Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | cathepsin CPC1 | 0.0073 | 0.1759 | 0.1307 |
Echinococcus multilocularis | cysteine protease | 0.0358 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0073 | 0.1759 | 0.1759 |
Entamoeba histolytica | cysteine protease, putative | 0.0189 | 0.51 | 0.4987 |
Trichomonas vaginalis | AGC family protein kinase | 0.0032 | 0.0578 | 0.0578 |
Loa Loa (eye worm) | fibroinase | 0.0358 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.1759 | 0.1307 |
Loa Loa (eye worm) | hypothetical protein | 0.0358 | 1 | 1 |
Plasmodium vivax | vivapain-3 | 0.0189 | 0.51 | 0.4987 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0358 | 1 | 1 |
Brugia malayi | cathepsin L precursor | 0.0073 | 0.1759 | 0.1307 |
Entamoeba histolytica | cysteine protease, putative | 0.0073 | 0.1759 | 0.1569 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0073 | 0.1759 | 0.1569 |
Leishmania major | cysteine peptidase A (CPA) | 0.0358 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0189 | 0.51 | 0.4987 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0358 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0115 | 0.2982 | 0.2597 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0073 | 0.1759 | 0.1569 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0189 | 0.51 | 0.4987 |
Onchocerca volvulus | 0.0358 | 1 | 1 | |
Entamoeba histolytica | cysteine protease, putative | 0.0189 | 0.51 | 0.4987 |
Entamoeba histolytica | cysteine protease, putative | 0.0189 | 0.51 | 0.4987 |
Plasmodium vivax | dipeptidyl aminopeptidase 3, putative | 0.0073 | 0.1759 | 0.1569 |
Echinococcus granulosus | cysteine protease | 0.0189 | 0.51 | 0.4991 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0073 | 0.1759 | 0.1569 |
Entamoeba histolytica | cysteine protease, putative | 0.0189 | 0.51 | 0.4987 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0358 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0358 | 1 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0358 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.0356 | 0.9954 | 0.9953 |
Giardia lamblia | Cathepsin L precursor | 0.0073 | 0.1759 | 0.3771 |
Giardia lamblia | Cathepsin B precursor | 0.0073 | 0.1759 | 0.3771 |
Plasmodium vivax | serine-repeat antigen 4 (SERA) | 0.0073 | 0.1759 | 0.1569 |
Echinococcus granulosus | cathepsin L | 0.0189 | 0.51 | 0.4991 |
Plasmodium falciparum | serine repeat antigen 8 | 0.0073 | 0.1759 | 0.1569 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0358 | 1 | 1 |
Giardia lamblia | Cathepsin L-like protease | 0.0073 | 0.1759 | 0.3771 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0189 | 0.51 | 0.4831 |
Onchocerca volvulus | 0.0358 | 1 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0358 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0242 | 0.6659 | 0.6659 |
Echinococcus multilocularis | serine threonine protein kinase nrc serine threonine protein kinase gad | 0.002 | 0.0225 | 0.0007 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0358 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0358 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0189 | 0.51 | 0.4987 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0358 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.1759 | 0.1307 |
Plasmodium vivax | dipeptidyl aminopeptidase 1, putative | 0.0073 | 0.1759 | 0.1569 |
Entamoeba histolytica | cysteine protease, putative | 0.0073 | 0.1759 | 0.1569 |
Giardia lamblia | Cathepsin B precursor | 0.0161 | 0.4294 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0358 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0358 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0189 | 0.51 | 0.48 |
Echinococcus granulosus | cathepsin b | 0.0356 | 0.9954 | 0.9953 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0358 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.0358 | 1 | 1 |
Toxoplasma gondii | cathepsin B | 0.0161 | 0.4294 | 0.3981 |
Echinococcus multilocularis | cathepsin L | 0.0073 | 0.1759 | 0.1575 |
Echinococcus granulosus | serine threonine protein kinase nrc | 0.002 | 0.0225 | 0.0007 |
Brugia malayi | Cathepsin L-like precursor | 0.0358 | 1 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0358 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase | 0.0073 | 0.1759 | 0.1759 |
Leishmania major | cathepsin L-like protease | 0.0358 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.2982 | 0.2597 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0073 | 0.1759 | 0.1759 |
