Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | phosphatidylinositol 3 kinase regulatory subunit | 0.004 | 0.2854 | 0.0644 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0051 | 0.4451 | 0.4451 |
Echinococcus granulosus | hypothetical protein | 0.004 | 0.2854 | 0.0644 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.3659 | 0.3659 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0046 | 0.3659 | 1 |
Echinococcus multilocularis | nervana 2 | 0.0069 | 0.6938 | 0.5991 |
Echinococcus multilocularis | SHC transforming protein 3 | 0.004 | 0.2854 | 0.0644 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.2713 | 0.2713 |
Schistosoma mansoni | tensin-related | 0.004 | 0.2854 | 0.0644 |
Entamoeba histolytica | protein kinase, putative | 0.004 | 0.2854 | 0.6411 |
Trypanosoma cruzi | calcium-transporting ATPase, putative | 0.0022 | 0.0279 | 0.0762 |
Brugia malayi | Variant SH3 domain containing protein | 0.004 | 0.2854 | 0.2854 |
Brugia malayi | E1-E2 ATPase family protein | 0.0029 | 0.1297 | 0.1297 |
Echinococcus multilocularis | tyrosine kinase | 0.0051 | 0.4451 | 0.2736 |
Schistosoma mansoni | slit-robo rho gtpase activating protein | 0.0039 | 0.2713 | 0.0459 |
Brugia malayi | SH2 domain containing protein | 0.0051 | 0.4451 | 0.4451 |
Schistosoma mansoni | chimerin-related rho-gtpase-activating protein | 0.004 | 0.2854 | 0.0644 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.3659 | 0.3659 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.009 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.009 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0051 | 0.4451 | 0.4451 |
Onchocerca volvulus | 0.004 | 0.2854 | 0.0334 | |
Brugia malayi | protein-tyrosine kinase | 0.0051 | 0.4451 | 0.4451 |
Leishmania major | P-type ATPase, putative | 0.0037 | 0.2362 | 0.4509 |
Schistosoma mansoni | signal transducing adapter molecule (stam) | 0.0039 | 0.2713 | 0.0459 |
Echinococcus multilocularis | breast cancer anti estrogen resistance protein | 0.0039 | 0.2713 | 0.0459 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.4451 | 0.4451 |
Echinococcus multilocularis | rho guanine nucleotide exchange factor 7 | 0.0039 | 0.2713 | 0.0459 |
Echinococcus multilocularis | tyrosine protein kinase Abl | 0.009 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein kinase lyn tyrosine protein kinase blk | 0.009 | 1 | 1 |
Echinococcus granulosus | c src tyrosine kinase | 0.009 | 1 | 1 |
Echinococcus granulosus | sarco:endoplasmic reticulum calcium ATPase | 0.0046 | 0.3659 | 0.1698 |
Brugia malayi | SH2 domain containing protein | 0.004 | 0.2854 | 0.2854 |
Onchocerca volvulus | 0.0069 | 0.6938 | 1 | |
Echinococcus granulosus | tyrosine kinase|tyrosine protein kinase Fyn | 0.0051 | 0.4451 | 0.2736 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.2713 | 0.5995 |
Entamoeba histolytica | calcium-transporting P-type ATPase, putative | 0.0046 | 0.3659 | 0.8219 |
Echinococcus granulosus | Spectrin alpha actinin | 0.0039 | 0.2713 | 0.0459 |
Echinococcus multilocularis | sarco:endoplasmic reticulum calcium ATPase | 0.0046 | 0.3659 | 0.1698 |
Schistosoma mansoni | GTPase activating protein | 0.004 | 0.2854 | 0.0644 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0037 | 0.2362 | 0.4509 |
Toxoplasma gondii | plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 | 0.0037 | 0.2362 | 0.6455 |
Schistosoma mansoni | development and differentiation-enhancing factor ddef | 0.0039 | 0.2713 | 0.0459 |
Trypanosoma brucei | P-type H+-ATPase, putative | 0.0029 | 0.1297 | 0.3012 |
Entamoeba histolytica | unconventional myosin IB | 0.0039 | 0.2713 | 0.6094 |
Echinococcus granulosus | SH2 motif | 0.004 | 0.2854 | 0.0644 |
Echinococcus multilocularis | suppressor of cytokine signaling 7 | 0.004 | 0.2854 | 0.0644 |
Onchocerca volvulus | 0.004 | 0.2854 | 0.0334 | |
Entamoeba histolytica | SH2 domain containing protein | 0.004 | 0.2854 | 0.6411 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.2713 | 0.6094 |
Echinococcus granulosus | nervana 2 | 0.0069 | 0.6938 | 0.5991 |
Brugia malayi | Variant SH3 domain containing protein | 0.0039 | 0.2713 | 0.2713 |
