Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | cysteine protease, putative | 0.0244 | 0.1238 | 0.2088 |
Plasmodium vivax | unspecified product | 0.0346 | 0.1784 | 0.1197 |
Echinococcus multilocularis | serine:threonine protein kinase:endoribonuclease | 0.0022 | 0.0051 | 0.0051 |
Giardia lamblia | Cathepsin B precursor | 0.0244 | 0.1238 | 0.3135 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0244 | 0.1238 | 0.2133 |
Entamoeba histolytica | cysteine protease, putative | 0.059 | 0.3088 | 0.5296 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0244 | 0.1238 | 0.1238 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0346 | 0.1784 | 0.1784 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1098 | 0.5802 | 1 |
Echinococcus granulosus | cathepsin L | 0.0244 | 0.1238 | 0.1238 |
Echinococcus granulosus | cathepsin b | 0.1884 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0751 | 0.3948 | 0.3948 |
Brugia malayi | cathepsin L-like cysteine proteinase | 0.0244 | 0.1238 | 0.1238 |
Giardia lamblia | Cathepsin L precursor | 0.0244 | 0.1238 | 0.3135 |
Loa Loa (eye worm) | hypothetical protein | 0.0346 | 0.1784 | 0.1742 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1098 | 0.5802 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0244 | 0.1238 | 0.3135 |
Giardia lamblia | Cysteine protease | 0.0244 | 0.1238 | 0.3135 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1098 | 0.5802 | 0.5802 |
Giardia lamblia | Cathepsin B precursor | 0.0751 | 0.3948 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0013 | 0.0001 | 0.0001 |
Loa Loa (eye worm) | hypothetical protein | 0.0346 | 0.1784 | 0.1742 |
Entamoeba histolytica | cysteine protease, putative | 0.059 | 0.3088 | 0.5296 |
Echinococcus multilocularis | cathepsin L | 0.059 | 0.3088 | 0.3088 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.1098 | 0.5802 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1098 | 0.5802 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin F-like cysteine peptidase | 0.0244 | 0.1238 | 0.2133 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase | 0.0244 | 0.1238 | 0.2133 |
Schistosoma mansoni | cathepsin S (C01 family) | 0.0244 | 0.1238 | 0.1238 |
Giardia lamblia | Cathepsin B precursor | 0.0244 | 0.1238 | 0.3135 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0244 | 0.1238 | 0.1238 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0244 | 0.1238 | 0.1238 |
Entamoeba histolytica | cysteine protease, putative | 0.0244 | 0.1238 | 0.2088 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0244 | 0.1238 | 0.2088 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0244 | 0.1238 | 0.3135 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1098 | 0.5802 | 1 |
Schistosoma mansoni | subfamily C1A non-peptidase homologue (C01 family) | 0.0244 | 0.1238 | 0.1238 |
Plasmodium vivax | vivapain-2 | 0.1098 | 0.5802 | 1 |
Entamoeba histolytica | cysteine proteinase 2 | 0.059 | 0.3088 | 0.5296 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1098 | 0.5802 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1098 | 0.5802 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1884 | 1 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0752 | 0.3951 | 0.3951 |
Onchocerca volvulus | 0.1098 | 0.5802 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1098 | 0.5802 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1098 | 0.5802 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.1098 | 0.5802 | 0.5802 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0244 | 0.1238 | 0.3135 |
Onchocerca volvulus | Cathepsin L homolog | 0.1098 | 0.5802 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0244 | 0.1238 | 0.2133 |
Echinococcus granulosus | serine:threonine protein kinase:endoribonuclease | 0.0022 | 0.0051 | 0.0051 |
Entamoeba histolytica | cysteine protease, putative | 0.059 | 0.3088 | 0.5296 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.1098 | 0.5802 | 0.578 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0244 | 0.1238 | 0.1238 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1098 | 0.5802 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.1098 | 0.5802 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1098 | 0.5802 | 1 |
