Detailed information for compound 691054

Basic information

Technical information
  • TDR Targets ID: 691054
  • Name: N-(3-methylphenyl)-2-[1-(2-methylphenyl)-4-ox opyrazolo[5,4-d]pyrimidin-5-yl]acetamide
  • MW: 373.408 | Formula: C21H19N5O2
  • H donors: 1 H acceptors: 3 LogP: 2.82 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1cccc(c1)NC(=O)Cn1cnc2c(c1=O)cnn2c1ccccc1C
  • InChi: 1S/C21H19N5O2/c1-14-6-5-8-16(10-14)24-19(27)12-25-13-22-20-17(21(25)28)11-23-26(20)18-9-4-3-7-15(18)2/h3-11,13H,12H2,1-2H3,(H,24,27)
  • InChiKey: FCGAWYPWFPEISC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(3-methylphenyl)-2-[1-(2-methylphenyl)-4-oxo-pyrazolo[5,4-d]pyrimidin-5-yl]acetamide
  • N-(3-methylphenyl)-2-[1-(2-methylphenyl)-4-oxo-5-pyrazolo[5,4-d]pyrimidinyl]acetamide
  • 2-[4-keto-1-(2-methylphenyl)pyrazolo[5,4-d]pyrimidin-5-yl]-N-(3-methylphenyl)acetamide
  • N-(3-methylphenyl)-2-[1-(2-methylphenyl)-4-oxo-pyrazolo[5,4-d]pyrimidin-5-yl]ethanamide
  • ZINC04479011

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0037 0.0149 0.0141
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0033 0.012 0.0112
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0157 0.0915 0.0915
Mycobacterium tuberculosis Conserved hypothetical protein 0.0039 0.0162 0.0245
Onchocerca volvulus 0.0932 0.5874 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.003 0.0105 0.0097
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0157 0.0915 0.0915
Brugia malayi hypothetical protein 0.0157 0.0915 0.0912
Echinococcus granulosus lysophospholipid acyltransferase 7 0.0016 0.0016 0.0008
Onchocerca volvulus 0.0807 0.5072 0.8631
Giardia lamblia Hypothetical protein 0.0207 0.1232 0.2968
Onchocerca volvulus 0.0102 0.0564 0.0938
Entamoeba histolytica hypothetical protein 0.0207 0.1232 0.2076
Echinococcus multilocularis lysine specific demethylase 5A 0.0134 0.0768 0.0761
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0021 0.0045 0.0045
Brugia malayi Serotonin receptor 0.0157 0.0915 0.0912
Schistosoma mansoni hypothetical protein 0.0021 0.0045 0.0045
Schistosoma mansoni metabotropic glutamate receptor 0.0026 0.0079 0.0079
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0207 0.1232 0.2076
Schistosoma mansoni neuropeptide receptor 0.0157 0.0915 0.0915
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0631 0.3944 0.523
Leishmania major cytochrome p450-like protein 0.0073 0.0379 0.0503
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0064 0.0085
Echinococcus granulosus g protein coupled receptor 0.0157 0.0915 0.0908
Loa Loa (eye worm) hypothetical protein 0.0075 0.0391 0.0388
Echinococcus granulosus G protein coupled receptor 139 0.0157 0.0915 0.0908
Mycobacterium ulcerans bifunctional protein acetyl-/propionyl-coenzyme a carboxylase (alpha chain) AccA3 0.0062 0.0307 0.3647
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0162 0.0215
Plasmodium falciparum LCCL domain-containing protein 0.0016 0.0014 0.0024
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Echinococcus granulosus biogenic amine 5HT receptor 0.0157 0.0915 0.0908
Echinococcus multilocularis g protein coupled receptor 0.0157 0.0915 0.0908
Trichomonas vaginalis glucosylceramidase, putative 0.0215 0.1285 0.2167
Echinococcus multilocularis lipoxygenase domain containing protein 0.0016 0.0014 0.0006
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0109 0.0145
Brugia malayi hypothetical protein 0.0157 0.0915 0.0912
Echinococcus multilocularis dro:myosuppressin receptor 0.0157 0.0915 0.0908
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0207 0.1232 0.2098
Entamoeba histolytica cysteine protease, putative 0.0207 0.1232 0.2076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.5874 1
Brugia malayi Cathepsin L-like precursor 0.0294 0.1792 0.179
Brugia malayi Smad1 0.0025 0.0067 0.0064
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0021 0.0045 0.0539
Toxoplasma gondii acyl-CoA:cholesterol acyltransferase alpha ACAT1-alpha 0.0016 0.0016 0.0027
Loa Loa (eye worm) hhat protein 0.0016 0.0016 0.0012
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.0045 0.0045
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0021 0.0045 0.0539
Brugia malayi N-myristoyltransferase 2 0.011 0.0614 0.0611
Schistosoma mansoni ap endonuclease 0.005 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.1577 1 1
Brugia malayi MH2 domain containing protein 0.0025 0.0067 0.0064
Schistosoma mansoni polycystin 1-related 0.0016 0.0014 0.0014
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0207 0.1232 0.1232
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0207 0.1232 0.2098
Leishmania major cathepsin L-like protease 0.0932 0.5874 0.779
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0021 0.0045 0.0045
Plasmodium falciparum serine repeat antigen 9 0.0207 0.1232 0.2098
Trichomonas vaginalis D-aminoacylase, putative 0.0145 0.0841 0.1408
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0139 0.0136
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0036 0.0139 0.0237
Schistosoma mansoni Smad4 0.0025 0.0067 0.0067
Mycobacterium tuberculosis Probable propionyl-CoA carboxylase beta chain 5 AccD5 (pccase) (propanoyl-CoA:carbon dioxide ligase) 0.0022 0.0051 0.0056
Entamoeba histolytica cysteine proteinase, putative 0.0501 0.3114 0.5289
Brugia malayi Melatonin receptor type 1A 0.0157 0.0915 0.0912
Schistosoma mansoni lamin 0.0027 0.0084 0.0084
Echinococcus multilocularis GPCR, family 2 0.003 0.0105 0.0097
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0064 0.0077
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0932 0.5874 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0157 0.0915 0.0915
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0021 0.0045 0.0045
Echinococcus granulosus serotonin receptor 0.0157 0.0915 0.0908
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0162 0.0215
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0035 0.0133 0.013
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0031 0.0109 0.0186
Mycobacterium leprae Probable lipase LipE 0.0145 0.0841 1
Mycobacterium ulcerans lipase LipD 0.0145 0.0841 1
Loa Loa (eye worm) diacylglycerol acyltransferase 0.0016 0.0016 0.0012
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0064 0.0061
Toxoplasma gondii acyl-CoA carboxyltransferase beta chain, putative 0.0022 0.0051 0.0088
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0035 0.0133 0.0133
Schistosoma mansoni diacylglycerol O-acyltransferase 1 0.0016 0.0016 0.0016
Leishmania major cytochrome p450-like protein 0.0021 0.0045 0.006
Brugia malayi Pre-SET motif family protein 0.0102 0.0564 0.0561
Echinococcus granulosus glycylpeptide N tetradecanoyltransferase 0.011 0.0614 0.0607
Brugia malayi Cytochrome P450 family protein 0.0021 0.0045 0.0042
Brugia malayi Importin beta-1 subunit 0.0015 0.0008 0.0004
Onchocerca volvulus 0.0932 0.5874 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.754 1
Trypanosoma brucei hypothetical protein, conserved 0.0145 0.0841 0.1115
Toxoplasma gondii cathepsin CPC2 0.0207 0.1232 0.2098
Schistosoma mansoni amine GPCR 0.0157 0.0915 0.0915
Schistosoma mansoni rab6-interacting 0.0016 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Entamoeba histolytica cysteine protease, putative 0.0207 0.1232 0.2076
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0157 0.0915 0.0915
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0157 0.0915 0.0915
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0157 0.0915 0.0908
Loa Loa (eye worm) G-protein coupled receptor 0.0157 0.0915 0.0912
Echinococcus granulosus cathepsin b 0.1577 1 1
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0025 0.0043
Echinococcus multilocularis propionyl coenzyme A carboxylase beta chain 0.0022 0.0051 0.0044
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0139 0.0136
Entamoeba histolytica cysteine protease, putative 0.0207 0.1232 0.2076
Schistosoma mansoni cathepsin B (C01 family) 0.0207 0.1232 0.1232
Brugia malayi hypothetical protein 0.0157 0.0915 0.0912
Echinococcus multilocularis transient receptor potential cation channel 0.0166 0.0974 0.0966
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0294 0.1792 0.179
Echinococcus granulosus peptide allatostatin:somatostatin 0.0157 0.0915 0.0908
Loa Loa (eye worm) G-protein coupled receptor 0.0157 0.0915 0.0912
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0207 0.1232 0.2968
Toxoplasma gondii preprocathepsin c precursor, putative 0.0207 0.1232 0.2098
Brugia malayi neuropeptide F receptor 0.0157 0.0915 0.0912
Loa Loa (eye worm) Smad1 0.0025 0.0067 0.0064
Trichomonas vaginalis glucosylceramidase, putative 0.0215 0.1285 0.2167
Echinococcus multilocularis isocitrate dehydrogenase 0.0031 0.0109 0.0102
Brugia malayi Cytochrome P450 family protein 0.0073 0.0379 0.0376
Trichomonas vaginalis DNA polymerase eta, putative 0.0039 0.0162 0.025
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0064 0.0061
Schistosoma mansoni sterol O-acyltransferase 1 0.0169 0.0988 0.0988
Onchocerca volvulus 0.0157 0.0915 0.1538
Schistosoma mansoni smad1 5 8 and 0.0025 0.0067 0.0067
Trypanosoma brucei N-myristoyltransferase 0.011 0.0614 0.0814
Echinococcus granulosus rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Brugia malayi Papain family cysteine protease containing protein 0.0207 0.1232 0.1229
Echinococcus multilocularis dna polymerase eta 0.0039 0.0162 0.0154
Brugia malayi metabotropic glutamate receptor type 2 0.0017 0.0021 0.0018
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0157 0.0915 0.0915
Plasmodium vivax unspecified product 0.0207 0.1232 0.2098
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1577 1 1
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0932 0.5874 1
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0022 0.0051 0.0051
Echinococcus multilocularis tar DNA binding protein 0.0096 0.0524 0.0517
Loa Loa (eye worm) jmjC domain-containing protein 0.0136 0.0778 0.0775
Echinococcus multilocularis geminin 0.0555 0.346 0.3455
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0501 0.3114 0.5289
Schistosoma mansoni phd/f-box containing protein 0.0036 0.0139 0.0139
Schistosoma mansoni metabotropic glutamate receptor 0.0017 0.0021 0.0021
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0932 0.5874 1
Echinococcus multilocularis allatostatin A receptor 0.0157 0.0915 0.0908
Toxoplasma gondii exonuclease III APE 0.005 0.0231 0.0393
