Detailed information for compound 73254

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 284.307 | Formula: C17H16O4
  • H donors: 1 H acceptors: 2 LogP: 3.6 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)c1cc(Oc2ccccc2)c2c(c1)OC(C2)(C)C
  • InChi: 1S/C17H16O4/c1-17(2)10-13-14(20-12-6-4-3-5-7-12)8-11(16(18)19)9-15(13)21-17/h3-9H,10H2,1-2H3,(H,18,19)
  • InChiKey: WONPRBCSQJOSHE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis cysteine protease 0.0027 0.041 0.041
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0034 0.0649 0.0649
Plasmodium vivax vivapain-3 0.0018 0.0083 0.1101
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.008 0.2302 0.69
Plasmodium vivax unspecified product 0.0018 0.0083 0.1101
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0034 0.0649 0.0649
Onchocerca volvulus 0.0034 0.0649 0.0603
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0034 0.0649 0.0649
Brugia malayi Cathepsin L-like precursor 0.0027 0.041 0.041
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.041 0.0521
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0755 0.0952
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Schistosoma mansoni chromatin regulatory protein sir2 0.0108 0.3336 0.3336
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.0083 0.0083
Onchocerca volvulus Cathepsin L homolog 0.0027 0.041 0.029
Echinococcus granulosus tm gpcr rhodopsin 0.0034 0.0649 0.0649
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0083 0.0083
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0755 0.0952
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0755 0.0952
Onchocerca volvulus 0.0034 0.0649 0.0603
Echinococcus granulosus biogenic amine 5HT receptor 0.0034 0.0649 0.0649
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0667 0.085
Schistosoma mansoni hypothetical protein 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0667 0.0667
Echinococcus granulosus chromatin regulatory protein sir2 0.0108 0.3336 0.3336
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0029 0.0485 0.0485
Entamoeba histolytica cysteine protease, putative 0.0018 0.0083 0.0249
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0108 0.3336 0.3336
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0034 0.0649 0.0649
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0034 0.0649 0.0649
Onchocerca volvulus 0.0034 0.0649 0.0603
Brugia malayi hypothetical protein 0.0034 0.0649 0.0649
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0034 0.0649 0.0649
Brugia malayi follicle stimulating hormone receptor 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Brugia malayi beta-lactamase family protein 0.0037 0.0755 0.0755
Schistosoma mansoni tar DNA-binding protein 0.02 0.6632 0.6632
Echinococcus multilocularis g protein coupled receptor 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Schistosoma mansoni cathepsin F (C01 family) 0.0027 0.041 0.041
Echinococcus granulosus neuropeptide s receptor 0.0034 0.0649 0.0649
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0034 0.0649 0.0603
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0649 0.0649
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0099 0.2996 0.8983
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0755 0.0961
Echinococcus granulosus tm gpcr rhodopsin 0.0034 0.0649 0.0649
Schistosoma mansoni tar DNA-binding protein 0.02 0.6632 0.6632
Echinococcus granulosus somatostatin receptor 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0034 0.0649 0.0649
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0293 1 1
Schistosoma mansoni hypothetical protein 0.0034 0.0649 0.0649
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.041 0.0521
Brugia malayi Papain family cysteine protease containing protein 0.0027 0.041 0.041
Onchocerca volvulus 0.0034 0.0649 0.0603
Schistosoma mansoni hypothetical protein 0.0073 0.2072 0.2072
Echinococcus granulosus tm gpcr rhodopsin 0.0034 0.0649 0.0649
Echinococcus granulosus orexin receptor type 2 0.0034 0.0649 0.0649
Schistosoma mansoni neuropeptide f receptor 76f 0.0034 0.0649 0.0649
Loa Loa (eye worm) neuropeptide F receptor 0.0034 0.0649 0.0649
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.041 0.0521
Echinococcus granulosus cysteine protease 0.0018 0.0083 0.0083
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.0649 0.0649
Schistosoma mansoni amine GPCR 0.0034 0.0649 0.0649
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0034 0.0649 0.0649
Echinococcus granulosus serotonin receptor 0.0034 0.0649 0.0649
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0755 0.0755
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.041 0.0521
Giardia lamblia Hypothetical protein 0.0108 0.3336 1
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0099 0.2996 0.2996
Onchocerca volvulus 0.0034 0.0649 0.0603
Brugia malayi putative neuropeptide receptor 0.0034 0.0649 0.0649
Onchocerca volvulus 0.0034 0.0649 0.0603
Loa Loa (eye worm) hypothetical protein 0.0037 0.0755 0.0755
Brugia malayi Melatonin receptor type 1A 0.0034 0.0649 0.0649
