Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | neuropeptide receptor | 0.0251 | 0.0989 | 0.2978 |
Schistosoma mansoni | amine GPCR | 0.0251 | 0.0989 | 0.2978 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0251 | 0.0989 | 0.2978 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0251 | 0.0989 | 0.2978 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0251 | 0.0989 | 0.2978 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0251 | 0.0989 | 0.2978 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Mycobacterium ulcerans | isocitrate lyase Icl | 0.1898 | 1 | 0.5 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative | 0.0104 | 0.0184 | 0.0406 |
Trypanosoma brucei | cAMP-specific phosphodiesterase | 0.0138 | 0.0369 | 1 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0251 | 0.0989 | 0.3511 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.017 | 0.0543 | 0.1518 |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0251 | 0.0989 | 0.3511 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0251 | 0.0989 | 0.2978 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Schistosoma mansoni | hypothetical protein | 0.0251 | 0.0989 | 0.2978 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0251 | 0.0989 | 0.2978 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0251 | 0.0989 | 0.3511 |
Brugia malayi | hypothetical protein | 0.0251 | 0.0989 | 0.3511 |
Brugia malayi | ORL1-like opioid receptor | 0.0251 | 0.0989 | 0.3511 |
Loa Loa (eye worm) | cyclic AMP specific phosphodiesterase PDE4D5A | 0.0559 | 0.2673 | 0.8519 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0072 | 0.0007 | 0.5 |
Schistosoma mansoni | cgmp-dependent 35-cyclic phosphodiesterase | 0.0104 | 0.0184 | 0.0344 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0251 | 0.0989 | 0.2978 |
Echinococcus multilocularis | neuropeptide receptor | 0.0251 | 0.0989 | 0.2978 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Brugia malayi | GnHR receptor homolog | 0.0251 | 0.0989 | 0.3511 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0251 | 0.0989 | 0.3153 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0251 | 0.0989 | 0.3153 |
Echinococcus multilocularis | cAMP and cAMP inhibited cGMP 3',5' cyclic | 0.0104 | 0.0184 | 0.0344 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0085 | 0.0079 | 0.1969 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0251 | 0.0989 | 0.3511 |
Onchocerca volvulus | 0.0251 | 0.0989 | 1 | |
Loa Loa (eye worm) | TYRA-2 protein | 0.0251 | 0.0989 | 0.3153 |
Brugia malayi | AKH receptor | 0.0251 | 0.0989 | 0.3511 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Brugia malayi | G protein-coupled receptor | 0.0251 | 0.0989 | 0.3511 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0085 | 0.0079 | 0.1969 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0251 | 0.0989 | 0.2978 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0251 | 0.0989 | 0.2978 |
Treponema pallidum | fructose-bisphosphate aldolase | 0.0072 | 0.0007 | 0.5 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0559 | 0.2673 | 0.8481 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Echinococcus granulosus | neuropeptide receptor | 0.0251 | 0.0989 | 0.2978 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0251 | 0.0989 | 0.3511 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Schistosoma mansoni | amine GPCR | 0.0251 | 0.0989 | 0.2978 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0251 | 0.0989 | 0.2978 |
Echinococcus granulosus | g-protein coupled receptor | 0.0251 | 0.0989 | 0.2978 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0251 | 0.0989 | 0.2978 |
Onchocerca volvulus | 0.0251 | 0.0989 | 1 | |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0251 | 0.0989 | 0.2978 |
Echinococcus granulosus | cAMP and cAMP inhibited cGMP 3'5' cyclic | 0.0104 | 0.0184 | 0.0344 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0251 | 0.0989 | 1 |
Plasmodium falciparum | cGMP-specific phosphodiesterase | 0.0085 | 0.0079 | 0.5 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0251 | 0.0989 | 0.2978 |
Brugia malayi | hypothetical protein | 0.0251 | 0.0989 | 0.3511 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0251 | 0.0989 | 0.2978 |
Onchocerca volvulus | 0.0251 | 0.0989 | 1 | |
Brugia malayi | Serotonin receptor | 0.0251 | 0.0989 | 0.3511 |
Trichomonas vaginalis | cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative | 0.0085 | 0.0079 | 0.1969 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0251 | 0.0989 | 0.2978 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0644 | 0.3137 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0251 | 0.0989 | 0.2978 |
Mycobacterium tuberculosis | Probable isocitrate lyase AceAb [second part] (isocitrase) (isocitratase) (Icl) | 0.1898 | 1 | 0.5 |