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0021 0.0045 0.006
Brugia malayi hypothetical protein 0.0157 0.0915 0.0912
Schistosoma mansoni transient receptor potential cation channel subfamily A member 0.0161 0.0941 0.0941
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0037 0.0149 0.0141
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0084 0.0111
Echinococcus multilocularis orexin receptor type 2 0.0157 0.0915 0.0908
Schistosoma mansoni amine GPCR 0.0157 0.0915 0.0915
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0062 0.0307 0.0307
Echinococcus multilocularis rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0016 0.0016 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0638 0.3992 0.6788
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0145 0.0841 0.1408
Brugia malayi MH2 domain containing protein 0.036 0.2214 0.2211
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0207 0.1232 0.1232
Schistosoma mansoni histamine h1 receptor 0.0157 0.0915 0.0915
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0021 0.0045 0.0045
Brugia malayi Cathepsin L-like precursor 0.0638 0.3992 0.399
Plasmodium falciparum glycylpeptide N-tetradecanoyltransferase 0.011 0.0614 0.1045
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0207 0.1232 0.2098
Echinococcus multilocularis sterol O acyltransferase 1 0.0169 0.0988 0.0981
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0932 0.5874 1
Schistosoma mansoni cpg binding protein 0.0028 0.0091 0.0091
Echinococcus granulosus cpg binding protein 0.0028 0.0091 0.0083
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0026 0.0079 0.0071
Echinococcus multilocularis g protein coupled receptor 0.0157 0.0915 0.0908
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0036 0.0144 0.0136
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0025 0.0011
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0021 0.0045 0.0045
Loa Loa (eye worm) MBOAT family protein 0.0016 0.0016 0.0012
Echinococcus granulosus snurportin 1 0.0163 0.095 0.0943
Onchocerca volvulus Glucosylceramidase homolog 0.0215 0.1285 0.2169
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0932 0.5874 1
Echinococcus multilocularis tumor protein p63 0.0678 0.4247 0.4243
Echinococcus multilocularis glutamate receptor 2 0.0033 0.012 0.0112
Echinococcus multilocularis propionyl coenzyme A carboxylase alpha chain 0.0062 0.0307 0.0299
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0207 0.1232 0.2076
Onchocerca volvulus Cathepsin F homolog 0.0932 0.5874 1
Brugia malayi cathepsin L-like precursor 0.0638 0.3992 0.399
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.005 0.0231 0.7521
Echinococcus multilocularis rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Plasmodium vivax serine-repeat antigen (SERA) 0.0207 0.1232 0.2098
Brugia malayi Papain family cysteine protease containing protein 0.0932 0.5874 0.5873
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0145 0.0841 1
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0162 0.0215
Schistosoma mansoni tar DNA-binding protein 0.0096 0.0524 0.0524
Brugia malayi Calcitonin receptor-like protein seb-1 0.0096 0.0524 0.0521
Giardia lamblia Cathepsin B precursor 0.0207 0.1232 0.2968
Brugia malayi Pre-SET motif family protein 0.0709 0.4444 0.4442
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0067 0.0064
Schistosoma mansoni methylcrotonyl-CoA carboxylase 0.0062 0.0307 0.0307
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0501 0.3114 0.3114
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0064 0.0762
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0157 0.0915 0.0915
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0207 0.1232 0.2098
Toxoplasma gondii pyruvate carboxylase 0.0062 0.0307 0.0522
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0207 0.1232 0.2098
Brugia malayi hypothetical protein 0.0157 0.0915 0.0912
Echinococcus granulosus rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Plasmodium falciparum serine repeat antigen 3 0.0207 0.1232 0.2098
Brugia malayi Dopamine receptor protein 2 0.0157 0.0915 0.0912
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0096 0.0524 0.0521
Echinococcus granulosus neuropeptide Y receptor 0.0157 0.0915 0.0908
Echinococcus granulosus orexin receptor type 2 0.0157 0.0915 0.0908
Brugia malayi G-protein coupled receptor 0.0157 0.0915 0.0912
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0084 0.0081
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0207 0.1232 0.2968
Echinococcus multilocularis neuropeptide s receptor 0.0157 0.0915 0.0908
Toxoplasma gondii acyl-CoA:diacylglycerol acyltransferase 1-related enzyme 0.0016 0.0016 0.0027
Loa Loa (eye worm) hypothetical protein 0.0024 0.0064 0.0061
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0932 0.5874 0.5871
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0021 0.0045 0.0539
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0932 0.5874 1
Schistosoma mansoni hypothetical protein 0.003 0.0105 0.0105
Brugia malayi MH2 domain containing protein 0.0025 0.0067 0.0064
Schistosoma mansoni hypothetical protein 0.0016 0.0016 0.0016
Echinococcus granulosus transcription factor Dp 1 0.002 0.0039 0.0032
Loa Loa (eye worm) hypothetical protein 0.0027 0.0081 0.0077
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0157 0.0915 0.0915
Trichomonas vaginalis set domain proteins, putative 0.0807 0.507 0.8628
Loa Loa (eye worm) hypothetical protein 0.0052 0.0244 0.0241
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0157 0.0915 0.0908
Trypanosoma cruzi hypothetical protein, conserved 0.0145 0.0841 0.0841
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0064 0.0762
Schistosoma mansoni biogenic amine receptor 0.0157 0.0915 0.0915
Onchocerca volvulus 0.0157 0.0915 0.1538
Echinococcus multilocularis dna polymerase kappa 0.0039 0.0162 0.0154
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0207 0.1232 0.2076
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0021 0.0045 0.0539
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0036 0.0139 0.0139
Entamoeba histolytica cysteine protease, putative 0.0501 0.3114 0.5289
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0021 0.0045 0.0045
Brugia malayi RE15519p 0.0157 0.0915 0.0912
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0157 0.0915 0.0912
Loa Loa (eye worm) hypothetical protein 0.0027 0.0084 0.0081
Onchocerca volvulus 0.0157 0.0915 0.1538
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0187 0.0318
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.754 1
Echinococcus granulosus neuropeptides capa receptor 0.0157 0.0915 0.0908
Brugia malayi MBOAT family protein 0.0016 0.0016 0.0012
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0207 0.1232 0.1232
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0501 0.3114 0.3114
Echinococcus multilocularis snurportin 1 0.0163 0.095 0.0943
Brugia malayi cytochrome P450 0.0021 0.0045 0.0042
Giardia lamblia Cysteine protease 0.0207 0.1232 0.2968
Loa Loa (eye worm) hypothetical protein 0.0016 0.0016 0.0012
Trypanosoma cruzi DNA polymerase eta, putative 0.0039 0.0162 0.0162
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0021 0.0045 0.0539
Echinococcus granulosus neuropeptides capa receptor 0.0157 0.0915 0.0908
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0134 0.0768 0.0761
Echinococcus granulosus RUN 0.0016 0.0014 0.0006
Echinococcus granulosus biogenic amine 5HT receptor 0.0157 0.0915 0.0908
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0932 0.5874 0.5873
Echinococcus granulosus dna polymerase kappa 0.0039 0.0162 0.0154
Onchocerca volvulus Cathepsin L homolog 0.0932 0.5874 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0207 0.1232 0.2076
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0035 0.0133 0.013
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0207 0.1232 0.1229
Schistosoma mansoni cpg binding protein 0.0027 0.0081 0.0081
Brugia malayi hypothetical protein 0.0157 0.0915 0.0912
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0207 0.1232 0.2968
Brugia malayi Cytochrome P450 family protein 0.0021 0.0045 0.0042
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0501 0.3114 0.3114
Leishmania major propionyl-coa carboxylase beta chain, putative 0.0022 0.0051 0.0068
Loa Loa (eye worm) hypothetical protein 0.0207 0.1232 0.1229
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0631 0.3944 0.3944
Trypanosoma cruzi cytochrome P450, putative 0.0073 0.0379 0.0379
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0021 0.0045 0.0045
Plasmodium falciparum cysteine proteinase falcipain 3 0.0932 0.5874 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0064 0.0085
Brugia malayi Glutamate receptor 1 precursor 0.0025 0.0073 0.007
Onchocerca volvulus 0.0099 0.0545 0.0906
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0064 0.0082
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0031 0.0109 0.0155
Trypanosoma brucei N-myristoyl transferase, putative 0.011 0.0614 0.0814
Trypanosoma cruzi cruzipain precursor, putative 0.1193 0.754 0.754
Leishmania major methylcrotonoyl-coa carboxylase biotinylated subunitprotein-like protein 0.0062 0.0307 0.0407
Mycobacterium tuberculosis Conserved protein 0.0145 0.0841 0.1408
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0207 0.1232 0.2098
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0016 0.0016 0.0008
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0102 0.0564 0.0557
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0021 0.0045 0.0539
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.754 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0157 0.0915 0.0912
Echinococcus granulosus neuropeptide Y receptor 0.0157 0.0915 0.0908
Wolbachia endosymbiont of Brugia malayi Acetyl-CoA carboxylase, carboxyltransferase component 0.0022 0.0051 0.1676
Brugia malayi Cytochrome P450 family protein 0.0073 0.0379 0.0376
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0294 0.1792 0.179
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0067 0.0064
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0064 0.0082
Echinococcus granulosus rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0932 0.5874 1
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0157 0.0915 0.0908
Loa Loa (eye worm) hypothetical protein 0.0294 0.1792 0.179
Loa Loa (eye worm) MBOAT family protein 0.0016 0.0016 0.0012
