Detailed information for compound 573425

Basic information

Technical information
  • TDR Targets ID: 573425
  • Name: oxirane-2,3-dicarboxylic acid; potassium
  • MW: 171.17 | Formula: C4H4KO5
  • H donors: 2 H acceptors: 4 LogP: -0.89 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)C1OC1C(=O)O.[K]
  • InChi: 1S/C4H4O5.K/c5-3(6)1-2(9-1)4(7)8;/h1-2H,(H,5,6)(H,7,8);
  • InChiKey: JITFNSCOWBYRSL-UHFFFAOYSA-N  

Network

Hover on a compound node to display the structore

Synonyms

  • NSC43234

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.011 0.0617 0.4464
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0157 0.0135
Mycobacterium ulcerans beta-lactamase 0.0034 0.0106 0.1725
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0027 0.0056 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0056 0.0032
Onchocerca volvulus 0.003 0.0081 0.008
Brugia malayi acetyltransferase, GNAT family protein 0.0157 0.0939 0.0959
Schistosoma mansoni polycystin 1-related 0.0019 0.0002 0.0002
Echinococcus granulosus sodium and chloride dependent glycine 0.0052 0.0229 0.0229
Onchocerca volvulus 0.0052 0.0229 0.0232
Echinococcus multilocularis E3 ubiquitin protein ligase MYLIP 0.0027 0.0056 0.0056
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0052 0.0229 0.0229
Giardia lamblia Hypothetical protein 0.0027 0.0056 0.2268
Schistosoma mansoni smad1 5 8 and 0.0033 0.0101 0.0101
Entamoeba histolytica hypothetical protein 0.0111 0.0625 1
Leishmania major hypothetical protein, conserved 0.0521 0.34 1
Schistosoma mansoni chromobox protein 0.0069 0.0342 0.0342
Trypanosoma cruzi Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Brugia malayi RING zinc finger protein 0.0027 0.0056 0.0057
Echinococcus multilocularis ring and YY1 binding protein 0.0521 0.34 0.34
Mycobacterium leprae conserved hypothetical protein 0.0034 0.0106 0.1283
Toxoplasma gondii hypothetical protein 0.0027 0.0056 0.0057
Mycobacterium ulcerans Type I modular polyketide synthase 0.0073 0.0372 0.6023
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Brugia malayi hypothetical protein 0.0027 0.0056 0.0057
Entamoeba histolytica hypothetical protein 0.0111 0.0625 1
Loa Loa (eye worm) hypothetical protein 0.0206 0.1273 0.1301
Schistosoma mansoni hypothetical protein 0.0036 0.0121 0.0121
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0079 0.041 0.1847
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0056 0.0032
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0014 0.0015
Brugia malayi Hypothetical RING finger protein C16C10.7 in chromosome III 0.0027 0.0056 0.0057
Echinococcus granulosus ring and YY1 binding protein 0.0521 0.34 0.34
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0056 0.0165
Trichomonas vaginalis esterase, putative 0.0034 0.0106 0.0084
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0014 0.0013
Onchocerca volvulus 0.0027 0.0056 0.0055
Plasmodium falciparum trophozoite exported protein 1 0.0027 0.0056 0.0057
Giardia lamblia Protein 21.1 0.0027 0.0056 0.2268
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0014 0.0014
Loa Loa (eye worm) norepinephrine transporter 0.0307 0.1955 0.1998
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0073 0.0372 0.2614
Mycobacterium tuberculosis Polyketide synthase Pks12 0.0078 0.0402 0.2846
Trypanosoma cruzi WLM domain containing protein, putative 0.0521 0.34 1
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger) containing protein, putative 0.0027 0.0056 0.0165
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0014 0.0013
Echinococcus multilocularis muscleblind protein 0.0145 0.0859 0.0859
Echinococcus granulosus inhibitor of apoptosis protein 0.0036 0.0121 0.0121
Echinococcus granulosus neuropeptide receptor A26 0.0439 0.2845 0.2845
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0052 0.0229 0.0229
Leishmania major hypothetical protein, conserved 0.0027 0.0056 0.0165
Loa Loa (eye worm) hypothetical protein 0.0034 0.0106 0.0109
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0014 0.0015
Onchocerca volvulus 0.0034 0.0106 0.0107
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0027 0.0056 0.0032
Leishmania major hypothetical protein, conserved 0.0027 0.0056 0.0165
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0106 0.0313
Loa Loa (eye worm) hypothetical protein 0.0027 0.0056 0.0057
Plasmodium vivax hypothetical protein, conserved 0.0052 0.0229 0.0234
Toxoplasma gondii hypothetical protein 0.0027 0.0056 0.0057
Schistosoma mansoni mind bomb 0.0027 0.0056 0.0056
Giardia lamblia Zinc finger domain 0.0027 0.0056 0.2268
Loa Loa (eye worm) TAR-binding protein 0.0065 0.0313 0.032
Toxoplasma gondii hypothetical protein 0.0027 0.006 0.0061
Trypanosoma brucei Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Loa Loa (eye worm) transcription factor SMAD2 0.0489 0.3183 0.3253
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0014 0.0014
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0272 0.1719 0.1719
Brugia malayi Zinc finger protein 183 homolog 0.0027 0.0057 0.0058
Loa Loa (eye worm) hypothetical protein 0.0041 0.0153 0.0157
Echinococcus granulosus peptidase Clp S14 family 0.0052 0.0226 0.0226
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0014 0.0015
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0014 0.0014
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0073 0.0372 0.2614
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0313 0.0313
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0014 0.0014
Mycobacterium ulcerans lipase LipD 0.0034 0.0106 0.1725
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0014 0.0014
Echinococcus multilocularis SWI:SNF matrix associated 0.1464 0.9785 0.9785
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0014 0.0014
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0014 0.0015
Echinococcus multilocularis chromobox protein 1 0.0069 0.0342 0.0342
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0052 0.0229 0.0234
Trypanosoma cruzi hypothetical protein, conserved 0.0521 0.34 1
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Plasmodium falciparum amino acid transporter, putative 0.0052 0.0229 0.0234
Schistosoma mansoni lipoxygenase 0.0052 0.023 0.023
Loa Loa (eye worm) hypothetical protein 0.0052 0.0229 0.0234
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0002 0.0002
