TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 401.504 | Formula: C24H27N5O
H donors: 4 H acceptors: 2 LogP: 3.8 Rotable bonds: 8
Rule of 5 violations (Lipinski): 1
SMILES: O=C(NC(C)(C)C)N[C@@H](c1[nH]cc(n1)c1ccccc1)Cc1c[nH]c2c1cccc2
InChi: 1S/C24H27N5O/c1-24(2,3)29-23(30)28-20(13-17-14-25-19-12-8-7-11-18(17)19)22-26-15-21(27-22)16-9-5-4-6-10-16/h4-12,14-15,20,25H,13H2,1-3H3,(H,26,27)(H2,28,29,30)/t20-/m1/s1
InChiKey: VFJFHKSDNUMTES-HXUWFJFHSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	somatostatin receptor 1	Starlite/ChEMBL	References
Homo sapiens	somatostatin receptor 5	Starlite/ChEMBL	References
Homo sapiens	somatostatin receptor 4	Starlite/ChEMBL	References
Homo sapiens	somatostatin receptor 3	Starlite/ChEMBL	References
Homo sapiens	somatostatin receptor 2	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	somatostatin receptor 2	369 aa	411 aa	18.7 %
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	somatostatin receptor 4	388 aa	372 aa	20.7 %
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	somatostatin receptor 5	364 aa	392 aa	19.4 %
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	somatostatin receptor 1	391 aa	368 aa	21.5 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Brugia malayi	orphan nuclear receptor NR2E1	0.019	0.2318	0.4588
Schistosoma mansoni	nuclear hormone receptor superfamily protein-related	0.019	0.2318	0.253
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0404	0.5051	1
Echinococcus multilocularis	nuclear receptor nhr 48	0.019	0.2318	0.2316
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0017	0.009	0.0089
Brugia malayi	hypothetical protein	0.0017	0.009	0.0179
Echinococcus multilocularis	muscleblind protein	0.0145	0.1742	0.174
Schistosoma mansoni	hypothetical protein	0.0017	0.009	0.0019
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.019	0.2318	0.2316
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0213	0.261	0.2861
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.003	0.0257	0.0207
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Schistosoma mansoni	hypothetical protein	0.0017	0.009	0.0019
Echinococcus granulosus	rhodopsin orphan GPCR	0.0017	0.009	0.01
Brugia malayi	hypothetical protein	0.0017	0.009	0.0179
Echinococcus multilocularis	dnaJ subfamily B	0.0398	0.4983	0.4982
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Trichomonas vaginalis	set domain proteins, putative	0.0231	0.2842	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0017	0.009	0.0089
Echinococcus granulosus	nuclear receptor subfamily 4 group A	0.019	0.2318	0.2591
Loa Loa (eye worm)	nuclear hormone receptor-like 1	0.0213	0.261	0.4573
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0017	0.009	0.0179
Echinococcus multilocularis	dro:myosuppressin receptor	0.0017	0.009	0.0089
Echinococcus granulosus	rhodopsin orphan GPCR	0.0017	0.009	0.01
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.003	0.0257	0.0256
Loa Loa (eye worm)	hypothetical protein	0.019	0.2318	0.406
Mycobacterium tuberculosis	Probable glutamine synthetase GlnA2 (glutamine synthase) (GS-II)	0.0455	0.5707	1
Echinococcus granulosus	FTZ F1 alpha	0.0404	0.5051	0.5648
Brugia malayi	Nuclear hormone receptor family member nhr-1	0.0404	0.5051	1
Echinococcus multilocularis	isocitrate dehydrogenase 2 (NADP+)	0.0015	0.0074	0.0073
Schistosoma mansoni	opsin-like receptor	0.0017	0.009	0.0019
Schistosoma mansoni	nuclear hormone receptor	0.019	0.2318	0.253
Echinococcus multilocularis	fmrfamide receptor	0.0017	0.009	0.0089
Echinococcus granulosus	transcription factor btf3	0.0034	0.0313	0.0349
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-41	0.0404	0.5051	0.8851
Echinococcus multilocularis	thyroid hormone receptor alpha	0.0404	0.5051	0.505
Echinococcus multilocularis	GPCR, family 2	0.0015	0.0074	0.0072
Echinococcus granulosus	G protein coupled receptor 139	0.0017	0.009	0.01
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0404	0.5051	1
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Echinococcus granulosus	nuclear receptor subfamily 1 group D	0.0213	0.261	0.2918
Brugia malayi	Serotonin receptor	0.0017	0.009	0.0179
Brugia malayi	RE15519p	0.0017	0.009	0.0179
