Detailed information for compound 329286

Basic information

Technical information
  • TDR Targets ID: 329286
  • Name: 9-[(2,6-difluorophenyl)methyl]-6-[(4-nitrophe nyl)methylsulfanyl]purine
  • MW: 413.401 | Formula: C19H13F2N5O2S
  • H donors: 0 H acceptors: 5 LogP: 4.02 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1cccc(c1Cn1cnc2c1ncnc2SCc1ccc(cc1)[N+](=O)[O-])F
  • InChi: 1S/C19H13F2N5O2S/c20-15-2-1-3-16(21)14(15)8-25-11-24-17-18(25)22-10-23-19(17)29-9-12-4-6-13(7-5-12)26(27)28/h1-7,10-11H,8-9H2
  • InChiKey: IOCMQPPYRHAXCY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 9-[(2,6-difluorophenyl)methyl]-6-[(4-nitrophenyl)methylthio]purine
  • 9-(2,6-difluorobenzyl)-6-[(4-nitrobenzyl)thio]purine

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi exodeoxyribonuclease III family protein 0.0036 0.0453 0.0478
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0589 0.1743
Echinococcus multilocularis JmjC domain containing protein 4 0.0015 0.0134 0.0119
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0023 0.0263 0.027
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0037 0.0469 0.0495
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.0061 0.0837 0.4485
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0018 0.0183 0.3827
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0018 0.0183 0.3827
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0055 0.0744 0.073
Loa Loa (eye worm) hypothetical protein 0.0009 0.0049 0.0036
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0037 0.0469 0.0455
Brugia malayi cathepsin L precursor 0.0018 0.0183 0.0183
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0183 0.0542
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0183 0.0568
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0183 0.1318
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0183 0.0183
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0183 0.0168
Echinococcus granulosus serine:threonine protein kinase PLK1 0.009 0.1287 0.1273
Leishmania major hypothetical protein, conserved 0.0015 0.0134 0.0402
Schistosoma mansoni DNA helicase recq1 0.0027 0.0324 0.0309
Brugia malayi jmjC domain containing protein 0.0015 0.0134 0.0129
Echinococcus multilocularis replication factor c subunit 1 0.0009 0.0049 0.0033
Schistosoma mansoni hypothetical protein 0.0323 0.4848 0.484
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0008 0.0025 0.001
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0007 0.0016 0.0046
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0036 0.0453 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0469 0.1538
Leishmania major DNA polymerase eta, putative 0.0061 0.0842 0.2801
Brugia malayi hypothetical protein 0.0019 0.0193 0.0194
Plasmodium vivax vivapain-2 0.0018 0.0183 0.3827
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.003 0.0362 0.1172
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0038 0.0489 0.0475
Brugia malayi cathepsin L-like cysteine proteinase 0.0018 0.0183 0.0183
Schistosoma mansoni jumonji domain containing protein 0.0015 0.0134 0.0119
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0015 0.0134 0.0402
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.02 0.2959 0.3211
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0036 0.0453 0.1482
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0183 0.0183
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0018 0.0183 0.0168
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.00000000017268 0.00000000051101
Loa Loa (eye worm) hypothetical protein 0.0018 0.0183 0.0183
Trypanosoma cruzi polo-like protein kinase, putative 0.009 0.1287 0.1387
Giardia lamblia Cathepsin B precursor 0.02 0.2966 1
Toxoplasma gondii peptidylprolyl isomerase 0.0031 0.0379 0.1232
Trypanosoma cruzi polo-like protein kinase, putative 0.009 0.1287 0.1387
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0193 0.0178
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.00000000017268 0.00000000051101
Loa Loa (eye worm) hypothetical protein 0.0011 0.0071 0.0061
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0032 0.0396 0.2991
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0069 0.0954 0.094
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0606 0.9182 0.918
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0183 0.0183
Schistosoma mansoni DNA helicase recq5 0.0027 0.0324 0.0309
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0029 0.0344 0.375
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0193 0.0178
Schistosoma mansoni cpg binding protein 0.0029 0.0349 0.0334
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0193 0.0178
Brugia malayi jmjC domain containing protein 0.0058 0.0789 0.0844
Loa Loa (eye worm) hypothetical protein 0.0018 0.0183 0.0183
Entamoeba histolytica cysteine protease, putative 0.0018 0.0183 0.1318
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0183 0.0168
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0351 0.0336
Onchocerca volvulus 0.0018 0.0183 0.0498
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0009 0.0049 0.0145
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0183 0.0542
Trypanosoma cruzi DNA damage repair protein, putative 0.0011 0.008 0.007
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.0183 0.0183
Schistosoma mansoni jumonji/arid domain-containing protein 0.0058 0.0789 0.0775
Echinococcus multilocularis phd:f box containing protein 0.0015 0.0134 0.0119
Giardia lamblia Cysteine protease 0.0018 0.0183 0.0568
Giardia lamblia Cathepsin L precursor 0.0018 0.0183 0.0568
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0469 0.1538
Trypanosoma brucei unspecified product 0.0025 0.0294 0.0944
Echinococcus multilocularis lamin dm0 0.0023 0.0263 0.0248
Entamoeba histolytica recQ family helicase, putative 0.003 0.0362 0.2722
Schistosoma mansoni hypothetical protein 0.0019 0.0193 0.0178
Echinococcus granulosus GPCR family 2 0.0015 0.0134 0.0119
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0489 0.0475
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0032 0.0396 0.0415
Trichomonas vaginalis CAMK family protein kinase 0.009 0.1287 0.3808
Entamoeba histolytica cysteine protease, putative 0.0018 0.0183 0.1318
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0038 0.0489 0.1606
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0183 0.0542
