Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0125 | 0.0088 | 0.0086 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0086 | 0.005 | 0.005 |
Brugia malayi | follicle stimulating hormone receptor | 0.0125 | 0.0088 | 0.0227 |
Brugia malayi | hypothetical protein | 0.0125 | 0.0088 | 0.0227 |
Toxoplasma gondii | alpha/beta hydrolase fold domain-containing protein | 0.0174 | 0.0136 | 1 |
Schistosoma mansoni | biogenic amine receptor | 0.0125 | 0.0088 | 0.0088 |
Echinococcus granulosus | g-protein coupled receptor | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0086 | 0.005 | 0.005 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0125 | 0.0088 | 0.0088 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0125 | 0.0088 | 0.0088 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0125 | 0.0088 | 0.0227 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0125 | 0.0088 | 0.0227 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0125 | 0.0088 | 0.0088 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0072 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0125 | 0.0088 | 0.0086 |
Echinococcus granulosus | acetylcholinesterase | 0.0073 | 0.0037 | 0.0037 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0125 | 0.0088 | 0.0088 |
Onchocerca volvulus | Huntingtin homolog | 0.011 | 0.0073 | 0.2586 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0125 | 0.0088 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0072 | 0.0036 | 0.0036 |
Echinococcus granulosus | expressed conserved protein | 0.0101 | 0.0065 | 0.0065 |
Schistosoma mansoni | amine GPCR | 0.0125 | 0.0088 | 0.0088 |
Brugia malayi | Serotonin receptor | 0.0125 | 0.0088 | 0.0227 |
Echinococcus granulosus | orexin receptor type 2 | 0.0125 | 0.0088 | 0.0088 |
Echinococcus granulosus | allatostatin A receptor | 0.0125 | 0.0088 | 0.0088 |
Onchocerca volvulus | 0.0125 | 0.0088 | 0.3601 | |
Echinococcus granulosus | voltage gated sodium channel Nav1 alpha subunit | 0.0037 | 0.0002 | 0.0002 |
Mycobacterium tuberculosis | Probable lipase/esterase LipN | 0.0174 | 0.0136 | 0.2638 |
Echinococcus granulosus | g protein coupled receptor | 0.0125 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | calcium channel | 0.0086 | 0.005 | 0.0048 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0125 | 0.0088 | 0.0088 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0125 | 0.0088 | 0.0088 |
Treponema pallidum | N-acetylphosphinothricin-tripetide-deacetylase | 0.0174 | 0.0136 | 0.5 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0125 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | acetylcholinesterase | 0.0073 | 0.0037 | 0.0037 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0125 | 0.0088 | 0.0088 |
Schistosoma mansoni | neuropeptide receptor | 0.0125 | 0.0088 | 0.0088 |
Brugia malayi | hypothetical protein | 0.0125 | 0.0088 | 0.0227 |
Mycobacterium ulcerans | esterase LipW | 0.0174 | 0.0136 | 1 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0125 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0193 | 0.0154 | 0.0153 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.0108 | 0.0071 | 0.0184 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0125 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0125 | 0.0088 | 0.0086 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0125 | 0.0088 | 0.0227 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Mycobacterium ulcerans | lipase LipH | 0.0174 | 0.0136 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0125 | 0.0088 | 0.0088 |
Entamoeba histolytica | Acid sphingomyelinase-like phosphodiesterase, putative | 0.0073 | 0.0037 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0125 | 0.0088 | 0.0088 |
Mycobacterium ulcerans | esterase LipC | 0.0174 | 0.0136 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.0125 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0071 | 0.0069 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0125 | 0.0088 | 0.0088 |
Trypanosoma brucei | Isoprenylcysteine alpha-carbonyl methylesterase, putative | 0.0174 | 0.0136 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0073 | 0.0037 | 0.0037 |
Schistosoma mansoni | biogenic amine receptor | 0.0125 | 0.0088 | 0.0088 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0125 | 0.0088 | 0.0088 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0125 | 0.0088 | 0.0088 |
Brugia malayi | Carboxylesterase family protein | 0.0073 | 0.0037 | 0.0096 |
