Detailed information for compound 311441

Basic information

Technical information
  • TDR Targets ID: 311441
  • Name: 4-N-(1,3-benzothiazol-6-yl)-6-methoxy-2-N-(2- phenylpropan-2-yl)-1,3,5-triazine-2,4-diamine
  • MW: 392.477 | Formula: C20H20N6OS
  • H donors: 2 H acceptors: 4 LogP: 5.01 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1nc(Nc2ccc3c(c2)scn3)nc(n1)NC(c1ccccc1)(C)C
  • InChi: 1S/C20H20N6OS/c1-20(2,13-7-5-4-6-8-13)26-18-23-17(24-19(25-18)27-3)22-14-9-10-15-16(11-14)28-12-21-15/h4-12H,1-3H3,(H2,22,23,24,25,26)
  • InChiKey: AKDWJKHIBCIRSA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N4-(1,3-benzothiazol-6-yl)-6-methoxy-N2-(1-methyl-1-phenyl-ethyl)-1,3,5-triazine-2,4-diamine
  • N4-(1,3-benzothiazol-6-yl)-6-methoxy-N2-(1-methyl-1-phenylethyl)-1,3,5-triazine-2,4-diamine
  • N4-(1,3-benzothiazol-6-yl)-6-methoxy-N2-(2-phenylpropan-2-yl)-1,3,5-triazine-2,4-diamine
  • 1,3-benzothiazol-6-yl-[4-(cumylamino)-6-methoxy-s-triazin-2-yl]amine
  • N'-(1,3-benzothiazol-6-yl)-6-methoxy-N-(2-phenylpropan-2-yl)-1,3,5-triazine-2,4-diamine
  • N'-(1,3-benzothiazol-6-yl)-6-methoxy-N-(1-methyl-1-phenyl-ethyl)-1,3,5-triazine-2,4-diamine
  • N'-(1,3-benzothiazol-6-yl)-6-methoxy-N-(1-methyl-1-phenylethyl)-1,3,5-triazine-2,4-diamine
  • [4-(1,3-benzothiazol-6-ylamino)-6-methoxy-s-triazin-2-yl]-(1-methyl-1-phenyl-ethyl)amine

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens kinase insert domain receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Onchocerca volvulus Get druggable targets OG5_130320 All targets in OG5_130320
Brugia malayi Immunoglobulin I-set domain containing protein Get druggable targets OG5_130320 All targets in OG5_130320
Onchocerca volvulus Tyrosine kinase homolog Get druggable targets OG5_130320 All targets in OG5_130320
Loa Loa (eye worm) TK/KIN16 protein kinase Get druggable targets OG5_130320 All targets in OG5_130320
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax unspecified product 0.013 0.1718 0.137
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0222 0.3068 0.4574
Onchocerca volvulus Cathepsin L homolog 0.0376 0.5353 1
Brugia malayi Papain family cysteine protease containing protein 0.0222 0.3068 0.2175
Entamoeba histolytica cysteine protease, putative 0.0376 0.5353 1
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0376 0.5353 1
Trypanosoma cruzi cysteine peptidase, putative 0.0376 0.5353 0.4755
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0376 0.5353 0.5353
Loa Loa (eye worm) hypothetical protein 0.0246 0.3427 0.3419
Entamoeba histolytica cysteine protease, putative 0.0222 0.3068 0.4574
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.013 0.1718 0.0651
Brugia malayi cathepsin F-like cysteine proteinase 0.013 0.1718 0.0651
Toxoplasma gondii cathepsin CPL 0.0376 0.5353 1
Echinococcus granulosus cathepsin b 0.0691 1 1
Echinococcus granulosus cathepsin l cysteine peptidase 0.0376 0.5353 0.5353
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0691 1 1
Leishmania major cathepsin L-like protease 0.0376 0.5353 1
Schistosoma mansoni cathepsin F (C01 family) 0.0246 0.3427 0.3427
Entamoeba histolytica cysteine protease, putative 0.0222 0.3068 0.4574
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0091 0.1141 0.1131
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0376 0.5353 1
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0091 0.1141 0.1141
Loa Loa (eye worm) hypothetical protein 0.0018 0.0054 0.0042
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0091 0.1141 0.1141
Plasmodium falciparum cysteine proteinase falcipain 3 0.0376 0.5353 1
Leishmania major cathepsin L-like protease 0.0376 0.5353 1
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0091 0.1141 0.1141
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0376 0.5353 1
Echinococcus multilocularis cathepsin L 0.0091 0.1141 0.1141
Brugia malayi Cathepsin L-like precursor 0.0246 0.3427 0.258
Trypanosoma cruzi cruzipain precursor, putative 0.013 0.1718 0.0651
Entamoeba histolytica cysteine protease, putative 0.0222 0.3068 0.4574
Plasmodium vivax unspecified product 0.0222 0.3068 0.4574
Echinococcus granulosus cathepsin l1 0.0376 0.5353 0.5353