Schistosoma mansoni	photoreceptor-specific nuclear receptor related	0.0404	0.5051	0.5613
Echinococcus granulosus	histone lysine methyltransferase setb	0.003	0.0257	0.0286
Schistosoma mansoni	retinoid-x-receptor (RXR)	0.0404	0.5051	0.5613
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.003	0.0257	0.0207
Echinococcus multilocularis	allatostatin A receptor	0.0017	0.009	0.0089
Trypanosoma cruzi	transcription factor btf3, putative	0.0034	0.0313	0.027
Echinococcus multilocularis	sex peptide receptor	0.0017	0.009	0.0089
Loa Loa (eye worm)	hypothetical protein	0.0404	0.5051	0.8851
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Loa Loa (eye worm)	nuclear hormone receptor	0.019	0.2318	0.406
Brugia malayi	nuclear receptor subfamily 1, group D, member 1, putative	0.019	0.2318	0.4588
Schistosoma mansoni	nuclear receptor	0.019	0.2318	0.253
Echinococcus multilocularis	g protein coupled receptor	0.0017	0.009	0.0089
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0017	0.009	0.0019
Echinococcus multilocularis	hepatocyte nuclear factor 4 alpha	0.0404	0.5051	0.505
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0017	0.009	0.0019
Brugia malayi	nuclear hormone receptor family member odr-7	0.019	0.2318	0.4588
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0017	0.009	0.0019
Echinococcus granulosus	geminin	0.0165	0.1992	0.2227
Echinococcus granulosus	NADP dependent isocitrate dehydrogenase	0.0015	0.0074	0.0081
Brugia malayi	nuclear receptor RXR	0.0213	0.261	0.5168
Brugia malayi	Nuclear hormone receptor family member nhr-41	0.0404	0.5051	1
Schistosoma mansoni	hypothetical protein	0.0017	0.009	0.0019
Brugia malayi	putative neuropeptide receptor NPR1	0.0017	0.009	0.0179
Onchocerca volvulus		0.0404	0.5051	0.8833
Echinococcus granulosus	FTZ F1 nuclear receptor protein	0.0404	0.5051	0.5648
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Brugia malayi	conserved hypotetical protein	0.019	0.2318	0.4588
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0017	0.009	0.0019
Echinococcus multilocularis	FTZ F1 alpha	0.0404	0.5051	0.505
Onchocerca volvulus	Steroid hormone receptor family member cnr14 homolog	0.0404	0.5051	0.8833
Toxoplasma gondii	histone lysine methyltransferase SET1	0.0054	0.057	0.088
Loa Loa (eye worm)	G-protein coupled receptor	0.0017	0.009	0.0156
Brugia malayi	G protein-coupled receptor F59B2.13	0.0017	0.009	0.0179
Echinococcus granulosus	neuropeptide receptor	0.0017	0.009	0.01
Schistosoma mansoni	coup transcription factor	0.0404	0.5051	0.5613
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0203	0.2483	0.4349
Schistosoma mansoni	cpg binding protein	0.0028	0.0235	0.0182
Brugia malayi	hypothetical protein	0.0017	0.009	0.0179
Echinococcus granulosus	rhodopsin orphan GPCR	0.0017	0.009	0.01
Schistosoma mansoni	thyroid hormone receptor	0.0404	0.5051	0.5613
Echinococcus granulosus	g protein coupled receptor	0.0017	0.009	0.01
Brugia malayi	hypothetical protein	0.0017	0.009	0.0179
Schistosoma mansoni	opsin-like receptor	0.0017	0.009	0.0019
Entamoeba histolytica	glutamine synthetase, putative	0.0178	0.2164	1
Echinococcus granulosus	g-protein coupled receptor	0.0017	0.009	0.01
Onchocerca volvulus	Protein ultraspiracle homolog	0.0404	0.5051	0.8833
Loa Loa (eye worm)	CXXC zinc finger family protein	0.0028	0.0235	0.041
Schistosoma mansoni	hepatocyte nuclear factor 4-alpha (hnf-4-alpha)	0.019	0.2318	0.253
Echinococcus granulosus	orexin receptor type 2	0.0017	0.009	0.01
Echinococcus granulosus	g protein coupled receptor	0.0017	0.009	0.01
Brugia malayi	hypothetical protein	0.0213	0.261	0.5168
Loa Loa (eye worm)	hypothetical protein	0.0213	0.261	0.4573
Brugia malayi	Dopamine receptor	0.0017	0.009	0.0179
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Brugia malayi	G-protein coupled receptor	0.0017	0.009	0.0179
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0049	0.0499	0.0872
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Trichomonas vaginalis	glutamine synthetase-bacteria, putative	0.0178	0.2164	0.7321
Echinococcus multilocularis	serotonin receptor	0.0017	0.009	0.0089
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0017	0.009	0.0089
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Echinococcus granulosus	rhodopsin orphan GPCR	0.0017	0.009	0.01