Loa Loa (eye worm) | ctsf protein | 0.0358 | 1 | 1 |
Plasmodium falciparum | serine repeat antigen 1 | 0.0073 | 0.1759 | 0.1569 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0189 | 0.51 | 0.4987 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0073 | 0.1759 | 0.1307 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0073 | 0.1759 | 0.1759 |
Toxoplasma gondii | cathepsin CPC2 | 0.0073 | 0.1759 | 0.1307 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0358 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0358 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0358 | 1 | 1 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0073 | 0.1759 | 0.1307 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0189 | 0.51 | 0.4987 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0073 | 0.1759 | 0.1759 |
Giardia lamblia | Cathepsin L precursor | 0.0073 | 0.1759 | 0.3771 |
Leishmania major | cathepsin L-like protease | 0.0358 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0073 | 0.1759 | 0.3771 |
Loa Loa (eye worm) | hypothetical protein | 0.0242 | 0.6659 | 0.6476 |
Echinococcus granulosus | cathepsin L | 0.0073 | 0.1759 | 0.1575 |
Trypanosoma cruzi | Protein kinase B | 0.0022 | 0.0283 | 0.0059 |
Leishmania major | cathepsin L-like protease | 0.0358 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0161 | 0.4294 | 0.4128 |
Onchocerca volvulus | 0.0358 | 1 | 1 | |
Entamoeba histolytica | cysteine protease, putative | 0.0189 | 0.51 | 0.4987 |
Brugia malayi | cathepsin L-like precursor | 0.0242 | 0.6659 | 0.6476 |
Plasmodium vivax | serine-repeat antigen 5 (SERA) | 0.0073 | 0.1759 | 0.1569 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0115 | 0.2982 | 0.282 |
Onchocerca volvulus | 0.0358 | 1 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0358 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0189 | 0.51 | 0.4987 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.1759 | 0.1307 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0073 | 0.1759 | 0.1519 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0189 | 0.51 | 0.4957 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0242 | 0.6659 | 0.6582 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0358 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0032 | 0.0578 | 0.0578 |
Loa Loa (eye worm) | hypothetical protein | 0.0356 | 0.9954 | 0.9952 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0022 | 0.0283 | 0.0059 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.0356 | 0.9954 | 0.9952 |
Onchocerca volvulus | 0.0358 | 1 | 1 | |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0358 | 1 | 1 |
Plasmodium vivax | unspecified product | 0.0115 | 0.2982 | 0.282 |
Loa Loa (eye worm) | hypothetical protein | 0.0242 | 0.6659 | 0.6476 |
Loa Loa (eye worm) | cathepsin B | 0.0161 | 0.4294 | 0.3981 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0073 | 0.1759 | 0.3771 |
Brugia malayi | Cathepsin L-like precursor | 0.0242 | 0.6659 | 0.6476 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0358 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0189 | 0.51 | 0.4987 |
Echinococcus multilocularis | cathepsin b | 0.0356 | 0.9954 | 0.9953 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0358 | 1 | 1 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0115 | 0.2982 | 0.2597 |
Giardia lamblia | Cysteine protease | 0.0073 | 0.1759 | 0.3771 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0358 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0073 | 0.1759 | 0.3771 |
Giardia lamblia | Hypothetical protein | 0.0073 | 0.1759 | 0.3771 |
Entamoeba histolytica | protein kinase, putative | 0.003 | 0.052 | 0.0302 |
Giardia lamblia | Hypothetical protein | 0.0073 | 0.1759 | 0.3771 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0189 | 0.51 | 0.4987 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0032 | 0.0578 | 0.0061 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0189 | 0.51 | 0.4987 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0073 | 0.1759 | 0.1307 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0358 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0358 | 1 | 1 |
Giardia lamblia | Cathepsin L-like protease | 0.0073 | 0.1759 | 0.3771 |
Plasmodium vivax | serine-repeat antigen 3 (SERA) | 0.0073 | 0.1759 | 0.1569 |
Trichomonas vaginalis | AGC family protein kinase | 0.0032 | 0.0578 | 0.0578 |
Giardia lamblia | Cysteine protease | 0.0073 | 0.1759 | 0.3771 |
Echinococcus multilocularis | cathepsin b | 0.0356 | 0.9954 | 0.9953 |
