Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | jmjC domain containing protein | 0.01 | 0.0991 | 0.0927 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.005 | 0.0342 | 0.064 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0143 | 0.1558 | 0.3515 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.005 | 0.0342 | 0.0342 |
Entamoeba histolytica | Sir2 family transcriptional regulator, putative | 0.0355 | 0.4302 | 0.4302 |
Toxoplasma gondii | histone deacetylase SIR2-like | 0.0215 | 0.2486 | 0.5709 |
Brugia malayi | RNA, U transporter 1 | 0.0082 | 0.0761 | 0.0695 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0038 | 0.0194 | 0.0124 |
Echinococcus multilocularis | peregrin | 0.003 | 0.0092 | 0.0021 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0038 | 0.0194 | 0.0124 |
Plasmodium falciparum | phd finger protein, putative | 0.003 | 0.0092 | 0.005 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0327 | 0.3943 | 0.8837 |
Entamoeba histolytica | NAD-dependent deacetylase 1, putative | 0.0215 | 0.2486 | 0.2486 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0194 | 0.0124 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0327 | 0.3943 | 0.8837 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0194 | 0.0124 |
Echinococcus granulosus | snurportin 1 | 0.0308 | 0.3691 | 0.3646 |
Mycobacterium tuberculosis | Probable reductase | 0.0327 | 0.3943 | 0.8837 |
Echinococcus granulosus | chromatin regulatory protein sir2 | 0.0794 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0326 | 0.392 | 0.3877 |
Trichomonas vaginalis | Citrate lyase beta chain, putative | 0.0075 | 0.0671 | 0.0671 |
Giardia lamblia | Transcriptional regulator, Sir2 family | 0.0355 | 0.4302 | 0.4249 |
Loa Loa (eye worm) | RNA binding protein | 0.0064 | 0.0522 | 0.0455 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.005 | 0.0342 | 0.0342 |
Echinococcus multilocularis | regulator of G protein signaling | 0.0038 | 0.0194 | 0.0124 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0364 | 0.4416 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0194 | 0.0124 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0028 | 0.0061 | 0.0061 |
Loa Loa (eye worm) | glutathione reductase | 0.0143 | 0.1558 | 0.1498 |
Toxoplasma gondii | thioredoxin reductase | 0.0143 | 0.1558 | 0.3515 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0211 | 0.0211 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.005 | 0.0342 | 0.0273 |
Brugia malayi | Bromodomain containing protein | 0.003 | 0.0092 | 0.0021 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0052 | 0.0373 | 0.0304 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0289 | 0.3452 | 0.3406 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.005 | 0.0342 | 0.0342 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.005 | 0.0342 | 0.0342 |
Brugia malayi | glutathione reductase | 0.0143 | 0.1558 | 0.1498 |
Brugia malayi | A-kinase anchor protein 10, precursor | 0.0038 | 0.0194 | 0.0124 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.003 | 0.0092 | 0.005 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0289 | 0.3452 | 0.3452 |
Echinococcus multilocularis | snurportin 1 | 0.0308 | 0.3691 | 0.3646 |
Echinococcus multilocularis | Regulator of G protein signaling 20 | 0.0038 | 0.0194 | 0.0124 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.029 | 0.0221 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0071 | 0.0614 | 0.0547 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0037 | 0.0175 | 0.0105 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0037 | 0.0175 | 0.0105 |
Echinococcus granulosus | expressed protein | 0.0746 | 0.9378 | 0.9373 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0143 | 0.1558 | 0.1498 |
Leishmania major | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0075 | 0.0671 | 0.0671 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0541 | 0.671 | 0.671 |
Brugia malayi | PXA domain containing protein | 0.0038 | 0.0194 | 0.0124 |
Loa Loa (eye worm) | PXA domain-containing protein | 0.0038 | 0.0194 | 0.0124 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.01 | 0.0029 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.005 | 0.0342 | 0.0342 |
