Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.0361 | 0.0357 |
Echinococcus granulosus | smad | 0.0027 | 0.0011 | 0.0011 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0044 | 0.0132 | 0.0128 |
Mycobacterium ulcerans | polyprenyl synthetase IdsB | 0.0498 | 0.3247 | 0.2994 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.004 | 0.0101 | 0.0101 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.007 | 0.0309 | 0.0309 |
Echinococcus granulosus | Smad4 | 0.0027 | 0.0011 | 0.0011 |
Leishmania major | cathepsin L-like protease | 0.0037 | 0.0083 | 0.0079 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0091 | 0.0454 | 0.045 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0141 | 0.0795 | 0.0791 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0037 | 0.0083 | 0.0079 |
Schistosoma mansoni | microtubule-associated protein tau | 0.1412 | 0.9516 | 0.9516 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0174 | 0.1021 | 0.0858 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.026 | 0.026 |
Schistosoma mansoni | geranylgeranyl pyrophosphate synthase | 0.0754 | 0.5002 | 0.5002 |
Leishmania major | cathepsin L-like protease | 0.0141 | 0.0795 | 0.0791 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0037 | 0.0083 | 0.0083 |
Trichomonas vaginalis | geranylgeranyl pyrophosphate synthase, putative | 0.1482 | 1 | 1 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0108 | 0.0572 | 0.0568 |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0083 | 0.0079 |
Schistosoma mansoni | smad1 5 8 and | 0.0027 | 0.0011 | 0.0011 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0078 | 0.0361 | 0.0357 |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0083 | 0.0079 |
Schistosoma mansoni | smad | 0.0027 | 0.0011 | 0.0011 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0112 | 0.0596 | 0.0596 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0027 | 0.0011 | 0.0011 |
Leishmania major | farnesyl pyrophosphate synthase | 0.1482 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0083 | 0.0079 |
Loa Loa (eye worm) | cysteine protease | 0.0037 | 0.0083 | 0.0079 |
Trypanosoma cruzi | solanesyl-diphosphate synthase | 0.0667 | 0.4405 | 0.4403 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0156 | 0.09 | 0.0896 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.007 | 0.0309 | 0.0309 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0112 | 0.0596 | 0.0592 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.0795 | 0.0791 |
Schistosoma mansoni | trans-prenyltransferase | 0.0667 | 0.4405 | 0.4405 |
Schistosoma mansoni | lamin | 0.0116 | 0.0628 | 0.0628 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0037 | 0.0083 | 0.0079 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.033 | 0.2091 | 0.2088 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0165 | 0.0161 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0141 | 0.0795 | 0.0791 |
Leishmania major | cathepsin L-like protease | 0.0037 | 0.0083 | 0.0079 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0108 | 0.0572 | 0.0572 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0052 | 0.0186 | 0.0104 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0067 | 0.0286 | 0.0286 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0144 | 0.0816 | 0.0813 |
Trypanosoma cruzi | polyprenyl synthase, putative | 0.0754 | 0.5002 | 0.5 |
Brugia malayi | Bromodomain containing protein | 0.0046 | 0.0147 | 0.0143 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0141 | 0.0795 | 0.0791 |
Brugia malayi | Polyprenyl synthetase family protein | 0.0667 | 0.4405 | 0.4403 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0027 | 0.0011 | 0.0011 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0027 | 0.0013 | 0.0009 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.026 | 0.026 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.02 | 0.0196 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0067 | 0.0286 | 0.0282 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0037 | 0.0083 | 0.0079 |
Brugia malayi | beta-lactamase family protein | 0.0108 | 0.0572 | 0.0568 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0078 | 0.0361 | 0.0794 |
Echinococcus granulosus | intermediate filament protein | 0.0116 | 0.0628 | 0.0628 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0108 | 0.0572 | 0.0493 |
Loa Loa (eye worm) | hypothetical protein | 0.0116 | 0.0628 | 0.0624 |
