Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0034 | 0.012 | 0.012 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Brugia malayi | aspartic protease BmAsp-2, identical | 0.0034 | 0.012 | 0.0246 |
Brugia malayi | hypothetical protein | 0.0058 | 0.0308 | 0.063 |
Trypanosoma brucei | ribonucleoside-diphosphate reductase small chain | 0.0138 | 0.0931 | 0.1837 |
Echinococcus multilocularis | cathepsin d (lysosomal aspartyl protease) | 0.0034 | 0.012 | 0.0238 |
Plasmodium vivax | plasmepsin V, putative | 0.0034 | 0.012 | 0.0146 |
Trichomonas vaginalis | ribonucleoside-diphosphate reductase alpha chain, putative | 0.0599 | 0.4513 | 1 |
Schistosoma mansoni | site-1 peptidase (S08 family) | 0.005 | 0.0246 | 0.0246 |
Brugia malayi | eukaryotic initiation factor 4A | 0.0024 | 0.0042 | 0.0085 |
Trypanosoma cruzi | ribonucleoside-diphosphate reductase large chain, putative | 0.0647 | 0.4885 | 1 |
Trypanosoma brucei | serine peptidase, clan SB, family S8-like protein | 0.005 | 0.0246 | 0.0422 |
Plasmodium falciparum | plasmepsin VIII, putative | 0.0034 | 0.012 | 0.0146 |
Trypanosoma brucei | ribonucleoside-diphosphate reductase small chain | 0.0138 | 0.0931 | 0.1837 |
Toxoplasma gondii | subtilisin SUB8 | 0.005 | 0.0246 | 0.038 |
Plasmodium vivax | aspartyl proteinase, putative | 0.0034 | 0.012 | 0.0146 |
Trichomonas vaginalis | conserved hypothetical protein | 0.005 | 0.0246 | 0.0457 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Mycobacterium tuberculosis | Probable ribonucleoside-diphosphate reductase (large subunit) NrdZ (ribonucleotide reductase) | 0.0215 | 0.1531 | 0.3331 |
Schistosoma mansoni | family A2 unassigned peptidase (A02 family) | 0.0237 | 0.1701 | 0.1701 |
Trichomonas vaginalis | conserved hypothetical protein | 0.005 | 0.0246 | 0.0457 |
Echinococcus multilocularis | ribonucleoside diphosphate reductase subunit | 0.0138 | 0.0931 | 0.1844 |
Brugia malayi | Subtilase family protein | 0.005 | 0.0246 | 0.0503 |
Trypanosoma cruzi | subtilisin-like serine peptidase, putative | 0.005 | 0.0246 | 0.0422 |
Echinococcus multilocularis | kelch ECH associated protein 1 | 0.0092 | 0.0573 | 0.1134 |
Loa Loa (eye worm) | lethal(1)discs large-1 tumor suppressor | 0.0022 | 0.0031 | 0.0064 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Trypanosoma brucei | subtilisin peptidase | 0.005 | 0.0246 | 0.0422 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0034 | 0.012 | 0.012 |
Echinococcus granulosus | adam | 0.0058 | 0.0308 | 0.0609 |
Toxoplasma gondii | subtilisin SUB9 | 0.005 | 0.0246 | 0.038 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0034 | 0.012 | 0.012 |
Toxoplasma gondii | aspartyl protease ASP3 | 0.0034 | 0.012 | 0.0146 |
Brugia malayi | angiogenesis inhibito | 0.0026 | 0.0059 | 0.012 |
Brugia malayi | ADAMTS-like protease | 0.0026 | 0.0059 | 0.012 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0034 | 0.012 | 0.012 |
Schistosoma mansoni | hypothetical protein | 0.0053 | 0.0272 | 0.0272 |
Trypanosoma cruzi | subtilisin-like serine peptidase, putative | 0.005 | 0.0246 | 0.0422 |
Echinococcus multilocularis | 0.005 | 0.0246 | 0.0487 | |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0034 | 0.012 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0059 | 0.012 |
Loa Loa (eye worm) | subtilase | 0.005 | 0.0246 | 0.0503 |
Echinococcus multilocularis | neuroendocrine convertase 2 | 0.005 | 0.0246 | 0.0487 |