Trypanosoma cruzi | Calcium ATPase SERCA-like | 0.0046 | 0.3659 | 1 |
Trichomonas vaginalis | cation-transporting ATPase, putative | 0.0046 | 0.3659 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Src64B | 0.009 | 1 | 1 |
Mycobacterium tuberculosis | Possible metal cation transporting P-type ATPase CtpH | 0.0031 | 0.1576 | 0.5 |
Entamoeba histolytica | plasma membrane calcium ion-transporting ATPase, putative | 0.0026 | 0.0823 | 0.1848 |
Brugia malayi | SH2 domain containing protein | 0.0051 | 0.4451 | 0.4451 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0069 | 0.6938 | 0.5991 |
Echinococcus multilocularis | sodium:potassium transporting ATPase subunit | 0.0069 | 0.6938 | 0.5991 |
Echinococcus granulosus | tyrosine protein kinase Btk29A | 0.009 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0279 | 0.0279 |
Loa Loa (eye worm) | TK protein kinase | 0.0051 | 0.4451 | 0.4451 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.004 | 0.2854 | 0.2854 |
Brugia malayi | Protein kinase domain containing protein | 0.0051 | 0.4451 | 0.4451 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0051 | 0.4451 | 0.4451 |
Echinococcus granulosus | tyrosine protein kinase Srms | 0.0051 | 0.4451 | 0.2736 |
Echinococcus granulosus | 3'partial|tyrosine protein kinase Fgr | 0.009 | 1 | 1 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0046 | 0.3659 | 1 |
Entamoeba histolytica | BAR/SH3 domain containing protein | 0.0039 | 0.2713 | 0.6094 |
Echinococcus multilocularis | tyrosine protein kinase Src42A | 0.004 | 0.2854 | 0.0644 |
Brugia malayi | haloacid dehalogenase-like hydrolase family protein | 0.0026 | 0.0823 | 0.0823 |
Echinococcus granulosus | tensin C1 domain containing phosphatase | 0.004 | 0.2854 | 0.0644 |
Loa Loa (eye worm) | E1-E2 ATPase | 0.0029 | 0.1297 | 0.1297 |
Echinococcus multilocularis | tyrosine protein kinase Fps85D | 0.0051 | 0.4451 | 0.2736 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0046 | 0.3659 | 1 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.009 | 1 | 1 |
Onchocerca volvulus | Suppressor of cytokine signaling at 36E homolog | 0.004 | 0.2854 | 0.0334 |
Schistosoma mansoni | sorbin | 0.0039 | 0.2713 | 0.0459 |
Echinococcus granulosus | expressed protein | 0.0039 | 0.2713 | 0.0459 |
Trichomonas vaginalis | cation-transporting ATPase, putative | 0.0046 | 0.3659 | 1 |
Echinococcus granulosus | tyrosine protein kinase Fps85D | 0.0051 | 0.4451 | 0.2736 |
Echinococcus multilocularis | fch and double sh3 domains protein 2 | 0.0039 | 0.2713 | 0.0459 |
Echinococcus granulosus | nervana 2 | 0.0069 | 0.6938 | 0.5991 |
Schistosoma mansoni | suppressor of cytokine signaling | 0.004 | 0.2854 | 0.0644 |
Echinococcus multilocularis | Spectrin alpha actinin | 0.0039 | 0.2713 | 0.0459 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.2713 | 0.2713 |
Loa Loa (eye worm) | STAT protein | 0.004 | 0.2854 | 0.2854 |
Brugia malayi | Variant SH3 domain containing protein | 0.0039 | 0.2713 | 0.2713 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0051 | 0.4451 | 0.4451 |
Echinococcus granulosus | hematopoietic lineage cell specific protein | 0.0039 | 0.2713 | 0.0459 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.2713 | 0.7415 |
Brugia malayi | SH2 domain containing protein | 0.004 | 0.2854 | 0.2854 |
Brugia malayi | Peripheral plasma membrane protein CASK | 0.0039 | 0.2713 | 0.2713 |
Loa Loa (eye worm) | calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type | 0.0022 | 0.0279 | 0.0279 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2854 | 0.2854 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.2713 | 0.5995 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0069 | 0.6938 | 0.5991 |
Brugia malayi | Spectrin alpha chain | 0.0039 | 0.2713 | 0.2713 |
Brugia malayi | Protein kinase domain containing protein | 0.0051 | 0.4451 | 0.4451 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase src | 0.009 | 1 | 1 |
Schistosoma mansoni | tensin | 0.004 | 0.2854 | 0.0644 |
Brugia malayi | Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type | 0.0037 | 0.2362 | 0.2362 |