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0017	0.009	0.01
Trypanosoma cruzi	glutamine synthetase, putative	0.0707	0.8941	1
Loa Loa (eye worm)	hypothetical protein	0.0404	0.5051	0.8851
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0017	0.009	0.0089
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0015	0.0074	0.0146
Schistosoma mansoni	retinoic acid receptor RXR	0.0404	0.5051	0.5613
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0017	0.009	0.0019
Echinococcus multilocularis	cpg binding protein	0.003	0.0256	0.0254
Brugia malayi	Nuclear hormone receptor family member nhr-31	0.0404	0.5051	1
Brugia malayi	isocitrate dehydrogenase	0.0015	0.0074	0.0147
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.0015	0.0074	0.0073
Brugia malayi	hypothetical protein	0.0017	0.009	0.0179
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0017	0.009	0.0179
Loa Loa (eye worm)	TYRA-2 protein	0.0017	0.009	0.0156
Echinococcus multilocularis	histone lysine N methyltransferase SETMAR	0.003	0.0257	0.0256
Echinococcus granulosus	allatostatin A receptor	0.0017	0.009	0.01
Echinococcus granulosus	ecdysone induced protein 78C	0.0404	0.5051	0.5648
Loa Loa (eye worm)	hypothetical protein	0.0015	0.0074	0.0127
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-1	0.0404	0.5051	0.8851
Echinococcus multilocularis	serotonin receptor	0.0017	0.009	0.0089
Plasmodium vivax	basic transcription factor 3b, putative	0.0034	0.0313	0.0425
Plasmodium falciparum	basic transcription factor 3b, putative	0.0034	0.0313	0.0425
Schistosoma mansoni	hypothetical protein	0.0165	0.1992	0.2164
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0404	0.5051	0.5648
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0017	0.009	0.0089
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0017	0.009	0.0179
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Onchocerca volvulus	Nuclear receptor subfamily 6 group A member 1 homolog	0.019	0.2318	0.3965
Loa Loa (eye worm)	hypothetical protein	0.0404	0.5051	0.8851
Brugia malayi	Nuclear hormone receptor family member nhr-40	0.0404	0.5051	1
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0017	0.009	0.0019
Trichomonas vaginalis	glutamine synthetase, putative	0.0178	0.2164	0.7321
Loa Loa (eye worm)	melatonin receptor type 1A	0.0017	0.009	0.0156
Trypanosoma brucei	glutamine synthetase, putative	0.0707	0.8941	1
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0017	0.009	0.0179
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0017	0.009	0.0089
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0017	0.009	0.0089
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0015	0.0074	0.0127
Loa Loa (eye worm)	hypothetical protein	0.0213	0.261	0.4573
Echinococcus granulosus	g protein coupled receptor	0.0017	0.009	0.01
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.006	0.0651	0.0651
Leishmania major	basic transcription factor 3a, putative	0.0034	0.0313	0.027
Loa Loa (eye worm)	hypothetical protein	0.0404	0.5051	0.8851
Loa Loa (eye worm)	hypothetical protein	0.019	0.2318	0.406
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0017	0.009	0.0019
Schistosoma mansoni	hypothetical protein	0.0165	0.1992	0.2164
Echinococcus granulosus	thyroid hormone receptor alpha	0.019	0.2318	0.2591
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Echinococcus granulosus	retinoic acid receptor rxr beta a	0.0404	0.5051	0.5648
Brugia malayi	ORL1-like opioid receptor	0.0017	0.009	0.0179
Brugia malayi	Nuclear hormone receptor-like 1	0.0213	0.261	0.5168
Brugia malayi	neuropeptide F receptor	0.0017	0.009	0.0179
Echinococcus granulosus	GPCR family 2	0.0015	0.0074	0.0081
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0015	0.0074	0.0072
Loa Loa (eye worm)	neuropeptide F receptor	0.0017	0.009	0.0156
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0017	0.009	0.0019
Schistosoma mansoni	steroid hormone receptor ad4bp	0.0404	0.5051	0.5613
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0017	0.009	0.0019
Toxoplasma gondii	glutamine synthetase, type I, putative	0.0455	0.5707	1
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0017	0.009	0.0019