Echinococcus multilocularis | g protein coupled receptor | 0.0251 | 0.0989 | 0.2978 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0251 | 0.0989 | 0.2978 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.0184 | 0.0586 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0085 | 0.0079 | 0.1969 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0251 | 0.0989 | 0.2978 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0251 | 0.0989 | 0.2978 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0251 | 0.0989 | 0.2978 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0085 | 0.0079 | 0.1969 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0251 | 0.0989 | 0.2978 |
Schistosoma mansoni | biogenic amine receptor | 0.0251 | 0.0989 | 0.2978 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0251 | 0.0989 | 0.3153 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0251 | 0.0989 | 0.2978 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0251 | 0.0989 | 0.2978 |
Echinococcus multilocularis | fmrfamide receptor | 0.0251 | 0.0989 | 0.2978 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0251 | 0.0989 | 0.2978 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0251 | 0.0989 | 0.2978 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.0079 | 0.025 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0251 | 0.0989 | 0.2978 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0251 | 0.0989 | 0.2978 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Brugia malayi | G-protein coupled receptor | 0.0251 | 0.0989 | 0.3511 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0251 | 0.0989 | 0.2978 |
Schistosoma mansoni | subfamily M14A unassigned peptidase (M14 family) | 0.0085 | 0.008 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Mycobacterium tuberculosis | Isocitrate lyase Icl (isocitrase) (isocitratase) | 0.1898 | 1 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0251 | 0.0989 | 0.2978 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0251 | 0.0989 | 0.2978 |
Brugia malayi | hypothetical protein | 0.0251 | 0.0989 | 0.3511 |
Brugia malayi | neuropeptide F receptor | 0.0251 | 0.0989 | 0.3511 |
Giardia lamblia | hypothetical protein | 0.0085 | 0.0079 | 0.0227 |
Trichomonas vaginalis | cone cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0251 | 0.0989 | 0.2978 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0251 | 0.0989 | 0.2978 |
Entamoeba histolytica | fructose-1,6-bisphosphate aldolase, putative | 0.0072 | 0.0007 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0251 | 0.0989 | 0.2978 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0251 | 0.0989 | 0.2978 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0251 | 0.0989 | 0.2978 |
Schistosoma mansoni | histamine h1 receptor | 0.0251 | 0.0989 | 0.2978 |
Plasmodium falciparum | 3',5'-cyclic nucleotide phosphodiesterase, putative | 0.0085 | 0.0079 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Brugia malayi | hypothetical protein | 0.0251 | 0.0989 | 0.3511 |
Echinococcus granulosus | serotonin receptor | 0.0251 | 0.0989 | 0.2978 |
Brugia malayi | Dopamine receptor protein 1 | 0.0251 | 0.0989 | 0.3511 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Onchocerca volvulus | 0.0251 | 0.0989 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Plasmodium falciparum | phosphodiesterase delta, putative | 0.0085 | 0.0079 | 0.5 |
Trichomonas vaginalis | cAMP-specific phosphodiesterase, putative | 0.0119 | 0.0263 | 0.7083 |
Brugia malayi | sulfakinin receptor protein | 0.0251 | 0.0989 | 0.3511 |
Onchocerca volvulus | 0.0251 | 0.0989 | 1 | |
Brugia malayi | Serotonin receptor | 0.0251 | 0.0989 | 0.3511 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0251 | 0.0989 | 0.2978 |
Echinococcus multilocularis | fmrfamide receptor | 0.0251 | 0.0989 | 0.2978 |
Echinococcus multilocularis | somatostatin receptor | 0.0251 | 0.0989 | 0.2978 |
Echinococcus granulosus | hypothetical protein | 0.0251 | 0.0989 | 0.2978 |
Brugia malayi | neuropeptide F receptor | 0.0251 | 0.0989 | 0.3511 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0251 | 0.0989 | 0.2978 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0251 | 0.0989 | 0.2978 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0251 | 0.0989 | 0.2978 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Echinococcus granulosus | neuropeptide s receptor | 0.0251 | 0.0989 | 0.2978 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0251 | 0.0989 | 0.2978 |
Brugia malayi | hypothetical protein | 0.0251 | 0.0989 | 0.3511 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative | 0.0085 | 0.0079 | 0.1969 |