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0062 0.0307 0.0307
Mycobacterium ulcerans hypothetical protein 0.0145 0.0841 1
Entamoeba histolytica cysteine protease, putative 0.0501 0.3114 0.5289
Echinococcus granulosus tumor protein p63 0.0678 0.4247 0.4243
Echinococcus granulosus somatostatin receptor 0.0157 0.0915 0.0908
Schistosoma mansoni cathepsin F (C01 family) 0.0638 0.3992 0.3992
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0162 0.0215
Echinococcus multilocularis o acyltransferase (membrane bound) domain 0.0016 0.0016 0.0008
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0025 0.0043
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0021 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0207 0.1232 0.2098
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0039 0.0162 0.0154
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0021 0.0045 0.0045
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0157 0.0915 0.0915
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0157 0.0915 0.0915
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0035 0.0133 0.0133
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0035 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Echinococcus granulosus rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Mycobacterium tuberculosis Probable hydrolase 0.0145 0.0841 0.1408
Wolbachia endosymbiont of Brugia malayi Acetyl/propionyl-CoA carboxylase, alpha subunit 0.0062 0.0307 1
Brugia malayi Serotonin receptor 0.0157 0.0915 0.0912
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0157 0.0915 0.0915
Plasmodium vivax serine-repeat antigen (SERA) 0.0207 0.1232 0.2098
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.5874 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0157 0.0915 0.0908
Trypanosoma brucei unspecified product 0.0027 0.0084 0.0111
Loa Loa (eye worm) hypothetical protein 0.0036 0.0139 0.0136
Onchocerca volvulus 0.0016 0.0016 0.0003
Echinococcus multilocularis sex peptide receptor 0.0157 0.0915 0.0908
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0187 0.0292
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0021 0.0045 0.0539
Loa Loa (eye worm) hypothetical protein 0.0207 0.1232 0.1229
Brugia malayi cathepsin F-like cysteine proteinase 0.0294 0.1792 0.179
Schistosoma mansoni cathepsin F (C01 family) 0.0932 0.5874 0.5874
Trypanosoma brucei cytochrome P450, putative 0.0073 0.0379 0.0503
Plasmodium vivax vivapain-3 0.0501 0.3114 0.5301
Schistosoma mansoni tar DNA-binding protein 0.0096 0.0524 0.0524
Echinococcus multilocularis G-protein coupled receptor, putative 0.0157 0.0915 0.0908
Loa Loa (eye worm) hypothetical protein 0.0024 0.0064 0.0061
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0187 0.0318
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0162 0.1927
Brugia malayi jmjC domain containing protein 0.0136 0.0778 0.0775
Schistosoma mansoni ap endonuclease 0.005 0.0231 0.0231
Brugia malayi intermediate filament protein 0.0027 0.0084 0.0081
Loa Loa (eye worm) cytochrome P450 family protein 0.0021 0.0045 0.0042
Brugia malayi Papain family cysteine protease containing protein 0.0501 0.3114 0.3112
Echinococcus multilocularis somatostatin receptor 0.0157 0.0915 0.0908
Schistosoma mansoni smad1 5 8 and 0.0025 0.0067 0.0067
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.005 0.0231 0.037
Trichomonas vaginalis glucosylceramidase, putative 0.0328 0.2006 0.3397
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Trypanosoma brucei glycerol uptake protein, putative 0.0016 0.0016 0.0021
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.754 1
Plasmodium falciparum diacylglycerol O-acyltransferase 0.0016 0.0016 0.0027
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.005 0.0231 0.0231
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0016 0.0016 0.0016
Schistosoma mansoni lipoxygenase 0.0097 0.0531 0.0531
Brugia malayi neuropeptide F receptor 0.0157 0.0915 0.0912
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0064 0.0762
Loa Loa (eye worm) hypothetical protein 0.0207 0.1232 0.1229
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0064 0.0235
Echinococcus granulosus nmda type glutamate receptor 0.0057 0.0277 0.0269
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0021 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Schistosoma mansoni hypothetical protein 0.003 0.0105 0.0105
Onchocerca volvulus 0.0932 0.5874 1
Echinococcus granulosus tm gpcr rhodopsin 0.0157 0.0915 0.0908
Echinococcus granulosus neuropeptide receptor A26 0.0157 0.0915 0.0908
Loa Loa (eye worm) beta-lactamase 0.0145 0.0841 0.0838
Brugia malayi cathepsin Z-like cysteine proteinase 0.0207 0.1232 0.1229
Brugia malayi Cathepsin L-like precursor 0.0932 0.5874 0.5873
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0145 0.0841 0.0841
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1577 1 1
Schistosoma mansoni zinc finger protein 0.0016 0.0016 0.0016
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0025 0.03
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0207 0.1232 0.2076
Plasmodium falciparum serine repeat antigen 5 0.0207 0.1232 0.2098
Brugia malayi jmjC domain containing protein 0.0036 0.0139 0.0136
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0157 0.0915 0.0908
Trichomonas vaginalis N-myristoyl transferase, putative 0.011 0.0614 0.1021
Echinococcus granulosus histone lysine methyltransferase setb 0.0102 0.0564 0.0557
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Loa Loa (eye worm) hypothetical protein 0.0638 0.3992 0.399
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0157 0.0915 0.0912
Brugia malayi Cathepsin L-like precursor 0.0932 0.5874 0.5873
Echinococcus granulosus neuropeptide receptor 0.0157 0.0915 0.0908
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0157 0.0915 0.0908
Trypanosoma cruzi cysteine peptidase, putative 0.1193 0.754 0.754
Schistosoma mansoni lamin 0.0027 0.0084 0.0084
Leishmania major hypothetical protein, conserved 0.0036 0.0139 0.0185
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0035 0.0133 0.0201
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0157 0.0915 0.0908
Toxoplasma gondii acetyl-CoA carboxylase ACC1 0.0163 0.0951 0.1618
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.005 0.0231 0.2743
Onchocerca volvulus 0.0157 0.0915 0.1538
Giardia lamblia Cathepsin L-like protease 0.0207 0.1232 0.2968
Echinococcus granulosus dro:myosuppressin receptor 0.0157 0.0915 0.0908
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0207 0.1232 0.2076
Echinococcus multilocularis neuropeptides capa receptor 0.0157 0.0915 0.0908
Echinococcus granulosus cathepsin L 0.0207 0.1232 0.1225
Mycobacterium leprae Probable propionyl-CoA carboxylase beta chain 5 AccD5 (PCCASE) (PROPANOYL-COA:CARBON DIOXIDE LIGASE) 0.0022 0.0051 0.0076
Leishmania major cathepsin L-like protease 0.0932 0.5874 0.779
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0187 0.0292
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0162 0.0215
Giardia lamblia Cathepsin L precursor 0.0207 0.1232 0.2968
Entamoeba histolytica cysteine proteinase, putative 0.0932 0.5874 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0036 0.0139 0.0136
Onchocerca volvulus 0.0145 0.0841 0.1411
Giardia lamblia Cathepsin B precursor 0.0207 0.1232 0.2968
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0141 0.081 0.0807
Entamoeba histolytica cysteine proteinase, putative 0.0932 0.5874 1
Echinococcus granulosus histone acetyltransferase KAT2B 0.0143 0.0823 0.0816
Plasmodium falciparum serine repeat antigen 6 0.0207 0.1232 0.2098
Leishmania major N-myristoyl transferase, putative 0.011 0.0614 0.0814
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0207 0.1232 0.2076
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0064 0.0762
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0064 0.0762
Trypanosoma cruzi GUP1, putative 0.0016 0.0016 0.0016
Echinococcus multilocularis nmda type glutamate receptor 0.0059 0.0291 0.0283
Toxoplasma gondii ABC1 family protein 0.0145 0.0841 0.1431
Loa Loa (eye worm) hypothetical protein 0.0145 0.0841 0.0838
Loa Loa (eye worm) hypothetical protein 0.0066 0.033 0.0327
Echinococcus multilocularis RUN 0.0016 0.0014 0.0006
Trypanosoma cruzi glycerol uptake protein, putative 0.0016 0.0016 0.0016
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0207 0.1232 0.1232
Mycobacterium ulcerans beta-lactamase 0.0145 0.0841 1
Brugia malayi beta-lactamase 0.0145 0.0841 0.0838
Brugia malayi follicle stimulating hormone receptor 0.0157 0.0915 0.0912
Onchocerca volvulus Huntingtin homolog 0.0075 0.0391 0.0643
Echinococcus granulosus lipoxygenase domain containing protein 0.0016 0.0014 0.0006
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0157 0.0915 0.0908
Echinococcus multilocularis lysophospholipid acyltransferase 7 0.0016 0.0016 0.0008
Schistosoma mansoni jumonji domain containing protein 0.0134 0.0768 0.0768
Entamoeba histolytica cysteine protease, putative 0.0501 0.3114 0.5289
Loa Loa (eye worm) hypothetical protein 0.0932 0.5874 0.5873
Schistosoma mansoni cathepsin S (C01 family) 0.0207 0.1232 0.1232
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0157 0.0915 0.1538
Echinococcus multilocularis neuropeptide receptor A26 0.0157 0.0915 0.0908
Trichomonas vaginalis glucosylceramidase, putative 0.0215 0.1285 0.2167
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0157 0.0915 0.0912
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0022
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0157 0.0915 0.0912
Echinococcus granulosus cathepsin l1 0.0638 0.3992 0.3987
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0207 0.1232 0.2076
Trypanosoma brucei DNA polymerase eta, putative 0.0039 0.0162 0.0215
Trypanosoma brucei unspecified product 0.0041 0.0171 0.0227
Loa Loa (eye worm) hypothetical protein 0.003 0.0105 0.0101
Brugia malayi beta-lactamase family protein 0.0145 0.0841 0.0838
Entamoeba histolytica glycylpeptide N-tetradecanoyltransferase, putative 0.011 0.0614 0.1021
Loa Loa (eye worm) hypothetical protein 0.0024 0.0064 0.0061
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Brugia malayi fibroinase precursor 0.0207 0.1232 0.1229
Loa Loa (eye worm) cytochrome P450 family protein 0.0073 0.0379 0.0376
Echinococcus multilocularis nmda type glutamate receptor 0.0057 0.0277 0.0269