Loa Loa (eye worm) | AGC/GRK/BARK protein kinase | 0.0039 | 0.0206 | 0.0136 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.005 | 0.0342 | 0.5 |
Echinococcus granulosus | tar DNA binding protein | 0.0064 | 0.0522 | 0.0455 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0038 | 0.0194 | 0.0124 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0794 | 1 | 1 |
Trypanosoma brucei | trypanothione reductase | 0.0143 | 0.1558 | 0.1498 |
Loa Loa (eye worm) | sirtuin 4 | 0.0215 | 0.2486 | 0.2433 |
Echinococcus multilocularis | NAD dependent deacetylase sirtuin 1 | 0.0541 | 0.671 | 0.6687 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0327 | 0.3943 | 0.8837 |
Brugia malayi | jmjC domain containing protein | 0.0037 | 0.0175 | 0.0105 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0039 | 0.0206 | 0.0136 |
Leishmania major | sir2-family protein-like protein | 0.0215 | 0.2486 | 0.2486 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.004 | 0.0211 | 0.0354 |
Schistosoma mansoni | chromatin regulatory protein sir2 | 0.0794 | 1 | 1 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.005 | 0.0342 | 0.0342 |
Echinococcus granulosus | NAD dependent deacetylase sirtuin 1 | 0.0541 | 0.671 | 0.6687 |
Schistosoma mansoni | regulator of G protein signaling | 0.0038 | 0.0194 | 0.0124 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0289 | 0.3452 | 0.3452 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0541 | 0.671 | 0.671 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0143 | 0.1558 | 0.1558 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0652 | 0.8155 | 0.8142 |
Mycobacterium ulcerans | hypothetical protein | 0.0075 | 0.0671 | 0.0502 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0143 | 0.1556 | 0.1556 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.003 | 0.0092 | 0.0021 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0143 | 0.1556 | 0.1556 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0037 | 0.0175 | 0.0105 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.01 | 0.0991 | 0.0927 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0194 | 0.0194 |
Trichomonas vaginalis | chromobox protein, putative | 0.0043 | 0.025 | 0.025 |
Leishmania major | NAD dependent deacetylase, putative,transcriptional regulator, Sir2 family protein, nicotinic acid mononucleotide 5,6-dimethylbe | 0.0355 | 0.4302 | 0.4302 |
Trichomonas vaginalis | mercuric reductase, putative | 0.005 | 0.0342 | 0.0342 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.029 | 0.0221 |
Trypanosoma cruzi | Silent information regulator 2 related protein 3 | 0.0355 | 0.4302 | 0.4302 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.005 | 0.0342 | 0.064 |
Loa Loa (eye worm) | transcriptional regulator | 0.0215 | 0.2486 | 0.2433 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0194 | 0.0124 |
Schistosoma mansoni | jumonji domain containing protein | 0.0079 | 0.0725 | 0.0659 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.029 | 0.0221 |
Brugia malayi | RNA binding protein | 0.0064 | 0.0522 | 0.0455 |
Mycobacterium ulcerans | citrate (pro-3S)-lyase subunit beta | 0.0075 | 0.0671 | 0.0502 |
Brugia malayi | Probable G protein-coupled receptor kinase F19C6.1, putative | 0.0039 | 0.0206 | 0.0136 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0038 | 0.0194 | 0.0124 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.005 | 0.0342 | 0.0252 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.005 | 0.0342 | 0.0342 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0194 | 0.0194 |
Trypanosoma brucei | polo-like protein kinase | 0.0289 | 0.3452 | 0.3406 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.005 | 0.0342 | 0.064 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0364 | 0.4416 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0039 | 0.0206 | 0.0136 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.005 | 0.0342 | 0.064 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0522 | 0.0455 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0289 | 0.3452 | 0.3406 |
