Detailed information for compound 260053

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 295.294 | Formula: C12H17N5O4
  • H donors: 4 H acceptors: 6 LogP: -1.07 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@@H]1O[C@@H]([C@H]([C@@H]1O)O)n1cnc2c1nc(CC)nc2N
  • InChi: 1S/C12H17N5O4/c1-2-6-15-10(13)7-11(16-6)17(4-14-7)12-9(20)8(19)5(3-18)21-12/h4-5,8-9,12,18-20H,2-3H2,1H3,(H2,13,15,16)/t5-,8+,9+,12?/m1/s1
  • InChiKey: VFZXAVDWAOZOPF-CDQRROGXSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis mitogen activated protein kinase 0.0104 0.0119 0.013
Trichomonas vaginalis conserved hypothetical protein 0.0513 0.0751 0.3449
Echinococcus multilocularis smad 0.0149 0.0189 0.0209
Brugia malayi cytoplasmic intermediate filament protein 0.0058 0.0049 0.0145
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0426 0.0617 0.1842
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0104 0.0119 0.0357
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0057 0.0276
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.004 0.0021 0.0061
Brugia malayi isocitrate dehydrogenase 0.0033 0.0009 0.0027
Echinococcus multilocularis lamin 0.0109 0.0127 0.0138
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0055 0.0043 0.0043
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0497 0.0726 0.0819
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0426 0.0617 0.0939
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.1175 0.1774 0.8561
Brugia malayi Pre-SET motif family protein 0.0184 0.0242 0.0724
Onchocerca volvulus 0.0126 0.0153 0.0701
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0071 0.0068 0.0202
Trichomonas vaginalis D-aminoacylase, putative 0.0438 0.0635 0.2917
Echinococcus multilocularis microtubule associated protein 2 0.4246 0.6521 0.7407
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0033 0.001 0.0005
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.004 0.0021 0.0029
Trypanosoma brucei AUT2/APG4/ATG4 cysteine peptidase, putative 0.0062 0.0055 0.0265
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0109 0.0499
Mycobacterium ulcerans hypothetical protein 0.0438 0.0635 0.0622
Schistosoma mansoni nAChR subunit 0.0426 0.0617 0.0917
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0104 0.0119 0.0577
Plasmodium falciparum ferrodoxin reductase-like protein 0.0126 0.0153 0.0721
Echinococcus granulosus Peptidase C54 0.0062 0.0055 0.0076
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0033 0.0009 0.0027
Leishmania major cathepsin L-like protease 0.0064 0.0057 0.0276
Entamoeba histolytica acyl-CoA synthetase, putative 0.0124 0.0149 0.3684
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0085 0.0089 0.1212
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0036 0.0014 0.007
Brugia malayi latrophilin 2 splice variant baaae 0.1044 0.1572 0.4694
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0033 0.001 0.0013
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.0028 0.0128
Echinococcus granulosus TGF beta signal transducer SmadC 0.0149 0.0189 0.0283
Mycobacterium tuberculosis Probable oxidoreductase 0.0044 0.0027 0.002
Trypanosoma cruzi hypothetical protein, conserved 0.0438 0.0635 0.3067
Giardia lamblia Kinase, CMGC MAPK 0.0104 0.0119 0.1651
Toxoplasma gondii propionate-CoA ligase 0.0036 0.0014 0.0053
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0085 0.0089 0.0096
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0126 0.0153 0.0721
Mycobacterium ulcerans oxidoreductase 0.0044 0.0027 0.0012
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.0017 0.0003
Trypanosoma brucei alkyl-dihydroxyacetone phosphate synthase 0.0044 0.0027 0.0129
Loa Loa (eye worm) oxidoreductase 0.0036 0.0014 0.0043
Schistosoma mansoni ferritin light chain 0.0103 0.0117 0.0173
Echinococcus multilocularis survival motor neuron protein 1 0.051 0.0747 0.0843
Brugia malayi Bromodomain containing protein 0.0043 0.0025 0.0074
Loa Loa (eye worm) hypothetical protein 0.0153 0.0195 0.0583
Mycobacterium tuberculosis Probable lipase LipE 0.0438 0.0635 0.0629
Mycobacterium ulcerans DNA polymerase IV 0.004 0.002 0.0005
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0071 0.0068 0.0202
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0033 0.001 0.0046
Schistosoma mansoni nAChR subunit 0.0426 0.0617 0.0917
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0197 0.0262 0.0394
Mycobacterium tuberculosis Probable lipase LipD 0.0438 0.0635 0.0629
Mycobacterium tuberculosis Possible oxidoreductase 0.0044 0.0027 0.002
Loa Loa (eye worm) hypothetical protein 0.0071 0.0068 0.0202
Schistosoma mansoni steroid hormone receptor ad4bp 0.0071 0.0068 0.0099
Mycobacterium ulcerans hypothetical protein 0.0169 0.022 0.0206
Echinococcus multilocularis isocitrate dehydrogenase 0.0033 0.0009 0.0005
Trypanosoma brucei protein kinase, putative 0.0104 0.0119 0.0577
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0937 0.1407 0.1593
Loa Loa (eye worm) hypothetical protein 0.0085 0.0089 0.0267
Brugia malayi hypothetical protein 0.0183 0.0241 0.0719
Loa Loa (eye worm) RNA binding protein 0.0516 0.0755 0.2255
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0085 0.0089 0.0416
Entamoeba histolytica serine/threonine protein kinase, putative 0.0097 0.0109 0.268
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0028 0.0131
Schistosoma mansoni nAChR subunit 0.0426 0.0617 0.0917
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0034 0.0154
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.002 0.0096
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0326 0.0463 0.1381
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0474 0.0691 0.0684
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0438 0.0635 0.0944
Onchocerca volvulus 0.0071 0.0068 0.0311
Loa Loa (eye worm) hypothetical protein 0.0056 0.0045 0.0133
Echinococcus multilocularis thioredoxin glutathione reductase 0.1379 0.209 0.237
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.0362 0.1664
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0119 0.0549
Schistosoma mansoni terminal deoxycytidyl transferase 0.004 0.002 0.0028
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0126 0.0153 0.0168
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0093 0.0101 0.011
Echinococcus granulosus geminin 0.1173 0.1771 0.2711
Onchocerca volvulus 0.0033 0.001 0.0046
Schistosoma mansoni nAChR subunit 0.0197 0.0262 0.0389
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0085 0.0089 0.0075
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0497 0.0726 0.1106
Schistosoma mansoni hypothetical protein 0.1173 0.1771 0.2637
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.0362 0.1664
Loa Loa (eye worm) hypothetical protein 0.0071 0.0068 0.0202
Echinococcus granulosus histone lysine methyltransferase setb 0.0201 0.027 0.0406
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0014 0.0043
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.002 0.0096
Schistosoma mansoni acetyl-CoA synthetase 0.0036 0.0014 0.002
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.003
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0474 0.0691 0.0645
Loa Loa (eye worm) hypothetical protein 0.0426 0.0617 0.1842
Leishmania major alpha glucosidase II subunit, putative 0.0072 0.007 0.0339
Mycobacterium leprae Probable UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD 0.1 0.1503 0.15
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0126 0.0153 0.0168
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0126 0.0153 0.0701
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0055 0.0043 0.0209
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0223 0.1026
Loa Loa (eye worm) transcription factor SMAD2 0.2194 0.3349 1
Schistosoma mansoni neurotransmitter gated ion channel 0.023 0.0313 0.0465
Echinococcus granulosus Nuclear hormone receptor HR96 0.0033 0.001 0.0007
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.0017 0.0014
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.004 0.0021 0.0017
Echinococcus granulosus expressed protein 0.0103 0.0117 0.0171
Brugia malayi mbt repeat family protein 0.0092 0.0101 0.0301
Brugia malayi N-terminal motif family protein 0.0358 0.0511 0.1527
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0197 0.0262 0.0782
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0085 0.0089 0.0096
Loa Loa (eye worm) hypothetical protein 0.0071 0.0068 0.0202
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0045 0.0028 0.0136
Leishmania major D-lactate dehydrogenase-like protein 0.0044 0.0027 0.0129
Mycobacterium tuberculosis Probable oxidoreductase 0.3467 0.5316 0.5313
Brugia malayi MH2 domain containing protein 0.2194 0.3349 1
Mycobacterium tuberculosis Probable conserved integral membrane protein 0.0059 0.0049 0.0042
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.004 0.0021 0.0017
Brugia malayi serine/threonine-protein kinase plk-2 0.0097 0.0109 0.0325
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0126 0.0153 0.0737
Loa Loa (eye worm) hypothetical protein 0.0127 0.0155 0.0462
Loa Loa (eye worm) hypothetical protein 0.0073 0.0071 0.0212
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0063 0.0056 0.0058
Trypanosoma brucei polo-like protein kinase 0.0097 0.0109 0.0525
Loa Loa (eye worm) hypothetical protein 0.0037 0.0016 0.0048
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.004 0.0021 0.0061
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0426 0.0617 0.1842
Leishmania major folylpolyglutamate synthetase 0.0478 0.0697 0.3365
Echinococcus granulosus lamin 0.0109 0.0127 0.0187
Onchocerca volvulus 0.1115 0.1682 0.7724
Mycobacterium tuberculosis Possible flavoprotein 0.0044 0.0027 0.002
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0438 0.0635 0.0622
Leishmania major actin interacting protein-like protein 0.0044 0.0027 0.0129
Leishmania major 4-coumarate:coa ligase-like protein 0.0124 0.0149 0.0721
Onchocerca volvulus 0.0036 0.0014 0.0066
Echinococcus multilocularis chromobox protein 1 0.0075 0.0074 0.0078
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.004 0.0021 0.0061
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0028 0.0131
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0071 0.0068 0.0202
Trypanosoma cruzi AUT2/APG4/ATG4 cysteine peptidase, putative 0.0062 0.0055 0.0265
Treponema pallidum bacterioferrin (TpF1) 0.0103 0.0117 0.0113
Onchocerca volvulus 0.004 0.0021 0.0094
Mycobacterium tuberculosis Probable UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF 0.2397 0.3663 0.3659
Schistosoma mansoni hypothetical protein 0.0044 0.0026 0.0037
Brugia malayi nuclear hormone receptor family member nhr-6 0.0033 0.001 0.003
Echinococcus multilocularis sterol regulatory element binding protein 0.0045 0.0028 0.0026
Loa Loa (eye worm) hypothetical protein 0.1044 0.1572 0.4694
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0474 0.0691 0.0677
Echinococcus granulosus expressed conserved protein 0.0099 0.0112 0.0163
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0085 0.0089 0.0075
Brugia malayi MH2 domain containing protein 0.0149 0.0189 0.0565
Loa Loa (eye worm) hypothetical protein 0.0201 0.027 0.0805
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0071 0.0068 0.0096
Brugia malayi acetyltransferase, GNAT family protein 0.0147 0.0185 0.0553
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0937 0.1407 0.4201
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0071 0.0068 0.0071
Echinococcus granulosus Smad4 0.0149 0.0189 0.0283
Brugia malayi Nuclear hormone receptor-like 1 0.0071 0.0068 0.0202
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0497 0.0726 0.1106
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0474 0.0691 0.0675
Plasmodium vivax dihydrofolate synthase/folylpolyglutamate synthase, putative 0.0478 0.0697 0.3354
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0057 0.0276
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0483 0.0705 0.1075
Onchocerca volvulus Glucosylceramidase homolog 0.0172 0.0223 0.1026
Entamoeba histolytica hypothetical protein 0.023 0.0313 0.7719
Brugia malayi beta-lactamase family protein 0.0438 0.0635 0.1897
Onchocerca volvulus 0.1436 0.2178 1
Onchocerca volvulus 0.0036 0.0014 0.0066
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0124 0.0149 0.0135
Trichomonas vaginalis apoptosis inducing factor, putative 0.0126 0.0153 0.0701
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0126 0.0153 0.0168
Onchocerca volvulus 0.0089 0.0096 0.0439
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0052 0.0039 0.0038
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylmuramyl pentapeptide synthase 0.2397 0.3663 0.3652
Echinococcus multilocularis ubiquitin specific protease 41 0.0085 0.0089 0.0096
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0072 0.007 0.0322
Echinococcus granulosus FAD binding protein type 2 0.0044 0.0027 0.0033
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.002 0.0096
Plasmodium falciparum importin beta, putative 0.003 0.0005 0.0008
Brugia malayi MH1 domain containing protein 0.0149 0.0189 0.0565
Trypanosoma brucei folylpolyglutamate synthase, putative 0.0478 0.0697 0.3365
Schistosoma mansoni autophagin-1 (C54 family) 0.0062 0.0055 0.008
Schistosoma mansoni hypothetical protein 0.0483 0.0705 0.1049
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.4167 0.6398 0.6392