Plasmodium falciparum | dipeptidyl aminopeptidase 1 | 0.0073 | 0.1759 | 0.1569 |
Schistosoma mansoni | cathepsin C | 0.0073 | 0.1759 | 0.1519 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0358 | 1 | 1 |
Plasmodium vivax | vivapain-1 | 0.0189 | 0.51 | 0.4987 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0358 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0358 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0242 | 0.6659 | 0.6562 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0358 | 1 | 1 |
Plasmodium vivax | serine-repeat antigen 4 (SERA), putative | 0.0073 | 0.1759 | 0.1569 |
Brugia malayi | fibroinase precursor | 0.0073 | 0.1759 | 0.1307 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0073 | 0.1759 | 0.1759 |
Brugia malayi | cahepsin L-like non-peptiedase homolog | 0.0073 | 0.1759 | 0.1307 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or H-like cysteine peptidase | 0.0073 | 0.1759 | 0.1759 |
Entamoeba histolytica | hypothetical protein | 0.0073 | 0.1759 | 0.1569 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0358 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0358 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0358 | 1 | 1 |
Schistosoma mansoni | cathepsin S (C01 family) | 0.0073 | 0.1759 | 0.1519 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.2982 | 0.2597 |
Brugia malayi | Protein kinase domain containing protein | 0.0032 | 0.0578 | 0.0061 |
Echinococcus multilocularis | rac serine:threonine kinase | 0.0022 | 0.0283 | 0.0066 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0073 | 0.1759 | 0.1759 |
Entamoeba histolytica | cysteine protease, putative | 0.0073 | 0.1759 | 0.1569 |
Trichomonas vaginalis | AGC family protein kinase | 0.0032 | 0.0578 | 0.0578 |
Loa Loa (eye worm) | cysteine protease | 0.0358 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0032 | 0.0578 | 0.0578 |
Plasmodium vivax | unspecified product | 0.0189 | 0.51 | 0.4987 |
Leishmania major | cathepsin L-like protease | 0.0358 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.0358 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0358 | 1 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0242 | 0.6659 | 0.6584 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0356 | 0.9954 | 0.9953 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0358 | 1 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0032 | 0.0578 | 0.0361 |
Trichomonas vaginalis | AGC family protein kinase | 0.0032 | 0.0578 | 0.0578 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0358 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0358 | 1 | 1 |
Giardia lamblia | Cathepsin L precursor | 0.0073 | 0.1759 | 0.3771 |
Giardia lamblia | Cysteine protease | 0.0073 | 0.1759 | 0.3771 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0356 | 0.9954 | 0.9953 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0073 | 0.1759 | 0.1759 |
Giardia lamblia | Cathepsin L precursor | 0.0073 | 0.1759 | 0.3771 |
Leishmania major | cathepsin L-like protease | 0.0358 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0161 | 0.4294 | 1 |
Plasmodium falciparum | dipeptidyl aminopeptidase 3 | 0.0073 | 0.1759 | 0.1569 |
Giardia lamblia | Cathepsin L precursor | 0.0073 | 0.1759 | 0.3771 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0073 | 0.1759 | 0.3771 |
Leishmania major | cathepsin L-like protease | 0.0358 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0358 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0358 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0358 | 1 | 1 |
Giardia lamblia | Encystation-specific protease | 0.0073 | 0.1759 | 0.3771 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0073 | 0.1759 | 0.1759 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0358 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0073 | 0.1759 | 0.1759 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin H-like cysteine peptidase | 0.0073 | 0.1759 | 0.1759 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0358 | 1 | 1 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0073 | 0.1759 | 0.1569 |
Entamoeba histolytica | protein kinase, putative | 0.0032 | 0.0578 | 0.0361 |
Entamoeba histolytica | cysteine protease, putative | 0.0073 | 0.1759 | 0.1569 |
Schistosoma mansoni | cathepsin B (C01 family) | 0.0073 | 0.1759 | 0.1519 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0358 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0073 | 0.1759 | 0.1759 |
