Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0305 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0075 | 0.1229 | 0.4887 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.3245 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.3245 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0075 | 0.1229 | 0.1229 |
Brugia malayi | Cathepsin L-like precursor | 0.0075 | 0.1229 | 0.1229 |
Echinococcus multilocularis | cathepsin b | 0.0305 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0075 | 0.1229 | 1 |
Plasmodium vivax | vivapain-2 | 0.0075 | 0.1229 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0075 | 0.1229 | 0.1229 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0075 | 0.1229 | 0.1229 |
Loa Loa (eye worm) | cathepsin B | 0.0109 | 0.2514 | 0.221 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0075 | 0.1229 | 0.4887 |
Brugia malayi | Cathepsin L-like precursor | 0.0075 | 0.1229 | 0.1229 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0128 | 0.3245 | 0.3245 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0075 | 0.1229 | 0.4887 |
Toxoplasma gondii | cathepsin B | 0.0109 | 0.2514 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0075 | 0.1229 | 0.1229 |
Echinococcus multilocularis | cathepsin b | 0.0305 | 1 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0053 | 0.0391 | 0.0391 |
Loa Loa (eye worm) | ctsf protein | 0.0075 | 0.1229 | 0.0872 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0109 | 0.2514 | 0.7748 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0075 | 0.1229 | 0.0872 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0305 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0075 | 0.1229 | 0.4887 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0075 | 0.1229 | 0.1229 |
Giardia lamblia | Cathepsin B precursor | 0.0109 | 0.2514 | 0.5 |
Onchocerca volvulus | 0.0075 | 0.1229 | 1 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0128 | 0.3245 | 0.3245 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0075 | 0.1229 | 0.4887 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0075 | 0.1229 | 0.4887 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0075 | 0.1229 | 0.4887 |
Leishmania major | cathepsin L-like protease | 0.0128 | 0.3245 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0075 | 0.1229 | 0.1229 |
Echinococcus multilocularis | cysteine protease | 0.0075 | 0.1229 | 0.1229 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0305 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.0305 | 1 | 1 |
Onchocerca volvulus | 0.0075 | 0.1229 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.3245 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0075 | 0.1229 | 0.1229 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0075 | 0.1229 | 0.1229 |
Brugia malayi | Cathepsin L-like precursor | 0.0075 | 0.1229 | 0.1229 |
Echinococcus multilocularis | cysteine protease | 0.0075 | 0.1229 | 0.1229 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0075 | 0.1229 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.3245 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0075 | 0.1229 | 0.4887 |
Onchocerca volvulus | 0.0075 | 0.1229 | 1 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0109 | 0.2514 | 0.2514 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.3245 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0075 | 0.1229 | 0.4887 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0128 | 0.3245 | 0.3245 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0075 | 0.1229 | 0.4887 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0106 | 0.2407 | 0.2407 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0128 | 0.3245 | 0.3245 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0075 | 0.1229 | 0.4887 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0109 | 0.2514 | 0.6376 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0053 | 0.0391 | 0.1555 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.3245 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.3245 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0075 | 0.1229 | 0.4887 |
Loa Loa (eye worm) | fibroinase | 0.0075 | 0.1229 | 0.0872 |
Onchocerca volvulus | 0.0075 | 0.1229 | 1 | |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0075 | 0.1229 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0053 | 0.0391 | 0.1555 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0075 | 0.1229 | 0.4887 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0075 | 0.1229 | 0.4887 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0074 | 0.1179 | 0.1179 |
Onchocerca volvulus | Cathepsin L homolog | 0.0075 | 0.1229 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0075 | 0.1229 | 0.4887 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0075 | 0.1229 | 0.4887 |
Entamoeba histolytica | cysteine protease, putative | 0.0075 | 0.1229 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0305 | 1 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0053 | 0.0391 | 0.0391 |
Leishmania major | cathepsin L-like protease | 0.0128 | 0.3245 | 1 |
Leishmania major | cathepsin L-like protease | 0.0128 | 0.3245 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.3245 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0053 | 0.0391 | 0.0391 |
Onchocerca volvulus | 0.0075 | 0.1229 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0075 | 0.1229 | 0.4887 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0075 | 0.1229 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0075 | 0.1229 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.3245 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0053 | 0.0391 | 0.3182 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0075 | 0.1229 | 0.1229 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0075 | 0.1229 | 0.4887 |
Giardia lamblia | Cathepsin B precursor | 0.0109 | 0.2514 | 0.5 |
Echinococcus granulosus | cathepsin l1 | 0.0075 | 0.1229 | 0.1229 |
Giardia lamblia | Cathepsin B precursor | 0.0109 | 0.2514 | 0.5 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0075 | 0.1229 | 0.1229 |
Echinococcus granulosus | cathepsin b | 0.0305 | 1 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0075 | 0.1229 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0305 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0053 | 0.0391 | 0.0391 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0075 | 0.1229 | 0.4887 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.3245 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0075 | 0.1229 | 0.4887 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0075 | 0.1229 | 0.0872 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0305 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0075 | 0.1229 | 0.4887 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0075 | 0.1229 | 0.1229 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0109 | 0.2514 | 0.2514 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0075 | 0.1229 | 0.4887 |
Echinococcus granulosus | cathepsin l1 | 0.0053 | 0.0391 | 0.0391 |
Brugia malayi | Cathepsin L-like precursor | 0.0075 | 0.1229 | 0.1229 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.3245 | 1 |
Onchocerca volvulus | 0.0075 | 0.1229 | 1 | |
Brugia malayi | Papain family cysteine protease containing protein | 0.0075 | 0.1229 | 0.1229 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0075 | 0.1229 | 0.4887 |
Plasmodium vivax | vivapain-2 | 0.0075 | 0.1229 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.1229 | 0.0872 |
Loa Loa (eye worm) | cysteine protease | 0.0075 | 0.1229 | 0.0872 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0075 | 0.1229 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0109 | 0.2514 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0075 | 0.1229 | 0.4887 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0075 | 0.1229 | 0.4887 |
Brugia malayi | Cathepsin L-like precursor | 0.0053 | 0.0391 | 0.0391 |
Onchocerca volvulus | 0.0075 | 0.1229 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.