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0126 0.0153 0.0226
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0474 0.0691 0.3322
Schistosoma mansoni intermediate filament proteins 0.0109 0.0127 0.0187
Brugia malayi Heterochromatin protein 1 0.0075 0.0074 0.022
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.002 0.0096
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0028 0.0001 0.0004
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0124 0.0149 0.0143
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0071 0.0068 0.0202
Loa Loa (eye worm) hypothetical protein 0.0438 0.0635 0.1897
Plasmodium falciparum thioredoxin reductase 0.0474 0.0691 0.3322
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0028 0.013
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.004 0.0021 0.0061
Loa Loa (eye worm) hypothetical protein 0.0197 0.0262 0.0782
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0497 0.0726 0.0819
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.1367 0.2071 0.2066
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0119 0.0549
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0152 0.0193 0.0932
Schistosoma mansoni cpg binding protein 0.0146 0.0185 0.0273
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0426 0.0617 0.1842
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.5722 0.8802 1
Brugia malayi hypothetical protein 0.0124 0.015 0.0448
Entamoeba histolytica hypothetical protein 0.0183 0.0241 0.5934
Loa Loa (eye worm) hypothetical protein 0.0055 0.0043 0.0129
Echinococcus multilocularis dna polymerase kappa 0.004 0.002 0.0017
Brugia malayi steroid hormone receptor 0.0071 0.0068 0.0202
Mycobacterium leprae Probable NADPH:adrenodoxin oxidoreductase FprA (NADPH-FERREDOXIN REDUCTASE) 0.0126 0.0153 0.0149
Loa Loa (eye worm) hypothetical protein 0.0197 0.0262 0.0782
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0085 0.0089 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.001 0.0044
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.003
Echinococcus granulosus snurportin 1 0.0324 0.0458 0.0696
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0183 0.0241 0.0361
Brugia malayi exodeoxyribonuclease III family protein 0.0095 0.0105 0.0315
Loa Loa (eye worm) hypothetical protein 0.0123 0.0149 0.0444
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0104 0.0119 0.0577
Echinococcus granulosus lysine specific demethylase 5A 0.0048 0.0033 0.0042
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0036 0.0014 0.007
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0056 0.0044 0.0038
Schistosoma mansoni RAR-like nuclear receptor 0.0071 0.0068 0.0099
Loa Loa (eye worm) hypothetical protein 0.0126 0.0153 0.0456
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0126 0.0153 0.0701
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0071 0.0068 0.0099
Trypanosoma brucei trypanothione reductase 0.1367 0.2071 1
Toxoplasma gondii selenide, water dikinase 0.0126 0.0153 0.0721
Loa Loa (eye worm) hypothetical protein 0.0124 0.0149 0.0446
Plasmodium vivax glutathione reductase, putative 0.1367 0.2071 1
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0049 0.0225
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0058 0.0173
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.002 0.0096
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0197 0.0262 0.0394
Loa Loa (eye worm) hypothetical protein 0.0053 0.0041 0.0122
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0063 0.0056 0.0079
Echinococcus multilocularis transient receptor potential ion channel A 0.0105 0.0121 0.0132
Loa Loa (eye worm) hypothetical protein 0.0051 0.0037 0.0109
Onchocerca volvulus 0.0426 0.0617 0.2832
Echinococcus granulosus tumor protein p63 0.1048 0.1578 0.2413
Loa Loa (eye worm) hypothetical protein 0.0037 0.0016 0.0048
Echinococcus granulosus ferritin 0.0103 0.0117 0.0171
Echinococcus granulosus guanine nucleotide binding protein G protein 0.004 0.0021 0.0024
Plasmodium falciparum phd finger protein, putative 0.0031 0.0007 0.0015
Echinococcus granulosus mothers against decapentaplegic 6 0.0067 0.0062 0.0087
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0197 0.0262 0.0782
Mycobacterium ulcerans oxidoreductase 0.0044 0.0027 0.0012
Mycobacterium ulcerans oxidoreductase 0.0044 0.0027 0.0012
Brugia malayi hypothetical protein 0.0037 0.0016 0.0048
Echinococcus granulosus beta LACTamase domain containing family member 0.0438 0.0635 0.0967
Mycobacterium ulcerans lipase LipD 0.0438 0.0635 0.0622
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0126 0.0153 0.0721
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0092 0.0101 0.0149
Brugia malayi Phospholipase A2 family protein 0.0097 0.0109 0.0325
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0072 0.007 0.0322
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.004 0.002 0.0091
Treponema pallidum oxidoreductase 0.0126 0.0153 0.0149
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0348 0.0496 0.1482
Toxoplasma gondii aldehyde dehydrogenase 0.0063 0.0056 0.0256
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0289 0.0406 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0014 0.0043
Mycobacterium tuberculosis Possible ligase 0.0478 0.0697 0.0691
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0474 0.0691 0.3334
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0009 0.0044
Brugia malayi hypothetical protein 0.051 0.0747 0.2229
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0033 0.001 0.0005
Mycobacterium ulcerans ferredoxin reductase 0.0126 0.0153 0.0138
Loa Loa (eye worm) hypothetical protein 0.0197 0.0262 0.0782
Loa Loa (eye worm) hypothetical protein 0.0042 0.0023 0.0068
Loa Loa (eye worm) hypothetical protein 0.0092 0.0101 0.0302
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0057 0.0276
Brugia malayi RNA binding protein 0.0516 0.0755 0.2255
Schistosoma mansoni thyroid hormone receptor 0.0199 0.0266 0.0395
Trypanosoma cruzi hypothetical protein, conserved 0.0438 0.0635 0.3067
Echinococcus multilocularis short transient receptor potential channel 6 0.0086 0.0092 0.0099
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0474 0.0691 0.1052
Schistosoma mansoni smad1 5 8 and 0.0149 0.0189 0.028
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0324 0.0458 0.1369
Mycobacterium ulcerans beta-lactamase 0.0438 0.0635 0.0622
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0109 0.0499
Brugia malayi ShTK domain containing protein 0.0089 0.0096 0.0286
Brugia malayi Smad1 0.0149 0.0189 0.0565
Mycobacterium tuberculosis Possible oxidoreductase 0.0044 0.0027 0.002
Echinococcus multilocularis short transient receptor potential channel 6 0.0086 0.0092 0.0099
Brugia malayi hypothetical protein 0.0207 0.0278 0.0829
Mycobacterium ulcerans monoxygenase 0.0126 0.0153 0.0138
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.004 0.0021 0.0017
Loa Loa (eye worm) hypothetical protein 0.0097 0.0109 0.0325
Schistosoma mansoni tar DNA-binding protein 0.0516 0.0755 0.1123
Loa Loa (eye worm) histone methyltransferase 0.0052 0.0039 0.0115
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0043 0.0025 0.0022
Loa Loa (eye worm) GABA receptor subunit 0.023 0.0313 0.0935
Trichomonas vaginalis esterase, putative 0.0438 0.0635 0.2917
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0089 0.0096 0.0286
Mycobacterium ulcerans NADH dehydrogenase 0.0126 0.0153 0.0138
Loa Loa (eye worm) hypothetical protein 0.0531 0.0779 0.2326
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0426 0.0617 0.1842
Mycobacterium ulcerans UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase 0.2397 0.3663 0.3654
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0085 0.0089 0.2205
Loa Loa (eye worm) hypothetical protein 0.0092 0.0101 0.0302
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0007 0.0015
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0071 0.0068 0.0099
Onchocerca volvulus 0.0426 0.0617 0.2832
Brugia malayi Bromodomain containing protein 0.0037 0.0016 0.0047
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0028 0.0131
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0033 0.001 0.0007
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0124 0.0149 0.0135
Echinococcus granulosus mothers against decapentaplegic 2 0.0067 0.0062 0.0087
Mycobacterium tuberculosis Probable reductase 0.3119 0.4778 0.4775
Brugia malayi hypothetical protein 0.0033 0.001 0.003
Leishmania major DNA polymerase kappa, putative 0.004 0.002 0.0096
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.1175 0.1774 0.1762
Brugia malayi RNA, U transporter 1 0.0086 0.0092 0.0273
Brugia malayi conserved hypotetical protein 0.0033 0.001 0.003
Loa Loa (eye worm) hypothetical protein 0.0197 0.0262 0.0782
Echinococcus multilocularis jumonji domain containing protein 0.0043 0.0025 0.0023
Leishmania major mitochondrial DNA polymerase beta 0.0321 0.0454 0.2194
Loa Loa (eye worm) hypothetical protein 0.0438 0.0635 0.1897
Schistosoma mansoni coup transcription factor 0.0071 0.0068 0.0099
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0036 0.0014 0.0053
Schistosoma mansoni hypothetical protein 0.0483 0.0705 0.1049
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0104 0.0119 0.0577
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0097 0.0109 0.0118
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0036 0.0014 0.0011
Loa Loa (eye worm) hypothetical protein 0.0426 0.0617 0.1842
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0109 0.0499
Brugia malayi Probable ClpP-like protease 0.0085 0.0089 0.0267
Loa Loa (eye worm) hypothetical protein 0.0124 0.0149 0.0446
Leishmania major hypothetical protein, conserved 0.0438 0.0635 0.3067
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0059 0.0049 0.0032
Brugia malayi mothers against decapentaplegic homolog 3 0.0067 0.0062 0.0184
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0126 0.0153 0.0701
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.016 0.0206 0.0229
Loa Loa (eye worm) hypothetical protein 0.0089 0.0096 0.0286
Trichomonas vaginalis Regulatory protein uhpC, putative 0.0059 0.0049 0.0225
Schistosoma mansoni hypothetical protein 0.0128 0.0157 0.0232
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.004 0.002 0.0023
Mycobacterium ulcerans flavoprotein 0.0044 0.0027 0.0012
Echinococcus granulosus histone acetyltransferase KAT2B 0.014 0.0175 0.0261
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0063 0.0056 0.005
Loa Loa (eye worm) hypothetical protein 0.0036 0.0014 0.0043
Mycobacterium leprae conserved hypothetical protein 0.0044 0.0027 0.0023
Brugia malayi MH2 domain containing protein 0.0149 0.0189 0.0565
Schistosoma mansoni nuclear hormone receptor 0.0033 0.001 0.0013
Echinococcus multilocularis nuclear receptor nhr 48 0.0033 0.001 0.0005
Onchocerca volvulus 0.023 0.0313 0.1437
Loa Loa (eye worm) isocitrate dehydrogenase 0.0033 0.0009 0.0027
Echinococcus multilocularis beta LACTamase domain containing family member 0.0438 0.0635 0.0716
Loa Loa (eye worm) hypothetical protein 0.0197 0.0262 0.0782
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0483 0.0705 0.2106
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.001 0.0044
Mycobacterium tuberculosis Putative ferredoxin reductase 0.3119 0.4778 0.4775
Schistosoma mansoni transient receptor potential channel 0.0086 0.0092 0.0135
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0124 0.0149 0.0135
Trypanosoma cruzi actin interacting protein-like protein, putative 0.0044 0.0027 0.0129
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0072 0.007 0.1732
Brugia malayi Cation transporter family protein 0.1115 0.1682 0.5022
Echinococcus multilocularis peptidase Clp (S14 family) 0.0056 0.0044 0.0044
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0126 0.0153 0.0737
Schistosoma mansoni Smad4 0.0067 0.0062 0.009
Leishmania major cathepsin L-like protease 0.0064 0.0057 0.0276
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0426 0.0617 0.0695
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0049 0.0225
Plasmodium falciparum ataxin-2 like protein, putative 0.0207 0.0278 0.1325
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0045 0.0028 0.0085
Loa Loa (eye worm) hypothetical protein 0.0067 0.0062 0.0184
Echinococcus granulosus chromobox protein 1 0.0075 0.0074 0.0105
Loa Loa (eye worm) hypothetical protein 0.0089 0.0096 0.0286
Loa Loa (eye worm) hypothetical protein 0.0426 0.0617 0.1842
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0085 0.0089 0.0129
Schistosoma mansoni peptidase Clp (S14 family) 0.0085 0.0089 0.0132
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.002 0.0096
Echinococcus multilocularis polycomb protein SCMH1 0.0102 0.0116 0.0126
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0126 0.0153 0.0721
Echinococcus granulosus chromobox protein 1 0.0075 0.0074 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.001 0.0044
Loa Loa (eye worm) hypothetical protein 0.0197 0.0262 0.0782
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0095 0.0105 0.0509
Schistosoma mansoni hypothetical protein 0.1173 0.1771 0.2637
Schistosoma mansoni hypothetical protein 0.1044 0.1572 0.234
Onchocerca volvulus 0.0109 0.0127 0.0582
Mycobacterium leprae PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) 0.0126 0.0153 0.0149
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0033 0.0009 0.0006
