Detailed information for compound 265988

Basic information

Technical information
  • TDR Targets ID: 265988
  • Name: 05270_FLUKA
  • MW: 146.144 | Formula: C5H10N2O3
  • H donors: 2 H acceptors: 3 LogP: -3 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: [O-]C(=O)CNC(=O)C([NH3+])C
  • InChi: 1S/C5H10N2O3/c1-3(6)5(10)7-2-4(8)9/h3H,2,6H2,1H3,(H,7,10)(H,8,9)
  • InChiKey: CXISPYVYMQWFLE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1188-01-8
  • 2-(2-aminopropanoylamino)acetic acid
  • 2-(2-aminopropanoylamino)ethanoic acid
  • 2-(2-ammoniopropanoylamino)acetate
  • 2-(2-azaniumylpropanoylamino)acetate
  • 2-(2-azaniumylpropanoylamino)ethanoate
  • 2-(2-azanylpropanoylamino)ethanoic acid
  • 2-(alanylamino)acetic acid
  • 2-[(2-amino-1-oxopropyl)amino]acetic acid
  • 2-[(2-ammonio-1-oxopropyl)amino]acetate
  • 3997-90-8
  • 687-69-4
  • A0878_SIGMA
  • Ala-Gly
  • alanylglycine
  • D-Alanylglycine
  • EINECS 211-699-9
  • Glycine, N-L-alanyl- (8CI)(9CI)
  • Glycine, N-D-alanyl-
  • Glycine, N-DL-alanyl-
  • Glycine, N-L-alanyl-
  • L-.alpha.-Alanylglycine
  • L-Alanyl-glycine
  • L-Alanylglycine
  • N-DL-Alanylglycine
  • N-L-Alanylglycine
  • NSC 89597
  • NSC522809
  • NSC89597
  • ST5409930

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0017 0.0063 0.0063
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0257 0.022
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0257 0.0628
Entamoeba histolytica cysteine proteinase, putative 0.0243 0.2084 0.5377
Brugia malayi MBOAT family protein 0.0031 0.0193 0.0177
Plasmodium falciparum serine repeat antigen 3 0.0107 0.0872 0.1851
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0473 0.0463
Loa Loa (eye worm) hypothetical protein 0.0031 0.0193 0.0193
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1114 0.9865 1
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0193 0.046
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.051 0.05
Echinococcus multilocularis dnaJ subfamily B 0.0449 0.3926 0.3926
Leishmania major cathepsin L-like protease 0.0442 0.3861 0.3889
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0031 0.0193 0.0182
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0107 0.0872 0.2226
Loa Loa (eye worm) MBOAT family protein 0.0031 0.0193 0.0193
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0473 0.0463
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0219 0.1872 0.1872
Loa Loa (eye worm) hhat protein 0.0031 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.1129 1 1
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0257 0.0628
Echinococcus granulosus cathepsin b 0.1129 1 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0232 0.0232
Trypanosoma cruzi cysteine peptidase, putative 0.0136 0.1125 0.1111
Brugia malayi bZIP transcription factor family protein 0.0078 0.061 0.0596
Trypanosoma cruzi major cysteine proteinase, putative 0.0779 0.6875 0.687
Brugia malayi fibroinase precursor 0.0107 0.0872 0.0857
Schistosoma mansoni hypothetical protein 0.0063 0.048 0.0469
Loa Loa (eye worm) hypothetical protein 0.0017 0.0063 0.0063
Schistosoma mansoni terminal deoxycytidyl transferase 0.0014 0.0041 0.003
Brugia malayi Cathepsin L-like precursor 0.0442 0.3861 0.3852
Mycobacterium ulcerans lipase LipD 0.0036 0.0231 0.7892
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0017 0.0063 0.0048
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0023 0.012 0.012
Brugia malayi beta-lactamase 0.0036 0.0231 0.0216
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0107 0.0872 0.2226
Loa Loa (eye worm) latrophilin receptor protein 2 0.0019 0.0079 0.0079
Trypanosoma cruzi cysteine peptidase, putative 0.1114 0.9865 0.9864
Schistosoma mansoni guanine-nucleotide-exchange-factor 0.0012 0.0016 0.0005
Schistosoma mansoni survival motor neuron protein 0.0048 0.0341 0.033
Trypanosoma cruzi GUP1, putative 0.0031 0.0193 0.0177
Plasmodium falciparum cysteine proteinase falcipain 1 0.0243 0.2084 0.5155
Schistosoma mansoni cathepsin F (C01 family) 0.0306 0.2649 0.2641
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0107 0.0872 0.2226
Echinococcus granulosus FTZ F1 alpha 0.0017 0.0063 0.0063
Onchocerca volvulus 0.0442 0.3861 0.9064
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0031 0.0193 0.0182
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0107 0.0872 0.2226
Trypanosoma cruzi cysteine proteinase, putative 0.0243 0.2084 0.2071
Schistosoma mansoni cathepsin s 0.0136 0.1125 0.1115
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0031 0.0193 0.0472
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0239 0.2048 0.2036
Schistosoma mansoni hypothetical protein 0.0019 0.0079 0.0068
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0473 0.0463
Loa Loa (eye worm) hypothetical protein 0.0026 0.0148 0.0148
Schistosoma mansoni hypothetical protein 0.0048 0.0341 0.033
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0447 0.1132
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0041 0.0025
Trypanosoma cruzi cruzipain precursor, putative 0.0136 0.1125 0.1111
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0231 0.0999
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0138 0.0138
Brugia malayi ImpB/MucB/SamB family protein 0.0014 0.0041 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0107 0.0872 0.2226
Echinococcus granulosus regulator of G protein signaling 7 0.0016 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0019 0.0079 0.0079
Brugia malayi hypothetical protein 0.0016 0.0057 0.0042
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0107 0.0872 0.0862
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0276 0.0279
Schistosoma mansoni cathepsin S (C01 family) 0.0107 0.0872 0.0862
Entamoeba histolytica vacuolar protein sorting 26 0.0031 0.0193 0.046
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0107 0.0872 0.1851
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0107 0.0872 0.2226
Loa Loa (eye worm) hypothetical protein 0.032 0.2776 0.2776
Schistosoma mansoni hypothetical protein 0.0017 0.0064 0.0053
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0243 0.2084 0.2075
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0031 0.0193 0.0193
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0017 0.0063 0.0063
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0017 0.0064 0.012
Brugia malayi steroid hormone receptor 0.0017 0.0063 0.0048
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0231 0.7892
Leishmania major DNA polymerase kappa, putative 0.0021 0.0099 0.0059
Schistosoma mansoni hypothetical protein 0.0086 0.0685 0.0675
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0107 0.0872 0.2148
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0257 0.026