Echinococcus granulosus | fch and double sh3 domains protein 2 | 0.0039 | 0.2713 | 0.0459 |
Schistosoma mansoni | tyrosine kinase | 0.009 | 1 | 1 |
Brugia malayi | SH3 domain containing protein | 0.0039 | 0.2713 | 0.2713 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.0079 | 0.8403 | 0.8403 |
Entamoeba histolytica | SH2-protein kinase domain containing protein | 0.0051 | 0.4451 | 1 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.004 | 0.2854 | 0.0644 |
Brugia malayi | Variant SH3 domain containing protein | 0.0039 | 0.2713 | 0.2713 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.009 | 1 | 1 |
Schistosoma mansoni | sorting nexin | 0.0039 | 0.2713 | 0.0459 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0039 | 0.2713 | 0.6094 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.2713 | 0.0459 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.2713 | 0.6094 |
Entamoeba histolytica | protein kinase, putative | 0.0039 | 0.2713 | 0.6094 |
Brugia malayi | hypothetical protein | 0.004 | 0.2854 | 0.2854 |
Echinococcus granulosus | plasma membrane calcium transporting ATPase 2 | 0.0046 | 0.3659 | 0.1698 |
Loa Loa (eye worm) | p53BP2 | 0.0039 | 0.2713 | 0.2713 |
Schistosoma mansoni | sodium/potassium-dependent atpase beta subunit | 0.0069 | 0.6938 | 0.5991 |
Trypanosoma brucei | conserved protein | 0.0039 | 0.2713 | 0.7201 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0039 | 0.2713 | 0.6094 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2854 | 0.2854 |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.8403 | 0.8403 |
Echinococcus granulosus | tyrosine protein kinase Blk | 0.0051 | 0.4451 | 0.2736 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0051 | 0.4451 | 0.4451 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0046 | 0.3659 | 1 |
Onchocerca volvulus | 0.0051 | 0.4451 | 0.4115 | |
Schistosoma mansoni | sodium / potassium ATPase beta chain | 0.0069 | 0.6938 | 0.5991 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.2713 | 0.7415 |
Echinococcus multilocularis | Tetracycline resistance leader peptide, TetL | 0.0046 | 0.3659 | 0.1698 |
Echinococcus granulosus | SH2 motif | 0.004 | 0.2854 | 0.0644 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2854 | 0.2854 |
Echinococcus multilocularis | tyrosine protein kinase shark | 0.0051 | 0.4451 | 0.2736 |
Echinococcus granulosus | SHC transforming protein 3 | 0.004 | 0.2854 | 0.0644 |
Schistosoma mansoni | formin binding protein and related proteins | 0.0039 | 0.2713 | 0.0459 |
Onchocerca volvulus | Suppressor of cytokine signaling 7 homolog | 0.004 | 0.2854 | 0.0334 |
Schistosoma mansoni | dreadlocks/dock | 0.0039 | 0.2713 | 0.0459 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2854 | 0.2854 |
Brugia malayi | Protein kinase domain containing protein | 0.0051 | 0.4451 | 0.4451 |
Brugia malayi | Sodium/potassium-transporting ATPase alpha chain, putative | 0.0031 | 0.1576 | 0.1576 |
Brugia malayi | Src substrate cortactin | 0.0039 | 0.2713 | 0.2713 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.009 | 1 | 1 |
Echinococcus granulosus | epidermal growth factor receptor kinase | 0.0039 | 0.2713 | 0.0459 |
Schistosoma mansoni | proto-oncogene tyrosine-protein kinase abl1 | 0.0079 | 0.8403 | 0.7909 |
Echinococcus multilocularis | tyrosine protein kinase Srms | 0.0051 | 0.4451 | 0.2736 |
Schistosoma mansoni | apoptosis stimulating of P53 | 0.0039 | 0.2713 | 0.0459 |
Brugia malayi | SRC-1 | 0.009 | 1 | 1 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.004 | 0.2854 | 0.0644 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0051 | 0.4451 | 0.4451 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2854 | 0.2854 |
Trichomonas vaginalis | cation-transporting ATPase, putative | 0.0046 | 0.3659 | 1 |
Trypanosoma cruzi | plasma membrane Ca2+ ATPase | 0.0046 | 0.3659 | 1 |
Brugia malayi | Variant SH3 domain containing protein | 0.0079 | 0.8403 | 0.8403 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.2713 | 0.2713 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.2713 | 0.5995 |