Loa Loa (eye worm) hypothetical protein 0.0145 0.0841 0.0838
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0157 0.0915 0.0912
Onchocerca volvulus 0.0157 0.0915 0.1538
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0207 0.1232 0.1229
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.005 0.0231 0.0306
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 4 AccD4_2 0.0022 0.0051 0.0611
Schistosoma mansoni terminal deoxycytidyl transferase 0.0039 0.0162 0.0162
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0157 0.0915 0.0908
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0207 0.1232 0.2098
Loa Loa (eye worm) hypothetical protein 0.0039 0.0162 0.0159
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0162 0.0162
Echinococcus granulosus beta LACTamase domain containing family member 0.0145 0.0841 0.0834
Echinococcus granulosus diacylglycerol O acyltransferase 1 0.0016 0.0016 0.0008
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Leishmania major glycerol uptake protein, putative 0.0016 0.0016 0.0021
Schistosoma mansoni importin beta-1 0.0015 0.0008 0.0008
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0031 0.0109 0.0109
Echinococcus multilocularis rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Echinococcus granulosus rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Schistosoma mansoni glutamate receptor kainate 0.0025 0.0073 0.0073
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0064 0.0077
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0207 0.1232 0.2076
Leishmania major 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0022 0.0051 0.0068
Entamoeba histolytica cysteine proteinase, putative 0.0501 0.3114 0.5289
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0031 0.0109 0.0102
Leishmania major DNA polymerase eta, putative 0.0039 0.0162 0.0215
Onchocerca volvulus 0.0024 0.0064 0.0085
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.754 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0096 0.0524 0.0521
Echinococcus granulosus cytochrome P450 2K1 0.0021 0.0045 0.0038
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0297 0.0297
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0021 0.0045 0.0045
Schistosoma mansoni hypothetical protein 0.0157 0.0915 0.0915
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0084 0.0111
Plasmodium falciparum JmjC domain-containing protein, putative 0.0036 0.0139 0.0237
Echinococcus granulosus o acyltransferase membrane bound domain 0.0016 0.0016 0.0008
Trypanosoma cruzi cysteine peptidase, putative 0.0501 0.3114 0.3114
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0157 0.0915 0.0908
Trypanosoma brucei 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0022 0.0051 0.0068
Loa Loa (eye worm) glutamate receptor 1 0.0025 0.0073 0.007
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain, AccA2 0.0062 0.0307 0.3647
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.005 0.0231 0.0223
Brugia malayi exodeoxyribonuclease III family protein 0.005 0.0231 0.0227
Loa Loa (eye worm) hypothetical protein 0.0207 0.1232 0.1229
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0207 0.1232 0.2098
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0157 0.0915 0.0908
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0021 0.0045 0.0539
Echinococcus multilocularis transcription factor Dp 1 0.002 0.0039 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0207 0.1232 0.2076
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0022
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0207 0.1232 0.2076
Toxoplasma gondii cathepsin CPC1 0.0207 0.1232 0.2098
Plasmodium falciparum serine repeat antigen 8 0.0207 0.1232 0.2098
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0021 0.0045 0.0045
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0036 0.0139 0.0185
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0501 0.3114 0.3114
Echinococcus granulosus Membrane bound O acyl transferase MBOAT 0.0016 0.0016 0.0008
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.5874 1
Mycobacterium tuberculosis Probable lipase LipD 0.0145 0.0841 0.1408
Brugia malayi Cathepsin L-like precursor 0.0932 0.5874 0.5873
Leishmania major cathepsin L-like protease 0.1193 0.754 1
Trypanosoma brucei acetyl-CoA carboxylase 0.0163 0.0951 0.1261
Brugia malayi isocitrate dehydrogenase 0.0031 0.0109 0.0106
Trypanosoma cruzi major cysteine proteinase, putative 0.0467 0.2899 0.2899
Echinococcus multilocularis neuropeptide FF receptor 2 0.0157 0.0915 0.0908
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0145 0.0841 0.0841
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0064 0.0762
Brugia malayi hypothetical protein 0.0016 0.0014 0.0011
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0207 0.1232 0.2076
Onchocerca volvulus 0.0145 0.0841 0.1411
Plasmodium vivax JmjC domain containing protein 0.0036 0.0139 0.0237
Loa Loa (eye worm) hypothetical protein 0.0062 0.0309 0.0306
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0162 0.0159
Brugia malayi Papain family cysteine protease containing protein 0.0207 0.1232 0.1229
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0157 0.0915 0.0915
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0162 0.0162
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0501 0.3114 0.5289
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0109 0.0109
Plasmodium falciparum serine repeat antigen 2 0.0207 0.1232 0.2098
Giardia lamblia Cysteine protease 0.0207 0.1232 0.2968
Echinococcus multilocularis glutamate receptor 2 0.0023 0.0059 0.0052
Brugia malayi Cathepsin L-like precursor 0.0932 0.5874 0.5873
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.005 0.0231 0.0223
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Brugia malayi AKH receptor 0.0157 0.0915 0.0912
Brugia malayi RNA binding protein 0.0096 0.0524 0.0521
Brugia malayi Cathepsin L-like precursor 0.0932 0.5874 0.5873
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0084 0.0081
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0021 0.0045 0.0539
Trypanosoma cruzi cruzipain precursor, putative 0.0294 0.1792 0.1792
Mycobacterium tuberculosis Probable acetyl-/propionyl-coenzyme A carboxylase alpha chain (alpha subunit) AccA2: biotin carboxylase + biotin carboxyl carrie 0.0062 0.0307 0.0493
Onchocerca volvulus Cathepsin L homolog 0.0207 0.1232 0.2079
Schistosoma mansoni neuropeptide receptor 0.0157 0.0915 0.0915
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0022
Schistosoma mansoni hypothetical protein 0.0157 0.0915 0.0915
Echinococcus granulosus allatostatin A receptor 0.0157 0.0915 0.0908
Giardia lamblia Cathepsin B precursor 0.0631 0.3944 1
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0036 0.0139 0.0139
Echinococcus granulosus glutamate receptor 2 0.0033 0.012 0.0112
Onchocerca volvulus 0.0638 0.3992 0.6789
Trichomonas vaginalis glucosylceramidase, putative 0.0227 0.1359 0.2294
Schistosoma mansoni protein phosphatase 2C 0.0036 0.0139 0.0139
Mycobacterium leprae conserved hypothetical protein 0.0145 0.0841 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Echinococcus granulosus sex peptide receptor 0.0157 0.0915 0.0908
Echinococcus multilocularis cathepsin L 0.0207 0.1232 0.1225
Giardia lamblia Cathepsin L precursor 0.0207 0.1232 0.2968
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0157 0.0915 0.0908
Brugia malayi MH1 domain containing protein 0.0025 0.0067 0.0064
Loa Loa (eye worm) hypothetical protein 0.0015 0.0008 0.0004
Echinococcus granulosus neuropeptide s receptor 0.0157 0.0915 0.0908
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.5874 1
Leishmania major cathepsin L-like protease 0.0932 0.5874 0.779
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0157 0.0915 0.0912
Brugia malayi Cathepsin L-like cysteine proteinase 0.0638 0.3992 0.399
Schistosoma mansoni hypothetical protein 0.003 0.0105 0.0105
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0084 0.0081
Echinococcus multilocularis fmrfamide receptor 0.0157 0.0915 0.0908
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0097 0.0531 0.0523
Mycobacterium ulcerans esterase/lipase LipP 0.0145 0.0841 1
Echinococcus granulosus sterol O acyltransferase 1 0.0169 0.0988 0.0981
Schistosoma mansoni neuropeptide F-like receptor 0.0157 0.0915 0.0915
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.081 0.0803
Schistosoma mansoni neuropeptide receptor 0.0157 0.0915 0.0915
Echinococcus multilocularis cathepsin L cysteine protease 0.0932 0.5874 0.5871
Echinococcus granulosus 7tm_1 domain containing protein 0.0157 0.0915 0.0908
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Brugia malayi hypothetical protein 0.0157 0.0915 0.0912
Chlamydia trachomatis acetyl-coenzyme A carboxylase carboxyl transferase subunit beta 0.0022 0.0051 0.1069
Echinococcus multilocularis Membrane bound O acyl transferase, MBOAT 0.0016 0.0016 0.0008
Entamoeba histolytica cysteine protease, putative 0.0501 0.3114 0.5289
Trypanosoma cruzi acetyl-CoA carboxylase, putative 0.0022 0.0051 0.0051
Leishmania major acetyl-CoA carboxylase, putative 0.0163 0.0951 0.1261
Loa Loa (eye worm) hypothetical protein 0.0294 0.1792 0.179
Leishmania major cathepsin L-like protease 0.1193 0.754 1
Leishmania major glycerol uptake protein, putative 0.0016 0.0016 0.0021
Brugia malayi jmjC domain containing protein 0.0036 0.0139 0.0136
Schistosoma mansoni phosphatidylserine receptor 0.0036 0.0139 0.0139
Trichomonas vaginalis D-aminoacylase, putative 0.0145 0.0841 0.1408
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.081 0.081
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0281 0.0478
Schistosoma mansoni glutamate receptor kainate 0.0025 0.0073 0.0073
Trichomonas vaginalis glucosylceramidase, putative 0.0328 0.2006 0.3397
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.754 1
Trichomonas vaginalis glucosylceramidase, putative 0.0215 0.1285 0.2167
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0039 0.0162 0.0215
Plasmodium falciparum cysteine proteinase falcipain 1 0.0501 0.3114 0.5301
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0501 0.3114 0.413
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0033 0.012 0.0112
Echinococcus multilocularis cpg binding protein 0.0028 0.0091 0.0083
Mycobacterium tuberculosis Probable pyruvate carboxylase Pca (pyruvic carboxylase) 0.0062 0.0307 0.0493
