Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | glutathione synthetase | 0.0498 | 0.3247 | 0.3247 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.033 | 0.2091 | 0.2088 |
Schistosoma mansoni | intermediate filament proteins | 0.0116 | 0.0628 | 0.0628 |
Loa Loa (eye worm) | polyprenyl synthetase | 0.1482 | 1 | 1 |
Giardia lamblia | Farnesyl diphosphate synthase | 0.1482 | 1 | 1 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0027 | 0.0011 | 0.0011 |
Trichomonas vaginalis | esterase, putative | 0.0108 | 0.0572 | 0.0493 |
Loa Loa (eye worm) | intermediate filament protein | 0.0116 | 0.0628 | 0.0624 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.02 | 0.0196 |
Plasmodium vivax | hypothetical protein, conserved | 0.0108 | 0.0572 | 0.0568 |
Brugia malayi | MH2 domain containing protein | 0.0389 | 0.2499 | 0.2496 |
Brugia malayi | MH1 domain containing protein | 0.0027 | 0.0011 | 0.0007 |
Onchocerca volvulus | 0.0116 | 0.0628 | 1 | |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0112 | 0.0596 | 0.0596 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.021 | 0.1273 | 0.1269 |
Plasmodium vivax | vivapain-2 | 0.0037 | 0.0083 | 0.0079 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 0.026 | 0.0256 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0037 | 0.0083 | 0.0083 |
Leishmania major | polyprenyl synthase, putative | 0.0754 | 0.5002 | 0.5 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0051 | 0.0178 | 0.0377 |
Trypanosoma brucei | solanesyl-diphosphate synthase, putative | 0.0667 | 0.4405 | 0.4403 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0037 | 0.0083 | 0.0083 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0104 | 0.0544 | 0.0541 |
Trypanosoma brucei | farnesyl pyrophosphate synthase | 0.1482 | 1 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0037 | 0.0083 | 0.0079 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0112 | 0.0596 | 0.0243 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.0795 | 0.0791 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0116 | 0.0628 | 0.0624 |
Mycobacterium ulcerans | hypothetical protein | 0.0174 | 0.1021 | 0.0684 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0108 | 0.0572 | 0.0401 |
Onchocerca volvulus | 0.0108 | 0.0572 | 0.897 | |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0129 | 0.0711 | 0.0708 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0052 | 0.0186 | 0.0186 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.0454 | 0.0454 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0052 | 0.0186 | 0.0055 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0046 | 0.0147 | 0.0143 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0108 | 0.0572 | 0.0568 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0052 | 0.0186 | 0.0182 |
Mycobacterium ulcerans | geranylgeranyl pyrophosphate synthase | 0.1482 | 1 | 1 |
Schistosoma mansoni | lamin | 0.0116 | 0.0628 | 0.0628 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0052 | 0.0186 | 0.0104 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.0795 | 0.0791 |
Toxoplasma gondii | cathepsin CPL | 0.0037 | 0.0083 | 0.0079 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.0795 | 0.0791 |
Mycobacterium tuberculosis | Conserved protein | 0.0108 | 0.0572 | 0.0401 |
Echinococcus granulosus | lamin dm0 | 0.0116 | 0.0628 | 0.0628 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 0.026 | 0.0256 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0056 | 0.0215 | 0.0215 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.033 | 0.2091 | 0.2088 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0112 | 0.0596 | 0.0243 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0286 | 0.0286 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0111 | 0.0588 | 0.0585 |
Schistosoma mansoni | smad1 5 8 and | 0.0027 | 0.0011 | 0.0011 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0108 | 0.0572 | 0.0493 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0037 | 0.0083 | 0.0083 |
Echinococcus multilocularis | cysteine protease | 0.0037 | 0.0083 | 0.0083 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0056 | 0.0217 | 0.0213 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0062 | 0.0257 | 0.0253 |
Leishmania major | cathepsin L-like protease | 0.0037 | 0.0083 | 0.0079 |