Mycobacterium tuberculosis | Possible maturase | 0.0012 | 0 | 0.5 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.1098 | 0.5802 | 0.578 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0022 | 0.0051 | 0.0051 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1884 | 1 | 1 |
Echinococcus multilocularis | cathepsin L | 0.0244 | 0.1238 | 0.1238 |
Entamoeba histolytica | cysteine protease, putative | 0.0244 | 0.1238 | 0.2088 |
Echinococcus granulosus | cathepsin b | 0.1884 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0244 | 0.1238 | 0.1238 |
Giardia lamblia | Hypothetical protein | 0.0244 | 0.1238 | 0.3135 |
Giardia lamblia | Hypothetical protein | 0.0244 | 0.1238 | 0.3135 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1098 | 0.5802 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0244 | 0.1238 | 0.1193 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin H-like cysteine peptidase | 0.0244 | 0.1238 | 0.2133 |
Leishmania major | cathepsin L-like protease | 0.1098 | 0.5802 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1098 | 0.5802 | 0.5802 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0244 | 0.1238 | 0.1238 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.059 | 0.3088 | 0.3088 |
Giardia lamblia | Cathepsin L precursor | 0.0244 | 0.1238 | 0.3135 |
Plasmodium vivax | vivapain-1 | 0.059 | 0.3088 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1098 | 0.5802 | 1 |
Echinococcus multilocularis | cathepsin b | 0.1884 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.059 | 0.3088 | 0.5296 |
Schistosoma mansoni | cathepsin B (C01 family) | 0.0244 | 0.1238 | 0.1238 |
Onchocerca volvulus | 0.1098 | 0.5802 | 1 | |
Brugia malayi | fibroinase precursor | 0.0244 | 0.1238 | 0.1238 |
Loa Loa (eye worm) | cathepsin B | 0.0751 | 0.3948 | 0.3917 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1098 | 0.5802 | 0.5802 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0752 | 0.3951 | 0.6793 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.059 | 0.3088 | 0.3088 |
Giardia lamblia | Cathepsin L precursor | 0.0244 | 0.1238 | 0.3135 |
Giardia lamblia | Cysteine protease | 0.0244 | 0.1238 | 0.3135 |
Entamoeba histolytica | cysteine proteinase, putative | 0.059 | 0.3088 | 0.5296 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1098 | 0.5802 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1098 | 0.5802 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1098 | 0.5802 | 0.5802 |
Schistosoma mansoni | dipeptidyl-peptidase I (C01 family) | 0.0244 | 0.1238 | 0.1238 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1098 | 0.5802 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1098 | 0.5802 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1098 | 0.5802 | 1 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.059 | 0.3088 | 0.3088 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0019 | 0.0033 | 0.0033 |
Entamoeba histolytica | cysteine protease, putative | 0.059 | 0.3088 | 0.5296 |
Leishmania major | cathepsin L-like protease | 0.1098 | 0.5802 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.059 | 0.3088 | 0.5296 |
Entamoeba histolytica | cysteine protease, putative | 0.0244 | 0.1238 | 0.2088 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1884 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1098 | 0.5802 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1098 | 0.5802 | 0.578 |
Brugia malayi | cathepsin L-like precursor | 0.0752 | 0.3951 | 0.3951 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0244 | 0.1238 | 0.3135 |
Plasmodium vivax | vivapain-2 | 0.1098 | 0.5802 | 1 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0244 | 0.1238 | 0.2088 |
Brugia malayi | Ribonuclease 2-5A family protein | 0.0022 | 0.0051 | 0.0051 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0751 | 0.3948 | 0.3948 |
Loa Loa (eye worm) | hypothetical protein | 0.0244 | 0.1238 | 0.1193 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0752 | 0.3951 | 0.6811 |
Schistosoma mansoni | cathepsin s | 0.0346 | 0.1784 | 0.1784 |
Brugia malayi | cathepsin L precursor | 0.0244 | 0.1238 | 0.1238 |
Plasmodium vivax | unspecified product | 0.059 | 0.3088 | 0.4054 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1098 | 0.5802 | 0.5802 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0752 | 0.3951 | 0.6811 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0244 | 0.1238 | 0.2133 |
