Detailed information for compound 561337

Basic information

Technical information
  • TDR Targets ID: 561337
  • Name: 5-[2-[(2-iodoacetyl)amino]ethylamino]naphthal ene-1-sulfonic acid
  • MW: 434.249 | Formula: C14H15IN2O4S
  • H donors: 3 H acceptors: 4 LogP: 1.9 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: ICC(=O)NCCNc1cccc2c1cccc2S(=O)(=O)O
  • InChi: 1S/C14H15IN2O4S/c15-9-14(18)17-8-7-16-12-5-1-4-11-10(12)3-2-6-13(11)22(19,20)21/h1-6,16H,7-9H2,(H,17,18)(H,19,20,21)
  • InChiKey: ZMERMCRYYFRELX-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 5-[2-[(2-iodo-1-oxoethyl)amino]ethylamino]-1-naphthalenesulfonic acid
  • 5-[2-(2-iodoethanoylamino)ethylamino]naphthalene-1-sulfonic acid
  • 1,5-I-AEDANS
  • 36930-63-9
  • to_000065
  • 5-(2-(2-Iodoacetamido)ethylamino)-1-naphthalenesulphonic acid
  • EINECS 253-277-7
  • N-(Iodoacetylaminoethyl)-5-naphthylamine-1-sulfonic acid
  • NSC 328384
  • N-(Iodoacetaminoethyl)-1-naphthylamine-5-sulfonate, N-(Iodoacetyl-aminoethyl)-5-N'-naphthylamin-1-sulfonic acid (1,5-IAEDANS)
  • N-(Iodoacetaminoethyl)-1-naphthylamine-5-sulfonate
  • SGCUT00111
  • NSC328384
  • 5-((2-[(Iodoacetyl)amino]ethyl)amino)-1-naphthalenesulfonic acid
  • 5-(2-(2-Iodoacetamido)ethylamino)-1-naphthalenesulfonic acid
  • 5-[2-(Iodoacetamido)ethylamino]naphthalene-1-sulfonic acid
  • 57672_FLUKA
  • Hudson-Weber-Reagent
  • N-(Iodoacetaminoethyl)-1-naphthylamine-5-sulfonic acid
  • N-Iodoacetyl-N'-(5-sulfo-1-naphthyl)ethylenediamine

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0925
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0038 0.0026 0.3907
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0015 0.0633
Loa Loa (eye worm) hypothetical protein 0.0073 0.0063 0.0063
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0027 0.0015 0.0015
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0124 0.0117 0.0117
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0027 0.0015 0.2201
Loa Loa (eye worm) hypothetical protein 0.0371 0.0375 0.0375
Echinococcus granulosus calpain A 0.0038 0.0026 0.0026
Toxoplasma gondii aspartyl protease ASP1 0.0129 0.0122 1
Schistosoma mansoni smad1 5 8 and 0.0016 0.0003 0.0003
Echinococcus granulosus cpg binding protein 0.0034 0.0022 0.0022
Schistosoma mansoni memapsin-2 (A01 family) 0.2565 0.2679 0.2679
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0015 0.0633
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0006 0.0006
Trypanosoma cruzi ISWI complex protein 0.0031 0.0019 0.2894
Brugia malayi CXXC zinc finger family protein 0.0029 0.0016 0.0016
Onchocerca volvulus 0.0109 0.0101 0.2682
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0027 0.0015 0.0633
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0015 0.0633
Leishmania major hypothetical protein, conserved 0.0031 0.0019 0.2596
Schistosoma mansoni zinc finger protein 0.0031 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0213 0.021 0.021
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0129 0.0122 0.0122
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0109 0.0101 0.0101
Loa Loa (eye worm) DIX domain-containing protein 0.0018 0.0005 0.0005
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0003 0.0003
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0124 0.0117 0.0117
Loa Loa (eye worm) RNA binding protein 0.013 0.0123 0.0123
Echinococcus granulosus regulator of G protein signaling 7 0.0018 0.0005 0.0005
Trypanosoma brucei calpain-like protein, putative 0.0038 0.0026 0.3897
Echinococcus multilocularis cpg binding protein 0.0034 0.0022 0.0022
Toxoplasma gondii aspartyl protease ASP3 0.0109 0.0101 0.8242
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0925
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0925
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0003 0.0003
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0016 0.0016
Schistosoma mansoni DNA polymerase eta 0.0019 0.0006 0.0006
Loa Loa (eye worm) transcription factor SMAD2 0.0236 0.0234 0.0234
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0011 0.0682
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0038 0.0026 0.3907
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.0005
Brugia malayi hypothetical protein 0.005 0.0038 0.0038
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0015 0.0633
Onchocerca volvulus 0.003 0.0018 0.0479
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0063 0.2716
Mycobacterium tuberculosis Probable hydrolase 0.0073 0.0063 0.1275
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0204 0.0201 0.0201
