TDR Targets

Basic information

Technical information

TDR Targets ID: 328954
Name: 3-[[6-chloro-5-[6-(3-chloroanilino)pyrazin-2- yl]pyridin-3-yl]amino]propan-1-ol
MW: 390.266 | Formula: C18H17Cl2N5O
H donors: 3 H acceptors: 4 LogP: 4.05 Rotable bonds: 7
Rule of 5 violations (Lipinski): 1
SMILES: OCCCNc1cnc(c(c1)c1cncc(n1)Nc1cccc(c1)Cl)Cl
InChi: 1S/C18H17Cl2N5O/c19-12-3-1-4-13(7-12)24-17-11-21-10-16(25-17)15-8-14(9-23-18(15)20)22-5-2-6-26/h1,3-4,7-11,22,26H,2,5-6H2,(H,24,25)
InChiKey: CWSMCLMKHVQLFW-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

3-[[6-chloro-5-[6-(3-chloroanilino)pyrazin-2-yl]-3-pyridyl]amino]propan-1-ol
3-[[6-chloro-5-[6-(3-chloroanilino)-2-pyrazinyl]-3-pyridyl]amino]-1-propanol
3-[[6-chloro-5-[6-[(3-chlorophenyl)amino]pyrazin-2-yl]pyridin-3-yl]amino]propan-1-ol
3-[[6-chloro-5-[6-[(3-chlorophenyl)amino]pyrazin-2-yl]-3-pyridyl]amino]propan-1-ol
3-[[6-chloro-5-[6-[(3-chlorophenyl)amino]-2-pyrazinyl]-3-pyridyl]amino]propan-1-ol
Pyrazine-Pyridine Biheteroaryl 76

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Homo sapiens	kinase insert domain receptor	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Onchocerca volvulus	Tyrosine kinase homolog	Get druggable targets OG5_130320	All targets in OG5_130320
Loa Loa (eye worm)	TK/KIN16 protein kinase	Get druggable targets OG5_130320	All targets in OG5_130320
Onchocerca volvulus		Get druggable targets OG5_130320	All targets in OG5_130320
Brugia malayi	Immunoglobulin I-set domain containing protein	Get druggable targets OG5_130320	All targets in OG5_130320