Leishmania major | cathepsin L-like protease | 0.0037 | 0.0083 | 0.0079 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.008 | 0.008 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.0795 | 0.0791 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0052 | 0.0186 | 0.0182 |
Loa Loa (eye worm) | hypothetical protein | 0.0144 | 0.0816 | 0.0813 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.1412 | 0.9516 | 0.9516 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0361 | 0.0357 |
Plasmodium vivax | octaprenyl pyrophosphate synthase, putative | 0.0667 | 0.4405 | 0.4403 |
Loa Loa (eye worm) | acetyltransferase | 0.0166 | 0.0968 | 0.0965 |
Trypanosoma cruzi | farnesyl pyrophosphate synthase, putative | 0.1482 | 1 | 1 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0108 | 0.0572 | 0.0493 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0037 | 0.0083 | 0.0079 |
Treponema pallidum | octaprenyl-diphosphate synthase | 0.0754 | 0.5002 | 1 |
Echinococcus multilocularis | geranylgeranyl pyrophosphate synthase | 0.0754 | 0.5002 | 0.5002 |
Echinococcus multilocularis | lamin dm0 | 0.0116 | 0.0628 | 0.0628 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0037 | 0.0083 | 0.0079 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0067 | 0.0286 | 0.0282 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.02 | 0.0196 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.026 | 0.026 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0027 | 0.0013 | 0.0009 |
Brugia malayi | Polyprenyl synthetase family protein | 0.0667 | 0.4405 | 0.4403 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0027 | 0.0011 | 0.0011 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0141 | 0.0795 | 0.0791 |
Brugia malayi | Bromodomain containing protein | 0.0046 | 0.0147 | 0.0143 |
Trypanosoma cruzi | polyprenyl synthase, putative | 0.0754 | 0.5002 | 0.5 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0144 | 0.0816 | 0.0813 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0067 | 0.0286 | 0.0286 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0052 | 0.0186 | 0.0104 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0108 | 0.0572 | 0.0572 |
Leishmania major | cathepsin L-like protease | 0.0037 | 0.0083 | 0.0079 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0141 | 0.0795 | 0.0791 |
Echinococcus multilocularis | cysteine protease | 0.0037 | 0.0083 | 0.0083 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.0454 | 0.0454 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0078 | 0.0361 | 0.0361 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0286 | 0.0282 |
Schistosoma mansoni | zinc finger protein | 0.0026 | 0.0005 | 0.0005 |
Mycobacterium ulcerans | hypothetical protein | 0.0108 | 0.0572 | 0.0218 |
Echinococcus granulosus | GPCR family 2 | 0.0067 | 0.0286 | 0.0286 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.018 | 0.0176 |
Echinococcus granulosus | cathepsin l1 | 0.0037 | 0.0083 | 0.0083 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0046 | 0.0147 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0572 | 0.0568 |
Schistosoma mansoni | smad1 5 8 and | 0.0027 | 0.0011 | 0.0011 |
Schistosoma mansoni | farnesyl pyrophosphate synthase | 0.1482 | 1 | 1 |
Trypanosoma cruzi | solanesyl-diphosphate synthase, putative | 0.0667 | 0.4405 | 0.4403 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0628 | 0.0624 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0108 | 0.0572 | 0.0493 |
Echinococcus granulosus | intermediate filament protein | 0.0116 | 0.0628 | 0.0628 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0078 | 0.0361 | 0.0794 |
Brugia malayi | beta-lactamase family protein | 0.0108 | 0.0572 | 0.0568 |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0083 | 0.0079 |
Trichomonas vaginalis | geranylgeranyl pyrophosphate synthase, putative | 0.1482 | 1 | 1 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0108 | 0.0572 | 0.0568 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0037 | 0.0083 | 0.0083 |
Leishmania major | cathepsin L-like protease | 0.0141 | 0.0795 | 0.0791 |
Schistosoma mansoni | geranylgeranyl pyrophosphate synthase | 0.0754 | 0.5002 | 0.5002 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.026 | 0.026 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0174 | 0.1021 | 0.0858 |
Schistosoma mansoni | microtubule-associated protein tau | 0.1412 | 0.9516 | 0.9516 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0037 | 0.0083 | 0.0079 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0091 | 0.0454 | 0.045 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0141 | 0.0795 | 0.0791 |