Mycobacterium ulcerans | carboxylesterase LipQ | 0.0174 | 0.0136 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0072 | 0.0036 | 0.1908 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Entamoeba histolytica | Acid sphingomyelinase-like phosphodiesterase, putative | 0.0073 | 0.0037 | 1 |
Brugia malayi | Dopamine receptor protein 2 | 0.0125 | 0.0088 | 0.0227 |
Schistosoma mansoni | neuropeptide receptor | 0.0125 | 0.0088 | 0.0088 |
Schistosoma mansoni | histamine h1 receptor | 0.0125 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0073 | 0.0071 |
Mycobacterium tuberculosis | Probable carboxylesterase LipQ | 0.0174 | 0.0136 | 0.2638 |
Trypanosoma cruzi | Alpha/beta hydrolase domain-containing protein | 0.0174 | 0.0136 | 1 |
Echinococcus multilocularis | hormone sensitive lipase | 1.0272 | 1 | 1 |
Onchocerca volvulus | 0.0125 | 0.0088 | 0.3601 | |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0072 | 0.0036 | 0.2545 |
Echinococcus granulosus | serotonin receptor | 0.0125 | 0.0088 | 0.0088 |
Onchocerca volvulus | 0.0125 | 0.0088 | 0.3601 | |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0125 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | ammd protein | 0.0174 | 0.0136 | 0.0134 |
Brugia malayi | hypothetical protein | 0.0125 | 0.0088 | 0.0227 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0037 | 0.0002 | 0.0002 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0125 | 0.0088 | 0.0088 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0125 | 0.0088 | 0.0088 |
Trichomonas vaginalis | Esterase, putative | 0.0174 | 0.0136 | 0.7496 |
Mycobacterium tuberculosis | Probable esterase LipO | 0.0174 | 0.0136 | 0.2638 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Schistosoma mansoni | hormone-sensitive lipase (S09 family) | 1.0272 | 1 | 1 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0125 | 0.0088 | 0.0088 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0125 | 0.0088 | 0.0088 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0167 | 0.0129 | 0.0129 |
Brugia malayi | neuropeptide F receptor | 0.0125 | 0.0088 | 0.0227 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | neutral sphingomyelinase | 0.0108 | 0.0071 | 0.0071 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Onchocerca volvulus | 0.0125 | 0.0088 | 0.3601 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0125 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | g protein coupled receptor | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | serotonin receptor | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | geminin | 0.0163 | 0.0125 | 0.0125 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Trypanosoma cruzi | Voltage-dependent calcium channel subunit, putative | 0.0052 | 0.0017 | 0.1131 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0125 | 0.0088 | 0.0088 |
Mycobacterium tuberculosis | Possible lipase LipU | 0.0174 | 0.0136 | 0.2638 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0174 | 0.0136 | 0.0136 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0167 | 0.0129 | 0.0129 |
Schistosoma mansoni | voltage-gated cation channel | 0.0086 | 0.005 | 0.005 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0037 | 0.0002 | 0.0005 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0125 | 0.0088 | 0.0088 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0125 | 0.0088 | 0.0088 |
Onchocerca volvulus | 0.0125 | 0.0088 | 0.3601 | |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0125 | 0.0088 | 0.3601 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0125 | 0.0088 | 0.0088 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 | 0.0086 | 0.005 | 0.005 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0125 | 0.0088 | 0.0088 |
Mycobacterium ulcerans | lipase LipU | 0.0174 | 0.0136 | 1 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0125 | 0.0088 | 0.0088 |
Brugia malayi | beta-lactamase family protein | 0.0072 | 0.0036 | 0.0093 |
Trichomonas vaginalis | set domain proteins, putative | 0.022 | 0.018 | 1 |
Trichomonas vaginalis | Esterase, putative | 0.0174 | 0.0136 | 0.7496 |
Onchocerca volvulus | 0.0125 | 0.0088 | 0.3601 | |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0125 | 0.0088 | 0.0088 |
Schistosoma mansoni | hormone-sensitive lipase (S09 family) | 1.0272 | 1 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0125 | 0.0088 | 0.0088 |
Trypanosoma cruzi | Isoprenylcysteine alpha-carbonyl methylesterase, putative | 0.0174 | 0.0136 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0125 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Onchocerca volvulus | 0.0096 | 0.006 | 0.1657 | |