Loa Loa (eye worm)	hypothetical protein	0.0404	0.5051	0.8851
Brugia malayi	Dopamine receptor protein 2	0.0017	0.009	0.0179
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0017	0.009	0.0089
Schistosoma mansoni	amine GPCR	0.0017	0.009	0.0019
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0017	0.009	0.0019
Trypanosoma cruzi	glutamine synthetase, putative	0.0707	0.8941	1
Mycobacterium ulcerans	glutamine synthetase GlnA1	0.0455	0.5707	1
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0404	0.5051	0.505
Brugia malayi	sulfakinin receptor protein	0.0017	0.009	0.0179
Echinococcus granulosus	hypothetical protein	0.0017	0.009	0.01
Echinococcus granulosus	neuropeptide s receptor	0.0465	0.5834	0.6524
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0017	0.009	0.01
Echinococcus multilocularis	g protein coupled receptor	0.0017	0.009	0.0089
Loa Loa (eye worm)	hypothetical protein	0.019	0.2318	0.406
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1742	0.305
Schistosoma mansoni	nuclear receptor 2DBD-gamma	0.0404	0.5051	0.5613
Brugia malayi	G protein-coupled receptor	0.0017	0.009	0.0179
Schistosoma mansoni	neuropeptide receptor	0.0017	0.009	0.0019
Echinococcus granulosus	somatostatin receptor	0.0017	0.009	0.01
Echinococcus granulosus	neuropeptides capa receptor	0.0017	0.009	0.01
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Brugia malayi	larval opioid receptor	0.0017	0.009	0.0179
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Brugia malayi	AKH receptor	0.0017	0.009	0.0179
Echinococcus granulosus	neuropeptides capa receptor	0.0017	0.009	0.01
Echinococcus granulosus	7TM GPCR rhodopsin	0.0017	0.009	0.01
Onchocerca volvulus		0.0028	0.0235	0.0258
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Onchocerca volvulus		0.019	0.2318	0.3965
Echinococcus granulosus	glutamine synthetase	0.0707	0.8941	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0017	0.009	0.0089
Schistosoma mansoni	amine GPCR	0.0017	0.009	0.0019
Echinococcus multilocularis	geminin	0.0165	0.1992	0.1991
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Onchocerca volvulus		0.019	0.2318	0.3965
Schistosoma mansoni	RAR-like nuclear receptor	0.0404	0.5051	0.5613
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0017	0.009	0.0089
Echinococcus granulosus	neuropeptide Y receptor	0.0017	0.009	0.01
Brugia malayi	Nuclear hormone receptor family member nhr-14	0.0404	0.5051	1
Echinococcus granulosus	Nuclear hormone receptor family member nhr 41	0.0404	0.5051	0.5648
Brugia malayi	nuclear receptor NHR-88	0.019	0.2318	0.4588
Loa Loa (eye worm)	hypothetical protein	0.0145	0.1742	0.305
Schistosoma mansoni	neuropeptide F-like receptor	0.0017	0.009	0.0019
Loa Loa (eye worm)	hypothetical protein	0.0404	0.5051	0.8851
Echinococcus granulosus	biogenic amine 5HT receptor	0.0017	0.009	0.01
Schistosoma mansoni	neuropeptide receptor	0.0017	0.009	0.0019
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.003	0.0257	0.0207
Echinococcus multilocularis	COUP TF:Svp nuclear hormone receptor	0.0404	0.5051	0.505
Schistosoma mansoni	amine GPCR	0.0017	0.009	0.0019
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0017	0.009	0.0019
Echinococcus granulosus	cpg binding protein	0.003	0.0256	0.0284
Brugia malayi	Nuclear hormone receptor E75	0.019	0.2318	0.4588
Echinococcus multilocularis	neuropeptides capa receptor	0.0017	0.009	0.0089
Echinococcus multilocularis	muscleblind protein 1	0.0145	0.1742	0.174
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-40	0.0404	0.5051	0.8851
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0017	0.009	0.0089
Brugia malayi	Nuclear hormone receptor-like 1	0.0404	0.5051	1
Schistosoma mansoni	cpg binding protein	0.003	0.0256	0.0205
Schistosoma mansoni	hypothetical protein	0.0033	0.0302	0.0258
Schistosoma mansoni	amine GPCR	0.0017	0.009	0.0019
Brugia malayi	hypothetical protein	0.0017	0.009	0.0179
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0017	0.009	0.0019
Echinococcus granulosus	rhodopsin orphan GPCR	0.0017	0.009	0.01
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0017	0.009	0.0179
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Schistosoma mansoni	histone-lysine n-methyltransferase suv9	0.003	0.0257	0.0207
