Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0614 | 0.1245 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0193 | 0.0221 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.0614 | 0.0486 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0193 | 0.0221 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0614 | 0.1176 |
Schistosoma mansoni | aldo-keto reductase | 0.0031 | 0.0193 | 0.0144 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0031 | 0.0193 | 0.0312 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0193 | 0.0312 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0193 | 0.0144 |
Onchocerca volvulus | 0.0031 | 0.0193 | 0.0097 | |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0193 | 0.0221 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0193 | 0.0312 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0205 | 0.5352 | 0.5289 |
Echinococcus multilocularis | aldo keto reductase | 0.0031 | 0.0193 | 0.0144 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0193 | 0.0221 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0193 | 0.0144 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0193 | 0.0312 |
Onchocerca volvulus | 0.0031 | 0.0193 | 0.0097 | |
Giardia lamblia | Aldose reductase | 0.0031 | 0.0193 | 0.5 |
Mycobacterium ulcerans | penicillin-binding protein PbpA | 0.0145 | 0.3574 | 0.6348 |
Mycobacterium tuberculosis | Probable penicillin-binding protein PbpA | 0.0145 | 0.3574 | 0.6348 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0031 | 0.0193 | 0.0312 |
Mycobacterium ulcerans | oxidoreductase | 0.0031 | 0.0193 | 0.0343 |
Trichomonas vaginalis | set domain proteins, putative | 0.0233 | 0.6194 | 1 |
Brugia malayi | Pre-SET motif family protein | 0.0205 | 0.5352 | 0.5289 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0193 | 0.0144 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0193 | 0.0312 |
Echinococcus granulosus | hypothetical protein | 0.0031 | 0.0193 | 0.0221 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0193 | 0.0221 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0031 | 0.0193 | 0.006 |
Mycobacterium tuberculosis | Possible penicillin-binding lipoprotein | 0.0214 | 0.563 | 1 |
Echinococcus multilocularis | geminin | 0.0167 | 0.4214 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0031 | 0.0193 | 0.0221 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0193 | 0.0312 |
Onchocerca volvulus | 0.0031 | 0.0193 | 0.0097 | |
Loa Loa (eye worm) | oxidoreductase | 0.0031 | 0.0193 | 0.006 |
Schistosoma mansoni | hypothetical protein | 0.0167 | 0.4214 | 1 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0031 | 0.0193 | 0.0343 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0193 | 0.0312 |
Echinococcus granulosus | aldo keto reductase | 0.0031 | 0.0193 | 0.0221 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0031 | 0.0193 | 0.0312 |
Loa Loa (eye worm) | oxidoreductase | 0.0031 | 0.0193 | 0.006 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0031 | 0.0193 | 0.0312 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.0361 | 1 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.0614 | 0.0486 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0193 | 0.0144 |
Onchocerca volvulus | 0.0233 | 0.6194 | 1 | |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0193 | 0.0221 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0193 | 0.0312 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0193 | 0.0221 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0031 | 0.0193 | 0.0312 |
Schistosoma mansoni | pol-related | 0.0031 | 0.0193 | 0.0144 |
Brugia malayi | follicle stimulating hormone receptor | 0.0228 | 0.604 | 0.5986 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0614 | 0.1176 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0031 | 0.0193 | 0.0343 |
Mycobacterium tuberculosis | Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) | 0.0163 | 0.4097 | 0.7278 |
Onchocerca volvulus | 0.0031 | 0.0193 | 0.0097 | |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.0361 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0193 | 0.0144 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0193 | 0.006 |
Mycobacterium ulcerans | penicillin-binding lipoprotein | 0.0214 | 0.563 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0031 | 0.0193 | 0.0144 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0031 | 0.0193 | 0.0312 |
Echinococcus granulosus | aldo keto reductase | 0.0031 | 0.0193 | 0.0221 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0193 | 0.0144 |
Onchocerca volvulus | 0.0031 | 0.0193 | 0.0097 | |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0614 | 0.1176 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0193 | 0.0144 |
Loa Loa (eye worm) | hypothetical protein | 0.0185 | 0.475 | 0.4678 |
Mycobacterium leprae | Probable penicillin-binding protein PbpA | 0.0145 | 0.3574 | 0.6348 |
Toxoplasma gondii | aldose reductase, putative | 0.0031 | 0.0193 | 1 |
Treponema pallidum | penicillin-binding protein (pbp-3) | 0.0097 | 0.2144 | 0.375 |
Echinococcus granulosus | geminin | 0.0167 | 0.4214 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0193 | 0.0144 |
Onchocerca volvulus | 0.0031 | 0.0193 | 0.0097 | |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0193 | 0.0221 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0031 | 0.0193 | 0.006 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0031 | 0.0193 | 0.006 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0193 | 0.0312 |
Echinococcus multilocularis | aldo keto reductase | 0.0031 | 0.0193 | 0.0144 |
Giardia lamblia | Aldose reductase | 0.0031 | 0.0193 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0031 | 0.0193 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0031 | 0.0193 | 0.006 |
Leishmania major | C-8 sterol isomerase-like protein | 0.0361 | 1 | 1 |
Schistosoma mansoni | aldo-keto reductase | 0.0031 | 0.0193 | 0.0144 |
Entamoeba histolytica | aldose reductase, putative | 0.0031 | 0.0193 | 0.5 |
Plasmodium vivax | SET domain protein, putative | 0.0029 | 0.0134 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0193 | 0.0144 |
Entamoeba histolytica | aldose reductase, putative | 0.0031 | 0.0193 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0031 | 0.0193 | 0.0221 |
Wolbachia endosymbiont of Brugia malayi | cell division protein FtsI | 0.0217 | 0.5718 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0167 | 0.4214 | 1 |
Treponema pallidum | penicillin-binding protein (pbp-1) | 0.0217 | 0.5718 | 1 |
Chlamydia trachomatis | transglycolase/transpeptidase | 0.0217 | 0.5718 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0031 | 0.0193 | 0.006 |
Mycobacterium ulcerans | penicillin-binding membrane protein PbpB | 0.0097 | 0.2144 | 0.3809 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.0614 | 0.1176 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0193 | 0.0312 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0029 | 0.0134 | 0.0078 |
Loa Loa (eye worm) | oxidoreductase | 0.0031 | 0.0193 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.0361 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0193 | 0.0144 |
Echinococcus multilocularis | aldo keto reductase | 0.0031 | 0.0193 | 0.0144 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.0614 | 0.1176 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0193 | 0.0312 |
Mycobacterium leprae | POSSIBLE PENICILLIN-BINDING LIPOPROTEIN | 0.0214 | 0.563 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.0614 | 0.1245 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0193 | 0.0312 |
Loa Loa (eye worm) | oxidoreductase | 0.0031 | 0.0193 | 0.006 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0031 | 0.0193 | 0.0144 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0228 | 0.604 | 0.5986 |
Mycobacterium ulcerans | epoxide hydrolase EphA | 0.0163 | 0.4097 | 0.7278 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0031 | 0.0193 | 0.0312 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.