Schistosoma mansoni jumonji domain containing protein 0.0081 0.0084 0.0123
Onchocerca volvulus 0.004 0.0021 0.0094
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0126 0.0153 0.0737
Schistosoma mansoni tar DNA-binding protein 0.0516 0.0755 0.1123
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0197 0.0262 0.0292
Loa Loa (eye worm) hypothetical protein 0.0426 0.0617 0.1842
Trichomonas vaginalis glucose-6-phosphate translocase, putative 0.0059 0.0049 0.0225
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0474 0.0691 0.3334
Loa Loa (eye worm) hypothetical protein 0.0197 0.0262 0.0782
Loa Loa (eye worm) ACC-1 protein 0.0426 0.0617 0.1842
Loa Loa (eye worm) MH1 domain-containing protein 0.0067 0.0062 0.0184
Toxoplasma gondii hypothetical protein 0.0052 0.0038 0.0168
Echinococcus multilocularis FTZ F1 alpha 0.0071 0.0068 0.0071
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0126 0.0153 0.0737
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0037 0.0016 0.0022
Trichomonas vaginalis D-aminoacylase, putative 0.0438 0.0635 0.2917
Mycobacterium ulcerans NADPH dependent 2,4-dienoyl-CoA reductase FadH 0.0126 0.0153 0.0138
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0531 0.0779 0.2326
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0037 0.0016 0.0012
Mycobacterium leprae Probable lipase LipE 0.0438 0.0635 0.0632
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0009 0.0005
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0516 0.0755 0.2255
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0028 0.0128
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.004 0.0021 0.0029
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.004 0.0021 0.0029
Loa Loa (eye worm) hypothetical protein 0.0463 0.0674 0.2012
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0036 0.0014 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0049 0.0225
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0009 0.0027
Treponema pallidum UDP-N-acetylenolpyruvoylglucosamine reductase 0.6498 1 1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0017 0.0079
Schistosoma mansoni kinase 0.005 0.0035 0.0051
Schistosoma mansoni nuclear receptor 0.0033 0.001 0.0013
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0092 0.0101 0.0463
Trypanosoma brucei NADH dehydrogenase 0.0126 0.0153 0.0737
Echinococcus granulosus FTZ F1 alpha 0.0071 0.0068 0.0096
Loa Loa (eye worm) ACC-1 protein 0.0426 0.0617 0.1842
Brugia malayi nuclear hormone receptor 0.0033 0.001 0.003
Schistosoma mansoni tar DNA-binding protein 0.0516 0.0755 0.1123
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0056 0.0044 0.0038
Giardia lamblia Kinase, PLK 0.0097 0.0109 0.1494
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0223 0.1026
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0001 0.0004
Treponema pallidum exodeoxyribonuclease (exoA) 0.0095 0.0105 0.0102
Schistosoma mansoni transcription factor LCR-F1 0.0183 0.0241 0.0357
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0149 0.0189 0.0209
Mycobacterium ulcerans NADH dehydrogenase Ndh 0.0126 0.0153 0.0138
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.002 0.0096
Mycobacterium tuberculosis Conserved hypothetical protein 0.004 0.002 0.0013
Echinococcus granulosus Nuclear hormone receptor HR96 0.0033 0.001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0426 0.0617 0.1842
Onchocerca volvulus 0.0033 0.0009 0.0041
Onchocerca volvulus 0.0124 0.0149 0.0686
Mycobacterium ulcerans UDP-N-acetylmuramate--L-alanine ligase 0.4641 0.7131 0.7127
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0014 0.0008
Loa Loa (eye worm) nuclear hormone receptor 0.0123 0.0148 0.0443
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0053 0.0041 0.0059
Schistosoma mansoni ap endonuclease 0.0095 0.0105 0.0155
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0036 0.0014 0.0008
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0426 0.0617 0.0939
Loa Loa (eye worm) inositol-1 0.0038 0.0017 0.0051
Loa Loa (eye worm) hypothetical protein 0.0044 0.0027 0.008
Brugia malayi nuclear hormone receptor 0.0071 0.0068 0.0202
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0438 0.0635 0.1897
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0197 0.0262 0.0782
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0104 0.0119 0.0577
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0196 0.0261 0.0387
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0056 0.0044 0.0041
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.003
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.004 0.0021 0.0094
Loa Loa (eye worm) hypothetical protein 0.0483 0.0705 0.2106
Echinococcus multilocularis Smad4 0.0149 0.0189 0.0209
Trypanosoma cruzi alkyl-dihydroxyacetone phosphate synthase, putative 0.0044 0.0027 0.0129
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0033 0.001 0.003
Mycobacterium ulcerans bacterioferritin BfrA 0.0103 0.0117 0.0103
Treponema pallidum UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase (murE) 0.2397 0.3663 0.3661
Loa Loa (eye worm) hypothetical protein 0.0124 0.015 0.0448
Giardia lamblia NADH oxidase lateral transfer candidate 0.0474 0.0691 1
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.004 0.0021 0.0029
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0126 0.0153 0.0136
Schistosoma mansoni folylpolyglutamate synthase 0.0478 0.0697 0.1037
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0141 0.0177 0.017
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0426 0.0617 0.1842
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0126 0.0153 0.3765
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0126 0.0153 0.0226
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0358 0.0511 0.2348
Plasmodium vivax ataxin-2 like protein, putative 0.0207 0.0278 0.1325
Loa Loa (eye worm) hypothetical protein 0.0426 0.0617 0.1842
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0007 0.0015
Echinococcus granulosus mothers against decapentaplegic 5 0.0149 0.0189 0.0283
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0126 0.0153 0.0168
Schistosoma mansoni smad 0.0067 0.0062 0.009
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.0362 0.1664
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0023 0.0105
Echinococcus granulosus SAM and MBT domain containing protein 0.0092 0.0101 0.0147
Echinococcus granulosus mixed lineage leukemia protein mll 0.0043 0.0025 0.003
Schistosoma mansoni tar DNA-binding protein 0.0516 0.0755 0.1123
Mycobacterium ulcerans acyl-CoA synthetase 0.0124 0.0149 0.0135
Loa Loa (eye worm) hypothetical protein 0.0085 0.0089 0.0267
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0126 0.0153 0.0146
Brugia malayi AMP-binding enzyme family protein 0.0124 0.0149 0.0446
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.4167 0.6398 0.6397
Mycobacterium tuberculosis Probable UDP-N-acetylmuramate-alanine ligase MurC 0.2244 0.3426 0.3421
Onchocerca volvulus 0.0426 0.0617 0.2832
Toxoplasma gondii LsmAD domain-containing protein 0.0207 0.0278 0.1325
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.1175 0.1774 0.1733
Giardia lamblia DINP protein human, muc B family 0.004 0.002 0.0195
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0197 0.0262 0.0292
Echinococcus multilocularis glutamate synthase 0.0126 0.0153 0.0168
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0049 0.0225
Trypanosoma brucei unspecified product 0.004 0.002 0.0096
Trichomonas vaginalis antibiotic synthetase, putative 0.0036 0.0014 0.0066
Schistosoma mansoni nAChR subunit 0.0426 0.0617 0.0917
Treponema pallidum UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase (murF) 0.2397 0.3663 0.3661
Loa Loa (eye worm) hypothetical protein 0.1528 0.2319 0.6925
Onchocerca volvulus 0.0102 0.0116 0.0531
Loa Loa (eye worm) hypothetical protein 0.0426 0.0617 0.1842
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.1115 0.1682 0.2504
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0057 0.0276
Schistosoma mansoni nuclear hormone receptor 0.0033 0.001 0.0013
Chlamydia trachomatis bifunctional UDP-N-acetylmuramate-alanine ligase/D-alanine-D-alanine ligase 0.4641 0.7131 0.7117
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0089 0.0411
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0005 0.0025
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0072 0.007 0.021
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0085 0.0089 0.0041
Loa Loa (eye worm) hypothetical protein 0.0197 0.0262 0.0782
Brugia malayi nuclear receptor RXR 0.0033 0.001 0.003
Echinococcus multilocularis FAD binding protein, type 2 0.0044 0.0027 0.0025
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0045 0.0028 0.0117
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0036 0.0014 0.0008
Onchocerca volvulus Huntingtin homolog 0.0124 0.015 0.0689
Loa Loa (eye worm) hypothetical protein 0.0124 0.0149 0.0446
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.002 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0004 0.0019
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0426 0.0617 0.0917
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.007 0.0322
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0085 0.0089 0.0411
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0036 0.0014 0.0043
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0126 0.0153 0.0737
Schistosoma mansoni ferritin light chain 0.0103 0.0117 0.0173
Trypanosoma cruzi PAB1-binding protein , putative 0.0207 0.0278 0.134
Chlamydia trachomatis thioredoxin reductase 0.0126 0.0153 0.0104
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0426 0.0617 0.1842
Brugia malayi FolC bifunctional protein 0.0478 0.0697 0.2081
Mycobacterium leprae PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA 0.2992 0.4583 0.4581
Mycobacterium tuberculosis Probable hydrolase 0.0438 0.0635 0.0629
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0107 0.0124 0.0183
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.003
Trichomonas vaginalis CAMK family protein kinase 0.0049 0.0034 0.0154
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0095 0.0105 0.0315
Schistosoma mansoni hypothetical protein 0.0104 0.0119 0.0176
Leishmania major 4-coumarate:coa ligase-like protein 0.0124 0.0149 0.0721
Brugia malayi mbt repeat family protein 0.0092 0.0101 0.0301
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0011 0.0007
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0014 0.0008
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.004 0.0021 0.0061
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0062 0.0055 0.0252
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0085 0.0089 0.0096
Trichomonas vaginalis sucrase-isomaltase, putative 0.0072 0.007 0.0322
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0095 0.0105 0.0493
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.004 0.002 0.0059
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0106 0.0121 0.2993
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0057 0.0276
Echinococcus granulosus jumonji domain containing protein 0.0043 0.0025 0.0031
Onchocerca volvulus 0.0438 0.0635 0.2917
Treponema pallidum UDP-N-acetylmuramoylalanine--D-glutamate ligase (murD) 0.2441 0.373 0.3728
Brugia malayi nuclear receptor NHR-67 0.0033 0.001 0.003
Schistosoma mansoni hypothetical protein 0.0093 0.0101 0.015
Brugia malayi follicle stimulating hormone receptor 0.0978 0.1469 0.4387
Schistosoma mansoni myelin transcription factor 1 myt1 0.0052 0.0039 0.0057
Echinococcus multilocularis lysosomal alpha glucosidase 0.0326 0.0463 0.052
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0052 0.0039 0.0039
Plasmodium falciparum thioredoxin reductase 0.1367 0.2071 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.0406 0.1862
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.004 0.0021 0.0094
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0126 0.0153 0.0138
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0009 0.0005
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0062 0.0055 0.0252
Loa Loa (eye worm) FolC protein 0.0478 0.0697 0.2081
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0087 0.0093 0.0087
Echinococcus granulosus lysosomal alpha glucosidase 0.0326 0.0463 0.0702
Brugia malayi jmjC domain containing protein 0.0048 0.0033 0.0097
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0057 0.0276
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.003
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0152 0.0193 0.0932
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0126 0.0153 0.0226
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0071 0.0068 0.0096
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0085 0.0089 0.0411
Mycobacterium tuberculosis Conserved protein 0.0438 0.0635 0.0629
Brugia malayi hypothetical protein 0.004 0.0021 0.0061
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.3467 0.5316 0.5313
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0043 0.0025 0.0022
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.023 0.0313 0.0465
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.3119 0.4778 0.4775
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0126 0.0153 0.2136
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0126 0.0153 0.3765
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0071 0.0068 0.0096