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0083 0.0073 0.0073
Schistosoma mansoni hypothetical protein 0.0407 0.0414 0.0414
Mycobacterium ulcerans esterase/lipase LipP 0.0073 0.0063 1
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0038 0.0026 0.3907
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0027 0.0015 0.2188
Echinococcus granulosus Smad4 0.0016 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0073 0.0063 0.0063
Brugia malayi calpain 5 0.0038 0.0026 0.0026
Mycobacterium tuberculosis Probable lipase LipE 0.0073 0.0063 0.1275
Schistosoma mansoni apoferritin-2 0.0017 0.0005 0.0005
Brugia malayi MH1 domain containing protein 0.0016 0.0003 0.0003
Schistosoma mansoni tar DNA-binding protein 0.013 0.0123 0.0123
Brugia malayi aspartic protease BmAsp-1, identical 0.0109 0.0101 0.0101
Echinococcus multilocularis GPCR, family 2 0.0095 0.0086 0.0086
Plasmodium vivax aspartyl protease, putative 0.0109 0.0101 0.8242
Echinococcus granulosus histone acetyltransferase MYST2 0.0054 0.0043 0.0043
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0038 0.0026 0.3651
Loa Loa (eye worm) hypothetical protein 0.4054 0.424 0.424
Echinococcus granulosus calpain 0.0038 0.0026 0.0026
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0074 0.0064 0.0064
Schistosoma mansoni hypothetical protein 0.0042 0.0031 0.0031
Schistosoma mansoni Mername-AA248 (C02 family) 0.0038 0.0026 0.0026
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0109 0.0101 0.0101
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0468 0.0478 1
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0003 0.0003
Echinococcus granulosus zinc finger protein 0.0042 0.003 0.003
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0371 0.0375 1
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.002 0.0007 0.0087
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0038 0.0026 0.3907
Plasmodium falciparum plasmepsin V 0.0109 0.0101 0.8242
Trichomonas vaginalis ferritin, putative 0.0017 0.0005 0.02
Brugia malayi DIX domain containing protein 0.0018 0.0005 0.0005
Schistosoma mansoni cpg binding protein 0.0034 0.0022 0.0022
Echinococcus granulosus fetal alzheimer antigen falz 0.0048 0.0037 0.0037
Schistosoma mansoni hypothetical protein 0.0034 0.0023 0.0023
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0011 0.0171
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0003 0.0003
Echinococcus granulosus GPCR family 2 0.0095 0.0086 0.0086
Loa Loa (eye worm) calpain family protein 1 0.009 0.008 0.008
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0018 0.0018
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0015 0.0633
Echinococcus granulosus expressed protein 0.0017 0.0005 0.0005
Echinococcus multilocularis Pleckstrin G protein, interacting region 0.0018 0.0005 0.0005
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0109 0.0101 0.0101
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0011 0.1599
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0011 0.0682
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0015 0.0633
Brugia malayi TAR-binding protein 0.013 0.0123 0.0123
Trypanosoma cruzi PAB1-binding protein , putative 0.0077 0.0067 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0925
Loa Loa (eye worm) hypothetical protein 0.0109 0.0101 0.0101
Echinococcus granulosus tar DNA binding protein 0.013 0.0123 0.0123
Entamoeba histolytica hypothetical protein 0.0023 0.0011 0.4129
Schistosoma mansoni hypothetical protein 0.0095 0.0086 0.0086
Echinococcus multilocularis dna polymerase eta 0.0019 0.0006 0.0006
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0011 1
Brugia malayi Eukaryotic aspartyl protease family protein 0.0109 0.0101 0.0101
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0074 0.0064 0.0064
Loa Loa (eye worm) hypothetical protein 0.0146 0.0139 0.0139
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0038 0.0026 0.3907
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0038 0.0026 0.3897
Brugia malayi regulator of G-protein signaling egl-10 0.0018 0.0005 0.0005
Schistosoma mansoni cpg binding protein 0.0034 0.0022 0.0022
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0095 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0129 0.0122 0.0122
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.0023 0.0023
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0003 0.0003
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0063 0.2716
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0011 0.1049