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0376 0.5353 1
Echinococcus multilocularis cysteine protease 0.0376 0.5353 0.5353
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0376 0.5353 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0376 0.5353 1
Brugia malayi Cathepsin L-like cysteine proteinase 0.0246 0.3427 0.258
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0183 0.249 0.2481
Entamoeba histolytica cysteine proteinase, putative 0.0376 0.5353 1
Leishmania major cysteine peptidase A (CPA) 0.0376 0.5353 1
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0091 0.1141 0.1141
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0376 0.5353 1
Echinococcus granulosus roundabout 2 0.0018 0.0054 0.0054
Echinococcus multilocularis cathepsin L 0.0222 0.3068 0.3068
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0015 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0091 0.1141 0.1131
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0091 0.1141 0.1141
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0091 0.1141 0.1131
Loa Loa (eye worm) hypothetical protein 0.013 0.1718 0.1708
Loa Loa (eye worm) cysteine protease 0.0376 0.5353 0.5348
Brugia malayi Cathepsin L-like precursor 0.013 0.1718 0.0651
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0376 0.5353 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0376 0.5353 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0376 0.5353 1
Entamoeba histolytica cysteine protease, putative 0.0222 0.3068 0.4574
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0376 0.5353 1
Loa Loa (eye worm) hypothetical protein 0.0091 0.1141 0.1131
Entamoeba histolytica cysteine protease, putative 0.0222 0.3068 0.4574
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0376 0.5353 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0376 0.5353 1
Plasmodium vivax vivapain-2 0.0376 0.5353 1
Echinococcus multilocularis cysteine protease 0.0376 0.5353 0.5353
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0376 0.5353 1
Schistosoma mansoni cathepsin s 0.013 0.1718 0.1718
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0376 0.5353 0.5353
Entamoeba histolytica cysteine proteinase, putative 0.0222 0.3068 0.4574
Onchocerca volvulus 0.0376 0.5353 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0091 0.1141 0.1141
Echinococcus multilocularis cathepsin L cysteine protease 0.0376 0.5353 0.5353
Plasmodium vivax vivapain-1 0.0222 0.3068 0.4574
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0277 0.3881 0.6505
Echinococcus granulosus cathepsin b 0.0691 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0376 0.5353 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0376 0.5353 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0376 0.5353 1
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0246 0.3427 0.258
Echinococcus multilocularis roundabout 2 0.0018 0.0054 0.0054
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0376 0.5353 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0376 0.5353 1
Schistosoma mansoni cathepsin F (C01 family) 0.0376 0.5353 0.5353
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0376 0.5353 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0091 0.1141 0.1141
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0222 0.3068 0.3068
Entamoeba histolytica cysteine protease, putative 0.0222 0.3068 0.4574
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0376 0.5353 1
Onchocerca volvulus 0.0376 0.5353 1
Echinococcus granulosus cathepsin L cysteine protease 0.0222 0.3068 0.3068
Schistosoma mansoni cathepsin C 0.0091 0.1141 0.1141
Trypanosoma cruzi cysteine proteinase, putative 0.0222 0.3068 0.2175
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0222 0.3068 0.2175
Entamoeba histolytica cysteine protease, putative 0.0222 0.3068 0.4574
Loa Loa (eye worm) fibroinase 0.0376 0.5353 0.5348
Brugia malayi Cathepsin L-like precursor 0.0376 0.5353 0.4755
Loa Loa (eye worm) hypothetical protein 0.0018 0.0054 0.0042
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0691 1 1
Loa Loa (eye worm) hypothetical protein 0.0091 0.1141 0.1131