Mycobacterium ulcerans | Sir2-like regulatory protein | 0.0215 | 0.2486 | 0.3273 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0289 | 0.3452 | 0.3452 |
Loa Loa (eye worm) | PHD-finger family protein | 0.003 | 0.0092 | 0.0021 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0289 | 0.3452 | 0.3406 |
Echinococcus multilocularis | NAD dependent deacetylase sirtuin 7 | 0.0215 | 0.2486 | 0.2433 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0194 | 0.0194 |
Echinococcus multilocularis | chromobox protein 1 | 0.0071 | 0.0614 | 0.0547 |
Brugia malayi | hypothetical protein | 0.0038 | 0.0194 | 0.0124 |
Echinococcus multilocularis | chromatin regulatory protein sir2 | 0.0794 | 1 | 1 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0289 | 0.3452 | 0.3406 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0038 | 0.0194 | 0.0124 |
Echinococcus granulosus | Regulator of G protein signaling 20 | 0.0038 | 0.0194 | 0.0124 |
Onchocerca volvulus | 0.0031 | 0.01 | 0.0023 | |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0364 | 0.4416 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0289 | 0.3452 | 0.3452 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0327 | 0.3943 | 0.8369 |
Trichomonas vaginalis | chromobox protein, putative | 0.0043 | 0.025 | 0.025 |
Mycobacterium ulcerans | citrate lyase beta subunit, CitE_2 | 0.0075 | 0.0671 | 0.0502 |
Echinococcus granulosus | chromobox protein 1 | 0.0071 | 0.0614 | 0.0547 |
Schistosoma mansoni | axis inhibition protein axin | 0.0038 | 0.0194 | 0.0124 |
Treponema pallidum | NADH oxidase | 0.005 | 0.0342 | 0.5 |
Trypanosoma cruzi | Silent information regulator 2 related protein 1 | 0.0794 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0028 | 0.0061 | 0.0061 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0541 | 0.671 | 0.671 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.003 | 0.0092 | 0.005 |
Echinococcus multilocularis | NAD dependent deacetylase sirtuin 6 | 0.0215 | 0.2486 | 0.2433 |
Brugia malayi | Heterochromatin protein 1 | 0.0071 | 0.0614 | 0.0547 |
Mycobacterium ulcerans | glutaminase | 0.0555 | 0.6895 | 1 |
Brugia malayi | regulator of G-protein signaling rgs-7 | 0.0038 | 0.0194 | 0.0124 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0037 | 0.017 | 0.01 |
Loa Loa (eye worm) | glutaminase 2 | 0.0555 | 0.6895 | 0.6873 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.01 | 0.0991 | 0.0927 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0042 | 0.0247 | 0.0177 |
Echinococcus granulosus | NAD dependent deacetylase sirtuin 7 | 0.0215 | 0.2486 | 0.2433 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0046 | 0.029 | 0.0221 |
Echinococcus granulosus | axis inhibition protein axin | 0.0038 | 0.0194 | 0.0124 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0038 | 0.0194 | 0.0124 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.005 | 0.0342 | 0.0273 |
Giardia lamblia | Kinase, PLK | 0.0289 | 0.3452 | 0.3392 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0355 | 0.4302 | 0.4302 |
Mycobacterium ulcerans | citrate (pro-3S)-lyase subunit beta | 0.0075 | 0.0671 | 0.0502 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.005 | 0.0342 | 0.0342 |
Trichomonas vaginalis | glutathione reductase, putative | 0.005 | 0.0342 | 0.0342 |
Mycobacterium ulcerans | NAD-dependent deacetylase | 0.0355 | 0.4302 | 0.6043 |
Giardia lamblia | Hypothetical protein | 0.0794 | 1 | 1 |
Brugia malayi | glutaminase DH11.1 | 0.0555 | 0.6895 | 0.6873 |
Plasmodium vivax | hypothetical protein, conserved | 0.0215 | 0.2486 | 0.5709 |
Plasmodium vivax | glutathione reductase, putative | 0.0143 | 0.1558 | 0.3515 |
Loa Loa (eye worm) | glutaminase | 0.0555 | 0.6895 | 0.6873 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0522 | 0.0455 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0652 | 0.8155 | 0.8155 |
Leishmania major | trypanothione reductase | 0.0143 | 0.1558 | 0.1558 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0046 | 0.029 | 0.0221 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0289 | 0.3452 | 0.3452 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.005 | 0.0342 | 0.0342 |