Leishmania major hypothetical protein, conserved 0.0027 0.0056 0.0165
Trichomonas vaginalis penicillin-binding protein, putative 0.0034 0.0106 0.0084
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0014 0.0014
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0521 0.34 0.34
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0056 0.0165
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0048 0.0204 0.3299
Loa Loa (eye worm) hypothetical protein 0.0027 0.0056 0.0057
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger)/EF-hand domain pair, putative 0.0027 0.0056 0.0165
Mycobacterium tuberculosis Conserved protein 0.0034 0.0106 0.0615
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0056 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0056 0.0032
Echinococcus multilocularis dnaJ subfamily B 0.0828 0.5481 0.5481
Echinococcus granulosus Upstream activation factor subunit UAF30 0.1464 0.9785 0.9785
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0052 0.0229 0.0234
Onchocerca volvulus Putative RING finger protein 207 0.0027 0.0056 0.0055
Schistosoma mansoni rab6-interacting 0.0019 0.0002 0.0002
Onchocerca volvulus 0.0052 0.0229 0.0232
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0014 0.0015
Schistosoma mansoni sodium/chloride dependent transporter 0.0307 0.1955 0.1955
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0002 0.0002
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0037 0.0126 0.0129
Trichomonas vaginalis ankyrin, putative 0.0027 0.0056 0.0032
Giardia lamblia Protein 21.1 0.0027 0.0056 0.2268
Mycobacterium ulcerans thioesterase TesA 0.0061 0.0289 0.4682
Schistosoma mansoni methyltransferase-related 0.0022 0.0025 0.0025
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0133 0.0778 0.0778
Loa Loa (eye worm) hypothetical protein 0.0521 0.34 0.3475
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0123 0.071 0.071
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0036 0.0121 0.0121
Schistosoma mansoni chromobox protein 0.0069 0.0342 0.0342
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0014 0.0014
Plasmodium falciparum E3 ubiquitin-protein ligase, putative 0.0027 0.0056 0.0057
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.041 0.6641
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0313 0.0313
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0014 0.0015
Plasmodium vivax DNA repair protein RAD5, putative 0.0027 0.0056 0.0057
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0052 0.0229 0.0229
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0056 0.0032
Loa Loa (eye worm) hypothetical protein 0.0307 0.1955 0.1998
Echinococcus granulosus E3 ubiquitin protein ligase LRSAM1 0.0027 0.0056 0.0056
Trichomonas vaginalis ankyrin, putative 0.0027 0.0056 0.0032
Onchocerca volvulus 0.0128 0.0739 0.0753
Echinococcus granulosus beta LACTamase domain containing family member 0.0034 0.0106 0.0106
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0068 0.0339 0.0346
Onchocerca volvulus 0.0206 0.1273 0.13
Loa Loa (eye worm) hypothetical protein 0.0021 0.0014 0.0015
Schistosoma mansoni hypothetical protein 0.1464 0.9785 0.9785
Brugia malayi beta-lactamase family protein 0.0034 0.0106 0.0109
Brugia malayi Probable ClpP-like protease 0.0079 0.041 0.0419
Schistosoma mansoni hypothetical protein 0.0272 0.1719 0.1719
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0014 0.0014
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0313 0.0313
Brugia malayi Muscleblind-like protein 0.0145 0.0859 0.0877
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.0078 0.0402 0.6337
Loa Loa (eye worm) hypothetical protein 0.0021 0.0014 0.0015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0014 0.0015
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0137 0.0138
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0034 0.0106 0.0109
Trypanosoma brucei SNF2 family N-terminal domain/Ring finger domain containing protein, putative 0.0027 0.0056 0.0165
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0521 0.34 0.3475
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0014 0.0014
Brugia malayi Smad1 0.0033 0.0101 0.0103
Brugia malayi Neuralized family protein 0.0027 0.0056 0.0057
Leishmania major hypothetical protein, conserved 0.0027 0.0056 0.0165
Trichomonas vaginalis ion channel nompc, putative 0.0027 0.0056 0.0032
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0014 0.0013
Echinococcus granulosus chromobox protein 1 0.0069 0.0342 0.0342
Echinococcus granulosus chromobox protein 1 0.0069 0.0342 0.0342
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0521 0.34 1
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0052 0.023 0.023
Brugia malayi hypothetical protein 0.0027 0.0056 0.0057
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0002 0.0002
Echinococcus multilocularis SWI:SNF matrix associated 0.1464 0.9785 0.9785
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0014 0.0015
Mycobacterium ulcerans polyketide synthase 0.0073 0.0372 0.6023
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0521 0.34 0.34
Echinococcus granulosus sodium and chloride dependent glycine 0.0052 0.0229 0.0229
Trypanosoma cruzi WLM domain containing protein, putative 0.0521 0.34 1
Onchocerca volvulus 0.0027 0.0056 0.0055
Mycobacterium tuberculosis Conserved protein 0.0034 0.0106 0.0615
Onchocerca volvulus 0.0027 0.0056 0.0055
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0014 0.0014
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0002 0.0002
Toxoplasma gondii helicase, putative 0.0027 0.0056 0.0057
Schistosoma mansoni smad1 5 8 and 0.0033 0.0101 0.0101
Onchocerca volvulus 0.0034 0.0106 0.0107
Echinococcus granulosus smad 0.0033 0.0101 0.0101
Loa Loa (eye worm) hypothetical protein 0.0052 0.0229 0.0234
Onchocerca volvulus 0.0521 0.34 0.3474
Loa Loa (eye worm) Smad1 0.0033 0.0101 0.0103
Loa Loa (eye worm) hypothetical protein 0.0307 0.1955 0.1998
Schistosoma mansoni thyroid hormone receptor 0.0154 0.0917 0.0917
Brugia malayi MH2 domain containing protein 0.0033 0.0101 0.0103
Loa Loa (eye worm) latrophilin receptor protein 2 0.0272 0.1719 0.1757
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0157 0.0939 0.0939
Echinococcus multilocularis Smad4 0.0033 0.0101 0.0101