Trypanosoma cruzi | solanesyl-diphosphate synthase, putative | 0.0667 | 0.4405 | 0.4403 |
Schistosoma mansoni | farnesyl pyrophosphate synthase | 0.1482 | 1 | 1 |
Schistosoma mansoni | smad1 5 8 and | 0.0027 | 0.0011 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0572 | 0.0568 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0046 | 0.0147 | 0.0143 |
Echinococcus granulosus | cathepsin l1 | 0.0037 | 0.0083 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.018 | 0.0176 |
Echinococcus granulosus | GPCR family 2 | 0.0067 | 0.0286 | 0.0286 |
Schistosoma mansoni | zinc finger protein | 0.0026 | 0.0005 | 0.0005 |
Mycobacterium ulcerans | hypothetical protein | 0.0108 | 0.0572 | 0.0218 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0286 | 0.0282 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0078 | 0.0361 | 0.0361 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.0454 | 0.0454 |
Echinococcus multilocularis | cysteine protease | 0.0037 | 0.0083 | 0.0083 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0112 | 0.0596 | 0.0243 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.033 | 0.2091 | 0.2088 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0056 | 0.0215 | 0.0215 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 0.026 | 0.0256 |
Echinococcus granulosus | lamin dm0 | 0.0116 | 0.0628 | 0.0628 |
Mycobacterium tuberculosis | Conserved protein | 0.0108 | 0.0572 | 0.0401 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.0795 | 0.0791 |
Toxoplasma gondii | cathepsin CPL | 0.0037 | 0.0083 | 0.0079 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.0795 | 0.0791 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0052 | 0.0186 | 0.0104 |
Schistosoma mansoni | lamin | 0.0116 | 0.0628 | 0.0628 |
Mycobacterium ulcerans | geranylgeranyl pyrophosphate synthase | 0.1482 | 1 | 1 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0052 | 0.0186 | 0.0182 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0046 | 0.0147 | 0.0143 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0108 | 0.0572 | 0.0568 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0052 | 0.0186 | 0.0055 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.0454 | 0.0454 |
Echinococcus multilocularis | lamin dm0 | 0.0116 | 0.0628 | 0.0628 |
Treponema pallidum | octaprenyl-diphosphate synthase | 0.0754 | 0.5002 | 1 |
Echinococcus multilocularis | geranylgeranyl pyrophosphate synthase | 0.0754 | 0.5002 | 0.5002 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0037 | 0.0083 | 0.0079 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0108 | 0.0572 | 0.0493 |
Trypanosoma cruzi | farnesyl pyrophosphate synthase, putative | 0.1482 | 1 | 1 |
Loa Loa (eye worm) | acetyltransferase | 0.0166 | 0.0968 | 0.0965 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0361 | 0.0357 |
Plasmodium vivax | octaprenyl pyrophosphate synthase, putative | 0.0667 | 0.4405 | 0.4403 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.1412 | 0.9516 | 0.9516 |
Loa Loa (eye worm) | hypothetical protein | 0.0144 | 0.0816 | 0.0813 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0052 | 0.0186 | 0.0182 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.0795 | 0.0791 |
Leishmania major | cathepsin L-like protease | 0.0037 | 0.0083 | 0.0079 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.008 | 0.008 |
Leishmania major | cathepsin L-like protease | 0.0037 | 0.0083 | 0.0079 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0062 | 0.0257 | 0.0253 |
Echinococcus multilocularis | cysteine protease | 0.0037 | 0.0083 | 0.0083 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0056 | 0.0217 | 0.0213 |
Schistosoma mansoni | smad1 5 8 and | 0.0027 | 0.0011 | 0.0011 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0108 | 0.0572 | 0.0493 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0037 | 0.0083 | 0.0083 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0286 | 0.0286 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0111 | 0.0588 | 0.0585 |
Onchocerca volvulus | 0.0116 | 0.0628 | 1 | |
Brugia malayi | MH2 domain containing protein | 0.0389 | 0.2499 | 0.2496 |
Brugia malayi | MH1 domain containing protein | 0.0027 | 0.0011 | 0.0007 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.02 | 0.0196 |
Plasmodium vivax | hypothetical protein, conserved | 0.0108 | 0.0572 | 0.0568 |