Loa Loa (eye worm) | Na,K-ATPase alpha subunit | 0.0046 | 0.3659 | 0.3659 |
Brugia malayi | SH2 domain containing protein | 0.004 | 0.2854 | 0.2854 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2854 | 0.2854 |
Echinococcus multilocularis | nostrin | 0.0039 | 0.2713 | 0.0459 |
Echinococcus multilocularis | SH2 motif | 0.004 | 0.2854 | 0.0644 |
Trypanosoma cruzi | plasma membrane Ca2+ ATPase | 0.0046 | 0.3659 | 1 |
Echinococcus multilocularis | intersectin 2 | 0.0039 | 0.2713 | 0.0459 |
Echinococcus multilocularis | suppressor of cytokine signaling 6 | 0.004 | 0.2854 | 0.0644 |
Brugia malayi | protein-tyrosine kinase | 0.0039 | 0.2713 | 0.2713 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.2713 | 0.2713 |
Echinococcus multilocularis | transfer RNA-Ala | 0.0039 | 0.2713 | 0.0459 |
Echinococcus granulosus | endophilin A3 | 0.0039 | 0.2713 | 0.0459 |
Trichomonas vaginalis | cation-transporting ATPase fungi, putative | 0.0046 | 0.3659 | 1 |
Echinococcus granulosus | signal transduction protein lnk realted | 0.004 | 0.2854 | 0.0644 |
Leishmania major | vacuolar-type Ca2 -ATPase, putative | 0.0046 | 0.3659 | 1 |
Schistosoma mansoni | sodium/potassium-dependent atpase beta subunit | 0.0069 | 0.6938 | 0.5991 |
Echinococcus granulosus | SH2 domain containing protein 7 | 0.004 | 0.2854 | 0.0644 |
Trichomonas vaginalis | plasma membrane calcium-transporting ATPase, putative | 0.0046 | 0.3659 | 1 |
Schistosoma mansoni | ATPase | 0.0046 | 0.3659 | 0.1698 |
Echinococcus multilocularis | calcium transporting ATPase type 2C member | 0.0046 | 0.3659 | 0.1698 |
Schistosoma mansoni | sh3-containing grb2-like protein 1 (endophilin II) | 0.0039 | 0.2713 | 0.0459 |
Schistosoma mansoni | serine/threonine protein kinase | 0.005 | 0.431 | 0.2551 |
Loa Loa (eye worm) | thyroid receptor interactor | 0.0039 | 0.2713 | 0.2713 |
Onchocerca volvulus | 0.004 | 0.2854 | 0.0334 | |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0051 | 0.4451 | 0.4451 |
Leishmania major | calcium-translocating P-type ATPase | 0.0046 | 0.3659 | 1 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.009 | 1 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.009 | 1 | 1 |
Echinococcus granulosus | sodium:potassium transporting ATPase subunit | 0.0069 | 0.6938 | 0.5991 |
Entamoeba histolytica | Plasma membrane calcium-transporting ATPase, putative | 0.0046 | 0.3659 | 0.8219 |
Leishmania major | hypothetical protein, conserved | 0.0039 | 0.2713 | 0.5995 |
Trypanosoma cruzi | calcium motive p-type ATPase, putative | 0.0037 | 0.2362 | 0.6455 |
Echinococcus multilocularis | epidermal growth factor receptor kinase | 0.0039 | 0.2713 | 0.0459 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2854 | 0.2854 |
Schistosoma mansoni | adapter molecule crk | 0.0079 | 0.8403 | 0.7909 |
Onchocerca volvulus | 0.0051 | 0.4451 | 0.4115 | |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.009 | 1 | 1 |
Brugia malayi | cytokine inducible SH2-containing protein 5 | 0.004 | 0.2854 | 0.2854 |
Echinococcus multilocularis | nervana 2 | 0.0069 | 0.6938 | 0.5991 |
Entamoeba histolytica | plasma membrane calcium-transporting ATPase 1, putative | 0.0026 | 0.0823 | 0.1848 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.2713 | 0.5995 |
Brugia malayi | SH2 domain containing protein | 0.004 | 0.2854 | 0.2854 |
Schistosoma mansoni | chimerin-related rho-gtpase-activating protein | 0.004 | 0.2854 | 0.0644 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0069 | 0.6938 | 0.5991 |
Echinococcus granulosus | NCK adaptor protein | 0.0079 | 0.8403 | 0.7909 |
Echinococcus granulosus | breast cancer anti estrogen resistance protein | 0.0039 | 0.2713 | 0.0459 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.2713 | 0.6094 |
Echinococcus multilocularis | suppressor of cytokine signaling 7 | 0.004 | 0.2854 | 0.0644 |
Brugia malayi | SH2 domain containing protein | 0.004 | 0.2854 | 0.2854 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2854 | 0.2854 |
Schistosoma mansoni | dynamin-associated protein | 0.0039 | 0.2713 | 0.0459 |
Brugia malayi | Protein kinase domain containing protein | 0.0051 | 0.4451 | 0.4451 |