Schistosoma mansoni neurotransmitter gated ion channel 0.0197 0.0262 0.0389
Loa Loa (eye worm) cytochrome P450 family protein 0.0058 0.0047 0.0141
Echinococcus multilocularis expressed conserved protein 0.0099 0.0112 0.0121
Trypanosoma cruzi L-galactonolactone oxidase, putative 0.0044 0.0027 0.0129
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.023 0.0313 0.0935
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0223 0.1026
Schistosoma mansoni hypothetical protein 0.0183 0.0241 0.0357
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.004 0.002 0.0013
Brugia malayi ecdysone receptor 0.0033 0.001 0.003
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0007 0.0008
Echinococcus granulosus polycomb protein SCMH1 0.0102 0.0116 0.017
Loa Loa (eye worm) hypothetical protein 0.0919 0.1378 0.4115
Trypanosoma cruzi PAB1-binding protein , putative 0.0207 0.0278 0.134
Echinococcus multilocularis tar DNA binding protein 0.0516 0.0755 0.0853
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0085 0.0089 0.0267
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.1175 0.1774 0.1771
Plasmodium falciparum glutathione reductase 0.1367 0.2071 1
Trypanosoma brucei L-galactonolactone oxidase 0.0044 0.0027 0.0129
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0438 0.0635 0.1897
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0085 0.0089 0.0432
Brugia malayi Thioredoxin reductase 0.1367 0.2071 0.6185
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.003
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0201 0.027 0.04
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.004 0.0021 0.0061
Onchocerca volvulus 0.0153 0.0195 0.0897
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0104 0.0119 0.0561
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.3467 0.5316 0.5315
Onchocerca volvulus Putative folylpolyglutamate synthase 0.0478 0.0697 0.3201
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0474 0.0691 0.3334
Loa Loa (eye worm) hypothetical protein 0.0426 0.0617 0.1842
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0053 0.004 0.0053
Brugia malayi Cation transporter family protein 0.0426 0.0617 0.1842
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0032 0.0007 0.0002
Loa Loa (eye worm) hypothetical protein 0.023 0.0313 0.0935
Giardia lamblia Fructose-bisphosphate aldolase 0.0289 0.0406 0.5834
Loa Loa (eye worm) hypothetical protein 0.0037 0.0016 0.0048
Echinococcus granulosus histone acetyltransferase MYST2 0.0052 0.0039 0.0053
Loa Loa (eye worm) hypothetical protein 0.0426 0.0617 0.1842
Schistosoma mansoni hypothetical protein 0.125 0.189 0.2813
Giardia lamblia Glutamate synthase 0.0126 0.0153 0.2136
Mycobacterium leprae ProbableUDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF 0.2397 0.3663 0.3661
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0018 0.0072
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0483 0.0705 0.0796
Schistosoma mansoni cellular tumor antigen P53 0.0153 0.0195 0.0289
Mycobacterium tuberculosis Possible oxidoreductase 0.0044 0.0027 0.002
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0238 0.1092
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.023 0.0313 0.0935
Brugia malayi hypothetical protein 0.0059 0.0049 0.0146
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.3467 0.5316 0.5313
Loa Loa (eye worm) hypothetical protein 0.0071 0.0068 0.0202
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0426 0.0617 0.0695
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0036 0.0014 0.0043
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0097 0.0109 0.0325
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0014 0.0008
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0152 0.0193 0.0932
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0093 0.0101 0.0148
Brugia malayi hypothetical protein 0.0037 0.0016 0.0048
Mycobacterium tuberculosis Probable esterase LipL 0.0438 0.0635 0.0629
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0497 0.0726 0.2167
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0126 0.0153 0.0721
Loa Loa (eye worm) hypothetical protein 0.0438 0.0635 0.1897
Schistosoma mansoni transient receptor potential channel 0.0123 0.0149 0.022
Loa Loa (eye worm) hypothetical protein 0.0207 0.0278 0.0829
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.003
Onchocerca volvulus 0.0438 0.0635 0.2917
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0474 0.0691 0.3334
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0062 0.0055 0.008
Leishmania major acetyl-CoA synthetase, putative 0.0036 0.0014 0.007
Onchocerca volvulus Putative nachr subunit 0.0497 0.0726 0.3333
Loa Loa (eye worm) hypothetical protein 0.0068 0.0064 0.0191
Echinococcus granulosus guanine nucleotide binding protein G protein 0.004 0.0021 0.0024
Echinococcus granulosus thioredoxin glutathione reductase 0.1379 0.209 0.3199
Loa Loa (eye worm) G protein alpha subunit 3 0.004 0.0021 0.0061
Loa Loa (eye worm) TAR-binding protein 0.0516 0.0755 0.2255
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0126 0.0153 0.0737
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0102 0.0116 0.0126
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0011 0.0004
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0174 0.0227 0.0341
Schistosoma mansoni trimeric G-protein alpha o subunit 0.004 0.0021 0.0029
Loa Loa (eye worm) intermediate filament protein 0.0109 0.0127 0.0378
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0049 0.0225
Schistosoma mansoni importin beta-1 0.003 0.0005 0.0006
Schistosoma mansoni acetylcholine receptor-related 0.0197 0.0262 0.0389
Trichomonas vaginalis glutamate synthase, putative 0.0126 0.0153 0.0701
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0426 0.0617 0.0939
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0071 0.0068 0.0202
Echinococcus multilocularis tumor protein p63 0.1048 0.1578 0.1788
Echinococcus multilocularis nAChR subunit 0.023 0.0313 0.035
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0017 0.0083
Mycobacterium tuberculosis Conserved hypothetical protein 0.0169 0.022 0.0213
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0126 0.0153 0.0146
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0426 0.0617 0.0917
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.004 0.0021 0.0061
Trichomonas vaginalis D-aminoacylase, putative 0.0438 0.0635 0.2917
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0497 0.0726 0.2167
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0104 0.0119 0.0577
Loa Loa (eye worm) hypothetical protein 0.0438 0.0635 0.1897
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0071 0.0068 0.0202
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0474 0.0691 0.3334
Schistosoma mansoni serine/threonine protein kinase 0.0097 0.0109 0.016
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0036 0.0014 0.0043
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0036 0.0014 0.0008
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.0109 0.0525
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0474 0.0691 0.3322
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0007 0.0002
Trypanosoma cruzi alkyl-dihydroxyacetone phosphate synthase, putative 0.0044 0.0027 0.0129
Loa Loa (eye worm) hypothetical protein 0.004 0.0021 0.0061
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0978 0.1469 0.4387
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0085 0.0089 0.0416
Onchocerca volvulus 0.0033 0.001 0.0046
Mycobacterium leprae Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0126 0.0153 0.0149
Loa Loa (eye worm) hypothetical protein 0.0426 0.0617 0.1842
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0071 0.0068 0.0202
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.001 0.0044
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0483 0.0705 0.0796
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0104 0.0119 0.0577
Mycobacterium ulcerans oxidoreductase 0.0044 0.0027 0.0012
Toxoplasma gondii isocitrate dehydrogenase 0.0033 0.0009 0.0027
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0426 0.0617 0.0695
Mycobacterium ulcerans bacterioferritin BfrB 0.0103 0.0117 0.0103
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0126 0.0153 0.0721
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0147 0.0185 0.0274
Onchocerca volvulus 0.0036 0.0014 0.0066
Onchocerca volvulus 0.0189 0.025 0.1148
Chlamydia trachomatis UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.4167 0.6398 0.6381
Trypanosoma cruzi L-galactonolactone oxidase 0.0044 0.0027 0.0129
Echinococcus granulosus tar DNA binding protein 0.0516 0.0755 0.1151
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0119 0.0549
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0092 0.0101 0.0095
Trichomonas vaginalis glucosylceramidase, putative 0.0181 0.0238 0.1092
Loa Loa (eye worm) hypothetical protein 0.0438 0.0635 0.1897
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0085 0.0089 0.0416
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0426 0.0617 0.1842
Schistosoma mansoni hypothetical protein 0.0044 0.0026 0.0037
Mycobacterium tuberculosis Probable UDP-N-acetylenolpyruvoylglucosamine reductase MurB (UDP-N-acetylmuramate dehydrogenase) 0.6498 1 1
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0089 0.0096 0.0286
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0426 0.0617 0.1842
Mycobacterium ulcerans folylpolyglutamate synthase protein FolC 0.1441 0.2185 0.2174
Schistosoma mansoni hypothetical protein 0.0483 0.0705 0.1049
Schistosoma mansoni patched 1 0.0045 0.0028 0.0041
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0087 0.0093 0.0087
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0036 0.0014 0.007
Schistosoma mansoni transient receptor potential channel 0.0086 0.0092 0.0135
Brugia malayi Transient-receptor-potential like protein 0.0055 0.0043 0.0129
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0036 0.0014 0.0053
Brugia malayi photoreceptor-specific nuclear receptor 0.0071 0.0068 0.0202
Loa Loa (eye worm) Smad1 0.0149 0.0189 0.0565
Trichomonas vaginalis set domain proteins, putative 0.1436 0.2178 1
Trichomonas vaginalis dihydrofolate synthase/folylpolyglutamate synthase, putative 0.0478 0.0697 0.3201
Loa Loa (eye worm) hypothetical protein 0.0083 0.0086 0.0257
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0483 0.0705 0.1075
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0045 0.0028 0.0136
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0124 0.0149 0.0135
Loa Loa (eye worm) hypothetical protein 0.0124 0.015 0.0448
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0126 0.0153 0.0737
Brugia malayi hypothetical protein 0.0133 0.0164 0.0491
Brugia malayi TAR-binding protein 0.0516 0.0755 0.2255
Schistosoma mansoni cpg binding protein 0.0157 0.02 0.0297
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0937 0.1407 0.2151
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0474 0.0691 0.0677
Onchocerca volvulus 0.023 0.0313 0.1437
Brugia malayi Pre-SET motif family protein 0.1262 0.1909 0.57
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0033 0.0009 0.0005
Brugia malayi glutathione reductase 0.1367 0.2071 0.6185
Schistosoma mansoni Smad4 0.0067 0.0062 0.009
Loa Loa (eye worm) hypothetical protein 0.0438 0.0635 0.1897
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0104 0.0119 0.0356
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0004 0.0019
Trichomonas vaginalis Hexuronate transporter, putative 0.0059 0.0049 0.0225
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.007 0.0339
Brugia malayi CHE-14 protein 0.0045 0.0028 0.0085
Onchocerca volvulus Protein ultraspiracle homolog 0.0071 0.0068 0.0311
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.023 0.0313 0.0935
Trypanosoma cruzi major cysteine proteinase, putative 0.005 0.0036 0.0173
Brugia malayi jmjC domain containing protein 0.0102 0.0116 0.0347
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.0017 0.0424
Chlamydia trachomatis UDP-N-acetylmuramoylalanine--D-glutamate ligase 0.2441 0.373 0.3699
Brugia malayi tailless protein 0.0033 0.001 0.003
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.0406 0.1862
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.004 0.0021 0.0029
Plasmodium vivax importin-beta 2, putative 0.003 0.0005 0.0008
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.4167 0.6398 0.6393
Schistosoma mansoni hypothetical protein 0.0527 0.0773 0.1149
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0126 0.0153 0.0737
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0124 0.0149 0.0143
Brugia malayi Peptidase family C54 containing protein 0.0062 0.0055 0.0164
Loa Loa (eye worm) hypothetical protein 0.0107 0.0124 0.0369
Brugia malayi nuclear receptor NHR-88 0.0033 0.001 0.003
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.001 0.0044
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0474 0.0691 0.3334
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0056 0.0042
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0474 0.0691 0.3334
Loa Loa (eye worm) hypothetical protein 0.0051 0.0037 0.0109
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0071 0.0068 0.0099
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0426 0.0617 0.1842
Schistosoma mansoni jumonji/arid domain-containing protein 0.0048 0.0033 0.0047