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0017 0.0063 0.0048
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0017 0.0064 0.012
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1129 1 1
Onchocerca volvulus 0.0442 0.3861 0.9064
Schistosoma mansoni hypothetical protein 0.0031 0.0193 0.0182
Echinococcus multilocularis segment polarity protein dishevelled 0.0016 0.0057 0.0057
Brugia malayi cathepsin F-like cysteine proteinase 0.0107 0.0872 0.0857
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0231 0.0106
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0107 0.0872 0.2226
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0036 0.0231 0.0231
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0016 0.0057 0.0098
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0031 0.0193 0.0193
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0473 0.0458
Schistosoma mansoni hypothetical protein 0.0449 0.3926 0.3919
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.3861 1
Schistosoma mansoni lamin 0.0027 0.0152 0.0141
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0257 0.0628
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0231 0.0216
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0107 0.0872 0.0862
Echinococcus granulosus lamin dm0 0.0027 0.0152 0.0152
Leishmania major cathepsin L-like protease 0.1114 0.9865 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0442 0.3861 1
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0193 0.046
Mycobacterium tuberculosis Conserved protein 0.0036 0.0231 0.0999
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0423 0.3695 0.3685
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0031 0.0193 0.0193
Brugia malayi CXXC zinc finger family protein 0.0032 0.0195 0.0179
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0136 0.1125 0.1125
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0017 0.0063 0.0048
Plasmodium vivax vivapain-3 0.0243 0.2084 0.5155
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0341 0.0325
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0031 0.0193 0.0472
Echinococcus granulosus cathepsin b 0.1129 1 1
Entamoeba histolytica cysteine proteinase, putative 0.0243 0.2084 0.5377
Echinococcus granulosus cathepsin l1 0.0306 0.2649 0.2649
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0442 0.3861 0.3861
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0231 0.056
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0017 0.0063 0.0048
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0276 0.0279
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0012 0.0016 0.0005
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0257 0.0242
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0031 0.0193 0.0193
Loa Loa (eye worm) hypothetical protein 0.0017 0.0063 0.0063
Schistosoma mansoni hypothetical protein 0.0019 0.0079 0.0068
Brugia malayi nuclear hormone receptor 0.0017 0.0063 0.0048
Giardia lamblia Cathepsin B precursor 0.0107 0.0872 0.2148
Toxoplasma gondii cathepsin CPC1 0.0107 0.0872 0.2236
Loa Loa (eye worm) ctsf protein 0.0442 0.3861 0.3861
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0016 0.0057 0.0047
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0107 0.0872 0.1851
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0231 0.0233
Brugia malayi hypothetical protein 0.0016 0.0057 0.0042
Echinococcus granulosus sterol O acyltransferase 1 0.032 0.2776 0.2776
Schistosoma mansoni cathepsin F (C01 family) 0.0442 0.3861 0.3855
Echinococcus granulosus cpg binding protein 0.0033 0.0211 0.0211
Echinococcus granulosus dna polymerase kappa 0.0041 0.0276 0.0276
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0107 0.0872 0.2226
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0017 0.0063 0.0048
Brugia malayi nuclear receptor NHR-88 0.0017 0.0063 0.0048
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0017 0.0063 0.0053
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0023 0.012 0.012
Onchocerca volvulus 0.0306 0.2649 0.6207
Entamoeba histolytica cysteine protease, putative 0.0243 0.2084 0.5377
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0442 0.3861 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0276 0.0279
Loa Loa (eye worm) hypothetical protein 0.0486 0.4258 0.4258
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0442 0.3861 0.3861
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0257 0.0628
Schistosoma mansoni hypothetical protein 0.0019 0.0079 0.0068
Schistosoma mansoni hypothetical protein 0.0019 0.0079 0.0068
Onchocerca volvulus 0.0027 0.0152 0.0321
Trypanosoma cruzi cysteine peptidase, putative 0.0243 0.2084 0.2071
Echinococcus granulosus o acyltransferase membrane bound domain 0.0031 0.0193 0.0193
Onchocerca volvulus 0.0036 0.0231 0.0508
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0017 0.0063 0.0053
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0231 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0017 0.0063 0.0053
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0017 0.0063 0.0063
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0119 0.0976 0.0976
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1114 0.9865 1
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0442 0.3861 1
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0031 0.0193 0.0193
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0017 0.0064 0.012
Leishmania major cytochrome p450-like protein 0.0017 0.0064 0.0023
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0199 0.169 0.169
Entamoeba histolytica cysteine protease, putative 0.0107 0.0872 0.2226
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0442 0.3861 1
Trichomonas vaginalis conserved hypothetical protein 0.0107 0.0872 0.2226
Loa Loa (eye worm) hypothetical protein 0.0306 0.2649 0.2649
Echinococcus multilocularis cathepsin b 0.1129 1 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0019 0.0079 0.0063
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0017 0.0063 0.0048
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0017 0.0064 0.012
Brugia malayi Cathepsin L-like precursor 0.0306 0.2649 0.2638
Onchocerca volvulus 0.0486 0.4258 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0017 0.0063 0.0063
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0107 0.0872 0.1851
Brugia malayi Papain family cysteine protease containing protein 0.0107 0.0872 0.0857
Echinococcus granulosus cathepsin L 0.0107 0.0872 0.0872
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0231 0.0221
Schistosoma mansoni dep domain containing protein 0.0016 0.0057 0.0047
Brugia malayi cytochrome P450 0.0017 0.0064 0.0048
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0021 0.0099 0.0059
