Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | glycogen phosphorylase | 0.4209 | 1 | 1 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.4209 | 1 | 1 |
Schistosoma mansoni | glycogen phosphorylase | 0.4209 | 1 | 1 |
Echinococcus granulosus | glycogen phosphorylase | 0.4209 | 1 | 1 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.182 | 0.4315 | 0.4315 |
Chlamydia trachomatis | glycogen phosphorylase | 0.4209 | 1 | 0.5 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.4209 | 1 | 0.5 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.4209 | 1 | 1 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.182 | 0.4315 | 0.5 |
Echinococcus multilocularis | tyrosine protein kinase shark | 0.0214 | 0.0495 | 0.0495 |
Schistosoma mansoni | glycogen phosphorylase | 0.4209 | 1 | 1 |
Schistosoma mansoni | glycogen phosphorylase | 0.182 | 0.4315 | 0.4315 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.4209 | 1 | 1 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.4209 | 1 | 1 |
Echinococcus granulosus | glycogen phosphorylase | 0.4209 | 1 | 1 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.4209 | 1 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0214 | 0.0495 | 0.0495 |
Giardia lamblia | Glycogen phosphorylase | 0.4209 | 1 | 0.5 |
Mycobacterium ulcerans | glycogen phosphorylase GlgP | 0.182 | 0.4315 | 0.5 |
Entamoeba histolytica | glycogenphosphorylase, putative | 0.182 | 0.4315 | 0.4315 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.4209 | 1 | 1 |
Echinococcus multilocularis | glycogen phosphorylase | 0.4209 | 1 | 1 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.4209 | 1 | 1 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.182 | 0.4315 | 0.4315 |
Echinococcus granulosus | tyrosine protein kinase shark | 0.0214 | 0.0495 | 0.0495 |
Schistosoma mansoni | tyrosine kinase | 0.0209 | 0.0483 | 0.0483 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Diet (functional) | = 57 % | In vivo triglyceride lowering activity dosed at 0.10 % of the diet. | ChEMBL. | 6604817 |
Diet (functional) | = 94 % | In vivo sterol lowering activity at dose of 0.10 % of the diet | ChEMBL. | 6604817 |
Inhibition (binding) | < 34 % | In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase | ChEMBL. | 6604817 |
Inhibition (binding) | < 34 % | In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase | ChEMBL. | 6604817 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.