Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0117 | 0.6594 | 0.6594 |
Onchocerca volvulus | 0.0019 | 0.0366 | 0.3348 | |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0019 | 0.0366 | 0.0449 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0049 | 0.2284 | 0.2605 |
Echinococcus granulosus | serine threonine protein kinase nrc | 0.0107 | 0.5926 | 0.7275 |
Plasmodium vivax | glutathione reductase, putative | 0.0142 | 0.8146 | 0.8715 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0049 | 0.2284 | 0.2803 |
Echinococcus granulosus | nervana 2 | 0.0106 | 0.5851 | 0.7183 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0049 | 0.2284 | 0.2803 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.0026 | 0.0797 | 0.0797 |
Trichomonas vaginalis | AGC family protein kinase | 0.0171 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0066 | 0.332 | 0.4075 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0366 | 0.0366 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.0055 | 0.2655 | 0.2655 |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.014 | 0.8018 | 0.8018 |
Entamoeba histolytica | protein kinase, putative | 0.0161 | 0.9332 | 0.9332 |
Trypanosoma cruzi | carnitine/choline acetyltransferase, putative | 0.0026 | 0.0797 | 0.0978 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0366 | 0.0366 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0366 | 0.0366 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.2655 | 0.2655 |
Trypanosoma cruzi | carnitine/choline acetyltransferase, putative | 0.0026 | 0.0797 | 0.0978 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0106 | 0.5851 | 0.7183 |
Onchocerca volvulus | 0.003 | 0.1094 | 1 | |
Schistosoma mansoni | serine/threonine protein kinase | 0.0055 | 0.2655 | 0.326 |
Echinococcus multilocularis | choline O acetyltransferase | 0.0026 | 0.0797 | 0.0978 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0049 | 0.2284 | 0.2284 |
Echinococcus granulosus | cathepsin l1 | 0.0019 | 0.0366 | 0.0449 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0049 | 0.2284 | 0.2284 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0072 | 0.3714 | 0.4559 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0049 | 0.2284 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0171 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0026 | 0.0797 | 0.0978 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.0161 | 0.9332 | 0.9332 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0142 | 0.8146 | 0.8715 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.0055 | 0.2655 | 0.2655 |
Schistosoma mansoni | choline o-acyltransferase | 0.0026 | 0.0797 | 0.0978 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0055 | 0.2655 | 0.326 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0049 | 0.2284 | 0.2284 |
Onchocerca volvulus | 0.0019 | 0.0366 | 0.3348 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0019 | 0.0366 | 0.0366 |
Plasmodium falciparum | glutathione reductase | 0.0049 | 0.2284 | 0.2443 |
Echinococcus multilocularis | serine threonine protein kinase | 0.0055 | 0.2655 | 0.326 |
Mycobacterium ulcerans | methyltransferase | 0.0152 | 0.8767 | 1 |
Leishmania major | cathepsin L-like protease | 0.0072 | 0.3714 | 0.4559 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0066 | 0.0066 |
Brugia malayi | Thioredoxin reductase | 0.0142 | 0.8146 | 0.8146 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0049 | 0.2284 | 0.2605 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0036 | 0.1458 | 0.1458 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0072 | 0.3714 | 0.3714 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0019 | 0.0366 | 0.0449 |
Onchocerca volvulus | 0.0019 | 0.0366 | 0.3348 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0072 | 0.3714 | 0.3714 |
Loa Loa (eye worm) | fibroinase | 0.0019 | 0.0366 | 0.0366 |
Schistosoma mansoni | choline o-acyltransferase | 0.0026 | 0.0797 | 0.0978 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0117 | 0.6594 | 0.8095 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0049 | 0.2284 | 0.2605 |
Plasmodium falciparum | RAC-beta serine/threonine protein kinase | 0.0107 | 0.5926 | 0.634 |
Trypanosoma brucei | carnitine O-palmitoyltransferase, putative | 0.0026 | 0.0797 | 0.0797 |
Plasmodium falciparum | glutathione reductase | 0.0142 | 0.8146 | 0.8715 |
Leishmania major | carnitine/choline acetyltransferase, putative | 0.0026 | 0.0797 | 0.0978 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0049 | 0.2284 | 0.2284 |
Echinococcus multilocularis | Ribosomal protein S6 kinase beta 2 | 0.0055 | 0.2655 | 0.326 |
Entamoeba histolytica | protein kinase, putative | 0.0171 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0366 | 0.0366 |