Echinococcus multilocularis	neuropeptide Y receptor	0.0017	0.009	0.0089
Echinococcus multilocularis	neuropeptide Y receptor	0.0017	0.009	0.0089
Schistosoma mansoni	nuclear hormone receptor	0.0404	0.5051	0.5613
Schistosoma mansoni	amine GPCR	0.0017	0.009	0.0019
Echinococcus granulosus	tm gpcr rhodopsin	0.0017	0.009	0.01
Echinococcus multilocularis	neuropeptide receptor	0.0017	0.009	0.0089
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0017	0.009	0.0156
Brugia malayi	Pre-SET motif family protein	0.003	0.0257	0.0509
Brugia malayi	putative neuropeptide receptor	0.0017	0.009	0.0179
Brugia malayi	Steroid receptor seven-up type 2	0.0404	0.5051	1
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Echinococcus granulosus	tm gpcr rhodopsin	0.0017	0.009	0.01
Schistosoma mansoni	neuropeptide F-like receptor	0.0017	0.009	0.0019
Brugia malayi	hypothetical protein	0.0017	0.009	0.0179
Leishmania major	glutamine synthetase, putative	0.0707	0.8941	1
Brugia malayi	neuropeptide F receptor	0.0017	0.009	0.0179
Schistosoma mansoni	myosin xvIII	0.0017	0.009	0.0019
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0017	0.009	0.0089
Echinococcus multilocularis	g protein coupled receptor	0.0017	0.009	0.0089
Onchocerca volvulus		0.0231	0.2842	0.4899
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0017	0.009	0.01
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0049	0.0499	0.0988
Brugia malayi	latrophilin 2 splice variant baaae	0.0033	0.0302	0.0598
Schistosoma mansoni	glutamine synthetase bacteria	0.0178	0.2164	0.2358
Brugia malayi	Dopamine receptor protein 1	0.0017	0.009	0.0179
Echinococcus multilocularis	neuropeptide receptor A26	0.0465	0.5834	0.5833
Echinococcus granulosus	tm gpcr rhodopsin	0.0017	0.009	0.01
Schistosoma mansoni	neuropeptide receptor	0.0017	0.009	0.0019
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0017	0.009	0.0156
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0017	0.009	0.01
Schistosoma mansoni	hypothetical protein	0.0398	0.4983	0.5536
Onchocerca volvulus	Nuclear receptor subfamily 6 group A member 1 homolog	0.019	0.2318	0.3965
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0015	0.0074	0.0081
Brugia malayi	tailless protein	0.019	0.2318	0.4588
Brugia malayi	Nuclear hormone receptor family member nhr-49	0.0404	0.5051	1
Loa Loa (eye worm)	hypothetical protein	0.019	0.2318	0.406
Echinococcus granulosus	rhodopsin orphan GPCR	0.0017	0.009	0.01
Schistosoma mansoni	neuropeptide f receptor 76f	0.0017	0.009	0.0019
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-49	0.0404	0.5051	0.8851
Echinococcus granulosus	neuropeptide FF receptor 2	0.0017	0.009	0.01
Brugia malayi	hypothetical protein	0.0017	0.009	0.0179
Echinococcus granulosus	neuropeptide Y receptor	0.0017	0.009	0.01
Brugia malayi	CXXC zinc finger family protein	0.0028	0.0235	0.0466
Echinococcus multilocularis	neuropeptide s receptor	0.0465	0.5834	0.5833
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0049	0.0499	0.0988
Schistosoma mansoni	histamine h1 receptor	0.0017	0.009	0.0019
Brugia malayi	nuclear hormone receptor family member nhr-6	0.019	0.2318	0.4588
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0017	0.009	0.0156
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0017	0.009	0.0089
Brugia malayi	glutamine synthetase	0.0252	0.3111	0.616
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0017	0.009	0.0019
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0017	0.009	0.0179
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.0404	0.5051	0.5648
Schistosoma mansoni	biogenic amine receptor	0.0017	0.009	0.0019
Loa Loa (eye worm)	hypothetical protein	0.0049	0.0499	0.0872
Brugia malayi	G-protein coupled receptor	0.0017	0.009	0.0179
Echinococcus granulosus	nuclear receptor 2DBD gamma	0.019	0.2318	0.2591
Brugia malayi	hypothetical protein	0.0017	0.009	0.0179
Echinococcus granulosus	fmrfamide receptor	0.0017	0.009	0.01
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0017	0.009	0.0019
Brugia malayi	Latrophilin receptor protein 2	0.0015	0.0074	0.0146
Brugia malayi	Nuclear hormone receptor family member nhr-19	0.0404	0.5051	1
Echinococcus multilocularis	nuclear receptor subfamily 1 group D	0.0213	0.261	0.2609