Leishmania major | ecotin, putative | 0.0174 | 0.0136 | 1 |
Onchocerca volvulus | 0.0125 | 0.0088 | 0.3601 | |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0125 | 0.0088 | 0.0088 |
Schistosoma mansoni | hormone-sensitive lipase (S09 family) | 1.0272 | 1 | 1 |
Brugia malayi | Melatonin receptor type 1A | 0.0125 | 0.0088 | 0.0227 |
Onchocerca volvulus | Putative neutral sphingomyelinase | 0.0108 | 0.0071 | 0.2446 |
Schistosoma mansoni | amine GPCR | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0125 | 0.0088 | 0.0088 |
Brugia malayi | AKH receptor | 0.0125 | 0.0088 | 0.0227 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0072 | 0.0036 | 0.2545 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0073 | 0.0037 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0037 | 0.0035 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0002 | 0.0524 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0037 | 0.0002 | 0.0524 |
Mycobacterium tuberculosis | Probable esterase LipC | 0.0174 | 0.0136 | 0.2638 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0072 | 0.0036 | 0.0036 |
Schistosoma mansoni | neuropeptide receptor | 0.0125 | 0.0088 | 0.0088 |
Onchocerca volvulus | 0.0125 | 0.0088 | 0.3601 | |
Schistosoma mansoni | high voltage-activated calcium channel Cav2A | 0.0086 | 0.005 | 0.005 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0167 | 0.0129 | 0.0127 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0036 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0125 | 0.0088 | 0.0088 |
Brugia malayi | beta-lactamase family protein | 0.0072 | 0.0036 | 0.0093 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0125 | 0.0088 | 0.0227 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Mycobacterium tuberculosis | Possible esterase LipW | 0.0174 | 0.0136 | 0.2638 |
Echinococcus multilocularis | acetylcholinesterase | 0.0073 | 0.0037 | 0.0037 |
Onchocerca volvulus | Huntingtin homolog | 0.011 | 0.0073 | 0.2586 |
Schistosoma mansoni | neuropeptide receptor | 0.0125 | 0.0088 | 0.0088 |
Brugia malayi | larval opioid receptor | 0.0125 | 0.0088 | 0.0227 |
Brugia malayi | Dopamine receptor | 0.0125 | 0.0088 | 0.0227 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Echinococcus granulosus | g protein coupled receptor | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | voltage dependent L type calcium channel subunit | 0.0086 | 0.005 | 0.005 |
Brugia malayi | Serotonin receptor | 0.0125 | 0.0088 | 0.0227 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Mycobacterium ulcerans | lipase LipU | 0.0174 | 0.0136 | 1 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0125 | 0.0088 | 0.0227 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9D | 0.0174 | 0.0136 | 1 |
Onchocerca volvulus | 0.0125 | 0.0088 | 0.3601 | |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0072 | 0.0036 | 0.1908 |
Mycobacterium tuberculosis | Probable lipase LipH | 0.0174 | 0.0136 | 0.2638 |
Schistosoma mansoni | opsin-like receptor | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0125 | 0.0088 | 0.0088 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | fmrfamide receptor | 0.0125 | 0.0088 | 0.0088 |
Onchocerca volvulus | 0.0125 | 0.0088 | 0.3601 | |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0125 | 0.0088 | 0.0088 |
Brugia malayi | G protein-coupled receptor | 0.0125 | 0.0088 | 0.0227 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0125 | 0.0088 | 0.0088 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0125 | 0.0088 | 0.0088 |
Schistosoma mansoni | hypothetical protein | 0.0163 | 0.0125 | 0.0125 |
Loa Loa (eye worm) | hypothetical protein | 1.0272 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0073 | 0.0071 |
Onchocerca volvulus | 0.0125 | 0.0088 | 0.3601 | |
Schistosoma mansoni | amine GPCR | 0.0125 | 0.0088 | 0.0088 |
Schistosoma mansoni | alpha-glucosidase | 0.0143 | 0.0106 | 0.0106 |
Brugia malayi | Carboxylesterase family protein | 0.0073 | 0.0037 | 0.0096 |
Brugia malayi | ORL1-like opioid receptor | 0.0125 | 0.0088 | 0.0227 |
Loa Loa (eye worm) | beta-lactamase | 0.0072 | 0.0036 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | fmrfamide receptor | 0.0125 | 0.0088 | 0.0088 |
Mycobacterium ulcerans | hypothetical protein | 0.0174 | 0.0136 | 1 |