Echinococcus granulosus | lamin dm0 | 0.003 | 0.1094 | 0.1342 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0049 | 0.2284 | 0.2284 |
Trypanosoma cruzi | carnitine O-acetyltransferase, putative | 0.0026 | 0.0797 | 0.0978 |
Trichomonas vaginalis | AGC family protein kinase | 0.0055 | 0.2655 | 0.2655 |
Treponema pallidum | NADH oxidase | 0.0049 | 0.2284 | 1 |
Schistosoma mansoni | atypical protein kinase C | 0.0055 | 0.2655 | 0.326 |
Leishmania major | cathepsin L-like protease | 0.0019 | 0.0366 | 0.0449 |
Echinococcus granulosus | protein kinase c iota type | 0.0055 | 0.2655 | 0.326 |
Plasmodium vivax | vivapain-2 | 0.0019 | 0.0366 | 0.0392 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0101 | 0.0101 |
Echinococcus multilocularis | cysteine protease | 0.0019 | 0.0366 | 0.0449 |
Echinococcus multilocularis | ribosomal protein S6 kinase alpha 3 | 0.0055 | 0.2655 | 0.326 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0049 | 0.2284 | 0.2284 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0049 | 0.2284 | 0.2803 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0019 | 0.0366 | 0.0449 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0055 | 0.2655 | 0.326 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0019 | 0.0366 | 0.0366 |
Brugia malayi | Protein kinase domain containing protein | 0.0055 | 0.2655 | 0.2655 |
Echinococcus granulosus | protein kinase C gamma type | 0.0055 | 0.2655 | 0.326 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0366 | 0.0366 |
Toxoplasma gondii | AGC kinase | 0.0161 | 0.9332 | 1 |
Echinococcus granulosus | Ribosomal protein S6 kinase beta 2 | 0.0055 | 0.2655 | 0.326 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0049 | 0.2284 | 0.2284 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0036 | 0.1458 | 0.1458 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0049 | 0.2284 | 0.2803 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0366 | 0.0366 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0072 | 0.3714 | 0.3714 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0072 | 0.3714 | 0.3714 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.003 | 0.1094 | 0.1094 |
Loa Loa (eye worm) | choline O-acetyltransferase | 0.0026 | 0.0797 | 0.0797 |
Echinococcus multilocularis | lamin dm0 | 0.003 | 0.1094 | 0.1342 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0366 | 0.0366 |
Trypanosoma cruzi | choline/carnitine O-acetyltransferase, putative | 0.0026 | 0.0797 | 0.0978 |
Loa Loa (eye worm) | choline/Carnitine O-acyltransferase | 0.0026 | 0.0797 | 0.0797 |
Onchocerca volvulus | 0.0026 | 0.0797 | 0.7285 | |
Brugia malayi | Choline/Carnitine o-acyltransferase family protein | 0.0026 | 0.0797 | 0.0797 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0019 | 0.0366 | 0.0392 |
Toxoplasma gondii | thioredoxin reductase | 0.0142 | 0.8146 | 0.873 |
Schistosoma mansoni | lamin | 0.003 | 0.1094 | 0.1342 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0026 | 0.0797 | 0.0978 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0019 | 0.0366 | 0.0366 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0366 | 0.0366 |
Onchocerca volvulus | 0.0026 | 0.0797 | 0.7285 | |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0019 | 0.0366 | 0.0449 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0055 | 0.2655 | 0.326 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0049 | 0.2284 | 0.2443 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0016 | 0.0203 | 0.0203 |
Echinococcus multilocularis | carnitine O palmitoyltransferase 2 | 0.0026 | 0.0797 | 0.0978 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0171 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0072 | 0.3714 | 0.4559 |
Echinococcus granulosus | ribosomal protein S6 kinase alpha 3 | 0.0055 | 0.2655 | 0.326 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0366 | 0.0366 |
Leishmania major | cathepsin L-like protease | 0.0019 | 0.0366 | 0.0449 |
Trichomonas vaginalis | AGC family protein kinase | 0.0066 | 0.3324 | 0.3324 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0049 | 0.2284 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0019 | 0.0366 | 0.0449 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0366 | 0.0366 |
Loa Loa (eye worm) | cysteine protease | 0.0019 | 0.0366 | 0.0366 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0019 | 0.0366 | 0.0449 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0366 | 0.0366 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0019 | 0.0366 | 0.0366 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0107 | 0.5926 | 0.7275 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0049 | 0.2284 | 0.2803 |