Loa Loa (eye worm)	ICD-1 protein	0.0034	0.0313	0.0547
Schistosoma mansoni	transcription factor btf3	0.0034	0.0313	0.027
Trypanosoma brucei	transcription factor BTF3, putative	0.0034	0.0313	0.027
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0017	0.009	0.0089
Brugia malayi	Nuclear hormone receptor family member nhr-3	0.0404	0.5051	1
Echinococcus multilocularis	glutamine synthetase	0.0707	0.8941	0.8941
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0017	0.009	0.01
Echinococcus granulosus	Nuclear hormone receptor HR96	0.019	0.2318	0.2591
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0404	0.5051	1
Loa Loa (eye worm)	nuclear receptor NHR-67	0.019	0.2318	0.406
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0017	0.009	0.0089
Echinococcus granulosus	biogenic amine 5HT receptor	0.0017	0.009	0.01
Brugia malayi	ecdysone receptor	0.019	0.2318	0.4588
Schistosoma mansoni	nuclear hormone receptor	0.019	0.2318	0.253
Loa Loa (eye worm)	DR-78	0.019	0.2318	0.406
Brugia malayi	hypothetical protein	0.019	0.2318	0.4588
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Brugia malayi	beta-NAC-like protein	0.0034	0.0313	0.062
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.0015	0.0074	0.0073
Schistosoma mansoni	glutamine synthetase 1 2 (glutamate-amonia ligase) (gs)	0.0707	0.8941	1
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Schistosoma mansoni	nuclear hormone receptor nor-1/nor-2	0.0404	0.5051	0.5613
Loa Loa (eye worm)	hypothetical protein	0.019	0.2318	0.406
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0017	0.009	0.01
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0017	0.009	0.0089
Schistosoma mansoni	ecdysone-induced protein 78c (dr-78)	0.0213	0.261	0.2861
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-31	0.0404	0.5051	0.8851
Trypanosoma cruzi	transcription factor btf3, putative	0.0034	0.0313	0.027
Mycobacterium tuberculosis	Probable glutamine synthetase GlnA3 (glutamine synthase) (GS-I)	0.0178	0.2164	0.3711
Loa Loa (eye worm)	hypothetical protein	0.003	0.0257	0.0448
Brugia malayi	Nuclear hormone receptor family member nhr-25	0.0404	0.5051	1
Echinococcus granulosus	serotonin receptor	0.0017	0.009	0.01
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0017	0.009	0.0019
Brugia malayi	nuclear receptor RXR	0.019	0.2318	0.4588
Brugia malayi	Melatonin receptor type 1A	0.0017	0.009	0.0179
Loa Loa (eye worm)	hypothetical protein	0.019	0.2318	0.406
Echinococcus multilocularis	somatostatin receptor	0.0017	0.009	0.0089
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Loa Loa (eye worm)	G-protein coupled receptor	0.0017	0.009	0.0156
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0017	0.009	0.0019
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Schistosoma mansoni	thyroid hormone receptor	0.0404	0.5051	0.5613
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0017	0.009	0.0019
Brugia malayi	hypothetical protein	0.019	0.2318	0.4588
Echinococcus granulosus	neuropeptide receptor	0.0017	0.009	0.01
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0017	0.009	0.01
Brugia malayi	Isocitrate dehydrogenase	0.0015	0.0074	0.0147
Loa Loa (eye worm)	isocitrate dehydrogenase	0.0015	0.0074	0.0127
Mycobacterium leprae	PROBABLE GLUTAMINE SYNTHETASE GLNA2 (GLUTAMINE SYNTHASE) (GS-II)	0.0455	0.5707	0.5
Loa Loa (eye worm)	hypothetical protein	0.0213	0.261	0.4573
Echinococcus multilocularis	retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha	0.019	0.2318	0.2316
Loa Loa (eye worm)	nuclear receptor nhr-7B	0.019	0.2318	0.406
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0017	0.009	0.0089
Echinococcus granulosus	neuropeptide receptor A26	0.0465	0.5834	0.6524
Brugia malayi	Ligand-binding domain of nuclear hormone receptor family protein	0.0404	0.5051	1
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Echinococcus multilocularis	isocitrate dehydrogenase	0.0015	0.0074	0.0073
Loa Loa (eye worm)	hypothetical protein	0.019	0.2318	0.406
Schistosoma mansoni	hypothetical protein	0.0017	0.009	0.0019
Loa Loa (eye worm)	hypothetical protein	0.0213	0.261	0.4573
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0017	0.009	0.0019