Plasmodium falciparum biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.0118 0.0663 0.1129
Schistosoma mansoni tar DNA-binding protein 0.0096 0.0524 0.0524
Echinococcus multilocularis lipoxygenase domain containing protein 0.0016 0.0014 0.0006
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0147 0.0849 0.0842
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0207 0.1232 0.2076
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0134 0.0768 0.0761
Trichomonas vaginalis ap endonuclease, putative 0.005 0.0231 0.0367
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Schistosoma mansoni rab6-interacting 0.0016 0.0014 0.0014
Echinococcus multilocularis cysteine protease 0.0932 0.5874 0.5871
Echinococcus granulosus g protein coupled receptor 0.0157 0.0915 0.0908
Echinococcus granulosus GPCR family 2 0.003 0.0105 0.0097
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0033 0.012 0.0112
Leishmania major cysteine peptidase A (CPA) 0.0932 0.5874 0.779
Echinococcus granulosus acetyl coenzyme A carboxylase 1 0.0163 0.0951 0.0943
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0039 0.0162 0.0245
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0157 0.0915 0.0908
Schistosoma mansoni hypothetical protein 0.0157 0.0915 0.0915
Mycobacterium leprae Probable propyonyl-CoA carboxylase beta chain 4 AccD4 (Pccase) 0.0022 0.0051 0.0076
Loa Loa (eye worm) cytochrome P450 0.0021 0.0045 0.0042
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0162 0.0215
Loa Loa (eye worm) cysteine protease 0.0932 0.5874 0.5873
Schistosoma mansoni DNA polymerase eta 0.0039 0.0162 0.0162
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0021 0.0045 0.0045
Echinococcus granulosus cathepsin L cysteine proteinase 0.0932 0.5874 0.5871
Trypanosoma cruzi cysteine peptidase, putative 0.1193 0.754 0.754
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0039 0.0162 0.0162
Schistosoma mansoni opsin-like receptor 0.0157 0.0915 0.0915
Echinococcus multilocularis cathepsin b 0.1577 1 1
Echinococcus granulosus lipoxygenase domain containing protein 0.0016 0.0014 0.0006
Trichomonas vaginalis glucosylceramidase, putative 0.0215 0.1285 0.2167
Echinococcus granulosus alpha 1A adrenergic receptor 0.0157 0.0915 0.0908
Plasmodium vivax glycylpeptide N-tetradecanoyltransferase, putative 0.011 0.0614 0.1045
Echinococcus granulosus cysteine protease 0.0501 0.3114 0.3109
Loa Loa (eye worm) hypothetical protein 0.0638 0.3992 0.399
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0016 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Leishmania major cytochrome p450-like protein 0.0021 0.0045 0.006
Loa Loa (eye worm) acetyltransferase 0.0147 0.0849 0.0846
Echinococcus granulosus tm gpcr rhodopsin 0.0503 0.3127 0.3122
Schistosoma mansoni biogenic amine (5HT) receptor 0.0157 0.0915 0.0915
Loa Loa (eye worm) TAR-binding protein 0.0096 0.0524 0.0521
Plasmodium vivax SET domain protein, putative 0.0102 0.0564 0.096
Trypanosoma cruzi cysteine proteinase, putative 0.0501 0.3114 0.3114
Onchocerca volvulus 0.0157 0.0915 0.1538
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.081 0.0803
Schistosoma mansoni hypothetical protein 0.003 0.0105 0.0105
Entamoeba histolytica cysteine protease, putative 0.0932 0.5874 1
Leishmania major cathepsin L-like protease 0.0932 0.5874 0.779
Onchocerca volvulus 0.0157 0.0915 0.1538
Loa Loa (eye worm) cathepsin B 0.0631 0.3944 0.3942
Giardia lamblia CDC72 0.011 0.0614 0.1364
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.081 0.0803
Loa Loa (eye worm) isocitrate dehydrogenase 0.0031 0.0109 0.0106
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0084 0.0111
Echinococcus multilocularis serotonin receptor 0.0157 0.0915 0.0908
Entamoeba histolytica cysteine protease, putative 0.0501 0.3114 0.5289
Mycobacterium ulcerans acetyl/propionyl CoA carboxylase subunit beta 0.0022 0.0051 0.0611
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0147 0.0849 0.0849
Mycobacterium tuberculosis Conserved protein 0.0145 0.0841 0.1408
Loa Loa (eye worm) hypothetical protein 0.0145 0.0841 0.0838
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0157 0.0915 0.0915
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.003 0.0105 0.0097
Brugia malayi RNA recognition motif domain containing protein 0.0096 0.0524 0.0521
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.081 0.081
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0033 0.012 0.0112
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0899 0.5659 0.5659
Trichomonas vaginalis glucosylceramidase, putative 0.0215 0.1285 0.2167
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0039 0.0162 0.0159
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.754 1
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.005 0.0231 0.0227
Echinococcus granulosus propionyl coenzyme A carboxylase beta chain 0.0022 0.0051 0.0044
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0035 0.0133 0.0177
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0062 0.0309 0.0309
Echinococcus granulosus Polycystic kidney disease protein 0.0016 0.0014 0.0006
Loa Loa (eye worm) hypothetical protein 0.0016 0.0016 0.0012
Echinococcus multilocularis neuropeptide receptor 0.0157 0.0915 0.0908
Trypanosoma cruzi glycerol uptake protein, putative 0.0016 0.0016 0.0016
Trypanosoma brucei importin beta-1 subunit, putative 0.0015 0.0008 0.001
Echinococcus granulosus g protein coupled receptor 0.0157 0.0915 0.0908
Schistosoma mansoni glutamate receptor NMDA 0.006 0.0297 0.0297
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0157 0.0915 0.0912
Brugia malayi MH1 domain containing protein 0.0025 0.0067 0.0064
Brugia malayi Doublecortin family protein 0.0016 0.0014 0.0011
Echinococcus granulosus metabotropic glutamate receptor 2 0.0026 0.0079 0.0071
Trypanosoma brucei importin beta-1 subunit, putative 0.0015 0.0008 0.001
Entamoeba histolytica cysteine protease, putative 0.0501 0.3114 0.5289
Echinococcus multilocularis glycylpeptide N tetradecanoyltransferase 0.011 0.0614 0.0607
Echinococcus granulosus cathepsin l1 0.0932 0.5874 0.5871
Leishmania major cathepsin L-like protease 0.0932 0.5874 0.779
Echinococcus multilocularis JmjC domain containing protein 4 0.0036 0.0139 0.0131
Toxoplasma gondii acetyl-coA carboxylase ACC2 0.0163 0.0951 0.1618
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.754 1
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Echinococcus multilocularis acetyl coenzyme A carboxylase 1 0.0163 0.0951 0.0943
Echinococcus granulosus ankyrin repeat protein 0.0161 0.0941 0.0933
Trypanosoma cruzi cysteine peptidase, putative 0.0294 0.1792 0.1792
Schistosoma mansoni leukocyte receptor cluster (lrc) member 4 protein 0.0016 0.0016 0.0016
Schistosoma mansoni membrane-bound acyltransferase/hhat 0.0016 0.0016 0.0016
Schistosoma mansoni glutamate receptor AMPA 0.0025 0.0073 0.0073
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0067 0.006
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0932 0.5874 1
Leishmania major DNA polymerase kappa, putative 0.0039 0.0162 0.0215
Echinococcus multilocularis cathepsin b 0.1577 1 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0064 0.0082
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0157 0.0915 0.0915
Loa Loa (eye worm) glutamate receptor 0.0031 0.0106 0.0102
Echinococcus multilocularis diacylglycerol O acyltransferase 1 0.0016 0.0016 0.0008
Brugia malayi MBOAT family protein 0.0016 0.0016 0.0012
Brugia malayi jmjC domain containing protein 0.0036 0.0139 0.0136
Brugia malayi acetyltransferase, GNAT family protein 0.0147 0.0849 0.0846
Brugia malayi MBOAT family protein 0.0016 0.0016 0.0012
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0109 0.0186
Entamoeba histolytica cysteine proteinase 1, putative 0.0501 0.3114 0.5289
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0141 0.081 0.0807
Plasmodium falciparum serine repeat antigen 1 0.0207 0.1232 0.2098
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0631 0.3944 0.3944
Schistosoma mansoni o-acyltransferase (membrane bound) domain containing protein 0.0016 0.0016 0.0016
Brugia malayi jmjC domain containing protein 0.0036 0.0139 0.0136
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0207 0.1232 0.2076
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0157 0.0915 0.0915
Echinococcus granulosus lysine specific demethylase 5A 0.0136 0.0778 0.0771
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0145 0.0841 0.0838
Onchocerca volvulus 0.0027 0.0084 0.0119
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Loa Loa (eye worm) hypothetical protein 0.0145 0.0841 0.0838
Schistosoma mansoni loxhd1 0.0016 0.0014 0.0014
Mycobacterium tuberculosis Probable esterase LipL 0.0145 0.0841 0.1408
Giardia lamblia Cathepsin B precursor 0.0207 0.1232 0.2968
Trichomonas vaginalis glucosylceramidase, putative 0.0328 0.2006 0.3397
Echinococcus granulosus lamin dm0 0.0027 0.0084 0.0076
Trichomonas vaginalis glucosylceramidase, putative 0.0227 0.1359 0.2294
Echinococcus multilocularis neuropeptide Y receptor 0.0157 0.0915 0.0908
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0207 0.1232 0.1232
Loa Loa (eye worm) MH2 domain-containing protein 0.036 0.2214 0.2211
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0187 0.0179
Echinococcus multilocularis neuropeptides capa receptor 0.0157 0.0915 0.0908
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0157 0.0915 0.0912
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0039 0.0162 0.025
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0145 0.0841 0.1408
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0162 0.0159
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0067 0.006
Loa Loa (eye worm) hypothetical protein 0.0096 0.0524 0.0521
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0207 0.1232 0.2098
Schistosoma mansoni pyruvate carboxylase 0.0062 0.0307 0.0307
Loa Loa (eye worm) hypothetical protein 0.0294 0.1792 0.179
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0932 0.5874 0.5871
Loa Loa (eye worm) CXXC zinc finger family protein 0.0027 0.0081 0.0078
Brugia malayi Metabotropic glutamate receptor precursor. 0.0031 0.0106 0.0102
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0157 0.0915 0.0908
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Loa Loa (eye worm) neuropeptide F receptor 0.0157 0.0915 0.0912
Echinococcus granulosus intermediate filament protein 0.0027 0.0084 0.0076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.5874 1