Echinococcus multilocularis | chromobox protein 1 | 0.0071 | 0.0614 | 0.0547 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0194 | 0.0194 |
Plasmodium falciparum | thioredoxin reductase | 0.005 | 0.0342 | 0.064 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0794 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0092 | 0.0021 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.005 | 0.0342 | 0.0273 |
Brugia malayi | NAD-dependent deacetylase SIRT1 | 0.0541 | 0.671 | 0.6687 |
Brugia malayi | Thioredoxin reductase | 0.0143 | 0.1558 | 0.1498 |
Trichomonas vaginalis | glutaminase, putative | 0.0555 | 0.6895 | 0.6895 |
Plasmodium vivax | hypothetical protein, conserved | 0.003 | 0.0092 | 0.005 |
Schistosoma mansoni | chromatin regulatory protein sir2 | 0.0794 | 1 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0064 | 0.0522 | 0.0455 |
Schistosoma mansoni | hypothetical protein | 0.003 | 0.0092 | 0.0021 |
Echinococcus granulosus | axis inhibition protein axin | 0.0038 | 0.0194 | 0.0124 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.005 | 0.0342 | 0.0342 |
Echinococcus multilocularis | A kinase anchor protein 10, mitochondrial | 0.0038 | 0.0194 | 0.0124 |
Loa Loa (eye worm) | transcriptional regulator | 0.0794 | 1 | 1 |
Echinococcus granulosus | peregrin | 0.003 | 0.0092 | 0.0021 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0037 | 0.0175 | 0.0105 |
Trypanosoma brucei | Silent information regulator 2 related protein 3 | 0.0355 | 0.4302 | 0.4261 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0373 | 0.0304 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0194 | 0.0194 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0215 | 0.2486 | 0.2486 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0038 | 0.0194 | 0.0124 |
Echinococcus granulosus | NAD dependent deacetylase sirtuin 6 | 0.0215 | 0.2486 | 0.2433 |
Schistosoma mansoni | regulator of G protein signaling | 0.0038 | 0.0194 | 0.0124 |
Brugia malayi | hypothetical protein | 0.0038 | 0.0194 | 0.0124 |
Leishmania major | silent information regulator 2, putative | 0.0794 | 1 | 1 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0143 | 0.1558 | 0.2985 |
Toxoplasma gondii | histone deacetylase SIR2 | 0.0355 | 0.4302 | 1 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0308 | 0.3691 | 0.3646 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0037 | 0.0175 | 0.0105 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0046 | 0.029 | 0.0221 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0374 | 0.0306 |
Trypanosoma brucei | Silent information regulator 2 related protein 1 | 0.0794 | 1 | 1 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0038 | 0.0194 | 0.0124 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0046 | 0.029 | 0.0221 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.005 | 0.0342 | 0.0342 |
Schistosoma mansoni | axis inhibition protein axin | 0.0038 | 0.0194 | 0.0124 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0038 | 0.0194 | 0.0124 |
Giardia lamblia | NAD-dependent histone deacetylase Sir2 | 0.0541 | 0.671 | 0.668 |
Leishmania major | hypothetical protein, conserved | 0.0652 | 0.8155 | 0.8155 |
Trypanosoma cruzi | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0075 | 0.0671 | 0.0671 |
Plasmodium falciparum | glutathione reductase | 0.005 | 0.0342 | 0.064 |
Mycobacterium tuberculosis | Conserved protein | 0.0075 | 0.0671 | 0.0808 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0064 | 0.0522 | 0.0455 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0289 | 0.3452 | 0.3406 |
Schistosoma mansoni | hypothetical protein | 0.0308 | 0.3691 | 0.3646 |
Schistosoma mansoni | glutaminase | 0.0555 | 0.6895 | 0.6873 |
Schistosoma mansoni | regulator of G protein signaling | 0.0038 | 0.0194 | 0.0124 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.005 | 0.0342 | 0.0273 |
Schistosoma mansoni | chromatin regulatory protein sir2 | 0.0541 | 0.671 | 0.6687 |
Echinococcus multilocularis | citrate lyase subunit beta protein | 0.0075 | 0.0671 | 0.0604 |
Plasmodium falciparum | transcriptional regulatory protein sir2a | 0.0355 | 0.4302 | 1 |