Leishmania major | cathepsin L-like protease | 0.0037 | 0.0083 | 0.0079 |
Echinococcus granulosus | Smad4 | 0.0027 | 0.0011 | 0.0011 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.007 | 0.0309 | 0.0309 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.004 | 0.0101 | 0.0101 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0044 | 0.0132 | 0.0128 |
Mycobacterium ulcerans | polyprenyl synthetase IdsB | 0.0498 | 0.3247 | 0.2994 |
Echinococcus granulosus | smad | 0.0027 | 0.0011 | 0.0011 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.0361 | 0.0357 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0165 | 0.0161 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.033 | 0.2091 | 0.2088 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0037 | 0.0083 | 0.0079 |
Schistosoma mansoni | lamin | 0.0116 | 0.0628 | 0.0628 |
Schistosoma mansoni | trans-prenyltransferase | 0.0667 | 0.4405 | 0.4405 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.0795 | 0.0791 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0112 | 0.0596 | 0.0592 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.007 | 0.0309 | 0.0309 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0156 | 0.09 | 0.0896 |
Trypanosoma cruzi | solanesyl-diphosphate synthase | 0.0667 | 0.4405 | 0.4403 |
Loa Loa (eye worm) | cysteine protease | 0.0037 | 0.0083 | 0.0079 |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0083 | 0.0079 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0027 | 0.0011 | 0.0011 |
Leishmania major | farnesyl pyrophosphate synthase | 0.1482 | 1 | 1 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0112 | 0.0596 | 0.0596 |
Schistosoma mansoni | smad | 0.0027 | 0.0011 | 0.0011 |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0083 | 0.0079 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0078 | 0.0361 | 0.0357 |
Schistosoma mansoni | smad1 5 8 and | 0.0027 | 0.0011 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0572 | 0.0568 |
Leishmania major | cathepsin L-like protease | 0.0037 | 0.0083 | 0.0079 |
Entamoeba histolytica | geranylgeranyl pyrophosphate synthetase, putative | 0.0667 | 0.4405 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0027 | 0.0011 | 0.0007 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0067 | 0.0286 | 0.0282 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.0454 | 0.0454 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.0454 | 0.0454 |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0083 | 0.0079 |
Trypanosoma cruzi | polyprenyl synthase, putative | 0.0754 | 0.5002 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0141 | 0.0795 | 0.0791 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.026 | 0.026 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0051 | 0.0177 | 0.0173 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.012 | 0.0116 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0091 | 0.0454 | 0.045 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0067 | 0.0286 | 0.0282 |
Trypanosoma brucei | protein kinase, putative | 0.0052 | 0.0186 | 0.0182 |
Loa Loa (eye worm) | polyprenyl synthetase | 0.0667 | 0.4405 | 0.4403 |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0083 | 0.0079 |
Echinococcus multilocularis | farnesyl pyrophosphate synthase | 0.1482 | 1 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0027 | 0.0011 | 0.0007 |
Brugia malayi | beta-lactamase family protein | 0.0108 | 0.0572 | 0.0568 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0108 | 0.0572 | 0.0568 |
Schistosoma mansoni | Smad4 | 0.0027 | 0.0011 | 0.0011 |
Toxoplasma gondii | hypothetical protein | 0.0053 | 0.0194 | 0.019 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0052 | 0.0186 | 0.0186 |
Plasmodium falciparum | geranylgeranyl pyrophosphate synthase, putative | 0.1482 | 1 | 1 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0078 | 0.0361 | 0.0357 |
Entamoeba histolytica | cysteine protease, putative | 0.0037 | 0.0083 | 0.0007 |
Brugia malayi | Smad1 | 0.0027 | 0.0011 | 0.0007 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0108 | 0.0572 | 0.0401 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0037 | 0.0083 | 0.0007 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0051 | 0.0177 | 0.0095 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0112 | 0.0596 | 0.0425 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0052 | 0.0186 | 0.0182 |