Echinococcus multilocularis cathepsin b 0.0691 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0376 0.5353 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0376 0.5353 0.5353
Entamoeba histolytica cysteine proteinase, putative 0.0246 0.3427 0.5426
Schistosoma mansoni cell adhesion molecule 0.0015 0.0012 0.0012
Brugia malayi Papain family cysteine protease containing protein 0.0376 0.5353 0.4755
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0376 0.5353 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0222 0.3068 0.3068
Plasmodium falciparum cysteine proteinase falcipain 1 0.0222 0.3068 0.4574
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0691 1 1
Echinococcus granulosus cathepsin L 0.0222 0.3068 0.3068
Entamoeba histolytica cysteine proteinase 2 0.0222 0.3068 0.4574
Trypanosoma cruzi cruzipain precursor, putative 0.0376 0.5353 0.4755
Loa Loa (eye worm) papain family cysteine protease containing protein 0.013 0.1718 0.1708
Echinococcus granulosus cathepsin L 0.0091 0.1141 0.1141
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0091 0.1141 0.1141
Onchocerca volvulus Cathepsin F homolog 0.0376 0.5353 1
Echinococcus multilocularis cathepsin b 0.0691 1 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0376 0.5353 1
Entamoeba histolytica cysteine protease, putative 0.0222 0.3068 0.4574
Entamoeba histolytica cysteine protease, putative 0.0222 0.3068 0.4574
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0376 0.5353 1
Brugia malayi Cathepsin L-like precursor 0.0376 0.5353 0.4755
Leishmania major cathepsin L-like protease 0.0376 0.5353 1
Brugia malayi Cathepsin L-like precursor 0.0376 0.5353 0.4755
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0376 0.5353 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0376 0.5353 1
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0277 0.3881 0.3093
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0246 0.3427 0.5426
Trypanosoma cruzi cysteine peptidase, putative 0.0376 0.5353 0.4755
Entamoeba histolytica cysteine proteinase, putative 0.0222 0.3068 0.4574
Loa Loa (eye worm) hypothetical protein 0.0091 0.1141 0.1131
Schistosoma mansoni cathepsin F (C01 family) 0.0376 0.5353 0.5353
Brugia malayi Immunoglobulin I-set domain containing protein 0.0183 0.249 0.1523
Giardia lamblia Cathepsin B precursor 0.0277 0.3881 1
Loa Loa (eye worm) hypothetical protein 0.0376 0.5353 0.5348
Entamoeba histolytica cysteine proteinase 1, putative 0.0222 0.3068 0.4574
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0376 0.5353 1
Onchocerca volvulus 0.0376 0.5353 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0376 0.5353 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0376 0.5353 1
Trypanosoma cruzi cysteine peptidase, putative 0.0222 0.3068 0.2175
Onchocerca volvulus Cathepsin L homolog 0.0376 0.5353 1
Schistosoma mansoni cathepsin B (C01 family) 0.0091 0.1141 0.1141
Brugia malayi Cathepsin L-like precursor 0.0246 0.3427 0.258
Onchocerca volvulus 0.0376 0.5353 1
Giardia lamblia Cathepsin B precursor 0.0277 0.3881 1
Onchocerca volvulus 0.0376 0.5353 1
Onchocerca volvulus Tyrosine kinase homolog 0.0171 0.2312 0.278
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0376 0.5353 1
Loa Loa (eye worm) hypothetical protein 0.0691 1 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0691 1 1
Plasmodium vivax vivapain-2 0.0376 0.5353 1
Leishmania major cathepsin L-like protease 0.0376 0.5353 1
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0091 0.1141 0.1131
Brugia malayi cathepsin L-like precursor 0.0246 0.3427 0.258
Loa Loa (eye worm) hypothetical protein 0.0246 0.3427 0.3419
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0376 0.5353 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0376 0.5353 0.5348
Plasmodium vivax vivapain-3 0.0222 0.3068 0.4574
Brugia malayi Cathepsin L-like precursor 0.0376 0.5353 0.4755
Schistosoma mansoni cathepsin S (C01 family) 0.0091 0.1141 0.1141
Onchocerca volvulus 0.0376 0.5353 1
Trypanosoma brucei cysteine peptidase C (CPC) 0.0277 0.3881 0.3558
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0246 0.3427 0.5426
Loa Loa (eye worm) hypothetical protein 0.013 0.1718 0.1708