Plasmodium falciparum | subtilisin-like protease 2 | 0.005 | 0.0246 | 0.038 |
Echinococcus granulosus | Bcl 2 ous antagonist:killer | 0.0053 | 0.0272 | 0.0538 |
Echinococcus multilocularis | Furin 1 | 0.005 | 0.0246 | 0.0487 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0246 | 0.0503 |
Mycobacterium tuberculosis | Probable membrane-anchored mycosin MycP3 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-3) | 0.005 | 0.0246 | 0.0457 |
Schistosoma mansoni | site-1 peptidase (S08 family) | 0.005 | 0.0246 | 0.0246 |
Trichomonas vaginalis | conserved hypothetical protein | 0.005 | 0.0246 | 0.0457 |
Mycobacterium leprae | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (ALPHA CHAIN) NRDE (RIBONUCLEOTIDE REDUCTASE SMALL SUBUNIT) (R1F PROTEIN) | 0.0599 | 0.4513 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.012 | 0.0246 |
Echinococcus multilocularis | adam | 0.0058 | 0.0308 | 0.0609 |
Schistosoma mansoni | memapsin-2 (A01 family) | 0.0841 | 0.6399 | 0.6399 |
Mycobacterium tuberculosis | Probable proline rich membrane-anchored mycosin MycP5 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-5) | 0.005 | 0.0246 | 0.0457 |
Mycobacterium ulcerans | membrane-anchored mycosin MycP3 | 0.005 | 0.0246 | 0.0058 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0034 | 0.012 | 0.012 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.0024 | 0.0042 | 0.0042 |
Leishmania major | ribonucleoside-diphosphate reductase small chain, putative | 0.0138 | 0.0931 | 0.1837 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Toxoplasma gondii | subtilisin SUB1 | 0.0716 | 0.5422 | 1 |
Loa Loa (eye worm) | guanylate kinase | 0.002 | 0.001 | 0.002 |
Plasmodium vivax | plasmepsin IV, putative | 0.0034 | 0.012 | 0.0146 |
Echinococcus granulosus | kelch ECH associated protein 1 like | 0.0092 | 0.0573 | 0.1134 |
Echinococcus multilocularis | EGFP:Bcl2 fusion protein | 0.0668 | 0.505 | 1 |
Brugia malayi | celfurPC protein | 0.005 | 0.0246 | 0.0503 |
Loa Loa (eye worm) | aspartic protease BmAsp-2 | 0.0034 | 0.012 | 0.0246 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Toxoplasma gondii | ribonucleoside-diphosphate reductase large chain | 0.0647 | 0.4885 | 0.9003 |
Mycobacterium tuberculosis | Probable alanine and proline rich membrane-anchored mycosin MycP2 (serine protease) (subtilisin-like protease) (subtilase-like) | 0.005 | 0.0246 | 0.0457 |
Mycobacterium leprae | PROBABLE PROLINE RICH MEMBRANE-ANCHORED MYCOSIN MYCP5 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-5) | 0.005 | 0.0246 | 0.0058 |
Echinococcus granulosus | subfamily M12B unassigned peptidase | 0.0044 | 0.0202 | 0.0399 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Brugia malayi | endoprotease bli-4 precursor | 0.005 | 0.0246 | 0.0503 |
Toxoplasma gondii | subtilisin SUB11 | 0.005 | 0.0246 | 0.038 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Echinococcus granulosus | furin | 0.005 | 0.0246 | 0.0487 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Brugia malayi | Guanylate kinase family protein | 0.0026 | 0.006 | 0.0123 |
Echinococcus granulosus | membrane bound transcription factor site 1 | 0.005 | 0.0246 | 0.0487 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0202 | 0.0413 |
Mycobacterium leprae | Possible secreted protease | 0.005 | 0.0246 | 0.0058 |
Giardia lamblia | Translation initiation factor eIF-4A, putative | 0.0024 | 0.0042 | 0.5 |
Echinococcus granulosus | eukaryotic initiation factor 4A III | 0.0024 | 0.0042 | 0.0082 |