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0489 0.0517
Entamoeba histolytica cysteine protease, putative 0.0018 0.0183 0.1318
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0183 0.0568
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.0469 0.0495
Loa Loa (eye worm) hypothetical protein 0.0018 0.0183 0.0183
Giardia lamblia Cathepsin L-like protease 0.0018 0.0183 0.0568
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0469 0.1538
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0036 0.0453 0.1484
Brugia malayi hypothetical protein 0.0009 0.0049 0.0036
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0018 0.0183 0.0183
Loa Loa (eye worm) hypothetical protein 0.0019 0.0193 0.0194
Plasmodium falciparum cysteine proteinase falcipain 3 0.0018 0.0183 0.3695
Onchocerca volvulus 0.0023 0.0263 0.0736
Trypanosoma cruzi DNA polymerase eta, putative 0.0061 0.0842 0.0902
Echinococcus multilocularis nibrin 0.0009 0.0049 0.0033
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0183 0.1318
Echinococcus granulosus dna polymerase kappa 0.0037 0.0469 0.0455
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0183 0.0542
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0008 0.0025 0.001
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0183 0.0183
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0018 0.0183 0.3827
Schistosoma mansoni inositol monophosphatase 0.0032 0.0396 0.0381
Schistosoma mansoni intermediate filament proteins 0.0023 0.0263 0.0248
Schistosoma mansoni ap endonuclease 0.0036 0.0453 0.0439
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0183 0.0542
Onchocerca volvulus 0.0018 0.0183 0.0498
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0183 0.0542
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0007 0.0016 0.0046
Brugia malayi hypothetical protein 0.0009 0.0049 0.0036
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0183 0.0542
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.009 0.1287 0.1273
Giardia lamblia DINP protein human, muc B family 0.0037 0.0469 0.1538
Entamoeba histolytica cysteine protease, putative 0.0018 0.0183 0.1318
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0183 0.0168
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0015 0.0134 0.0402
Trichomonas vaginalis CAMK family protein kinase 0.009 0.1287 0.3808
Schistosoma mansoni inositol monophosphatase 0.0032 0.0396 0.0381
Brugia malayi polk-prov protein 0.0011 0.008 0.007
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0051 0.0035
Echinococcus granulosus JmjC domain containing protein 4 0.0015 0.0134 0.0119
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0183 0.0542
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0007 0.0016 0.0046
Entamoeba histolytica hypothetical protein 0.0069 0.0954 0.7385
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0053 0.0712 0.0698
Schistosoma mansoni rab6-interacting 0.0019 0.0193 0.0178
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.02 0.2966 0.2955
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0032 0.0396 0.1171
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0183 0.0542
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0032 0.039 0.0409
Schistosoma mansoni hypothetical protein 0.0391 0.5888 0.5882
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0489 0.3728
Echinococcus granulosus inositol monophosphatase 1 0.0032 0.0396 0.0381
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0183 0.0183
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0036 0.0453 0.2251
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0011 0.008 0.0219
Brugia malayi jmjC domain containing protein 0.0015 0.0134 0.0129
Onchocerca volvulus 0.0018 0.0183 0.0498
Echinococcus multilocularis lysine specific demethylase 5A 0.0056 0.0765 0.0751
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0183 0.0168
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0183 0.0542
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0183 0.0542
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0011 0.008 0.0219
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0134 0.0119
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0049 0.0037
Plasmodium falciparum DNA repair protein REV1, putative 0.0011 0.008 0.1422
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0031 0.0379 0.0397
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0183 0.0183
Entamoeba histolytica cysteine proteinase 2 0.0018 0.0183 0.1318
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0183 0.0542
Echinococcus multilocularis bloom syndrome protein 0.0039 0.0507 0.0492
Giardia lamblia Cysteine protease 0.0018 0.0183 0.0568
Loa Loa (eye worm) hypothetical protein 0.0019 0.0193 0.0194
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0183 0.0542
Brugia malayi hypothetical protein 0.0144 0.2102 0.2276
Entamoeba histolytica hypothetical protein 0.0069 0.0954 0.7385
Brugia malayi cathepsin L-like precursor 0.0018 0.0183 0.0183
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0469 0.1538
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0183 0.0542
Schistosoma mansoni protein phosphatase 2C 0.0015 0.0134 0.0119
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0606 0.9182 0.918
Giardia lamblia Cysteine protease 0.0018 0.0183 0.0568
Schistosoma mansoni phosphatidylserine receptor 0.0015 0.0134 0.0119
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0183 0.0168
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0183 0.0183
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0036 0.0453 0.0439
Onchocerca volvulus 0.0018 0.0183 0.0498
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0036 0.0453 1
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.0061 0.0837 1
Onchocerca volvulus 0.0029 0.0351 0.0996
Plasmodium vivax serine-repeat antigen (SERA) 0.0018 0.0183 0.3827
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0351 0.0336
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0183 0.0542
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0183 0.0568
Leishmania major DNA polymerase kappa, putative 0.0011 0.008 0.0219
Leishmania major cathepsin L-like protease 0.0018 0.0183 0.0568
Plasmodium falciparum cysteine proteinase falcipain 1 0.0018 0.0183 0.3695
Onchocerca volvulus 0.0019 0.0193 0.0528
