Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.0536 | 0.0536 |
Brugia malayi | cathepsin L precursor | 0.0036 | 0.0059 | 0.0059 |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.0536 | 0.0536 |
Leishmania major | farnesyl pyrophosphate synthase | 0.0124 | 0.1057 | 0.3372 |
Brugia malayi | Cathepsin L-like precursor | 0.0061 | 0.0342 | 0.0342 |
Brugia malayi | cathepsin L-like cysteine proteinase | 0.0036 | 0.0059 | 0.0059 |
Schistosoma mansoni | cathepsin C | 0.0036 | 0.0059 | 0.0059 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0053 | 0.0252 | 0.0252 |
Loa Loa (eye worm) | fibroinase | 0.0078 | 0.0536 | 0.0536 |
Toxoplasma gondii | cathepsin B | 0.0306 | 0.3133 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0078 | 0.0536 | 0.0536 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0078 | 0.0536 | 0.0536 |
Entamoeba histolytica | cysteine protease, putative | 0.0053 | 0.0252 | 0.4706 |
Plasmodium falciparum | serine repeat antigen 5 | 0.0036 | 0.0059 | 0.0556 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0078 | 0.0536 | 0.0536 |
Plasmodium vivax | dipeptidyl aminopeptidase 3, putative | 0.0036 | 0.0059 | 0.0556 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0061 | 0.0342 | 0.0342 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0536 | 0.1551 |
Treponema pallidum | octaprenyl-diphosphate synthase | 0.0031 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0053 | 0.0252 | 0.4706 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0908 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0061 | 0.0342 | 0.0342 |
Loa Loa (eye worm) | cysteine proteinase cathepsin Z | 0.0036 | 0.0059 | 0.0059 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0306 | 0.3133 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0036 | 0.0059 | 0.0059 |
Echinococcus multilocularis | cathepsin b | 0.0908 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0536 | 0.1551 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0078 | 0.0536 | 0.0536 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0536 | 0.1709 |
Trypanosoma brucei | ferric reductase transmembrane protein, putative | 0.0034 | 0.0031 | 0.01 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0306 | 0.3133 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0036 | 0.0059 | 0.0059 |
Leishmania major | cathepsin L-like protease | 0.0078 | 0.0536 | 0.1709 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0078 | 0.0536 | 0.0536 |
Plasmodium vivax | serine-repeat antigen 5 (SERA) | 0.0036 | 0.0059 | 0.0556 |
Mycobacterium tuberculosis | Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) | 0.0124 | 0.1057 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0053 | 0.0252 | 0.0805 |
Onchocerca volvulus | 0.0078 | 0.0536 | 1 | |
Loa Loa (eye worm) | blistered cuticle protein 3 | 0.0072 | 0.047 | 0.047 |
Echinococcus granulosus | cathepsin l1 | 0.0078 | 0.0536 | 0.0536 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0053 | 0.0252 | 0.4706 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0036 | 0.0059 | 0.0059 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0036 | 0.0059 | 0.0059 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0053 | 0.0252 | 0.0805 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0536 | 0.1709 |
Onchocerca volvulus | 0.0061 | 0.0342 | 0.5946 | |
Loa Loa (eye worm) | ctsf protein | 0.0078 | 0.0536 | 0.0536 |
Toxoplasma gondii | cathepsin CPL | 0.0078 | 0.0536 | 0.1709 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0078 | 0.0536 | 0.0536 |
Wolbachia endosymbiont of Brugia malayi | geranylgeranyl pyrophosphate synthase | 0.0031 | 0 | 0.5 |
Plasmodium vivax | vivapain-1 | 0.0053 | 0.0252 | 0.2386 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0036 | 0.0059 | 0.0556 |
Leishmania major | cathepsin L-like protease | 0.0078 | 0.0536 | 0.1709 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0053 | 0.0252 | 0.0252 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0342 | 0.0342 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0078 | 0.0536 | 0.5069 |
Leishmania major | cathepsin L-like protease | 0.0078 | 0.0536 | 0.1709 |