Loa Loa (eye worm) hypothetical protein 0.023 0.0313 0.0935
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0141 0.0177 0.0163
Brugia malayi intermediate filament protein 0.0109 0.0127 0.0378
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0474 0.0691 0.3322
Trypanosoma cruzi cruzipain precursor, putative 0.0064 0.0057 0.0276
Leishmania major hypothetical protein, conserved 0.0126 0.0153 0.0737
Leishmania major cathepsin L-like protease 0.0064 0.0057 0.0276
Entamoeba histolytica hypothetical protein 0.0183 0.0241 0.5934
Echinococcus multilocularis thyroid hormone receptor alpha 0.0199 0.0266 0.0297
Onchocerca volvulus 0.0109 0.0127 0.0582
Schistosoma mansoni inositol monophosphatase 0.0038 0.0017 0.0024
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0126 0.0153 0.0456
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0017 0.0083
Echinococcus granulosus nuclear receptor nhr 48 0.0033 0.001 0.0007
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0033 0.001 0.0013
Echinococcus multilocularis lamin dm0 0.0109 0.0127 0.0138
Mycobacterium ulcerans UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 0.2441 0.373 0.3721
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0126 0.0153 0.0168
Schistosoma mansoni smad1 5 8 and 0.0149 0.0189 0.028
Schistosoma mansoni apoferritin-2 0.0103 0.0117 0.0173
Plasmodium vivax acyl-CoA synthetase, putative 0.0092 0.0101 0.0472
Schistosoma mansoni DNA polymerase eta 0.004 0.002 0.0028
Plasmodium vivax hypothetical protein, conserved 0.0438 0.0635 0.3055
Loa Loa (eye worm) hypothetical protein 0.0197 0.0262 0.0782
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0321 0.0454 0.2194
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0126 0.0153 0.0146
Loa Loa (eye worm) hypothetical protein 0.0055 0.0044 0.0132
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.0362 0.1664
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0183 0.0241 0.0268
Schistosoma mansoni ap endonuclease 0.0095 0.0105 0.0155
Treponema pallidum folylpolyglutamate synthetase (folC) 0.1441 0.2185 0.2182
Echinococcus granulosus expressed protein 0.004 0.0021 0.0024
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0426 0.0617 0.0695
Echinococcus multilocularis expressed protein 0.004 0.0021 0.0017
Schistosoma mansoni retinoic acid receptor RXR 0.0071 0.0068 0.0099
Schistosoma mansoni acetylcholine receptor subunit beta 0.0197 0.0262 0.0389
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0087 0.0093 0.0087
Trypanosoma cruzi hypothetical protein, conserved 0.0072 0.007 0.0339
Echinococcus granulosus sterol regulatory element binding protein 0.0045 0.0028 0.0036
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0036 0.0014 0.007
Leishmania major L-gulonolactone oxidase, putative 0.0044 0.0027 0.0129
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0085 0.0089 0.0041
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0201 0.027 0.0301
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0009 0.0044
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0348 0.0496 0.1482
Loa Loa (eye worm) hypothetical protein 0.023 0.0313 0.0935
Mycobacterium tuberculosis Probable oxidoreductase 0.0044 0.0027 0.002
Loa Loa (eye worm) hypothetical protein 0.0426 0.0617 0.1842
Brugia malayi Niemann-Pick C1 protein precursor 0.0106 0.0121 0.0362
Loa Loa (eye worm) MH1 domain-containing protein 0.0149 0.0189 0.0565
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylmuramate-alanine ligase 0.4641 0.7131 0.7126
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0937 0.1407 0.2151
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0382 0.0549 0.0619
Schistosoma mansoni lamin 0.0109 0.0127 0.0187
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0049 0.0225
Echinococcus multilocularis peregrin 0.0037 0.0016 0.0012
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0032 0.0007 0.0009
Trichomonas vaginalis bromodomain-containing protein, putative 0.0045 0.0028 0.0127
Loa Loa (eye worm) DR-78 0.0033 0.001 0.003
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0474 0.0691 0.3322
Schistosoma mansoni sex comb on midleg homolog 0.0102 0.0116 0.0171
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0036 0.0014 0.0011
Schistosoma mansoni hypothetical protein 0.0044 0.0026 0.0037
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0474 0.0691 0.3322
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.007 0.0322
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0052 0.0039 0.0053
Echinococcus multilocularis glycine receptor subunit beta 0.0426 0.0617 0.0695
Schistosoma mansoni glutamate synthase 0.0126 0.0153 0.0226
Echinococcus granulosus GPCR family 2 0.0483 0.0705 0.1075
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0126 0.0153 0.0146
Loa Loa (eye worm) hypothetical protein 0.004 0.002 0.0059
Brugia malayi PHD-finger family protein 0.0038 0.0016 0.0049
Echinococcus multilocularis lysine specific demethylase 5A 0.0038 0.0017 0.0013
Onchocerca volvulus 0.0197 0.0262 0.1203
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0085 0.0089 0.0132
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0095 0.0105 0.2599
Brugia malayi glutamate synthase 0.0126 0.0153 0.0456
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.007 0.0322
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0937 0.1407 0.4201
Echinococcus multilocularis Niemann Pick C1 protein 0.0151 0.0191 0.0212
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0014 0.0043
Schistosoma mansoni tyrosinase precursor 0.0089 0.0096 0.0141
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0426 0.0617 0.0939
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0095 0.0105 0.0509
Loa Loa (eye worm) hypothetical protein 0.0045 0.0028 0.0085
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.023 0.0313 0.0465
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0109 0.0499
Echinococcus granulosus glycine receptor subunit alpha 1 0.0426 0.0617 0.0939
Mycobacterium ulcerans thioredoxin reductase TrxB2 0.0126 0.0153 0.0138
Trichomonas vaginalis CMGC family protein kinase 0.0104 0.0119 0.0549
Echinococcus granulosus short transient receptor potential channel 6 0.0086 0.0092 0.0133
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0184 0.0242 0.1155
Loa Loa (eye worm) MH2 domain-containing protein 0.0149 0.0189 0.0565
Trypanosoma brucei unspecified product 0.0027 0.0001 0.0004
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0023 0.0105
Mycobacterium tuberculosis Probable dehydrogenase 0.0044 0.0027 0.002
Plasmodium vivax ferrodoxin reductase, putative 0.0126 0.0153 0.0721
Onchocerca volvulus Alhambra homolog 0.0031 0.0007 0.003
Loa Loa (eye worm) hypothetical protein 0.003 0.0005 0.0015
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0071 0.0068 0.0071
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0071 0.0068 0.0071
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0095 0.0105 0.0493
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0071 0.0068 0.0202
Echinococcus granulosus short transient receptor potential channel 6 0.0086 0.0092 0.0133
Echinococcus granulosus nAChR subunit 0.023 0.0313 0.0473
Schistosoma mansoni sulfide quinone reductase 0.0126 0.0153 0.0226
Trypanosoma cruzi actin interacting protein-like protein, putative 0.0044 0.0027 0.0129
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0109 0.0499
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0033 0.001 0.0007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0057 0.0276
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0057 0.0276
Brugia malayi MAP kinase sur-1 0.0104 0.0119 0.0357
Schistosoma mansoni ferritin 0.0103 0.0117 0.0173
Brugia malayi Nuclear hormone receptor-like 1 0.0037 0.0016 0.0048
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0005 0.0025
Loa Loa (eye worm) hypothetical protein 0.0033 0.0009 0.0027
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0126 0.0153 0.3765
Echinococcus granulosus peptidase Clp S14 family 0.0056 0.0044 0.006
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.1115 0.1682 0.2504
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0426 0.0617 0.0917
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0036 0.0014 0.0008
Mycobacterium tuberculosis Conserved protein 0.0438 0.0635 0.0629
Echinococcus granulosus microtubule associated protein 2 0.4246 0.6521 1
Onchocerca volvulus 0.0089 0.0096 0.0439
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0474 0.0691 0.3334
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.004 0.0021 0.0029
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.0406 0.1862
Loa Loa (eye worm) ShTK domain-containing protein 0.0089 0.0096 0.0286
Echinococcus granulosus mitogen activated protein kinase 0.0104 0.0119 0.0175
Mycobacterium ulcerans hypothetical protein 0.0126 0.0153 0.0138
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0044 0.0027 0.0023
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0056 0.0042
Echinococcus granulosus TRP transient receptor potential channel 0.0055 0.0043 0.0058
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0197 0.0262 0.0292
Mycobacterium ulcerans aldehyde dehydrogenase 0.0063 0.0056 0.0042
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0007 0.002
Plasmodium falciparum glutathione reductase 0.0474 0.0691 0.3322
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0124 0.0149 0.0146
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0109 0.0499
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0126 0.0153 0.0737
Echinococcus granulosus ubiquitin specific protease 41 0.0085 0.0089 0.0129
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0095 0.0105 0.0091
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0126 0.0153 0.0456
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0016 0.0012
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0018 0.0455
Loa Loa (eye worm) CXXC zinc finger family protein 0.0146 0.0185 0.0551
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0426 0.0617 0.1842
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0071 0.0068 0.0099
Chlamydia trachomatis UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminoligase 0.2397 0.3663 0.3632
Trypanosoma brucei hypothetical protein, conserved 0.0126 0.0153 0.0737
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.002 0.0096
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.004 0.0021 0.0029
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0036 0.0014 0.0014
Brugia malayi nuclear hormone receptor family member odr-7 0.0033 0.001 0.003
Schistosoma mansoni glutamate synthase 0.0126 0.0153 0.0226
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0052 0.0039 0.0118
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0126 0.0153 0.0701
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0036 0.0014 0.007
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0426 0.0617 0.1842
Schistosoma mansoni tyrosinase precursor 0.0089 0.0096 0.0141
Echinococcus granulosus Niemann Pick C1 protein 0.0106 0.0121 0.0178
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.003
Trypanosoma cruzi trypanothione reductase, putative 0.0474 0.0691 0.3334
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0103 0.0117 0.0113
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0045 0.0028 0.0117
Entamoeba histolytica hypothetical protein 0.0183 0.0241 0.5934
Brugia malayi Hypothetical tyrosinase-like protein C02C2.1 in chromosome III 0.0089 0.0096 0.0286
Entamoeba histolytica peptidase, C54 family 0.0062 0.0055 0.1353
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0426 0.0617 0.1842
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0104 0.0119 0.0577
Echinococcus granulosus glycine receptor subunit beta 0.0426 0.0617 0.0939
Trichomonas vaginalis ap endonuclease, putative 0.0095 0.0105 0.0484
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.3119 0.4778 0.4775
Brugia malayi Bromodomain containing protein 0.0089 0.0096 0.0288
Mycobacterium tuberculosis Conserved protein 0.0044 0.0027 0.002
Loa Loa (eye worm) mbt repeat family protein 0.0092 0.0101 0.0301
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0097 0.0109 0.0159
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0057 0.0276
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.0406 0.1862
Echinococcus granulosus folylpolyglutamate synthase, mitochondrial 0.0478 0.0697 0.1062
Brugia malayi hypothetical protein 0.0197 0.0262 0.0782
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.003
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0097 0.0109 0.0525
Loa Loa (eye worm) MBCTL1 0.0052 0.0039 0.0118
Echinococcus granulosus dna polymerase eta 0.004 0.002 0.0023
Brugia malayi Glycosyl hydrolases family 31 protein 0.0072 0.007 0.021
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0095 0.0105 0.0099
Loa Loa (eye worm) steroid hormone receptor 0.0071 0.0068 0.0202
Echinococcus granulosus histone acetyltransferase KAT2B 0.0045 0.0028 0.0035
Entamoeba histolytica G protein alpha subunit, putative 0.004 0.0021 0.0506
Mycobacterium ulcerans UDP-N-acetylenolpyruvoylglucosamine reductase 0.6498 1 1
Echinococcus multilocularis GPCR, family 2 0.0483 0.0705 0.0796
Brugia malayi PHD-finger family protein 0.0031 0.0007 0.002
Loa Loa (eye worm) beta-lactamase 0.0438 0.0635 0.1897
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0126 0.0153 0.0226