Giardia lamblia | Cathepsin B precursor | 0.0244 | 0.1238 | 0.3135 |
Entamoeba histolytica | cysteine protease, putative | 0.059 | 0.3088 | 0.5296 |
Loa Loa (eye worm) | hypothetical protein | 0.0752 | 0.3951 | 0.392 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0019 | 0.0033 | 0.0033 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.059 | 0.3088 | 0.5322 |
Brugia malayi | Cathepsin L-like precursor | 0.1098 | 0.5802 | 0.5802 |
Entamoeba histolytica | cysteine proteinase, putative | 0.059 | 0.3088 | 0.5296 |
Giardia lamblia | Cathepsin L precursor | 0.0244 | 0.1238 | 0.3135 |
Brugia malayi | Cathepsin L-like precursor | 0.0752 | 0.3951 | 0.3951 |
Echinococcus granulosus | cathepsin l1 | 0.1098 | 0.5802 | 0.5802 |
Plasmodium vivax | vivapain-3 | 0.059 | 0.3088 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1098 | 0.5802 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0346 | 0.1784 | 0.1784 |
Giardia lamblia | Cysteine protease | 0.0244 | 0.1238 | 0.3135 |
Giardia lamblia | Cathepsin L-like protease | 0.0244 | 0.1238 | 0.3135 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.1098 | 0.5802 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0244 | 0.1238 | 0.2133 |
Entamoeba histolytica | cysteine protease, putative | 0.0244 | 0.1238 | 0.2088 |
Trypanosoma cruzi | cysteine protease, putative | 0.059 | 0.3088 | 0.3088 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1098 | 0.5802 | 0.5802 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1098 | 0.5802 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0244 | 0.1238 | 0.2133 |
Brugia malayi | Cathepsin L-like precursor | 0.1098 | 0.5802 | 0.5802 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.059 | 0.3088 | 0.3088 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0244 | 0.1238 | 0.1238 |
Giardia lamblia | Cathepsin B precursor | 0.0751 | 0.3948 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1884 | 1 | 1 |
Trichomonas vaginalis | serine threonine-protein kinase, putative | 0.0022 | 0.005 | 0.0087 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.059 | 0.3088 | 0.3088 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1098 | 0.5802 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.1098 | 0.5802 | 0.5802 |
Loa Loa (eye worm) | hypothetical protein | 0.0752 | 0.3951 | 0.392 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1098 | 0.5802 | 0.5802 |
Toxoplasma gondii | cathepsin CPL | 0.1098 | 0.5802 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.059 | 0.3088 | 0.5296 |
Loa Loa (eye worm) | ctsf protein | 0.1098 | 0.5802 | 0.578 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0244 | 0.1238 | 0.1238 |
Loa Loa (eye worm) | hypothetical protein | 0.0244 | 0.1238 | 0.1193 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0244 | 0.1238 | 0.2133 |
Entamoeba histolytica | cysteine proteinase, putative | 0.059 | 0.3088 | 0.5296 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1098 | 0.5802 | 0.5802 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1884 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0751 | 0.3948 | 0.6804 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1098 | 0.5802 | 0.5802 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1098 | 0.5802 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.1098 | 0.5802 | 0.578 |
Entamoeba histolytica | cysteine protease, putative | 0.059 | 0.3088 | 0.5296 |
Loa Loa (eye worm) | cysteine proteinase cathepsin Z | 0.0244 | 0.1238 | 0.1193 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1098 | 0.5802 | 0.5802 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.1098 | 0.5802 | 0.5802 |
Loa Loa (eye worm) | hypothetical protein | 0.0244 | 0.1238 | 0.1193 |
Leishmania major | cysteine peptidase A (CPA) | 0.1098 | 0.5802 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0346 | 0.1784 | 0.1784 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0244 | 0.1238 | 0.2133 |
Onchocerca volvulus | 0.1098 | 0.5802 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.059 | 0.3088 | 0.5322 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0244 | 0.1238 | 0.1238 |