Plasmodium falciparum | serine repeat antigen 7 | 0.0073 | 0.1759 | 0.1569 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0073 | 0.1759 | 0.1759 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0073 | 0.1759 | 0.1519 |
Toxoplasma gondii | preprocathepsin c precursor, putative | 0.0073 | 0.1759 | 0.1307 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0189 | 0.51 | 0.4987 |
Loa Loa (eye worm) | cysteine proteinase cathepsin Z | 0.0073 | 0.1759 | 0.1307 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0115 | 0.2982 | 0.2597 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0022 | 0.0283 | 0.0059 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0358 | 1 | 1 |
Plasmodium falciparum | serine repeat antigen 4 | 0.0073 | 0.1759 | 0.1569 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0358 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0189 | 0.51 | 0.4987 |
Schistosoma mansoni | subfamily C1A non-peptidase homologue (C01 family) | 0.0073 | 0.1759 | 0.1519 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0358 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0115 | 0.2982 | 0.2597 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0073 | 0.1759 | 0.1569 |
Entamoeba histolytica | cysteine protease, putative | 0.0073 | 0.1759 | 0.1569 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0073 | 0.1759 | 0.1519 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0358 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0189 | 0.51 | 0.4987 |
Giardia lamblia | Cysteine protease | 0.0073 | 0.1759 | 0.3771 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0189 | 0.51 | 0.48 |
Trypanosoma cruzi | cysteine protease, putative | 0.0189 | 0.51 | 0.4987 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0115 | 0.2982 | 0.2597 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0358 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0358 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0073 | 0.1759 | 0.1759 |
Brugia malayi | cathepsin L-like cysteine proteinase | 0.0073 | 0.1759 | 0.1307 |
Plasmodium falciparum | dipeptidyl aminopeptidase 2 | 0.0073 | 0.1759 | 0.1569 |
Entamoeba histolytica | cysteine protease, putative | 0.0073 | 0.1759 | 0.1569 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0073 | 0.1759 | 0.1307 |
Plasmodium falciparum | serine repeat antigen 2 | 0.0073 | 0.1759 | 0.1569 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0073 | 0.1759 | 0.1307 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.1759 | 0.1307 |
Giardia lamblia | Cathepsin B precursor | 0.0073 | 0.1759 | 0.3771 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0358 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0073 | 0.1759 | 0.1759 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0115 | 0.2982 | 0.282 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0242 | 0.6659 | 0.6659 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.1759 | 0.1307 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0189 | 0.51 | 0.4957 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0356 | 0.9954 | 0.9953 |
Giardia lamblia | Cathepsin B-like cysteine proteinase 3 precursor | 0.0073 | 0.1759 | 0.3771 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0242 | 0.6659 | 0.6476 |
Echinococcus granulosus | serine/threonine protein kinase | 0.0022 | 0.0283 | 0.0066 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0073 | 0.1759 | 0.1519 |
Plasmodium vivax | unspecified product | 0.0073 | 0.1759 | 0.1569 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0161 | 0.4294 | 0.4294 |
Brugia malayi | Cathepsin L-like precursor | 0.0242 | 0.6659 | 0.6476 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0073 | 0.1759 | 0.1569 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0189 | 0.51 | 0.51 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0358 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0189 | 0.51 | 0.4987 |
Trichomonas vaginalis | AGC family protein kinase | 0.0032 | 0.0578 | 0.0578 |
Loa Loa (eye worm) | hypothetical protein | 0.0242 | 0.6659 | 0.6476 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0073 | 0.1759 | 0.1519 |
Echinococcus granulosus | cathepsin l1 | 0.0358 | 1 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0189 | 0.51 | 0.4987 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase | 0.002 | 0.0225 | 0.0007 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0358 | 1 | 1 |
Schistosoma mansoni | cathepsin s | 0.0115 | 0.2982 | 0.2777 |
Giardia lamblia | Cathepsin B precursor | 0.0073 | 0.1759 | 0.3771 |