Onchocerca volvulus | 0.0019 | 0.0366 | 0.3348 | |
Entamoeba histolytica | protein kinase, putative | 0.0171 | 1 | 1 |
Echinococcus multilocularis | serine threonine protein kinase nrc serine threonine protein kinase gad | 0.0107 | 0.5926 | 0.7275 |
Giardia lamblia | Kinase, AGC PKA | 0.0107 | 0.5926 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0366 | 0.0366 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0142 | 0.8146 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0019 | 0.0366 | 0.0449 |
Trypanosoma brucei | carnitine O-palmitoyltransferase II, putative | 0.0026 | 0.0797 | 0.0797 |
Trichomonas vaginalis | AGC family protein kinase | 0.0171 | 1 | 1 |
Brugia malayi | Choline O-acetyltransferase | 0.0026 | 0.0797 | 0.0797 |
Trichomonas vaginalis | AGC family protein kinase | 0.0171 | 1 | 1 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.0026 | 0.0797 | 0.0978 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0366 | 0.0366 |
Leishmania major | cysteine peptidase A (CPA) | 0.0019 | 0.0366 | 0.0449 |
Plasmodium falciparum | thioredoxin reductase | 0.0142 | 0.8146 | 0.8715 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0019 | 0.0366 | 0.0366 |
Onchocerca volvulus | Cathepsin L homolog | 0.0019 | 0.0366 | 0.3348 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0142 | 0.8146 | 0.9292 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0366 | 0.0366 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0019 | 0.0366 | 0.0366 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0049 | 0.2284 | 0.2605 |
Echinococcus granulosus | Glutaredoxin protein 5 | 0.0106 | 0.5851 | 0.7183 |
Trypanosoma brucei | trypanothione reductase | 0.0142 | 0.8146 | 0.8146 |
Entamoeba histolytica | protein kinase, putative | 0.0055 | 0.2655 | 0.2655 |
Trichomonas vaginalis | AGC family protein kinase | 0.0171 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0055 | 0.2655 | 0.326 |
Trypanosoma cruzi | Protein kinase B | 0.0117 | 0.6594 | 0.8095 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0366 | 0.0366 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0366 | 0.0366 |
Mycobacterium tuberculosis | Possible mycolic acid synthase UmaA | 0.0152 | 0.8767 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0055 | 0.2655 | 0.326 |
Onchocerca volvulus | Cathepsin L homolog | 0.0019 | 0.0366 | 0.3348 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0366 | 0.0366 |
Leishmania major | choline/Carnitine o-acyltransferase-like protein | 0.014 | 0.8018 | 0.9842 |
Echinococcus granulosus | carnitine O palmitoyltransferase 1 liver | 0.014 | 0.8018 | 0.9842 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0142 | 0.8146 | 1 |
Echinococcus multilocularis | protein kinase c iota type | 0.0055 | 0.2655 | 0.326 |
Echinococcus multilocularis | lamin | 0.003 | 0.1094 | 0.1342 |
Loa Loa (eye worm) | glutathione reductase | 0.0142 | 0.8146 | 0.8146 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0026 | 0.0797 | 0.0978 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.003 | 0.1094 | 0.1094 |
Echinococcus granulosus | choline O acetyltransferase | 0.0026 | 0.0797 | 0.0978 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0171 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0019 | 0.0366 | 0.0449 |
Plasmodium vivax | vivapain-2 | 0.0019 | 0.0366 | 0.0392 |
Echinococcus multilocularis | Glutaredoxin protein 5 | 0.0106 | 0.5851 | 0.7183 |
Echinococcus granulosus | serine/threonine protein kinase | 0.0117 | 0.6594 | 0.8095 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0049 | 0.2284 | 0.2447 |
Trypanosoma brucei | carnitine O-acetyltransferase, putative | 0.0026 | 0.0797 | 0.0797 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0366 | 0.0366 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0015 | 0.0101 | 0.0124 |
Schistosoma mansoni | intermediate filament proteins | 0.003 | 0.1094 | 0.1342 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0049 | 0.2284 | 0.2605 |
Onchocerca volvulus | 0.0019 | 0.0366 | 0.3348 | |
Trichomonas vaginalis | AGC family protein kinase | 0.0171 | 1 | 1 |
Onchocerca volvulus | 0.0019 | 0.0366 | 0.3348 | |
Loa Loa (eye worm) | ctsf protein | 0.0019 | 0.0366 | 0.0366 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0366 | 0.0366 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0366 | 0.0366 |
Echinococcus multilocularis | cysteine protease | 0.0019 | 0.0366 | 0.0449 |
Trichomonas vaginalis | serine/threonine-protein kinase sgk, putative | 0.0054 | 0.258 | 0.258 |
Echinococcus granulosus | ribosomal protein s6 kinase beta 1 | 0.0055 | 0.2655 | 0.326 |
