Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0153 | 0.0228 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0021 | 0.0035 | 0.1148 |
Brugia malayi | Protein kinase domain containing protein | 0.1089 | 0.6587 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.004 | 0.0156 | 0.5086 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0208 | 0.0311 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0059 | 0.0268 | 0.0402 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0056 | 0.0254 | 0.8297 |
Schistosoma mansoni | lipoxygenase | 0.0081 | 0.0405 | 0.0616 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0024 | 0.0057 | 0.1872 |
Plasmodium vivax | holo-[acyl-carrier-protein] synthase, putative | 0.0023 | 0.0049 | 0.092 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0065 | 0.0306 | 0.0461 |
Mycobacterium ulcerans | DNA polymerase IV | 0.004 | 0.0156 | 0.0125 |
Giardia lamblia | DINP protein human, muc B family | 0.0021 | 0.0035 | 0.0111 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0017 | 0.0014 | 0.0017 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0056 | 0.0254 | 0.0375 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.004 | 0.0156 | 0.5086 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0036 | 0.0051 |
Echinococcus granulosus | serine protein kinase ATM | 0.0024 | 0.0057 | 0.0083 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0082 | 0.041 | 0.0618 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0003 | 0.0004 |
Leishmania major | target of rapamycin (TOR) kinase 2, putative | 0.0018 | 0.0017 | 0.0547 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0019 | 0.0027 | 0.0037 |
Onchocerca volvulus | 0.0465 | 0.2761 | 0.4167 | |
Mycobacterium ulcerans | bifunctional penicillin-binding protein 1A/1B PonA1 | 0.0763 | 0.4592 | 0.5308 |
Mycobacterium ulcerans | DNA polymerase IV | 0.004 | 0.0156 | 0.0125 |
Brugia malayi | glutaminase DH11.1 | 0.0269 | 0.1557 | 0.2361 |
Loa Loa (eye worm) | CAMK/PIM protein kinase | 0.1089 | 0.6587 | 1 |
Mycobacterium tuberculosis | Probable bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 (murein polymerase) [includes: penicillin-insen | 0.0526 | 0.3134 | 0.5305 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0059 | 0.0268 | 0.0406 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0018 | 0.0017 | 0.0021 |
Brugia malayi | PHD-finger family protein | 0.0024 | 0.0058 | 0.0083 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0156 | 0.1989 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0003 | 0.0004 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0021 | 0.0036 | 0.119 |
Mycobacterium ulcerans | fructose-bisphosphate aldolase | 0.014 | 0.0769 | 0.0842 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0056 | 0.0254 | 0.0382 |
Loa Loa (eye worm) | doublecortin family protein | 0.0019 | 0.0027 | 0.0037 |
Echinococcus multilocularis | phosphatidylinositol 3 and 4 kinase | 0.0018 | 0.0017 | 0.0021 |
Giardia lamblia | Fructose-bisphosphate aldolase | 0.0287 | 0.1671 | 1 |
Onchocerca volvulus | Serine\/threonine protein kinase homolog | 0.1089 | 0.6587 | 1 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0024 | 0.0057 | 0.0083 |
Trypanosoma brucei | RNA helicase, putative | 0.0143 | 0.0783 | 1 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0082 | 0.041 | 0.0622 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0287 | 0.1671 | 0.163 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.0208 | 0.0311 |
Echinococcus multilocularis | proto oncogene serine:threonine protein kinase | 0.1089 | 0.6587 | 1 |
Trypanosoma brucei | phosphatidylinositol 3-kinase, putative | 0.0018 | 0.0017 | 0.0214 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.0032 | 0.0044 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0032 | 0.0049 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0287 | 0.1671 | 0.3616 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0027 | 0.0037 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0019 | 0.0027 | 0.0037 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0018 | 0.0017 | 0.0547 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0059 | 0.0268 | 1 |
Leishmania major | phosphatidylinositol 3-related kinase, putative | 0.0018 | 0.0017 | 0.0547 |
Echinococcus multilocularis | muscleblind protein | 0.0146 | 0.0806 | 0.1219 |
Mycobacterium leprae | PROBABLE BIFUNCTIONAL MEMBRANE-ASSOCIATED PENICILLIN-BINDING PROTEIN 1A/1B PONA2 (MUREIN POLYMERASE) [INCLUDES: PENICILLIN-INSEN | 0.0526 | 0.3134 | 0.5294 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0065 | 0.0306 | 1 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0019 | 0.0027 | 0.0037 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0065 | 0.0306 | 0.0461 |
Schistosoma mansoni | glutaminase | 0.0269 | 0.1557 | 0.2364 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0075 | 0.037 | 0.0562 |
Treponema pallidum | penicillin-binding protein (pbp-2) | 0.0763 | 0.4592 | 0.4565 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0124 | 0.0184 |