Schistosoma mansoni | C-fyn | 0.0039 | 0.2713 | 0.0459 |
Brugia malayi | Variant SH3 domain containing protein | 0.0079 | 0.8403 | 0.8403 |
Schistosoma mansoni | vav2 | 0.004 | 0.2854 | 0.0644 |
Echinococcus multilocularis | tensin | 0.004 | 0.2854 | 0.0644 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.2713 | 0.0459 |
Schistosoma mansoni | tyrosine kinase | 0.0051 | 0.4451 | 0.2736 |
Onchocerca volvulus | 0.004 | 0.2854 | 0.0334 | |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.6938 | 0.6938 |
Schistosoma mansoni | cell polarity protein | 0.0039 | 0.2713 | 0.0459 |
Loa Loa (eye worm) | SH2 domain-containing protein | 0.004 | 0.2854 | 0.2854 |
Echinococcus multilocularis | tensin | 0.004 | 0.2854 | 0.0644 |
Mycobacterium ulcerans | metal cation-transporting p-type ATPase F, CtpF | 0.0046 | 0.3659 | 1 |
Plasmodium falciparum | non-SERCA-type Ca2+ -transporting P-ATPase | 0.0046 | 0.3659 | 1 |
Echinococcus multilocularis | SH2 motif | 0.004 | 0.2854 | 0.0644 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0051 | 0.4451 | 0.4451 |
Onchocerca volvulus | 0.0069 | 0.6938 | 1 | |
Trypanosoma brucei | calcium motive p-type ATPase, putative | 0.0037 | 0.2362 | 0.6163 |
Schistosoma mansoni | tensin | 0.004 | 0.2854 | 0.0644 |
Echinococcus multilocularis | proto oncogene tyrosine protein kinase LCK | 0.009 | 1 | 1 |
Echinococcus granulosus | tensin | 0.004 | 0.2854 | 0.0644 |
Onchocerca volvulus | 0.0051 | 0.4451 | 0.4115 | |
Entamoeba histolytica | BAR/SH3 domain containing protein | 0.0039 | 0.2713 | 0.6094 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.2713 | 0.6094 |
Loa Loa (eye worm) | SRC-1 | 0.009 | 1 | 1 |
Loa Loa (eye worm) | cytokine inducible SH2-containing protein 5 | 0.004 | 0.2854 | 0.2854 |
Loa Loa (eye worm) | sex muscle abnormal protein 5 | 0.0079 | 0.8403 | 0.8403 |
Echinococcus multilocularis | N chimaerin | 0.004 | 0.2854 | 0.0644 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.004 | 0.2854 | 0.2854 |
Echinococcus multilocularis | slit robo rho gtpase activating protein 1 | 0.0039 | 0.2713 | 0.0459 |
Echinococcus multilocularis | growth factor receptor bound protein 2 | 0.0079 | 0.8403 | 0.7909 |
Loa Loa (eye worm) | guanylate kinase | 0.0039 | 0.2713 | 0.2713 |
Trypanosoma brucei | vacuolar-type Ca2+-ATPase 2 | 0.0046 | 0.3659 | 1 |
Brugia malayi | SH2 domain containing protein | 0.004 | 0.2854 | 0.2854 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.2713 | 0.6094 |
Echinococcus multilocularis | SH2 domain containing adapter protein F | 0.004 | 0.2854 | 0.0644 |
Brugia malayi | STAT protein, DNA binding domain containing protein | 0.004 | 0.2854 | 0.2854 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.2713 | 0.2713 |
Trichomonas vaginalis | neutrophil cytosolic factor 2, neutrophil NADPH oxidase factor, putative | 0.0039 | 0.2713 | 0.5995 |
Brugia malayi | Na,K-ATPase alpha subunit | 0.0046 | 0.3659 | 0.3659 |
Echinococcus granulosus | nostrin | 0.0039 | 0.2713 | 0.0459 |
Loa Loa (eye worm) | TK/ABL protein kinase | 0.0051 | 0.4451 | 0.4451 |
Brugia malayi | Protein kinase domain containing protein | 0.0051 | 0.4451 | 0.4451 |
Mycobacterium leprae | PROBABLE CATION-TRANSPORTER ATPASE I CTPI | 0.0031 | 0.1576 | 0.5 |
Echinococcus granulosus | calcium transporting ATPase type 2C member | 0.0046 | 0.3659 | 0.1698 |
Schistosoma mansoni | protein tyrosine phosphatase n11 (shp2) | 0.004 | 0.2854 | 0.0644 |
Brugia malayi | Variant SH3 domain containing protein | 0.0039 | 0.2713 | 0.2713 |
Echinococcus multilocularis | SH2 domain containing protein 7 | 0.004 | 0.2854 | 0.0644 |
Echinococcus multilocularis | arf GAP with SH3 domain, ANK repeat and PH | 0.0039 | 0.2713 | 0.0459 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.2713 | 0.6094 |
Trypanosoma brucei | P-type H+-ATPase, putative | 0.0029 | 0.1297 | 0.3012 |
Echinococcus granulosus | SH2 domain containing adapter protein F | 0.004 | 0.2854 | 0.0644 |
Echinococcus multilocularis | signal transduction protein lnk realted | 0.004 | 0.2854 | 0.0644 |