Brugia malayi | Choline O-acetyltransferase | 0.0026 | 0.0797 | 0.0797 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0072 | 0.3714 | 0.3714 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0366 | 0.0366 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0072 | 0.3714 | 0.3714 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0366 | 0.0366 |
Leishmania major | cathepsin L-like protease | 0.0019 | 0.0366 | 0.0449 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0019 | 0.0366 | 0.0366 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0019 | 0.0366 | 0.0449 |
Schistosoma mansoni | serine/threonine kinase | 0.0055 | 0.2655 | 0.326 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0026 | 0.0797 | 0.0797 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0072 | 0.3714 | 0.3714 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0049 | 0.2284 | 0.2803 |
Echinococcus multilocularis | serine:threonine protein kinase 38 | 0.0055 | 0.2655 | 0.326 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0019 | 0.0366 | 0.0449 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0049 | 0.2284 | 0.2803 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0366 | 0.0366 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0117 | 0.6594 | 0.6594 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0055 | 0.2655 | 0.2655 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0072 | 0.3714 | 0.4559 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0055 | 0.2655 | 0.326 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0016 | 0.0203 | 0.0203 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0072 | 0.3714 | 0.3714 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0049 | 0.2284 | 0.2803 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.0055 | 0.2655 | 0.2655 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0049 | 0.2284 | 0.3854 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0366 | 0.0366 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.0055 | 0.2655 | 0.2655 |
Echinococcus multilocularis | nervana 2 | 0.0106 | 0.5851 | 0.7183 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0049 | 0.2284 | 0.2447 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0142 | 0.8146 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0055 | 0.2655 | 0.326 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0055 | 0.2655 | 0.326 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0117 | 0.6594 | 0.8095 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0055 | 0.2655 | 0.326 |
Echinococcus multilocularis | musashi | 0.003 | 0.1094 | 0.1342 |
Toxoplasma gondii | cathepsin CPL | 0.0019 | 0.0366 | 0.0392 |
Echinococcus multilocularis | nervana 2 | 0.0106 | 0.5851 | 0.7183 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0019 | 0.0366 | 0.0392 |
Entamoeba histolytica | cysteine protease, putative | 0.0019 | 0.0366 | 0.0366 |
Trichomonas vaginalis | AGC family protein kinase | 0.0055 | 0.2655 | 0.2655 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0015 | 0.0101 | 0.0124 |
Onchocerca volvulus | Cathepsin F homolog | 0.0019 | 0.0366 | 0.3348 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0049 | 0.2284 | 0.2803 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0072 | 0.3714 | 0.3714 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0072 | 0.3714 | 0.4559 |
Brugia malayi | Protein kinase domain containing protein | 0.0055 | 0.2655 | 0.2655 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0072 | 0.3714 | 0.4559 |
Echinococcus granulosus | lamin | 0.003 | 0.1094 | 0.1342 |
Echinococcus multilocularis | ribosomal protein s6 kinase beta 1 | 0.0055 | 0.2655 | 0.326 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0049 | 0.2284 | 0.2803 |
Mycobacterium ulcerans | mycolic acid synthase UmaA | 0.0152 | 0.8767 | 1 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0049 | 0.2284 | 0.2443 |
Onchocerca volvulus | 0.0026 | 0.0797 | 0.7285 | |
Plasmodium falciparum | phosphoethanolamine N-methyltransferase | 0.0161 | 0.9347 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0055 | 0.2655 | 0.326 |
Echinococcus multilocularis | carnitine O palmitoyltransferase 1, liver | 0.014 | 0.8018 | 0.9842 |
Trichomonas vaginalis | AGC family protein kinase | 0.0055 | 0.2655 | 0.2655 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0049 | 0.2284 | 0.2605 |
Trypanosoma brucei | carnitine O-palmitoyltransferase II, putative | 0.0026 | 0.0797 | 0.0797 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0066 | 0.0066 |
Leishmania major | trypanothione reductase | 0.0142 | 0.8146 | 1 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0056 | 0.2742 | 0.3366 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0026 | 0.0797 | 0.0978 |