Echinococcus granulosus | A kinase anchor protein 10 mitochondrial | 0.0038 | 0.0194 | 0.0124 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0215 | 0.2486 | 0.2486 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0063 | 0.0513 | 0.0445 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0143 | 0.1558 | 0.1498 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0522 | 0.0455 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0289 | 0.3452 | 0.3452 |
Trypanosoma cruzi | Silent information regulator 2 related protein 3 | 0.0355 | 0.4302 | 0.4302 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0652 | 0.8155 | 0.8155 |
Echinococcus granulosus | jumonji domain containing protein | 0.0042 | 0.0247 | 0.0177 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.003 | 0.0092 | 0.0021 |
Schistosoma mansoni | chromatin regulatory protein sir2 | 0.0355 | 0.4302 | 0.4261 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0038 | 0.0194 | 0.0124 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.005 | 0.0342 | 0.0342 |
Entamoeba histolytica | Sir2 family transcriptional regulator, putative | 0.0794 | 1 | 1 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0289 | 0.3452 | 1 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.0039 | 0.0206 | 0.0136 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.029 | 0.0221 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0541 | 0.671 | 0.671 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0194 | 0.0194 |
Giardia lamblia | Sirtuin type 2 | 0.0215 | 0.2486 | 0.2417 |
Echinococcus granulosus | beta-adrenergic receptor kinase | 0.0039 | 0.0206 | 0.0136 |
Brugia malayi | PXA domain containing protein | 0.0038 | 0.0194 | 0.0124 |
Trichomonas vaginalis | regulator of G protein signaling 5, rgs5, putative | 0.0038 | 0.0194 | 0.0194 |
Schistosoma mansoni | chromatin regulatory protein sir2 | 0.0215 | 0.2486 | 0.2433 |
Brugia malayi | transcriptional regulator, Sir2 family protein | 0.0215 | 0.2486 | 0.2433 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0289 | 0.3452 | 0.3452 |
Schistosoma mansoni | regulator of G protein signaling 3 rgs3 | 0.0038 | 0.0194 | 0.0124 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0522 | 0.0455 |
Plasmodium vivax | NAD-dependent deacetylase, putative | 0.0355 | 0.4302 | 1 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.005 | 0.0342 | 0.0273 |
Plasmodium falciparum | glutathione reductase | 0.0143 | 0.1558 | 0.3515 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0194 | 0.0124 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0522 | 0.0455 |
Echinococcus granulosus | NAD dependent deacetylase sirtuin 3 | 0.0794 | 1 | 1 |
Brugia malayi | chromobox protein homolog 3 | 0.004 | 0.0211 | 0.0141 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.003 | 0.0092 | 0.0021 |
Echinococcus multilocularis | beta adrenergic receptor kinase | 0.0039 | 0.0206 | 0.0136 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.005 | 0.0342 | 0.0273 |
Schistosoma mansoni | chromatin regulatory protein sir2 | 0.0794 | 1 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0052 | 0.0373 | 0.0304 |
Brugia malayi | TAR-binding protein | 0.0064 | 0.0522 | 0.0455 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0038 | 0.0194 | 0.0124 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0038 | 0.0194 | 0.0124 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0289 | 0.3452 | 0.3452 |
Schistosoma mansoni | chromobox protein | 0.0071 | 0.0614 | 0.0547 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0038 | 0.0194 | 0.0124 |
Trypanosoma brucei | SIR2-like protein 4, putative | 0.0215 | 0.2486 | 0.2433 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0194 | 0.0194 |
Loa Loa (eye worm) | hypothetical protein | 0.0541 | 0.671 | 0.6687 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0143 | 0.1558 | 0.1498 |
Echinococcus granulosus | citrate lyase subunit beta protein | 0.0075 | 0.0671 | 0.0604 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0194 | 0.0194 |
Trypanosoma cruzi | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0075 | 0.0671 | 0.0671 |