Echinococcus granulosus | tyrosine protein kinase Fyn | 0.009 | 1 | 1 |
Loa Loa (eye worm) | SH2 domain-containing protein | 0.004 | 0.2854 | 0.2854 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.2713 | 0.5995 |
Brugia malayi | Myosin tail family protein | 0.0039 | 0.2713 | 0.2713 |
Onchocerca volvulus | 0.004 | 0.2854 | 0.0334 | |
Brugia malayi | Variant SH3 domain containing protein | 0.0039 | 0.2713 | 0.2713 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.004 | 0.2854 | 0.0644 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2854 | 0.2854 |
Trypanosoma brucei | vacuolar-type Ca2+-ATPase 1 | 0.0046 | 0.3659 | 1 |
Echinococcus multilocularis | endophilin A3 | 0.0039 | 0.2713 | 0.0459 |
Brugia malayi | Fes/CIP4 homology domain containing protein | 0.0039 | 0.2713 | 0.2713 |
Schistosoma mansoni | Na+/K+ transporting ATPase subunit alpha | 0.0046 | 0.3659 | 0.1698 |
Loa Loa (eye worm) | protein-tyrosine kinase | 0.0039 | 0.2713 | 0.2713 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.2854 | 0.0644 |
Schistosoma mansoni | tensin-related | 0.004 | 0.2854 | 0.0644 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0069 | 0.6938 | 0.5991 |
Onchocerca volvulus | 0.004 | 0.2854 | 0.0334 | |
Echinococcus multilocularis | NCK adaptor protein | 0.0079 | 0.8403 | 0.7909 |
Echinococcus multilocularis | expressed protein | 0.0039 | 0.2713 | 0.0459 |
Giardia lamblia | Plasma membrane calcium-transporting ATPase 2 | 0.0046 | 0.3659 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.2713 | 0.5995 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2854 | 0.2854 |
Trypanosoma cruzi | P-type H+-ATPase, putative | 0.0029 | 0.1297 | 0.3545 |
Echinococcus granulosus | tyrosine protein kinase Lyn | 0.009 | 1 | 1 |
Brugia malayi | tRNA modification GTPase TrmE family protein | 0.004 | 0.2854 | 0.2854 |
Trypanosoma cruzi | calcium motive p-type ATPase, putative | 0.0037 | 0.2362 | 0.6455 |
Echinococcus granulosus | src region | 0.0039 | 0.2713 | 0.0459 |
Brugia malayi | Tensin | 0.004 | 0.2854 | 0.2854 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0051 | 0.4451 | 0.4451 |
Schistosoma mansoni | run and tbc1 domain containing | 0.0039 | 0.2713 | 0.0459 |
Echinococcus granulosus | tyrosine protein kinase ABL1 | 0.0051 | 0.4451 | 0.2736 |
Echinococcus granulosus | nervana 2 | 0.0069 | 0.6938 | 0.5991 |
Echinococcus multilocularis | phosphatidylinositol 3 kinase regulatory subunit | 0.004 | 0.2854 | 0.0644 |
Brugia malayi | Sex muscle abnormal protein 5 | 0.0079 | 0.8403 | 0.8403 |
Schistosoma mansoni | suppressor of cytokine signaling | 0.004 | 0.2854 | 0.0644 |
Leishmania major | calcium motive p-type ATPase, putative | 0.0037 | 0.2362 | 0.4509 |
Schistosoma mansoni | tyrosine-protein kinase zap-70 | 0.004 | 0.2854 | 0.0644 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0051 | 0.4451 | 0.4451 |
Mycobacterium ulcerans | metal cation transporter p-type ATPase a | 0.0046 | 0.3659 | 1 |
Echinococcus multilocularis | guanine nucleotide exchange factor VAV2 | 0.004 | 0.2854 | 0.0644 |
Echinococcus granulosus | tyrosine protein kinase shark | 0.0051 | 0.4451 | 0.2736 |
Echinococcus multilocularis | tyrosine protein kinase Blk | 0.0051 | 0.4451 | 0.2736 |
Echinococcus multilocularis | 0.004 | 0.2854 | 0.0644 | |
Toxoplasma gondii | P-type ATPase4, putative | 0.0046 | 0.3659 | 1 |
Brugia malayi | RhoGAP domain containing protein | 0.004 | 0.2854 | 0.2854 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.0039 | 0.2713 | 0.2713 |
Echinococcus granulosus | guanine nucleotide exchange factor VAV2 | 0.004 | 0.2854 | 0.0644 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.004 | 0.2854 | 0.0644 |
Leishmania major | vacuolar-type Ca2 -ATPase, putative | 0.0046 | 0.3659 | 1 |
Brugia malayi | Guanylate kinase family protein | 0.0039 | 0.2713 | 0.2713 |
Loa Loa (eye worm) | calcium ATPase | 0.0026 | 0.0823 | 0.0823 |
Schistosoma mansoni | transmemberane protein | 0.0069 | 0.6938 | 0.5991 |
Brugia malayi | SH2 domain containing protein | 0.004 | 0.2854 | 0.2854 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.004 | 0.2854 | 0.2854 |