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0615	0.3076	0.8152
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0344	0.1689	0.3305
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0159	0.0742	0.0742
Trypanosoma cruzi	cysteine peptidase, putative	0.0615	0.3076	0.2521
Echinococcus multilocularis	cysteine protease	0.0615	0.3076	0.3076
Trypanosoma cruzi	cysteine protease, putative	0.0344	0.1689	0.1022
Entamoeba histolytica	cysteine proteinase, putative	0.043	0.213	0.5946
Onchocerca volvulus	Cathepsin L homolog	0.0615	0.3076	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0615	0.3076	0.8152
Loa Loa (eye worm)	hypothetical protein	0.0159	0.0742	0.0739
Entamoeba histolytica	cysteine protease, putative	0.0344	0.1689	0.4054
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0615	0.3076	0.8152
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.1968	1	1
Trypanosoma cruzi	cysteine peptidase, putative	0.0615	0.3076	0.2521
Schistosoma mansoni	cathepsin S (C01 family)	0.0159	0.0742	0.0742
Brugia malayi	cathepsin L-like cysteine proteinase, identical	0.0185	0.0874	0.0142
Echinococcus granulosus	cathepsin L	0.0344	0.1689	0.1689
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0615	0.3076	0.724
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.1968	1	1
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0159	0.0742	0.0739
Schistosoma mansoni	cathepsin B (C01 family)	0.0159	0.0742	0.0742
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0159	0.0742	0.0739
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0615	0.3076	0.8152
Echinococcus granulosus	neurotracting:lsamp:neurotrimin:obcam	0.0015	0.0004	0.0004
Brugia malayi	Cathepsin L-like precursor	0.0615	0.3076	0.2521
Onchocerca volvulus	Cathepsin F homolog	0.0615	0.3076	1
Trypanosoma cruzi	cysteine peptidase, putative	0.0615	0.3076	0.2521
Echinococcus multilocularis	cathepsin L cysteine protease	0.0615	0.3076	0.3076
Entamoeba histolytica	cysteine protease, putative	0.0344	0.1689	0.4054
Plasmodium vivax	vivapain-1	0.0344	0.1689	0.4054
Echinococcus granulosus	cathepsin L	0.0159	0.0742	0.0742
Loa Loa (eye worm)	hypothetical protein	0.043	0.213	0.2127
Loa Loa (eye worm)	hypothetical protein	0.0185	0.0874	0.087
Plasmodium vivax	vivapain-3	0.0344	0.1689	0.4054
Onchocerca volvulus		0.0615	0.3076	1
Giardia lamblia	Cathepsin B precursor	0.0719	0.3606	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0719	0.3606	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0615	0.3076	0.724
Loa Loa (eye worm)	hypothetical protein	0.0159	0.0742	0.0739
Plasmodium falciparum	cysteine proteinase falcipain 2b	0.0615	0.3076	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0615	0.3076	0.8152
Schistosoma mansoni	cell adhesion molecule	0.0015	0.0004	0.0004
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0344	0.1689	0.1689
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.0719	0.3606	0.3093
Echinococcus granulosus	roundabout 2	0.0018	0.0019	0.0019
Onchocerca volvulus		0.0167	0.0781	0.0165
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0615	0.3076	0.8152
Entamoeba histolytica	cysteine protease, putative	0.0344	0.1689	0.4054
Giardia lamblia	Cathepsin B precursor	0.0719	0.3606	1
Loa Loa (eye worm)	cathepsin B	0.0719	0.3606	0.3603
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0159	0.0742	0.0742
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0615	0.3076	0.8152
Entamoeba histolytica	cysteine protease, putative	0.0344	0.1689	0.4054
Echinococcus multilocularis	cathepsin L	0.0159	0.0742	0.0742
Toxoplasma gondii	cathepsin CPL	0.0615	0.3076	0.8152
Onchocerca volvulus		0.0615	0.3076	1
Echinococcus granulosus	cathepsin l1	0.0615	0.3076	0.3076
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0615	0.3076	0.724
Schistosoma mansoni	cathepsin F (C01 family)	0.0615	0.3076	0.3076
Entamoeba histolytica	cysteine protease, putative	0.0344	0.1689	0.4054
Onchocerca volvulus	Cathepsin L homolog	0.0615	0.3076	1
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0183	0.0862	0.013
Loa Loa (eye worm)	ctsf protein	0.0615	0.3076	0.3074
Echinococcus granulosus	cathepsin l cysteine peptidase	0.0615	0.3076	0.3076
Loa Loa (eye worm)	hypothetical protein	0.0159	0.0742	0.0739
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0615	0.3076	0.8152
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0615	0.3076	0.724
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.1968	1	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0615	0.3076	0.724
Entamoeba histolytica	cysteine proteinase 1, putative	0.0344	0.1689	0.4054
Onchocerca volvulus		0.0615	0.3076	1
Onchocerca volvulus		0.0615	0.3076	1