Plasmodium vivax | ribonucleotide reductase small subunit, putative | 0.0047 | 0.0221 | 0.0334 |
Mycobacterium leprae | PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) | 0.005 | 0.0246 | 0.0058 |
Schistosoma mansoni | tripeptidyl-peptidase II (S08 family) | 0.005 | 0.0246 | 0.0246 |
Toxoplasma gondii | subtilisin SUB2 | 0.005 | 0.0246 | 0.038 |
Mycobacterium ulcerans | ribonucleotide-diphosphate reductase subunit alpha | 0.0599 | 0.4513 | 1 |
Chlamydia trachomatis | ribonucleoside-diphosphate reductase subunit alpha | 0.0647 | 0.4885 | 1 |
Plasmodium vivax | aspartyl proteinase, putative | 0.0034 | 0.012 | 0.0146 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0034 | 0.012 | 0.012 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.0042 | 0.0085 |
Brugia malayi | Hypothetical subtilase-type proteinase F21H12.6 in chromosome II | 0.005 | 0.0246 | 0.0503 |
Echinococcus granulosus | kelch ECH associated protein 1 | 0.0092 | 0.0573 | 0.1134 |
Schistosoma mansoni | subfamily S8B non-peptidase homologue (S08 family) | 0.005 | 0.0246 | 0.0246 |
Brugia malayi | Membrane-bound transcription factor site-1 protease precursor | 0.005 | 0.0246 | 0.0503 |
Mycobacterium tuberculosis | Ribonucleoside-diphosphate reductase (alpha chain) NrdE (ribonucleotide reductase small subunit) (R1F protein) | 0.0599 | 0.4513 | 1 |
Treponema pallidum | ribonucleotide-diphosphate reductase subunit alpha | 0.0647 | 0.4885 | 1 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Trichomonas vaginalis | Clan AA, family A1, cathepsin D-like aspartic peptidase | 0.0034 | 0.012 | 0.0176 |
Schistosoma mansoni | subfamily M12B unassigned peptidase (M12 family) | 0.0044 | 0.0202 | 0.0202 |
Echinococcus granulosus | disks large 3 | 0.0024 | 0.0041 | 0.0082 |
Loa Loa (eye worm) | apoptosis regulator protein | 0.0053 | 0.0272 | 0.0557 |
Plasmodium falciparum | plasmepsin III | 0.0034 | 0.012 | 0.0146 |
Echinococcus granulosus | ribonucleoside diphosphate reductase subunit | 0.0138 | 0.0931 | 0.1844 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.012 | 0.0246 |
Loa Loa (eye worm) | ribonucleoside-diphosphate reductase large subunit | 0.0647 | 0.4885 | 1 |
Loa Loa (eye worm) | proprotein convertase 2 | 0.005 | 0.0246 | 0.0503 |
Schistosoma mansoni | adam (A disintegrin and metalloprotease | 0.0058 | 0.0308 | 0.0308 |
Echinococcus multilocularis | Bcl 2 ous antagonist:killer | 0.0053 | 0.0272 | 0.0538 |
Leishmania major | ribonucleoside-diphosphate reductase small chain, putative | 0.0138 | 0.0931 | 0.1837 |
Echinococcus granulosus | Furin 1 | 0.005 | 0.0246 | 0.0487 |
Loa Loa (eye worm) | reprolysin | 0.0044 | 0.0202 | 0.0413 |
Echinococcus multilocularis | subfamily M12B unassigned peptidase | 0.0044 | 0.0202 | 0.0399 |
Trypanosoma brucei | ribonucleoside-diphosphate reductase large chain | 0.0647 | 0.4885 | 1 |
Plasmodium falciparum | plasmepsin II | 0.0034 | 0.012 | 0.0146 |
Trypanosoma brucei | ribonucleoside-diphosphate reductase small chain | 0.0138 | 0.0931 | 0.1837 |
Toxoplasma gondii | aspartyl protease ASP1 | 0.0034 | 0.012 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.012 | 0.0246 |
Schistosoma mansoni | subfamily S8B unassigned peptidase (S08 family) | 0.005 | 0.0246 | 0.0246 |
Leishmania major | subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0422 |
Plasmodium falciparum | ribonucleoside-diphosphate reductase large subunit, putative | 0.0647 | 0.4885 | 0.9003 |