Toxoplasma gondii | calcium-translocating P-type ATPase, PMCA-type protein | 0.0046 | 0.3659 | 1 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.004 | 0.2854 | 0.0644 |
Loa Loa (eye worm) | sodium/potassium-transporting ATPase subunit alpha | 0.0031 | 0.1576 | 0.1576 |
Brugia malayi | Variant SH3 domain containing protein | 0.004 | 0.2854 | 0.2854 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.2713 | 0.2713 |
Schistosoma mansoni | sodium/potassium-dependent atpase beta subunit | 0.0069 | 0.6938 | 0.5991 |
Echinococcus multilocularis | nervana 2 | 0.0069 | 0.6938 | 0.5991 |
Schistosoma mansoni | eps8-related protein | 0.0039 | 0.2713 | 0.0459 |
Echinococcus multilocularis | tyrosine protein kinase Fgr | 0.009 | 1 | 1 |
Entamoeba histolytica | Plasma membrane calcium-transporting ATPase, putative | 0.0046 | 0.3659 | 0.8219 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2854 | 0.2854 |
Brugia malayi | Variant SH3 domain containing protein | 0.0039 | 0.2713 | 0.2713 |
Trypanosoma cruzi | paraflagellar rod protein 5, putative | 0.0039 | 0.2713 | 0.7415 |
Echinococcus granulosus | intersectin 2 | 0.0039 | 0.2713 | 0.0459 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2854 | 0.2854 |
Schistosoma mansoni | shc transforming protein | 0.004 | 0.2854 | 0.0644 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.2713 | 0.2713 |
Echinococcus granulosus | N chimaerin | 0.004 | 0.2854 | 0.0644 |
Echinococcus granulosus | tyrosine kinase | 0.0051 | 0.4451 | 0.2736 |
Onchocerca volvulus | 0.0051 | 0.4451 | 0.4115 | |
Trichomonas vaginalis | p67phox protein, putative | 0.0039 | 0.2713 | 0.5995 |
Echinococcus granulosus | rho guanine nucleotide exchange factor 7 | 0.0039 | 0.2713 | 0.0459 |
Schistosoma mansoni | tyrosine kinase | 0.009 | 1 | 1 |
Echinococcus granulosus | tyrosine kinase | 0.0051 | 0.4451 | 0.2736 |
Toxoplasma gondii | P-type ATPase PMA1 | 0.0029 | 0.1297 | 0.3545 |
Loa Loa (eye worm) | RhoGAP domain-containing protein | 0.004 | 0.2854 | 0.2854 |
Echinococcus granulosus | nervana 2 | 0.0069 | 0.6938 | 0.5991 |
Brugia malayi | Probable calcium-transporting ATPase KIAA0703 | 0.0022 | 0.0279 | 0.0279 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0079 | 0.8403 | 0.7909 |
Schistosoma mansoni | tyrosine kinase | 0.0051 | 0.4451 | 0.2736 |
Echinococcus multilocularis | tyrosine protein kinase Btk29A | 0.009 | 1 | 1 |
Schistosoma mansoni | tensin | 0.004 | 0.2854 | 0.0644 |
Echinococcus multilocularis | tyrosine protein kinase Fyn | 0.0051 | 0.4451 | 0.2736 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.2713 | 0.6094 |
Echinococcus granulosus | arf GAP with SH3 domain ANK repeat and PH | 0.0039 | 0.2713 | 0.0459 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.2854 | 0.0644 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0039 | 0.2713 | 0.5995 |
Toxoplasma gondii | sarco/endoplasmic reticulum Ca2+-ATPase | 0.0046 | 0.3659 | 1 |
Loa Loa (eye worm) | protein kinase C and casein kinase substrate in neurons protein 2 | 0.0039 | 0.2713 | 0.2713 |
Trypanosoma cruzi | P-type H+-ATPase, putative | 0.0029 | 0.1297 | 0.3545 |
Entamoeba histolytica | SH2-protein kinase domain containing protein | 0.004 | 0.2854 | 0.6411 |
Echinococcus granulosus | growth factor receptor bound protein 2 | 0.0079 | 0.8403 | 0.7909 |
Trypanosoma brucei | vacuolar-type Ca2+-ATPase, putative | 0.0046 | 0.3659 | 1 |
Echinococcus granulosus | proto oncogene tyrosine protein kinase LCK | 0.009 | 1 | 1 |
Schistosoma mansoni | SH2A | 0.004 | 0.2854 | 0.0644 |
Schistosoma mansoni | nck2/grb4 | 0.0079 | 0.8403 | 0.7909 |
Trypanosoma brucei | calcium-translocating P-type ATPase | 0.0037 | 0.2362 | 0.6163 |
Entamoeba histolytica | Plasma membrane calcium-transporting ATPase, putative | 0.0046 | 0.3659 | 0.8219 |
Brugia malayi | Membrane calcium atpase protein 3 | 0.0037 | 0.2362 | 0.2362 |
Echinococcus multilocularis | hematopoietic lineage cell specific protein | 0.0039 | 0.2713 | 0.0459 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.2713 | 0.6094 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0039 | 0.2713 | 0.7415 |