Giardia lamblia | Dipeptidyl-peptidase I precursor | 0.0073 | 0.1759 | 0.3771 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0358 | 1 | 1 |
Plasmodium falciparum | serine repeat antigen 6 | 0.0073 | 0.1759 | 0.1569 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0073 | 0.1759 | 0.1569 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0189 | 0.51 | 0.4987 |
Onchocerca volvulus | Cathepsin L homolog | 0.0358 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0358 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0073 | 0.1759 | 0.1307 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0358 | 1 | 1 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0189 | 0.51 | 0.4991 |
Plasmodium falciparum | serine repeat antigen 3 | 0.0073 | 0.1759 | 0.1569 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0189 | 0.51 | 0.4987 |
Toxoplasma gondii | cathepsin CPL | 0.0358 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0073 | 0.1759 | 0.1759 |
Plasmodium vivax | dipeptidyl aminopeptidase 2, putative | 0.0073 | 0.1759 | 0.1569 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0073 | 0.1759 | 0.1307 |
Onchocerca volvulus | 0.0358 | 1 | 1 | |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0356 | 0.9954 | 0.9953 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.1759 | 0.1307 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0189 | 0.51 | 0.4987 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0189 | 0.51 | 0.4831 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0358 | 1 | 1 |
Schistosoma mansoni | dipeptidyl-peptidase I (C01 family) | 0.0073 | 0.1759 | 0.1519 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0358 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0189 | 0.51 | 0.4987 |
Plasmodium falciparum | serine repeat antigen 9 | 0.0073 | 0.1759 | 0.1569 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0358 | 1 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0073 | 0.1759 | 0.1307 |
Echinococcus multilocularis | cathepsin L | 0.0189 | 0.51 | 0.4991 |
Onchocerca volvulus | 0.0242 | 0.6659 | 0.5946 | |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0358 | 1 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0189 | 0.51 | 0.4957 |
Giardia lamblia | Cathepsin L precursor | 0.0073 | 0.1759 | 0.3771 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0073 | 0.1759 | 0.1519 |
Giardia lamblia | Cathepsin B precursor | 0.0161 | 0.4294 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0358 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0358 | 1 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0356 | 0.9954 | 0.9953 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0073 | 0.1759 | 0.1519 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0358 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0358 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0358 | 1 | 1 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0073 | 0.1759 | 0.1569 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0161 | 0.4294 | 0.4162 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0189 | 0.51 | 0.51 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0358 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0161 | 0.4294 | 0.3944 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin F-like cysteine peptidase | 0.0073 | 0.1759 | 0.1759 |
Brugia malayi | Cathepsin L-like precursor | 0.0358 | 1 | 1 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0022 | 0.0283 | 0.0059 |
Onchocerca volvulus | 0.0358 | 1 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0358 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0242 | 0.6659 | 0.6582 |
Plasmodium vivax | serine-repeat antigen 2 (SERA) | 0.0073 | 0.1759 | 0.1569 |
Plasmodium falciparum | serine repeat antigen 5 | 0.0073 | 0.1759 | 0.1569 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0358 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0073 | 0.1759 | 0.1759 |
Entamoeba histolytica | cysteine protease, putative | 0.0189 | 0.51 | 0.4987 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | = 0.00006 M kg-1 | Analgesic activity in mice by using hot plate method | ChEMBL. | 6312044 |
ED50 (functional) | = 0.00006 M kg-1 | Analgesic activity in mice by using hot plate method | ChEMBL. | 6312044 |
Relative potency (functional) | = 40.5 | Inhibition of electrically evoked twitches in guinea pig ileum relative to morphine. | ChEMBL. | 6312044 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.