Mycobacterium ulcerans | acetyl hydrolase MbtJ | 0.0174 | 0.0136 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0125 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0036 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Echinococcus granulosus | neutral sphingomyelinase | 0.0108 | 0.0071 | 0.0071 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0125 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.005 | 0.0048 |
Brugia malayi | G-protein coupled receptor | 0.0125 | 0.0088 | 0.0227 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0125 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0125 | 0.0088 | 0.0086 |
Onchocerca volvulus | 0.0125 | 0.0088 | 0.3601 | |
Onchocerca volvulus | 0.0125 | 0.0088 | 0.3601 | |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Echinococcus multilocularis | allatostatin A receptor | 0.0125 | 0.0088 | 0.0088 |
Schistosoma mansoni | alpha-glucosidase | 0.0143 | 0.0106 | 0.0106 |
Brugia malayi | hypothetical protein | 0.0125 | 0.0088 | 0.0227 |
Brugia malayi | putative neuropeptide receptor | 0.0125 | 0.0088 | 0.0227 |
Brugia malayi | hypothetical protein | 0.0125 | 0.0088 | 0.0227 |
Echinococcus multilocularis | voltage dependent calcium channel | 0.0086 | 0.005 | 0.005 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0072 | 0.0036 | 0.2545 |
Schistosoma mansoni | hypothetical protein | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0125 | 0.0088 | 0.0088 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0125 | 0.0088 | 0.0088 |
Mycobacterium tuberculosis | Probable acetyl-hydrolase/esterase LipR | 0.0174 | 0.0136 | 0.2638 |
Echinococcus granulosus | acetylcholinesterase | 0.0073 | 0.0037 | 0.0037 |
Brugia malayi | beta-lactamase | 0.0072 | 0.0036 | 0.0093 |
Mycobacterium ulcerans | lipase LipI | 0.0174 | 0.0136 | 1 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0125 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Echinococcus granulosus | neuropeptide receptor | 0.0125 | 0.0088 | 0.0088 |
Echinococcus granulosus | neuropeptide receptor | 0.0125 | 0.0088 | 0.0088 |
Schistosoma mansoni | adenoreceptor | 0.0125 | 0.0088 | 0.0088 |
Mycobacterium leprae | Possible lipase LipU | 0.0174 | 0.0136 | 1 |
Schistosoma mansoni | amine GPCR | 0.0125 | 0.0088 | 0.0088 |
Onchocerca volvulus | 0.0174 | 0.0136 | 0.6906 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | somatostatin receptor | 0.0125 | 0.0088 | 0.0088 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0459 | 0.0414 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0125 | 0.0088 | 0.0088 |
Schistosoma mansoni | amine GPCR | 0.0125 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Schistosoma mansoni | alpha glucosidase | 0.0037 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0125 | 0.0088 | 0.0086 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0125 | 0.0088 | 0.0086 |
Echinococcus multilocularis | serotonin receptor | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0125 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0036 | 0.0034 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0125 | 0.0088 | 0.0227 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0072 | 0.0036 | 0.1908 |
Trichomonas vaginalis | Esterase, putative | 0.0174 | 0.0136 | 0.7496 |
Echinococcus granulosus | geminin | 0.0163 | 0.0125 | 0.0125 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Trichomonas vaginalis | esterase, putative | 0.0072 | 0.0036 | 0.1908 |
Onchocerca volvulus | 0.022 | 0.018 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.4011 | 0.3884 | 0.3883 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0125 | 0.0088 | 0.0088 |
Echinococcus granulosus | voltage dependent calcium channel | 0.0086 | 0.005 | 0.005 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0125 | 0.0088 | 0.0088 |
Brugia malayi | RE15519p | 0.0125 | 0.0088 | 0.0227 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0167 | 0.0129 | 0.0331 |
Echinococcus granulosus | voltage dependent L type calcium channel subunit|voltage dependent calcium channel | 0.0086 | 0.005 | 0.005 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0036 | 0.0034 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0072 | 0.0036 | 0.1908 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0072 | 0.0036 | 0.1908 |
Schistosoma mansoni | opsin-like receptor | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0125 | 0.0088 | 0.0088 |
Onchocerca volvulus | 0.0125 | 0.0088 | 0.3601 | |
Echinococcus multilocularis | conserved hypothetical protein | 0.0101 | 0.0065 | 0.0065 |