Echinococcus multilocularis transient receptor potential gamma protein 0.0123 0.0149 0.0163
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0045 0.0028 0.0131
Leishmania major acetyl-CoA synthetase, putative 0.0036 0.0014 0.007
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.1528 0.2319 0.6925
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0474 0.0691 0.3334
Onchocerca volvulus Bile acid receptor homolog 0.0071 0.0068 0.0311
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0001 0.0004
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.004 0.0021 0.0061
Brugia malayi Latrophilin receptor protein 2 0.0483 0.0705 0.2106
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0057 0.0276
Mycobacterium tuberculosis Conserved protein 0.0438 0.0635 0.0629
Toxoplasma gondii thioredoxin reductase 0.1367 0.2071 1
Trypanosoma brucei unspecified product 0.0027 0.0001 0.0004
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0128 0.0157 0.0233
Onchocerca volvulus 0.0104 0.0119 0.0547
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.007 0.0322
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0058 0.0049 0.0234
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.0406 0.1862
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0321 0.0454 0.2194
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0438 0.0635 0.0629
Echinococcus multilocularis dnaJ subfamily B 0.125 0.189 0.2142
Loa Loa (eye worm) hypothetical protein 0.0109 0.0127 0.0378
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0426 0.0617 0.0695
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0045 0.0028 0.0131
Mycobacterium ulcerans glutamate synthase subunit beta 0.0126 0.0153 0.0138
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0126 0.0153 0.0168
Onchocerca volvulus 0.0438 0.0635 0.2917
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0017 0.0083
Echinococcus granulosus fetal alzheimer antigen falz 0.0032 0.0007 0.0003
Echinococcus granulosus cysteine protease atg4b 0.0062 0.0055 0.0076
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0071 0.0068 0.0202
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0102 0.0116 0.0171
Schistosoma mansoni ferritin 0.0103 0.0117 0.0173
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0036 0.0014 0.007
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0036 0.0014 0.0008
Echinococcus granulosus folylpolyglutamate synthase mitochondrial 0.0478 0.0697 0.1062
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0124 0.0149 0.0146
Loa Loa (eye worm) hypothetical protein 0.0197 0.0262 0.0782
Mycobacterium tuberculosis Probable oxidoreductase 0.0044 0.0027 0.002
Echinococcus multilocularis mothers against decapentaplegic 5 0.0149 0.0189 0.0209
Schistosoma mansoni lamin 0.0109 0.0127 0.0187
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0321 0.0454 0.2194
Loa Loa (eye worm) hypothetical protein 0.0426 0.0617 0.1842
Echinococcus multilocularis dna polymerase eta 0.004 0.002 0.0017
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0126 0.0153 0.0701
Echinococcus multilocularis glycine receptor subunit beta 0.0426 0.0617 0.0695
Schistosoma mansoni neurotransmitter gated ion channel 0.0197 0.0262 0.0389
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0028 0.0131
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0071 0.0068 0.0071
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.002 0.0096
Trypanosoma cruzi folylpolyglutamate synthase, putative 0.0478 0.0697 0.3365
Toxoplasma gondii ABC1 family protein 0.0438 0.0635 0.3055
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.016 0.0206 0.0309
Trichomonas vaginalis glutamate synthase, putative 0.0126 0.0153 0.0701
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.004 0.0021 0.0061
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0036 0.0014 0.0356
Mycobacterium leprae THIOREDOXIN TRXC (TRX) (MPT46) 0.0126 0.0153 0.0149
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.004 0.002 0.0017
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0426 0.0617 0.1842
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0033 0.0009 0.0044
Loa Loa (eye worm) glutathione reductase 0.1367 0.2071 0.6185
Echinococcus granulosus guanine nucleotide binding protein subunit 0.004 0.0021 0.0024
Loa Loa (eye worm) acetyltransferase 0.0147 0.0185 0.0553
Mycobacterium ulcerans UDP-N-acetylmuramyl tripeptide synthase 0.0478 0.0697 0.0684
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0092 0.0101 0.0087
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0057 0.0276
Echinococcus multilocularis ecdysone induced protein 78C 0.0071 0.0068 0.0071
Schistosoma mansoni jumonji/arid domain-containing protein 0.0048 0.0033 0.0047
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0085 0.0089 0.0086
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.004 0.002 0.0096
Schistosoma mansoni nAChR subunit 0.0426 0.0617 0.0917
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylmuramoylalanine-D-glutamate ligase 0.1478 0.2242 0.2229
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0474 0.0691 0.0779
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.002 0.0096
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylenolpyruvoylglucosamine reductase 0.6498 1 1
Loa Loa (eye worm) hypothetical protein 0.0092 0.0101 0.0302
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0223 0.1026
Loa Loa (eye worm) hypothetical protein 0.004 0.0021 0.0061
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0033 0.0009 0.0003
Mycobacterium leprae possible oxidoreductase 0.0044 0.0027 0.0023
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0223 0.1026
Loa Loa (eye worm) hypothetical protein 0.0426 0.0617 0.1842
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0071 0.0068 0.0202
Trichomonas vaginalis maltase-glucoamylase, putative 0.0072 0.007 0.0322
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0126 0.0153 0.0146
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.002 0.0096
Echinococcus multilocularis Peptidase C54 0.0062 0.0055 0.0057
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.0017 0.0079
Plasmodium falciparum dihydrofolate synthase/folylpolyglutamate synthase 0.0478 0.0697 0.3354
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0071 0.0068 0.0096
Schistosoma mansoni sulfide quinone reductase 0.0126 0.0153 0.0226
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0071 0.0068 0.0202
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.004 0.0021 0.0017
Plasmodium vivax thioredoxin reductase, putative 0.1367 0.2071 1
Toxoplasma gondii histone lysine methyltransferase SET1 0.029 0.0406 0.1948
Echinococcus granulosus guanine nucleotide binding protein subunit 0.004 0.0021 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.001 0.0044
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0073 0.0072 0.0102
Onchocerca volvulus 0.1115 0.1682 0.7724
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.004 0.0021 0.0024
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0197 0.0262 0.0782
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0092 0.0101 0.0052
Loa Loa (eye worm) hypothetical protein 0.0092 0.0101 0.0301
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.0017 0.0083
Onchocerca volvulus 0.0089 0.0096 0.0439
Brugia malayi hypothetical protein 0.0197 0.0262 0.0782
Trichomonas vaginalis penicillin-binding protein, putative 0.0438 0.0635 0.2917
Loa Loa (eye worm) hypothetical protein 0.051 0.0747 0.2229
Schistosoma mansoni nuclear receptor nhr-48 0.0033 0.001 0.0013
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0085 0.0089 0.0129
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0382 0.0549 0.0835
Trypanosoma cruzi NADH dehydrogenase, putative 0.0126 0.0153 0.0737
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0036 0.0014 0.0011
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0033 0.0009 0.0005
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0937 0.1407 0.2094
Trypanosoma cruzi polo-like protein kinase, putative 0.0097 0.0109 0.0525
Echinococcus multilocularis Niemann Pick C1 protein 0.0106 0.0121 0.0132
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.004 0.0021 0.0029
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0126 0.0153 0.0226
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0126 0.0153 0.0146
Echinococcus multilocularis cysteine protease atg4b 0.0062 0.0055 0.0057
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0197 0.0262 0.0782
Brugia malayi ImpB/MucB/SamB family protein 0.004 0.002 0.0059
Schistosoma mansoni disulfide oxidoreductase 0.0126 0.0153 0.0226
Echinococcus granulosus intermediate filament protein 0.0109 0.0127 0.0187
Loa Loa (eye worm) hypothetical protein 0.023 0.0313 0.0935
Brugia malayi Nuclear hormone receptor E75 0.0033 0.001 0.003
Onchocerca volvulus 0.0196 0.0261 0.1199
Loa Loa (eye worm) hypothetical protein 0.0037 0.0016 0.0048
Mycobacterium ulcerans dehydrogenase 0.0044 0.0027 0.0012
Echinococcus multilocularis zinc finger protein 0.0032 0.0008 0.0003
Trypanosoma brucei DNA polymerase IV, putative 0.004 0.002 0.0096
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0071 0.0068 0.0311
Loa Loa (eye worm) hypothetical protein 0.0071 0.0068 0.0202
Brugia malayi CXXC zinc finger family protein 0.0146 0.0185 0.0551
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0438 0.0635 0.0629
Onchocerca volvulus 0.004 0.0021 0.0094
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0005 0.0008
Echinococcus multilocularis folylpolyglutamate synthase, mitochondrial 0.0478 0.0697 0.0787
Onchocerca volvulus Phospholipase A2 homolog 0.0463 0.0674 0.3094
Echinococcus multilocularis protein patched 0.0045 0.0028 0.0026
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0261 0.0362 0.1082
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0426 0.0617 0.0939
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.004 0.0021 0.0017
Onchocerca volvulus Serine\/threonine kinase homolog 0.0097 0.0109 0.0499
Schistosoma mansoni Smad4 0.0149 0.0189 0.028
Brugia malayi ecdysteroid receptor 0.0071 0.0068 0.0202
Schistosoma mansoni ferritin 0.0103 0.0117 0.0173
Brugia malayi hypothetical protein 0.0033 0.001 0.003
Loa Loa (eye worm) programmed cell death 8 0.0126 0.0153 0.0456
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0126 0.0153 0.0737
Leishmania major AUT2/APG4/ATG4 cysteine peptidase, putative 0.0062 0.0055 0.0265
Loa Loa (eye worm) hypothetical protein 0.0031 0.0007 0.002
Plasmodium falciparum ataxin-2 like protein, putative 0.0207 0.0278 0.1325
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0056 0.0082
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0497 0.0726 0.1106
Brugia malayi F/Y-rich N-terminus family protein 0.0064 0.0056 0.0169
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0497 0.0726 0.0819
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0474 0.0691 0.0677
Leishmania major NADH dehydrogenase, putative 0.0126 0.0153 0.0737
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0036 0.0014 0.0043
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.004 0.0021 0.0094
Leishmania major alkyldihydroxyacetonephosphate synthase 0.0044 0.0027 0.0129
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0071 0.0068 0.0202
Echinococcus granulosus mitogen activated protein kinase 3 0.0104 0.0119 0.0175
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.0119 0.0176
Loa Loa (eye worm) nuclear factor I 0.0083 0.0086 0.0257
Entamoeba histolytica disulphide oxidoreductase, putative 0.0126 0.0153 0.3765
Loa Loa (eye worm) thioredoxin reductase 0.1367 0.2071 0.6185
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0028 0.0128
Treponema pallidum NADH oxidase 0.0474 0.0691 0.0687
Mycobacterium leprae PROBABLE FOLYLPOLYGLUTAMATE SYNTHASE PROTEIN FOLC (FOLYLPOLY-GAMMA-GLUTAMATE SYNTHETASE) (FPGS) 0.1441 0.2185 0.2182
Loa Loa (eye worm) hypothetical protein 0.0197 0.0262 0.0782
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0426 0.0617 0.1842
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0037 0.0016 0.0022
Echinococcus granulosus smad 0.0149 0.0189 0.0283
Entamoeba histolytica acyl-coA synthetase, putative 0.0124 0.0149 0.3684
Loa Loa (eye worm) hypothetical protein 0.0358 0.0511 0.1527
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0085 0.0089 0.0086
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0085 0.0089 0.0432
Echinococcus granulosus glycine receptor subunit alpha 1 0.0426 0.0617 0.0939
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.004 0.0021 0.0094
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0063 0.0056 0.0272
Trypanosoma brucei PAB1-binding protein , putative 0.0207 0.0278 0.134
Loa Loa (eye worm) hypothetical protein 0.0197 0.0262 0.0782
Brugia malayi Common central domain of tyrosinase family protein 0.0089 0.0096 0.0286
Echinococcus multilocularis nAChR subunit 0.0426 0.0617 0.0695
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0045 0.0028 0.0117
Onchocerca volvulus Phospholipase A2 homolog 0.0097 0.0109 0.05
Schistosoma mansoni GTP-binding protein alpha subunit 0.004 0.0021 0.0029
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0126 0.0153 0.3765
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0126 0.0153 0.0721
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0071 0.0068 0.0202
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0197 0.0262 0.0782