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0073 0.0063 0.0063
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0036 0.0036
Schistosoma mansoni zinc finger protein 0.0042 0.003 0.003
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0109 0.0101 0.8242
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0003 0.0003
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0006 0.0006
Loa Loa (eye worm) latrophilin receptor protein 2 0.0095 0.0086 0.0086
Leishmania major hypothetical protein, conserved 0.0077 0.0067 1
Trichomonas vaginalis esterase, putative 0.0073 0.0063 0.2716
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0011 0.1049
Echinococcus granulosus Pleckstrin G protein interacting region 0.0018 0.0005 0.0005
Echinococcus multilocularis hypothetical protein 0.0038 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0065 0.0055 0.0055
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0029 0.0017 0.0017
Schistosoma mansoni cathepsin D (A01 family) 0.018 0.0175 0.0175
Echinococcus granulosus beta LACTamase domain containing family member 0.0073 0.0063 0.0063
Mycobacterium ulcerans lipase LipD 0.0073 0.0063 1
Trichomonas vaginalis set domain proteins, putative 0.0235 0.0233 1
Onchocerca volvulus 0.0109 0.0101 0.2682
Schistosoma mansoni z-protein (S1r protein) 0.0018 0.0005 0.0005
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0015 0.0633
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.024 0.0239 0.0239
Plasmodium falciparum plasmepsin IV 0.0129 0.0122 1
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0015 0.0633
Schistosoma mansoni smad1 5 8 and 0.0016 0.0003 0.0003
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0018 0.0005 0.0005
Echinococcus multilocularis geminin 0.0511 0.0523 0.0523
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0055 0.0055
Schistosoma mansoni ferritin light chain 0.0017 0.0005 0.0005
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0047 0.0036 0.0964
Schistosoma mansoni tar DNA-binding protein 0.013 0.0123 0.0123
Schistosoma mansoni ferritin 0.0017 0.0005 0.0005
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0011 0.0682
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0129 0.0122 1
Loa Loa (eye worm) hypothetical protein 0.0079 0.0069 0.0069
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0206 0.0203 0.0203
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0027 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0007 0.0294
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0027 0.0015 0.0633
Brugia malayi calpain 7 0.0038 0.0026 0.0026
Leishmania major DNA polymerase kappa, putative 0.0019 0.0006 0.056
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0925
Trypanosoma brucei calpain-like protein, putative 0.0038 0.0026 0.3897
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0083 0.0073 0.0073
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0073 0.0063 0.1275
Loa Loa (eye worm) hypothetical protein 0.0233 0.0231 0.0231
Toxoplasma gondii hypothetical protein 0.0018 0.0005 0.0235
Echinococcus granulosus dna polymerase kappa 0.0019 0.0006 0.0006
Toxoplasma gondii LsmAD domain-containing protein 0.0077 0.0067 0.5409
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0027 0.0015 0.0633
Brugia malayi Pre-SET motif family protein 0.003 0.0018 0.0018
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0134 0.0127 0.0127
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0003 0.0003
Echinococcus granulosus bifunctional protein NCOAT 0.9542 1 1
Echinococcus granulosus smad 0.0016 0.0003 0.0003
Echinococcus granulosus microtubule associated protein 2 0.0738 0.076 0.076
Echinococcus multilocularis polycomb protein SCMH1 0.0047 0.0036 0.0036
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0015 0.0633
Loa Loa (eye worm) MH2 domain-containing protein 0.0236 0.0234 0.0234
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0128 0.012 0.012
Brugia malayi Bromodomain containing protein 0.0079 0.0069 0.0069
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0003 0.0003
Plasmodium falciparum plasmepsin II 0.0129 0.0122 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.013 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.0128 0.012 0.012
Mycobacterium tuberculosis Conserved protein 0.0073 0.0063 0.1275
Echinococcus granulosus dnaJ subfamily B 0.0407 0.0414 0.0414
Echinococcus multilocularis calpain family protein 1, d 0.009 0.008 0.008
Brugia malayi MH2 domain containing protein 0.0016 0.0003 0.0003
Onchocerca volvulus 0.0013 0 0.0005