Loa Loa (eye worm) hypothetical protein 0.0018 0.0183 0.0183
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0037 0.0469 0.2479
Onchocerca volvulus 0.0018 0.0183 0.0498
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0018 0.0183 0.0568
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.008 0.0219
Entamoeba histolytica cysteine protease, putative 0.0018 0.0183 0.1318
Loa Loa (eye worm) hypothetical protein 0.0009 0.0049 0.0036
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0294 0.0944
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.009 0.1287 0.1387
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0049 0.0145
Brugia malayi CCR4 0.0007 0.0017 0.0002
Trypanosoma brucei DNA polymerase IV, putative 0.0037 0.0469 0.1538
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0027 0.0324 0.1044
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0193 0.0178
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0018 0.0183 0.0183
Giardia lamblia Cathepsin L-like protease 0.0018 0.0183 0.0568
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0032 0.0396 0.1288
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0183 0.0568
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0183 0.0542
Loa Loa (eye worm) intermediate filament protein 0.0023 0.0263 0.027
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0489 0.0475
Trypanosoma brucei hypothetical protein, conserved 0.0011 0.008 0.0219
Brugia malayi Bloom's syndrome protein homolog 0.0039 0.0507 0.0536
Treponema pallidum exodeoxyribonuclease (exoA) 0.0036 0.0453 1
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0031 0.0379 0.1232
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0183 0.0168
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0183 0.0168
Schistosoma mansoni polycystin 1-related 0.0019 0.0193 0.0178
Toxoplasma gondii cathepsin CPC2 0.0018 0.0183 0.0568
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0183 0.0542
Loa Loa (eye worm) hypothetical protein 0.0018 0.0183 0.0183
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0018 0.0183 0.0168
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0183 0.0568
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0183 0.0542
Loa Loa (eye worm) RecQ helicase 0.0039 0.0507 0.0536
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0351 0.0336
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0018 0.0183 0.3827
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0027 0.0324 0.0336
Toxoplasma gondii cathepsin CPL 0.0018 0.0183 0.0568
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0037 0.0469 0.0455
Brugia malayi Cathepsin L-like precursor 0.0018 0.0183 0.0183
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0469 0.1538
Entamoeba histolytica cysteine protease, putative 0.0018 0.0183 0.1318
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0015 0.0134 0.0402
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0018 0.0183 0.0183
Treponema pallidum DNA ligase (lig) 0.0009 0.0049 0.076
Trichomonas vaginalis CAMK family protein kinase 0.009 0.1287 0.3808
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.003 0.0362 0.0377
Plasmodium vivax vivapain-3 0.0018 0.0183 0.3827
Loa Loa (eye worm) hypothetical protein 0.0014 0.0118 0.0112
Echinococcus multilocularis lamin 0.0023 0.0263 0.0248
Brugia malayi CXXC zinc finger family protein 0.0027 0.0325 0.0338
Leishmania major cysteine peptidase A (CPA) 0.0018 0.0183 0.0568
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0009 0.0049 0.0145
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0018 0.0183 0.0183
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.009 0.1287 0.4308
Toxoplasma gondii cathepsin CPC1 0.0018 0.0183 0.0568
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0489 0.0517
Trypanosoma brucei unspecified product 0.0025 0.0294 0.0944
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0183 0.1318
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0183 0.0568
Schistosoma mansoni topbp1 0.0009 0.0049 0.0033
Onchocerca volvulus 0.0009 0.0049 0.0099
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0134 0.0129
Echinococcus multilocularis inositol monophosphatase 1 0.0032 0.0396 0.0381
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0056 0.0765 0.0751
Brugia malayi hypothetical protein 0.0019 0.0193 0.0194
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0052 0.0125
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.00000000017268 0.00000000051101
Schistosoma mansoni microtubule-associated protein tau 0.066 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0183 0.0542
Brugia malayi Pax transcription activation domain interacting protein 0.0009 0.0049 0.0036
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.008 0.007
Echinococcus granulosus dnaJ subfamily B 0.0391 0.5888 0.5882
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.0118 0.0348
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0032 0.0396 0.8574
Schistosoma mansoni lipoxygenase 0.0053 0.0712 0.0698
Entamoeba histolytica hypothetical protein 0.0069 0.0954 0.7385
Trypanosoma cruzi DNA polymerase eta, putative 0.0036 0.0453 0.0477
Brugia malayi Cathepsin L-like precursor 0.0018 0.0183 0.0183
Trypanosoma brucei unspecified product 0.0037 0.0469 0.1538
Entamoeba histolytica cysteine protease, putative 0.0018 0.0183 0.1318
Brugia malayi ImpB/MucB/SamB family protein 0.0037 0.0469 0.0495
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.00000000017268 0.00000000051101
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0183 0.0168
Entamoeba histolytica cysteine proteinase 1, putative 0.0018 0.0183 0.1318
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0183 0.0168
Schistosoma mansoni topbp1 0.0009 0.0049 0.0033
Echinococcus multilocularis geminin 0.0323 0.4848 0.484
Plasmodium falciparum serine repeat antigen 7 0.0018 0.0183 0.3695
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0055 0.0744 0.073
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0.00000000017268 0.00000000051101
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.0812 0.0798
Leishmania major DNA polymerase kappa, putative 0.0037 0.0469 0.1538
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0047 0.063 0.067
Onchocerca volvulus 0.0018 0.0183 0.0498
Echinococcus granulosus ubiquitin specific protease 41 0.0038 0.0489 0.0475
Chlamydia trachomatis DNA ligase 0.0009 0.0049 0.5
