Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | Cathepsin B precursor | 0.0053 | 0.2688 | 1 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | myosin xvIII | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0029 | 0.086 | 0.086 |
Echinococcus granulosus | g-protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | G-protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.086 | 0.0722 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | cathepsin L-like precursor | 0.0021 | 0.0274 | 0.0274 |
Echinococcus granulosus | neuropeptide s receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | fibroinase | 0.0029 | 0.086 | 0.0722 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0029 | 0.086 | 1 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Echinococcus multilocularis | cathepsin b | 0.0153 | 1 | 1 |
Brugia malayi | GnHR receptor homolog | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Echinococcus granulosus | neuropeptides capa receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | neuropeptide F receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | amine GPCR | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0051 | 0.2513 | 0.2513 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0149 | 0.5 |
Onchocerca volvulus | Cathepsin L homolog | 0.0029 | 0.086 | 0.2619 |
Echinococcus granulosus | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0029 | 0.086 | 1 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Echinococcus granulosus | somatostatin receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Serotonin receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | allatostatin A receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Schistosoma mansoni | hypothetical protein | 0.0138 | 0.8886 | 0.8886 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0029 | 0.086 | 0.086 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0153 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0153 | 1 | 1 |
Schistosoma mansoni | biogenic amine receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | amine GPCR | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0029 | 0.086 | 0.086 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0053 | 0.2688 | 0.2688 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | orexin receptor type 2 | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0029 | 0.086 | 0.086 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0053 | 0.2688 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0021 | 0.0274 | 0.3182 |
Brugia malayi | RE15519p | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | cysteine protease | 0.0029 | 0.086 | 0.086 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0149 | 0.5 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | serotonin receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Dopamine receptor protein 2 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | cathepsin b | 0.0153 | 1 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Echinococcus multilocularis | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | Dopamine receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | RNA helicase, putative | 0.0138 | 0.8886 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | sex peptide receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | G protein-coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0153 | 1 | 1 |
Brugia malayi | ORL1-like opioid receptor | 0.0051 | 0.2513 | 0.2513 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0053 | 0.2688 | 1 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0051 | 0.2513 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Brugia malayi | sulfakinin receptor protein | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0029 | 0.086 | 0.0722 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0029 | 0.086 | 0.086 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0051 | 0.2513 | 0.2513 |
Toxoplasma gondii | cathepsin B | 0.0053 | 0.2688 | 1 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0.0149 | 0.1732 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0149 | 0.0149 |
Schistosoma mansoni | amine GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0051 | 0.2513 | 0.24 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Loa Loa (eye worm) | cysteine protease | 0.0029 | 0.086 | 0.0722 |
Schistosoma mansoni | biogenic amine receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | Dopamine receptor protein 1 | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus multilocularis | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0153 | 1 | 1 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Cathepsin L-like precursor | 0.0021 | 0.0274 | 0.0274 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0021 | 0.0274 | 0.0274 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0021 | 0.0274 | 0.0274 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0274 | 0.0127 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Schistosoma mansoni | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Brugia malayi | Melatonin receptor type 1A | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | serotonin receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0149 | 0.1732 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0029 | 0.086 | 1 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0149 | 0.0149 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0149 | 0.0149 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0053 | 0.2688 | 0.2688 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0149 | 0.0554 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0274 | 0.0127 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0149 | 0.0149 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0029 | 0.086 | 0.086 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0021 | 0.0274 | 0.0274 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0053 | 0.2688 | 0.3024 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus granulosus | serotonin receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Loa Loa (eye worm) | ctsf protein | 0.0029 | 0.086 | 0.0722 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0149 | 0.0149 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0149 | 0.0168 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | biogenic amine receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | opsin-like receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | somatostatin receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0153 | 1 | 1 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | opsin-like receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Echinococcus granulosus | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0149 | 0.0149 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0029 | 0.086 | 0.086 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0029 | 0.086 | 0.0722 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Echinococcus granulosus | cathepsin l1 | 0.0021 | 0.0274 | 0.0274 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0149 | 0.0149 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | amine GPCR | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | cathepsin B | 0.0053 | 0.2688 | 0.2577 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Giardia lamblia | Cathepsin B precursor | 0.0053 | 0.2688 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Plasmodium vivax | vivapain-2 | 0.0029 | 0.086 | 1 |
Brugia malayi | G-protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | adenoreceptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0029 | 0.086 | 0.086 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0051 | 0.2513 | 0.2513 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0149 | 0.5 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0051 | 0.2513 | 0.24 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0149 | 0.0554 |
Schistosoma mansoni | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | neuropeptide F receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0051 | 0.2513 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0153 | 1 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | AKH receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0029 | 0.086 | 0.086 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | Cathepsin L homolog | 0.0029 | 0.086 | 0.2619 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0021 | 0.0274 | 0.1018 |
Echinococcus granulosus | cathepsin b | 0.0153 | 1 | 1 |
Brugia malayi | Serotonin receptor | 0.0051 | 0.2513 | 0.2513 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0149 | 0.5 |
Schistosoma mansoni | amine GPCR | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0051 | 0.2513 | 0.2513 |
Plasmodium vivax | vivapain-2 | 0.0029 | 0.086 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0029 | 0.086 | 0.086 |
Brugia malayi | putative neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0029 | 0.086 | 0.086 |
Brugia malayi | larval opioid receptor | 0.0051 | 0.2513 | 0.2513 |
Toxoplasma gondii | cathepsin CPL | 0.0029 | 0.086 | 0.2802 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0274 | 0.0127 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0029 | 0.086 | 0.086 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0029 | 0.086 | 1 |
Echinococcus granulosus | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Leishmania major | cysteine peptidase A (CPA) | 0.0029 | 0.086 | 0.2802 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0029 | 0.086 | 0.086 |
Schistosoma mansoni | histamine h1 receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0051 | 0.2513 | 0.2513 |
Entamoeba histolytica | cysteine protease, putative | 0.0029 | 0.086 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus multilocularis | fmrfamide receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0029 | 0.086 | 0.086 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | sex peptide receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | cysteine protease | 0.0029 | 0.086 | 0.086 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | cathepsin l1 | 0.0029 | 0.086 | 0.086 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | Cathepsin F homolog | 0.0029 | 0.086 | 0.2619 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Cathepsin L-like precursor | 0.0021 | 0.0274 | 0.0274 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0051 | 0.2513 | 0.2513 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0149 | 0.1732 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | fmrfamide receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | opsin-like receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | allatostatin A receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | fmrfamide receptor | 0.0051 | 0.2513 | 0.2513 |
Giardia lamblia | Cathepsin B precursor | 0.0053 | 0.2688 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0029 | 0.086 | 1 |
Brugia malayi | follicle stimulating hormone receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0021 | 0.0274 | 0.1018 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 2 % | The concentration to inhibit cell proliferation of PC3 human tumour cell lines using the sulforhodamine B assay | ChEMBL. | 9341910 |
Inhibition (functional) | = 3 % | The concentration to inhibit colony formation of PC3 human tumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 4 % | The concentration to inhibit colony formation of MCF-7 human tumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 6 % | The concentration to inhibit colony formation of Ishikawa human tumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 8 % | The concentration to inhibit cell proliferation of MCF-7 human tumour cell lines using the sulforhodamine B assay | ChEMBL. | 9341910 |
Inhibition (functional) | = 8 % | The concentration to inhibit cell proliferation of MDA-MB-231 human tumour cell lines using the sulforhodamine B assay | ChEMBL. | 9341910 |
Inhibition (functional) | = 15 % | The concentration to inhibit colony formation of MDA-MB-231 human tumour cell lines | ChEMBL. | 9341910 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.