Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | 0 ug ml-1 | Minimum inhibitory concentration against Staphylococcus aureus (strain A15090) in presence of 50% calf serum; Not determined | ChEMBL. | 15324898 |
MIC (functional) | 0 ug ml-1 | Minimum inhibitory concentration against methicillin resistant Staphylococcus aureus (strain A27223) in presence of 50% calf serum; Not determined | ChEMBL. | 15324898 |
MIC (functional) | 0 ug ml-1 | Minimum inhibitory concentration against Enterococcus faecalis (strain A20688) in presence of 50% calf serum; Not determined | ChEMBL. | 15324898 |
MIC (functional) | = 4 ug ml-1 | Minimum inhibitory concentration against methicillin resistant Staphylococcus aureus (strain A27223) in absence of calf serum | ChEMBL. | 15324898 |
MIC (functional) | = 8 ug ml-1 | Minimum inhibitory concentration against Staphylococcus aureus (strain A15090) in absence of calf serum | ChEMBL. | 15324898 |
MIC (functional) | = 16 ug ml-1 | Minimum inhibitory concentration against Enterococcus faecalis (strain A20688) in absence of calf serum | ChEMBL. | 15324898 |
MIC (functional) | > 64 ug ml-1 | Minimum inhibitory concentration against Haemophilus influenzae (strain A20191) in absence of calf serum | ChEMBL. | 15324898 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.