Loa Loa (eye worm) hypothetical protein 0.0018 0.0183 0.0183
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0134 0.0129
Giardia lamblia Encystation-specific protease 0.0018 0.0183 0.0568
Brugia malayi Cathepsin L-like precursor 0.0018 0.0183 0.0183
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0183 0.1318
Brugia malayi serine/threonine-protein kinase plk-2 0.009 0.1287 0.1387
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.0351 0.0336
Loa Loa (eye worm) hypothetical protein 0.0011 0.0078 0.0068
Echinococcus granulosus lamin dm0 0.0023 0.0263 0.0248
Mycobacterium ulcerans hypothetical protein 0.0011 0.008 0.0174
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0118 0.0112
Loa Loa (eye worm) hypothetical protein 0.0023 0.0257 0.0263
Loa Loa (eye worm) hypothetical protein 0.0023 0.0263 0.027
Trypanosoma brucei polo-like protein kinase 0.009 0.1287 0.4308
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0023 0.0264 0.5667
Entamoeba histolytica cysteine protease, putative 0.0018 0.0183 0.1318
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0018 0.0183 0.3695
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0027 0.0324 0.6794
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0049 0.0145
Schistosoma mansoni rab6-interacting 0.0019 0.0193 0.0178
Toxoplasma gondii ATPase, AAA family protein 0.0009 0.0049 0.0113
Brugia malayi Inositol-1 0.0032 0.0396 0.0415
Echinococcus granulosus lysine specific demethylase 6a 0.0015 0.0134 0.0119
Loa Loa (eye worm) hypothetical protein 0.0011 0.0071 0.0061
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0018 0.0183 0.1318
Entamoeba histolytica cysteine protease, putative 0.0018 0.0183 0.1318
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.0469 0.0495
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0023 0.0256 0.0813
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.02 0.2966 1
Schistosoma mansoni hypothetical protein 0.0069 0.0954 0.094
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.00000000017268 0.00000000051101
Leishmania major cathepsin L-like protease 0.0018 0.0183 0.0568
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.003 0.0362 0.1172
Onchocerca volvulus 0.0227 0.3379 1
Echinococcus granulosus phd:f box containing protein 0.0015 0.0134 0.0119
Brugia malayi Doublecortin family protein 0.0019 0.0193 0.0194
Entamoeba histolytica hypothetical protein 0.0018 0.0183 0.1318
Brugia malayi Intermediate filament tail domain containing protein 0.0023 0.0263 0.027
Loa Loa (eye worm) fibroinase 0.0018 0.0183 0.0183
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0027 0.0324 0.1044
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0055 0.0744 0.3979
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0018 0.0183 0.0568
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0183 0.0568
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0127 0.1846 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0018 0.0183 0.1318
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0193 0.0178
Brugia malayi Calcitonin receptor-like protein seb-1 0.0047 0.063 0.067
Schistosoma mansoni cathepsin S (C01 family) 0.0018 0.0183 0.0168
Trichomonas vaginalis replication factor C large subunit, putative 0.0009 0.0049 0.0145
Echinococcus granulosus cathepsin b 0.0606 0.9182 0.918
Loa Loa (eye worm) hypothetical protein 0.0015 0.0134 0.0129
Schistosoma mansoni lamin 0.0023 0.0263 0.0248
Plasmodium falciparum serine repeat antigen 8 0.0018 0.0183 0.3695
Entamoeba histolytica cysteine protease, putative 0.0018 0.0183 0.1318
Brugia malayi cathepsin F-like cysteine proteinase 0.0018 0.0183 0.0183
Entamoeba histolytica serine/threonine protein kinase, putative 0.009 0.1287 1
Echinococcus granulosus dna polymerase eta 0.0061 0.0842 0.0828
Giardia lamblia Replication factor C, subunit 1 0.0009 0.0049 0.0113
Schistosoma mansoni hypothetical protein 0.0015 0.0134 0.0119
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0018 0.0183 0.0542
Giardia lamblia DNA damage repair protein 0.0011 0.008 0.0219
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0018 0.0183 0.0542
Echinococcus multilocularis dnaJ subfamily B 0.0391 0.5888 0.5882
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.0469 0.0495
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0193 0.0178
Plasmodium falciparum serine repeat antigen 5 0.0018 0.0183 0.3695
Plasmodium falciparum serine repeat antigen 6 0.0018 0.0183 0.3695
Giardia lamblia Cathepsin L precursor 0.0018 0.0183 0.0568
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0489 0.1606
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0018 0.0183 0.0168
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0032 0.0396 0.1171
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0032 0.0396 0.0415
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.02 0.2966 0.8778
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0134 0.0129
Schistosoma mansoni loxhd1 0.0019 0.0193 0.0178
Echinococcus granulosus cathepsin L 0.0018 0.0183 0.0168
Entamoeba histolytica recQ family helicase, putative 0.0013 0.011 0.0744
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0.00000000017268 0.00000000051101
Echinococcus granulosus mixed lineage leukemia protein mll 0.0008 0.0025 0.001
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0017 0.0158 0.0143
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0031 0.0379 0.1232
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0183 0.0183
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0183 0.1318
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0009 0.0049 0.0113
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0007 0.0016 0.0046
Giardia lamblia Cathepsin B precursor 0.0018 0.0183 0.0568
Brugia malayi Pre-SET motif family protein 0.0029 0.0351 0.0366
Plasmodium vivax JmjC domain containing protein 0.0015 0.0134 0.2711
Trypanosoma brucei DNA damage repair protein, putative 0.0011 0.008 0.0219
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0018 0.0183 0.0542
Schistosoma mansoni ap endonuclease 0.0036 0.0453 0.0439
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0183 0.0542
Plasmodium vivax ATP-dependent DNA helicase Q1, putative 0.0013 0.011 0.216
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0018 0.0183 0.3827
Loa Loa (eye worm) hypothetical protein 0.0015 0.0134 0.0129