Loa Loa (eye worm) hypothetical protein 0.0099 0.0545 0.0542
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0207 0.1232 0.2076
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0157 0.0915 0.0915
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Echinococcus multilocularis smad 0.0025 0.0067 0.006
Schistosoma mansoni hypothetical protein 0.0555 0.346 0.346
Brugia malayi Tachykinin-like peptides receptor 99D 0.0157 0.0915 0.0912
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0021 0.0045 0.0045
Onchocerca volvulus 0.0157 0.0915 0.1538
Entamoeba histolytica cysteine protease, putative 0.0501 0.3114 0.5289
Echinococcus multilocularis lysine specific demethylase 6a 0.0036 0.0139 0.0131
Echinococcus granulosus jumonji domain containing 1A 0.0036 0.0139 0.0131
Echinococcus multilocularis lamin 0.0027 0.0084 0.0076
Echinococcus granulosus glutamate NMDA receptor subunit 0.006 0.0297 0.029
Loa Loa (eye worm) melatonin receptor type 1A 0.0157 0.0915 0.0912
Onchocerca volvulus 0.0157 0.0915 0.1538
Brugia malayi hypothetical protein 0.0157 0.0915 0.0912
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.5874 1
Loa Loa (eye worm) hypothetical protein 0.0145 0.0841 0.0838
Leishmania major hypothetical protein, conserved 0.0145 0.0841 0.1115
Brugia malayi Hhat protein 0.0016 0.0016 0.0012
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0109 0.0186
Trypanosoma cruzi GUP1, putative 0.0016 0.0016 0.0016
Trypanosoma cruzi cytochrome P450, putative 0.0073 0.0379 0.0379
Brugia malayi putative neuropeptide receptor NPR1 0.0157 0.0915 0.0912
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.1001 0.6314 0.6311
Echinococcus multilocularis cathepsin L cysteine protease 0.0932 0.5874 0.5871
Loa Loa (eye worm) N-myristoyltransferase 2 0.011 0.0614 0.0611
Schistosoma mansoni propionyl-CoA carboxylase beta chain mitochondrial precursor 0.0022 0.0051 0.0051
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.5874 1
Schistosoma mansoni smad 0.0025 0.0067 0.0067
Onchocerca volvulus 0.0145 0.0841 0.1411
Entamoeba histolytica cysteine proteinase, putative 0.0501 0.3114 0.5289
Plasmodium vivax multidomain scavenger receptor, putative 0.0016 0.0014 0.0024
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0021 0.0045 0.0539
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1577 1 1
Echinococcus granulosus fmrfamide receptor 0.0157 0.0915 0.0908
Loa Loa (eye worm) hypothetical protein 0.0638 0.3992 0.399
Schistosoma mansoni acetyl-CoA carboxylase 0.0163 0.0951 0.0951
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Brugia malayi ORL1-like opioid receptor 0.0157 0.0915 0.0912
Echinococcus granulosus lysine specific demethylase 6a 0.0036 0.0139 0.0131
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0162 0.0162
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0021 0.0045 0.0539
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0033 0.012 0.0112
Giardia lamblia Cathepsin B precursor 0.0631 0.3944 1
Echinococcus granulosus glutamate receptor NMDA 0.005 0.023 0.0223
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0207 0.1232 0.2098
Echinococcus granulosus o acyltransferase membrane bound domain 0.0016 0.0016 0.0008
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Plasmodium vivax hypothetical protein, conserved 0.0145 0.0841 0.1431
Echinococcus granulosus lamin 0.0027 0.0084 0.0076
Schistosoma mansoni amine GPCR 0.0157 0.0915 0.0915
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0157 0.0915 0.0908
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0157 0.0915 0.0915
Schistosoma mansoni hypothetical protein 0.0157 0.0915 0.0915
Brugia malayi CXXC zinc finger family protein 0.0027 0.0081 0.0078
Trypanosoma cruzi N-myristoyl transferase, putative 0.011 0.0614 0.0614
Loa Loa (eye worm) hypothetical protein 0.0145 0.0841 0.0838
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.005 0.0231 0.0393
Brugia malayi Papain family cysteine protease containing protein 0.0207 0.1232 0.1229
Echinococcus multilocularis cathepsin L 0.0501 0.3114 0.3109
Mycobacterium ulcerans acetyl-/propionyl-coenzyme a carboxylase alpha chain AccA1 0.0062 0.0307 0.3647
Trichomonas vaginalis glucosylceramidase, putative 0.0328 0.2006 0.3397
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0145 0.0841 0.0838
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0031 0.0109 0.0145
Schistosoma mansoni cellular tumor antigen P53 0.0099 0.0545 0.0545
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0064 0.0085
Leishmania major hypothetical protein, conserved 0.0016 0.0016 0.0021
Schistosoma mansoni jumonji/arid domain-containing protein 0.0136 0.0778 0.0778
Loa Loa (eye worm) hhat protein 0.0016 0.0016 0.0012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.754 1
Schistosoma mansoni hypothetical protein 0.0555 0.346 0.346
Echinococcus multilocularis cysteine protease 0.0932 0.5874 0.5871
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0328 0.2006 0.2003
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0102 0.0564 0.0564
Loa Loa (eye worm) transcription factor SMAD2 0.036 0.2214 0.2211
Echinococcus granulosus neuropeptide FF receptor 2 0.0157 0.0915 0.0908
Brugia malayi Carboxyl transferase domain containing protein 0.0157 0.0914 0.0911
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0021 0.0045 0.0539
Brugia malayi MBOAT family protein 0.0016 0.0016 0.0012
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.5874 1
Entamoeba histolytica cysteine protease, putative 0.0501 0.3114 0.5289
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.081 0.081
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.5874 1
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0328 0.2006 0.2003
Onchocerca volvulus 0.0027 0.0084 0.0119
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0021 0.0045 0.0539
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 5 AccD5 0.0022 0.0051 0.0611
Onchocerca volvulus 0.0157 0.0915 0.1538
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0207 0.1232 0.1229
Schistosoma mansoni cathepsin F (C01 family) 0.0932 0.5874 0.5874
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Giardia lamblia Cathepsin B precursor 0.0207 0.1232 0.2968
Echinococcus granulosus protein cysteine N palmitoyltransferase 0.0016 0.0016 0.0008
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0021 0.0045 0.0539
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0035 0.0133 0.0126
Treponema pallidum exodeoxyribonuclease (exoA) 0.005 0.0231 1
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.003 0.0105 0.0101
Schistosoma mansoni growth hormone secretagogue receptor 0.0157 0.0915 0.0915
Giardia lamblia Cathepsin L precursor 0.0207 0.1232 0.2968
Echinococcus multilocularis musashi 0.0027 0.0084 0.0076
Plasmodium vivax vivapain-2 0.0932 0.5874 1
Onchocerca volvulus 0.0027 0.0081 0.0115
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0157 0.0915 0.0908
Schistosoma mansoni intermediate filament proteins 0.0027 0.0084 0.0084
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0062 0.0307 0.0407
Echinococcus granulosus rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Echinococcus multilocularis phd:f box containing protein 0.0036 0.0139 0.0131
Echinococcus granulosus smad 0.0025 0.0067 0.006
Echinococcus multilocularis membrane bound acyltransferase:hhat 0.0016 0.0016 0.0008
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0031 0.0109 0.0102
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0102 0.0564 0.0564
Mycobacterium leprae Probable bifunctional protein acetyl-/propionyl-coenzyme A carboxylase, alpha chain AccA3 (BccP) 0.0062 0.0307 0.3285
Leishmania major glycerol uptake protein, putative 0.0016 0.0016 0.0021
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0157 0.0915 0.0915
Trypanosoma cruzi cysteine peptidase, putative 0.0932 0.5874 0.5874
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0096 0.0524 0.0521
Trypanosoma brucei cysteine peptidase C (CPC) 0.0631 0.3944 0.523
Mycobacterium ulcerans pyruvate carboxylase 0.0062 0.0307 0.3647
Entamoeba histolytica cysteine protease, putative 0.0501 0.3114 0.5289
Trypanosoma cruzi 3-methylcrotonoyl-CoA carboxylase beta subunit, putative 0.0022 0.0051 0.0051
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Mycobacterium leprae ACETYL/PROPIONYL-CoA CARBOXYLASE (BETA SUBUNIT) ACCD6 0.0022 0.0051 0.0076
Loa Loa (eye worm) ctsf protein 0.0932 0.5874 0.5873
Echinococcus multilocularis jumonji domain containing 1A 0.0036 0.0139 0.0131
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0021 0.0045 0.0539
Trichomonas vaginalis D-aminoacylase, putative 0.0145 0.0841 0.1408
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0023 0.0059 0.0056
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0021 0.0045 0.0539
Schistosoma mansoni amine GPCR 0.0157 0.0915 0.0915
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Brugia malayi Trypsin family protein 0.0062 0.0309 0.0306
Echinococcus granulosus membrane bound acyltransferase:hhat 0.0016 0.0016 0.0008
Mycobacterium ulcerans propionyl-CoA carboxylase beta chain 4 AccD4 0.0022 0.0051 0.0611
Entamoeba histolytica cysteine protease, putative 0.0501 0.3114 0.5289
Brugia malayi larval opioid receptor 0.0157 0.0915 0.0912
Schistosoma mansoni cpg binding protein 0.0028 0.0091 0.0091
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0021 0.0045 0.006
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0031 0.0109 0.0109
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Loa Loa (eye worm) doublecortin family protein 0.0016 0.0014 0.0011
Leishmania major carboxylase, putative 0.0062 0.0307 0.0407
Brugia malayi cathepsin F-like cysteine proteinase 0.0207 0.1232 0.1229
Giardia lamblia Cysteine protease 0.0207 0.1232 0.2968
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0064 0.0762
Brugia malayi GnHR receptor homolog 0.0157 0.0915 0.0912
Onchocerca volvulus 0.0157 0.0915 0.1538
Entamoeba histolytica cysteine protease, putative 0.0501 0.3114 0.5289
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.006 0.0297 0.029
Echinococcus granulosus geminin 0.0555 0.346 0.3455
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Schistosoma mansoni cathepsin C 0.0207 0.1232 0.1232
Plasmodium falciparum importin beta, putative 0.0015 0.0008 0.0013
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0162 0.0162