Loa Loa (eye worm) | phosphatidylinositol 3 | 0.0018 | 0.0017 | 0.0021 |
Mycobacterium tuberculosis | Probable penicillin-binding membrane protein PbpB | 0.0444 | 0.2634 | 0.4449 |
Trichomonas vaginalis | set domain proteins, putative | 0.0465 | 0.2761 | 0.5997 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0164 | 0.0245 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0287 | 0.1671 | 0.3616 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0056 | 0.0254 | 0.0386 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.004 | 0.0156 | 0.5086 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0156 | 0.1989 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.0208 | 0.0311 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.0806 | 0.1219 |
Echinococcus granulosus | phosphatidylinositol 3 and 4 kinase | 0.0018 | 0.0017 | 0.0021 |
Echinococcus granulosus | dna polymerase kappa | 0.004 | 0.0156 | 0.0232 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0027 | 0.0037 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0034 | 0.0116 | 0.1481 |
Leishmania major | phosphatidylinositol kinase related protein, putative | 0.0018 | 0.0017 | 0.0554 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0146 | 0.0806 | 0.1219 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0017 | 0.0011 | 0.0012 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0011 | 0.0016 |
Schistosoma mansoni | hypothetical protein | 0.0143 | 0.0783 | 0.1189 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0156 | 0.1989 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.0208 | 0.0311 |
Leishmania major | target of rapamycin kinase (TOR) kinase 3 | 0.0018 | 0.0017 | 0.0547 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0156 | 0.1989 |
Leishmania major | phosphatidylinositol 3-kinase, putative | 0.0018 | 0.0017 | 0.0547 |
Trypanosoma brucei | phosphatidylinositol kinase related protein, putative | 0.0024 | 0.0057 | 0.0732 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0017 | 0.0011 | 0.0012 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.004 | 0.0156 | 0.1989 |
Schistosoma mansoni | lipoxygenase | 0.0116 | 0.062 | 0.0941 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0156 | 0.1989 |
Entamoeba histolytica | hypothetical protein | 0.0024 | 0.0057 | 0.0245 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0038 | 0.0139 | 0.0206 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0156 | 0.1989 |
Wolbachia endosymbiont of Brugia malayi | cell division protein FtsI | 0.1645 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.0806 | 0.1219 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0035 | 0.0124 | 0.0184 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0065 | 0.0306 | 1 |
Toxoplasma gondii | FATC domain-containing protein | 0.0024 | 0.0057 | 0.1619 |
Mycobacterium ulcerans | bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 | 0.0526 | 0.3134 | 0.3605 |
Echinococcus granulosus | RUN | 0.0019 | 0.0027 | 0.0037 |
Entamoeba histolytica | hypothetical protein | 0.0023 | 0.0049 | 0.0196 |
Schistosoma mansoni | phosphatidylinositol 3-and 4-kinase | 0.0018 | 0.0017 | 0.0025 |
Brugia malayi | Doublecortin family protein | 0.0019 | 0.0027 | 0.0037 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1089 | 0.6587 | 1 |
Loa Loa (eye worm) | glutaminase 2 | 0.0269 | 0.1557 | 0.2361 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0156 | 0.1989 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0287 | 0.1671 | 0.3616 |
Treponema pallidum | penicillin-binding protein (pbp-3) | 0.1418 | 0.8607 | 0.86 |
Brugia malayi | Pre-SET motif family protein | 0.0059 | 0.0268 | 0.0402 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0027 | 0.0037 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0065 | 0.0306 | 0.175 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0056 | 0.0254 | 0.0382 |
Brugia malayi | Serine/threonine-protein kinase Pim-3 | 0.1089 | 0.6587 | 1 |
Mycobacterium leprae | PROBABLE BIFUNCTIONAL PENICILLIN-BINDING PROTEIN 1A/1B PONA1 (MUREIN POLYMERASE) (PBP1): PENICILLIN-INSENSITIVE TRANSGLYCOSYLASE | 0.0763 | 0.4592 | 0.7795 |
Brugia malayi | Muscleblind-like protein | 0.0146 | 0.0806 | 0.1219 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0096 | 0.0141 |
Leishmania major | phosphopantetheinyl transferase-like protein | 0.0023 | 0.0049 | 0.1604 |
Mycobacterium ulcerans | penicillin-binding membrane protein PbpB | 0.1418 | 0.8607 | 1 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0287 | 0.1671 | 0.3616 |
Echinococcus multilocularis | dna polymerase kappa | 0.004 | 0.0156 | 0.0232 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0113 | 0.0167 |
Mycobacterium ulcerans | glutaminase | 0.0269 | 0.1557 | 0.1762 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0056 | 0.0254 | 0.0382 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0016 | 0.0008 | 0.0103 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase superfamily protein | 0.0023 | 0.0049 | 0.1291 |