Plasmodium vivax | dipeptidyl aminopeptidase 2, putative | 0.0036 | 0.0059 | 0.0556 |
Entamoeba histolytica | cysteine protease, putative | 0.0036 | 0.0059 | 0.1097 |
Entamoeba histolytica | cysteine protease, putative | 0.0053 | 0.0252 | 0.4706 |
Onchocerca volvulus | 0.0078 | 0.0536 | 1 | |
Onchocerca volvulus | 0.0078 | 0.0536 | 1 | |
Trypanosoma cruzi | farnesyl pyrophosphate synthase, putative | 0.0124 | 0.1057 | 0.1057 |
Plasmodium falciparum | serine repeat antigen 6 | 0.0036 | 0.0059 | 0.0556 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0053 | 0.0252 | 0.4706 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0036 | 0.0059 | 0.0556 |
Leishmania major | cathepsin L-like protease | 0.0078 | 0.0536 | 0.1709 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0908 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0061 | 0.0342 | 0.0922 |
Mycobacterium ulcerans | geranylgeranyl pyrophosphate synthase | 0.0124 | 0.1057 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0536 | 0.1551 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0053 | 0.0252 | 0.0252 |
Entamoeba histolytica | cysteine protease, putative | 0.0036 | 0.0059 | 0.1097 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0036 | 0.0059 | 0.0059 |
Loa Loa (eye worm) | cysteine protease | 0.0078 | 0.0536 | 0.0536 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0536 | 0.1551 |
Echinococcus granulosus | cathepsin b | 0.0908 | 1 | 1 |
Plasmodium falciparum | dipeptidyl aminopeptidase 2 | 0.0036 | 0.0059 | 0.0556 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0078 | 0.0536 | 0.5069 |
Echinococcus granulosus | cysteine protease | 0.0053 | 0.0252 | 0.0252 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0078 | 0.0536 | 0.0536 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0036 | 0.0059 | 0.0556 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0036 | 0.0059 | 0.0059 |
Entamoeba histolytica | cysteine protease, putative | 0.0036 | 0.0059 | 0.1097 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0036 | 0.0059 | 0.1097 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0036 | 0.0059 | 0.0059 |
Plasmodium vivax | vivapain-3 | 0.0053 | 0.0252 | 0.2386 |
Trypanosoma cruzi | ferric reductase transmembrane protein, putative | 0.0034 | 0.0031 | 0.0031 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0036 | 0.0059 | 0.0059 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0536 | 0.1709 |
Toxoplasma gondii | preprocathepsin c precursor, putative | 0.0036 | 0.0059 | 0.0188 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0053 | 0.0252 | 0.0252 |
Schistosoma mansoni | subfamily C1A non-peptidase homologue (C01 family) | 0.0036 | 0.0059 | 0.0059 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0059 | 0.0059 |
Schistosoma mansoni | cathepsin S (C01 family) | 0.0036 | 0.0059 | 0.0059 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0036 | 0.0059 | 0.0059 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0036 | 0.0059 | 0.0059 |
Plasmodium vivax | geranylgeranyl pyrophosphate synthase | 0.0124 | 0.1057 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0306 | 0.3133 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0078 | 0.0536 | 0.5069 |
Brugia malayi | cathepsin L-like precursor | 0.0061 | 0.0342 | 0.0342 |
Echinococcus multilocularis | cathepsin L | 0.0053 | 0.0252 | 0.0252 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0342 | 0.0342 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0536 | 0.1551 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0536 | 0.1551 |
Entamoeba histolytica | cysteine protease, putative | 0.0053 | 0.0252 | 0.4706 |
Entamoeba histolytica | hypothetical protein | 0.0036 | 0.0059 | 0.1097 |
Entamoeba histolytica | cysteine protease, putative | 0.0053 | 0.0252 | 0.4706 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0059 | 0.0059 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0908 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0536 | 0.1709 |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.0536 | 0.0536 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0078 | 0.0536 | 1 |