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Trypanosoma brucei ring finger containing protein 0.0027 0.0056 0.0165
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0052 0.0229 0.0229
Giardia lamblia Hypothetical protein 0.0027 0.0056 0.2268
Echinococcus multilocularis microtubule associated protein 2 0.1496 1 1
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0056 0.0165
Giardia lamblia Protein 21.1 0.0027 0.0056 0.2268
Brugia malayi MH2 domain containing protein 0.0489 0.3183 0.3253
Echinococcus granulosus tar DNA binding protein 0.0065 0.0313 0.0313
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0188 0.0167
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0014 0.0015
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0052 0.0229 0.0234
Loa Loa (eye worm) solute carrier family 6 member 4 0.0307 0.1955 0.1998
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0056 0.0032
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0052 0.0229 0.0229
Loa Loa (eye worm) hypothetical protein 0.0036 0.0121 0.0124
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0313 0.0313
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Schistosoma mansoni inhibitor of apoptosis protein 0.0036 0.0121 0.0121
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0014 0.0015
Toxoplasma gondii Bardet-Biedl syndrome 5, putative 0.0027 0.0056 0.0057
Schistosoma mansoni hypothetical protein 0.0027 0.0056 0.0056
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0079 0.041 0.041
Echinococcus granulosus ring finger protein 113a 0.0027 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0021 0.0014 0.0015
Trypanosoma cruzi hypothetical protein 0.0027 0.0056 0.0165
Loa Loa (eye worm) RNA binding protein 0.0065 0.0313 0.032
Onchocerca volvulus 0.0307 0.1955 0.1997
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0521 0.34 0.34
Plasmodium falciparum RING zinc finger protein, putative 0.0027 0.0056 0.0057
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0187 0.0187
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0056 0.0032
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.0078 0.0402 0.2846
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0521 0.34 0.3475
Trichomonas vaginalis ankyrin repeat domain protein, putative 0.0027 0.0056 0.0032
Giardia lamblia Protein 21.1 0.0027 0.0056 0.2268
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0014 0.0014
Giardia lamblia Protein 21.1 0.0027 0.0056 0.2268
Leishmania major hypothetical protein, conserved 0.0027 0.0056 0.0165
Mycobacterium tuberculosis Probable fatty acid synthase Fas (fatty acid synthetase) 0.0023 0.0031 0.0048
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0041 0.0017
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0036 0.0121 0.0124
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0056 0.0032
Leishmania major hypothetical protein, conserved 0.0034 0.0106 0.0313
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0033 0.0101 0.0101
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0014 0.0015
Giardia lamblia Protein 21.1 0.0027 0.0056 0.2268
Trypanosoma cruzi hypothetical protein 0.0027 0.0056 0.0165
Loa Loa (eye worm) acyl carrier protein 0.0034 0.0104 0.0106
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0056 0.0032
Trypanosoma brucei hypothetical protein, conserved 0.0521 0.34 1
Mycobacterium tuberculosis Polyketide synthetase MbtC (polyketide synthase) 0.0025 0.0046 0.0159
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.1464 0.9785 1
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0056 0.0032
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0052 0.0229 0.0234
Echinococcus multilocularis muscleblind protein 1 0.0145 0.0859 0.0859
Schistosoma mansoni sodium/chloride dependent transporter 0.0052 0.0229 0.0229
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0014 0.0015
Loa Loa (eye worm) hypothetical protein 0.0052 0.0229 0.0234
Echinococcus granulosus GPCR family 2 0.0272 0.1719 0.1719
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0041 0.0017
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Schistosoma mansoni tar DNA-binding protein 0.0065 0.0313 0.0313
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0187 0.0187
Mycobacterium ulcerans thioesterase 0.0061 0.0289 0.4682
Schistosoma mansoni smad1 5 8 and 0.0033 0.0101 0.0101
Echinococcus multilocularis sodium and chloride dependent glycine 0.0052 0.0229 0.0229
Onchocerca volvulus 0.0521 0.34 0.3474
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0056 0.0032
Trypanosoma brucei predicted zinc finger protein 0.0027 0.0056 0.0165
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.0521 0.34 0.3475
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0187 0.0187
Mycobacterium ulcerans Type I modular polyketide synthase 0.0073 0.0372 0.6023
Schistosoma mansoni rnf5 0.0027 0.0056 0.0056
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0342 0.035
Echinococcus multilocularis thyroid hormone receptor alpha 0.0154 0.0917 0.0917
Loa Loa (eye worm) hypothetical protein 0.0027 0.0056 0.0057
Giardia lamblia Protein 21.1 0.0027 0.0056 0.2268
Mycobacterium tuberculosis Polyketide synthetase MbtD (polyketide synthase) 0.0023 0.0028 0.0023
Loa Loa (eye worm) hypothetical protein 0.0307 0.1955 0.1998
Toxoplasma gondii type I fatty acid synthase, putative 0.0052 0.0229 0.0234
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0052 0.0229 0.0229
Giardia lamblia Protein 21.1 0.0027 0.0056 0.2268
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0056 0.0032
Echinococcus multilocularis mothers against decapentaplegic 5 0.0033 0.0101 0.0101
Mycobacterium ulcerans hypothetical protein 0.0034 0.0106 0.1725
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0056 0.0032
Toxoplasma gondii ABC1 family protein 0.0034 0.0106 0.0109
Echinococcus multilocularis zinc finger protein Ran binding 0.0521 0.34 0.34
Mycobacterium tuberculosis Polyketide synthase Pks13 0.011 0.0617 0.4464
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Leishmania major hypothetical protein, conserved 0.0027 0.0056 0.0165
Echinococcus multilocularis GPCR, family 2 0.0272 0.1719 0.1719
Echinococcus granulosus E3 ubiquitin protein ligase MYLIP 0.0027 0.0056 0.0056
Giardia lamblia E3 ubiquitin ligase for Rad6p required for the ubiquitination of histone H2B 0.0027 0.0056 0.2268