Echinococcus multilocularis | zinc finger protein | 0.0019 | 0.0026 | 0.0035 |
Plasmodium vivax | SET domain protein, putative | 0.0059 | 0.0268 | 1 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0022 | 0.0044 | 0.0062 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0065 | 0.0306 | 0.0461 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0116 | 0.062 | 0.0937 |
Schistosoma mansoni | hypothetical protein | 0.0019 | 0.0027 | 0.0041 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0065 | 0.0306 | 0.0465 |
Schistosoma mansoni | polycystin 1-related | 0.0019 | 0.0027 | 0.0041 |
Mycobacterium leprae | Probable penicillin-binding membrane protein PbpB | 0.0444 | 0.2634 | 0.4436 |
Echinococcus multilocularis | RUN | 0.0019 | 0.0027 | 0.0037 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0763 | 0.4592 | 1 |
Mycobacterium leprae | Probable fructose bisphosphate aldolase Fba | 0.014 | 0.0769 | 0.1236 |
Trypanosoma brucei | phosphatidylinositol 4-kinase, putative | 0.0018 | 0.0017 | 0.0214 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0139 | 0.0206 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0065 | 0.0306 | 1 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.004 | 0.0156 | 0.0304 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm) | 0.0024 | 0.0057 | 0.0087 |
Trypanosoma brucei | Phosphatidylinositol 3-kinase tor1 | 0.0018 | 0.0017 | 0.0214 |
Brugia malayi | polk-prov protein | 0.0031 | 0.0096 | 0.0141 |
Schistosoma mansoni | loxhd1 | 0.0019 | 0.0027 | 0.0041 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0031 | 0.0096 | 0.122 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0016 | 0.0008 | 0.0103 |
Mycobacterium tuberculosis | Possible penicillin-binding lipoprotein | 0.0301 | 0.1757 | 0.2948 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0018 | 0.0017 | 0.0554 |
Echinococcus multilocularis | FKBP12 rapamycin complex associated protein | 0.0018 | 0.0017 | 0.0021 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0003 | 0.0004 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0038 | 0.0139 | 0.0206 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0287 | 0.1671 | 0.3616 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0018 | 0.0017 | 0.0021 |
Echinococcus multilocularis | serine protein kinase ATM | 0.0024 | 0.0057 | 0.0083 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0058 | 0.0267 | 0.0401 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0287 | 0.1671 | 1 |
Trypanosoma brucei | target of rapamycin kinase 3, putative | 0.0018 | 0.0017 | 0.0214 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0016 | 0.0008 | 0.0103 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0011 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0113 | 0.0167 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0021 | 0.0035 | 0.0449 |
Treponema pallidum | penicillin-binding protein (pbp-1) | 0.1645 | 1 | 1 |
Mycobacterium leprae | POSSIBLE PENICILLIN-BINDING LIPOPROTEIN | 0.0301 | 0.1757 | 0.2931 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0059 | 0.0268 | 0.0406 |
Brugia malayi | Pre-SET motif family protein | 0.0408 | 0.2414 | 0.3662 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm)-related | 0.0018 | 0.0017 | 0.0025 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.0138 | 0.0206 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0065 | 0.0306 | 0.0461 |
Trichomonas vaginalis | PIKK family atypical protein kinase | 0.0024 | 0.0057 | 0.0089 |
Trichomonas vaginalis | glutaminase, putative | 0.0269 | 0.1557 | 0.3367 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0019 | 0.0027 | 0.0037 |
Schistosoma mansoni | zinc finger protein | 0.0019 | 0.0026 | 0.0039 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0022 | 0.0044 | 0.0062 |
Mycobacterium ulcerans | penicillin-binding protein PbpA | 0.0973 | 0.5876 | 0.681 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0113 | 0.0171 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.004 | 0.0156 | 0.1989 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0018 | 0.0017 | 0.0021 |
Echinococcus granulosus | proto oncogene serine:threonine protein kinase | 0.1089 | 0.6587 | 1 |
Onchocerca volvulus | 0.0082 | 0.041 | 0.0583 | |
Trypanosoma brucei | unspecified product | 0.0034 | 0.0116 | 0.1481 |
Trypanosoma cruzi | phosphatidylinositol 3-related kinase, putative | 0.0018 | 0.0017 | 0.0547 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0.041 | 0.0618 |
Schistosoma mansoni | rab6-interacting | 0.0019 | 0.0027 | 0.0041 |
Mycobacterium tuberculosis | Probable fructose-bisphosphate aldolase Fba | 0.014 | 0.0769 | 0.1257 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0116 | 0.062 | 0.0937 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0075 | 0.037 | 0.0558 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0027 | 0.0037 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0058 | 0.0267 | 0.0401 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0075 | 0.037 | 0.0562 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0003 | 0.0004 |