Loa Loa (eye worm) | intermediate filament protein | 0.0116 | 0.0628 | 0.0624 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0027 | 0.0011 | 0.0011 |
Trichomonas vaginalis | esterase, putative | 0.0108 | 0.0572 | 0.0493 |
Giardia lamblia | Farnesyl diphosphate synthase | 0.1482 | 1 | 1 |
Loa Loa (eye worm) | polyprenyl synthetase | 0.1482 | 1 | 1 |
Schistosoma mansoni | intermediate filament proteins | 0.0116 | 0.0628 | 0.0628 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.033 | 0.2091 | 0.2088 |
Schistosoma mansoni | glutathione synthetase | 0.0498 | 0.3247 | 0.3247 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0052 | 0.0186 | 0.0186 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0129 | 0.0711 | 0.0708 |
Onchocerca volvulus | 0.0108 | 0.0572 | 0.897 | |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0108 | 0.0572 | 0.0401 |
Mycobacterium ulcerans | hypothetical protein | 0.0174 | 0.1021 | 0.0684 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0116 | 0.0628 | 0.0624 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.0795 | 0.0791 |
Loa Loa (eye worm) | ctsf protein | 0.0037 | 0.0083 | 0.0079 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0112 | 0.0596 | 0.0243 |
Trypanosoma brucei | farnesyl pyrophosphate synthase | 0.1482 | 1 | 1 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0104 | 0.0544 | 0.0541 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0037 | 0.0083 | 0.0083 |
Trypanosoma brucei | solanesyl-diphosphate synthase, putative | 0.0667 | 0.4405 | 0.4403 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0051 | 0.0178 | 0.0377 |
Leishmania major | polyprenyl synthase, putative | 0.0754 | 0.5002 | 0.5 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0037 | 0.0083 | 0.0083 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 0.026 | 0.0256 |
Plasmodium vivax | vivapain-2 | 0.0037 | 0.0083 | 0.0079 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.021 | 0.1273 | 0.1269 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0112 | 0.0596 | 0.0596 |
Mycobacterium ulcerans | geranylgeranyl pyrophosphate synthase | 0.1482 | 1 | 1 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0078 | 0.0361 | 0.0361 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0108 | 0.0572 | 0.0401 |
Leishmania major | cysteine peptidase A (CPA) | 0.0037 | 0.0083 | 0.0079 |
Entamoeba histolytica | geranylgeranyl pyrophosphate synthase, putative | 0.0667 | 0.4405 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0286 | 0.0286 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0027 | 0.0011 | 0.0011 |
Brugia malayi | RNA binding protein | 0.0063 | 0.026 | 0.0256 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0052 | 0.0186 | 0.0182 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0052 | 0.0186 | 0.0182 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.021 | 0.1273 | 0.1269 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0108 | 0.0572 | 0.0401 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0159 | 0.0919 | 0.0919 |
Mycobacterium tuberculosis | Conserved protein | 0.0108 | 0.0572 | 0.0401 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.0795 | 0.0791 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0572 | 0.0568 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0051 | 0.0177 | 0.0095 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0052 | 0.0186 | 0.0186 |
Loa Loa (eye worm) | Smad1 | 0.0027 | 0.0011 | 0.0007 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0108 | 0.0572 | 0.0401 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0037 | 0.0083 | 0.0007 |
Echinococcus multilocularis | musashi | 0.0116 | 0.0628 | 0.0628 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0166 | 0.0968 | 0.0968 |
Brugia malayi | PHD-finger family protein | 0.0031 | 0.0045 | 0.0041 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.026 | 0.026 |
Mycobacterium tuberculosis | Conserved protein | 0.0108 | 0.0572 | 0.0401 |
Wolbachia endosymbiont of Brugia malayi | geranylgeranyl pyrophosphate synthase | 0.0667 | 0.4405 | 1 |
Entamoeba histolytica | bifunctional short chain isoprenyl diphosphate synthase, putative | 0.0498 | 0.3247 | 0.7323 |
Mycobacterium leprae | conserved hypothetical protein | 0.0108 | 0.0572 | 0.1273 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0108 | 0.0572 | 0.0401 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0116 | 0.0628 | 0.0624 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0052 | 0.0186 | 0.0186 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.021 | 0.1273 | 0.1269 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0286 | 0.0286 |
