Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | transient receptor potential cation channel, subfamily V, member 1 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | plasmepsin IV | 0.0072 | 0.0559 | 1 |
Echinococcus multilocularis | lysosomal alpha mannosidase | 0.0079 | 0.0653 | 0.1902 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0533 | 0.6439 | 0.6367 |
Schistosoma mansoni | mannosidase alpha class 2a | 0.0044 | 0.02 | 0.0775 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0453 | 0.0453 |
Echinococcus granulosus | ceramide glucosyltransferase | 0.023 | 0.258 | 1 |
Schistosoma mansoni | lysosomal alpha-mannosidase (mannosidase alpha class 2b member 1) | 0.0079 | 0.0653 | 0.253 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0813 | 1 | 1 |
Echinococcus granulosus | bile acid beta glucosidase | 0.0201 | 0.2206 | 0.815 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0072 | 0.0559 | 0.2165 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0813 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.1389 | 0.1389 |
Trichomonas vaginalis | Clan AA, family A1, cathepsin D-like aspartic peptidase | 0.0072 | 0.0559 | 0.0366 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0813 | 1 | 1 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.023 | 0.258 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0813 | 1 | 1 |
Plasmodium vivax | aspartyl proteinase, putative | 0.0072 | 0.0559 | 1 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.0201 | 0.2206 | 0.8551 |
Echinococcus multilocularis | non lysosomal glucosylceramidase | 0.0201 | 0.2206 | 0.8429 |
Echinococcus granulosus | lysosomal alpha mannosidase | 0.0079 | 0.0653 | 0.0465 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0813 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0533 | 0.6439 | 0.6367 |
Toxoplasma gondii | aspartyl proteinase (eimepsin), putative | 0.0072 | 0.0559 | 0.5 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0533 | 0.6439 | 1 |
Loa Loa (eye worm) | ceramide glucosyltransferase | 0.023 | 0.258 | 0.258 |
Plasmodium falciparum | plasmepsin I | 0.0072 | 0.0559 | 1 |
Plasmodium vivax | plasmepsin IV, putative | 0.0072 | 0.0559 | 1 |
Trypanosoma cruzi | lysosomal alpha-mannosidase precursor, putative | 0.0079 | 0.0653 | 0.5 |
Schistosoma mansoni | beta-galactosidase | 0.0137 | 0.1389 | 0.5381 |
Giardia lamblia | Ceramide glucosyltransferase | 0.0104 | 0.0976 | 0.5 |
Echinococcus granulosus | non lysosomal glucosylceramidase | 0.0201 | 0.2206 | 0.815 |
Plasmodium falciparum | plasmepsin VI | 0.0072 | 0.0559 | 1 |
Toxoplasma gondii | aspartyl protease ASP1 | 0.0072 | 0.0559 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0533 | 0.6439 | 0.6367 |
Loa Loa (eye worm) | glycosyl hydrolase family 38 protein | 0.0044 | 0.02 | 0.02 |
Schistosoma mansoni | lysosomal alpha-mannosidase (mannosidase alpha class 2b member 1) | 0.0044 | 0.02 | 0.0775 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0072 | 0.0559 | 0.2165 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0533 | 0.6439 | 0.6367 |
Echinococcus multilocularis | beta galactosidase | 0.0137 | 0.1389 | 0.4993 |
Trypanosoma brucei | lysosomal alpha-mannosidase precursor, putative | 0.0079 | 0.0653 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.02 | 0.02 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.023 | 0.258 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0562 | 0.6805 | 0.674 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0533 | 0.6439 | 0.6367 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.0201 | 0.2206 | 0.8551 |
Loa Loa (eye worm) | hypothetical protein | 0.0137 | 0.1389 | 0.1389 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0559 | 0.0559 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0813 | 1 | 1 |
Loa Loa (eye worm) | aspartic protease BmAsp-2 | 0.0072 | 0.0559 | 0.0559 |
Loa Loa (eye worm) | hypothetical protein | 0.0136 | 0.1374 | 0.1374 |
Echinococcus multilocularis | cathepsin d (lysosomal aspartyl protease) | 0.0072 | 0.0559 | 0.1507 |
Trypanosoma cruzi | lysosomal alpha-mannosidase precursor, putative | 0.0079 | 0.0653 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0813 | 1 | 1 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0072 | 0.0559 | 0.2165 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0562 | 0.6805 | 0.674 |
Onchocerca volvulus | Ceramide glucosyltransferase homolog | 0.023 | 0.258 | 0.3815 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0533 | 0.6439 | 0.6367 |
Echinococcus granulosus | beta galactosidase | 0.0137 | 0.1389 | 0.4105 |
Plasmodium falciparum | plasmepsin II | 0.0072 | 0.0559 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0533 | 0.6439 | 0.6367 |
Brugia malayi | Ceramide glucosyltransferase | 0.023 | 0.258 | 0.2429 |
Echinococcus multilocularis | bile acid beta glucosidase | 0.0201 | 0.2206 | 0.8429 |
Echinococcus multilocularis | ceramide glucosyltransferase | 0.023 | 0.258 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.02 | 0.02 |
Mycobacterium ulcerans | alpha-mannosidase | 0.0044 | 0.02 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.