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0126 0.0153 0.0721
Brugia malayi Isocitrate dehydrogenase 0.0033 0.0009 0.0027
Trichomonas vaginalis Regulatory protein uhpC, putative 0.0059 0.0049 0.0225
Leishmania major hypothetical protein, conserved 0.0207 0.0278 0.134
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.003
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0474 0.0691 0.3334
Trichomonas vaginalis mercuric reductase, putative 0.0474 0.0691 0.3171
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0109 0.0127 0.0378
Schistosoma mansoni thyroid hormone receptor 0.0199 0.0266 0.0395
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0474 0.0691 0.1027
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0223 0.1026
Treponema pallidum fructose-bisphosphate aldolase 0.0289 0.0406 0.0402
Trichomonas vaginalis glucosylceramidase, putative 0.0172 0.0223 0.1026
Echinococcus multilocularis folylpolyglutamate synthase, mitochondrial 0.0478 0.0697 0.0787
Schistosoma mansoni zinc finger protein 0.0033 0.001 0.0013
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0071 0.0068 0.0202
Loa Loa (eye worm) hypothetical protein 0.0071 0.0068 0.0202
Schistosoma mansoni hypothetical protein 0.0044 0.0026 0.0037
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0126 0.0153 0.0456
Mycobacterium leprae possible ligase 0.0478 0.0697 0.0694
Leishmania major D-lactate dehydrogenase-like protein 0.0044 0.0027 0.0129
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0085 0.0089 0.0432
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0028 0.0136
Schistosoma mansoni chromobox protein 0.0075 0.0074 0.0108
Schistosoma mansoni nAChR subunit 0.0426 0.0617 0.0917
Loa Loa (eye worm) hypothetical protein 0.0426 0.0617 0.1842
Onchocerca volvulus 0.1115 0.1682 0.7724
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0071 0.0068 0.0202
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0085 0.0089 0.0416
Brugia malayi RNA recognition motif domain containing protein 0.0516 0.0755 0.2255
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0474 0.0691 0.3334
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0474 0.0691 0.3334
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0071 0.0068 0.0202
Loa Loa (eye worm) hypothetical protein 0.1115 0.1682 0.5022
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0197 0.0262 0.0782
Mycobacterium tuberculosis Probable dehydrogenase 0.3119 0.4778 0.4775
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0045 0.0028 0.0136
Loa Loa (eye worm) ShTK domain-containing protein 0.0089 0.0096 0.0286
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0103 0.0117 0.011
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0095 0.0105 0.0509
Loa Loa (eye worm) hypothetical protein 0.0092 0.0101 0.0302
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.0406 0.1862
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0036 0.0014 0.0008
Echinococcus granulosus glutamate synthase 0.0126 0.0153 0.0226
Loa Loa (eye worm) hypothetical protein 0.023 0.0313 0.0935
Echinococcus multilocularis ferritin 0.0103 0.0117 0.0127
Schistosoma mansoni hypothetical protein 0.0126 0.0153 0.0226
Echinococcus multilocularis neutral alpha glucosidase AB 0.0072 0.007 0.0074
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0033 0.0009 0.0012
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0074 0.0338
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.004 0.0021 0.0094
Loa Loa (eye worm) hypothetical protein 0.0497 0.0726 0.2167
Brugia malayi hypothetical protein 0.0197 0.0262 0.0782
Schistosoma mansoni hypothetical protein 0.0324 0.0458 0.0681
Loa Loa (eye worm) hypothetical protein 0.0037 0.0015 0.0046
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.0406 0.1862
Brugia malayi nuclear receptor RXR 0.0037 0.0016 0.0048
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0426 0.0617 0.1842
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0071 0.0068 0.0202
Leishmania major 4-coumarate:coa ligase-like protein 0.0124 0.0149 0.0721
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0126 0.0153 0.0226
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0062 0.0055 0.0252
Brugia malayi FAD linked oxidases, C-terminal domain containing protein 0.0044 0.0027 0.008
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0037 0.0016 0.0017
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0201 0.027 0.04
Mycobacterium leprae conserved hypothetical protein 0.0438 0.0635 0.0632
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0058 0.0049 0.0145
Mycobacterium ulcerans esterase/lipase LipP 0.0438 0.0635 0.0622
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.001 0.0044
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0317 0.0448 0.0666
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0067 0.0062 0.0283
Entamoeba histolytica acyl-CoA synthetase, putative 0.0124 0.0149 0.3684
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0074 0.0338
Brugia malayi Inositol-1 0.0038 0.0017 0.0051
Loa Loa (eye worm) hypothetical protein 0.004 0.0021 0.0061
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.1262 0.1909 0.57
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0426 0.0617 0.0917
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprB 0.0126 0.0153 0.0138
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0426 0.0617 0.1842
Trichomonas vaginalis transport proetin, putative 0.0059 0.0049 0.0225
Trypanosoma brucei hypothetical protein, conserved 0.0438 0.0635 0.3067
Loa Loa (eye worm) hypothetical protein 0.1115 0.1682 0.5022
Onchocerca volvulus 0.0146 0.0185 0.0847
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.002 0.0096
Brugia malayi beta-lactamase 0.0438 0.0635 0.1897
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.0017 0.0066
Trichomonas vaginalis conserved hypothetical protein 0.0059 0.0049 0.0225
Plasmodium vivax acetyl-CoA synthetase, putative 0.0036 0.0014 0.0053
Chlamydia trachomatis UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase 0.1441 0.2185 0.2147
Brugia malayi Cytochrome P450 family protein 0.0058 0.0047 0.0141
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0071 0.0068 0.0202
Loa Loa (eye worm) hypothetical protein 0.004 0.002 0.0058
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0474 0.0691 0.3334
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0072 0.007 0.0323
Wolbachia endosymbiont of Brugia malayi NADPH-dependent glutamate synthase beta chain 0.0126 0.0153 0.0136
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.0362 0.1664
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0033 0.001 0.0005
Giardia lamblia Thioredoxin reductase 0.0126 0.0153 0.2136
Trichomonas vaginalis CAMK family protein kinase 0.0097 0.0109 0.0499
Trypanosoma brucei glucosidase, putative 0.0072 0.007 0.0339
Loa Loa (eye worm) hypothetical protein 0.023 0.0313 0.0935
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0147 0.0185 0.0205
Schistosoma mansoni cpg binding protein 0.0157 0.02 0.0297
Trichomonas vaginalis glucarate, hexuronate transporter, putative 0.0059 0.0049 0.0225
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0184 0.0242 0.0359
Schistosoma mansoni nuclear receptor 0.0033 0.001 0.0013
Trichomonas vaginalis glucarate, hexuronate transporter, putative 0.0059 0.0049 0.0225
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0071 0.0068 0.0099
Loa Loa (eye worm) LGC-31 protein 0.0426 0.0617 0.1842
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0072 0.007 0.1732
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.003
Loa Loa (eye worm) hypothetical protein 0.004 0.0021 0.0061
Mycobacterium ulcerans NADPH:adrenodoxin oxidoreductase FprA 0.0126 0.0153 0.0138
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0057 0.0276
Mycobacterium ulcerans hypothetical protein 0.0124 0.0149 0.0135
Loa Loa (eye worm) hypothetical protein 0.0071 0.0068 0.0202
Onchocerca volvulus 0.0036 0.0014 0.0066
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0073 0.0072 0.0076
Onchocerca volvulus 0.0197 0.0262 0.1203
Schistosoma mansoni glutamate synthase 0.0126 0.0153 0.0226
Mycobacterium leprae PROBABLE UDP-N-ACETYLENOLPYRUVOYLGLUCOSAMINE REDUCTASE MURB (UDP-N-ACETYLMURAMATE DEHYDROGENASE) 0.6498 1 1
Brugia malayi Importin beta-1 subunit 0.003 0.0005 0.0015
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0033 0.0009 0.0044
Brugia malayi Nuclear hormone receptor-like 1 0.0037 0.0016 0.0048
Echinococcus granulosus thyroid hormone receptor alpha 0.0033 0.001 0.0007
Brugia malayi Nuclear hormone receptor E75 0.0033 0.001 0.003
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0426 0.0617 0.1842
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0426 0.0617 0.1842
Onchocerca volvulus 0.0197 0.0262 0.1203
Loa Loa (eye worm) hypothetical protein 0.0092 0.0101 0.0302
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0033 0.0009 0.0044
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0085 0.0089 0.0132
Brugia malayi beta-lactamase family protein 0.0438 0.0635 0.1897
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.004 0.0021 0.0061
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0289 0.0406 0.1862
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.004 0.002 0.0028
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.0362 0.1664
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0474 0.0691 0.3334
Echinococcus granulosus zinc finger protein 0.0032 0.0008 0.0004
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0036 0.0014 0.0011
Brugia malayi Intermediate filament tail domain containing protein 0.0109 0.0127 0.0378
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0036 0.0014 0.0008
Brugia malayi Cation transporter family protein 0.0426 0.0617 0.1842
Echinococcus multilocularis cpg binding protein 0.0157 0.02 0.0222
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0043 0.0025 0.003
Mycobacterium ulcerans acyl-CoA synthetase 0.0124 0.0149 0.0135
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0071 0.0068 0.0202
Echinococcus multilocularis lysosomal alpha glucosidase 0.0326 0.0463 0.052
Echinococcus multilocularis expressed protein 0.0103 0.0117 0.0127
Trichomonas vaginalis alpha-glucosidase, putative 0.0072 0.007 0.0322
Schistosoma mansoni family C54 unassigned peptidase (C54 family) 0.0062 0.0055 0.008
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0033 0.001 0.003
Echinococcus multilocularis mothers against decapentaplegic 2 0.0067 0.0062 0.0064
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0014 0.0043
Loa Loa (eye worm) hypothetical protein 0.0197 0.0262 0.0782
Echinococcus granulosus dna polymerase kappa 0.004 0.002 0.0023
Trichomonas vaginalis glutathione reductase, putative 0.0474 0.0691 0.3171
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0033 0.001 0.0005
Echinococcus multilocularis histone acetyltransferase MYST2 0.0052 0.0039 0.0039
Wolbachia endosymbiont of Brugia malayi thioredoxin reductase 0.0126 0.0153 0.0136
Schistosoma mansoni GTP-binding protein alpha subunit 0.004 0.0021 0.0029
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0062 0.0055 0.0252
Plasmodium falciparum acyl-CoA synthetase 0.0092 0.0101 0.0472
Echinococcus granulosus glycine receptor subunit alpha 1 0.0426 0.0617 0.0939
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0033 0.001 0.0046
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0057 0.0276
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.002 0.0096
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0141 0.0177 0.0173
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.001 0.0044
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0028 0.0131
Brugia malayi MH2 domain containing protein 0.0067 0.0062 0.0184
Schistosoma mansoni nAChR subunit 0.0197 0.0262 0.0389
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.004 0.0021 0.0029
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0033 0.0009 0.0027
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0289 0.0406 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.004 0.0118
Echinococcus multilocularis mothers against decapentaplegic 6 0.0067 0.0062 0.0064
Giardia lamblia Sugar transport family protein 0.0059 0.0049 0.062
Toxoplasma gondii NADPH-glutathione reductase 0.0474 0.0691 0.3322
Brugia malayi Hypothetical tyrosinase-like protein F21C3.2 in chromosome I 0.0089 0.0096 0.0286
Schistosoma mansoni survival motor neuron protein 0.0104 0.0119 0.0176
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0937 0.1407 0.2094
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0937 0.1407 0.1593
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.001 0.0044
Echinococcus multilocularis geminin 0.1173 0.1771 0.2008
Echinococcus granulosus ecdysone induced protein 78C 0.0071 0.0068 0.0096
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0001 0.0004
Echinococcus granulosus cpg binding protein 0.0157 0.02 0.03
Mycobacterium tuberculosis Probable UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD 0.1 0.1503 0.1498
Brugia malayi G-protein alpha subunit 0.004 0.0021 0.0061
Mycobacterium ulcerans DNA polymerase IV 0.004 0.002 0.0005
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0071 0.0068 0.0099
Brugia malayi hypothetical protein 0.0197 0.0262 0.0782
Loa Loa (eye worm) hypothetical protein 0.0426 0.0617 0.1842