Onchocerca volvulus | 0.0108 | 0.0572 | 0.897 | |
Trichomonas vaginalis | geranylgeranyl pyrophosphate synthase, putative | 0.1482 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0037 | 0.0083 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.021 | 0.1273 | 0.1269 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0083 | 0.0079 |
Schistosoma mansoni | hypothetical protein | 0.0067 | 0.0286 | 0.0286 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0046 | 0.0147 | 0.0143 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.004 | 0.0101 | 0.0101 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0108 | 0.0572 | 0.0493 |
Toxoplasma gondii | ABC1 family protein | 0.0108 | 0.0572 | 0.0568 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0037 | 0.0083 | 0.0079 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0364 | 0.0361 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.0454 | 0.0454 |
Echinococcus multilocularis | decaprenyl diphosphate synthase subunit 1 | 0.0667 | 0.4405 | 0.4405 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0572 | 0.0568 |
Leishmania major | solanesyl-diphosphate synthase, putative | 0.0667 | 0.4405 | 0.4403 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0052 | 0.0186 | 0.0182 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0166 | 0.0968 | 0.0965 |
Loa Loa (eye worm) | geranylgeranyl pyrophosphate synthetase | 0.0754 | 0.5002 | 0.5 |
Toxoplasma gondii | hypothetical protein | 0.0027 | 0.0013 | 0.0009 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0037 | 0.0083 | 0.0079 |
Brugia malayi | MAP kinase sur-1 | 0.0052 | 0.0186 | 0.0182 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0141 | 0.0795 | 0.0791 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0051 | 0.0177 | 0.0177 |
Echinococcus multilocularis | GPCR, family 2 | 0.0067 | 0.0286 | 0.0286 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0052 | 0.0186 | 0.0182 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.008 | 0.008 |
Trypanosoma cruzi | farnesyl pyrophosphate synthase | 0.1482 | 1 | 1 |
Mycobacterium tuberculosis | Probable polyprenyl-diphosphate synthase GrcC1 (polyprenyl pyrophosphate synthetase) | 0.0169 | 0.0988 | 0.0824 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0052 | 0.0186 | 0.0182 |
Leishmania major | cathepsin L-like protease | 0.0141 | 0.0795 | 0.0791 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.0454 | 0.0454 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0166 | 0.0968 | 0.0968 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0389 | 0.2499 | 0.2496 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0027 | 0.0011 | 0.0011 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0108 | 0.0572 | 0.0218 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0067 | 0.0286 | 0.0286 |
Mycobacterium ulcerans | polyprenyl diphosphate synthetase, GrcC1 | 0.0667 | 0.4405 | 0.4196 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0046 | 0.0147 | 0.0143 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0108 | 0.0572 | 0.0568 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.026 | 0.026 |
Brugia malayi | MH1 domain containing protein | 0.0027 | 0.0011 | 0.0007 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0051 | 0.0177 | 0.0173 |
Brugia malayi | beta-lactamase | 0.0108 | 0.0572 | 0.0568 |
Trichomonas vaginalis | geranylgeranyl diphosphate synthase, putative | 0.1482 | 1 | 1 |
Loa Loa (eye worm) | beta-lactamase | 0.0108 | 0.0572 | 0.0568 |
Plasmodium falciparum | octaprenyl pyrophosphate synthase | 0.0667 | 0.4405 | 0.4403 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0027 | 0.0013 | 0.0009 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.0795 | 0.0791 |
Leishmania major | hypothetical protein, conserved | 0.0108 | 0.0572 | 0.0568 |
Trypanosoma cruzi | solanesyl-diphosphate synthase, putative | 0.0667 | 0.4405 | 0.4403 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0215 | 0.0211 |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0083 | 0.0079 |
Plasmodium vivax | geranylgeranyl pyrophosphate synthase | 0.1482 | 1 | 1 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0108 | 0.0572 | 0.0401 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0572 | 0.0568 |