Giardia lamblia | Farnesyl diphosphate synthase | 0.0124 | 0.1057 | 0.3246 |
Mycobacterium ulcerans | geranylgeranyl pyrophosphate synthase | 0.0124 | 0.1057 | 1 |
Plasmodium vivax | vivapain-2 | 0.0078 | 0.0536 | 0.5069 |
Trypanosoma cruzi | ferric reductase transmembrane protein, putative | 0.0034 | 0.0031 | 0.0031 |
Toxoplasma gondii | cathepsin CPC2 | 0.0036 | 0.0059 | 0.0188 |
Plasmodium vivax | serine-repeat antigen 4 (SERA) | 0.0036 | 0.0059 | 0.0556 |
Loa Loa (eye worm) | polyprenyl synthetase | 0.0124 | 0.1057 | 0.1057 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0342 | 0.0342 |
Onchocerca volvulus | 0.0078 | 0.0536 | 1 | |
Trypanosoma cruzi | farnesyl pyrophosphate synthase | 0.0124 | 0.1057 | 0.1057 |
Wolbachia endosymbiont of Brugia malayi | geranylgeranyl pyrophosphate synthase | 0.0031 | 0 | 0.5 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0908 | 1 | 1 |
Plasmodium falciparum | serine repeat antigen 4 | 0.0036 | 0.0059 | 0.0556 |
Schistosoma mansoni | cathepsin B (C01 family) | 0.0036 | 0.0059 | 0.0059 |
Loa Loa (eye worm) | hypothetical protein | 0.0908 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0059 | 0.0059 |
Brugia malayi | cahepsin L-like non-peptiedase homolog | 0.0036 | 0.0059 | 0.0059 |
Entamoeba histolytica | cysteine protease, putative | 0.0036 | 0.0059 | 0.1097 |
Trichomonas vaginalis | geranylgeranyl pyrophosphate synthase, putative | 0.0124 | 0.1057 | 0.3246 |
Onchocerca volvulus | Cathepsin L homolog | 0.0078 | 0.0536 | 1 |
Trypanosoma cruzi | cysteine protease, putative | 0.0053 | 0.0252 | 0.0252 |
Plasmodium vivax | dipeptidyl aminopeptidase 1, putative | 0.0036 | 0.0059 | 0.0556 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0306 | 0.3133 | 0.3133 |
Onchocerca volvulus | Cathepsin L homolog | 0.0078 | 0.0536 | 1 |
Plasmodium vivax | vivapain-2 | 0.0078 | 0.0536 | 0.5069 |
Trypanosoma brucei | farnesyl pyrophosphate synthase | 0.0124 | 0.1057 | 0.3372 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0536 | 0.0536 |
Plasmodium vivax | serine-repeat antigen 2 (SERA) | 0.0036 | 0.0059 | 0.0556 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0536 | 0.1551 |
Plasmodium falciparum | dipeptidyl aminopeptidase 3 | 0.0036 | 0.0059 | 0.0556 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0536 | 0.1551 |
Entamoeba histolytica | cysteine protease, putative | 0.0053 | 0.0252 | 0.4706 |
Echinococcus granulosus | cathepsin L | 0.0053 | 0.0252 | 0.0252 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0036 | 0.0059 | 0.0059 |
Echinococcus multilocularis | cathepsin b | 0.0908 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0036 | 0.0059 | 0.1097 |
Schistosoma mansoni | dipeptidyl-peptidase I (C01 family) | 0.0036 | 0.0059 | 0.0059 |
Plasmodium vivax | serine-repeat antigen 3 (SERA) | 0.0036 | 0.0059 | 0.0556 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0536 | 0.1709 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0036 | 0.0059 | 0.0059 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0536 | 0.1709 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0536 | 0.1551 |
Entamoeba histolytica | cysteine protease, putative | 0.0053 | 0.0252 | 0.4706 |
Plasmodium vivax | serine-repeat antigen 4 (SERA), putative | 0.0036 | 0.0059 | 0.0556 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0036 | 0.0059 | 0.0059 |
Chlamydia trachomatis | geranylgeranyl pyrophosphate synthase | 0.0031 | 0 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0036 | 0.0059 | 0.1097 |
Echinococcus granulosus | cathepsin b | 0.0908 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0536 | 0.1551 |
Echinococcus multilocularis | cysteine protease | 0.0078 | 0.0536 | 0.0536 |
Toxoplasma gondii | cathepsin CPC1 | 0.0036 | 0.0059 | 0.0188 |
Entamoeba histolytica | cysteine protease, putative | 0.0053 | 0.0252 | 0.4706 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0082 | 0.0082 |
Toxoplasma gondii | polyprenyl synthetase superfamily protein | 0.0124 | 0.1057 | 0.3372 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0078 | 0.0536 | 0.0536 |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.0536 | 0.0536 |
