Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0034 | 0.0456 | 0.1572 |
Plasmodium vivax | vivapain-2 | 0.0034 | 0.0456 | 0.162 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0022 | 0.0021 | 0.0021 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0034 | 0.0456 | 0.1511 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0022 | 0.003 | 0.003 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0034 | 0.0456 | 0.1511 |
Brugia malayi | calpain family protein 1 | 0.0057 | 0.1253 | 0.1253 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0022 | 0.003 | 0.003 |
Leishmania major | cathepsin L-like protease | 0.0034 | 0.0456 | 0.1572 |
Leishmania major | cathepsin L-like protease | 0.0034 | 0.0456 | 0.1572 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0034 | 0.0456 | 0.1511 |
Echinococcus multilocularis | cysteine protease | 0.0034 | 0.0456 | 0.0456 |
Brugia malayi | Cathepsin L-like precursor | 0.0034 | 0.0456 | 0.0456 |
Leishmania major | cathepsin L-like protease | 0.0034 | 0.0456 | 0.1572 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0034 | 0.0456 | 0.1511 |
Onchocerca volvulus | 0.0034 | 0.0456 | 0.9182 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0159 | 0.0481 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.0159 | 0.0159 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0034 | 0.0456 | 0.0456 |
Brugia malayi | Cathepsin L-like precursor | 0.0034 | 0.0456 | 0.0456 |
Plasmodium vivax | vivapain-2 | 0.0034 | 0.0456 | 0.162 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0104 | 0.2902 | 0.2902 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0034 | 0.0456 | 0.0456 |
Entamoeba histolytica | cysteine protease, putative | 0.0034 | 0.0456 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0034 | 0.0456 | 0.1511 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0034 | 0.0456 | 0.0456 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0022 | 0.0021 | 0.0021 |
Plasmodium vivax | vivapain-3 | 0.0022 | 0.0021 | 0.0075 |
Onchocerca volvulus | 0.0034 | 0.0456 | 0.9182 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0034 | 0.0456 | 0.1511 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0034 | 0.0456 | 0.1572 |
Plasmodium vivax | plasmepsin IV, putative | 0.0058 | 0.1304 | 0.463 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0034 | 0.0456 | 0.1511 |
Plasmodium falciparum | plasmepsin II | 0.0058 | 0.1304 | 0.459 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0034 | 0.0456 | 0.0456 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0034 | 0.0456 | 0.1572 |
Echinococcus granulosus | cathepsin l1 | 0.0034 | 0.0456 | 0.0456 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0034 | 0.0456 | 0.1511 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0022 | 0.0021 | 0.0021 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0034 | 0.0456 | 0.1511 |
Plasmodium falciparum | plasmepsin V | 0.0022 | 0.003 | 0.0031 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0034 | 0.0456 | 0.1511 |
Onchocerca volvulus | 0.0034 | 0.0456 | 0.9182 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0022 | 0.0021 | 0.0072 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.006 | 0.1345 | 0.1345 |
Echinococcus multilocularis | calpain family protein 1, d | 0.0042 | 0.0722 | 0.0722 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0026 | 0.0159 | 0.0159 |
Brugia malayi | calpain family protein 1 | 0.0057 | 0.1253 | 0.1253 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0034 | 0.0456 | 0.1572 |
Echinococcus granulosus | family C2 unassigned peptidase C02 family | 0.006 | 0.1345 | 0.1345 |
Onchocerca volvulus | 0.0034 | 0.0456 | 0.9182 | |
Echinococcus granulosus | cathepsin b | 0.0304 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0159 | 0.0159 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0034 | 0.0456 | 0.1572 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0034 | 0.0456 | 0.1511 |
Plasmodium vivax | unspecified product | 0.0022 | 0.0021 | 0.0075 |
Echinococcus granulosus | cathepsin l1 | 0.0026 | 0.0159 | 0.0159 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0034 | 0.0456 | 0.1572 |
Onchocerca volvulus | 0.0034 | 0.0456 | 0.9182 | |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0034 | 0.0456 | 0.1558 |
Echinococcus multilocularis | cathepsin b | 0.0304 | 1 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0034 | 0.0456 | 0.0456 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0022 | 0.0021 | 0.0021 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0022 | 0.0021 | 0.0021 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0034 | 0.0456 | 1 |
Echinococcus granulosus | cathepsin L | 0.0022 | 0.0021 | 0.0021 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0034 | 0.0456 | 0.1511 |
Loa Loa (eye worm) | cathepsin B | 0.0104 | 0.2902 | 0.2902 |
Plasmodium vivax | aspartyl proteinase, putative | 0.0022 | 0.003 | 0.0105 |