Mycobacterium ulcerans | transcriptional regulator NrdR | 0.0048 | 0.023 | 0.002 |
Echinococcus granulosus | EGFP:Bcl2 fusion protein | 0.0668 | 0.505 | 1 |
Brugia malayi | Apoptosis regulator proteins, Bcl-2 family protein | 0.0053 | 0.0272 | 0.0557 |
Echinococcus multilocularis | membrane bound transcription factor site 1 | 0.005 | 0.0246 | 0.0487 |
Brugia malayi | hypothetical protein | 0.0034 | 0.012 | 0.0246 |
Brugia malayi | proprotein convertase 2 | 0.005 | 0.0246 | 0.0503 |
Echinococcus multilocularis | disks large 3 | 0.0024 | 0.0041 | 0.0082 |
Brugia malayi | aspartic protease BmAsp-1, identical | 0.0034 | 0.012 | 0.0246 |
Loa Loa (eye worm) | aspartic protease BmAsp-1 | 0.0034 | 0.012 | 0.0246 |
Echinococcus granulosus | proprotein convertase subtilisin:kexin type 5 | 0.005 | 0.0246 | 0.0487 |
Schistosoma mansoni | bcl-2 homologous antagonist/killer (bak) | 0.0053 | 0.0272 | 0.0272 |
Trichomonas vaginalis | conserved hypothetical protein | 0.005 | 0.0246 | 0.0457 |
Onchocerca volvulus | 0.0034 | 0.012 | 0.384 | |
Schistosoma mansoni | hypothetical protein | 0.0053 | 0.0272 | 0.0272 |
Plasmodium vivax | aspartyl protease, putative | 0.0034 | 0.012 | 0.0146 |
Echinococcus granulosus | eukaryotic initiation factor 4A | 0.0024 | 0.0042 | 0.0082 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Schistosoma mansoni | furin-1 (S08 family) | 0.005 | 0.0246 | 0.0246 |
Entamoeba histolytica | DEAD/DEAH box helicase, putative | 0.0024 | 0.0042 | 0.5 |
Echinococcus granulosus | ribonucleoside diphosphate reductase large | 0.0647 | 0.4885 | 0.9673 |
Chlamydia trachomatis | ribonucleoside-diphosphate reductase subunit beta | 0.0138 | 0.0931 | 0.1506 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Echinococcus multilocularis | Peptidase S8 S53, subtilisin kexin sedolisin | 0.005 | 0.0246 | 0.0487 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Echinococcus granulosus | kelch ECH associated protein 1 like | 0.0092 | 0.0573 | 0.1134 |
Brugia malayi | Pepsin A precursor | 0.0034 | 0.012 | 0.0246 |
Brugia malayi | ribonucleotide reductase 2 | 0.0138 | 0.0931 | 0.1906 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Trypanosoma cruzi | ribonucleoside-diphosphate reductase small chain, putative | 0.0138 | 0.0931 | 0.1837 |
Schistosoma mansoni | apoptosis regulator bax | 0.0053 | 0.0272 | 0.0272 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.0024 | 0.0042 | 0.0042 |
Loa Loa (eye worm) | aspartyl protease 6 | 0.0034 | 0.012 | 0.0246 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Schistosoma mansoni | cell polarity protein | 0.0024 | 0.0041 | 0.0041 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0034 | 0.012 | 0.012 |
Brugia malayi | hypothetical protein | 0.0034 | 0.012 | 0.0246 |
Mycobacterium tuberculosis | Ribonucleoside-diphosphate reductase (beta chain) NrdB (ribonucleotide reductase small chain) | 0.0138 | 0.0931 | 0.199 |
Schistosoma mansoni | hypothetical protein | 0.0092 | 0.0575 | 0.0575 |
Mycobacterium ulcerans | membrane-anchored serine protease (mycosin), MycP4 | 0.005 | 0.0246 | 0.0058 |
Plasmodium vivax | ribonucleoside-diphosphate reductase large chain, putative | 0.0647 | 0.4885 | 0.9003 |
Plasmodium vivax | aspartyl protease, putative | 0.0034 | 0.012 | 0.0146 |
Plasmodium falciparum | plasmepsin VII | 0.0034 | 0.012 | 0.0146 |
Toxoplasma gondii | aspartyl proteinase (eimepsin), putative | 0.0034 | 0.012 | 0.0146 |