Trichomonas vaginalis | cAMP/cGMP cyclic nucleotide phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0251 | 0.0989 | 0.2978 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0251 | 0.0989 | 0.2978 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0251 | 0.0989 | 0.2978 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0251 | 0.0989 | 0.2978 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0251 | 0.0989 | 0.2978 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0251 | 0.0989 | 0.2978 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0251 | 0.0989 | 1 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0251 | 0.0989 | 0.2978 |
Mycobacterium ulcerans | isocitrate lyase AceAb | 0.1898 | 1 | 0.5 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0251 | 0.0989 | 0.2978 |
Brugia malayi | Dopamine receptor protein 2 | 0.0251 | 0.0989 | 0.3511 |
Echinococcus multilocularis | serotonin receptor | 0.0251 | 0.0989 | 0.2978 |
Mycobacterium tuberculosis | Probable isocitrate lyase AceAa [first part] (isocitrase) (isocitratase) (Icl) | 0.1898 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0251 | 0.0989 | 0.2978 |
Schistosoma mansoni | opsin-like receptor | 0.0251 | 0.0989 | 0.2978 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0251 | 0.0989 | 0.2978 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0251 | 0.0989 | 0.2978 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0251 | 0.0989 | 0.2978 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0251 | 0.0989 | 0.2978 |
Giardia lamblia | Hypothetical protein | 0.0085 | 0.0079 | 0.0227 |
Echinococcus granulosus | sex peptide receptor | 0.0251 | 0.0989 | 0.2978 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0085 | 0.0079 | 0.1969 |
Onchocerca volvulus | 0.0251 | 0.0989 | 1 | |
Echinococcus granulosus | allatostatin A receptor | 0.0251 | 0.0989 | 0.2978 |
Plasmodium falciparum | cGMP-specific phosphodiesterase | 0.0085 | 0.0079 | 0.5 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0251 | 0.0989 | 0.2978 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Brugia malayi | follicle stimulating hormone receptor | 0.0251 | 0.0989 | 0.3511 |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0251 | 0.0989 | 0.2978 |
Loa Loa (eye worm) | PDE1B protein | 0.0085 | 0.0079 | 0.025 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0251 | 0.0989 | 0.2978 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0251 | 0.0989 | 0.2978 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0104 | 0.0184 | 0.4886 |
Plasmodium vivax | 3',5'-cyclic nucleotide phosphodiesterase, putative | 0.0085 | 0.0079 | 0.5 |
Schistosoma mansoni | amine GPCR | 0.0251 | 0.0989 | 0.2978 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0559 | 0.2673 | 0.8481 |
Brugia malayi | hypothetical protein | 0.0251 | 0.0989 | 0.3511 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0251 | 0.0989 | 0.3153 |
Brugia malayi | hypothetical protein | 0.0251 | 0.0989 | 0.3511 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0138 | 0.0369 | 1 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0251 | 0.0989 | 0.3511 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0251 | 0.0989 | 0.2978 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0251 | 0.0989 | 0.2978 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0251 | 0.0989 | 0.3153 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Schistosoma mansoni | opsin-like receptor | 0.0251 | 0.0989 | 0.2978 |
Schistosoma mansoni | biogenic amine receptor | 0.0251 | 0.0989 | 0.2978 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0251 | 0.0989 | 0.2978 |
Trichomonas vaginalis | cAMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Plasmodium falciparum | phosphodiesterase gamma, putative | 0.0085 | 0.0079 | 0.5 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0644 | 0.3137 | 1 |
Trichomonas vaginalis | cAMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Echinococcus granulosus | neuropeptide receptor | 0.0251 | 0.0989 | 0.2978 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0251 | 0.0989 | 0.3153 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Plasmodium vivax | 3',5'-cyclic nucleotide phosphodiesterase, putative | 0.0085 | 0.0079 | 0.5 |
Echinococcus granulosus | g protein coupled receptor | 0.0251 | 0.0989 | 0.2978 |
Echinococcus granulosus | fmrfamide receptor | 0.0251 | 0.0989 | 0.2978 |
Trichomonas vaginalis | cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative | 0.0119 | 0.0263 | 0.7083 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0251 | 0.0989 | 0.2978 |
Trichomonas vaginalis | cAMP-specific phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0085 | 0.0079 | 0.1969 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0644 | 0.3137 | 1 |
Loa Loa (eye worm) | calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase | 0.0085 | 0.0079 | 0.025 |
Echinococcus multilocularis | serotonin receptor | 0.0251 | 0.0989 | 0.2978 |
Echinococcus granulosus | subfamily M14A unassigned peptidase | 0.0085 | 0.008 | 0.0005 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0251 | 0.0989 | 0.2978 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Echinococcus granulosus | dual 3'5' cyclic AMP and GMP phosphodiesterase | 0.0138 | 0.0369 | 0.0948 |