Echinococcus granulosus | prenyl decaprenyl diphosphate synthase | 0.0498 | 0.3247 | 0.3247 |
Toxoplasma gondii | polyprenyl synthetase superfamily protein | 0.1482 | 1 | 1 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0691 | 0.4573 | 0.4475 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0067 | 0.0286 | 0.0286 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0056 | 0.0215 | 0.0215 |
Brugia malayi | MH2 domain containing protein | 0.0027 | 0.0011 | 0.0007 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0078 | 0.0361 | 0.0357 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0108 | 0.0572 | 0.0493 |
Mycobacterium ulcerans | beta-lactamase | 0.0108 | 0.0572 | 0.0218 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.0795 | 0.0791 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0112 | 0.0596 | 0.0592 |
Echinococcus multilocularis | smad | 0.0027 | 0.0011 | 0.0011 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0389 | 0.2499 | 0.2496 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.0361 | 0.0699 |
Echinococcus granulosus | microtubule associated protein 2 | 0.1412 | 0.9516 | 0.9516 |
Echinococcus granulosus | geranylgeranyl pyrophosphate synthase | 0.0754 | 0.5002 | 0.5002 |
Schistosoma mansoni | hypothetical protein | 0.0144 | 0.0816 | 0.0816 |
Leishmania major | mitochondrial DNA polymerase beta | 0.033 | 0.2091 | 0.2088 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0156 | 0.09 | 0.0896 |
Onchocerca volvulus | 0.0108 | 0.0572 | 0.897 | |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0108 | 0.0572 | 0.0572 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0108 | 0.0572 | 0.0572 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0037 | 0.0083 | 0.0083 |
Brugia malayi | intermediate filament protein | 0.0116 | 0.0628 | 0.0624 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0037 | 0.0083 | 0.0083 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0108 | 0.0572 | 0.0218 |
Brugia malayi | TAR-binding protein | 0.0063 | 0.026 | 0.0256 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.0613 | 0.061 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.008 | 0.008 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0052 | 0.0186 | 0.0104 |
Mycobacterium tuberculosis | Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate | 0.0498 | 0.3247 | 0.3125 |
Plasmodium vivax | vivapain-2 | 0.0037 | 0.0083 | 0.0079 |
Brugia malayi | Bromodomain containing protein | 0.0087 | 0.0424 | 0.042 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.0795 | 0.0791 |
Echinococcus granulosus | farnesyl pyrophosphate synthase | 0.1482 | 1 | 1 |
Mycobacterium leprae | PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) | 0.0667 | 0.4405 | 1 |
Wolbachia endosymbiont of Brugia malayi | geranylgeranyl pyrophosphate synthase | 0.0498 | 0.3247 | 0.7136 |
Brugia malayi | Probable ClpP-like protease | 0.0078 | 0.0361 | 0.0357 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 0.026 | 0.0256 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0051 | 0.0177 | 0.0173 |
Brugia malayi | geranylgeranyl pyrophosphate synthetase | 0.0754 | 0.5002 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.0795 | 0.0791 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0572 | 0.0568 |
Mycobacterium ulcerans | lipase LipD | 0.0108 | 0.0572 | 0.0218 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0037 | 0.0083 | 0.0083 |
Echinococcus multilocularis | prenyl (decaprenyl) diphosphate synthase | 0.0498 | 0.3247 | 0.3247 |
Mycobacterium tuberculosis | Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) | 0.1482 | 1 | 1 |
Toxoplasma gondii | polyprenyl synthetase superfamily protein | 0.0667 | 0.4405 | 0.4403 |
Brugia malayi | hypothetical protein | 0.0036 | 0.008 | 0.0076 |
Echinococcus multilocularis | lamin | 0.0116 | 0.0628 | 0.0628 |
Loa Loa (eye worm) | fibroinase | 0.0037 | 0.0083 | 0.0079 |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 0.026 | 0.026 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0156 | 0.09 | 0.0896 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0052 | 0.0186 | 0.0186 |
Chlamydia trachomatis | geranylgeranyl pyrophosphate synthase | 0.0498 | 0.3247 | 1 |
Echinococcus multilocularis | zinc finger protein | 0.0026 | 0.0005 | 0.0005 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 0.026 | 0.026 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0067 | 0.0286 | 0.0286 |