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0188 0.0189
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0231 0.0221
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.3861 1
Entamoeba histolytica cysteine proteinase, putative 0.0243 0.2084 0.5377
Onchocerca volvulus 0.0442 0.3861 0.9064
Echinococcus multilocularis netrin receptor unc 5 0.0023 0.012 0.012
Loa Loa (eye worm) beta-lactamase 0.0036 0.0231 0.0231
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0017 0.0063 0.0063
Brugia malayi cathepsin L precursor 0.0107 0.0872 0.0857
Loa Loa (eye worm) hypothetical protein 0.0107 0.0872 0.0872
Echinococcus multilocularis cysteine protease 0.0442 0.3861 0.3861
Brugia malayi Cathepsin L-like precursor 0.0442 0.3861 0.3852
Giardia lamblia Cathepsin L precursor 0.0107 0.0872 0.2148
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0276 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0107 0.0872 0.2226
Echinococcus granulosus o acyltransferase membrane bound domain 0.0031 0.0193 0.0193
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0107 0.0872 0.2226
Schistosoma mansoni hypothetical protein 0.0023 0.012 0.011
Loa Loa (eye worm) hypothetical protein 0.0017 0.0063 0.0063
Loa Loa (eye worm) runx1 0.0061 0.0458 0.0458
Loa Loa (eye worm) cytochrome P450 family protein 0.0053 0.0387 0.0387
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0017 0.0063 0.0063
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0017 0.0064 0.0048
Entamoeba histolytica cysteine protease, putative 0.0442 0.3861 1
Brugia malayi hypothetical protein 0.0235 0.201 0.1998
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1114 0.9865 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1114 0.9865 1
Trypanosoma brucei DNA polymerase IV, putative 0.0034 0.0218 0.022
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0306 0.2649 0.6848
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.0221 0.9397
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0306 0.2649 0.6848
Brugia malayi RNA binding protein 0.0063 0.0473 0.0458
Toxoplasma gondii preprocathepsin c precursor, putative 0.0107 0.0872 0.2236
Entamoeba histolytica cysteine protease, putative 0.0243 0.2084 0.5377
Echinococcus granulosus cathepsin L cysteine protease 0.0243 0.2084 0.2084
Schistosoma mansoni RAR-like nuclear receptor 0.0017 0.0063 0.0053
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0107 0.0872 0.1851
Brugia malayi Cathepsin L-like precursor 0.0442 0.3861 0.3852
Leishmania major glycerol uptake protein, putative 0.0031 0.0193 0.0154
Echinococcus granulosus tar DNA binding protein 0.0063 0.0473 0.0473
Loa Loa (eye worm) hypothetical protein 0.0012 0.0024 0.0024
Entamoeba histolytica cysteine protease, putative 0.0243 0.2084 0.5377
Leishmania major glycerol uptake protein, putative 0.0031 0.0193 0.0154
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.3861 1
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0276 0.0279
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1114 0.9865 1
Echinococcus granulosus lamin 0.0027 0.0152 0.0152
Loa Loa (eye worm) hypothetical protein 0.0017 0.0063 0.0063
Schistosoma mansoni sterol O-acyltransferase 1 0.032 0.2776 0.2769
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0017 0.0064 0.012
Echinococcus granulosus cathepsin l cysteine peptidase 0.0442 0.3861 0.3861
Leishmania major hypothetical protein, conserved 0.0031 0.0193 0.0154
Loa Loa (eye worm) hypothetical protein 0.0036 0.0231 0.0231
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0243 0.2084 0.2111
Echinococcus granulosus dna polymerase eta 0.0014 0.0041 0.0041
Schistosoma mansoni zinc finger protein 0.0031 0.0193 0.0182
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0276 0.0279
Echinococcus multilocularis regulator of G protein signaling 7 0.0016 0.0057 0.0057
Brugia malayi follicle stimulating hormone receptor 0.0219 0.1872 0.1859
Loa Loa (eye worm) hypothetical protein 0.0136 0.1125 0.1125
Loa Loa (eye worm) hypothetical protein 0.0036 0.0231 0.0231
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0276 0.0261
Entamoeba histolytica hypothetical protein 0.0036 0.0232 0.0562
Onchocerca volvulus Cathepsin L homolog 0.0442 0.3861 0.9064
Giardia lamblia Cysteine protease 0.0107 0.0872 0.2148
Entamoeba histolytica cysteine protease, putative 0.0243 0.2084 0.5377
Loa Loa (eye worm) hypothetical protein 0.0107 0.0872 0.0872
Brugia malayi latrophilin 2 splice variant baaae 0.004 0.0271 0.0256
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0031 0.0193 0.0193
Brugia malayi hypothetical protein 0.0486 0.4258 0.4249
Loa Loa (eye worm) hypothetical protein 0.0016 0.0057 0.0057
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0442 0.3861 1
Echinococcus granulosus geminin 0.0308 0.2667 0.2667
Brugia malayi ecdysteroid receptor 0.0017 0.0063 0.0048
Loa Loa (eye worm) hypothetical protein 0.0014 0.0041 0.0041
Onchocerca volvulus 0.0036 0.0231 0.0508
Loa Loa (eye worm) hypothetical protein 0.0017 0.0063 0.0063
Onchocerca volvulus 0.0027 0.0152 0.0321
Trypanosoma cruzi DNA polymerase eta, putative 0.0014 0.0041 0.0025
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0017 0.0064 0.0023
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0017 0.0063 0.0063
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0014 0.0041 0.0041
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0017 0.0064 0.012
Plasmodium vivax unspecified product 0.0107 0.0872 0.1851
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1114 0.9865 1
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0031 0.0193 0.046
Leishmania major cathepsin L-like protease 0.0442 0.3861 0.3889
Trypanosoma brucei cysteine peptidase C (CPC) 0.0423 0.3695 0.3745
Leishmania major glycerol uptake protein, putative 0.0031 0.0193 0.0154
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0107 0.0872 0.0862
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0138 0.0122
Echinococcus granulosus rap guanine nucleotide exchange factor 1 0.0012 0.0016 0.0016
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0442 0.3861 1
Echinococcus granulosus son of sevenless 1 0.0012 0.0016 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0107 0.0872 0.2226
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0017 0.0063 0.0053
Echinococcus multilocularis ecdysone induced protein 78C 0.0017 0.0063 0.0063
Echinococcus multilocularis cathepsin L cysteine protease 0.0442 0.3861 0.3861
Schistosoma mansoni dishevelled 0.0016 0.0057 0.0047
Onchocerca volvulus 0.0017 0.0063 0.0112
Brugia malayi hypothetical protein 0.0061 0.0461 0.0446
Echinococcus multilocularis Ankyrin 0.0023 0.0122 0.0122
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0016 0.0057 0.0057
