Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0095 | 0.1474 | 0.5 | |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0095 | 0.1474 | 0.5 |
Brugia malayi | putative neuropeptide receptor | 0.0095 | 0.1474 | 1 |
Mycobacterium leprae | POSSIBLE PENICILLIN-BINDING LIPOPROTEIN | 0.0371 | 0.9844 | 1 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0095 | 0.1474 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0095 | 0.1474 | 0.5 |
Brugia malayi | neuropeptide F receptor | 0.0095 | 0.1474 | 1 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0095 | 0.1474 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0095 | 0.1474 | 0.5 |
Onchocerca volvulus | 0.0095 | 0.1474 | 0.5 | |
Echinococcus multilocularis | g protein coupled receptor | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0095 | 0.1474 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Brugia malayi | hypothetical protein | 0.0095 | 0.1474 | 1 |
Onchocerca volvulus | 0.0095 | 0.1474 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0095 | 0.1474 | 0.5 |
Schistosoma mansoni | biogenic amine receptor | 0.0095 | 0.1474 | 0.5 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0095 | 0.1474 | 0.5 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0095 | 0.1474 | 0.5 |
Brugia malayi | ORL1-like opioid receptor | 0.0095 | 0.1474 | 1 |
Wolbachia endosymbiont of Brugia malayi | cell division protein FtsI | 0.0376 | 1 | 0.5 |
Brugia malayi | hypothetical protein | 0.0095 | 0.1474 | 1 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0095 | 0.1474 | 1 |
Echinococcus granulosus | sex peptide receptor | 0.0095 | 0.1474 | 0.5 |
Onchocerca volvulus | 0.0095 | 0.1474 | 0.5 | |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0095 | 0.1474 | 0.5 |
Brugia malayi | Serotonin receptor | 0.0095 | 0.1474 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0095 | 0.1474 | 0.5 |
Mycobacterium ulcerans | penicillin-binding lipoprotein | 0.0371 | 0.9844 | 1 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0095 | 0.1474 | 0.5 |
Brugia malayi | neuropeptide F receptor | 0.0095 | 0.1474 | 1 |
Brugia malayi | Serotonin receptor | 0.0095 | 0.1474 | 1 |
Brugia malayi | Dopamine receptor | 0.0095 | 0.1474 | 1 |
Brugia malayi | hypothetical protein | 0.0095 | 0.1474 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0095 | 0.1474 | 0.5 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0095 | 0.1474 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0095 | 0.1474 | 0.5 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0095 | 0.1474 | 0.5 |
Echinococcus granulosus | hypothetical protein | 0.0095 | 0.1474 | 0.5 |
Schistosoma mansoni | adenoreceptor | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0095 | 0.1474 | 0.5 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0095 | 0.1474 | 0.5 |
Onchocerca volvulus | 0.0095 | 0.1474 | 0.5 | |
Echinococcus multilocularis | orexin receptor type 2 | 0.0095 | 0.1474 | 0.5 |
Brugia malayi | G protein-coupled receptor | 0.0095 | 0.1474 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0095 | 0.1474 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0095 | 0.1474 | 0.5 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0095 | 0.1474 | 0.5 |
Echinococcus granulosus | neuropeptide receptor | 0.0095 | 0.1474 | 0.5 |
Echinococcus granulosus | neuropeptide s receptor | 0.0095 | 0.1474 | 0.5 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0095 | 0.1474 | 0.5 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0095 | 0.1474 | 0.5 |
Brugia malayi | hypothetical protein | 0.0095 | 0.1474 | 1 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0095 | 0.1474 | 0.5 |
Brugia malayi | follicle stimulating hormone receptor | 0.0095 | 0.1474 | 1 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0095 | 0.1474 | 0.5 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0095 | 0.1474 | 0.5 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0095 | 0.1474 | 0.5 |
Brugia malayi | RE15519p | 0.0095 | 0.1474 | 1 |
Echinococcus multilocularis | fmrfamide receptor | 0.0095 | 0.1474 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0095 | 0.1474 | 0.5 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Brugia malayi | hypothetical protein | 0.0095 | 0.1474 | 1 |
Schistosoma mansoni | amine GPCR | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0095 | 0.1474 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0095 | 0.1474 | 0.5 |
Echinococcus multilocularis | g protein coupled receptor | 0.0095 | 0.1474 | 0.5 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0095 | 0.1474 | 0.5 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0095 | 0.1474 | 0.5 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0095 | 0.1474 | 1 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0095 | 0.1474 | 0.5 |