Echinococcus granulosus tm gpcr rhodopsin 0.0157 0.0915 0.0908
Brugia malayi Cathepsin L-like precursor 0.0638 0.3992 0.399
Entamoeba histolytica exodeoxyribonuclease III, putative 0.005 0.0231 0.0367
Schistosoma mansoni neuropeptide F-like receptor 0.0157 0.0915 0.0915
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0157 0.0915 0.0908
Echinococcus granulosus neuropeptide receptor 0.0157 0.0915 0.0908
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Echinococcus multilocularis lamin dm0 0.0027 0.0084 0.0076
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0207 0.1232 0.2076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0207 0.1232 0.2076
Brugia malayi Papain family cysteine protease containing protein 0.0501 0.3114 0.3112
Trypanosoma brucei glycerol uptake protein, putative 0.0016 0.0016 0.0021
Schistosoma mansoni biogenic amine receptor 0.0157 0.0915 0.0915
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0021 0.0045 0.0045
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0011
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0207 0.1232 0.2098
Entamoeba histolytica cysteine proteinase, putative 0.0501 0.3114 0.5289
Schistosoma mansoni opsin-like receptor 0.0157 0.0915 0.0915
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0157 0.0915 0.0912
Loa Loa (eye worm) hypothetical protein 0.0169 0.0988 0.0985
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0022
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.003 0.0105 0.0097
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0207 0.1232 0.1232
Echinococcus granulosus metabotropic glutamate receptor 5 0.0036 0.0144 0.0136
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0102 0.0564 0.0557
Giardia lamblia Hypothetical protein 0.0207 0.1232 0.2968
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0067 0.006
Brugia malayi hypothetical protein 0.0157 0.0915 0.0912
Echinococcus multilocularis ankyrin repeat protein 0.0161 0.0941 0.0933
Echinococcus granulosus JmjC domain containing protein 4 0.0036 0.0139 0.0131
Plasmodium vivax vivapain-1 0.0501 0.3114 0.5301
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.5874 1
Onchocerca volvulus 0.0932 0.5874 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0145 0.0841 0.1408
Trichomonas vaginalis glucosylceramidase, putative 0.0215 0.1285 0.2167
Trypanosoma brucei unspecified product 0.0027 0.0084 0.0111
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0033 0.012 0.0112
Echinococcus multilocularis beta LACTamase domain containing family member 0.0145 0.0841 0.0834
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0067 0.006
Brugia malayi putative neuropeptide receptor 0.0157 0.0915 0.0912
Onchocerca volvulus Neuropeptide F receptor homolog 0.0157 0.0915 0.1538
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Echinococcus multilocularis fmrfamide receptor 0.0157 0.0915 0.0908
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0929 0.5854 1
Echinococcus granulosus tar DNA binding protein 0.0096 0.0524 0.0517
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0638 0.3992 0.6788
Loa Loa (eye worm) hypothetical protein 0.0036 0.0139 0.0136
Entamoeba histolytica cysteine protease, putative 0.0501 0.3114 0.5289
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.754 1
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0073 0.0379 0.4511
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0021 0.0045 0.0045
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.5874 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Loa Loa (eye worm) hypothetical protein 0.0102 0.0564 0.0561
Brugia malayi latrophilin 2 splice variant baaae 0.0066 0.033 0.0327
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0021 0.0045 0.0045
Giardia lamblia Cathepsin L precursor 0.0207 0.1232 0.2968
Echinococcus granulosus g-protein coupled receptor 0.0157 0.0915 0.0908
Brugia malayi hypothetical protein 0.0016 0.0014 0.0011
Schistosoma mansoni N-myristoyltransferase 0.011 0.0614 0.0614
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0157 0.0915 0.0915
Plasmodium vivax diacylglycerol O-acyltransferase, putative 0.0016 0.0016 0.0027
Schistosoma mansoni hypothetical protein 0.0066 0.033 0.033
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0157 0.0915 0.0915
Loa Loa (eye worm) fibroinase 0.0932 0.5874 0.5873
Brugia malayi jmjC domain containing protein 0.0134 0.0768 0.0765
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0021 0.0045 0.0045
Onchocerca volvulus 0.0157 0.0915 0.1538
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.005 0.0231 0.0393
Toxoplasma gondii hypothetical protein 0.0016 0.0016 0.0027
Echinococcus multilocularis neuropeptide receptor 0.0157 0.0915 0.0908
Entamoeba histolytica cysteine protease, putative 0.0207 0.1232 0.2076
Trypanosoma cruzi N-myristoyl transferase, putative 0.011 0.0614 0.0614
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0039 0.0162 0.0154
Echinococcus granulosus propionyl coenzyme A carboxylase alpha chain 0.0062 0.0307 0.0299
Entamoeba histolytica cysteine protease, putative 0.0207 0.1232 0.2076
Leishmania major cathepsin L-like protease 0.1193 0.754 1
Onchocerca volvulus 0.0157 0.0915 0.1538
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0207 0.1232 0.2098
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0021 0.0045 0.0045
Echinococcus multilocularis Smad4 0.0025 0.0067 0.006
Brugia malayi cathepsin L precursor 0.0207 0.1232 0.1229
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0932 0.5874 1
Schistosoma mansoni lipoxygenase 0.0068 0.0344 0.0344
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0036 0.0139 0.0237
Loa Loa (eye worm) hypothetical protein 0.0018 0.0025 0.0022
Giardia lamblia Cathepsin L precursor 0.0207 0.1232 0.2968
Trypanosoma cruzi cysteine proteinase, putative 0.0501 0.3114 0.3114
Brugia malayi Cathepsin L-like precursor 0.0932 0.5874 0.5873
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0102 0.0564 0.0564
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0064 0.0235
Brugia malayi diacylglycerol acyltransferase 0.0016 0.0016 0.0012
Onchocerca volvulus 0.0932 0.5874 1
Echinococcus granulosus cathepsin b 0.1577 1 1
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0064 0.0061
Brugia malayi G protein-coupled receptor F59B2.13 0.0157 0.0915 0.0912
Echinococcus granulosus hypothetical protein 0.0157 0.0915 0.0908
Onchocerca volvulus 0.0932 0.5874 1
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.005 0.0231 0.0363
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0162 0.0215
Schistosoma mansoni myosin xvIII 0.0157 0.0915 0.0915
Giardia lamblia Encystation-specific protease 0.0207 0.1232 0.2968
Giardia lamblia Cysteine protease 0.0207 0.1232 0.2968
Giardia lamblia Cathepsin B precursor 0.0207 0.1232 0.2968
Trichomonas vaginalis esterase, putative 0.0145 0.0841 0.1408
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0021 0.0045 0.0045
Toxoplasma gondii HEAT repeat-containing protein 0.0015 0.0008 0.0013
Brugia malayi cathepsin Z-like cysteine proteinase 0.0207 0.1232 0.1229
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.005 0.0231 0.0231
Loa Loa (eye worm) hypothetical protein 0.0062 0.0309 0.0306
Echinococcus multilocularis g protein coupled receptor 0.0157 0.0915 0.0908
Echinococcus multilocularis rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Brugia malayi beta-lactamase family protein 0.0145 0.0841 0.0838
Brugia malayi TAR-binding protein 0.0096 0.0524 0.0521
Echinococcus multilocularis neuropeptide Y receptor 0.0157 0.0915 0.0908
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0207 0.1232 0.1232
Loa Loa (eye worm) neuropeptide F receptor 0.0157 0.0915 0.0912
Loa Loa (eye worm) hypothetical protein 0.0036 0.0144 0.014
Echinococcus granulosus tachykinin peptides receptor 99D 0.0157 0.0915 0.0908
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0162 0.0215
Schistosoma mansoni jumonji domain containing protein 0.0036 0.0139 0.0139
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0501 0.3114 0.413
Mycobacterium ulcerans acetyl-coenzyme a carboxylase carboxyl transferase (subunit beta) AccD3 0.0022 0.0051 0.0611
Schistosoma mansoni alpha-1 adrenergic receptor 0.0157 0.0915 0.0915
Schistosoma mansoni opsin-like receptor 0.0157 0.0915 0.0915
Onchocerca volvulus 0.0062 0.0309 0.0503
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0162 0.0215
Trypanosoma cruzi acetyl-CoA carboxylase 0.0101 0.0554 0.0554
Trypanosoma cruzi 3-methylcrotonyl-CoA carboxylase, putative 0.0062 0.0307 0.0307
Brugia malayi Isocitrate dehydrogenase 0.0031 0.0109 0.0106
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0157 0.0915 0.0915
Loa Loa (eye worm) CYP4Cod1 0.0073 0.0379 0.0376
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0163 0.095 0.0947
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0207 0.1232 0.1232
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0029 0.0097 0.0097
Echinococcus multilocularis glutamate receptor 2 0.0025 0.0073 0.0066
Trypanosoma cruzi glycerol uptake protein, putative 0.0016 0.0016 0.0016
Entamoeba histolytica cysteine proteinase, putative 0.0638 0.3992 0.6788
Loa Loa (eye worm) TYRA-2 protein 0.0157 0.0915 0.0912
Mycobacterium ulcerans hypothetical protein 0.0024 0.0064 0.0762
Trypanosoma cruzi cysteine protease, putative 0.0501 0.3114 0.3114
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.1193 0.754 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0157 0.0915 0.0915
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.003 0.0105 0.0097
Loa Loa (eye worm) hypothetical protein 0.0207 0.1232 0.1229
Schistosoma mansoni jumonji/arid domain-containing protein 0.0136 0.0778 0.0778
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0036 0.0139 0.0139
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.5874 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0102 0.0564 0.0564
Echinococcus multilocularis G protein coupled receptor 139 0.0157 0.0915 0.0908
Echinococcus granulosus Smad4 0.0025 0.0067 0.006
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0109 0.0102
Loa Loa (eye worm) RNA binding protein 0.0096 0.0524 0.0521
Onchocerca volvulus 0.0157 0.0915 0.1538
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0067 0.0067
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0932 0.5874 1
Brugia malayi Glutamate receptor 2 precursor 0.0025 0.0073 0.007
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0164 0.0252