Schistosoma mansoni | hypothetical protein | 0.0125 | 0.0088 | 0.0088 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0125 | 0.0088 | 0.0088 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0125 | 0.0088 | 0.0088 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0072 | 0.0036 | 0.0036 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0036 | 0.0034 |
Echinococcus granulosus | somatostatin receptor | 0.0125 | 0.0088 | 0.0088 |
Brugia malayi | hypothetical protein | 0.011 | 0.0073 | 0.0189 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0125 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0125 | 0.0088 | 0.0086 |
Leishmania major | hypothetical protein, conserved | 0.0072 | 0.0036 | 0.2545 |
Brugia malayi | neuropeptide F receptor | 0.0125 | 0.0088 | 0.0227 |
Mycobacterium ulcerans | lipase/esterase LipN | 0.0174 | 0.0136 | 1 |
Echinococcus multilocularis | sodium channel protein | 0.0037 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0125 | 0.0088 | 0.0086 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0125 | 0.0088 | 0.0088 |
Mycobacterium tuberculosis | Probable non lipolytic carboxylesterase NlhH | 0.0174 | 0.0136 | 0.2638 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Mycobacterium tuberculosis | Probable esterase/lipase LipF | 0.0174 | 0.0136 | 0.2638 |
Onchocerca volvulus | 0.0125 | 0.0088 | 0.3601 | |
Toxoplasma gondii | alpha/beta hydrolase fold domain-containing protein | 0.0174 | 0.0136 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0125 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | aryl-acylamidase | 0.0174 | 0.0136 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Toxoplasma gondii | ABC1 family protein | 0.0072 | 0.0036 | 0.2545 |
Echinococcus multilocularis | g protein coupled receptor | 0.0125 | 0.0088 | 0.0088 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0072 | 0.0036 | 0.0093 |
Brugia malayi | hypothetical protein | 0.0125 | 0.0088 | 0.0227 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0125 | 0.0088 | 0.0088 |
Brugia malayi | hypothetical protein | 0.0125 | 0.0088 | 0.0227 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0125 | 0.0088 | 0.0227 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Brugia malayi | sulfakinin receptor protein | 0.4011 | 0.3884 | 1 |
Brugia malayi | hypothetical protein | 0.0125 | 0.0088 | 0.0227 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0125 | 0.0088 | 0.0088 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0125 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Echinococcus multilocularis | sex peptide receptor | 0.0125 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Schistosoma mansoni | hypothetical protein | 0.0125 | 0.0088 | 0.0088 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0167 | 0.0129 | 0.0129 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0125 | 0.0088 | 0.0088 |
Echinococcus granulosus | hypothetical protein | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0125 | 0.0088 | 0.0088 |
Schistosoma mansoni | myosin xvIII | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0125 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0037 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0037 | 0.0035 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0125 | 0.0088 | 0.0088 |
Brugia malayi | hypothetical protein | 0.0125 | 0.0088 | 0.0227 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0125 | 0.0088 | 0.0088 |
Brugia malayi | G-protein coupled receptor | 0.0125 | 0.0088 | 0.0227 |
Onchocerca volvulus | 0.0125 | 0.0088 | 0.3601 | |
Echinococcus multilocularis | expressed conserved protein | 0.0101 | 0.0065 | 0.0065 |
Mycobacterium ulcerans | esterase LipO | 0.0174 | 0.0136 | 1 |
Mycobacterium tuberculosis | Putative acetyl hydrolase MbtJ | 0.0174 | 0.0136 | 0.2638 |
Onchocerca volvulus | 0.0125 | 0.0088 | 0.3601 | |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Echinococcus multilocularis | neuropeptide receptor | 0.0125 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0125 | 0.0088 | 0.0088 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0125 | 0.0088 | 0.0088 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0125 | 0.0088 | 0.0088 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0086 | 0.005 | 0.005 |
Mycobacterium ulcerans | esterase/lipase | 0.0174 | 0.0136 | 1 |
Echinococcus granulosus | hypothetical protein | 0.0101 | 0.0065 | 0.0065 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Brugia malayi | Dopamine receptor protein 1 | 0.0125 | 0.0088 | 0.0227 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0072 | 0.0036 | 0.0034 |