Echinococcus multilocularis E3 ubiquitin protein ligase LRSAM1 0.0027 0.0056 0.0056
Loa Loa (eye worm) MH2 domain-containing protein 0.0033 0.0101 0.0103
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0041 0.0017
Schistosoma mansoni peter pan-related 0.0027 0.0056 0.0056
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0065 0.0313 0.032
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0052 0.0229 0.0229
Toxoplasma gondii hypothetical protein 0.0027 0.0056 0.0057
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.1464 0.9785 1
Loa Loa (eye worm) RiNg Finger protein family member 0.0027 0.0057 0.0058
Loa Loa (eye worm) hypothetical protein 0.0052 0.0229 0.0234
Brugia malayi AMP-binding enzyme family protein 0.0023 0.0028 0.0029
Giardia lamblia Protein 21.1 0.0027 0.0056 0.2268
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0052 0.0229 0.0229
Echinococcus multilocularis tar DNA binding protein 0.0065 0.0313 0.0313
Mycobacterium tuberculosis Conserved protein 0.0034 0.0106 0.0615
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0036 0.0121 0.0121
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0137 0.0115
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0521 0.34 1
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.041 0.0419
Toxoplasma gondii type I fatty acid synthase, putative 0.0078 0.0402 0.0411
Toxoplasma gondii ran binding protein 0.0521 0.34 0.3475
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0014 0.0014
Trypanosoma brucei DNA repair protein, putative 0.0027 0.0056 0.0165
Schistosoma mansoni cpg binding protein 0.0061 0.0292 0.0292
Loa Loa (eye worm) hypothetical protein 0.0019 0.0002 0.0002
Leishmania major hypothetical protein, conserved 0.0027 0.0056 0.0165
Brugia malayi steroid hormone receptor 0.0021 0.0014 0.0015
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0079 0.041 0.0419
Giardia lamblia Protein 21.1 0.0027 0.0056 0.2268
Loa Loa (eye worm) beta-lactamase 0.0034 0.0106 0.0109
Plasmodium falciparum histone acetyltransferase GCN5 0.0042 0.0162 0.0166
Echinococcus granulosus muscleblind protein 0.0145 0.0859 0.0859
Trichomonas vaginalis conserved hypothetical protein 0.1464 0.9785 1
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0052 0.023 0.023
Echinococcus granulosus mothers against decapentaplegic 5 0.0033 0.0101 0.0101
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0056 0.0032
Schistosoma mansoni fusion 0.0521 0.34 0.34
Trichomonas vaginalis D-aminoacylase, putative 0.0034 0.0106 0.0084
Trichomonas vaginalis penicillin-binding protein, putative 0.0034 0.0106 0.0084
Echinococcus multilocularis RING finger and transmembrane domain containing protein 0.0027 0.0056 0.0056
Schistosoma mansoni sodium/chloride dependent transporter 0.0052 0.0229 0.0229
Echinococcus granulosus E3 ubiquitin protein ligase mib1 0.0027 0.0056 0.0056
Leishmania major hypothetical protein, conserved 0.0027 0.0056 0.0165
Schistosoma mansoni cellular tumor antigen P53 0.0206 0.1273 0.1273
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0014 0.0015
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0027 0.0056 0.0032
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0014 0.0015
Onchocerca volvulus 0.0521 0.34 0.3474
Plasmodium vivax E3 ubiquitin-protein ligase, putative 0.0027 0.0056 0.0057
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0034 0.0106 0.0615
Toxoplasma gondii hypothetical protein 0.0052 0.0229 0.0234
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0034 0.0106 0.0106
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0002 0.0002
Toxoplasma gondii RING zinc finger protein 0.0027 0.0056 0.0057
Echinococcus multilocularis cpg binding protein 0.0061 0.0292 0.0292
Schistosoma mansoni hypothetical protein 0.0341 0.2186 0.2186
Brugia malayi MH1 domain containing protein 0.0033 0.0101 0.0103
Schistosoma mansoni loxhd1 0.0019 0.0002 0.0002
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0027 0.0056 0.0032
Schistosoma mansoni hypothetical protein 0.0828 0.5481 0.5481
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0056 0.0032
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0002 0.0002
Mycobacterium ulcerans Type I modular polyketide synthase 0.0073 0.0372 0.6023
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0187 0.0187
Giardia lamblia Zinc finger domain 0.0027 0.0056 0.2268
Loa Loa (eye worm) RING finger protein 20 0.0027 0.0056 0.0057
Loa Loa (eye worm) hypothetical protein 0.003 0.0081 0.0082
Loa Loa (eye worm) hypothetical protein 0.0861 0.5702 0.5827
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0056 0.0032
Brugia malayi Latrophilin receptor protein 2 0.0272 0.1719 0.1757
Echinococcus granulosus cell growth regulator with ring finger domain 0.0027 0.0056 0.0056
Echinococcus multilocularis E3 ubiquitin protein ligase mib1 0.0027 0.0056 0.0056
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0041 0.0017
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0052 0.0229 0.0234
Echinococcus multilocularis smad 0.0033 0.0101 0.0101
Brugia malayi hypothetical protein 0.0027 0.0056 0.0057
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0079 0.041 0.6461
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0073 0.0372 0.2614
Brugia malayi nuclear receptor NHR-88 0.0021 0.0014 0.0015
Schistosoma mansoni smad 0.0033 0.0101 0.0101
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0014 0.0014
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0521 0.34 1
Brugia malayi CXXC zinc finger family protein 0.0058 0.0269 0.0275
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0052 0.0229 0.0229
Plasmodium falciparum zinc finger protein, putative 0.0027 0.0056 0.0057
Echinococcus multilocularis peptidase Clp (S14 family) 0.0052 0.0226 0.0226
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0041 0.0017
Brugia malayi Heterochromatin protein 1 0.0069 0.0342 0.035
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0036 0.0121 0.0124
Echinococcus granulosus zinc finger protein Ran binding 0.0521 0.34 0.34
Leishmania major DNA repair protein-like protein 0.0027 0.0056 0.0165
Plasmodium vivax trophozoite exported protein 1, putative 0.0027 0.0056 0.0057
Leishmania major hypothetical protein, conserved 0.0521 0.34 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0106 0.0109
