Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Chlamydia trachomatis | protoporphyrinogen oxidase | 0.0282 | 0.5 | 0.5 |
Brugia malayi | hypothetical protein | 0.0282 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0282 | 0.5 | 0.5 |
Plasmodium vivax | lysine-specific histone demethylase 1, putative | 0.0282 | 0.5 | 0.5 |
Schistosoma mansoni | amine oxidase | 0.0282 | 0.5 | 0.5 |
Echinococcus multilocularis | lysine specific histone demethylase 1A | 0.0282 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 0.5 | 0.5 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0282 | 0.5 | 0.5 |
Schistosoma mansoni | Protoporphyrinogen oxidase chloroplast/mitochondrial precursor | 0.0282 | 0.5 | 0.5 |
Schistosoma mansoni | Lysine-specific histone demethylase 1 | 0.0282 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 0.5 | 0.5 |
Brugia malayi | amine oxidase, flavin-containing family protein | 0.0282 | 0.5 | 0.5 |
Mycobacterium ulcerans | monoamine oxidase | 0.0282 | 0.5 | 0.5 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0282 | 0.5 | 0.5 |
Mycobacterium leprae | PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) | 0.0282 | 0.5 | 0.5 |
Toxoplasma gondii | histone lysine-specific demethylase | 0.0282 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 0.5 | 0.5 |
Plasmodium falciparum | lysine-specific histone demethylase 1, putative | 0.0282 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 0.5 | 0.5 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0282 | 0.5 | 0.5 |
Echinococcus multilocularis | protoporphyrinogen oxidase | 0.0282 | 0.5 | 0.5 |
Plasmodium vivax | protoporphyrinogen oxidase, putative | 0.0282 | 0.5 | 0.5 |
Mycobacterium ulcerans | oxidoreductase | 0.0282 | 0.5 | 0.5 |
Plasmodium vivax | hypothetical protein, conserved | 0.0282 | 0.5 | 0.5 |
Mycobacterium ulcerans | dehydrogenase | 0.0282 | 0.5 | 0.5 |
Leishmania major | UDP-galactopyranose mutase | 0.0282 | 0.5 | 0.5 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0282 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0282 | 0.5 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 0.5 | 0.5 |
Mycobacterium ulcerans | protoporphyrinogen oxidase | 0.0282 | 0.5 | 0.5 |
Echinococcus multilocularis | 0.0282 | 0.5 | 0.5 | |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0282 | 0.5 | 0.5 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.0282 | 0.5 | 0.5 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.0282 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0282 | 0.5 | 0.5 |
Schistosoma mansoni | amine oxidase | 0.0282 | 0.5 | 0.5 |
Plasmodium vivax | hypothetical protein, conserved | 0.0282 | 0.5 | 0.5 |
Toxoplasma gondii | histone lysine-specific demethylase LSD1/BHC110/KDMA1A | 0.0282 | 0.5 | 0.5 |
Plasmodium falciparum | protoporphyrinogen oxidase | 0.0282 | 0.5 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.