Echinococcus granulosus | lamin | 0.0116 | 0.0628 | 0.0628 |
Echinococcus granulosus | zinc finger protein | 0.0026 | 0.0005 | 0.0005 |
Mycobacterium leprae | Probable lipase LipE | 0.0108 | 0.0572 | 0.1273 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.008 | 0.008 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.0795 | 0.0791 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0108 | 0.0572 | 0.0568 |
Echinococcus multilocularis | Smad4 | 0.0027 | 0.0011 | 0.0011 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0062 | 0.0257 | 0.0253 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0052 | 0.0186 | 0.0182 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0037 | 0.0083 | 0.0083 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0044 | 0.0132 | 0.012 |
Echinococcus multilocularis | prenyl (decaprenyl) diphosphate synthase | 0.0498 | 0.3247 | 0.3247 |
Mycobacterium tuberculosis | Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) | 0.1482 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0037 | 0.0083 | 0.0083 |
Mycobacterium ulcerans | lipase LipD | 0.0108 | 0.0572 | 0.0218 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.0795 | 0.0791 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0572 | 0.0568 |
Brugia malayi | geranylgeranyl pyrophosphate synthetase | 0.0754 | 0.5002 | 0.5 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0051 | 0.0177 | 0.0173 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 0.026 | 0.0256 |
Brugia malayi | Probable ClpP-like protease | 0.0078 | 0.0361 | 0.0357 |
Wolbachia endosymbiont of Brugia malayi | geranylgeranyl pyrophosphate synthase | 0.0498 | 0.3247 | 0.7136 |
Mycobacterium leprae | PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) | 0.0667 | 0.4405 | 1 |
Echinococcus granulosus | farnesyl pyrophosphate synthase | 0.1482 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.0795 | 0.0791 |
Plasmodium vivax | vivapain-2 | 0.0037 | 0.0083 | 0.0079 |
Brugia malayi | Bromodomain containing protein | 0.0087 | 0.0424 | 0.042 |
Mycobacterium tuberculosis | Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate | 0.0498 | 0.3247 | 0.3125 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0052 | 0.0186 | 0.0104 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.008 | 0.008 |
Brugia malayi | TAR-binding protein | 0.0063 | 0.026 | 0.0256 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.0613 | 0.061 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0108 | 0.0572 | 0.0218 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0037 | 0.0083 | 0.0083 |
Brugia malayi | intermediate filament protein | 0.0116 | 0.0628 | 0.0624 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0037 | 0.0083 | 0.0083 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0108 | 0.0572 | 0.0572 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0108 | 0.0572 | 0.0572 |
Onchocerca volvulus | 0.0108 | 0.0572 | 0.897 | |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0108 | 0.0572 | 0.0572 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0112 | 0.0596 | 0.0596 |
Mycobacterium tuberculosis | Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) | 0.0498 | 0.3247 | 0.3125 |
Onchocerca volvulus | 0.0116 | 0.0628 | 1 | |
Trichomonas vaginalis | CMGC family protein kinase | 0.0052 | 0.0186 | 0.0104 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0051 | 0.0178 | 0.0178 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0078 | 0.0361 | 0.0361 |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 0.026 | 0.0256 |
Mycobacterium tuberculosis | Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) | 0.0498 | 0.3247 | 0.3125 |
Echinococcus granulosus | decaprenyl diphosphate synthase subunit 1 | 0.0667 | 0.4405 | 0.4405 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0027 | 0.0011 | 0.0007 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0051 | 0.0178 | 0.0178 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.0454 | 0.0454 |
Schistosoma mansoni | bromodomain containing protein | 0.0074 | 0.0336 | 0.0336 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 0.026 | 0.026 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0067 | 0.0286 | 0.0286 |
Echinococcus multilocularis | zinc finger protein | 0.0026 | 0.0005 | 0.0005 |