Entamoeba histolytica | cysteine protease, putative | 0.0053 | 0.0252 | 0.4706 |
Schistosoma mansoni | farnesyl pyrophosphate synthase | 0.0124 | 0.1057 | 0.1057 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0036 | 0.0059 | 0.0556 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0536 | 0.1551 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0053 | 0.0252 | 0.0252 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0078 | 0.0536 | 0.1551 |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.0536 | 0.0536 |
Plasmodium falciparum | serine repeat antigen 2 | 0.0036 | 0.0059 | 0.0556 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0053 | 0.0252 | 0.2386 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0536 | 0.1709 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0536 | 0.1551 |
Giardia lamblia | Cathepsin B precursor | 0.0306 | 0.3133 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0061 | 0.0342 | 0.0342 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0036 | 0.0059 | 0.0059 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0536 | 0.1551 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0536 | 0.1551 |
Entamoeba histolytica | cysteine protease, putative | 0.0053 | 0.0252 | 0.4706 |
Leishmania major | cathepsin L-like protease | 0.0078 | 0.0536 | 0.1709 |
Mycobacterium leprae | PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) | 0.0031 | 0 | 0.5 |
Echinococcus granulosus | cathepsin L | 0.0036 | 0.0059 | 0.0059 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0078 | 0.0536 | 0.0536 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0036 | 0.0059 | 0.1097 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0536 | 0.1709 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0053 | 0.0252 | 0.0629 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0536 | 0.1709 |
Onchocerca volvulus | 0.0078 | 0.0536 | 1 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0053 | 0.0252 | 0.4706 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0078 | 0.0536 | 0.1551 |
Echinococcus granulosus | farnesyl pyrophosphate synthase | 0.0124 | 0.1057 | 0.1057 |
Plasmodium falciparum | serine repeat antigen 8 | 0.0036 | 0.0059 | 0.0556 |
Brugia malayi | Cathepsin L-like precursor | 0.0061 | 0.0342 | 0.0342 |
Brugia malayi | Cathepsin L-like precursor | 0.0078 | 0.0536 | 0.0536 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0078 | 0.0536 | 0.0536 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0078 | 0.0536 | 0.0536 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0536 | 0.1709 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0536 | 0.1551 |
Plasmodium vivax | unspecified product | 0.0053 | 0.0252 | 0.2386 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0536 | 0.1551 |
Leishmania major | cathepsin L-like protease | 0.0078 | 0.0536 | 0.1709 |
Plasmodium falciparum | serine repeat antigen 7 | 0.0036 | 0.0059 | 0.0556 |
Brugia malayi | fibroinase precursor | 0.0036 | 0.0059 | 0.0059 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0053 | 0.0252 | 0.0252 |
Trichomonas vaginalis | geranylgeranyl diphosphate synthase, putative | 0.0124 | 0.1057 | 0.3246 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0908 | 1 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0053 | 0.0252 | 0.0252 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0536 | 0.1551 |
Echinococcus multilocularis | farnesyl pyrophosphate synthase | 0.0124 | 0.1057 | 0.1057 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0078 | 0.0536 | 0.0536 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0536 | 0.1551 |
Trichomonas vaginalis | geranylgeranyl pyrophosphate synthase, putative | 0.0124 | 0.1057 | 0.3246 |
Leishmania major | cysteine peptidase A (CPA) | 0.0078 | 0.0536 | 0.1709 |
Echinococcus multilocularis | cysteine protease | 0.0078 | 0.0536 | 0.0536 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0036 | 0.0059 | 0.0059 |
Entamoeba histolytica | cysteine protease, putative | 0.0053 | 0.0252 | 0.4706 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0059 | 0.0059 |