Onchocerca volvulus | 0.0095 | 0.1474 | 0.5 | |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0095 | 0.1474 | 0.5 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0095 | 0.1474 | 0.5 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0095 | 0.1474 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0095 | 0.1474 | 0.5 |
Echinococcus granulosus | orexin receptor type 2 | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Schistosoma mansoni | biogenic amine receptor | 0.0095 | 0.1474 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0095 | 0.1474 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0095 | 0.1474 | 0.5 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0095 | 0.1474 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Schistosoma mansoni | histamine h1 receptor | 0.0095 | 0.1474 | 0.5 |
Echinococcus granulosus | fmrfamide receptor | 0.0095 | 0.1474 | 0.5 |
Brugia malayi | Dopamine receptor protein 1 | 0.0095 | 0.1474 | 1 |
Onchocerca volvulus | 0.0095 | 0.1474 | 0.5 | |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0095 | 0.1474 | 0.5 |
Echinococcus multilocularis | fmrfamide receptor | 0.0095 | 0.1474 | 0.5 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0095 | 0.1474 | 1 |
Brugia malayi | G-protein coupled receptor | 0.0095 | 0.1474 | 1 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0095 | 0.1474 | 0.5 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0095 | 0.1474 | 1 |
Echinococcus granulosus | allatostatin A receptor | 0.0095 | 0.1474 | 0.5 |
Schistosoma mansoni | opsin-like receptor | 0.0095 | 0.1474 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Echinococcus granulosus | somatostatin receptor | 0.0095 | 0.1474 | 0.5 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0095 | 0.1474 | 0.5 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0095 | 0.1474 | 0.5 |
Brugia malayi | hypothetical protein | 0.0095 | 0.1474 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0095 | 0.1474 | 0.5 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0095 | 0.1474 | 1 |
Echinococcus granulosus | g-protein coupled receptor | 0.0095 | 0.1474 | 0.5 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0095 | 0.1474 | 0.5 |
Schistosoma mansoni | neuropeptide receptor | 0.0095 | 0.1474 | 0.5 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0095 | 0.1474 | 0.5 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0095 | 0.1474 | 0.5 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0095 | 0.1474 | 0.5 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0095 | 0.1474 | 0.5 |
Schistosoma mansoni | biogenic amine receptor | 0.0095 | 0.1474 | 0.5 |
Echinococcus multilocularis | g protein coupled receptor | 0.0095 | 0.1474 | 0.5 |
Echinococcus granulosus | neuropeptide receptor | 0.0095 | 0.1474 | 0.5 |
Schistosoma mansoni | amine GPCR | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Brugia malayi | hypothetical protein | 0.0095 | 0.1474 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding lipoprotein | 0.0371 | 0.9844 | 1 |
Onchocerca volvulus | 0.0095 | 0.1474 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0095 | 0.1474 | 0.5 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0095 | 0.1474 | 0.5 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0095 | 0.1474 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0095 | 0.1474 | 0.5 |
Onchocerca volvulus | 0.0095 | 0.1474 | 0.5 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Treponema pallidum | penicillin-binding protein (pbp-1) | 0.0376 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0095 | 0.1474 | 1 |
Brugia malayi | larval opioid receptor | 0.0095 | 0.1474 | 1 |
Echinococcus multilocularis | somatostatin receptor | 0.0095 | 0.1474 | 0.5 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0095 | 0.1474 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0095 | 0.1474 | 0.5 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0095 | 0.1474 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0095 | 0.1474 | 0.5 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0095 | 0.1474 | 0.5 |
Brugia malayi | hypothetical protein | 0.0095 | 0.1474 | 1 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0095 | 0.1474 | 1 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0095 | 0.1474 | 0.5 |
Schistosoma mansoni | opsin-like receptor | 0.0095 | 0.1474 | 0.5 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0095 | 0.1474 | 0.5 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0095 | 0.1474 | 0.5 |
Onchocerca volvulus | 0.0095 | 0.1474 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Onchocerca volvulus | 0.0095 | 0.1474 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0095 | 0.1474 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0095 | 0.1474 | 0.5 |
Echinococcus granulosus | g protein coupled receptor | 0.0095 | 0.1474 | 0.5 |