Onchocerca volvulus | 0.0244 | 0.1238 | 0.2133 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0244 | 0.1238 | 0.2133 |
Onchocerca volvulus | Cathepsin L homolog | 0.0244 | 0.1238 | 0.2133 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1098 | 0.5802 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0244 | 0.1238 | 0.2133 |
Brugia malayi | Cathepsin L-like precursor | 0.1098 | 0.5802 | 0.5802 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0346 | 0.1784 | 0.1742 |
Entamoeba histolytica | cysteine protease, putative | 0.059 | 0.3088 | 0.5296 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1098 | 0.5802 | 1 |
Echinococcus multilocularis | cysteine protease | 0.1098 | 0.5802 | 0.5802 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0244 | 0.1238 | 0.1238 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.059 | 0.3088 | 0.3088 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1098 | 0.5802 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0244 | 0.1238 | 0.2133 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0244 | 0.1238 | 0.2133 |
Leishmania major | cathepsin L-like protease | 0.1098 | 0.5802 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0019 | 0.0033 | 0.0033 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.059 | 0.3088 | 0.4054 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1098 | 0.5802 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0346 | 0.1784 | 0.1742 |
Echinococcus granulosus | cathepsin L | 0.059 | 0.3088 | 0.3088 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0244 | 0.1238 | 0.2133 |
Leishmania major | cathepsin L-like protease | 0.1098 | 0.5802 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.059 | 0.3088 | 0.5322 |
Entamoeba histolytica | cysteine proteinase, putative | 0.059 | 0.3088 | 0.5296 |
Loa Loa (eye worm) | hypothetical protein | 0.0244 | 0.1238 | 0.1193 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.059 | 0.3088 | 0.3088 |
Giardia lamblia | Cathepsin B precursor | 0.0751 | 0.3948 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1098 | 0.5802 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0244 | 0.1238 | 0.1238 |
Onchocerca volvulus | Cathepsin F homolog | 0.1098 | 0.5802 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1098 | 0.5802 | 0.5802 |
Onchocerca volvulus | Cathepsin L homolog | 0.1098 | 0.5802 | 1 |
Giardia lamblia | Cathepsin L precursor | 0.0244 | 0.1238 | 0.3135 |
Echinococcus granulosus | cysteine protease | 0.059 | 0.3088 | 0.3088 |
Brugia malayi | hypothetical protein | 0.0019 | 0.0033 | 0.0033 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0019 | 0.0033 | 0.0033 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1098 | 0.5802 | 1 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0346 | 0.1784 | 0.1784 |
Giardia lamblia | Cathepsin L precursor | 0.0244 | 0.1238 | 0.3135 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.1884 | 1 | 1 |
Giardia lamblia | Cysteine protease | 0.0244 | 0.1238 | 0.3135 |
Giardia lamblia | Cathepsin B-like cysteine proteinase 3 precursor | 0.0244 | 0.1238 | 0.3135 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.059 | 0.3088 | 0.5296 |
Entamoeba histolytica | cysteine protease, putative | 0.0244 | 0.1238 | 0.2088 |
Toxoplasma gondii | cathepsin B | 0.0751 | 0.3948 | 0.5938 |
Schistosoma mansoni | cathepsin C | 0.0244 | 0.1238 | 0.1238 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1098 | 0.5802 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1098 | 0.5802 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0022 | 0.005 | 0.0087 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0244 | 0.1238 | 0.1238 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1098 | 0.5802 | 1 |
Giardia lamblia | Cathepsin L-like protease | 0.0244 | 0.1238 | 0.3135 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1098 | 0.5802 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.059 | 0.3088 | 0.3088 |
Brugia malayi | Cathepsin L-like precursor | 0.1098 | 0.5802 | 0.5802 |
Entamoeba histolytica | cysteine protease, putative | 0.1098 | 0.5802 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0752 | 0.3951 | 0.3951 |
Loa Loa (eye worm) | hypothetical protein | 0.0244 | 0.1238 | 0.1193 |
Onchocerca volvulus | 0.1098 | 0.5802 | 1 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0244 | 0.1238 | 0.1238 |