Mycobacterium tuberculosis Probable lipase LipD 0.0034 0.0106 0.0615
Trypanosoma cruzi Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0307 0.1955 0.1998
Schistosoma mansoni hypothetical protein 0.0027 0.0056 0.0056
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.041 0.0419
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0073 0.0372 0.581
Trypanosoma cruzi hypothetical protein, conserved 0.0034 0.0106 0.0313
Brugia malayi YY1-associated factor 2 0.0521 0.34 0.3475
Giardia lamblia Kinase, NEK 0.0027 0.0056 0.2268
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0157 0.0939 0.0939
Loa Loa (eye worm) hypothetical protein 0.0052 0.0229 0.0234
Giardia lamblia Hypothetical protein 0.0027 0.0056 0.2268
Giardia lamblia Protein 21.1 0.0027 0.0056 0.2268
Echinococcus granulosus SWI:SNF matrix associated 0.1464 0.9785 0.9785
Brugia malayi MH2 domain containing protein 0.0033 0.0101 0.0103
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.006 0.0061
Loa Loa (eye worm) hypothetical protein 0.0123 0.0709 0.0724
Giardia lamblia Hypothetical protein 0.0027 0.0056 0.2268
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Schistosoma mansoni hypothetical protein 0.0272 0.1719 0.1719
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0272 0.1719 0.1719
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0052 0.0229 0.0229
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0014 0.0015
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Schistosoma mansoni lipoxygenase 0.0019 0.0002 0.0002
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0188 0.0192
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0027 0.0056 0.0032
Giardia lamblia Ribonuclease 0.0027 0.0056 0.2268
Onchocerca volvulus 0.0521 0.34 0.3474
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.1464 0.9785 1
Toxoplasma gondii hypothetical protein 0.0027 0.0056 0.0057
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0073 0.0372 0.581
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0071 0.0356 0.2499
Brugia malayi Calcitonin receptor-like protein seb-1 0.0861 0.5702 0.5827
Schistosoma mansoni serine/threonine protein kinase 0.0027 0.0056 0.0056
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.006 0.0482
Trichomonas vaginalis D-aminoacylase, putative 0.0034 0.0106 0.0084
Schistosoma mansoni ring finger protein 151 0.0027 0.0056 0.0056
Mycobacterium ulcerans esterase/lipase LipP 0.0034 0.0106 0.1725
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0059 0.0275 0.4452
Loa Loa (eye worm) hypothetical protein 0.0052 0.0229 0.0234
Brugia malayi hypothetical protein 0.0027 0.0056 0.0057
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0052 0.0229 0.0229
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0014 0.0014
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0187 0.0191
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.006 0.0061
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0078 0.0402 0.6522
Toxoplasma gondii zinc finger, C3HC4 type (RING finger) domain-containing protein 0.0027 0.0056 0.0057
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0014 0.0014
Onchocerca volvulus 0.0027 0.0056 0.0055
Brugia malayi nuclear hormone receptor 0.0021 0.0014 0.0015
Entamoeba histolytica hypothetical protein 0.0111 0.0625 1
Brugia malayi RNA recognition motif domain containing protein 0.0065 0.0313 0.032
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0056 0.0032
Chlamydia trachomatis DNA topoisomerase I 0.1464 0.9785 1
Brugia malayi B-box zinc finger family protein 0.0027 0.0056 0.0057
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0014 0.0014
Brugia malayi hypothetical protein 0.0019 0.0002 0.0002
Echinococcus multilocularis ring finger protein 113a 0.0027 0.0057 0.0057
Giardia lamblia Protein 21.1 0.0027 0.0056 0.2268
Brugia malayi latrophilin 2 splice variant baaae 0.0588 0.3858 0.3943
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Schistosoma mansoni hypothetical protein 0.0588 0.3858 0.3858
Schistosoma mansoni hypothetical protein 0.0133 0.0778 0.0778
Plasmodium falciparum E3 ubiquitin-protein ligase RNF5, putative 0.0027 0.0056 0.0057
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0056 0.0165
Toxoplasma gondii histone lysine methyltransferase SET1 0.0114 0.0647 0.0661
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0014 0.0014
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Brugia malayi MH1 domain containing protein 0.0033 0.0101 0.0103
Loa Loa (eye worm) brahma associated protein 0.1464 0.9785 1
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0079 0.041 1
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0342 0.0325
Echinococcus granulosus neuropeptide s receptor 0.0439 0.2845 0.2845
Loa Loa (eye worm) hypothetical protein 0.0021 0.0014 0.0015
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0059 0.0275 0.4155
Loa Loa (eye worm) hypothetical protein 0.0027 0.0056 0.0057
Onchocerca volvulus 0.0021 0.0014 0.0013
Trypanosoma brucei hypothetical protein, conserved 0.0034 0.0106 0.0313
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Echinococcus granulosus E3 ubiquitin protein ligase RNF146 0.0027 0.0056 0.0056
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0187 0.0187
Echinococcus multilocularis beta LACTamase domain containing family member 0.0034 0.0106 0.0106
Echinococcus multilocularis sodium and chloride dependent glycine 0.0052 0.0229 0.0229
Schistosoma mansoni microtubule-associated protein tau 0.1496 1 1
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0052 0.0226 0.1514
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0056 0.0165
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0056 0.0032
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0052 0.0229 0.0229
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0034 0.0106 0.0109
Onchocerca volvulus 0.0058 0.0269 0.0273
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0342 0.0325
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0059 0.0275 0.4452
Entamoeba histolytica acetyltransferase, GNAT family 0.0042 0.0162 0.1865
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0052 0.0229 0.0234
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0521 0.34 0.3475
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0052 0.0226 0.3318