Brugia malayi | Dopamine receptor | 0.0251 | 0.0989 | 0.3511 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0251 | 0.0989 | 0.2978 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0251 | 0.0989 | 0.2978 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0251 | 0.0989 | 0.2978 |
Onchocerca volvulus | 0.0251 | 0.0989 | 1 | |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0251 | 0.0989 | 0.3153 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Schistosoma mansoni | myosin xvIII | 0.0251 | 0.0989 | 0.2978 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0251 | 0.0989 | 0.2978 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Echinococcus multilocularis | sex peptide receptor | 0.0251 | 0.0989 | 0.2978 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Schistosoma mansoni | adenoreceptor | 0.0251 | 0.0989 | 0.2978 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.0079 | 0.025 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0251 | 0.0989 | 0.2978 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0251 | 0.0989 | 0.2978 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0085 | 0.0079 | 0.1969 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0251 | 0.0989 | 0.2978 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0644 | 0.3137 | 1 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0251 | 0.0989 | 0.2978 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Brugia malayi | G-protein coupled receptor | 0.0251 | 0.0989 | 0.3511 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Plasmodium falciparum | 3',5'-cyclic nucleotide phosphodiesterase, putative | 0.0085 | 0.0079 | 0.5 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0251 | 0.0989 | 0.2978 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0251 | 0.0989 | 0.2978 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0251 | 0.0989 | 0.2978 |
Schistosoma mansoni | biogenic amine receptor | 0.0251 | 0.0989 | 0.2978 |
Onchocerca volvulus | 0.0251 | 0.0989 | 1 | |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0251 | 0.0989 | 0.2978 |
Schistosoma mansoni | neuropeptide receptor | 0.0251 | 0.0989 | 0.2978 |
Schistosoma mansoni | hypothetical protein | 0.0251 | 0.0989 | 0.2978 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0251 | 0.0989 | 0.2978 |
Plasmodium vivax | phosphodiesterase gamma, putative | 0.0085 | 0.0079 | 0.5 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Brugia malayi | larval opioid receptor | 0.0251 | 0.0989 | 0.3511 |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0251 | 0.0989 | 0.2978 |
Echinococcus multilocularis | neuropeptide receptor | 0.0251 | 0.0989 | 0.2978 |
Brugia malayi | hypothetical protein | 0.0251 | 0.0989 | 0.3511 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0251 | 0.0989 | 0.2978 |
Trichomonas vaginalis | cGMP-inhibited 3,5-cyclic phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0251 | 0.0989 | 0.2978 |
Onchocerca volvulus | 0.0251 | 0.0989 | 1 | |
Schistosoma mansoni | amine GPCR | 0.0251 | 0.0989 | 0.2978 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0104 | 0.0184 | 0.4886 |
Echinococcus multilocularis | subfamily M14A unassigned peptidase | 0.0085 | 0.008 | 0.0005 |
Echinococcus granulosus | somatostatin receptor | 0.0251 | 0.0989 | 0.2978 |
Schistosoma mansoni | neuropeptide receptor | 0.0251 | 0.0989 | 0.2978 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0251 | 0.0989 | 0.3153 |
Schistosoma mansoni | microtubule-associated protein tau | 0.017 | 0.0543 | 0.1518 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0251 | 0.0989 | 0.2978 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0085 | 0.0079 | 0.1969 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0251 | 0.0989 | 0.2978 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0251 | 0.0989 | 0.2978 |
Brugia malayi | 3'5'-cyclic nucleotide phosphodiesterase family protein | 0.0104 | 0.0184 | 0.0406 |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Onchocerca volvulus | 0.0251 | 0.0989 | 1 | |
Brugia malayi | Melatonin receptor type 1A | 0.0251 | 0.0989 | 0.3511 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0251 | 0.0989 | 0.2978 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase R153.1, putative | 0.0559 | 0.2673 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Schistosoma mansoni | opsin-like receptor | 0.0251 | 0.0989 | 0.2978 |
Onchocerca volvulus | 0.0251 | 0.0989 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Plasmodium vivax | cyclic nucleotide phosphodiesterase, putative | 0.0085 | 0.0079 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0251 | 0.0989 | 0.2978 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0119 | 0.0263 | 0.6368 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0251 | 0.0989 | 0.3511 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0251 | 0.0989 | 0.3153 |