Echinococcus granulosus segment polarity protein dishevelled 0.0018 0.0005 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0925
Echinococcus multilocularis histone acetyltransferase MYST2 0.0054 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0077 0.0067 0.0067
Schistosoma mansoni calpain (C02 family) 0.0038 0.0026 0.0026
Leishmania major kinesin, putative 0.0038 0.0026 0.3651
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0003 0.0003
Onchocerca volvulus Bile acid receptor homolog 0.0013 0 0.0005
Echinococcus granulosus calpain A 0.0134 0.0127 0.0127
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0187 0.0183 0.0183
Schistosoma mansoni Hyaluronidase 0.9542 1 1
Brugia malayi MH2 domain containing protein 0.0016 0.0003 0.0003
Echinococcus granulosus calpain 7 C02 family 0.0038 0.0026 0.0026
Schistosoma mansoni ferritin 0.0017 0.0005 0.0005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0055 0.0055
Schistosoma mansoni calpain C (C02 family) 0.0038 0.0026 0.0026
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0015 0.0633
Onchocerca volvulus 0.009 0.008 0.2141
Brugia malayi calpain family protein 1 0.0128 0.012 0.012
Trypanosoma brucei ISWI complex protein 0.0031 0.0019 0.2883
Plasmodium vivax aspartyl protease, putative 0.0109 0.0101 0.8242
Schistosoma mansoni hypothetical protein 0.0204 0.0201 0.0201
Plasmodium falciparum plasmepsin VI 0.0129 0.0122 1
Echinococcus multilocularis Smad4 0.0016 0.0003 0.0003
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0054 0.0043 0.0043
Echinococcus multilocularis beta LACTamase domain containing family member 0.0073 0.0063 0.0063
Trypanosoma brucei calpain-like protein, putative 0.0038 0.0026 0.3897
Loa Loa (eye worm) MBCTL1 0.0054 0.0043 0.0043
Onchocerca volvulus 0.0073 0.0063 0.1685
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0015 0.0633
Schistosoma mansoni bromodomain containing protein 0.0132 0.0125 0.0125
Onchocerca volvulus Protein ultraspiracle homolog 0.0013 0 0.0005
Onchocerca volvulus 0.0073 0.0063 0.1685
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0006 0.0006
Brugia malayi RNA binding protein 0.013 0.0123 0.0123
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0109 0.0101 0.0101
Echinococcus multilocularis regulator of G protein signaling 7 0.0018 0.0005 0.0005
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0134 0.0127 0.0127
Trypanosoma cruzi ISWI complex protein 0.0031 0.0019 0.2894
Schistosoma mansoni apoferritin-2 0.0017 0.0005 0.0005
Schistosoma mansoni dishevelled 0.0018 0.0005 0.0005
Echinococcus multilocularis calpain 5 0.0038 0.0026 0.0026
Onchocerca volvulus 0.0235 0.0233 0.6205
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0015 0.0633
Echinococcus granulosus regulator of G protein signaling 7 0.0018 0.0005 0.0005
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0109 0.0101 0.0101
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0073 0.0063 0.0063
Leishmania major hypothetical protein, conserved 0.0073 0.0063 0.9417
Schistosoma mansoni fyve finger-containing phosphoinositide kinase fyv1 0.0018 0.0005 0.0005
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0015 0.0633
Plasmodium vivax hypothetical protein, conserved 0.002 0.0007 0.0349
Schistosoma mansoni dishevelled 0.0018 0.0005 0.0005
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0925
Brugia malayi Smad1 0.0016 0.0003 0.0003
Loa Loa (eye worm) bromodomain containing protein 0.0036 0.0025 0.0025
Plasmodium vivax ataxin-2 like protein, putative 0.0077 0.0067 0.5409
Trypanosoma brucei calpain-like protein, putative 0.0038 0.0026 0.3897
Loa Loa (eye worm) calpain 5 0.0038 0.0026 0.0026
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0038 0.0026 0.3907
Brugia malayi F/Y-rich N-terminus family protein 0.0014 0.0001 0.0001
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0006 0.094
Plasmodium falciparum plasmepsin IX 0.0109 0.0101 0.8242
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0015 0.0633
Brugia malayi calpain family protein 1 0.0128 0.012 0.012
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0029 0.0017 0.0017
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0011 0.1049
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0006 0.0279
Echinococcus multilocularis calpain 0.0038 0.0026 0.0026
Schistosoma mansoni hypothetical protein 0.0095 0.0086 0.0086
Brugia malayi mbt repeat family protein 0.0047 0.0036 0.0036
Echinococcus multilocularis dnaJ subfamily B 0.0407 0.0414 0.0414