Loa Loa (eye worm) | hypothetical protein | 0.0244 | 0.1238 | 0.1193 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0244 | 0.1238 | 0.1238 |
Entamoeba histolytica | protein kinase, putative | 0.0022 | 0.0051 | 0.0032 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0244 | 0.1238 | 0.2133 |
Echinococcus multilocularis | cathepsin b | 0.1884 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.1098 | 0.5802 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1098 | 0.5802 | 1 |
Brugia malayi | cahepsin L-like non-peptiedase homolog | 0.0244 | 0.1238 | 0.1238 |
Schistosoma mansoni | hypothetical protein | 0.0548 | 0.2862 | 0.2862 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0244 | 0.1238 | 0.2133 |
Loa Loa (eye worm) | fibroinase | 0.1098 | 0.5802 | 0.578 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1098 | 0.5802 | 0.5802 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0244 | 0.1238 | 0.1193 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0751 | 0.3948 | 0.6804 |
Entamoeba histolytica | protein kinase, putative | 0.0022 | 0.0051 | 0.0032 |
Leishmania major | cathepsin L-like protease | 0.1098 | 0.5802 | 1 |
Giardia lamblia | Encystation-specific protease | 0.0244 | 0.1238 | 0.3135 |
Giardia lamblia | Cathepsin B precursor | 0.0244 | 0.1238 | 0.3135 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0752 | 0.3951 | 0.3951 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0244 | 0.1238 | 0.1238 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1098 | 0.5802 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.059 | 0.3088 | 0.5296 |
Leishmania major | cathepsin L-like protease | 0.1098 | 0.5802 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.059 | 0.3088 | 0.5296 |
Brugia malayi | Cathepsin L-like precursor | 0.0752 | 0.3951 | 0.3951 |
Trypanosoma brucei | RNA helicase, putative | 0.0548 | 0.2862 | 0.4933 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0244 | 0.1238 | 0.2133 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1098 | 0.5802 | 1 |
Echinococcus multilocularis | cysteine protease | 0.1098 | 0.5802 | 0.5802 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.059 | 0.3088 | 0.5322 |
Entamoeba histolytica | hypothetical protein | 0.0244 | 0.1238 | 0.2088 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or H-like cysteine peptidase | 0.0244 | 0.1238 | 0.2133 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.059 | 0.3088 | 0.3088 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0752 | 0.3951 | 0.3951 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1098 | 0.5802 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1098 | 0.5802 | 0.5802 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1098 | 0.5802 | 1 |
Onchocerca volvulus | 0.1098 | 0.5802 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1098 | 0.5802 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0346 | 0.1784 | 0.1784 |
Loa Loa (eye worm) | hypothetical protein | 0.0752 | 0.3951 | 0.392 |
Entamoeba histolytica | cysteine protease, putative | 0.059 | 0.3088 | 0.5296 |
Onchocerca volvulus | 0.0752 | 0.3951 | 0.6811 | |
Leishmania major | cathepsin L-like protease | 0.1098 | 0.5802 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.059 | 0.3088 | 0.3088 |
Onchocerca volvulus | 0.1098 | 0.5802 | 1 | |
Onchocerca volvulus | 0.1098 | 0.5802 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | = 0.19 mg kg-1 | Effective dose of compound against Streptococcus aureus Smith (GC 4543) in mice | ChEMBL. | 15214775 |
ED50 (functional) | = 0.39 mg kg-1 | Effective dose of compound against Enterococcus faecalis (GC 6189) in mice | ChEMBL. | 15214775 |
MIC (functional) | <= 0.25 ug ml-1 | In vitro minimum inhibitory concentration of the compound against Streptococcus species; Range is 0.12-0.25 ug/mL | ChEMBL. | 15214775 |
MIC (functional) | = 2 ug ml-1 | In vitro minimum inhibitory concentration of the compound against Staphylococcus species; Range is 0.5-2 ug/mL | ChEMBL. | 15214775 |
MIC (functional) | = 4 ug ml-1 | In vitro minimum inhibitory concentration of the compound against Enterococcus species; Range is 2-4 ug/mL | ChEMBL. | 15214775 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.