Chlamydia trachomatis | geranylgeranyl pyrophosphate synthase | 0.0498 | 0.3247 | 1 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0156 | 0.09 | 0.0896 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0052 | 0.0186 | 0.0186 |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 0.026 | 0.026 |
Loa Loa (eye worm) | fibroinase | 0.0037 | 0.0083 | 0.0079 |
Brugia malayi | hypothetical protein | 0.0036 | 0.008 | 0.0076 |
Toxoplasma gondii | polyprenyl synthetase superfamily protein | 0.0667 | 0.4405 | 0.4403 |
Echinococcus multilocularis | lamin | 0.0116 | 0.0628 | 0.0628 |
Plasmodium falciparum | octaprenyl pyrophosphate synthase | 0.0667 | 0.4405 | 0.4403 |
Loa Loa (eye worm) | beta-lactamase | 0.0108 | 0.0572 | 0.0568 |
Trichomonas vaginalis | geranylgeranyl diphosphate synthase, putative | 0.1482 | 1 | 1 |
Brugia malayi | beta-lactamase | 0.0108 | 0.0572 | 0.0568 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0051 | 0.0177 | 0.0173 |
Brugia malayi | MH1 domain containing protein | 0.0027 | 0.0011 | 0.0007 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.026 | 0.026 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0108 | 0.0572 | 0.0568 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0046 | 0.0147 | 0.0143 |
Mycobacterium ulcerans | polyprenyl diphosphate synthetase, GrcC1 | 0.0667 | 0.4405 | 0.4196 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0067 | 0.0286 | 0.0286 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0027 | 0.0011 | 0.0011 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0108 | 0.0572 | 0.0218 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0156 | 0.09 | 0.0896 |
Leishmania major | mitochondrial DNA polymerase beta | 0.033 | 0.2091 | 0.2088 |
Schistosoma mansoni | hypothetical protein | 0.0144 | 0.0816 | 0.0816 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.0361 | 0.0699 |
Echinococcus granulosus | microtubule associated protein 2 | 0.1412 | 0.9516 | 0.9516 |
Echinococcus granulosus | geranylgeranyl pyrophosphate synthase | 0.0754 | 0.5002 | 0.5002 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0389 | 0.2499 | 0.2496 |
Echinococcus multilocularis | smad | 0.0027 | 0.0011 | 0.0011 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.0795 | 0.0791 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0112 | 0.0596 | 0.0592 |
Mycobacterium ulcerans | beta-lactamase | 0.0108 | 0.0572 | 0.0218 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0108 | 0.0572 | 0.0493 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0078 | 0.0361 | 0.0357 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0056 | 0.0215 | 0.0215 |
Brugia malayi | MH2 domain containing protein | 0.0027 | 0.0011 | 0.0007 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0067 | 0.0286 | 0.0286 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0691 | 0.4573 | 0.4475 |
Toxoplasma gondii | polyprenyl synthetase superfamily protein | 0.1482 | 1 | 1 |
Echinococcus granulosus | prenyl decaprenyl diphosphate synthase | 0.0498 | 0.3247 | 0.3247 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0572 | 0.0568 |
Plasmodium vivax | geranylgeranyl pyrophosphate synthase | 0.1482 | 1 | 1 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0108 | 0.0572 | 0.0401 |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0083 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0215 | 0.0211 |
Trypanosoma cruzi | solanesyl-diphosphate synthase, putative | 0.0667 | 0.4405 | 0.4403 |
Leishmania major | hypothetical protein, conserved | 0.0108 | 0.0572 | 0.0568 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.0795 | 0.0791 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0027 | 0.0013 | 0.0009 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0116 | 0.0628 | 0.0624 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0108 | 0.0572 | 0.0401 |
Wolbachia endosymbiont of Brugia malayi | geranylgeranyl pyrophosphate synthase | 0.0667 | 0.4405 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0108 | 0.0572 | 0.0401 |
Mycobacterium leprae | conserved hypothetical protein | 0.0108 | 0.0572 | 0.1273 |
Entamoeba histolytica | bifunctional short chain isoprenyl diphosphate synthase, putative | 0.0498 | 0.3247 | 0.7323 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.026 | 0.026 |
Echinococcus multilocularis | musashi | 0.0116 | 0.0628 | 0.0628 |