Mycobacterium leprae Probable lipase LipE 0.0073 0.0063 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0018 0.1287
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0073 0.0063 0.1275
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.002 0.0007 0.0087
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0027 0.0015 0.0633
Loa Loa (eye worm) hypothetical protein 0.0047 0.0036 0.0036
Trypanosoma brucei unspecified product 0.0019 0.0006 0.0925
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0027 0.0015 0.0015
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0007 0.0294
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0063 0.2716
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0003 0.0003
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0134 0.0127 0.0127
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0063 0.2716
Echinococcus granulosus dna polymerase eta 0.0019 0.0006 0.0006
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0038 0.0026 0.3907
Echinococcus granulosus methyl CpG binding domain protein 2 0.0035 0.0023 0.0023
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0003 0.0387
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.024 0.0239 0.0239
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0054 0.0043 0.0043
Echinococcus granulosus segment polarity protein dishevelled 0.0018 0.0005 0.0005
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0038 0.0026 0.3907
Loa Loa (eye worm) aspartyl protease 6 0.0109 0.0101 0.0101
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0006 0.0006
Brugia malayi beta-lactamase 0.0073 0.0063 0.0063
Mycobacterium leprae conserved hypothetical protein 0.002 0.0007 0.0372
Mycobacterium tuberculosis Probable lipase LipD 0.0073 0.0063 0.1275
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0006 0.0076
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0027 0.0015 0.0633
Schistosoma mansoni hypothetical protein 0.0511 0.0523 0.0523
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0007 0.0294
Mycobacterium leprae conserved hypothetical protein 0.0073 0.0063 1
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0134 0.0127 0.0127
Plasmodium vivax aspartyl proteinase, putative 0.0109 0.0101 0.8242
Loa Loa (eye worm) hypothetical protein 0.009 0.008 0.008
Schistosoma mansoni methyl-cpg binding protein mbd 0.0035 0.0023 0.0023
Brugia malayi beta-lactamase family protein 0.0073 0.0063 0.0063
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0047 0.0036 0.0036
Loa Loa (eye worm) Smad1 0.0016 0.0003 0.0003
Brugia malayi isocitrate dehydrogenase 0.0016 0.0003 0.0003
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0128 0.012 0.012
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0109 0.0101 0.0101
Brugia malayi MH1 domain containing protein 0.0016 0.0003 0.0003
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.024 0.0239 0.0239
Echinococcus multilocularis SAM and MBT domain containing protein 0.0047 0.0036 0.0036
Plasmodium falciparum plasmepsin III 0.0109 0.0101 0.8242
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0063 0.0063
Plasmodium falciparum plasmepsin VII 0.0109 0.0101 0.8242
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0029 0.0017 0.0017
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0083 0.0073 0.0073
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0003 0.0003
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0038 0.0026 0.3897
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0038 0.0026 0.3651
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0095 0.0086 0.0086
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0027 0.0015 0.0633
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0006 0.0279
Mycobacterium ulcerans hypothetical protein 0.0073 0.0063 1
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0048 0.0037 0.0037
Schistosoma mansoni smad1 5 8 and 0.0016 0.0003 0.0003
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0006 0.0925
Loa Loa (eye worm) calpain family protein 1 0.0128 0.012 0.012
Plasmodium falciparum plasmepsin VIII, putative 0.0109 0.0101 0.8242
Plasmodium vivax aspartyl protease, putative 0.0109 0.0101 0.8242
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0006 0.0925
Echinococcus multilocularis smad 0.0016 0.0003 0.0003
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0006 0.027
Schistosoma mansoni calpain-7 (C02 family) 0.0041 0.0029 0.0029
Schistosoma mansoni Smad4 0.0016 0.0003 0.0003
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.002 0.0007 0.0372
Trypanosoma cruzi kinesin, putative 0.0038 0.0026 0.3907