Leishmania major cathepsin L-like protease 0.0018 0.0183 0.0568
Loa Loa (eye worm) hypothetical protein 0.0038 0.0489 0.0517
Entamoeba histolytica cysteine protease, putative 0.0018 0.0183 0.1318
Schistosoma mansoni rotamase 0.0032 0.039 0.0375
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0134 0.0129
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0183 0.0168
Schistosoma mansoni cpg binding protein 0.0027 0.0325 0.031
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0052 0.0125
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0056 0.0765 0.0751
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0027 0.0324 0.0336
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0036 0.0453 0.3444
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0183 0.0568
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.00000000017268 0.00000000051101
Echinococcus granulosus cathepsin L 0.0018 0.0183 0.0168
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0183 0.0498
Brugia malayi Cathepsin L-like precursor 0.0018 0.0183 0.0183
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0009 0.0049 0.0036
Loa Loa (eye worm) hypothetical protein 0.0009 0.0049 0.0036
Schistosoma mansoni blooms syndrome DNA helicase 0.0014 0.0118 0.0103
Echinococcus granulosus lysine specific demethylase 5A 0.0058 0.0789 0.0775
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0049 0.0145
Trypanosoma cruzi DNA damage repair protein, putative 0.0011 0.008 0.007
Plasmodium falciparum JmjC domain-containing protein, putative 0.0015 0.0134 0.2618
Giardia lamblia Cathepsin B precursor 0.0018 0.0183 0.0568
Trichomonas vaginalis CAMK family protein kinase 0.009 0.1287 0.3808
Echinococcus granulosus bloom syndrome protein 0.0039 0.0507 0.0492
Plasmodium vivax unspecified product 0.0018 0.0183 0.3827
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0183 0.0183
Loa Loa (eye worm) hypothetical protein 0.0029 0.0351 0.0366
Onchocerca volvulus 0.0019 0.0193 0.0528
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0051 0.0688 0.0733
Brugia malayi hypothetical protein 0.0069 0.0954 0.1024
Plasmodium vivax vivapain-1 0.0018 0.0183 0.3827
Echinococcus granulosus replication factor c subunit 1 0.0009 0.0049 0.0033
Trypanosoma brucei cysteine peptidase C (CPC) 0.02 0.2966 1
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0055 0.0744 0.0795
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0183 0.0498
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0037 0.0469 0.1389
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0007 0.0016 0.0046
Trichomonas vaginalis CAMK family protein kinase 0.0045 0.0589 0.1743
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0134 0.0119
Echinococcus granulosus lamin 0.0023 0.0263 0.0248
Entamoeba histolytica cysteine protease, putative 0.0018 0.0183 0.1318
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.001 0.0052 0.004
Entamoeba histolytica hypothetical protein 0.0069 0.0954 0.7385
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0351 0.0336
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0183 0.0542
Trichomonas vaginalis DNA helicase recq1, putative 0.0039 0.0507 0.15
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0027 0.0324 0.0309
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0183 0.1318
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0489 0.1448
Echinococcus granulosus jumonji domain containing 1A 0.0015 0.0134 0.0119
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0036 0.0453 0.0439
Schistosoma mansoni jumonji domain containing protein 0.0056 0.0765 0.0751
Entamoeba histolytica cysteine protease, putative 0.0018 0.0183 0.1318
Schistosoma mansoni DNA polymerase eta 0.0061 0.0842 0.0828
Trypanosoma cruzi DNA polymerase kappa, putative 0.0037 0.0469 0.0495
Trichomonas vaginalis DNA helicase recq, putative 0.0039 0.0507 0.15
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0134 0.0129
Trichomonas vaginalis rotamase, putative 0.0032 0.039 0.1155
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0183 0.0542
Giardia lamblia Cathepsin B precursor 0.0018 0.0183 0.0568
Trypanosoma brucei DNA polymerase IV, putative 0.0037 0.0469 0.1538
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0183 0.0183
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0183 0.0542
Echinococcus granulosus cathepsin l1 0.0018 0.0183 0.0168
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0193 0.3919
Entamoeba histolytica cysteine protease, putative 0.0018 0.0183 0.1318
Loa Loa (eye worm) hypothetical protein 0.0009 0.0049 0.0036
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0018 0.0183 0.0183
Trypanosoma brucei beta lactamase 0.0061 0.0837 0.2783
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0183 0.0542
Loa Loa (eye worm) hypothetical protein 0.0047 0.063 0.067
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0183 0.0542
Entamoeba histolytica cysteine protease, putative 0.0018 0.0183 0.1318
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0183 0.0542
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0469 0.1538
Brugia malayi cytoplasmic intermediate filament protein 0.0013 0.0097 0.0089
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0036 0.0453 0.2392
Echinococcus granulosus RUN 0.0019 0.0193 0.0178
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0134 0.0129
Treponema pallidum ATP-dependent DNA helicase 0.0014 0.0118 0.2346
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0031 0.0379 0.2859
Trichomonas vaginalis ap endonuclease, putative 0.0036 0.0453 0.1342
Loa Loa (eye worm) hypothetical protein 0.0018 0.0183 0.0183
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0183 0.0568
Schistosoma mansoni hypothetical protein 0.0015 0.0134 0.0119
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0009 0.0049 0.0262
Echinococcus multilocularis ubiquitin specific protease 41 0.0038 0.0489 0.0475
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0018 0.0183 0.0568
Brugia malayi Cathepsin L-like precursor 0.0018 0.0183 0.0183
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0183 0.0168
Schistosoma mansoni hypothetical protein 0.0032 0.04 0.0385
Loa Loa (eye worm) cysteine protease 0.0018 0.0183 0.0183
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0489 0.1448
Trypanosoma cruzi FHA domain containing protein, putative 0.0009 0.0049 0.0036