Mycobacterium ulcerans | membrane-bound esterase LipM | 0.0174 | 0.0136 | 1 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0125 | 0.0088 | 0.0088 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0125 | 0.0088 | 0.0088 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0125 | 0.0088 | 0.0227 |
Echinococcus multilocularis | neuropeptide receptor | 0.0125 | 0.0088 | 0.0088 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0125 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Brugia malayi | GnHR receptor homolog | 0.0125 | 0.0088 | 0.0227 |
Schistosoma mansoni | hypothetical protein | 0.0163 | 0.0125 | 0.0125 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0125 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0174 | 0.0136 | 0.7496 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0125 | 0.0088 | 0.3601 |
Schistosoma mansoni | hypothetical protein | 0.0125 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0125 | 0.0088 | 0.0086 |
Leishmania major | hypothetical protein, conserved | 0.0174 | 0.0136 | 1 |
Echinococcus granulosus | neuropeptide s receptor | 0.0125 | 0.0088 | 0.0088 |
Trypanosoma brucei | Voltage-dependent calcium channel subunit, putative | 0.0052 | 0.0017 | 0.1131 |
Echinococcus granulosus | sex peptide receptor | 0.0125 | 0.0088 | 0.0088 |
Echinococcus granulosus | carboxylesterase 5A | 0.0073 | 0.0037 | 0.0037 |
Schistosoma mansoni | high voltage-activated calcium channel Cav1 | 0.0086 | 0.005 | 0.005 |
Brugia malayi | Pre-SET motif family protein | 0.0193 | 0.0154 | 0.0398 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Brugia malayi | Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog | 0.0086 | 0.005 | 0.0129 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0037 | 0.0002 | 0.0002 |
Echinococcus multilocularis | g protein coupled receptor | 0.0125 | 0.0088 | 0.0088 |
Schistosoma mansoni | neutral sphingomyelinase | 0.0108 | 0.0071 | 0.0071 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0125 | 0.0088 | 0.0088 |
Brugia malayi | hypothetical protein | 0.4011 | 0.3884 | 1 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0125 | 0.0088 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0036 | 0.0034 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0125 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Brugia malayi | aryl-acylamidase | 0.0174 | 0.0136 | 0.035 |
Schistosoma mansoni | biogenic amine receptor | 0.0125 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.0088 | 0.0086 |
Mycobacterium tuberculosis | Probable esterase LipM | 0.0174 | 0.0136 | 0.2638 |
Echinococcus granulosus | fmrfamide receptor | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0125 | 0.0088 | 0.0088 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0125 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | carboxylesterase | 0.0073 | 0.0037 | 0.0035 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0125 | 0.0088 | 0.0088 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0073 | 0.0037 | 0.0035 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu | 0.0086 | 0.005 | 0.005 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0125 | 0.0088 | 0.0088 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0125 | 0.0088 | 0.0088 |
Trypanosoma cruzi | Isoprenylcysteine alpha-carbonyl methylesterase, putative | 0.0174 | 0.0136 | 1 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0125 | 0.0088 | 0.0088 |
Echinococcus multilocularis | voltage dependent calcium channel type d subunit | 0.0086 | 0.005 | 0.005 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0125 | 0.0088 | 0.0088 |
Plasmodium vivax | hypothetical protein, conserved | 0.0072 | 0.0036 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 1 | Compound was assessed for its ability to produce catalepsy in rats; Dose administered perorally is 10 mg/kg; Group score is 4-7 | ChEMBL. | 6105216 |
Activity (functional) | = 2 | Compound was assessed for its ability to block a conditioned avoidance response; Dose administered perorally is 10 mg/kg; 31-50%block | ChEMBL. | 6105216 |
EDmin (functional) | = 50 mg kg-1 | Hypothermia in mice after peroral administration | ChEMBL. | 6105216 |
EDmin (functional) | = 50 mg kg-1 | Hypothermia in mice after peroral administration | ChEMBL. | 6105216 |
LD50 (ADMET) | = 200 mg kg-1 | Lethal dose in mice after perorla administration | ChEMBL. | 6105216 |
LD50 (ADMET) | = 200 mg kg-1 | Lethal dose in mice after perorla administration | ChEMBL. | 6105216 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.