Brugia malayi ImpB/MucB/SamB family protein 0.0014 0.0041 0.0025
Loa Loa (eye worm) fibroinase 0.0442 0.3861 0.3861
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0107 0.0872 0.1851
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0019 0.0079 0.0079
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0232 0.0232
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0442 0.3861 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0017 0.0063 0.0063
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0978 0.8653 0.865
Onchocerca volvulus Cathepsin F homolog 0.0442 0.3861 0.9064
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0276 0.0279
Entamoeba histolytica cysteine proteinase, putative 0.0243 0.2084 0.5377
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0423 0.3695 0.9567
Echinococcus granulosus GPCR family 2 0.0019 0.0079 0.0079
Entamoeba histolytica cysteine protease, putative 0.0243 0.2084 0.5377
Entamoeba histolytica cysteine proteinase, putative 0.0442 0.3861 1
Brugia malayi Cytochrome P450 family protein 0.0025 0.0138 0.0122
Trypanosoma brucei cytochrome P450, putative 0.0025 0.0138 0.0139
Toxoplasma gondii cytochrome p450 superfamily protein 0.0017 0.0064 0.0137
Trypanosoma cruzi major cysteine proteinase, putative 0.0107 0.0872 0.0857
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.3861 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0078 0.061 0.061
Loa Loa (eye worm) cathepsin B 0.0423 0.3695 0.3695
Brugia malayi hypothetical protein 0.0036 0.0232 0.0217
Plasmodium falciparum serine repeat antigen 7 0.0107 0.0872 0.1851
Brugia malayi beta-lactamase family protein 0.0036 0.0231 0.0216
Loa Loa (eye worm) hypothetical protein 0.0031 0.0193 0.0193
Echinococcus multilocularis cathepsin L 0.0107 0.0872 0.0872
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0152 0.0152
Entamoeba histolytica hypothetical protein 0.0031 0.0193 0.046
Brugia malayi polk-prov protein 0.0031 0.0188 0.0172
Brugia malayi Cytochrome P450 family protein 0.0017 0.0064 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.3861 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.3861 1
Brugia malayi Protein kinase domain containing protein 0.0023 0.012 0.0105
Trypanosoma cruzi cysteine protease, putative 0.0243 0.2084 0.2071
Echinococcus multilocularis cathepsin L cysteine protease 0.0442 0.3861 0.3861
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0276 0.0279
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0107 0.0872 0.2226
Brugia malayi Cathepsin L-like precursor 0.0306 0.2649 0.2638
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0473 0.0473
Echinococcus multilocularis ras GTP exchange factor 0.0012 0.0016 0.0016
Onchocerca volvulus 0.0442 0.3861 0.9064
Brugia malayi beta-lactamase family protein 0.0036 0.0231 0.0216
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0231 0.056
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0031 0.0193 0.0193
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0257 0.0257
Schistosoma mansoni ankyrin 23/unc44 0.0023 0.012 0.011
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.0028
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0017 0.0063 0.0063
Entamoeba histolytica cysteine protease, putative 0.0243 0.2084 0.5377
Giardia lamblia Cathepsin L precursor 0.0107 0.0872 0.2148
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0257 0.0242
Schistosoma mansoni cpg binding protein 0.0033 0.0211 0.02
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0017 0.0063 0.0048
Loa Loa (eye worm) hypothetical protein 0.0017 0.0063 0.0063
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0243 0.2084 0.5377
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0017 0.0063 0.0063
Echinococcus granulosus survival motor neuron protein 1 0.0235 0.201 0.201
Trichomonas vaginalis conserved hypothetical protein 0.0107 0.0872 0.2226
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1129 1 1
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0231 0.7892
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0231 0.0216
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0276 0.0279
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0243 0.2084 0.2111
Onchocerca volvulus 0.0107 0.0872 0.2017
Plasmodium falciparum serine repeat antigen 9 0.0107 0.0872 0.1851
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0017 0.0063 0.0063
Echinococcus multilocularis dna polymerase eta 0.0014 0.0041 0.0041
Schistosoma mansoni hypothetical protein 0.0308 0.2667 0.2659
Echinococcus multilocularis Protein lozenge 0.0061 0.0458 0.0458
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0195 0.0195
Loa Loa (eye worm) hypothetical protein 0.0036 0.0231 0.0231
Brugia malayi Papain family cysteine protease containing protein 0.0107 0.0872 0.0857
Brugia malayi N-terminal motif family protein 0.0328 0.2847 0.2836
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0473 0.0473
Echinococcus granulosus segment polarity protein dishevelled 0.0016 0.0057 0.0057
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0276 0.0261
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0473 0.0463
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0031 0.0193 0.046
Leishmania major cathepsin L-like protease 0.0442 0.3861 0.3889
Brugia malayi MBOAT family protein 0.0031 0.0193 0.0177
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0107 0.0872 0.0862
Schistosoma mansoni cathepsin F (C01 family) 0.0442 0.3861 0.3855
Toxoplasma gondii cathepsin CPC2 0.0107 0.0872 0.2236
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0152 0.0136
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0017 0.0064 0.012
Entamoeba histolytica hypothetical protein 0.0036 0.0232 0.0562
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0031 0.0193 0.0193
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0017 0.0064 0.0063
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0107 0.0872 0.1851
Giardia lamblia Cathepsin B precursor 0.0107 0.0872 0.2148
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0442 0.3861 1
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0107 0.0872 0.2148
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0028 0.0028
Loa Loa (eye worm) cysteine protease 0.0442 0.3861 0.3861
Loa Loa (eye worm) hypothetical protein 0.0107 0.0872 0.0872
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0017 0.0063 0.0048
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0107 0.0872 0.0872
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0017 0.0063 0.0063
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0017 0.0063 0.0063
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0017 0.0064 0.012
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0107 0.0872 0.0857