Plasmodium falciparum serine repeat antigen 9 0.0018 0.0183 0.3695
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0183 0.0542
Onchocerca volvulus Cathepsin F homolog 0.0018 0.0183 0.0498
Echinococcus multilocularis cathepsin b 0.0606 0.9182 0.918
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0018 0.0183 0.3827
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0183 0.0542
Leishmania major cathepsin L-like protease 0.0018 0.0183 0.0568
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0037 0.0469 0.0455
Schistosoma mansoni cpg binding protein 0.0029 0.0349 0.0334
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0351 0.0336
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.008 0.007
Loa Loa (eye worm) hypothetical protein 0.0015 0.0134 0.0129
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0183 0.0168
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0183 0.0183
Brugia malayi ImpB/MucB/SamB family protein 0.0061 0.0842 0.0902
Trypanosoma cruzi major cysteine proteinase, putative 0.0018 0.0183 0.0183
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0351 0.1136
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0055 0.0744 0.3868
Brugia malayi intermediate filament protein 0.0023 0.0263 0.027
Echinococcus granulosus cysteine protease 0.0018 0.0183 0.0168
Schistosoma mansoni jumonji/arid domain-containing protein 0.0058 0.0789 0.0775
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0017 0.0158 0.0143
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0183 0.0168
Loa Loa (eye worm) histone methyltransferase 0.001 0.0051 0.0039
Plasmodium vivax serine-repeat antigen (SERA) 0.0018 0.0183 0.3827
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0069 0.0954 0.094
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0036 0.0453 0.1484
Schistosoma mansoni lamin 0.0023 0.0263 0.0248
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0183 0.0542
Echinococcus multilocularis RUN 0.0019 0.0193 0.0178
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.0183 0.0183
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0294 0.0944
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0183 0.0542
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0053 0.0712 0.0698
Giardia lamblia Kinase, PLK 0.009 0.1287 0.4308
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0027 0.0324 0.0336
Schistosoma mansoni chromosome transmission fidelity factor 0.0009 0.0049 0.0033
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0055 0.0744 0.3868
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0036 0.0453 0.9656
Echinococcus granulosus geminin 0.0323 0.4848 0.484
Schistosoma mansoni hypothetical protein 0.0323 0.4848 0.484
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0037 0.0469 1
Schistosoma mansoni cathepsin C 0.0018 0.0183 0.0168
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0134 0.0119
Plasmodium vivax DNA repair protein REV1, putative 0.0011 0.008 0.1473
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0018 0.0183 0.0568
Giardia lamblia Cathepsin B precursor 0.0018 0.0183 0.0568
Brugia malayi topoisomerase 0.0009 0.0049 0.0036
Echinococcus multilocularis dna polymerase kappa 0.0037 0.0469 0.0455
Trypanosoma brucei DNA damage repair protein, putative 0.0011 0.008 0.0219
Onchocerca volvulus Serine\/threonine kinase homolog 0.009 0.1287 0.3779
Schistosoma mansoni blooms syndrome DNA helicase 0.0025 0.0293 0.0278
Leishmania major cathepsin L-like protease 0.0018 0.0183 0.0568
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0183 0.0183
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0469 0.1538
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0183 0.0168
Giardia lamblia Hypothetical protein 0.0018 0.0183 0.0568
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0036 0.0453 0.0478
Echinococcus multilocularis cpg binding protein 0.0029 0.0349 0.0334
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0015 0.0134 0.0129
Brugia malayi jmjC domain containing protein 0.0056 0.0765 0.0818
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0183 0.0183
Schistosoma mansoni cathepsin B (C01 family) 0.0018 0.0183 0.0168
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0469 0.1538
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0183 0.0183
Plasmodium vivax unspecified product 0.0018 0.0183 0.3827
Loa Loa (eye worm) hypothetical protein 0.0606 0.9182 1
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0127 0.1846 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0183 0.0542
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0049 0.0036
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0489 0.1448
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0032 0.0396 0.1288
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0018 0.0183 0.3827
Onchocerca volvulus 0.0018 0.0183 0.0498
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0183 0.0568
Loa Loa (eye worm) hypothetical protein 0.0061 0.0842 0.0902
Mycobacterium ulcerans DNA polymerase IV 0.0037 0.0469 0.234
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0183 0.0542
Plasmodium falciparum serine repeat antigen 4 0.0018 0.0183 0.3695
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0032 0.039 0.0409
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0007 0.0016 0.0046
Brugia malayi Pre-SET motif family protein 0.02 0.2959 0.3211
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0007 0.0017 0.0051
Trichomonas vaginalis CAMK family protein kinase 0.009 0.1287 0.3808
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0489 0.0517
Onchocerca volvulus 0.0018 0.0183 0.0498
Schistosoma mansoni terminal deoxycytidyl transferase 0.0037 0.0469 0.0455
Echinococcus granulosus intermediate filament protein 0.0023 0.0263 0.0248
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0183 0.0542
Brugia malayi fibroinase precursor 0.0018 0.0183 0.0183
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0009 0.0049 0.0036
Schistosoma mansoni DNA ligase IV 0.0009 0.0049 0.0033
Echinococcus granulosus cpg binding protein 0.0029 0.0349 0.0334
Leishmania major DNA damage repair protein, putative 0.0011 0.008 0.0219
Giardia lamblia Cathepsin B precursor 0.02 0.2966 1
Plasmodium vivax vivapain-2 0.0018 0.0183 0.3827
Loa Loa (eye worm) hypothetical protein 0.0009 0.0049 0.0036