Mycobacterium leprae Polyketide synthase Pks13 0.011 0.0617 1
Giardia lamblia Protein 21.1 0.0027 0.0056 0.2268
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0014 0.0015
Giardia lamblia Protein 21.1 0.0027 0.0056 0.2268
Echinococcus multilocularis E3 ubiquitin protein ligase Bre1 0.0027 0.0056 0.0056
Loa Loa (eye worm) MH1 domain-containing protein 0.0033 0.0101 0.0103
Trypanosoma cruzi hypothetical protein, conserved 0.0521 0.34 1
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0027 0.0056 0.0032
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0218 0.1351 1
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.1464 0.9785 1
Loa Loa (eye worm) hypothetical protein 0.0145 0.0859 0.0877
Echinococcus multilocularis ring finger protein 170 0.0027 0.0056 0.0056
Leishmania major hypothetical protein, conserved 0.0027 0.0056 0.0165
Leishmania major hypothetical protein, conserved 0.0521 0.34 1
Mycobacterium leprae Probable lipase LipE 0.0034 0.0106 0.1283
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0073 0.0372 0.038
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0034 0.0106 0.0109
Schistosoma mansoni rab6-interacting 0.0019 0.0002 0.0002
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0861 0.5702 0.5827
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0052 0.0229 0.0234
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0014 0.0014
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0052 0.0229 0.0234
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Mycobacterium leprae Probable polyketide synthase Pks1 0.0078 0.0402 0.6337
Brugia malayi brahma associated protein 60 kDa 0.1464 0.9785 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0272 0.1719 0.1719
Schistosoma mansoni coup transcription factor 0.0021 0.0014 0.0014
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0056 0.0032
Giardia lamblia Protein 21.1 0.0027 0.0056 0.2268
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0014 0.0015
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Schistosoma mansoni thyroid hormone receptor 0.0154 0.0917 0.0917
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0061 0.0289 0.4398
Echinococcus multilocularis neuropeptide receptor A26 0.0439 0.2845 0.2845
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0014 0.0014
Echinococcus multilocularis inhibitor of apoptosis protein 0.0036 0.0121 0.0121
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.006 0.0281 0.1932
Onchocerca volvulus 0.1464 0.9785 1
Plasmodium vivax amine transporter, putative 0.0052 0.0229 0.0234
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0079 0.041 0.0419
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0187 0.0187
Brugia malayi hypothetical protein 0.0052 0.0229 0.0234
Mycobacterium ulcerans fatty acid synthase Fas 0.0023 0.0031 0.0508
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0048 0.0197 0.0202
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0188 0.0167
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0036 0.0121 0.0121
Toxoplasma gondii hypothetical protein 0.0052 0.0229 0.0234
Onchocerca volvulus Fatty acid synthase homolog 0.0132 0.077 0.0785
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0041 0.0017
Echinococcus granulosus TGF beta signal transducer SmadC 0.0033 0.0101 0.0101
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0111 0.0625 0.0625
Onchocerca volvulus 0.0034 0.0106 0.0107
Mycobacterium tuberculosis Probable esterase LipL 0.0034 0.0106 0.0615
Schistosoma mansoni cpg binding protein 0.0061 0.0292 0.0292
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0014 0.0015
Toxoplasma gondii zinc finger, C3HC4 type (RING finger) domain-containing protein 0.0027 0.0056 0.0057
Giardia lamblia Kinase 0.0027 0.0056 0.2268
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0056 0.0032
Echinococcus granulosus Zinc finger RanBP2 type 0.0521 0.34 0.34
Trypanosoma brucei hypothetical protein, conserved 0.0521 0.34 1
Schistosoma mansoni zinc finger protein 0.0521 0.34 0.34
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0052 0.0226 0.1514
Echinococcus multilocularis RING finger protein 185 0.0027 0.0056 0.0056
Brugia malayi RNA binding protein 0.0065 0.0313 0.032
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0187 0.0191
Loa Loa (eye worm) hypothetical protein 0.0021 0.0014 0.0015
Loa Loa (eye worm) acetyltransferase 0.0157 0.0939 0.0959
Echinococcus granulosus tumor protein p63 0.1411 0.9425 0.9425
Brugia malayi beta-lactamase 0.0034 0.0106 0.0109
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0061 0.0037
Loa Loa (eye worm) hypothetical protein 0.0021 0.0014 0.0015
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0272 0.1719 0.1719
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0079 0.041 0.0419
Loa Loa (eye worm) hypothetical protein 0.0027 0.0056 0.0057
Loa Loa (eye worm) MH2 domain-containing protein 0.0489 0.3183 0.3253
Loa Loa (eye worm) hypothetical protein 0.0034 0.0106 0.0109
Loa Loa (eye worm) hypothetical protein 0.0521 0.34 0.3475
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0307 0.1955 0.1955
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0034 0.0106 0.0109
Plasmodium vivax RING zinc finger protein, putative 0.0027 0.0056 0.0057
Leishmania major hypothetical protein, unknown function 0.0027 0.0056 0.0165
Schistosoma mansoni transcription factor LCR-F1 0.0111 0.0625 0.0625
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0002 0.0002
Giardia lamblia Protein 21.1 0.0027 0.0056 0.2268
Schistosoma mansoni hypothetical protein 0.0111 0.0625 0.0625
Plasmodium vivax hypothetical protein, conserved 0.1464 0.9785 1
Leishmania major hypothetical protein 0.0027 0.0056 0.0165
Trichomonas vaginalis ankyrin, putative 0.0027 0.0056 0.0032
Giardia lamblia Protein 21.1 0.0027 0.0056 0.2268
Brugia malayi Zinc finger, C2H2 type family protein 0.0027 0.0056 0.0057
Loa Loa (eye worm) hypothetical protein 0.0034 0.0106 0.0109
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0034 0.0106 0.0615
Chlamydia trachomatis SWIB complex protein 0.1464 0.9785 1
Giardia lamblia Protein 21.1 0.0027 0.0056 0.2268
Brugia malayi hypothetical protein 0.0019 0.0002 0.0002
Treponema pallidum sodium- and chloride- dependent transporter 0.0307 0.1955 1
Schistosoma mansoni brg-1 associated factor 0.1464 0.9785 0.9785