Toxoplasma gondii | subtilisin SUB10 | 0.005 | 0.0246 | 0.038 |
Plasmodium falciparum | ribonucleoside-diphosphate reductase small chain, putative | 0.0047 | 0.0221 | 0.0334 |
Mycobacterium tuberculosis | Probable transcriptional regulatory protein NrdR | 0.0048 | 0.023 | 0.0422 |
Toxoplasma gondii | ribonucleoside-diphosphate reductase small subunit | 0.0138 | 0.0931 | 0.1654 |
Echinococcus multilocularis | kelch ECH associated protein 1 | 0.0092 | 0.0573 | 0.1134 |
Brugia malayi | ribonucleoside-diphosphate reductase large chain, putative | 0.0647 | 0.4885 | 1 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0034 | 0.012 | 0.012 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Onchocerca volvulus | 0.005 | 0.0246 | 1 | |
Mycobacterium ulcerans | proline rich membrane-anchored mycosin MycP5 | 0.005 | 0.0246 | 0.0058 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0246 | 0.0503 |
Toxoplasma gondii | subtilisin SUB4 | 0.005 | 0.0246 | 0.038 |
Trypanosoma cruzi | ribonucleoside-diphosphate reductase small chain, putative | 0.0138 | 0.0931 | 0.1837 |
Echinococcus granulosus | cathepsin d lysosomal aspartyl protease | 0.0034 | 0.012 | 0.0238 |
Echinococcus multilocularis | eukaryotic initiation factor 4A | 0.0024 | 0.0042 | 0.0082 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Wolbachia endosymbiont of Brugia malayi | ribonucleotide-diphosphate reductase subunit alpha | 0.0599 | 0.4513 | 1 |
Toxoplasma gondii | subtilisin SUB7 | 0.005 | 0.0246 | 0.038 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Leishmania major | ribonucleoside-diphosphate reductase large chain, putative | 0.0647 | 0.4885 | 1 |
Echinococcus multilocularis | ribonucleoside diphosphate reductase large | 0.0647 | 0.4885 | 0.9673 |
Mycobacterium leprae | conserved hypothetical protein | 0.0048 | 0.023 | 0.002 |
Plasmodium vivax | subtilisin-like protease 1 | 0.0716 | 0.5422 | 1 |
Echinococcus multilocularis | Kelch repeat type 1 | 0.0092 | 0.0575 | 0.1138 |
Toxoplasma gondii | subtilisin SUB6 | 0.005 | 0.0246 | 0.038 |
Trypanosoma cruzi | serine peptidase, clan SB, family S8-like protein | 0.005 | 0.0246 | 0.0422 |
Brugia malayi | neuroendocrine convertase 1 precursor | 0.005 | 0.0246 | 0.0503 |
Plasmodium falciparum | ribonucleoside-diphosphate reductase small chain, putative | 0.0138 | 0.0931 | 0.1654 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Trypanosoma brucei | ribonucleoside-diphosphate reductase small chain | 0.0047 | 0.0221 | 0.0371 |
Echinococcus granulosus | peptidase s8 s53 subtilisin kexin sedolisin | 0.005 | 0.0246 | 0.0487 |
Brugia malayi | Reprolysin | 0.0026 | 0.0059 | 0.012 |
Mycobacterium tuberculosis | Ribonucleoside-diphosphate reductase (beta chain) NrdF1 (ribonucleotide reductase small subunit) (R2F protein) | 0.0138 | 0.0931 | 0.199 |
Brugia malayi | Eukaryotic aspartyl protease family protein | 0.0034 | 0.012 | 0.0246 |
Toxoplasma gondii | subtilisin SUB12 | 0.005 | 0.0246 | 0.038 |
Toxoplasma gondii | aspartyl protease | 0.0034 | 0.012 | 0.0146 |
Schistosoma mansoni | ribonucleoside-diphosphate reductase alpha subunit | 0.0647 | 0.4885 | 0.4885 |
Trypanosoma cruzi | ribonucleoside-diphosphate reductase large chain, putative | 0.0184 | 0.1285 | 0.2568 |
Toxoplasma gondii | eukaryotic aspartyl protease superfamily protein | 0.0034 | 0.012 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0272 | 0.0557 |
Plasmodium falciparum | plasmepsin I | 0.0034 | 0.012 | 0.0146 |