Schistosoma mansoni | signal transduction protein lnk-related | 0.004 | 0.2854 | 0.0644 |
Echinococcus multilocularis | c src tyrosine kinase | 0.009 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2854 | 0.2854 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0069 | 0.6938 | 0.5991 |
Schistosoma mansoni | ATPase | 0.0046 | 0.3659 | 0.1698 |
Echinococcus granulosus | tyrosine protein kinase Src42A | 0.009 | 1 | 1 |
Onchocerca volvulus | 0.0051 | 0.4451 | 0.4115 | |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.2713 | 0.2713 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.6938 | 0.6938 |
Echinococcus granulosus | expressed conserved protein | 0.004 | 0.2854 | 0.0644 |
Echinococcus granulosus | suppressor of cytokine signaling 6 | 0.004 | 0.2854 | 0.0644 |
Echinococcus granulosus | slit robo rho gtpase activating protein 1 | 0.0039 | 0.2713 | 0.0459 |
Loa Loa (eye worm) | TK/FER protein kinase | 0.0051 | 0.4451 | 0.4451 |
Onchocerca volvulus | 0.0046 | 0.3659 | 0.2239 | |
Plasmodium vivax | calcium-transporting ATPase, putative | 0.0046 | 0.3659 | 0.5 |
Echinococcus granulosus | tyrosine protein kinase Src64B | 0.009 | 1 | 1 |
Loa Loa (eye worm) | SH2 domain-containing protein | 0.004 | 0.2854 | 0.2854 |
Echinococcus multilocularis | tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase | 0.009 | 1 | 1 |
Echinococcus multilocularis | nervana 2 | 0.0069 | 0.6938 | 0.5991 |
Schistosoma mansoni | Dab2-interacting protein-like | 0.0039 | 0.2713 | 0.0459 |
Onchocerca volvulus | 0.0051 | 0.4451 | 0.4115 | |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0069 | 0.6938 | 0.5991 |
Echinococcus multilocularis | tyrosine protein kinase ABL1 | 0.0051 | 0.4451 | 0.2736 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.2713 | 0.2713 |
Echinococcus granulosus | suppressor of cytokine signaling 7 | 0.004 | 0.2854 | 0.0644 |
Schistosoma mansoni | growth factor receptor-bound protein | 0.0079 | 0.8403 | 0.7909 |
Echinococcus multilocularis | SH2 motif | 0.004 | 0.2854 | 0.0644 |
Leishmania major | calcium-transporting ATPase, putative | 0.0037 | 0.2362 | 0.4509 |
Plasmodium vivax | P-type ATPase4, putative | 0.0046 | 0.3659 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.2854 | 0.2854 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
EC90 (functional) | = 0.63 ug ml-1 | In vitro effective concentrationof the compound causing 90%reduction in residualmycobacterium tuberculosis growth after 7 days compared to untreated control | ChEMBL. | 15771444 |
EC90 (functional) | = 0.63 ug ml-1 | In vitro effective concentrationof the compound causing 90%reduction in residualmycobacterium tuberculosis growth after 7 days compared to untreated control | ChEMBL. | 15771444 |
EC99 (functional) | = 5.99 ug ml-1 | In vitro effective concentrationof the compound causing 99%reduction in residualmycobacterium tuberculosis growth after 7 days compared to untreated control | ChEMBL. | 15771444 |
EC99 (functional) | = 5.99 ug ml-1 | In vitro effective concentrationof the compound causing 99%reduction in residualmycobacterium tuberculosis growth after 7 days compared to untreated control | ChEMBL. | 15771444 |
IC50 (ADMET) | = 4 ug ml-1 | Compound was tested for cytotoxicity in Vero cells | ChEMBL. | 15771444 |
MIC (functional) | < 0.2 ug ml-1 | In vitro actual minimum inhibitoryconcentration value of thecompound was determined againstMycobacterium tuberculosis | ChEMBL. | 15771444 |
MIC (functional) | < 0.2 ug ml-1 | In vitro actual minimum inhibitoryconcentration value of thecompound was determined againstMycobacterium tuberculosis | ChEMBL. | 15771444 |
Ratio (functional) | > 3.15 ug ml-1 | In vitro ratio of EC90 and MIC valueof the compound was determined | ChEMBL. | 15771444 |
Ratio (functional) | > 3.15 ug ml-1 | In vitro ratio of EC90 and MIC valueof the compound was determined | ChEMBL. | 15771444 |
SI (ADMET) | > 20 ug ml-1 | Selectivity index (ratio of IC50 and MIC) value of the compound was determined | ChEMBL. | 15771444 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.