Echinococcus granulosus | nervana 2 | 0.0106 | 0.5851 | 0.7183 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0049 | 0.2284 | 0.2443 |
Leishmania major | carnitine palmitoyltransferase-like protein | 0.0026 | 0.0797 | 0.0978 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0049 | 0.2284 | 0.2803 |
Onchocerca volvulus | 0.0026 | 0.0797 | 0.7285 | |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0161 | 0.9332 | 0.9332 |
Loa Loa (eye worm) | carnitine O-palmitoyltransferase I isoform | 0.0026 | 0.0797 | 0.0797 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0026 | 0.0797 | 0.0978 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0072 | 0.3714 | 0.3714 |
Echinococcus granulosus | intermediate filament protein | 0.003 | 0.1094 | 0.1342 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0019 | 0.0366 | 0.0366 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0049 | 0.2284 | 0.2443 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0106 | 0.5851 | 0.7183 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.8018 | 0.8018 |
Echinococcus granulosus | NDR protein kinase | 0.0055 | 0.2655 | 0.326 |
Brugia malayi | glutathione reductase | 0.0142 | 0.8146 | 0.8146 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0055 | 0.2655 | 0.326 |
Brugia malayi | Hr1 repeat family protein | 0.0055 | 0.2655 | 0.2655 |
Trypanosoma cruzi | carnitine O-palmitoyltransferase II, putative | 0.0026 | 0.0797 | 0.0978 |
Echinococcus multilocularis | rac serine:threonine kinase | 0.0117 | 0.6594 | 0.8095 |
Brugia malayi | intermediate filament protein | 0.003 | 0.1094 | 0.1094 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0019 | 0.0366 | 0.0392 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0049 | 0.2284 | 0.2803 |
Trichomonas vaginalis | AGC family protein kinase | 0.0171 | 1 | 1 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0142 | 0.8146 | 0.8146 |
Entamoeba histolytica | protein kinase 2, putative | 0.0107 | 0.5926 | 0.5926 |
Loa Loa (eye worm) | intermediate filament protein | 0.003 | 0.1094 | 0.1094 |
Plasmodium falciparum | thioredoxin reductase | 0.0049 | 0.2284 | 0.2443 |
Brugia malayi | protein kinase C II. | 0.0055 | 0.2655 | 0.2655 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0049 | 0.2284 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.1058 | 0.1058 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0049 | 0.2284 | 0.2803 |
Plasmodium vivax | rac-beta serine/threonine protein kinase, putative | 0.0107 | 0.5926 | 0.634 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0797 | 0.0797 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0055 | 0.2655 | 0.2655 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0072 | 0.3714 | 0.3714 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0055 | 0.2655 | 0.326 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0366 | 0.0366 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0117 | 0.6594 | 0.8095 |
Leishmania major | cathepsin L-like protease | 0.0019 | 0.0366 | 0.0449 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0366 | 0.0366 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0049 | 0.2284 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0366 | 0.0366 |
Leishmania major | cathepsin L-like protease | 0.0072 | 0.3714 | 0.4559 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0055 | 0.2655 | 0.326 |
Onchocerca volvulus | 0.003 | 0.1094 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.1094 | 0.1094 |
Echinococcus granulosus | carnitine O palmitoyltransferase 2 | 0.0026 | 0.0797 | 0.0978 |
Plasmodium vivax | phosphoethanolamine N-methyltransferase | 0.0161 | 0.9347 | 1 |
Mycobacterium tuberculosis | Possible methyltransferase (methylase) | 0.0152 | 0.8767 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0366 | 0.0366 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0049 | 0.2284 | 0.2803 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0049 | 0.2284 | 0.2605 |
Schistosoma mansoni | lamin | 0.003 | 0.1094 | 0.1342 |
Onchocerca volvulus | 0.0019 | 0.0366 | 0.3348 | |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.014 | 0.8018 | 0.9842 |
Brugia malayi | Cathepsin L-like precursor | 0.0019 | 0.0366 | 0.0366 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase | 0.0107 | 0.5926 | 0.7275 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0049 | 0.2284 | 0.2803 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0049 | 0.2284 | 0.2803 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.014 | 0.8018 | 0.9842 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (ADMET) | 0 | Cytotoxicity against human KB cells after 72 hrs | ChEMBL. | 17064914 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.