Mycobacterium tuberculosis | Probable penicillin-binding protein PbpA | 0.0973 | 0.5876 | 1 |
Echinococcus granulosus | FKBP12 rapamycin complex associated protein | 0.0018 | 0.0017 | 0.0021 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0056 | 0.0254 | 0.0382 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0056 | 0.0254 | 0.024 |
Loa Loa (eye worm) | glutaminase | 0.0269 | 0.1557 | 0.2361 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0065 | 0.0306 | 0.391 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0075 | 0.037 | 0.0558 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0408 | 0.2414 | 0.3662 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.004 | 0.0156 | 0.5086 |
Schistosoma mansoni | rab6-interacting | 0.0019 | 0.0027 | 0.0041 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0287 | 0.1671 | 0.3616 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0333 | 0.0502 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0287 | 0.1671 | 0.3616 |
Schistosoma mansoni | bromodomain containing protein | 0.0062 | 0.0288 | 0.0438 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0082 | 0.041 | 0.0618 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0019 | 0.0027 | 0.0037 |
Leishmania major | target of rapamycin (TOR) kinase 1, putative | 0.0018 | 0.0017 | 0.0547 |
Trypanosoma brucei | phosphatidylinositol 3-related kinase, putative | 0.0018 | 0.0017 | 0.0214 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor1 | 0.0018 | 0.0017 | 0.0547 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0156 | 0.1989 |
Mycobacterium tuberculosis | Probable bifunctional penicillin-binding protein 1A/1B PonA1 (murein polymerase) (PBP1): penicillin-insensitive transglycosylase | 0.0238 | 0.1366 | 0.2278 |
Trichomonas vaginalis | fructose-bisphosphate aldolase, putative | 0.0287 | 0.1671 | 0.3616 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0019 | 0.0027 | 0.0037 |
Mycobacterium leprae | Probable penicillin-binding protein PbpA | 0.0973 | 0.5876 | 1 |
Echinococcus granulosus | zinc finger protein | 0.0019 | 0.0026 | 0.0035 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.004 | 0.0156 | 0.0304 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.004 | 0.0156 | 0.1989 |
Loa Loa (eye worm) | CAMK/PIM protein kinase | 0.1089 | 0.6587 | 1 |
Echinococcus granulosus | muscleblind protein | 0.0146 | 0.0806 | 0.1219 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0022 | 0.0044 | 0.0066 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase domain-containing protein | 0.0023 | 0.0049 | 0.1291 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0287 | 0.1671 | 1 |
Leishmania major | DNA polymerase kappa, putative | 0.0021 | 0.0035 | 0.1148 |
Trypanosoma cruzi | target of rapamycin kinase 3 | 0.0018 | 0.0017 | 0.0547 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.037 | 0.0558 |
Onchocerca volvulus | 0.0059 | 0.0268 | 0.0367 | |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0053 | 0.0231 | 0.0346 |
Mycobacterium tuberculosis | holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie | 0.0023 | 0.0049 | 0.0024 |
Mycobacterium ulcerans | penicillin-binding lipoprotein | 0.0301 | 0.1757 | 0.1996 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0082 | 0.041 | 0.0618 |
Trypanosoma cruzi | Phosphatidylinositol 3-kinase tor2 | 0.0018 | 0.0017 | 0.0547 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0031 | 0.0096 | 0.122 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0056 | 0.0254 | 0.024 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0023 | 0.0049 | 0.0627 |
Brugia malayi | Bromodomain containing protein | 0.0073 | 0.0359 | 0.0541 |
Chlamydia trachomatis | transglycolase/transpeptidase | 0.0746 | 0.4483 | 0.4456 |
Plasmodium falciparum | holo-[acyl-carrier-protein] synthase, putative | 0.0023 | 0.0049 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ID50 (functional) | > 5 uM | Compound was evaluated in vitro for growth-inhibition assay utilizing CCRF-CEM cells, a lymphoblastic leukemic line of human origin | ChEMBL. | 3806575 |
ID50 (functional) | > 5 uM | Compound was evaluated in vitro for growth-inhibition assay utilizing CCRF-CEM cells, a lymphoblastic leukemic line of human origin | ChEMBL. | 3806575 |
Ratio (binding) | 0 | Compound was tested in vitro for ability to bind with double helical calf thymus DNA was determined spectrophotometrically at 480 nmby spectral shift method and the value expressed as the ratio A/Ao; ND means not determined | ChEMBL. | 3806575 |
T1/2 (ADMET) | = 22 min | Time for esterases in unfractionated mouse serum to reduce the concentration of the compound due to thio ester deacylation | ChEMBL. | 3806575 |
T1/2 (ADMET) | = 22 min | Time for esterases in unfractionated mouse serum to reduce the concentration of the compound due to thio ester deacylation | ChEMBL. | 3806575 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.