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0017 0.0063 0.0053
Schistosoma mansoni lamin 0.0027 0.0152 0.0141
Brugia malayi intermediate filament protein 0.0027 0.0152 0.0136
Entamoeba histolytica hypothetical protein, conserved 0.0031 0.0193 0.046
Brugia malayi Cytochrome P450 family protein 0.0025 0.0138 0.0122
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0107 0.0872 0.0872
Brugia malayi Steroid receptor seven-up type 2 0.0017 0.0063 0.0048
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0107 0.0872 0.1851
Entamoeba histolytica cysteine protease, putative 0.0107 0.0872 0.2226
Trypanosoma brucei DNA polymerase kappa, putative 0.0031 0.0188 0.0189
Trypanosoma cruzi cruzipain precursor, putative 0.1114 0.9865 0.9864
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0023 0.0122 0.0112
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0107 0.0872 0.2148
Trichomonas vaginalis transmembrane protein nessy, putative 0.0031 0.0193 0.046
Brugia malayi Cathepsin L-like cysteine proteinase 0.0306 0.2649 0.2638
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0107 0.0872 0.2226
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1114 0.9865 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0442 0.3861 1
Brugia malayi regulator of G-protein signaling egl-10 0.0016 0.0057 0.0042
Giardia lamblia Cathepsin L precursor 0.0107 0.0872 0.2148
Echinococcus granulosus ecdysone induced protein 78C 0.0017 0.0063 0.0063
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0442 0.3861 1
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0231 0.0999
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1129 1 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0023 0.012 0.0105
Giardia lamblia Cysteine protease 0.0107 0.0872 0.2148
Loa Loa (eye worm) hypothetical protein 0.0027 0.0152 0.0152
Loa Loa (eye worm) MBOAT family protein 0.0031 0.0193 0.0193
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.3861 1
Loa Loa (eye worm) hypothetical protein 0.0076 0.0591 0.0591
Giardia lamblia Cathepsin L-like protease 0.0107 0.0872 0.2148
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.0257 0.5
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0442 0.3861 0.3861
Brugia malayi POT family protein 0.0049 0.0353 0.0338
Schistosoma mansoni cathepsin B (C01 family) 0.0107 0.0872 0.0862
Echinococcus multilocularis cpg binding protein 0.0033 0.0211 0.0211
Echinococcus multilocularis son of sevenless 1 0.0012 0.0016 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.3861 1
Brugia malayi Hhat protein 0.0031 0.0193 0.0177
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0231 0.0999
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1114 0.9865 1
Giardia lamblia Hypothetical protein 0.0107 0.0872 0.2148
Loa Loa (eye worm) hypothetical protein 0.0289 0.2497 0.2497
Toxoplasma gondii hypothetical protein 0.0031 0.0193 0.0472
Trichomonas vaginalis porcupine, putative 0.0031 0.0193 0.046
Toxoplasma gondii cathepsin B 0.0423 0.3695 0.9568
Loa Loa (eye worm) RNA binding protein 0.0063 0.0473 0.0473
Onchocerca volvulus 0.0442 0.3861 0.9064
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0017 0.0063 0.0048
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0107 0.0872 0.0862
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0017 0.0064 0.012
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0017 0.0063 0.0063
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0059 0.0059
Schistosoma mansoni z-protein (S1r protein) 0.0016 0.0057 0.0047
Echinococcus multilocularis Protein son of sevenless 0.0012 0.0016 0.0016
Echinococcus granulosus Ankyrin 0.0023 0.0122 0.0122
Trypanosoma cruzi glycerol uptake protein, putative 0.0031 0.0193 0.0177
Entamoeba histolytica cysteine protease, putative 0.0107 0.0872 0.2226
Echinococcus multilocularis musashi 0.0027 0.0152 0.0152
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0017 0.0064 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0107 0.0872 0.2226
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0231 0.0216
Onchocerca volvulus Cathepsin L homolog 0.0107 0.0872 0.2017
Schistosoma mansoni ras GTP exchange factor 0.0012 0.0016 0.0005
Loa Loa (eye worm) hypothetical protein 0.0486 0.4258 0.4258
Schistosoma mansoni netrin receptor unc5 0.0023 0.012 0.011
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0107 0.0872 0.0862
Onchocerca volvulus 0.0031 0.0193 0.0417
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0017 0.0064 0.012
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0231 0.0999
Entamoeba histolytica cysteine proteinase 2 0.0243 0.2084 0.5377
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0059 0.0059
Brugia malayi Inositol-1 0.0039 0.0257 0.0242
Loa Loa (eye worm) cytochrome P450 0.0017 0.0064 0.0064
Trypanosoma cruzi glycerol uptake protein, putative 0.0031 0.0193 0.0177
Loa Loa (eye worm) RasGEF domain-containing protein 0.0012 0.0016 0.0016
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0017 0.0063 0.0063
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0231 0.0231
Echinococcus multilocularis regulator of G protein signaling 7 0.0016 0.0057 0.0057
Loa Loa (eye worm) POT family protein 0.0049 0.0353 0.0353
Onchocerca volvulus Protein ultraspiracle homolog 0.0017 0.0063 0.0112
Loa Loa (eye worm) hypothetical protein 0.0017 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0107 0.0872 0.0872
Loa Loa (eye worm) hypothetical protein 0.0012 0.0016 0.0016
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0016 0.0057 0.0042
Entamoeba histolytica hypothetical protein 0.0036 0.0232 0.0562
Brugia malayi TAR-binding protein 0.0063 0.0473 0.0458
Loa Loa (eye worm) CYP4Cod1 0.0025 0.0138 0.0138
Leishmania major glycerol uptake protein, putative 0.0031 0.0193 0.0154
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0017 0.0064 0.0048
Entamoeba histolytica deoxycytidyl transferase, putative 0.0014 0.0041 0.0065
Giardia lamblia Cathepsin B precursor 0.0423 0.3695 1
Entamoeba histolytica membrane-bound O-acyltransferase (MBOAT ) family protein 0.0031 0.0193 0.046
Echinococcus granulosus nuclear factor of activated T cells 5 0.0119 0.0976 0.0976
Brugia malayi Death domain containing protein 0.0023 0.012 0.0105
Onchocerca volvulus Netrin receptor homolog 0.0023 0.012 0.0247
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0107 0.0872 0.2226
Brugia malayi photoreceptor-specific nuclear receptor 0.0017 0.0063 0.0048
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0442 0.3861 1
Plasmodium falciparum serine repeat antigen 4 0.0107 0.0872 0.1851
Entamoeba histolytica cysteine protease, putative 0.0243 0.2084 0.5377
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0231 0.056
Schistosoma mansoni inositol monophosphatase 0.0039 0.0257 0.0247