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0011 0.0682
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0063 0.9441
Loa Loa (eye worm) hypothetical protein 0.0299 0.03 0.03
Brugia malayi Calcitonin receptor-like protein seb-1 0.0299 0.03 0.03
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0003 0.0003
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0073 0.0063 1
Schistosoma mansoni cathepsin D (A01 family) 0.018 0.0175 0.0175
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0129 0.0122 0.0122
Loa Loa (eye worm) hypothetical protein 0.009 0.008 0.008
Brugia malayi hypothetical protein 0.0018 0.0005 0.0005
Plasmodium falciparum plasmepsin I 0.0129 0.0122 1
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0003 0.0402
Onchocerca volvulus 0.0029 0.0016 0.0436
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0015 0.0633
Schistosoma mansoni sex comb on midleg homolog 0.0047 0.0036 0.0036
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0006 0.0925
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0015 0.0633
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0003 0.0003
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0925
Echinococcus multilocularis segment polarity protein dishevelled 0.0018 0.0005 0.0005
Echinococcus granulosus histone lysine methyltransferase setb 0.0065 0.0055 0.0055
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0015 0.0633
Onchocerca volvulus 0.0047 0.0036 0.0964
Brugia malayi beta-lactamase family protein 0.0073 0.0063 0.0063
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1606 0.1672 0.1672
Echinococcus multilocularis ferritin 0.0017 0.0005 0.0005
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0015 0.0633
Loa Loa (eye worm) hypothetical protein 0.0109 0.0101 0.0101
Echinococcus multilocularis microtubule associated protein 2 0.0738 0.076 0.076
Toxoplasma gondii hypothetical protein 0.002 0.0007 0.0349
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0003 0.0003
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0006 0.0006
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0013 0 0.0005
Schistosoma mansoni tar DNA-binding protein 0.013 0.0123 0.0123
Echinococcus granulosus polycomb protein SCMH1 0.0047 0.0036 0.0036
Brugia malayi hypothetical protein 0.0018 0.0005 0.0005
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0109 0.0101 0.0101
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0016 0.0003 0.0402
Brugia malayi hypothetical protein 0.0109 0.0101 0.0101
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0007 0.0294
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0129 0.0122 0.0122
Loa Loa (eye worm) beta-lactamase 0.0073 0.0063 0.0063
Schistosoma mansoni microtubule-associated protein tau 0.0738 0.076 0.076
Plasmodium vivax SET domain protein, putative 0.003 0.0018 0.1287
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0095 0.0086 0.0086
Schistosoma mansoni dep domain containing protein 0.0018 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0054 0.0043 0.0043
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0299 0.03 0.03
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0925
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0006 0.094
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0027 0.0015 0.0633
Plasmodium vivax calpain, putative 0.0038 0.0026 0.1975
Brugia malayi latrophilin 2 splice variant baaae 0.0204 0.0201 0.0201
Schistosoma mansoni hypothetical protein 0.0095 0.0086 0.0086
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0015 0.0633
Echinococcus granulosus geminin 0.0511 0.0523 0.0523
Schistosoma mansoni myelin transcription factor 1 myt1 0.0054 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0027 0.0015 0.0015
Schistosoma mansoni tar DNA-binding protein 0.013 0.0123 0.0123
Brugia malayi mbt repeat family protein 0.0047 0.0036 0.0036
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0006 0.0006
Plasmodium vivax plasmepsin IV, putative 0.0129 0.0122 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.0063 0.0063
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0027 0.0015 0.2201
Echinococcus multilocularis L aminoadipate semialdehyde 0.0083 0.0073 0.0073
Echinococcus multilocularis calpain 7 (C02 family) 0.0038 0.0026 0.0026
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.0063 0.944
Schistosoma mansoni cpg binding protein 0.0029 0.0016 0.0016
Brugia malayi hypothetical protein 0.0109 0.0101 0.0101
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0129 0.0122 0.0122