Giardia lamblia	Cathepsin B precursor	0.0719	0.3606	1
Loa Loa (eye worm)	fibroinase	0.0615	0.3076	0.3074
Trypanosoma cruzi	cysteine peptidase, putative	0.0615	0.3076	0.2521
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0615	0.3076	0.3074
Trypanosoma cruzi	cysteine peptidase (N-terminal), putative	0.0344	0.1689	0.1022
Loa Loa (eye worm)	Papain cysteine protease/cathepsin propeptide inhibitor-containing protein	0.0615	0.3076	0.3074
Trypanosoma cruzi	cruzipain precursor, putative	0.0185	0.0874	0.0142
Entamoeba histolytica	cysteine proteinase 2	0.0344	0.1689	0.4054
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.0159	0.0742	0.0742
Entamoeba histolytica	cysteine protease, putative	0.0344	0.1689	0.4054
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0344	0.1689	0.3305
Loa Loa (eye worm)	hypothetical protein	0.0159	0.0742	0.0739
Loa Loa (eye worm)	hypothetical protein	0.0185	0.0874	0.087
Echinococcus multilocularis	cathepsin L cysteine protease	0.0615	0.3076	0.3076
Plasmodium vivax	vivapain-2	0.0615	0.3076	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0615	0.3076	0.8152
Entamoeba histolytica	cysteine protease, putative	0.0344	0.1689	0.4054
Echinococcus granulosus	cathepsin b	0.1968	1	1
Schistosoma mansoni	cathepsin F (C01 family)	0.0615	0.3076	0.3076
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0615	0.3076	0.8152
Schistosoma mansoni	SmCB2 peptidase (C01 family)	0.1968	1	1
Echinococcus multilocularis	roundabout 2	0.0018	0.0019	0.0019
Toxoplasma gondii	cathepsin B	0.0719	0.3606	1
Brugia malayi	Cathepsin L-like precursor	0.0615	0.3076	0.2521
Trypanosoma cruzi	cysteine proteinase, putative	0.0344	0.1689	0.1022
Entamoeba histolytica	cysteine proteinase, putative	0.0344	0.1689	0.4054
Echinococcus granulosus	cathepsin b	0.1968	1	1
Entamoeba histolytica	cysteine protease, putative	0.0344	0.1689	0.4054
Echinococcus multilocularis	cysteine protease	0.0615	0.3076	0.3076
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0344	0.1689	0.1689
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.0344	0.1689	0.1689
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0615	0.3076	0.724
Echinococcus multilocularis	cathepsin b	0.1968	1	1
Onchocerca volvulus	Tyrosine kinase homolog	0.0171	0.0801	0.025
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0019	0.0015
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.0615	0.3076	0.8152
Loa Loa (eye worm)	hypothetical protein	0.0159	0.0742	0.0739
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0615	0.3076	0.724
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0615	0.3076	0.724
Leishmania major	cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like	0.0719	0.3606	1
Trypanosoma cruzi	cysteine peptidase, putative	0.0185	0.0874	0.0142
Plasmodium vivax	unspecified product	0.0344	0.1689	0.4054
Brugia malayi	Cathepsin L-like precursor	0.0615	0.3076	0.2521
Plasmodium falciparum	cysteine proteinase falcipain 3	0.0615	0.3076	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0615	0.3076	0.8152
Entamoeba histolytica	cysteine protease, putative	0.0344	0.1689	0.4054
Plasmodium falciparum	cysteine proteinase falcipain 1	0.0344	0.1689	0.4054
Brugia malayi	Cathepsin L-like precursor	0.043	0.213	0.1499
Onchocerca volvulus		0.0615	0.3076	1
Loa Loa (eye worm)	hypothetical protein	0.0185	0.0874	0.087
Loa Loa (eye worm)	hypothetical protein	0.0159	0.0742	0.0739
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0615	0.3076	0.3076
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0615	0.3076	0.8152
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.043	0.213	0.4847
Entamoeba histolytica	cysteine proteinase, putative	0.0344	0.1689	0.4054
Onchocerca volvulus		0.0615	0.3076	1
Entamoeba histolytica	cysteine proteinase, putative	0.0615	0.3076	1
Schistosoma mansoni	cathepsin s	0.0185	0.0874	0.0874
Loa Loa (eye worm)	hypothetical protein	0.0615	0.3076	0.3074
Echinococcus granulosus	cathepsin L cysteine proteinase	0.0615	0.3076	0.3076
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0615	0.3076	0.8152
Trypanosoma cruzi	cysteine proteinase, putative	0.0344	0.1689	0.1022
Schistosoma mansoni	cathepsin C	0.0159	0.0742	0.0742
Brugia malayi	Cathepsin L-like precursor	0.0185	0.0874	0.0142
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0719	0.3606	0.3606
Entamoeba histolytica	cysteine proteinase, putative	0.0615	0.3076	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.043	0.213	0.4847
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0615	0.3076	0.8152
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0615	0.3076	0.8152
Trypanosoma cruzi	cruzipain precursor, putative	0.0615	0.3076	0.2521