Leishmania major cathepsin L-like protease 0.0018 0.0183 0.0568
Trypanosoma cruzi hypothetical protein, conserved 0.0009 0.0049 0.0036
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0018 0.0183 0.3695
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.0789 0.0844
Loa Loa (eye worm) hypothetical protein 0.0018 0.0183 0.0183
Entamoeba histolytica cysteine protease, putative 0.0018 0.0183 0.1318
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0183 0.0168
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0007 0.0016 0.0046
Trypanosoma cruzi cruzipain precursor, putative 0.0018 0.0183 0.0183
Giardia lamblia Cathepsin L precursor 0.0018 0.0183 0.0568
Loa Loa (eye worm) hypothetical protein 0.0144 0.2102 0.2276
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0489 0.1606
Leishmania major cathepsin L-like protease 0.0018 0.0183 0.0568
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0032 0.0396 0.1288
Brugia malayi Cathepsin L-like precursor 0.0018 0.0183 0.0183
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0009 0.0049 0.0145
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0037 0.0469 0.1538
Giardia lamblia Cathepsin L precursor 0.0018 0.0183 0.0568
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0183 0.1318
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0606 0.9182 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0018 0.0183 0.0542
Loa Loa (eye worm) inositol-1 0.0032 0.0396 0.0415
Entamoeba histolytica cysteine protease, putative 0.0018 0.0183 0.1318
Giardia lamblia Cathepsin B precursor 0.02 0.2966 1
Trichomonas vaginalis CAMK family protein kinase 0.009 0.1287 0.3808
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0183 0.0568
Brugia malayi Cathepsin L-like cysteine proteinase 0.0018 0.0183 0.0183
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0183 0.0542
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0055 0.0744 0.073
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0051 0.0035
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0183 0.0542
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0183 0.0542
Trichomonas vaginalis ap endonuclease, putative 0.0036 0.0453 0.1342
Entamoeba histolytica deoxycytidyl transferase, putative 0.0037 0.0469 0.3571
Schistosoma mansoni lipoxygenase 0.0019 0.0193 0.0178
Trichomonas vaginalis Phospholipase C precursor, putative 0.0007 0.0016 0.0046
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0489 0.0475
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0183 0.0542
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0055 0.0744 0.2469
Leishmania major cathepsin L-like protease 0.0018 0.0183 0.0568
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0183 0.0542
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0027 0.0324 0.0309
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.001 0.0052 0.0125
Plasmodium falciparum serine repeat antigen 1 0.0018 0.0183 0.3695
Brugia malayi DKFZp564C0469 protein 0.0009 0.0049 0.0036
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0015 0.0134 0.0119
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0193 0.0194
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.001 0.0052 0.004
Echinococcus multilocularis musashi 0.0023 0.0263 0.0248
Schistosoma mansoni kinase 0.0046 0.0607 0.0592
Plasmodium vivax replication factor C subunit 1, putative 0.0009 0.0049 0.076
Schistosoma mansoni transcription factor LCR-F1 0.0069 0.0954 0.094
Loa Loa (eye worm) ctsf protein 0.0018 0.0183 0.0183
Schistosoma mansoni hypothetical protein 0.0015 0.0134 0.0119
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0134 0.0119
Toxoplasma gondii preprocathepsin c precursor, putative 0.0018 0.0183 0.0568
Trichomonas vaginalis DNA polymerase eta, putative 0.0037 0.0469 0.1389
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0009 0.0049 0.0145
Trypanosoma brucei chrX additional, unordered contigs 0.0011 0.008 0.0219
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0038 0.0489 0.0475
Brugia malayi jmjC domain containing protein 0.0015 0.0134 0.0129
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0469 0.1538
Trichomonas vaginalis CAMK family protein kinase 0.009 0.1287 0.3808
Toxoplasma gondii cathepsin B 0.02 0.2966 1
Echinococcus multilocularis cathepsin L 0.0018 0.0183 0.0168
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0606 0.9182 0.918
Echinococcus multilocularis expressed protein 0.0032 0.039 0.0375
Brugia malayi Cathepsin L-like precursor 0.0018 0.0183 0.0183
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0047 0.063 0.067
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0011 0.0078 0.0062
Loa Loa (eye worm) jmjC domain-containing protein 0.0015 0.0134 0.0129
Echinococcus granulosus cathepsin L cysteine protease 0.0018 0.0183 0.0168
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0018 0.0183 0.0168
Echinococcus multilocularis cathepsin L 0.0018 0.0183 0.0168
Loa Loa (eye worm) hypothetical protein 0.0009 0.0049 0.0036
Loa Loa (eye worm) hypothetical protein 0.0011 0.008 0.007
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0118 0.0112
Trypanosoma brucei DNA polymerase IV, putative 0.0037 0.0469 0.1538
Echinococcus multilocularis cathepsin b 0.0606 0.9182 0.918
Entamoeba histolytica hypothetical protein 0.0009 0.0049 0.0262
Echinococcus multilocularis lysine specific demethylase 6a 0.0015 0.0134 0.0119
Brugia malayi latrophilin 2 splice variant baaae 0.0032 0.04 0.042
Loa Loa (eye worm) CXXC zinc finger family protein 0.0027 0.0325 0.0338
Echinococcus multilocularis dna polymerase eta 0.0061 0.0842 0.0828
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0031 0.0379 0.0397
Schistosoma mansoni DNA polymerase IV / kappa 0.0011 0.008 0.0065
Loa Loa (eye worm) hypothetical protein 0.0015 0.0134 0.0129
Trypanosoma cruzi major cysteine proteinase, putative 0.0018 0.0183 0.0183
Entamoeba histolytica recQ family DNA helicase 0.0014 0.0118 0.0808
Mycobacterium tuberculosis Conserved hypothetical protein 0.0037 0.0469 0.2479
Loa Loa (eye worm) cathepsin B 0.02 0.2966 0.3219
Trichomonas vaginalis rotamase, putative 0.0031 0.0379 0.1122
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0049 0.0145
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0029 0.0344 0.1796
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0027 0.0324 0.0309
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0183 0.0542