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0018 0.0018
Onchocerca volvulus 0.0073 0.0063 0.1685
Brugia malayi Pepsin A precursor 0.0109 0.0101 0.0101
Mycobacterium tuberculosis Conserved protein 0.0073 0.0063 0.1275
Brugia malayi MH2 domain containing protein 0.0236 0.0234 0.0234
Echinococcus multilocularis calpain A 0.0134 0.0127 0.0127
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.0049 0.3931
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0027 0.0015 0.0633
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0006 0.094
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0027 0.0015 0.0015
Plasmodium vivax aspartyl proteinase, putative 0.0129 0.0122 1
Echinococcus multilocularis zinc finger protein 0.0042 0.003 0.003
Trypanosoma cruzi kinesin, putative 0.0038 0.0026 0.3907
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0034 0.0023 0.0023
Loa Loa (eye worm) TAR-binding protein 0.013 0.0123 0.0123
Schistosoma mansoni aminopeptidase P homologue (M24 family) 0.9542 1 1
Loa Loa (eye worm) hypothetical protein 0.0089 0.008 0.008
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0006 0.094
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0038 0.0026 0.3907
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0006 0.0925
Loa Loa (eye worm) hypothetical protein 0.0084 0.0074 0.0074
Mycobacterium tuberculosis Conserved protein 0.0073 0.0063 0.1275
Trypanosoma brucei PAB1-binding protein , putative 0.0077 0.0067 1
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0011 0.5
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.0005
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.0005
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0006 0.094
Trypanosoma brucei kinesin, putative 0.0038 0.0026 0.3897
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0018 0.0018
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0129 0.0122 0.522
Echinococcus granulosus calpain 5 0.0038 0.0026 0.0026
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0109 0.0101 0.0101
Echinococcus granulosus SAM and MBT domain containing protein 0.0047 0.0036 0.0036
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0029 0.0017 0.0017
Entamoeba histolytica calpain large subunit domain III containing protein 0.0038 0.0026 1
Toxoplasma gondii hypothetical protein 0.002 0.0007 0.0349
Loa Loa (eye worm) hypothetical protein 0.0073 0.0063 0.0063
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0027 0.0015 0.0633
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0011 0.1261
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0065 0.0055 0.0055
Mycobacterium ulcerans putative regulatory protein 0.002 0.0007 0.0372
Echinococcus multilocularis expressed protein 0.0017 0.0005 0.0005
Schistosoma mansoni ferritin 0.0017 0.0005 0.0005
Leishmania major DNA polymerase eta, putative 0.0019 0.0006 0.056
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0017 0.0005 0.0041
Brugia malayi Latrophilin receptor protein 2 0.0095 0.0086 0.0086
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0015 0.0633
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0029 0.0017 0.0017
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0051 0.0051
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0018 0.0005 0.0005
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0018 0.0005 0.0146
Echinococcus multilocularis bifunctional protein NCOAT 0.9542 1 1
Loa Loa (eye worm) mbt repeat family protein 0.0047 0.0036 0.0036
Brugia malayi Bromodomain containing protein 0.0156 0.015 0.015
Toxoplasma gondii aspartyl protease 0.0109 0.0101 0.8242
Onchocerca volvulus 0.0083 0.0073 0.1953
Loa Loa (eye worm) hypothetical protein 0.0073 0.0063 0.0063
Echinococcus granulosus L aminoadipate semialdehyde 0.0083 0.0073 0.0073
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0063 0.0063
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0027 0.0015 0.0633
Toxoplasma gondii ABC1 family protein 0.0073 0.0063 0.5094
Mycobacterium ulcerans putative regulatory protein 0.002 0.0007 0.0372
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0006 0.056
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0095 0.0086 0.0086
Plasmodium falciparum GAF domain-related protein, putative 0.002 0.0007 0.0349
Schistosoma mansoni hypothetical protein 0.0289 0.0289 0.0289
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0027 0.0015 0.0633
Schistosoma mansoni tar DNA-binding protein 0.013 0.0123 0.0123