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0017 0.0064 0.012
Giardia lamblia Cathepsin B precursor 0.0107 0.0872 0.2148
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0031 0.0193 0.0193
Schistosoma mansoni cpg binding protein 0.0033 0.0211 0.02
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0041 0.0041
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0041 0.0276 0.0677
Entamoeba histolytica cysteine protease, putative 0.0243 0.2084 0.5377
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0276 0.0261
Brugia malayi Papain family cysteine protease containing protein 0.0243 0.2084 0.2071
Plasmodium falciparum cysteine proteinase falcipain 3 0.0442 0.3861 1
Plasmodium falciparum serine repeat antigen 5 0.0107 0.0872 0.1851
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0231 0.0231
Entamoeba histolytica cysteine protease, putative 0.0107 0.0872 0.2226
Leishmania major cytochrome p450-like protein 0.0017 0.0064 0.0023
Leishmania major cathepsin L-like protease 0.0442 0.3861 0.3889
Trypanosoma cruzi cysteine proteinase, putative 0.0243 0.2084 0.2071
Echinococcus multilocularis segment polarity protein dishevelled 0.0016 0.0057 0.0057
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0107 0.0872 0.0872
Onchocerca volvulus 0.0061 0.0461 0.1048
Giardia lamblia Cathepsin L precursor 0.0107 0.0872 0.2148
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0086 0.0685 0.0685
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0199 0.169 0.169
Trypanosoma cruzi cytochrome P450, putative 0.0025 0.0138 0.0122
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0473 0.0473
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0276 0.0279
Schistosoma mansoni retinoic acid receptor RXR 0.0017 0.0063 0.0053
Echinococcus granulosus intermediate filament protein 0.0027 0.0152 0.0152
Brugia malayi cathepsin Z-like cysteine proteinase 0.0107 0.0872 0.0857
Echinococcus granulosus regulator of G protein signaling 7 0.0016 0.0057 0.0057
Echinococcus granulosus cathepsin L 0.0243 0.2084 0.2084
Brugia malayi Papain family cysteine protease containing protein 0.0442 0.3861 0.3852
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0017 0.0064 0.012
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0014 0.0041 0.0041
Entamoeba histolytica cysteine protease, putative 0.0107 0.0872 0.2226
Entamoeba histolytica hypothetical protein 0.0036 0.0232 0.0562
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0031 0.0193 0.0182
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0014 0.0041 0.0041
Plasmodium vivax serine-repeat antigen (SERA) 0.0107 0.0872 0.1851
Trichomonas vaginalis DNA polymerase eta, putative 0.0041 0.0276 0.0677
Giardia lamblia Cathepsin B precursor 0.0423 0.3695 1
Entamoeba histolytica cysteine protease, putative 0.0107 0.0872 0.2226
Leishmania major hypothetical protein, conserved 0.0036 0.0231 0.0194
Loa Loa (eye worm) hypothetical protein 0.0107 0.0872 0.0872
Trypanosoma brucei glycerol uptake protein, putative 0.0031 0.0193 0.0194
Brugia malayi cathepsin L-like precursor 0.0306 0.2649 0.2638
Leishmania major glycerol uptake protein, putative 0.0031 0.0193 0.0154
Echinococcus granulosus death domain containing protein 0.0023 0.012 0.012
Loa Loa (eye worm) RasGEF domain-containing protein 0.0012 0.0016 0.0016
Entamoeba histolytica cysteine protease, putative 0.0243 0.2084 0.5377
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0031 0.0193 0.0182
Brugia malayi cathepsin Z-like cysteine proteinase 0.0107 0.0872 0.0857
Loa Loa (eye worm) hypothetical protein 0.004 0.0271 0.0271
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0221 0.0946
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0231 0.056
Schistosoma mansoni hypothetical protein 0.004 0.0271 0.026
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0152 0.0152
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0423 0.3695 0.3688
Schistosoma mansoni cathepsin C 0.0107 0.0872 0.0862
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0017 0.0063 0.0048
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.3861 1
Trichomonas vaginalis esterase, putative 0.0036 0.0231 0.056
Echinococcus multilocularis FTZ F1 alpha 0.0017 0.0063 0.0063
Giardia lamblia Cathepsin L-like protease 0.0107 0.0872 0.2148
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0017 0.0064 0.012
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0231 0.0999
Echinococcus granulosus Protein son of sevenless 0.0012 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0023 0.0122 0.0122
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0107 0.0872 0.2226
Echinococcus granulosus cathepsin l1 0.0442 0.3861 0.3861
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0107 0.0872 0.1851
Schistosoma mansoni steroid hormone receptor ad4bp 0.0017 0.0063 0.0053
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1129 1 1
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0016 0.0057 0.0042
Mycobacterium tuberculosis Conserved protein 0.0036 0.0231 0.0999
Plasmodium falciparum serine repeat antigen 1 0.0107 0.0872 0.1851
Loa Loa (eye worm) hypothetical protein 0.0036 0.0231 0.0231
Schistosoma mansoni nuclear hormone receptor 0.0017 0.0063 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.3861 1
Trypanosoma cruzi GUP1, putative 0.0031 0.0193 0.0177
Schistosoma mansoni DNA polymerase eta 0.0014 0.0041 0.003
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0031 0.0193 0.0193
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0328 0.2847 0.6674
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0107 0.0872 0.1851
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0031 0.0193 0.0193
Schistosoma mansoni intermediate filament proteins 0.0027 0.0152 0.0141
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0017 0.0063 0.0063
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0017 0.0063 0.0063
Leishmania major cathepsin L-like protease 0.0442 0.3861 0.3889
Brugia malayi MBOAT family protein 0.0031 0.0193 0.0177
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0243 0.2084 0.5377
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.3861 1
Trypanosoma brucei glycerol uptake protein, putative 0.0031 0.0193 0.0194
Entamoeba histolytica cysteine protease, putative 0.0243 0.2084 0.5377
Entamoeba histolytica cysteine protease, putative 0.0243 0.2084 0.5377
Loa Loa (eye worm) steroid hormone receptor 0.0017 0.0063 0.0063
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0017 0.0064 0.012
Leishmania major cathepsin L-like protease 0.1114 0.9865 1
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0136 0.1125 0.1111
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0017 0.0064 0.012