Echinococcus multilocularis | cathepsin L | 0.0036 | 0.0059 | 0.0059 |
Onchocerca volvulus | Dual oxidase homolog | 0.0072 | 0.047 | 0.862 |
Giardia lamblia | Cathepsin B precursor | 0.0306 | 0.3133 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0059 | 0.0059 |
Plasmodium falciparum | serine repeat antigen 1 | 0.0036 | 0.0059 | 0.0556 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0053 | 0.0252 | 0.4706 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0078 | 0.0536 | 0.1551 |
Leishmania major | cathepsin L-like protease | 0.0078 | 0.0536 | 0.1709 |
Loa Loa (eye worm) | cathepsin B | 0.0306 | 0.3133 | 0.3133 |
Plasmodium falciparum | geranylgeranyl pyrophosphate synthase, putative | 0.0124 | 0.1057 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0078 | 0.0536 | 0.1709 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0053 | 0.0252 | 0.0252 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0059 | 0.0059 |
Brugia malayi | Polyprenyl synthetase family protein | 0.0124 | 0.1057 | 0.1057 |
Onchocerca volvulus | 0.0078 | 0.0536 | 1 | |
Plasmodium falciparum | serine repeat antigen 9 | 0.0036 | 0.0059 | 0.0556 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0536 | 0.1551 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0061 | 0.0342 | 0.0342 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0078 | 0.0536 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0053 | 0.0252 | 0.4706 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0036 | 0.0059 | 0.0059 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0078 | 0.0536 | 0.0536 |
Entamoeba histolytica | cysteine protease, putative | 0.0078 | 0.0536 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0061 | 0.0342 | 0.0922 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0053 | 0.0252 | 0.0252 |
Plasmodium falciparum | serine repeat antigen 3 | 0.0036 | 0.0059 | 0.0556 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0536 | 0.1551 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0053 | 0.0252 | 0.4706 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0061 | 0.0342 | 0.6391 |
Giardia lamblia | Cathepsin B precursor | 0.0306 | 0.3133 | 1 |
Plasmodium vivax | unspecified product | 0.0036 | 0.0059 | 0.0556 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0306 | 0.3133 | 0.3133 |
Onchocerca volvulus | 0.0078 | 0.0536 | 1 | |
Leishmania major | ferric reductase, putative | 0.0034 | 0.0031 | 0.01 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0078 | 0.0536 | 0.0536 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0053 | 0.0252 | 0.0252 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0536 | 0.1551 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0053 | 0.0252 | 0.0629 |
Entamoeba histolytica | cysteine protease, putative | 0.0053 | 0.0252 | 0.4706 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0078 | 0.0536 | 0.0536 |
Brugia malayi | Blistered cuticle protein 3 | 0.0072 | 0.047 | 0.047 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0078 | 0.0536 | 0.0536 |
Plasmodium falciparum | dipeptidyl aminopeptidase 1 | 0.0036 | 0.0059 | 0.0556 |
Entamoeba histolytica | cysteine protease, putative | 0.0053 | 0.0252 | 0.4706 |
Onchocerca volvulus | Cathepsin F homolog | 0.0078 | 0.0536 | 1 |
Leishmania major | cathepsin L-like protease | 0.0078 | 0.0536 | 0.1709 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0036 | 0.0059 | 0.0059 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0078 | 0.0536 | 0.1551 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 120.9 uM | In vitro inhibitory concentration against the growth of Toxoplasma gondii in human foreskin fibroblast monolayer cells (HFF cells) | ChEMBL. | 15857119 |
LD50 (functional) | = 260 uM | Lethal dose required to inhibit the growth of human KB (nasopharyngeal carcinoma) cell line | ChEMBL. | 15857119 |
TI (functional) | = 2.15 | Therapeutic index (TI) value as ratio of lethal dose (LD50) to the inhibitory concentration (IC50) | ChEMBL. | 15857119 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.