Brugia malayi | Cathepsin L-like precursor | 0.0034 | 0.0456 | 0.0456 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0034 | 0.0456 | 0.1558 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0304 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0034 | 0.0456 | 0.0456 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0034 | 0.0456 | 0.1511 |
Echinococcus multilocularis | cysteine protease | 0.0034 | 0.0456 | 0.0456 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0034 | 0.0456 | 0.0456 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0034 | 0.0456 | 0.0456 |
Echinococcus multilocularis | family C2 unassigned peptidase (C02 family) | 0.006 | 0.1345 | 0.1345 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0034 | 0.0456 | 0.1572 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0034 | 0.0456 | 0.1511 |
Giardia lamblia | Cathepsin B precursor | 0.0104 | 0.2902 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0034 | 0.0456 | 1 |
Onchocerca volvulus | 0.0026 | 0.0159 | 0.2795 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0026 | 0.0159 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0034 | 0.0456 | 0.1511 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0034 | 0.0456 | 0.1572 |
Echinococcus granulosus | cathepsin d lysosomal aspartyl protease | 0.0058 | 0.1304 | 0.1304 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0026 | 0.0159 | 0.0481 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0042 | 0.0722 | 0.0722 |
Plasmodium vivax | aspartyl protease, putative | 0.0101 | 0.2815 | 1 |
Trichomonas vaginalis | Clan AA, family A1, cathepsin D-like aspartic peptidase | 0.0058 | 0.1304 | 0.4451 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.1304 | 0.1304 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0022 | 0.003 | 0.003 |
Plasmodium vivax | aspartyl protease, putative | 0.0101 | 0.2815 | 1 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0022 | 0.0021 | 0.0021 |
Loa Loa (eye worm) | fibroinase | 0.0034 | 0.0456 | 0.0456 |
Onchocerca volvulus | 0.0034 | 0.0456 | 0.9182 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0034 | 0.0456 | 0.1511 |
Onchocerca volvulus | Cathepsin L homolog | 0.0034 | 0.0456 | 0.9182 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0304 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0304 | 1 | 1 |
Schistosoma mansoni | memapsin-2 (A01 family) | 0.0022 | 0.003 | 0.003 |
Echinococcus granulosus | cysteine protease | 0.0022 | 0.0021 | 0.0021 |
Leishmania major | cathepsin L-like protease | 0.0034 | 0.0456 | 0.1572 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0242 | 0.7805 | 0.7805 |
Echinococcus multilocularis | cathepsin L | 0.0022 | 0.0021 | 0.0021 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0034 | 0.0456 | 0.0456 |
Echinococcus multilocularis | cathepsin d (lysosomal aspartyl protease) | 0.0058 | 0.1304 | 0.1304 |
Plasmodium falciparum | plasmepsin IV | 0.0058 | 0.1304 | 0.459 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0104 | 0.2902 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0104 | 0.2902 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0104 | 0.2902 | 0.5 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0034 | 0.0456 | 0.0456 |
Plasmodium falciparum | plasmepsin IX | 0.0101 | 0.2815 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0034 | 0.0456 | 0.1511 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0022 | 0.003 | 0.003 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0034 | 0.0456 | 0.1558 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0034 | 0.0456 | 0.1511 |
Plasmodium vivax | vivapain-1 | 0.0022 | 0.0021 | 0.0075 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0022 | 0.003 | 0.003 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0058 | 0.1304 | 0.1304 |
Plasmodium falciparum | plasmepsin I | 0.0058 | 0.1304 | 0.459 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0034 | 0.0456 | 0.0456 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0034 | 0.0456 | 0.0456 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0034 | 0.0456 | 0.1572 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0304 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0034 | 0.0456 | 0.1511 |
Toxoplasma gondii | aspartyl proteinase (eimepsin), putative | 0.0058 | 0.1304 | 0.4435 |
Giardia lamblia | Cathepsin B precursor | 0.0104 | 0.2902 | 0.5 |
Plasmodium falciparum | plasmepsin VII | 0.0022 | 0.003 | 0.0031 |
Plasmodium falciparum | plasmepsin VI | 0.0058 | 0.1304 | 0.459 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0034 | 0.0456 | 0.1572 |
Onchocerca volvulus | 0.0035 | 0.0494 | 1 | |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0026 | 0.0159 | 0.0159 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0026 | 0.0159 | 0.0159 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0722 | 0.0722 |
Trypanosoma cruzi | cysteine protease, putative | 0.0022 | 0.0021 | 0.0021 |
Brugia malayi | Cathepsin L-like precursor | 0.0034 | 0.0456 | 0.0456 |
Leishmania major | cathepsin L-like protease | 0.0034 | 0.0456 | 0.1572 |
Onchocerca volvulus | 0.0034 | 0.0456 | 0.9182 | |