Trichomonas vaginalis | conserved hypothetical protein | 0.005 | 0.0246 | 0.0457 |
Schistosoma mansoni | hypothetical protein | 0.0053 | 0.0272 | 0.0272 |
Onchocerca volvulus | 0.0034 | 0.012 | 0.384 | |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Echinococcus granulosus | neuroendocrine convertase 2 | 0.005 | 0.0246 | 0.0487 |
Toxoplasma gondii | subtilisin SUB5 | 0.005 | 0.0246 | 0.038 |
Schistosoma mansoni | subfamily S8B unassigned peptidase (S08 family) | 0.005 | 0.0246 | 0.0246 |
Echinococcus multilocularis | proprotein convertase subtilisin:kexin type 5 | 0.005 | 0.0246 | 0.0487 |
Plasmodium falciparum | plasmepsin VI | 0.0034 | 0.012 | 0.0146 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0059 | 0.012 |
Plasmodium falciparum | plasmepsin X | 0.0034 | 0.012 | 0.0146 |
Loa Loa (eye worm) | ribonucleotide reductase M2 B | 0.0138 | 0.0931 | 0.1906 |
Loa Loa (eye worm) | endoprotease bli-4 | 0.005 | 0.0246 | 0.0503 |
Plasmodium falciparum | plasmepsin V | 0.0034 | 0.012 | 0.0146 |
Plasmodium vivax | subtilisin-like protease 2, putative | 0.005 | 0.0246 | 0.038 |
Echinococcus multilocularis | eukaryotic initiation factor 4A III | 0.0024 | 0.0042 | 0.0082 |
Plasmodium falciparum | plasmepsin IV | 0.0034 | 0.012 | 0.0146 |
Mycobacterium tuberculosis | Probable membrane-anchored mycosin MycP4 (serine protease) (subtilisin-like protease) (subtilase-like) (mycosin-4) | 0.005 | 0.0246 | 0.0457 |
Plasmodium vivax | aspartyl protease, putative | 0.0034 | 0.012 | 0.0146 |
Trypanosoma brucei | ribonucleoside-diphosphate reductase small chain, putative | 0.0138 | 0.0931 | 0.1837 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Plasmodium vivax | subtilisin-like serine protease, putative | 0.005 | 0.0246 | 0.038 |
Plasmodium falciparum | plasmepsin IX | 0.0034 | 0.012 | 0.0146 |
Schistosoma mansoni | ribonucleoside-diphosphate reductase small chain | 0.0138 | 0.0931 | 0.0931 |
Trypanosoma cruzi | subtilisin peptidase | 0.005 | 0.0246 | 0.0422 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0034 | 0.012 | 0.012 |
Plasmodium falciparum | subtilisin-like protease 1 | 0.0716 | 0.5422 | 1 |
Schistosoma mansoni | subfamily M12B unassigned peptidase (M12 family) | 0.0044 | 0.0202 | 0.0202 |
Brugia malayi | ADAM-TS Spacer 1 family protein | 0.0026 | 0.0059 | 0.012 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0034 | 0.012 | 0.012 |
Plasmodium vivax | ribonucleoside-diphosphate reductase small chain, putative | 0.0138 | 0.0931 | 0.1654 |
Treponema pallidum | ribonucleotide-diphosphate reductase subunit beta | 0.0138 | 0.0931 | 0.1837 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Plasmodium falciparum | subtilisin-like protease 3 | 0.005 | 0.0246 | 0.038 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.005 | 0.0246 | 0.0457 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Dose (functional) | = 100 mg kg-1 | In vivo for the optimal dose for activity against P388 leukemia per injection | ChEMBL. | 3397990 |
IC50 (functional) | 0 M | In vitro for its inhibitory activity against murine L1210 leukemia; Inactive | ChEMBL. | 3397990 |
Net log cell kill (ADMET) | = 6 | Net log value of the compound for P388 leukemia cell kill in mice was determined | ChEMBL. | 3397990 |
T/C (functional) | = 220 % | Percentage ratio of treated animals to cured animals against P388 leukemia (day 30 surv) | ChEMBL. | 3397990 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.