Schistosoma mansoni | bromodomain containing protein | 0.0074 | 0.0336 | 0.0336 |
Echinococcus granulosus | decaprenyl diphosphate synthase subunit 1 | 0.0667 | 0.4405 | 0.4405 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0051 | 0.0178 | 0.0178 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.0454 | 0.0454 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0027 | 0.0011 | 0.0007 |
Mycobacterium tuberculosis | Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) | 0.0498 | 0.3247 | 0.3125 |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 0.026 | 0.0256 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0078 | 0.0361 | 0.0361 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0051 | 0.0178 | 0.0178 |
Mycobacterium tuberculosis | Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) | 0.0498 | 0.3247 | 0.3125 |
Onchocerca volvulus | 0.0116 | 0.0628 | 1 | |
Trichomonas vaginalis | CMGC family protein kinase | 0.0052 | 0.0186 | 0.0104 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0112 | 0.0596 | 0.0596 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0108 | 0.0572 | 0.0572 |
Brugia malayi | MH2 domain containing protein | 0.0027 | 0.0011 | 0.0007 |
Echinococcus multilocularis | farnesyl pyrophosphate synthase | 0.1482 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0083 | 0.0079 |
Trypanosoma brucei | protein kinase, putative | 0.0052 | 0.0186 | 0.0182 |
Loa Loa (eye worm) | polyprenyl synthetase | 0.0667 | 0.4405 | 0.4403 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0067 | 0.0286 | 0.0282 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0091 | 0.0454 | 0.045 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.012 | 0.0116 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0051 | 0.0177 | 0.0173 |
Leishmania major | cathepsin L-like protease | 0.0141 | 0.0795 | 0.0791 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.026 | 0.026 |
Trypanosoma cruzi | polyprenyl synthase, putative | 0.0754 | 0.5002 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.0454 | 0.0454 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.0454 | 0.0454 |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0083 | 0.0079 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0067 | 0.0286 | 0.0282 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0027 | 0.0011 | 0.0007 |
Leishmania major | cathepsin L-like protease | 0.0037 | 0.0083 | 0.0079 |
Entamoeba histolytica | geranylgeranyl pyrophosphate synthetase, putative | 0.0667 | 0.4405 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0572 | 0.0568 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0044 | 0.0132 | 0.012 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0052 | 0.0186 | 0.0182 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0037 | 0.0083 | 0.0083 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0062 | 0.0257 | 0.0253 |
Echinococcus multilocularis | Smad4 | 0.0027 | 0.0011 | 0.0011 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0108 | 0.0572 | 0.0568 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.008 | 0.008 |
Mycobacterium leprae | Probable lipase LipE | 0.0108 | 0.0572 | 0.1273 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.0795 | 0.0791 |
Echinococcus granulosus | zinc finger protein | 0.0026 | 0.0005 | 0.0005 |
Echinococcus granulosus | lamin | 0.0116 | 0.0628 | 0.0628 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0112 | 0.0596 | 0.0425 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0052 | 0.0186 | 0.0182 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0051 | 0.0177 | 0.0095 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0037 | 0.0083 | 0.0007 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0108 | 0.0572 | 0.0401 |
Entamoeba histolytica | cysteine protease, putative | 0.0037 | 0.0083 | 0.0007 |
Brugia malayi | Smad1 | 0.0027 | 0.0011 | 0.0007 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0078 | 0.0361 | 0.0357 |
Plasmodium falciparum | geranylgeranyl pyrophosphate synthase, putative | 0.1482 | 1 | 1 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0052 | 0.0186 | 0.0186 |
Toxoplasma gondii | hypothetical protein | 0.0053 | 0.0194 | 0.019 |
Schistosoma mansoni | Smad4 | 0.0027 | 0.0011 | 0.0011 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0108 | 0.0572 | 0.0568 |
Brugia malayi | beta-lactamase family protein | 0.0108 | 0.0572 | 0.0568 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.