | 0.0088 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0058 | 0.2751 | 0.285 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.2096 | 0.2172 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0068 | 0.3512 | 0.9347 |
Entamoeba histolytica | cysteine protease, putative | 0.0039 | 0.1321 | 0.3517 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0058 | 0.2751 | 0.7321 |
Entamoeba histolytica | cysteine protease, putative | 0.0039 | 0.1321 | 0.3517 |
Brugia malayi | Cathepsin L-like precursor | 0.0071 | 0.3757 | 0.3892 |
Entamoeba histolytica | cysteine protease, putative | 0.0039 | 0.1321 | 0.3517 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0071 | 0.3757 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.1812 | 0.1877 |
Leishmania major | cathepsin L-like protease | 0.0071 | 0.3757 | 1 |
Onchocerca volvulus | 0.0071 | 0.3757 | 1 | |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0068 | 0.3512 | 0.3512 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0058 | 0.2751 | 0.7321 |
Wolbachia endosymbiont of Brugia malayi | ribonuclease HI | 0.0041 | 0.1511 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0071 | 0.3757 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.1812 | 0.1877 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0022 | 0.0085 | 0.0088 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0068 | 0.3512 | 0.3638 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0071 | 0.3757 | 1 |
Echinococcus granulosus | cysteine protease | 0.0039 | 0.1321 | 0.1369 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0071 | 0.3757 | 0.3757 |
Giardia lamblia | Cathepsin B precursor | 0.0058 | 0.2751 | 1 |
Leishmania major | cathepsin L-like protease | 0.0071 | 0.3757 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0039 | 0.1321 | 0.1321 |
Trichomonas vaginalis | ribonuclease H1, putative | 0.0041 | 0.1511 | 0.4021 |
Brugia malayi | Cathepsin L-like precursor | 0.0071 | 0.3757 | 0.3892 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0071 | 0.3757 | 0.3892 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.015 | 0.9653 | 0.9653 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.1812 | 0.1877 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0071 | 0.3757 | 0.3757 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0068 | 0.3512 | 1 |
Trypanosoma brucei | retrotransposon hot spot protein 4 (RHS4), interrupted | 0.0045 | 0.1773 | 0.1773 |
Leishmania major | cathepsin L-like protease | 0.0071 | 0.3757 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0071 | 0.3757 | 0.3892 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0045 | 0.1773 | 0.1773 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0071 | 0.3757 | 0.3892 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0071 | 0.3757 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0039 | 0.1321 | 0.3517 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0039 | 0.1321 | 0.1369 |
Onchocerca volvulus | 0.0071 | 0.3757 | 1 | |
Leishmania major | cathepsin L-like protease | 0.0071 | 0.3757 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0071 | 0.3757 | 1 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0068 | 0.3512 | 0.3638 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0071 | 0.3757 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.1812 | 0.1812 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0071 | 0.3757 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0071 | 0.3757 | 0.3892 |
Giardia lamblia | Cathepsin B precursor | 0.0058 | 0.2751 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0071 | 0.3757 | 0.3892 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.3757 | 0.3757 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0071 | 0.3757 | 1 |
Onchocerca volvulus | 0.0071 | 0.3757 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0071 | 0.3757 | 0.3757 |
Trypanosoma brucei | unspecified product | 0.0045 | 0.1773 | 0.1773 |
Leishmania major | ribonuclease H1, putative | 0.0041 | 0.1511 | 0.4021 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.015 | 0.9653 | 0.9653 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0071 | 0.3757 | 0.3892 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0039 | 0.1321 | 0.3517 |
Echinococcus granulosus | cathepsin L | 0.0039 | 0.1321 | 0.1369 |
Leishmania major | cysteine peptidase A (CPA) | 0.0071 | 0.3757 | 1 |
Trypanosoma cruzi | cysteine protease, putative | 0.0039 | 0.1321 | 0.1369 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0071 | 0.3757 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.1812 | 0.1877 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.1812 | 0.1877 |
Trypanosoma brucei | ingi protein (ORF1) | 0.0045 | 0.1773 | 0.1773 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.015 | 0.9653 | 0.9653 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.2096 | 0.2172 |
Onchocerca volvulus | Cathepsin L homolog | 0.0071 | 0.3757 | 1 |
Plasmodium vivax | vivapain-2 | 0.0071 | 0.3757 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0039 | 0.1321 | 0.1321 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0085 | 0.0088 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0058 | 0.2751 | 0.2751 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0022 | 0.0085 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0085 | 0.0088 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0039 | 0.1321 | 0.1369 |
Echinococcus multilocularis | cysteine protease | 0.0071 | 0.3757 | 0.3892 |
Leishmania major | cathepsin L-like protease | 0.0071 | 0.3757 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.015 | 0.9653 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.015 | 0.9653 | 0.9653 |
Trypanosoma cruzi | ribonuclease H1, putative | 0.0041 | 0.1511 | 0.1565 |
Echinococcus multilocularis | cathepsin b | 0.015 | 0.9653 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0085 | 0.0088 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0068 | 0.3512 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0071 | 0.3757 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0071 | 0.3757 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0039 | 0.1321 | 0.3517 |
Loa Loa (eye worm) | cathepsin B | 0.0058 | 0.2751 | 0.285 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0071 | 0.3757 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0049 | 0.2096 | 0.5579 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0071 | 0.3757 | 0.3892 |
Echinococcus multilocularis | ribonuclease H1 | 0.0041 | 0.1511 | 0.1565 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0071 | 0.3757 | 0.3892 |
Loa Loa (eye worm) | cysteine protease | 0.0071 | 0.3757 | 0.3892 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0071 | 0.3757 | 1 |
Leishmania major | cathepsin L-like protease | 0.0071 | 0.3757 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0068 | 0.3512 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0039 | 0.1321 | 0.3517 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0071 | 0.3757 | 0.3892 |
Giardia lamblia | Ribonuclease H | 0.0041 | 0.1511 | 0.5493 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
EC50 (functional) | = 51.8 uM | Effective concentration of the compound against HIV-1RF induced cytopathicity in CEM-SS cells | ChEMBL. | 8558520 |
EC50 (functional) | = 51.8 uM | Effective concentration of the compound against HIV-1RF induced cytopathicity in CEM-SS cells | ChEMBL. | 8558520 |
IC50 (functional) | = 86 uM | Cytotoxic concentration of the compound against mock-infected CEM-SS cells | ChEMBL. | 8558520 |
IC50 (functional) | = 86 uM | Cytotoxic concentration of the compound against mock-infected CEM-SS cells | ChEMBL. | 8558520 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.