Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | protein kinase, putative | 0.005 | 0 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0197 | 0.2688 | 0.5 |
Echinococcus granulosus | calpain A | 0.0198 | 0.2708 | 0.2409 |
Trypanosoma brucei | calpain-like protein, putative | 0.0071 | 0.0393 | 0.1462 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0197 | 0.2688 | 0.2389 |
Giardia lamblia | Cathepsin B precursor | 0.0197 | 0.2688 | 0.5 |
Entamoeba histolytica | calpain large subunit domain III containing protein | 0.005 | 0 | 0.5 |
Echinococcus granulosus | cathepsin b | 0.0596 | 1 | 1 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0189 | 0.2551 | 0.2246 |
Loa Loa (eye worm) | hypothetical protein | 0.0118 | 0.1244 | 0.1244 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0197 | 0.2688 | 1 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0071 | 0.0393 | 0.0393 |
Echinococcus multilocularis | cathepsin b | 0.0596 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0197 | 0.2688 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0071 | 0.0393 | 0.0393 |
Brugia malayi | calpain family protein 1 | 0.0189 | 0.2551 | 0.2551 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0596 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0197 | 0.2688 | 0.5 |
Loa Loa (eye worm) | calpain | 0.0071 | 0.0393 | 0.0393 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0596 | 1 | 1 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0071 | 0.0393 | 0.0393 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0197 | 0.2688 | 0.2688 |
Leishmania major | calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative | 0.0071 | 0.0393 | 0.1462 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0071 | 0.0393 | 0.0393 |
Echinococcus multilocularis | cathepsin b | 0.0596 | 1 | 1 |
Echinococcus multilocularis | calpain family protein 1, d | 0.0139 | 0.1637 | 0.1295 |
Loa Loa (eye worm) | cathepsin B | 0.0197 | 0.2688 | 0.2688 |
Brugia malayi | calpain 7 | 0.0071 | 0.0393 | 0.0393 |
Trypanosoma brucei | calpain-like cysteine peptidase, putative | 0.0071 | 0.0393 | 0.1462 |
Onchocerca volvulus | 0.0118 | 0.1244 | 0.5 | |
Trypanosoma cruzi | calpain cysteine peptidase, putative | 0.0071 | 0.0393 | 0.0393 |
Trypanosoma brucei | antigen, putative | 0.0071 | 0.0393 | 0.1462 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0198 | 0.2708 | 0.2409 |
Toxoplasma gondii | cathepsin B | 0.0197 | 0.2688 | 0.5 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0139 | 0.1637 | 0.1637 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.1637 | 0.1637 |
Trypanosoma brucei | calpain-like protein, putative | 0.0071 | 0.0393 | 0.1462 |
Trypanosoma brucei | calpain-like protein, putative | 0.0071 | 0.0393 | 0.1462 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0071 | 0.0393 | 0.0393 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0197 | 0.2688 | 1 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0071 | 0.0393 | 0.0393 |
Echinococcus granulosus | family C2 unassigned peptidase C02 family | 0.0198 | 0.2708 | 0.2409 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0071 | 0.0393 | 0.0393 |
Echinococcus multilocularis | calpain A | 0.0198 | 0.2708 | 0.2409 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C2, putative | 0.0071 | 0.0393 | 0.1462 |
Leishmania major | calpain, putative,cysteine peptidase, Clan CA, family C2, putative | 0.0071 | 0.0393 | 0.1462 |
Echinococcus granulosus | cathepsin b | 0.0596 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.2158 | 0.2158 |
Brugia malayi | calpain family protein 1 | 0.0189 | 0.2551 | 0.2551 |
Loa Loa (eye worm) | hypothetical protein | 0.0189 | 0.2551 | 0.2551 |
Leishmania major | calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative | 0.0071 | 0.0393 | 0.1462 |
Echinococcus multilocularis | family C2 unassigned peptidase (C02 family) | 0.0198 | 0.2708 | 0.2409 |
Trypanosoma brucei | calpain-like protein, putative | 0.0071 | 0.0393 | 0.1462 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0596 | 1 | 1 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0198 | 0.2708 | 0.2409 |
Loa Loa (eye worm) | hypothetical protein | 0.0596 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0596 | 1 | 1 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0071 | 0.0393 | 0.0393 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0596 | 1 | 1 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0189 | 0.2551 | 0.2551 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0071 | 0.0393 | 0.0393 |
Plasmodium vivax | calpain, putative | 0.0071 | 0.0393 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | 0 | Inhibition of DNA-PK in HeLa cell nuclear extracts | ChEMBL. | 17371003 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.