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0017	0.009	0.0156
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Schistosoma mansoni	biogenic amine receptor	0.0017	0.009	0.0019
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0017	0.009	0.0089
Loa Loa (eye worm)	steroid hormone receptor	0.0404	0.5051	0.8851
Schistosoma mansoni	biogenic amine receptor	0.0017	0.009	0.0019
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0015	0.0074	0.0081
Brugia malayi	Nuclear hormone receptor E75	0.019	0.2318	0.4588
Schistosoma mansoni	adenoreceptor	0.0017	0.009	0.0019
Brugia malayi	nuclear hormone receptor	0.019	0.2318	0.4588
Brugia malayi	Nuclear hormone receptor-like 1	0.0213	0.261	0.5168
Brugia malayi	ecdysteroid receptor	0.0404	0.5051	1
Loa Loa (eye worm)	nuclear Hormone Receptor family member	0.0404	0.5051	0.8851
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0017	0.009	0.0089
Echinococcus multilocularis	transcription factor btf3	0.0034	0.0313	0.0312
Brugia malayi	Pre-SET motif family protein	0.0203	0.2483	0.4915
Schistosoma mansoni	nuclear receptor nhr-48	0.019	0.2318	0.253
Echinococcus multilocularis	NADP dependent isocitrate dehydrogenase	0.0015	0.0074	0.0073
Brugia malayi	photoreceptor-specific nuclear receptor	0.0404	0.5051	1
Echinococcus granulosus	COUP TF:Svp nuclear hormone receptor	0.0404	0.5051	0.5648
Schistosoma mansoni	neuropeptide receptor	0.0017	0.009	0.0019
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0017	0.009	0.01
Loa Loa (eye worm)	nuclear hormone receptor family member nhr-14	0.0404	0.5051	0.8851
Mycobacterium ulcerans	glutamine synthetase	0.0455	0.5707	1
Brugia malayi	follicle stimulating hormone receptor	0.0017	0.009	0.0179
Loa Loa (eye worm)	hypothetical protein	0.019	0.2318	0.406
Echinococcus multilocularis	G protein coupled receptor 139	0.0017	0.009	0.0089
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Schistosoma mansoni	opsin-like receptor	0.0017	0.009	0.0019
Plasmodium vivax	SET domain protein, putative	0.003	0.0257	0.0325
Schistosoma mansoni	Tr4/Tr2 (homologue)	0.0404	0.5051	0.5613
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0017	0.009	0.0089
Echinococcus granulosus	hepatocyte nuclear factor 4 alpha	0.0404	0.5051	0.5648
Onchocerca volvulus	Bile acid receptor homolog	0.0404	0.5051	0.8833
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0302	0.0527
Echinococcus multilocularis	nuclear receptor 2DBD gamma	0.0404	0.5051	0.505
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0017	0.009	0.0019
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Echinococcus multilocularis	ecdysone induced protein 78C	0.0404	0.5051	0.505
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0017	0.009	0.0156
Brugia malayi	nuclear receptor NHR-67	0.019	0.2318	0.4588
Brugia malayi	Serotonin receptor	0.0017	0.009	0.0179
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0017	0.009	0.0019
Brugia malayi	Muscleblind-like protein	0.0145	0.1742	0.3448
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0017	0.009	0.01
Brugia malayi	hypothetical protein	0.0017	0.009	0.0179
Loa Loa (eye worm)	hypothetical protein	0.019	0.2318	0.406
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0017	0.009	0.0019
Echinococcus multilocularis	neuropeptides capa receptor	0.0017	0.009	0.0089
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.019	0.2318	0.2316
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0017	0.009	0.0089
Schistosoma mansoni	zinc finger protein	0.019	0.2318	0.253
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0017	0.009	0.0089
Entamoeba histolytica	glutamine synthetase, putative	0.0178	0.2164	1
Onchocerca volvulus		0.003	0.0257	0.0297
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0017	0.009	0.0089
Loa Loa (eye worm)	hypothetical protein	0.019	0.2318	0.406
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Echinococcus granulosus	dnaJ subfamily B	0.0398	0.4983	0.5572
Echinococcus granulosus	dro:myosuppressin receptor	0.0017	0.009	0.01
Echinococcus multilocularis	orexin receptor type 2	0.0017	0.009	0.0089
Loa Loa (eye worm)	Gln-2 protein	0.0455	0.5707	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0017	0.009	0.01