Echinococcus multilocularis cysteine protease 0.0442 0.3861 0.3861
Plasmodium vivax serine-repeat antigen (SERA) 0.0107 0.0872 0.1851
Schistosoma mansoni dishevelled 0.0016 0.0057 0.0047
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0423 0.3695 0.372
Trypanosoma brucei DNA polymerase kappa, putative 0.0021 0.0099 0.0099
Brugia malayi Calcitonin receptor-like protein seb-1 0.0059 0.0437 0.0422
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0059 0.0437 0.0437
Loa Loa (eye worm) hypothetical protein 0.0031 0.0188 0.0188
Treponema pallidum alginate O-acetylation protein (algI) 0.0031 0.0193 0.5
Loa Loa (eye worm) DIX domain-containing protein 0.0016 0.0057 0.0057
Onchocerca volvulus 0.0032 0.0195 0.0421
Echinococcus multilocularis lamin dm0 0.0027 0.0152 0.0152
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0017 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0036 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.0016 0.0057 0.0057
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.3861 1
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0031 0.0193 0.0193
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1114 0.9865 1
Onchocerca volvulus 0.0442 0.3861 0.9064
Loa Loa (eye worm) RasGEF domain-containing protein 0.0012 0.0016 0.0016
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0243 0.2084 0.2075
Echinococcus multilocularis sterol O acyltransferase 1 0.032 0.2776 0.2776
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0257 0.0257
Echinococcus multilocularis lamin 0.0027 0.0152 0.0152
Schistosoma mansoni hypothetical protein 0.0308 0.2667 0.2659
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0231 0.0999
Schistosoma mansoni hypothetical protein 0.0036 0.0232 0.0221
Brugia malayi Papain family cysteine protease containing protein 0.0243 0.2084 0.2071
Schistosoma mansoni thyroid hormone receptor 0.0103 0.0835 0.0826
Plasmodium vivax vivapain-1 0.0243 0.2084 0.5155
Loa Loa (eye worm) hypothetical protein 0.0016 0.0057 0.0057
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0228 0.1947 1
Onchocerca volvulus Bile acid receptor homolog 0.0017 0.0063 0.0112
Brugia malayi Cathepsin L-like precursor 0.0442 0.3861 0.3852
Loa Loa (eye worm) hypothetical protein 0.0328 0.2847 0.2847
Plasmodium vivax unspecified product 0.0136 0.1125 0.2541
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0031 0.0193 0.0193
Echinococcus multilocularis thyroid hormone receptor alpha 0.0103 0.0835 0.0835
Onchocerca volvulus 0.0016 0.0057 0.0098
Schistosoma mansoni cpg binding protein 0.0032 0.0195 0.0184
Mycobacterium ulcerans hypothetical protein 0.0036 0.0231 0.7892
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0231 0.0999
Toxoplasma gondii hypothetical protein 0.0016 0.0057 0.012
Giardia lamblia Cathepsin B precursor 0.0107 0.0872 0.2148
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0193 0.046
Loa Loa (eye worm) hypothetical protein 0.0017 0.0063 0.0063
Entamoeba histolytica cysteine proteinase, putative 0.0442 0.3861 1
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0107 0.0872 0.1851
Echinococcus granulosus o acyltransferase membrane bound domain 0.0031 0.0193 0.0193
Echinococcus granulosus cysteine protease 0.0243 0.2084 0.2084
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0276 0.0279
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0232 0.0221
Echinococcus multilocularis dna polymerase kappa 0.0041 0.0276 0.0276
Echinococcus granulosus Pleckstrin G protein interacting region 0.0016 0.0057 0.0057
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0107 0.0872 0.2226
Giardia lamblia Cysteine protease 0.0107 0.0872 0.2148
Entamoeba histolytica cysteine protease, putative 0.0243 0.2084 0.5377
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0021 0.0099 0.0306
Brugia malayi Cathepsin L-like precursor 0.0442 0.3861 0.3852
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0017 0.0063 0.0063
Mycobacterium ulcerans DNA polymerase IV 0.0041 0.0276 1
Trypanosoma cruzi cysteine peptidase, putative 0.0442 0.3861 0.3852
Loa Loa (eye worm) hypothetical protein 0.0306 0.2649 0.2649
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0031 0.0193 0.0182
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0231 0.056
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.3861 1
Giardia lamblia Cathepsin L precursor 0.0107 0.0872 0.2148
Trypanosoma cruzi cysteine peptidase, putative 0.1114 0.9865 0.9864
Brugia malayi cathepsin F-like cysteine proteinase 0.0136 0.1125 0.1111
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0276 0.0279
Loa Loa (eye worm) hypothetical protein 0.0136 0.1125 0.1125
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0017 0.0063 0.0053
Brugia malayi Nuclear hormone receptor-like 1 0.0017 0.0063 0.0048
Echinococcus multilocularis GPCR, family 2 0.0019 0.0079 0.0079
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0078 0.061 0.061
Schistosoma mansoni regulator of G protein signaling 0.0016 0.0057 0.0047
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0442 0.3861 1
Echinococcus granulosus ras GTP exchange factor 0.0012 0.0016 0.0016
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0017 0.0063 0.0048
Echinococcus multilocularis 0.0017 0.0064 0.0064
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0107 0.0872 0.0862
Loa Loa (eye worm) hypothetical protein 0.0136 0.1125 0.1125
Entamoeba histolytica cysteine proteinase, putative 0.0306 0.2649 0.6848
Brugia malayi Cathepsin L-like precursor 0.0136 0.1125 0.1111
Leishmania major cathepsin L-like protease 0.1114 0.9865 1
Trypanosoma cruzi glycerol uptake protein, putative 0.0031 0.0193 0.0177
Loa Loa (eye worm) hypothetical protein 0.0012 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0239 0.2048 0.2048
Brugia malayi MBOAT family protein 0.0031 0.0193 0.0177
Brugia malayi Papain family cysteine protease containing protein 0.0107 0.0872 0.0857
Schistosoma mansoni thyroid hormone receptor 0.0103 0.0835 0.0826
Giardia lamblia Cathepsin B precursor 0.0423 0.3695 1
Brugia malayi Cytochrome P450 family protein 0.0053 0.0387 0.0371
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.0257 0.9116
Echinococcus granulosus dnaJ subfamily B 0.0449 0.3926 0.3926
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0442 0.3861 0.3861
Loa Loa (eye worm) MBOAT family protein 0.0031 0.0193 0.0193
Echinococcus granulosus cathepsin L cysteine proteinase 0.0442 0.3861 0.3861
Loa Loa (eye worm) inositol-1 0.0039 0.0257 0.0257
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0086 0.0685 0.0685
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0257 0.064
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0017 0.0063 0.0048
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0023 0.012 0.012