Trypanosoma cruzi PAB1-binding protein , putative 0.0077 0.0067 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0095 0.0086 0.0086
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0109 0.0101 0.0101
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0034 0.0023 0.0023
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0029 0.0017 0.0017
Plasmodium falciparum plasmepsin X 0.0109 0.0101 0.8242
Brugia malayi RNA recognition motif domain containing protein 0.013 0.0123 0.0123
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0035 0.0023 0.0023
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0063 0.9441
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0006 0.027
Mycobacterium ulcerans beta-lactamase 0.0073 0.0063 1
Plasmodium vivax plasmepsin V, putative 0.0109 0.0101 0.8242
Toxoplasma gondii GAF domain-containing protein 0.002 0.0007 0.0349
Echinococcus multilocularis tar DNA binding protein 0.013 0.0123 0.0123
Loa Loa (eye worm) hyaluronidase 0.9542 1 1
Echinococcus multilocularis segment polarity protein dishevelled 0.0018 0.0005 0.0005
Plasmodium falciparum ataxin-2 like protein, putative 0.0077 0.0067 0.5409
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0299 0.03 0.03
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0029 0.0017 0.0017
Trypanosoma brucei antigen, putative 0.0038 0.0026 0.3897
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0027 0.0015 0.2188
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0006 0.2406
Toxoplasma gondii hypothetical protein 0.002 0.0007 0.0349
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0006 0.0925
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0027 0.0015 0.2201
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0029 0.0017 0.0017
Brugia malayi Pre-SET motif family protein 0.0206 0.0203 0.0203
Plasmodium vivax hypothetical protein, conserved 0.0073 0.0063 0.5094
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0027 0.0015 0.0015
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0054 0.0043 0.0043
Schistosoma mansoni hypothetical protein 0.0095 0.0086 0.0086
Brugia malayi aspartic protease BmAsp-2, identical 0.0109 0.0101 0.0101
Loa Loa (eye worm) PHD-finger family protein 0.0042 0.0031 0.0031
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0038 0.0026 0.3651
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0003 0.0387
Schistosoma mansoni regulator of G protein signaling 0.0018 0.0005 0.0005
Giardia lamblia DINP protein human, muc B family 0.0019 0.0006 0.5
Schistosoma mansoni hypothetical protein 0.0511 0.0523 0.0523
Echinococcus granulosus ferritin 0.0017 0.0005 0.0005
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0029 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0073 0.0063 0.0063
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0063 0.2716
Entamoeba histolytica protein kinase, putative 0.0038 0.0026 1
Brugia malayi N-terminal motif family protein 0.0371 0.0375 0.0375
Brugia malayi PHD-finger family protein 0.0053 0.0042 0.0042
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0038 0.0026 0.3907
Mycobacterium tuberculosis Probable esterase LipL 0.0073 0.0063 0.1275
Schistosoma mansoni hypothetical protein 0.0031 0.0019 0.0019
Schistosoma mansoni ferritin light chain 0.0017 0.0005 0.0005
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0187 0.0183 0.0183
Schistosoma mansoni smad 0.0016 0.0003 0.0003
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0018 0.0005 0.0005
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0073 0.0063 0.1275
Echinococcus multilocularis regulator of G protein signaling 7 0.0018 0.0005 0.0005
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0011 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0016 0.0016
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0048 0.0037 0.0037
Onchocerca volvulus 0.0018 0.0005 0.0146
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0006 0.0076
Plasmodium falciparum ataxin-2 like protein, putative 0.0077 0.0067 0.5409
Schistosoma mansoni calpain-7 (C02 family) 0.0041 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0095 0.0086 0.0086
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0017 0.0005 0.0041
Loa Loa (eye worm) calpain 0.0038 0.0026 0.0026
Schistosoma mansoni ferritin 0.0017 0.0005 0.0005
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0027 0.0015 0.0633
Brugia malayi hypothetical protein 0.0077 0.0067 0.0067
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0006 0.0006

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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