Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0715 | 0.2531 | 0.2531 |
Onchocerca volvulus | 0.0121 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.2469 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0715 | 0.2531 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0715 | 0.2531 | 0.2531 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0715 | 0.2531 | 0.2531 |
Onchocerca volvulus | 0.0121 | 0 | 0.5 | |
Loa Loa (eye worm) | carboxylesterase | 0.0715 | 0.2531 | 0.2531 |
Echinococcus multilocularis | acetylcholinesterase | 0.0715 | 0.2531 | 0.2531 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0121 | 0 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0121 | 0 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0715 | 0.2531 | 0.2531 |
Schistosoma mansoni | hormone-sensitive lipase (S09 family) | 0.2469 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0715 | 0.2531 | 0.2531 |
Echinococcus multilocularis | hormone sensitive lipase | 0.2469 | 1 | 1 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0121 | 0 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0715 | 0.2531 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0715 | 0.2531 | 0.2531 |
Onchocerca volvulus | 0.0121 | 0 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0715 | 0.2531 | 0.2531 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0121 | 0 | 0.5 |
Onchocerca volvulus | 0.0121 | 0 | 0.5 | |
Schistosoma mansoni | hormone-sensitive lipase (S09 family) | 0.2469 | 1 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0121 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0715 | 0.2531 | 0.2531 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0121 | 0 | 0.5 |
Schistosoma mansoni | hormone-sensitive lipase (S09 family) | 0.2469 | 1 | 1 |
Onchocerca volvulus | 0.0121 | 0 | 0.5 | |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0715 | 0.2531 | 0.2531 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.