Loa Loa (eye worm) MH2 domain-containing protein 0.0067 0.0062 0.0184
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0474 0.0691 0.3334
Trichomonas vaginalis ap endonuclease, putative 0.0095 0.0105 0.0484
Schistosoma mansoni nuclear hormone receptor 0.0071 0.0068 0.0099
Schistosoma mansoni sex comb on midleg homolog 0.0102 0.0116 0.0171
Schistosoma mansoni zinc finger protein 0.0032 0.0008 0.001
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0438 0.0635 0.0944
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0087 0.0093 0.0087
Echinococcus granulosus neutral alpha glucosidase AB 0.0072 0.007 0.01
Trypanosoma cruzi DNA polymerase kappa, putative 0.004 0.002 0.0096
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.003 0.0005 0.0021
Brugia malayi chromobox protein homolog 3 0.0042 0.0023 0.0068
Brugia malayi excitatory GABA receptor EXP-1A 0.0426 0.0617 0.1842
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.023 0.0313 0.0935
Loa Loa (eye worm) hypothetical protein 0.0197 0.0262 0.0782
Schistosoma mansoni alpha glucosidase 0.0072 0.007 0.0103
Schistosoma mansoni alpha-glucosidase 0.0281 0.0392 0.0583
Loa Loa (eye worm) hypothetical protein 0.0106 0.0121 0.0362
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0036 0.0014 0.007
Leishmania major trypanothione reductase 0.1367 0.2071 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0438 0.0635 0.2917
Leishmania major hypothetical protein, conserved 0.0126 0.0153 0.0737
Schistosoma mansoni apoferritin-2 0.0103 0.0117 0.0173
Schistosoma mansoni inositol monophosphatase 0.0038 0.0017 0.0024
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.004 0.0021 0.0061
Trypanosoma cruzi hypothetical protein, conserved 0.0126 0.0153 0.0737
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0126 0.0153 0.0701
Loa Loa (eye worm) hypothetical protein 0.0426 0.0617 0.1842
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.002 0.0096
Loa Loa (eye worm) latrophilin receptor protein 2 0.0483 0.0705 0.2106
Trichomonas vaginalis helicase, putative 0.0033 0.001 0.0044
Brugia malayi MH1 domain containing protein 0.0149 0.0189 0.0565
Brugia malayi Glycosyl hydrolases family 31 protein 0.0326 0.0463 0.1381
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0037 0.0016 0.0048
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylmuramyl tripeptide synthase 0.1441 0.2185 0.2172
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0426 0.0617 0.1842
Onchocerca volvulus 0.0089 0.0096 0.0439
Brugia malayi Calcitonin receptor-like protein seb-1 0.1528 0.2319 0.6925
Schistosoma mansoni bromodomain containing protein 0.0077 0.0078 0.0114
Loa Loa (eye worm) hypothetical protein 0.0046 0.0029 0.0086
Mycobacterium tuberculosis Decaprenylphosphoryl-beta-D-ribose 2'-oxidase 0.0044 0.0027 0.002
Schistosoma mansoni microtubule-associated protein tau 0.4246 0.6521 0.971
Brugia malayi Steroid receptor seven-up type 2 0.016 0.0206 0.0616
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0126 0.0153 0.0721
Entamoeba histolytica deoxycytidyl transferase, putative 0.004 0.002 0.0489
Brugia malayi nuclear receptor NHR-88 0.0071 0.0068 0.0202
Echinococcus granulosus lamin dm0 0.0109 0.0127 0.0187
Mycobacterium tuberculosis Possible penicillin-binding protein 0.2798 0.4283 0.4279
Schistosoma mansoni alpha-glucosidase 0.0281 0.0392 0.0583
Loa Loa (eye worm) acetylcholine receptor protein 0.0197 0.0262 0.0782
Echinococcus granulosus transient receptor potential ion channel A 0.0105 0.0121 0.0178
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0045 0.0028 0.0127
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0261 0.0362 0.1082
Loa Loa (eye worm) pigment dispersing factor receptor c 0.1528 0.2319 0.6925
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0126 0.0153 0.0701
Schistosoma mansoni tar DNA-binding protein 0.0516 0.0755 0.1123
Treponema pallidum UDP-N-acetylmuramate--L-alanine ligase 0.4641 0.7131 0.713
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0085 0.0089 0.0432
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0937 0.1407 0.2094
Loa Loa (eye worm) tyrosinase 1 0.0089 0.0096 0.0286
Mycobacterium tuberculosis Probable folylpolyglutamate synthase protein FolC (folylpoly-gamma-glutamate synthetase) (FPGS) 0.1441 0.2185 0.218
Leishmania major DNA polymerase eta, putative 0.004 0.002 0.0096
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0474 0.0691 0.3334
Schistosoma mansoni chromobox protein 0.0075 0.0074 0.0108
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0085 0.0089 0.0129
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0426 0.0617 0.0695
Trypanosoma cruzi trypanothione reductase, putative 0.1367 0.2071 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0095 0.0105 0.0088
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.3119 0.4778 0.4777
Echinococcus granulosus dnaJ subfamily B 0.125 0.189 0.2893
Leishmania major hypothetical protein, conserved 0.0126 0.0153 0.0737
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.0017 0.0018
Schistosoma mansoni aldehyde dehydrogenase 0.0063 0.0056 0.0082
Echinococcus granulosus nAChR subunit 0.0426 0.0617 0.0939
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0071 0.0068 0.0096
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0126 0.0153 0.0737
Entamoeba histolytica thioredoxin reductase, putative 0.0126 0.0153 0.3765
Loa Loa (eye worm) MH2 domain-containing protein 0.2194 0.3349 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.001 0.003
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0052 0.0039 0.0051
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0005 0.0021
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0007 0.0002
Mycobacterium leprae Probable UDP-N-acetylmuramate-alanine ligase MurC 0.2244 0.3426 0.3424
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0018 0.0174
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0036 0.0014 0.0053
Mycobacterium ulcerans acyl-CoA synthetase 0.0124 0.0149 0.0135
Trichomonas vaginalis ferritin, putative 0.0103 0.0117 0.0537
Entamoeba histolytica hypothetical protein 0.0183 0.0241 0.5934
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0071 0.0068 0.0202
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0033 0.001 0.0005
Mycobacterium ulcerans dehydrogenase 0.0126 0.0153 0.0138
Echinococcus granulosus Protein patched homolog 1 0.0045 0.0028 0.0036
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0095 0.0105 0.0509
Brugia malayi AMP-binding enzyme family protein 0.0124 0.0149 0.0446
Mycobacterium ulcerans oxidoreductase 0.0044 0.0027 0.0012
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0426 0.0617 0.1842
Treponema pallidum thioredoxin reductase (trxB) 0.0126 0.0153 0.0149
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.004 0.0021 0.0061
Mycobacterium tuberculosis Possible alkyldihydroxyacetonephosphate synthase AgpS (alkyl-DHAP synthase) (alkylglycerone-phosphate synthase) 0.0044 0.0027 0.002
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0103 0.0117 0.011
Loa Loa (eye worm) hypothetical protein 0.0197 0.0262 0.0782
Schistosoma mansoni ferritin 0.0103 0.0117 0.0173
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0016 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.004 0.002 0.0096
Schistosoma mansoni hypothetical protein 0.0483 0.0705 0.1049
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0103 0.0117 0.01
Brugia malayi MH1 domain containing protein 0.0083 0.0086 0.0257
Mycobacterium leprae Probable oxidoreductase 0.0044 0.0027 0.0023
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.004 0.0021 0.0094
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0095 0.0105 0.1445
Echinococcus multilocularis protein dispatched 1 0.0052 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0052 0.0039 0.0118
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.004 0.0021 0.0094
Trichomonas vaginalis DNA polymerase eta, putative 0.004 0.002 0.0091
Brugia malayi hypothetical protein 0.0197 0.0262 0.0782
Loa Loa (eye worm) hypothetical protein 0.004 0.0021 0.0061
Schistosoma mansoni transient receptor potential channel 4 0.0123 0.0149 0.022
Echinococcus multilocularis musashi 0.0109 0.0127 0.0138
Trypanosoma brucei DNA polymerase eta, putative 0.004 0.002 0.0096
Brugia malayi alkyldihydroxyacetonephosphate synthase 0.0044 0.0027 0.008
Loa Loa (eye worm) hypothetical protein 0.0071 0.0068 0.0202
Brugia malayi MH1 domain containing protein 0.0083 0.0086 0.0257
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0184 0.0242 0.027
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0126 0.0153 0.0701
Brugia malayi AMP-binding enzyme family protein 0.0036 0.0014 0.0043
Echinococcus granulosus peregrin 0.0037 0.0016 0.0016
Mycobacterium ulcerans UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF 0.2397 0.3663 0.3654
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0474 0.0691 0.0675
Echinococcus granulosus glycine receptor subunit beta 0.0426 0.0617 0.0939
Loa Loa (eye worm) hypothetical protein 0.023 0.0313 0.0935
Loa Loa (eye worm) hypothetical protein 0.0062 0.0055 0.0164
Schistosoma mansoni smad1 5 8 and 0.0149 0.0189 0.028
Schistosoma mansoni nAChR subunit 0.0426 0.0617 0.0917
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0426 0.0617 0.0695
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.004 0.0021 0.0094
Schistosoma mansoni hypothetical protein 0.0031 0.0007 0.0008
Echinococcus multilocularis mitogen activated protein kinase 3 0.0104 0.0119 0.013
Brugia malayi orphan nuclear receptor NR2E1 0.0033 0.001 0.003
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0045 0.0028 0.0131
Echinococcus multilocularis snurportin 1 0.0324 0.0458 0.0515
Echinococcus granulosus Niemann Pick C1 protein 0.0151 0.0191 0.0286
Loa Loa (eye worm) hypothetical protein 0.023 0.0313 0.0935
Plasmodium vivax SET domain protein, putative 0.0184 0.0242 0.1155
Trichomonas vaginalis antibiotic synthetase, putative 0.0036 0.0014 0.0066
Echinococcus granulosus survival motor neuron protein 1 0.051 0.0747 0.1138
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0126 0.0153 0.0721
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0126 0.0153 0.0456
Trichomonas vaginalis Clan CA, family C54, ATG4-like cysteine peptidase 0.0062 0.0055 0.0252
Loa Loa (eye worm) heterochromatin protein 1 0.0075 0.0074 0.022
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0474 0.0691 0.2062
Echinococcus multilocularis chromobox protein 1 0.0075 0.0074 0.0078
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0126 0.0153 0.0701
Echinococcus granulosus transient receptor potential gamma protein 0.0123 0.0149 0.022
Loa Loa (eye worm) alkyldihydroxyacetonephosphate synthase 0.0044 0.0027 0.008
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0071 0.0068 0.0071
Trypanosoma cruzi folylpolyglutamate synthetase 0.0478 0.0697 0.3365
Echinococcus multilocularis SAM and MBT domain containing protein 0.0092 0.0101 0.0109
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0095 0.0105 0.0114
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA 0.2992 0.4583 0.4579
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0126 0.0153 0.3765
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0053 0.004 0.0039
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0007 0.0015
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0071 0.0068 0.0096
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.0017 0.0079
Loa Loa (eye worm) nuclear receptor NHR-67 0.0033 0.001 0.003
Brugia malayi AMP-binding enzyme family protein 0.0124 0.0149 0.0446
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0128 0.0157 0.0172
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.004 0.0021 0.0061
Schistosoma mansoni smad 0.0149 0.0189 0.028
Onchocerca volvulus Huntingtin homolog 0.0124 0.015 0.0689
Mycobacterium tuberculosis L-gulono-1,4-lactone dehydrogenase 0.0044 0.0027 0.002
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.3119 0.4778 0.4775
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0438 0.0635 0.0629
Toxoplasma gondii exonuclease III APE 0.0095 0.0105 0.0493
Trypanosoma cruzi NADH dehydrogenase, putative 0.0126 0.0153 0.0737
Toxoplasma gondii bifunctional protein FolC subfamily protein 0.0478 0.0697 0.3354
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.004 0.0021 0.0029
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0126 0.0153 0.0701
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0023 0.0105
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0057 0.0276
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0197 0.0262 0.0782
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0149 0.0189 0.028
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0095 0.0105 0.0154
Mycobacterium ulcerans NADH dehydrogenase Ndh1 0.0126 0.0153 0.0138
Loa Loa (eye worm) jmjC domain-containing protein 0.0048 0.0033 0.0097
Trypanosoma cruzi hypothetical protein, conserved 0.0126 0.0153 0.0737
Trypanosoma cruzi DNA polymerase eta, putative 0.004 0.002 0.0096

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 21.2 nM Binding affinity towards adenosine A2A receptor in rat brain striatum ChEMBL. 11170643
Ki (binding) = 186 nM Binding affinity towards adenosine A1 receptor in rat brain cortex ChEMBL. 11170643

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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