Loa Loa (eye worm)	hypothetical protein	0.1968	1	1
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.1968	1	1
Loa Loa (eye worm)	cysteine proteinase cathepsin Z	0.0159	0.0742	0.0739
Trypanosoma cruzi	cysteine peptidase, clan CA, family C1, cathepsin L-like, putative	0.043	0.213	0.1499
Loa Loa (eye worm)	hypothetical protein	0.043	0.213	0.2127
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0615	0.3076	0.8152
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0615	0.3076	0.724
Entamoeba histolytica	cysteine protease, putative	0.0344	0.1689	0.4054
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.0159	0.0742	0.0742
Brugia malayi	Papain family cysteine protease containing protein	0.0344	0.1689	0.1022
Schistosoma mansoni	cathepsin F (C01 family)	0.043	0.213	0.213
Schistosoma mansoni	subfamily C1A non-peptidase homologue (C01 family)	0.0159	0.0742	0.0742
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0159	0.0742	0.0742
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.0615	0.3076	0.3076
Brugia malayi	Cathepsin L-like precursor	0.0615	0.3076	0.2521
Entamoeba histolytica	cysteine protease, putative	0.0344	0.1689	0.4054
Loa Loa (eye worm)	hypothetical protein	0.043	0.213	0.2127
Trypanosoma cruzi	cysteine peptidase, putative	0.0344	0.1689	0.1022
Trypanosoma brucei	cysteine peptidase C (CPC)	0.0719	0.3606	1
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0159	0.0742	0.0742
Onchocerca volvulus		0.043	0.213	0.5946
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.0183	0.0862	0.0859
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0615	0.3076	0.8152
Plasmodium vivax	vivapain-2	0.0615	0.3076	1
Echinococcus granulosus	cathepsin L cysteine protease	0.0344	0.1689	0.1689
Brugia malayi	Papain family cysteine protease containing protein	0.0344	0.1689	0.1022
Plasmodium vivax	unspecified product	0.0185	0.0874	0.0564
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0615	0.3076	0.8152
Brugia malayi	Cathepsin L-like cysteine proteinase	0.043	0.213	0.1499
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0615	0.3076	0.724
Brugia malayi	cathepsin F-like cysteine proteinase	0.0185	0.0874	0.0142
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0615	0.3076	0.8152
Brugia malayi	Cathepsin L-like precursor	0.043	0.213	0.1499
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0159	0.0742	0.0742
Brugia malayi	Cathepsin L-like precursor	0.0615	0.3076	0.2521
Brugia malayi	Papain family cysteine protease containing protein	0.0615	0.3076	0.2521
Schistosoma mansoni	dipeptidyl-peptidase I (C01 family)	0.0159	0.0742	0.0742
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.0615	0.3076	0.724
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0615	0.3076	0.8152
Brugia malayi	Cathepsin L-like precursor	0.0615	0.3076	0.2521
Onchocerca volvulus		0.0615	0.3076	1
Entamoeba histolytica	cysteine protease, putative	0.0344	0.1689	0.4054
Entamoeba histolytica	cysteine protease, putative	0.0615	0.3076	1
Entamoeba histolytica	cysteine protease, putative	0.0344	0.1689	0.4054
Echinococcus granulosus	cathepsin l1	0.043	0.213	0.213
Plasmodium falciparum	cysteine proteinase falcipain 2a	0.0615	0.3076	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0615	0.3076	0.8152
Echinococcus granulosus	cysteine protease	0.0344	0.1689	0.1689
Echinococcus multilocularis	cathepsin b	0.1968	1	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0615	0.3076	0.8152
Echinococcus multilocularis	cathepsin L	0.0344	0.1689	0.1689
Entamoeba histolytica	cysteine proteinase, putative	0.0344	0.1689	0.4054
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0019	0.0015
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0615	0.3076	0.8152
Brugia malayi	cathepsin L-like precursor	0.043	0.213	0.1499
Loa Loa (eye worm)	cysteine protease	0.0615	0.3076	0.3074
Entamoeba histolytica	cysteine proteinase, putative	0.0344	0.1689	0.4054
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0185	0.0874	0.087
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0615	0.3076	0.8152

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	> 10 uM	Inhibition of cyclin-dependent kinase 1 activity	ChEMBL.	16033269
IC50 (binding)	> 10 uM	Inhibition of vascular endothelial growth factor receptor 2	ChEMBL.	16033269
IC50 (binding)	> 10 uM	Inhibition of vascular endothelial growth factor receptor 2	ChEMBL.	16033269

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL188904
PubChem: 5330395

Bibliographic References

1 literature reference was collected for this gene.

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Detailed information for compound 328954