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0091 0.1141 0.1141
Onchocerca volvulus 0.0246 0.3427 0.5426
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0222 0.3068 0.4574
Trypanosoma cruzi cysteine peptidase, putative 0.0376 0.5353 0.4755
Brugia malayi Cathepsin L-like precursor 0.0376 0.5353 0.4755
Onchocerca volvulus 0.0167 0.2255 0.2644
Loa Loa (eye worm) hypothetical protein 0.0091 0.1141 0.1131
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0277 0.3881 0.3881
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0376 0.5353 1
Trypanosoma cruzi cysteine protease, putative 0.0222 0.3068 0.2175
Loa Loa (eye worm) cathepsin B 0.0277 0.3881 0.3874
Entamoeba histolytica cysteine protease, putative 0.0222 0.3068 0.4574
Leishmania major cathepsin L-like protease 0.0376 0.5353 1
Brugia malayi Papain family cysteine protease containing protein 0.0222 0.3068 0.2175
Trypanosoma cruzi cysteine proteinase, putative 0.0222 0.3068 0.2175
Entamoeba histolytica cysteine proteinase, putative 0.0222 0.3068 0.4574
Leishmania major cathepsin L-like protease 0.0376 0.5353 1
Toxoplasma gondii cathepsin B 0.0277 0.3881 0.6505
Leishmania major cathepsin L-like protease 0.0376 0.5353 1
Trypanosoma cruzi cysteine peptidase, putative 0.013 0.1718 0.0651
Brugia malayi Cathepsin L-like precursor 0.0376 0.5353 0.4755
Loa Loa (eye worm) hypothetical protein 0.013 0.1718 0.1708
Trypanosoma cruzi cysteine peptidase, putative 0.0376 0.5353 0.4755
Entamoeba histolytica cysteine protease, putative 0.0222 0.3068 0.4574
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0376 0.5353 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0376 0.5353 1
Leishmania major cathepsin L-like protease 0.0376 0.5353 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0376 0.5353 1
Loa Loa (eye worm) hypothetical protein 0.0246 0.3427 0.3419
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0222 0.3068 0.3068
Onchocerca volvulus 0.0376 0.5353 1
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0691 1 1
Entamoeba histolytica cysteine protease, putative 0.0222 0.3068 0.4574
Entamoeba histolytica cysteine proteinase, putative 0.0376 0.5353 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0376 0.5353 1
Entamoeba histolytica cysteine proteinase, putative 0.0222 0.3068 0.4574
Echinococcus granulosus cathepsin l1 0.0246 0.3427 0.3427
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0376 0.5353 0.5348
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0376 0.5353 1
Giardia lamblia Cathepsin B precursor 0.0277 0.3881 1
Echinococcus granulosus cathepsin L cysteine proteinase 0.0376 0.5353 0.5353
Loa Loa (eye worm) hypothetical protein 0.0091 0.1141 0.1131
Loa Loa (eye worm) ctsf protein 0.0376 0.5353 0.5348
Entamoeba histolytica cysteine protease, putative 0.0222 0.3068 0.4574
Echinococcus granulosus cysteine protease 0.0222 0.3068 0.3068

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) uM Inhibition of mouse Fibroblast growth factor receptor 1 expressed in NIH 3T3 fibroblasts; Not measured ChEMBL. 15771417
IC50 (binding) uM Inhibition of human Epidermal growth factor receptor expressed in A431; Not measured ChEMBL. 15771417
IC50 (binding) uM Inhibition of human Insulin receptor expressed in CHO-cells; Not measured ChEMBL. 15771417
IC50 (binding) 0 uM Inhibition of human Insulin receptor expressed in CHO-cells; Not measured ChEMBL. 15771417
IC50 (binding) 0 uM Inhibition of mouse Fibroblast growth factor receptor 1 expressed in NIH 3T3 fibroblasts; Not measured ChEMBL. 15771417
IC50 (binding) 0 uM Inhibition of human Epidermal growth factor receptor expressed in A431; Not measured ChEMBL. 15771417
IC50 (binding) = 6.1 uM In vitro inhibition of Vascular endothelial growth factor receptor 2 at 10 uM ATP ChEMBL. 15771417
IC50 (binding) = 6.1 uM In vitro inhibition of Vascular endothelial growth factor receptor 2 at 10 uM ATP ChEMBL. 15771417
IC50 (functional) > 30 uM Inhibition of KDR-induced MAP kinase autophosphorylation assay in HUVEC cells ChEMBL. 15771417
IC50 (functional) > 30 uM Inhibition of KDR-induced MAP kinase autophosphorylation assay in HUVEC cells ChEMBL. 15771417

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.