Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | unspecified product | 0.0338 | 0.1872 | 0.319 |
Onchocerca volvulus | Cathepsin L homolog | 0.0631 | 0.5637 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0338 | 0.1872 | 0.1783 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0631 | 0.5637 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0631 | 0.5637 | 1 |
Leishmania major | cathepsin L-like protease | 0.0631 | 0.5637 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0631 | 0.5637 | 0.4632 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0431 | 0.307 | 0.2994 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0631 | 0.5637 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0971 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0631 | 0.5637 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0971 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0631 | 0.5637 | 0.5589 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0395 | 0.2612 | 0.2532 |
Loa Loa (eye worm) | cysteine protease | 0.0631 | 0.5637 | 0.5589 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0631 | 0.5637 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0631 | 0.5637 | 0.5589 |
Leishmania major | cysteine peptidase A (CPA) | 0.0631 | 0.5637 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0395 | 0.2612 | 0.2532 |
Plasmodium vivax | vivapain-1 | 0.0338 | 0.1872 | 0.319 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0277 | 0.1097 | 0.1947 |
Echinococcus granulosus | cathepsin l1 | 0.0631 | 0.5637 | 0.4632 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0631 | 0.5637 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0631 | 0.5637 | 0.4632 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0631 | 0.5637 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0631 | 0.5637 | 0.5589 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0338 | 0.1872 | 0.332 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0631 | 0.5637 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0631 | 0.5637 | 0.5589 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0338 | 0.1872 | 0.1783 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0631 | 0.5637 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0631 | 0.5637 | 0.5589 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0631 | 0.5637 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0631 | 0.5637 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0631 | 0.5637 | 0.4632 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0338 | 0.1872 | 0.1783 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0631 | 0.5637 | 1 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0277 | 0.1097 | 0.1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0631 | 0.5637 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0631 | 0.5637 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.0631 | 0.5637 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0631 | 0.5637 | 0.4632 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0631 | 0.5637 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0277 | 0.1097 | 0.1947 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0631 | 0.5637 | 0.4632 |
Onchocerca volvulus | 0.0631 | 0.5637 | 1 | |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0631 | 0.5637 | 0.4632 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0277 | 0.1097 | 0.1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0431 | 0.307 | 0.5446 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0971 | 1 | 1 |
Plasmodium vivax | vivapain-2 | 0.0631 | 0.5637 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0631 | 0.5637 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0631 | 0.5637 | 0.4632 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0631 | 0.5637 | 1 |
Plasmodium vivax | vivapain-3 | 0.0338 | 0.1872 | 0.319 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0631 | 0.5637 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0631 | 0.5637 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0631 | 0.5637 | 1 |
Onchocerca volvulus | 0.0631 | 0.5637 | 1 | |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0631 | 0.5637 | 0.5589 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0338 | 0.1872 | 0.1783 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0338 | 0.1872 | 0.1783 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0631 | 0.5637 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0631 | 0.5637 | 0.5589 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0971 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.0971 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0631 | 0.5637 | 0.5589 |
Loa Loa (eye worm) | ctsf protein | 0.0631 | 0.5637 | 0.5589 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0395 | 0.2612 | 0.4635 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0631 | 0.5637 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0631 | 0.5637 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0277 | 0.1097 | 0.1947 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0971 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0338 | 0.1872 | 0.332 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0631 | 0.5637 | 0.5589 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0631 | 0.5637 | 1 |
Echinococcus granulosus | cathepsin b | 0.0971 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0631 | 0.5637 | 0.5589 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0631 | 0.5637 | 0.5589 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0631 | 0.5637 | 1 |
Leishmania major | cathepsin L-like protease | 0.0631 | 0.5637 | 1 |
Leishmania major | cathepsin L-like protease | 0.0631 | 0.5637 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0631 | 0.5637 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0431 | 0.307 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0631 | 0.5637 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0395 | 0.2612 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0277 | 0.1097 | 0.1947 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0631 | 0.5637 | 0.5589 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0631 | 0.5637 | 0.4632 |
Brugia malayi | cathepsin L-like precursor | 0.0431 | 0.307 | 0.2994 |
Onchocerca volvulus | 0.0631 | 0.5637 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0631 | 0.5637 | 1 |
Onchocerca volvulus | 0.0631 | 0.5637 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0631 | 0.5637 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0631 | 0.5637 | 0.5589 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0338 | 0.1872 | 0.1783 |
Onchocerca volvulus | Cathepsin L homolog | 0.0631 | 0.5637 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0395 | 0.2612 | 0.5 |
Onchocerca volvulus | 0.0631 | 0.5637 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0431 | 0.307 | 0.2994 |
Onchocerca volvulus | 0.0631 | 0.5637 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0631 | 0.5637 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0971 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0971 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0631 | 0.5637 | 1 |
Leishmania major | cathepsin L-like protease | 0.0631 | 0.5637 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0395 | 0.2612 | 0.1967 |
Loa Loa (eye worm) | hypothetical protein | 0.0431 | 0.307 | 0.2994 |
Plasmodium vivax | vivapain-2 | 0.0631 | 0.5637 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0631 | 0.5637 | 0.5589 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0277 | 0.1097 | 0.1947 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0631 | 0.5637 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0631 | 0.5637 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0431 | 0.307 | 0.1474 |
Loa Loa (eye worm) | cathepsin B | 0.0395 | 0.2612 | 0.2532 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0431 | 0.307 | 0.2994 |
Trypanosoma cruzi | cysteine protease, putative | 0.0338 | 0.1872 | 0.1783 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0631 | 0.5637 | 1 |
Leishmania major | cathepsin L-like protease | 0.0631 | 0.5637 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0431 | 0.307 | 0.2994 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0631 | 0.5637 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0338 | 0.1872 | 0.1783 |
Loa Loa (eye worm) | hypothetical protein | 0.0431 | 0.307 | 0.2994 |
Leishmania major | cathepsin L-like protease | 0.0631 | 0.5637 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0338 | 0.1872 | 0.1783 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0338 | 0.1872 | 0.1783 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0631 | 0.5637 | 0.5589 |
Loa Loa (eye worm) | hypothetical protein | 0.0431 | 0.307 | 0.2994 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0631 | 0.5637 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0631 | 0.5637 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0631 | 0.5637 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0631 | 0.5637 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0631 | 0.5637 | 0.5589 |
Leishmania major | cathepsin L-like protease | 0.0631 | 0.5637 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0631 | 0.5637 | 0.5589 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0431 | 0.307 | 0.5446 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0277 | 0.1097 | 0.1947 |
Onchocerca volvulus | 0.0631 | 0.5637 | 1 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0971 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0631 | 0.5637 | 1 |
Leishmania major | cathepsin L-like protease | 0.0631 | 0.5637 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0395 | 0.2612 | 0.5 |
Loa Loa (eye worm) | fibroinase | 0.0631 | 0.5637 | 0.5589 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0631 | 0.5637 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0431 | 0.307 | 0.2994 |
Entamoeba histolytica | cysteine protease, putative | 0.0631 | 0.5637 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0631 | 0.5637 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.