Schistosoma mansoni cytochrome P450 0.0017 0.0064 0.0053
Entamoeba histolytica hypothetical protein 0.0107 0.0872 0.2226
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0017 0.0063 0.0112
Loa Loa (eye worm) hhat protein 0.0031 0.0193 0.0193
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0031 0.0193 0.0193
Onchocerca volvulus 0.0036 0.0231 0.0508
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0012 0.0016 0.0005
Echinococcus multilocularis survival motor neuron protein 1 0.0235 0.201 0.201
Echinococcus multilocularis jun protein 0.0078 0.061 0.061
Entamoeba histolytica cysteine proteinase 1, putative 0.0243 0.2084 0.5377
Echinococcus multilocularis cathepsin b 0.1129 1 1
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0017 0.0064 0.012
Schistosoma mansoni lozenge 0.0061 0.0458 0.0448
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0019 0.0079 0.0079
Echinococcus granulosus netrin receptor unc 5 0.0023 0.012 0.012
Giardia lamblia Encystation-specific protease 0.0107 0.0872 0.2148
Loa Loa (eye worm) hypothetical protein 0.0306 0.2649 0.2649
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0442 0.3861 1
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0231 0.0231
Mycobacterium ulcerans beta-lactamase 0.0036 0.0231 0.7892
Plasmodium vivax vivapain-2 0.0442 0.3861 1
Plasmodium vivax unspecified product 0.0243 0.2084 0.5155
Toxoplasma gondii cathepsin CPL 0.0442 0.3861 1
Entamoeba histolytica cysteine protease, putative 0.0243 0.2084 0.5377
Leishmania major cytochrome p450-like protein 0.0025 0.0138 0.0099
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0276 0.0261
Loa Loa (eye worm) cytochrome P450 family protein 0.0025 0.0138 0.0138
Schistosoma mansoni coup transcription factor 0.0017 0.0063 0.0053
Echinococcus granulosus rap guanine nucleotide exchange factor 6 0.0012 0.0016 0.0016
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0031 0.0193 0.0182
Leishmania major cysteine peptidase A (CPA) 0.0442 0.3861 0.3889
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0017 0.0064 0.012
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0107 0.0872 0.2226
Brugia malayi Uncoordinated protein 44 0.0023 0.012 0.0105
Echinococcus granulosus cytochrome P450 2K1 0.0017 0.0064 0.0064
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0025 0.0138 0.3491
Loa Loa (eye worm) hypothetical protein 0.0031 0.0193 0.0193
Echinococcus multilocularis cathepsin L 0.0243 0.2084 0.2084
Onchocerca volvulus 0.0442 0.3861 0.9064
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0107 0.0872 0.1851
Mycobacterium tuberculosis Conserved protein 0.0036 0.0231 0.0999
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0107 0.0872 0.2148
Echinococcus multilocularis geminin 0.0308 0.2667 0.2667
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0031 0.0193 0.0193
Echinococcus granulosus segment polarity protein dishevelled 0.0016 0.0057 0.0057
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1114 0.9865 1
Echinococcus multilocularis rap guanine nucleotide exchange factor 1 0.0012 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0235 0.201 0.201
Brugia malayi DIX domain containing protein 0.0016 0.0057 0.0042
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0059 0.0059
Echinococcus granulosus jun protein 0.0078 0.061 0.061
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0442 0.3861 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1114 0.9865 1
Brugia malayi Latrophilin receptor protein 2 0.0019 0.0079 0.0063
Trypanosoma brucei DNA polymerase eta, putative 0.0014 0.0041 0.004
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0017 0.0064 0.012
Echinococcus multilocularis rap guanine nucleotide exchange factor 6 0.0012 0.0016 0.0016
Toxoplasma gondii ABC1 family protein 0.0036 0.0231 0.0572
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0243 0.2084 0.2071
Trypanosoma cruzi cysteine peptidase, putative 0.1114 0.9865 0.9864
Loa Loa (eye worm) hypothetical protein 0.0023 0.012 0.012
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0017 0.0063 0.0048
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0107 0.0872 0.0862
Loa Loa (eye worm) hypothetical protein 0.0442 0.3861 0.3861
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1129 1 1
Mycobacterium leprae Probable lipase LipE 0.0036 0.0231 1
Plasmodium falciparum serine repeat antigen 6 0.0107 0.0872 0.1851
Plasmodium falciparum serine repeat antigen 2 0.0107 0.0872 0.1851
Schistosoma mansoni ras GTP exchange factor son of sevenless 0.0012 0.0016 0.0005
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0107 0.0872 0.0862
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0028 0.0028
Brugia malayi Cathepsin L-like precursor 0.0442 0.3861 0.3852
Giardia lamblia Cathepsin B precursor 0.0107 0.0872 0.2148
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0016 0.0057 0.0057
Trypanosoma brucei unspecified product 0.0034 0.0218 0.022
Loa Loa (eye worm) hypothetical protein 0.0107 0.0872 0.0872
Onchocerca volvulus 0.0048 0.0341 0.0766
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0017 0.0063 0.0063
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0014 0.0041 0.003
Plasmodium falciparum serine repeat antigen 8 0.0107 0.0872 0.1851
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0107 0.0872 0.1851
Brugia malayi cathepsin L-like cysteine proteinase 0.0107 0.0872 0.0857
Giardia lamblia Cathepsin L precursor 0.0107 0.0872 0.2148
Onchocerca volvulus Cathepsin L homolog 0.0442 0.3861 0.9064
Brugia malayi MBOAT family protein 0.0031 0.0193 0.0177
Schistosoma mansoni inositol monophosphatase 0.0039 0.0257 0.0247
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0107 0.0872 0.2226
Giardia lamblia Cysteine protease 0.0107 0.0872 0.2148
Giardia lamblia Hypothetical protein 0.0107 0.0872 0.2148
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0107 0.0872 0.1851
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0017 0.0064 0.012
Brugia malayi diacylglycerol acyltransferase 0.0031 0.0193 0.0177
Plasmodium vivax vivapain-2 0.0442 0.3861 1
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0017 0.0064 0.012
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0473 0.0463
Schistosoma mansoni jun-related protein 0.0063 0.048 0.0469
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0243 0.2084 0.2075

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 0.14 mM Inhibition constant (Ki) for human intestinal peptide carrier ChEMBL. 14667225
Log 1/T (functional) NB 0 Bitter threshold value; NB denotes 'Not bitter' ChEMBL. 3656360
logP (ADMET) = 3.61 Partition coefficient (logP) ChEMBL. 3656360

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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