Brugia malayi | cathepsin L-like precursor | 0.0026 | 0.0159 | 0.0159 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0022 | 0.0021 | 0.0021 |
Plasmodium vivax | aspartyl proteinase, putative | 0.0058 | 0.1304 | 0.463 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.1253 | 0.1253 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0034 | 0.0456 | 0.1511 |
Schistosoma mansoni | cathepsin D (A01 family) | 0.0242 | 0.7805 | 0.7805 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0494 | 0.0494 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.1025 | 0.1025 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0034 | 0.0456 | 0.0456 |
Brugia malayi | Pepsin A precursor | 0.0022 | 0.003 | 0.003 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0034 | 0.0456 | 0.1511 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0057 | 0.1253 | 0.1253 |
Loa Loa (eye worm) | aspartic protease BmAsp-1 | 0.0022 | 0.003 | 0.003 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0304 | 1 | 1 |
Echinococcus multilocularis | calpain A | 0.006 | 0.1345 | 0.1345 |
Loa Loa (eye worm) | ctsf protein | 0.0034 | 0.0456 | 0.0456 |
Brugia malayi | Cathepsin L-like precursor | 0.0026 | 0.0159 | 0.0159 |
Echinococcus granulosus | cathepsin b | 0.0304 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0022 | 0.003 | 0.003 |
Leishmania major | cysteine peptidase A (CPA) | 0.0034 | 0.0456 | 0.1572 |
Onchocerca volvulus | Cathepsin L homolog | 0.0034 | 0.0456 | 0.9182 |
Toxoplasma gondii | aspartyl protease ASP1 | 0.0058 | 0.1304 | 0.4435 |
Plasmodium vivax | plasmepsin V, putative | 0.0022 | 0.003 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0159 | 0.0159 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0057 | 0.1253 | 0.1253 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.003 | 0.003 |
Leishmania major | cathepsin L-like protease | 0.0034 | 0.0456 | 0.1572 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.006 | 0.1345 | 0.1345 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0034 | 0.0456 | 0.1511 |
Leishmania major | cathepsin L-like protease | 0.0034 | 0.0456 | 0.1572 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0022 | 0.0021 | 0.0021 |
Echinococcus multilocularis | cathepsin b | 0.0304 | 1 | 1 |
Plasmodium falciparum | plasmepsin X | 0.0101 | 0.2815 | 1 |
Plasmodium falciparum | plasmepsin III | 0.0022 | 0.003 | 0.0031 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0034 | 0.0456 | 0.1511 |
Toxoplasma gondii | cathepsin CPL | 0.0034 | 0.0456 | 0.1485 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0159 | 0.0159 |
Loa Loa (eye worm) | hypothetical protein | 0.0304 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0034 | 0.0456 | 0.0456 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0034 | 0.0456 | 0.0456 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0034 | 0.0456 | 0.1572 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0022 | 0.0021 | 0.0021 |
Toxoplasma gondii | aspartyl protease ASP3 | 0.0101 | 0.2815 | 0.9697 |
Brugia malayi | hypothetical protein | 0.0022 | 0.003 | 0.003 |
Leishmania major | cathepsin L-like protease | 0.0034 | 0.0456 | 0.1572 |
Loa Loa (eye worm) | aspartyl protease 6 | 0.0022 | 0.003 | 0.003 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0104 | 0.2902 | 1 |
Loa Loa (eye worm) | aspartic protease BmAsp-2 | 0.0058 | 0.1304 | 0.1304 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0034 | 0.0456 | 0.1511 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0104 | 0.2902 | 0.2902 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0034 | 0.0456 | 0.0456 |
Brugia malayi | Eukaryotic aspartyl protease family protein | 0.0022 | 0.003 | 0.003 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0022 | 0.003 | 0.003 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0456 | 0.0456 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0022 | 0.003 | 0.003 |
Brugia malayi | aspartic protease BmAsp-2, identical | 0.0022 | 0.003 | 0.003 |
Onchocerca volvulus | Cathepsin F homolog | 0.0034 | 0.0456 | 0.9182 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0034 | 0.0456 | 0.0456 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0034 | 0.0456 | 0.1511 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.003 | 0.003 |
Plasmodium falciparum | plasmepsin VIII, putative | 0.0022 | 0.003 | 0.0031 |
Echinococcus granulosus | calpain A | 0.006 | 0.1345 | 0.1345 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0034 | 0.0456 | 0.0456 |
Schistosoma mansoni | subfamily A1A unassigned peptidase (A01 family) | 0.0022 | 0.003 | 0.003 |
Brugia malayi | aspartic protease BmAsp-1, identical | 0.0022 | 0.003 | 0.003 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0022 | 0.0021 | 0.0072 |
Plasmodium vivax | aspartyl protease, putative | 0.0022 | 0.003 | 0.0105 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0022 | 0.0021 | 0.0021 |
Toxoplasma gondii | cathepsin B | 0.0104 | 0.2902 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0034 | 0.0456 | 0.0456 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.