Brugia malayi | PHD-finger family protein | 0.0031 | 0.0045 | 0.0041 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0166 | 0.0968 | 0.0968 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0037 | 0.0083 | 0.0007 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0108 | 0.0572 | 0.0401 |
Loa Loa (eye worm) | Smad1 | 0.0027 | 0.0011 | 0.0007 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0052 | 0.0186 | 0.0186 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.0795 | 0.0791 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0572 | 0.0568 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0051 | 0.0177 | 0.0095 |
Mycobacterium tuberculosis | Conserved protein | 0.0108 | 0.0572 | 0.0401 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0159 | 0.0919 | 0.0919 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0108 | 0.0572 | 0.0401 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.021 | 0.1273 | 0.1269 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0052 | 0.0186 | 0.0182 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0052 | 0.0186 | 0.0182 |
Brugia malayi | RNA binding protein | 0.0063 | 0.026 | 0.0256 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0027 | 0.0011 | 0.0011 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0286 | 0.0286 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0108 | 0.0572 | 0.0401 |
Entamoeba histolytica | geranylgeranyl pyrophosphate synthase, putative | 0.0667 | 0.4405 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.0037 | 0.0083 | 0.0079 |
Mycobacterium ulcerans | geranylgeranyl pyrophosphate synthase | 0.1482 | 1 | 1 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0078 | 0.0361 | 0.0361 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0389 | 0.2499 | 0.2496 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0166 | 0.0968 | 0.0968 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.0454 | 0.0454 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0052 | 0.0186 | 0.0182 |
Leishmania major | cathepsin L-like protease | 0.0141 | 0.0795 | 0.0791 |
Mycobacterium tuberculosis | Probable polyprenyl-diphosphate synthase GrcC1 (polyprenyl pyrophosphate synthetase) | 0.0169 | 0.0988 | 0.0824 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.008 | 0.008 |
Trypanosoma cruzi | farnesyl pyrophosphate synthase | 0.1482 | 1 | 1 |
Echinococcus multilocularis | GPCR, family 2 | 0.0067 | 0.0286 | 0.0286 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0052 | 0.0186 | 0.0182 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0051 | 0.0177 | 0.0177 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0141 | 0.0795 | 0.0791 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0037 | 0.0083 | 0.0079 |
Brugia malayi | MAP kinase sur-1 | 0.0052 | 0.0186 | 0.0182 |
Toxoplasma gondii | hypothetical protein | 0.0027 | 0.0013 | 0.0009 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0166 | 0.0968 | 0.0965 |
Loa Loa (eye worm) | geranylgeranyl pyrophosphate synthetase | 0.0754 | 0.5002 | 0.5 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0052 | 0.0186 | 0.0182 |
Leishmania major | solanesyl-diphosphate synthase, putative | 0.0667 | 0.4405 | 0.4403 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0572 | 0.0568 |
Echinococcus multilocularis | decaprenyl diphosphate synthase subunit 1 | 0.0667 | 0.4405 | 0.4405 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0364 | 0.0361 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.0454 | 0.0454 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0037 | 0.0083 | 0.0079 |
Toxoplasma gondii | ABC1 family protein | 0.0108 | 0.0572 | 0.0568 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0108 | 0.0572 | 0.0493 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.004 | 0.0101 | 0.0101 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0286 | 0.0286 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0046 | 0.0147 | 0.0143 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0083 | 0.0079 |
Trichomonas vaginalis | geranylgeranyl pyrophosphate synthase, putative | 0.1482 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.021 | 0.1273 | 0.1269 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0037 | 0.0083 | 0.0079 |
Onchocerca volvulus | 0.0108 | 0.0572 | 0.897 | |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0286 | 0.0286 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.021 | 0.1273 | 0.1269 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0052 | 0.0186 | 0.0186 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.