Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.032 | 0.3438 | 0.3438 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.032 | 0.3438 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0899 | 1 | 1 |
Schistosoma mansoni | brg-1 associated factor | 0.0899 | 1 | 1 |
Brugia malayi | SWIB/MDM2 domain containing protein | 0.0899 | 1 | 1 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0041 | 0.0285 | 1 |
Echinococcus granulosus | SWI:SNF matrix associated | 0.0899 | 1 | 1 |
Schistosoma mansoni | RNA binding protein | 0.032 | 0.3438 | 0.3438 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.032 | 0.3438 | 1 |
Echinococcus granulosus | Zinc finger RanBP2 type | 0.032 | 0.3438 | 0.3438 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.032 | 0.3438 | 1 |
Trypanosoma brucei | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.032 | 0.3438 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0899 | 1 | 1 |
Schistosoma mansoni | zinc finger protein | 0.032 | 0.3438 | 0.3438 |
Toxoplasma gondii | Zn-finger in Ran binding protein and others domain-containing protein | 0.032 | 0.3438 | 0.3438 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0045 | 0.0328 | 0.0328 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0045 | 0.0328 | 0.0328 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.032 | 0.3438 | 0.3438 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0041 | 0.0285 | 1 |
Brugia malayi | brahma associated protein 60 kDa | 0.0899 | 1 | 1 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0899 | 1 | 1 |
Echinococcus multilocularis | Nuclear pore complex protein Nup153 | 0.032 | 0.3438 | 0.3438 |
Loa Loa (eye worm) | hypothetical protein | 0.032 | 0.3438 | 0.3438 |
Chlamydia trachomatis | SWIB complex protein | 0.0899 | 1 | 0.5 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0899 | 1 | 1 |
Loa Loa (eye worm) | brahma associated protein | 0.0899 | 1 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.032 | 0.3438 | 1 |
Schistosoma mansoni | TRABID protein (C64 family) | 0.032 | 0.3438 | 0.3438 |
Onchocerca volvulus | 0.032 | 0.3438 | 0.3438 | |
Chlamydia trachomatis | DNA topoisomerase I | 0.0899 | 1 | 0.5 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0045 | 0.0328 | 0.0328 |
Toxoplasma gondii | ran binding protein | 0.032 | 0.3438 | 0.3438 |
Leishmania major | hypothetical protein, conserved | 0.032 | 0.3438 | 1 |
Echinococcus multilocularis | Zinc finger, RanBP2 type | 0.032 | 0.3438 | 0.3438 |
Echinococcus granulosus | ring and YY1 binding protein | 0.032 | 0.3438 | 0.3438 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0899 | 1 | 1 |
Toxoplasma gondii | SWIB/MDM2 domain-containing protein | 0.0899 | 1 | 1 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.032 | 0.3438 | 0.3438 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0899 | 1 | 1 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0154 | 0.1557 | 0.1557 |
Trypanosoma brucei | mitochondrial RNA binding complex 1 subunit | 0.032 | 0.3438 | 1 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0045 | 0.0328 | 0.0328 |
Loa Loa (eye worm) | hypothetical protein | 0.032 | 0.3438 | 0.3438 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.032 | 0.3438 | 0.3438 |
Schistosoma mansoni | hypothetical protein | 0.032 | 0.3438 | 0.3438 |
Onchocerca volvulus | Ubiquitin thioesterase ZRANB1 homolog | 0.032 | 0.3438 | 0.3438 |
Leishmania major | hypothetical protein, conserved | 0.032 | 0.3438 | 1 |
Onchocerca volvulus | 0.032 | 0.3438 | 0.3438 | |
Echinococcus multilocularis | zinc finger protein Ran binding | 0.032 | 0.3438 | 0.3438 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0899 | 1 | 1 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0045 | 0.0328 | 0.0328 |
Onchocerca volvulus | 0.0899 | 1 | 1 | |
Echinococcus granulosus | Nuclear pore complex protein Nup153 | 0.032 | 0.3438 | 0.3438 |
Loa Loa (eye worm) | acetyltransferase | 0.0154 | 0.1557 | 0.1557 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.032 | 0.3438 | 1 |
Echinococcus multilocularis | ring and YY1 binding protein | 0.032 | 0.3438 | 0.3438 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0149 | 0.1508 | 0.1508 |
Onchocerca volvulus | 0.032 | 0.3438 | 0.3438 | |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0154 | 0.1557 | 0.1557 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.032 | 0.3438 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.032 | 0.3438 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.032 | 0.3438 | 1 |
Leishmania major | hypothetical protein, conserved | 0.032 | 0.3438 | 1 |
Echinococcus multilocularis | Upstream activation factor subunit UAF30 | 0.0899 | 1 | 1 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.032 | 0.3438 | 1 |
Plasmodium vivax | SWIB/MDM2 domain-containing protein, putative | 0.0899 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.032 | 0.3438 | 0.3438 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.032 | 0.3438 | 1 |
Plasmodium falciparum | zinc finger Ran-binding domain-containing protein 2, putative | 0.032 | 0.3438 | 0.3438 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.032 | 0.3438 | 0.3438 |
Leishmania major | hypothetical protein, conserved | 0.032 | 0.3438 | 1 |
Echinococcus granulosus | Upstream activation factor subunit UAF30 | 0.0899 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.032 | 0.3438 | 0.3438 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.032 | 0.3438 | 1 |
Loa Loa (eye worm) | SWIB/MDM2 domain-containing protein | 0.0899 | 1 | 1 |
Schistosoma mansoni | fusion | 0.032 | 0.3438 | 0.3438 |
Echinococcus granulosus | zinc finger protein Ran binding | 0.032 | 0.3438 | 0.3438 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0045 | 0.0328 | 0.0328 |
Schistosoma mansoni | hypothetical protein | 0.0899 | 1 | 1 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0154 | 0.1557 | 0.1557 |
Schistosoma mansoni | hypothetical protein | 0.0899 | 1 | 1 |
Onchocerca volvulus | 0.032 | 0.3438 | 0.3438 | |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.032 | 0.3438 | 1 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0041 | 0.0285 | 0.0285 |
Toxoplasma gondii | DNA topoisomerase domain-containing protein | 0.0899 | 1 | 1 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0899 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.032 | 0.3438 | 1 |
Brugia malayi | YY1-associated factor 2 | 0.032 | 0.3438 | 0.3438 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.