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0025 0.001
Brugia malayi cathepsin B-like cysteine proteinase 0.0606 0.9182 1
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0183 0.0183
Giardia lamblia Cathepsin L precursor 0.0018 0.0183 0.0568
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0018 0.0183 0.3695
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0183 0.0542
Onchocerca volvulus 0.0144 0.2102 0.6203
Schistosoma mansoni serine/threonine protein kinase 0.009 0.1287 0.1273
Echinococcus granulosus nibrin 0.0009 0.0049 0.0033
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0183 0.0168
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0183 0.0542
Mycobacterium ulcerans DNA polymerase IV 0.0037 0.0469 0.234
Loa Loa (eye worm) hypothetical protein 0.0026 0.0302 0.0312
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0018 0.0183 0.3827
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0183 0.0168
Echinococcus granulosus expressed protein 0.0032 0.039 0.0375
Echinococcus granulosus cathepsin b 0.0606 0.9182 0.918
Echinococcus multilocularis cysteine protease 0.0018 0.0183 0.0168
Giardia lamblia Hypothetical protein 0.0018 0.0183 0.0568
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.02 0.2966 0.3219
Loa Loa (eye worm) hypothetical protein 0.0027 0.0324 0.0336
Giardia lamblia Cathepsin B precursor 0.0018 0.0183 0.0568
Plasmodium falciparum serine repeat antigen 2 0.0018 0.0183 0.3695
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0027 0.0325 0.031
Brugia malayi Cathepsin L-like precursor 0.0018 0.0183 0.0183
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0036 0.0453 0.0478
Onchocerca volvulus 0.0018 0.0183 0.0498
Trypanosoma cruzi cysteine protease, putative 0.0018 0.0183 0.0183
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0606 0.9182 0.918
Plasmodium falciparum replication factor C subunit 1, putative 0.0009 0.0049 0.0734
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0183 0.0542
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0351 0.0336
Trichomonas vaginalis set domain proteins, putative 0.0227 0.3379 1
Schistosoma mansoni hypothetical protein 0.0015 0.0134 0.0119
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0183 0.0183
Giardia lamblia Cysteine protease 0.0018 0.0183 0.0568
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.0717 0.2377
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0018 0.0183 0.3827
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0049 0.0145
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0183 0.0568
Trypanosoma brucei DNA polymerase eta, putative 0.0061 0.0842 0.2801
Entamoeba histolytica cysteine protease, putative 0.0018 0.0183 0.1318
Entamoeba histolytica cysteine protease, putative 0.0018 0.0183 0.1318
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0036 0.0453 0.0478
Onchocerca volvulus 0.0027 0.0325 0.092
Trichomonas vaginalis inositol monophosphatase, putative 0.0032 0.0396 0.1171
Leishmania major DNA polymerase eta, putative 0.0036 0.0453 0.1482
Trypanosoma brucei DNA polymerase kappa, putative 0.0037 0.0469 0.1538
Toxoplasma gondii exonuclease III APE 0.0036 0.0453 0.1484
Onchocerca volvulus 0.0023 0.0263 0.0736
Onchocerca volvulus 0.001 0.0054 0.0116
Loa Loa (eye worm) hypothetical protein 0.0032 0.04 0.042
Echinococcus multilocularis cysteine protease 0.0018 0.0183 0.0168
Entamoeba histolytica cysteine protease, putative 0.0018 0.0183 0.1318
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0009 0.0049 0.0113
Plasmodium vivax SET domain protein, putative 0.0029 0.0351 0.7654
Echinococcus multilocularis jumonji domain containing 1A 0.0015 0.0134 0.0119
Loa Loa (eye worm) hypothetical protein 0.0018 0.0183 0.0183
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0183 0.0568
Giardia lamblia Cathepsin L precursor 0.0018 0.0183 0.0568
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0183 0.0498
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0032 0.0396 0.193
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0489 0.0475
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0011 0.0078 0.0062
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0036 0.0453 0.1484
Echinococcus multilocularis GPCR, family 2 0.0015 0.0134 0.0119
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0007 0.0017 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.039 0.1155
Loa Loa (eye worm) hypothetical protein 0.0018 0.0183 0.0183
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0027 0.0324 0.0309
Plasmodium falciparum serine repeat antigen 3 0.0018 0.0183 0.3695
Trypanosoma brucei DNA polymerase kappa, putative 0.0025 0.0294 0.0944
Trypanosoma brucei hypothetical protein, conserved 0.0011 0.008 0.0219
Echinococcus multilocularis microtubule associated protein 2 0.066 1 1
Mycobacterium ulcerans lipoprotein LpqF 0.0061 0.0837 0.4383
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0018 0.0183 0.3695
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0008 0.0025 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0183 0.0542
Giardia lamblia Sgs1 DNA helicase, putative 0.0027 0.0324 0.1044
Trichomonas vaginalis DNA helicase recq, putative 0.003 0.0362 0.107
Echinococcus granulosus cathepsin l1 0.0018 0.0183 0.0168
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0013 0.0097 0.0089
Schistosoma mansoni phd/f-box containing protein 0.0015 0.0134 0.0119
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0018 0.0183 0.3827
Wolbachia endosymbiont of Brugia malayi parvulin-like peptidyl-prolyl isomerase, PPID 0.001 0.0052 0.009
Brugia malayi jmjC domain containing protein 0.0015 0.0134 0.0129
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0193 0.4058
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0018 0.0183 0.3695
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0183 0.0542
Trypanosoma brucei DNA polymerase kappa, putative 0.0011 0.008 0.0219

Activities

Activity type Activity value Assay description Source Reference
Binding activity (binding) = 32 % Displacement of [3H]-NBTI from human erythrocyte membrane at 10 uM ChEMBL. 15481982
Binding activity (binding) = 32 % Displacement of [3H]-NBTI from human erythrocyte membrane at 10 uM ChEMBL. 15481982

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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