Brugia malayi | Dopamine receptor protein 2 | 0.0095 | 0.1474 | 1 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Echinococcus multilocularis | sex peptide receptor | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0095 | 0.1474 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0095 | 0.1474 | 0.5 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0095 | 0.1474 | 0.5 |
Onchocerca volvulus | 0.0095 | 0.1474 | 0.5 | |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0095 | 0.1474 | 0.5 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Brugia malayi | sulfakinin receptor protein | 0.0095 | 0.1474 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Echinococcus granulosus | serotonin receptor | 0.0095 | 0.1474 | 0.5 |
Onchocerca volvulus | 0.0095 | 0.1474 | 0.5 | |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0095 | 0.1474 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Echinococcus multilocularis | neuropeptide receptor | 0.0095 | 0.1474 | 0.5 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Brugia malayi | hypothetical protein | 0.0095 | 0.1474 | 1 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0095 | 0.1474 | 0.5 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0095 | 0.1474 | 0.5 |
Schistosoma mansoni | neuropeptide receptor | 0.0095 | 0.1474 | 0.5 |
Brugia malayi | Melatonin receptor type 1A | 0.0095 | 0.1474 | 1 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0095 | 0.1474 | 0.5 |
Onchocerca volvulus | 0.0095 | 0.1474 | 0.5 | |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0095 | 0.1474 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0095 | 0.1474 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0095 | 0.1474 | 0.5 |
Onchocerca volvulus | 0.0095 | 0.1474 | 0.5 | |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0095 | 0.1474 | 0.5 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Brugia malayi | G-protein coupled receptor | 0.0095 | 0.1474 | 1 |
Schistosoma mansoni | amine GPCR | 0.0095 | 0.1474 | 0.5 |
Echinococcus multilocularis | serotonin receptor | 0.0095 | 0.1474 | 0.5 |
Schistosoma mansoni | myosin xvIII | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Echinococcus multilocularis | allatostatin A receptor | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0095 | 0.1474 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0095 | 0.1474 | 1 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0095 | 0.1474 | 0.5 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0095 | 0.1474 | 0.5 |
Onchocerca volvulus | 0.0095 | 0.1474 | 0.5 | |
Schistosoma mansoni | amine GPCR | 0.0095 | 0.1474 | 0.5 |
Schistosoma mansoni | neuropeptide receptor | 0.0095 | 0.1474 | 0.5 |
Schistosoma mansoni | amine GPCR | 0.0095 | 0.1474 | 0.5 |
Echinococcus granulosus | g protein coupled receptor | 0.0095 | 0.1474 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0095 | 0.1474 | 0.5 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0095 | 0.1474 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1474 | 1 |
Schistosoma mansoni | opsin-like receptor | 0.0095 | 0.1474 | 0.5 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0095 | 0.1474 | 0.5 |
Echinococcus multilocularis | serotonin receptor | 0.0095 | 0.1474 | 0.5 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0095 | 0.1474 | 0.5 |
Echinococcus multilocularis | neuropeptide receptor | 0.0095 | 0.1474 | 0.5 |
Onchocerca volvulus | 0.0095 | 0.1474 | 0.5 | |
Echinococcus granulosus | neuropeptides capa receptor | 0.0095 | 0.1474 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0095 | 0.1474 | 0.5 |
Mycobacterium ulcerans | penicillin-binding protein PbpA | 0.0251 | 0.6209 | 0.4101 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0095 | 0.1474 | 0.5 |
Brugia malayi | AKH receptor | 0.0095 | 0.1474 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0095 | 0.1474 | 0.5 |
Brugia malayi | GnHR receptor homolog | 0.0095 | 0.1474 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (ADMET) | = 0.54 % | Biliary excretion in bile duct cannulated rat assessed as radioactivity at 10 mg/kg, iv after 48 h | ChEMBL. | 17074792 |
Activity (ADMET) | = 7.5 % | Fecal excretion ratio in monkey assessed as radioactivity at 10 mg/kg, iv after 7 days | ChEMBL. | 17074792 |
Activity (ADMET) | = 12.5 % | Fecal excretion ratio in rat assessed as radioactivity at 10 mg/kg, iv after 7 days | ChEMBL. | 17074792 |
Activity (ADMET) | = 87.1 % | Urinary excretion ratio in rat assessed as radioactivity at 10 mg/kg, iv after 7 days | ChEMBL. | 17074792 |
Activity (ADMET) | = 88 % | Urinary excretion ratio in monkey assessed as radioactivity at 10 mg/kg, iv after 7 days | ChEMBL. | 17074792 |
AUC (ADMET) | = 26.8 ug.hr/ml | AUC (0-inf) in rat assessed as radioactivity at 10 mg/kg, iv | ChEMBL. | 17074792 |
AUC (ADMET) | = 87.4 ug.hr/ml | AUC (0-inf) in monkey assessed as radioactivity at 10 mg/kg, iv | ChEMBL. | 17074792 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.