Plasmodium falciparum serine repeat antigen 7 0.0207 0.1232 0.2098
Entamoeba histolytica cysteine protease, putative 0.0207 0.1232 0.2076
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0098 0.0536 0.0529
Onchocerca volvulus 0.0157 0.0915 0.1538
Plasmodium vivax vivapain-2 0.0932 0.5874 1
Echinococcus granulosus o acyltransferase membrane bound domain 0.0016 0.0016 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0162 0.0215
Loa Loa (eye worm) carboxyl transferase domain-containing protein 0.0157 0.0914 0.0911
Giardia lamblia Cathepsin B precursor 0.0631 0.3944 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0157 0.0915 0.0908
Brugia malayi cathepsin L-like cysteine proteinase 0.0207 0.1232 0.1229
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0932 0.5874 1
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0162 0.1927
Onchocerca volvulus Huntingtin homolog 0.0075 0.0391 0.0643
Trichomonas vaginalis glucosylceramidase, putative 0.0328 0.2006 0.3397
Echinococcus granulosus 7TM GPCR rhodopsin 0.0157 0.0915 0.0908
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0021 0.0045 0.0539
Onchocerca volvulus 0.0932 0.5874 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0932 0.5874 1
Onchocerca volvulus 0.0157 0.0915 0.1538
Echinococcus multilocularis protein cysteine N palmitoyltransferase 0.0016 0.0016 0.0008
Giardia lamblia Cathepsin L-like protease 0.0207 0.1232 0.2968
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0709 0.4444 0.4442
Echinococcus granulosus glutamate receptor 2 0.0023 0.0059 0.0052
Entamoeba histolytica cysteine protease, putative 0.0501 0.3114 0.5289
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0109 0.0102
Brugia malayi Dopamine receptor protein 1 0.0157 0.0915 0.0912
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0035 0.0133 0.0126
Entamoeba histolytica cysteine proteinase 2 0.0501 0.3114 0.5289
Echinococcus multilocularis g-protein coupled receptor 0.0157 0.0915 0.0908
Loa Loa (eye worm) membrane bound O-acyltransferase domain containing 1 0.0016 0.0016 0.0012
Schistosoma mansoni tar DNA-binding protein 0.0096 0.0524 0.0524
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0021 0.0045 0.0045
Echinococcus granulosus dna polymerase eta 0.0039 0.0162 0.0154
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0102 0.0564 0.096
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0062 0.0309 0.0309
Brugia malayi sulfakinin receptor protein 0.0157 0.0915 0.0912
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0187 0.0318
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0157 0.0915 0.0915
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0157 0.0915 0.0908
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0932 0.5874 0.5873
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0207 0.1232 0.1229
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0021 0.0045 0.0539
Giardia lamblia Cathepsin L precursor 0.0207 0.1232 0.2968
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0207 0.1232 0.2968
Brugia malayi G-protein coupled receptor 0.0157 0.0915 0.0912
Schistosoma mansoni hypothetical protein 0.0163 0.095 0.095
Trichomonas vaginalis penicillin-binding protein, putative 0.0145 0.0841 0.1408
Loa Loa (eye worm) hypothetical protein 0.0036 0.0139 0.0136
Trypanosoma brucei unspecified product 0.0039 0.0162 0.0215
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Loa Loa (eye worm) cytochrome P450 family protein 0.0073 0.0379 0.0376
Trypanosoma cruzi cysteine peptidase, putative 0.1193 0.754 0.754
Schistosoma mansoni adenoreceptor 0.0157 0.0915 0.0915
Schistosoma mansoni glutamate receptor kainate 0.0025 0.0073 0.0073
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.005 0.0231 0.0306
Trypanosoma brucei 3-methylcrotonyl-CoA carboxylase alpha subunit, putative 0.0062 0.0307 0.0407
Mycobacterium tuberculosis Probable lipase LipE 0.0145 0.0841 0.1408
Schistosoma mansoni biogenic amine receptor 0.0157 0.0915 0.0915
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1577 1 1
Chlamydia trachomatis biotin carboxylase 0.0056 0.027 1
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0207 0.1232 0.1232
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.5874 1
Plasmodium falciparum serine repeat antigen 4 0.0207 0.1232 0.2098
Echinococcus multilocularis glutamate receptor NMDA 0.005 0.023 0.0223
Echinococcus multilocularis Polycystic kidney disease protein 0.0016 0.0014 0.0006
Trichomonas vaginalis N-myristoyl transferase, putative 0.0072 0.0373 0.0609
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0207 0.1232 0.2076
Loa Loa (eye worm) hypothetical protein 0.0016 0.0016 0.0012
Toxoplasma gondii cathepsin CPL 0.0932 0.5874 1
Loa Loa (eye worm) hypothetical protein 0.0075 0.0391 0.0388
Schistosoma mansoni neuropeptide receptor 0.0157 0.0915 0.0915
Schistosoma mansoni hypothetical protein 0.0016 0.0014 0.0014
Brugia malayi RNA, U transporter 1 0.0043 0.0187 0.0184
Brugia malayi Dopamine receptor 0.0157 0.0915 0.0912
Echinococcus multilocularis 0.0021 0.0045 0.0038
Schistosoma mansoni cytochrome P450 0.0021 0.0045 0.0045
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0033 0.012 0.0112
Loa Loa (eye worm) hypothetical protein 0.0152 0.0883 0.088
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0109 0.0102
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0164 0.0278
Schistosoma mansoni smad1 5 8 and 0.0025 0.0067 0.0067
Schistosoma mansoni biogenic amine (5HT) receptor 0.0157 0.0915 0.0915
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0164 0.0196
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0503 0.3127 0.3122
Mycobacterium tuberculosis Acetyl/propionyl-CoA carboxylase (beta subunit) AccD6 0.0022 0.0051 0.0056
Plasmodium vivax unspecified product 0.0501 0.3114 0.5301
Leishmania major glycerol uptake protein, putative 0.0016 0.0016 0.0021
Loa Loa (eye worm) MBOAT family protein 0.0016 0.0016 0.0012
Giardia lamblia DINP protein human, muc B family 0.0039 0.0162 0.0192
Echinococcus granulosus cathepsin L cysteine protease 0.0501 0.3114 0.3109
Toxoplasma gondii cathepsin B 0.0631 0.3944 0.6714
Echinococcus multilocularis rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Entamoeba histolytica deoxycytidyl transferase, putative 0.0039 0.0162 0.025
Echinococcus multilocularis rhodopsin orphan GPCR 0.0157 0.0915 0.0908
Schistosoma mansoni glutamate receptor AMPA 0.0025 0.0073 0.0073
Echinococcus granulosus cathepsin l cysteine peptidase 0.0932 0.5874 0.5871
Schistosoma mansoni glutamate receptor NMDA 0.0083 0.044 0.044
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0162 0.0215
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0031 0.0109 0.0186
Echinococcus granulosus cathepsin L 0.0501 0.3114 0.3109
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0932 0.5874 1
Echinococcus multilocularis serotonin receptor 0.0157 0.0915 0.0908
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0097 0.0531 0.0523
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0207 0.1232 0.2076
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0033 0.012 0.0112
Schistosoma mansoni tar DNA-binding protein 0.0096 0.0524 0.0524
Brugia malayi hypothetical protein 0.0157 0.0915 0.0912
Trichomonas vaginalis conserved hypothetical protein 0.0207 0.1232 0.2076
Onchocerca volvulus 0.0207 0.1232 0.2079
Loa Loa (eye worm) glutamate receptor 2 0.0025 0.0073 0.007
Schistosoma mansoni amine GPCR 0.0157 0.0915 0.0915
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Entamoeba histolytica acetyl-coA carboxylase, putative 0.0028 0.0088 0.0123
Trypanosoma cruzi major cysteine proteinase, putative 0.0207 0.1232 0.1232
Onchocerca volvulus 0.0157 0.0915 0.1538
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0109 0.0145
Schistosoma mansoni ATP-binding cassette transporter 0.0025 0.0073 0.0073
Trichomonas vaginalis glucosylceramidase, putative 0.0328 0.2006 0.3397
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0162 0.0215
Onchocerca volvulus 0.0055 0.0265 0.0428
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0021 0.0045 0.0045
Echinococcus granulosus phd:f box containing protein 0.0036 0.0139 0.0131
Plasmodium vivax importin-beta 2, putative 0.0015 0.0008 0.0013
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0145 0.0841 0.1408
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1577 1 1
Trypanosoma cruzi hypothetical protein, conserved 0.0145 0.0841 0.0841
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0021 0.0045 0.0539
Brugia malayi MBOAT family protein 0.0016 0.0016 0.0012
Brugia malayi G protein-coupled receptor 0.0157 0.0915 0.0912
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0207 0.1232 0.2076
Onchocerca volvulus Cathepsin L homolog 0.0932 0.5874 1
Trichomonas vaginalis ap endonuclease, putative 0.005 0.0231 0.0367
Mycobacterium ulcerans acetyl-/propionyl-CoA carboxylase subunit beta 0.0022 0.0051 0.0611
Leishmania major glycerol uptake protein, putative 0.0016 0.0016 0.0021
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0932 0.5874 1
Brugia malayi hypothetical protein 0.0075 0.0391 0.0388
Echinococcus granulosus transient receptor potential cation channel 0.0166 0.0972 0.0965
Mycobacterium tuberculosis Conserved protein 0.0145 0.0841 0.1408
Toxoplasma gondii cytochrome p450 superfamily protein 0.0021 0.0045 0.0077
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.081 0.0803
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0162 0.0215
Plasmodium vivax unspecified product 0.0294 0.1792 0.3051
Plasmodium vivax biotin carboxylase subunit of acetyl CoA carboxylase, putative 0.0118 0.0663 0.1129
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0021 0.0045 0.0539
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0035 0.0133 0.0177
Loa Loa (eye worm) hypothetical protein 0.0207 0.1232 0.1229
Brugia malayi Latrophilin receptor protein 2 0.003 0.0105 0.0101
Loa Loa (eye worm) hypothetical protein 0.0016 0.0014 0.0011
Loa Loa (eye worm) latrophilin receptor protein 2 0.003 0.0105 0.0101
Loa Loa (eye worm) hypothetical protein 0.0157 0.0915 0.0912
Echinococcus granulosus nmda type glutamate receptor 0.0059 0.0291 0.0283
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0631 0.3944 0.6705
Schistosoma mansoni cathepsin s 0.0294 0.1792 0.1792

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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