Schistosoma mansoni | camp/cgmp cyclic nucleotide phosphodiesterase | 0.0138 | 0.0369 | 0.0948 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0251 | 0.0989 | 0.2978 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0251 | 0.0989 | 0.2978 |
Trypanosoma brucei | cAMP-specific phosphodiesterase | 0.0138 | 0.0369 | 1 |
Brugia malayi | putative neuropeptide receptor | 0.0251 | 0.0989 | 0.3511 |
Onchocerca volvulus | 0.0251 | 0.0989 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0251 | 0.0989 | 0.2978 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0251 | 0.0989 | 0.2978 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0251 | 0.0989 | 0.2978 |
Brugia malayi | hypothetical protein | 0.0251 | 0.0989 | 0.3511 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0251 | 0.0989 | 0.2978 |
Echinococcus granulosus | microtubule associated protein 2 | 0.017 | 0.0543 | 0.1518 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0251 | 0.0989 | 0.2978 |
Schistosoma mansoni | amine GPCR | 0.0251 | 0.0989 | 0.2978 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0644 | 0.3137 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0251 | 0.0989 | 0.2978 |
Onchocerca volvulus | 0.0251 | 0.0989 | 1 | |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0251 | 0.0989 | 0.2978 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0251 | 0.0989 | 0.2978 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0104 | 0.0184 | 0.4886 |
Loa Loa (eye worm) | hypothetical protein | 0.0644 | 0.3137 | 1 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0251 | 0.0989 | 0.2978 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0251 | 0.0989 | 0.2978 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Onchocerca volvulus | 0.0251 | 0.0989 | 1 | |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0251 | 0.0989 | 0.2978 |
Onchocerca volvulus | 0.0251 | 0.0989 | 1 | |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0251 | 0.0989 | 0.2978 |
Brugia malayi | RE15519p | 0.0251 | 0.0989 | 0.3511 |
Echinococcus multilocularis | dual 3',5' cyclic AMP and GMP phosphodiesterase | 0.0138 | 0.0369 | 0.0948 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Echinococcus multilocularis | allatostatin A receptor | 0.0251 | 0.0989 | 0.2978 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Brugia malayi | hypothetical protein | 0.0251 | 0.0989 | 0.3511 |
Trichomonas vaginalis | cone cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0251 | 0.0989 | 0.3511 |
Trichomonas vaginalis | cAMP-specific phosphodiesterase, putative | 0.0138 | 0.0369 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0251 | 0.0989 | 0.2978 |
Echinococcus granulosus | g protein coupled receptor | 0.0251 | 0.0989 | 0.2978 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0085 | 0.0079 | 0.1969 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0644 | 0.3137 | 1 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0251 | 0.0989 | 0.3153 |
Trichomonas vaginalis | cGMP-inhibited 3,5-cyclic phosphodiesterase, putative | 0.0085 | 0.0079 | 0.1969 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0251 | 0.0989 | 0.2978 |
Echinococcus granulosus | orexin receptor type 2 | 0.0251 | 0.0989 | 0.2978 |
Onchocerca volvulus | 0.0251 | 0.0989 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.0989 | 0.3153 |
Echinococcus granulosus | g protein coupled receptor | 0.0251 | 0.0989 | 0.2978 |
Onchocerca volvulus | 0.0251 | 0.0989 | 1 | |
Giardia lamblia | CAMP-specific 3,5-cyclic phosphodiesterase 4B | 0.0644 | 0.3137 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | Inhibition of human plasma kallikrein at 55 uM | ChEMBL. | 17850059 | |
Activity (binding) | Inhibition of human spleen cathepsin D at 55 uM | ChEMBL. | 17850059 | |
Activity (binding) | Inhibition of pig kidney aminopeptidase M at 55 uM | ChEMBL. | 17850059 | |
Activity (binding) | Inhibition of human urokinase at 55 uM | ChEMBL. | 17850059 | |
Activity (binding) | Inhibition of human thrombin at 55 uM | ChEMBL. | 17850059 | |
Activity (binding) | 0 | Inhibition of pig kidney aminopeptidase M at 55 uM | ChEMBL. | 17850059 |
Activity (binding) | 0 | Inhibition of human spleen cathepsin D at 55 uM | ChEMBL. | 17850059 |
Activity (binding) | 0 | Inhibition of human plasma kallikrein at 55 uM | ChEMBL. | 17850059 |
Activity (binding) | 0 | Inhibition of human thrombin at 55 uM | ChEMBL. | 17850059 |
Activity (binding) | 0 | Inhibition of human pancreatic chymotrypsin at 55 uM | ChEMBL. | 17850059 |
Activity (binding) | 0 | Inhibition of human urokinase at 55 uM | ChEMBL. | 17850059 |
Ki (binding) | = 29900 nM | Inhibition of human NE | ChEMBL. | 17850059 |
Ki (binding) | = 29900 nM | Inhibition of human NE | ChEMBL. | 17850059 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.