Schistosoma mansoni	glutamine synthetase bacteria	0.0178	0.2164	0.2358
Plasmodium vivax	glutamine synthetase, putative	0.0455	0.5707	1
Schistosoma mansoni	growth hormone secretagogue receptor	0.0017	0.009	0.0019
Loa Loa (eye worm)	hypothetical protein	0.019	0.2318	0.406
Loa Loa (eye worm)	hypothetical protein	0.019	0.2318	0.406
Schistosoma mansoni	cpg binding protein	0.003	0.0256	0.0205
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0017	0.009	0.0089
Brugia malayi	hypothetical protein	0.0213	0.261	0.5168
Echinococcus granulosus	5'partial\|histone lysine N methyltransferase SETDB2	0.0028	0.0236	0.0262
Echinococcus multilocularis	Nuclear hormone receptor HR96	0.019	0.2318	0.2316
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0015	0.0074	0.0072
Wolbachia endosymbiont of Brugia malayi	glutamine synthetase	0.0178	0.2164	0.5
Onchocerca volvulus	Glutamine synthetase homolog	0.0455	0.5707	1
Echinococcus granulosus	muscleblind protein	0.0145	0.1742	0.1947
Loa Loa (eye worm)	hypothetical protein	0.019	0.2318	0.406
Echinococcus granulosus	sex peptide receptor	0.0017	0.009	0.01
Toxoplasma gondii	histone lysine methyltransferase SET/SUV39	0.003	0.0257	0.0325
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Echinococcus granulosus	Nuclear hormone receptor HR96	0.019	0.2318	0.2591
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0017	0.009	0.0019
Loa Loa (eye worm)	hypothetical protein	0.0404	0.5051	0.8851
Brugia malayi	nuclear receptor NHR-88	0.0404	0.5051	1
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Echinococcus granulosus	7tm_1 domain containing protein	0.0017	0.009	0.01
Echinococcus multilocularis	Nuclear hormone receptor family member nhr 41	0.0404	0.5051	0.505
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0017	0.009	0.0019
Toxoplasma gondii	NAC domain-containing protein	0.0034	0.0313	0.0425
Loa Loa (eye worm)	hypothetical protein	0.0213	0.261	0.4573
Plasmodium falciparum	glutamine synthetase, putative	0.0455	0.5707	1
Echinococcus granulosus	nuclear receptor nhr 48	0.019	0.2318	0.2591
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0017	0.009	0.0019
Brugia malayi	steroid hormone receptor	0.0404	0.5051	1
Schistosoma mansoni	FTZ-F1 nuclear receptor-like protein	0.0404	0.5051	0.5613
Loa Loa (eye worm)	hypothetical protein	0.0404	0.5051	0.8851
Echinococcus multilocularis	nuclear receptor subfamily 4 group A	0.019	0.2318	0.2316
Echinococcus multilocularis	neuropeptide receptor	0.0017	0.009	0.0089
Schistosoma mansoni	nuclear receptor	0.019	0.2318	0.253
Echinococcus multilocularis	g-protein coupled receptor	0.0017	0.009	0.0089
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Loa Loa (eye worm)	hypothetical protein	0.0017	0.009	0.0156
Echinococcus multilocularis	FTZ F1 nuclear receptor protein	0.0404	0.5051	0.505
Brugia malayi	GnHR receptor homolog	0.0017	0.009	0.0179
Brugia malayi	nuclear hormone receptor	0.0404	0.5051	1
Loa Loa (eye worm)	neuropeptide F receptor	0.0017	0.009	0.0156
Echinococcus multilocularis	fmrfamide receptor	0.0017	0.009	0.0089

Activities

Activity type	Activity value	Assay description	Source	Reference
Ki (binding)	= 400 nM	Inhibition of human sst3 receptorexpressed in CHO cells	ChEMBL.	11327607
Ki (binding)	= 400 nM	Inhibition of human sst3 receptorexpressed in CHO cells	ChEMBL.	11327607
Ki (binding)	> 10000 nM	Inhibition of human sst1 receptor expressed in CHO cells	ChEMBL.	11327607
Ki (binding)	> 10000 nM	Inhibition of human sst2 receptor expressed in CHO cells	ChEMBL.	11327607
Ki (binding)	> 10000 nM	Inhibition of human sst4 receptor expressed in CHO cells	ChEMBL.	11327607
Ki (binding)	> 10000 nM	Inhibition of human sst5 receptor expressed in CHO cells	ChEMBL.	11327607
Ki (binding)	> 10000 nM	Inhibition of human sst1 receptor expressed in CHO cells	ChEMBL.	11327607
Ki (binding)	> 10000 nM	Inhibition of human sst2 receptor expressed in CHO cells	ChEMBL.	11327607
Ki (binding)	> 10000 nM	Inhibition of human sst4 receptor expressed in CHO cells	ChEMBL.	11327607
Ki (binding)	> 10000 nM	Inhibition of human sst5 receptor expressed in CHO cells	ChEMBL.	11327607

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL367716

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 307905