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0056 0.0032
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0014 0.0015
Plasmodium falciparum transporter, putative 0.0052 0.0229 0.0234
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0056 0.0165
Brugia malayi RING finger protein 20 0.0027 0.0056 0.0057
Brugia malayi hypothetical protein 0.0027 0.0056 0.0057
Echinococcus granulosus RING finger and transmembrane domain containing protein 0.0027 0.0056 0.0056
Giardia lamblia Histone acetyltransferase GCN5 0.0042 0.0162 1
Onchocerca volvulus 0.0052 0.0229 0.0232
Brugia malayi Methyltransferase-like protein 4 0.0022 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0079 0.041 0.0419
Loa Loa (eye worm) serotonin transporter b 0.0307 0.1955 0.1998
Mycobacterium ulcerans polyketide synthase MbtD 0.0023 0.0028 0.0454
Plasmodium vivax zinc finger protein, putative 0.0027 0.0056 0.0057
Trypanosoma brucei Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0052 0.0229 0.0229
Mycobacterium ulcerans polyketide synthase 0.0078 0.0402 0.6522
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0014 0.0015
Loa Loa (eye worm) hypothetical protein 0.0021 0.0014 0.0015
Schistosoma mansoni hypothetical protein 0.0272 0.1719 0.1719
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0056 0.0032
Loa Loa (eye worm) hypothetical protein 0.0036 0.0121 0.0124
Echinococcus granulosus ring finger protein 170 0.0027 0.0056 0.0056
Schistosoma mansoni TRABID protein (C64 family) 0.0521 0.34 0.34
Brugia malayi chromobox protein homolog 3 0.0039 0.0137 0.014
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0033 0.0101 0.0101
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0056 0.0032
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0157 0.0135
Schistosoma mansoni RNA binding protein 0.0521 0.34 0.34
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0034 0.0106 0.0106
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0014 0.0015
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Giardia lamblia Protein 21.1 0.0027 0.0056 0.2268
Echinococcus multilocularis 0.0027 0.0056 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0061 0.0037
Loa Loa (eye worm) CXXC zinc finger family protein 0.0058 0.0269 0.0275
Onchocerca volvulus Protein neuralized homolog 0.0027 0.0056 0.0055
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0187 0.0187
Echinococcus granulosus RUN 0.0019 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0521 0.34 0.3475
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0056 0.0032
Mycobacterium tuberculosis Probable thioesterase TesA 0.0061 0.0289 0.199
Brugia malayi hypothetical protein 0.0111 0.0625 0.0638
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0024 0.0041 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0014 0.0015
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.0521 0.34 0.3475
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.0521 0.34 0.3474
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0521 0.34 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0014 0.0014
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger)/EF-hand domain pair, putative 0.0027 0.0056 0.0165
Echinococcus granulosus serotonin transporter 0.0307 0.1955 0.1955
Loa Loa (eye worm) hypothetical protein 0.0027 0.0056 0.0057
Schistosoma mansoni hypothetical protein 0.0027 0.0057 0.0057
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0034 0.0106 0.0615
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0111 0.0625 0.0625
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0079 0.041 0.0419
Giardia lamblia Hypothetical protein 0.0027 0.0056 0.2268
Loa Loa (eye worm) hypothetical protein 0.0027 0.0056 0.0057
Trichomonas vaginalis ubiquitin-protein ligase BRE1, putative 0.0027 0.0056 0.0032
Onchocerca volvulus 0.0027 0.0056 0.0055
Mycobacterium ulcerans polyketide synthase Pks13 0.011 0.0617 1
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0014 0.0015
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0073 0.0372 0.6023
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0027 0.0056 0.0032
Trypanosoma cruzi Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0024 0.0041 0.0017
Giardia lamblia Hypothetical protein 0.0027 0.0056 0.2268
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0068 0.0339 0.2368
Loa Loa (eye worm) hypothetical protein 0.0521 0.34 0.3475
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0521 0.34 1
Giardia lamblia Protein 21.1 0.0027 0.0056 0.2268
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0002 0.0002
Echinococcus granulosus E3 ubiquitin protein ligase Bre1 0.0027 0.0056 0.0056
Echinococcus multilocularis serotonin transporter 0.0307 0.1955 0.1955
Toxoplasma gondii SWI2/SNF2-containing protein RAD5 0.0027 0.0056 0.0057
Trichomonas vaginalis D-aminoacylase, putative 0.0034 0.0106 0.0084
Schistosoma mansoni hypothetical protein 0.0272 0.1719 0.1719
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0056 0.0032
Schistosoma mansoni hypothetical protein 0.1464 0.9785 0.9785
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.1464 0.9785 1
Leishmania major hypothetical protein, conserved 0.0521 0.34 1
Loa Loa (eye worm) hypothetical protein 0.0588 0.3858 0.3943
Leishmania major hypothetical protein, conserved 0.0022 0.0025 0.0073
Trichomonas vaginalis cell cycle control protein cwf24, putative 0.0027 0.0057 0.0032
Onchocerca volvulus Deterin homolog 0.0036 0.0121 0.0122
Mycobacterium tuberculosis Probable polyketide synthase Pks15 0.003 0.0076 0.0386
Schistosoma mansoni hypothetical protein 0.0341 0.2186 0.2186
Mycobacterium tuberculosis Probable polyketide synthase Pks9 0.0042 0.0157 0.1
Loa Loa (eye worm) hypothetical protein 0.0145 0.0859 0.0877
Brugia malayi AMP-binding enzyme family protein 0.0068 0.0339 0.0346
Brugia malayi hypothetical protein 0.0027 0.0056 0.0057
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0052 0.0229 0.0229
Echinococcus multilocularis neuropeptide s receptor 0.0439 0.2845 0.2845
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0079 0.041 0.041
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0133 0.0778 0.0778
Echinococcus multilocularis geminin 0.0341 0.2186 0.2186
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0272 0.1719 0.1757
