Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0 | 0.5 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0397 | 1 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | trans-2-enoyl-ACP reductase, FabK | 0.0397 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0 | 0.5 |
Mycobacterium tuberculosis | Possible alanine rich oxidoreductase | 0.0397 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0 | 0.5 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0 | 0.5 |
Trichomonas vaginalis | 2-nitropropane dioxygenase precursor, putative | 0.0397 | 1 | 0.5 |
Brugia malayi | hypothetical protein | 0.0036 | 0 | 0.5 |
Mycobacterium ulcerans | 2-nitropropane dioxygenase | 0.0397 | 1 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0397 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | > 100 uM | Inhibitory concentration against interleukin-2 binding | ChEMBL. | 15686897 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.