Trichomonas vaginalis | chromobox protein, putative | 0.0071 | 0.0614 | 0.0614 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.005 | 0.0342 | 0.0342 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0039 | 0.0206 | 0.0136 |
Echinococcus multilocularis | expressed protein | 0.0746 | 0.9378 | 0.9373 |
Schistosoma mansoni | regulator of G protein signaling | 0.0038 | 0.0194 | 0.0124 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0159 | 0.0089 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0038 | 0.0194 | 0.0124 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0046 | 0.029 | 0.0221 |
Plasmodium falciparum | transcriptional regulatory protein sir2b | 0.0215 | 0.2486 | 0.5709 |
Echinococcus multilocularis | tar DNA binding protein | 0.0064 | 0.0522 | 0.0455 |
Plasmodium falciparum | thioredoxin reductase | 0.0143 | 0.1558 | 0.3515 |
Mycobacterium ulcerans | hypothetical protein | 0.0075 | 0.0671 | 0.0502 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.005 | 0.0342 | 0.5 |
Mycobacterium tuberculosis | Transcriptional regulatory protein | 0.0355 | 0.4302 | 0.9718 |
Schistosoma mansoni | chromobox protein | 0.0071 | 0.0614 | 0.0547 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0355 | 0.4302 | 0.4302 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0289 | 0.3452 | 0.3452 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0038 | 0.0194 | 0.0124 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0289 | 0.3452 | 0.3452 |
Loa Loa (eye worm) | transcriptional regulator | 0.0215 | 0.2486 | 0.2433 |
Echinococcus multilocularis | NAD dependent deacetylase sirtuin 3 | 0.0794 | 1 | 1 |
Brugia malayi | transcriptional regulator, Sir2 family protein | 0.0215 | 0.2486 | 0.2433 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0215 | 0.2486 | 0.2486 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0211 | 0.0141 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.005 | 0.0342 | 0.0273 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0038 | 0.0194 | 0.0124 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0037 | 0.017 | 0.01 |
Mycobacterium tuberculosis | Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) | 0.0075 | 0.0671 | 0.0808 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0194 | 0.0124 |
Schistosoma mansoni | chromatin regulatory protein sir2 | 0.0215 | 0.2486 | 0.2433 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.0159 | 0.0089 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0364 | 0.4416 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0211 | 0.0211 |
Trypanosoma cruzi | Silent information regulator 2 related protein 1 | 0.0794 | 1 | 1 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0289 | 0.3452 | 0.3452 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.005 | 0.0342 | 0.0273 |
Entamoeba histolytica | Sir2 family transcriptional regulator, putative | 0.0794 | 1 | 1 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0327 | 0.3943 | 0.8837 |
Schistosoma mansoni | kinase | 0.0147 | 0.1605 | 0.1546 |
Loa Loa (eye worm) | RGS-3 protein | 0.0038 | 0.0194 | 0.0124 |
Brugia malayi | PHD-finger family protein | 0.003 | 0.0092 | 0.0021 |
Trichomonas vaginalis | chromatin regulatory protein sir2, putative | 0.0355 | 0.4302 | 0.4302 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.005 | 0.0342 | 0.064 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0043 | 0.025 | 0.047 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0327 | 0.3943 | 0.8837 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0052 | 0.0373 | 0.0304 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0159 | 0.0089 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.005 | 0.0342 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0194 | 0.0194 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0038 | 0.0194 | 0.0124 |
Echinococcus granulosus | chromobox protein 1 | 0.0071 | 0.0614 | 0.0547 |
Schistosoma mansoni | regulator of G protein signaling | 0.0038 | 0.0194 | 0.0124 |
Loa Loa (eye worm) | TAR-binding protein | 0.0064 | 0.0522 | 0.0455 |
Trichomonas vaginalis | chromobox protein, putative | 0.0071 | 0.0614 | 0.0614 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.005 | 0.0342 | 0.064 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.