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0188 0.0188
Echinococcus granulosus cpg binding protein 0.0061 0.0292 0.0292
Trichomonas vaginalis hypothetical protein 0.0027 0.0056 0.0032
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0034 0.0106 0.1725
Brugia malayi Doublecortin family protein 0.0019 0.0002 0.0002
Schistosoma mansoni zinc finger protein 0.0027 0.0056 0.0056
Trichomonas vaginalis sex-determining protein fem-1, putative 0.0027 0.0056 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0056 0.0032
Leishmania major hypothetical protein, conserved 0.0027 0.0056 0.0165
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0071 0.0356 0.2499
Echinococcus multilocularis tumor protein p63 0.1411 0.9425 0.9425
Entamoeba histolytica hypothetical protein 0.0111 0.0625 1
Echinococcus multilocularis chromobox protein 1 0.0069 0.0342 0.0342
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.0078 0.0402 0.6337
Echinococcus granulosus RING finger protein 185 0.0027 0.0056 0.0056
Giardia lamblia Ser/Thr protein kinase 0.0027 0.0056 0.2268
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0014 0.0015
Giardia lamblia Kinase, NEK 0.0027 0.0056 0.2268
Schistosoma mansoni inhibitor of apoptosis 1 diap1 0.0027 0.0056 0.0056
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Echinococcus multilocularis RUN 0.0019 0.0002 0.0002
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0521 0.34 1
Schistosoma mansoni hypothetical protein 0.0521 0.34 0.34
Leishmania major hypothetical protein, conserved 0.0027 0.0056 0.0165
Leishmania major hypothetical protein, conserved 0.0027 0.0056 0.0165
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0521 0.34 0.3475
Loa Loa (eye worm) hypothetical protein 0.0272 0.1719 0.1757
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Onchocerca volvulus 0.0036 0.0121 0.0122
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0048 0.0204 0.2941
Giardia lamblia Hypothetical protein 0.0027 0.0056 0.2268
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.0053 0.0232 0.156
Brugia malayi TAR-binding protein 0.0065 0.0313 0.032
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0106 0.0109
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0052 0.0229 0.0229
Schistosoma mansoni Smad4 0.0033 0.0101 0.0101
Giardia lamblia Protein 21.1 0.0027 0.0056 0.2268
Brugia malayi ecdysteroid receptor 0.0021 0.0014 0.0015
Echinococcus granulosus Smad4 0.0033 0.0101 0.0101
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.0078 0.0402 0.6522
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0157 0.0158
Onchocerca volvulus 0.0027 0.0056 0.0055
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0056 0.0165
Loa Loa (eye worm) hypothetical protein 0.0052 0.0229 0.0234
Mycobacterium ulcerans polyketide synthase Pks9 0.0048 0.0204 0.3299
Schistosoma mansoni hypothetical protein 0.1464 0.9785 0.9785
Loa Loa (eye worm) hypothetical protein 0.0039 0.0137 0.014
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Brugia malayi SWIB/MDM2 domain containing protein 0.1464 0.9785 1
Brugia malayi brahma associated protein 60 kDa 0.1464 0.9785 1
Mycobacterium tuberculosis Probable lipase LipE 0.0034 0.0106 0.0615
Mycobacterium tuberculosis Probable hydrolase 0.0034 0.0106 0.0615
Echinococcus multilocularis SWI:SNF matrix associated 0.1464 0.9785 0.9785
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.1464 0.9785 1
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0052 0.0229 0.0234
Leishmania major hypothetical protein, conserved 0.0521 0.34 1
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0052 0.0229 0.0234
Plasmodium vivax E3 ubiquitin-protein ligase RNF5, putative 0.0027 0.0056 0.0057
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0188 0.0192
Loa Loa (eye worm) hypothetical protein 0.0021 0.0014 0.0015
Giardia lamblia Protein 21.1 0.0027 0.0056 0.2268
Leishmania major hypothetical protein, conserved 0.0027 0.0056 0.0165
Giardia lamblia Protein 21.1 0.0027 0.0056 0.2268
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0139 0.0816 0.0834
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0079 0.041 0.6641
Loa Loa (eye worm) hypothetical protein 0.0521 0.34 0.3475
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0002 0.0002
Giardia lamblia Protein 21.1 0.0027 0.0056 0.2268
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0014 0.0014
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0014 0.0014
Echinococcus granulosus histone acetyltransferase KAT2B 0.0153 0.0909 0.0909
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.0078 0.0402 0.2846
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Schistosoma mansoni sodium-dependent amino acid transporter 0.0052 0.0229 0.0229
Echinococcus granulosus geminin 0.0341 0.2186 0.2186
Schistosoma mansoni peptidase Clp (S14 family) 0.0079 0.041 0.041
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.1464 0.9785 0.9785
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0188 0.0192
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0137 0.0115
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Trypanosoma cruzi Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Echinococcus granulosus dnaJ subfamily B 0.0828 0.5481 0.5481
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0056 0.0032
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Trypanosoma brucei Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0027 0.0056 0.0165
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0014 0.0014
Loa Loa (eye worm) fatty acid synthase 0.0072 0.0365 0.0373
Trypanosoma cruzi hypothetical protein, conserved 0.0521 0.34 1
Schistosoma mansoni hypothetical protein 0.0019 0.0002 0.0002
Onchocerca volvulus RING finger protein 141 homolog 0.0027 0.0056 0.0055
Loa Loa (eye worm) hypothetical protein 0.0027 0.0056 0.0057
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0861 0.5702 0.5827
Schistosoma mansoni cpg binding protein 0.0058 0.0269 0.0269
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0521 0.34 1
Brugia malayi beta-lactamase family protein 0.0034 0.0106 0.0109
Onchocerca volvulus 0.0068 0.0339 0.0344
Schistosoma mansoni peter pan-related 0.0027 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0027 0.0056 0.0057

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.