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0667 0.085
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.008 0.2302 0.69
Brugia malayi Cathepsin L-like precursor 0.0027 0.041 0.041
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0755 0.0755
Onchocerca volvulus Cathepsin F homolog 0.0027 0.041 0.029
Brugia malayi RNA recognition motif domain containing protein 0.02 0.6632 0.6632
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0034 0.0649 0.0649
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.008 0.2302 0.69
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Echinococcus multilocularis dro:myosuppressin receptor 0.0034 0.0649 0.0649
Brugia malayi Cathepsin L-like precursor 0.0027 0.041 0.041
Brugia malayi ORL1-like opioid receptor 0.0034 0.0649 0.0649
Mycobacterium tuberculosis Conserved protein 0.0037 0.0755 0.0952
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.041 0.0521
Echinococcus granulosus cathepsin l1 0.0021 0.0187 0.0187
Trypanosoma cruzi cysteine proteinase, putative 0.0018 0.0083 0.0083
Brugia malayi transcriptional regulator, Sir2 family protein 0.0108 0.3336 0.3336
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0034 0.0649 0.0649
Trypanosoma brucei Silent information regulator 2 related protein 1 0.0108 0.3336 1
Echinococcus granulosus fmrfamide receptor 0.0034 0.0649 0.0649
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.0649 0.0649
Giardia lamblia Cathepsin B precursor 0.0099 0.2996 0.8983
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Echinococcus multilocularis neuropeptide Y receptor 0.0034 0.0649 0.0649
Echinococcus granulosus cathepsin b 0.0293 1 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Onchocerca volvulus 0.0029 0.0485 0.0389
Echinococcus granulosus tar DNA binding protein 0.02 0.6632 0.6632
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0034 0.0649 0.0649
Loa Loa (eye worm) TAR-binding protein 0.02 0.6632 0.6632
Trypanosoma cruzi Silent information regulator 2 related protein 1 0.0108 0.3336 0.3336
Echinococcus granulosus cathepsin l1 0.0027 0.041 0.041
Leishmania major cathepsin L-like protease 0.008 0.2302 0.69
Toxoplasma gondii NAC domain-containing protein 0.0035 0.0667 0.2227
Schistosoma mansoni growth hormone secretagogue receptor 0.0034 0.0649 0.0649
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0649 0.0649
Schistosoma mansoni opsin-like receptor 0.0034 0.0649 0.0649
Loa Loa (eye worm) G-protein coupled receptor 0.0034 0.0649 0.0649
Echinococcus multilocularis neuropeptide receptor 0.0034 0.0649 0.0649
Brugia malayi AKH receptor 0.0034 0.0649 0.0649
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0649 0.0649
Schistosoma mansoni amine GPCR 0.0034 0.0649 0.0649
Echinococcus granulosus neuropeptides capa receptor 0.0034 0.0649 0.0649
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.008 0.2302 0.69
Brugia malayi hypothetical protein 0.0034 0.0649 0.0649
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0018 0.0083 0.0083
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0034 0.0649 0.0649
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.041 0.0521
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.0649 0.0649
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0649 0.0649
Plasmodium falciparum cysteine proteinase falcipain 1 0.0018 0.0083 0.1246
Echinococcus multilocularis neuropeptide receptor A26 0.0034 0.0649 0.0649
Schistosoma mansoni adenoreceptor 0.0034 0.0649 0.0649
Echinococcus multilocularis G-protein coupled receptor, putative 0.0034 0.0649 0.0649
Entamoeba histolytica cysteine proteinase 1, putative 0.0018 0.0083 0.0249
Entamoeba histolytica cysteine protease, putative 0.0018 0.0083 0.0249
Loa Loa (eye worm) hypothetical protein 0.0107 0.3298 0.3298
Echinococcus multilocularis g protein coupled receptor 0.0034 0.0649 0.0649
Onchocerca volvulus 0.0034 0.0649 0.0603
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0107 0.3298 0.3298
Schistosoma mansoni hypothetical protein 0.0034 0.0649 0.0649
Schistosoma mansoni amine GPCR 0.0034 0.0649 0.0649
Brugia malayi G protein-coupled receptor 0.0034 0.0649 0.0649
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0649 0.0649
Echinococcus granulosus dro:myosuppressin receptor 0.0034 0.0649 0.0649
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0108 0.3336 1
Schistosoma mansoni neuropeptide receptor 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0755 0.5
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.041 0.0521
Trypanosoma cruzi cysteine protease, putative 0.0018 0.0083 0.0083
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0649 0.0649
Echinococcus multilocularis cathepsin b 0.0293 1 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0755 0.0755
Leishmania major cathepsin L-like protease 0.0027 0.041 0.1228
Brugia malayi hypothetical protein 0.0034 0.0649 0.0649
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0649 0.0649
Echinococcus granulosus NAD dependent deacetylase sirtuin 3 0.0108 0.3336 0.3336
Entamoeba histolytica cysteine proteinase, putative 0.0027 0.041 0.1228
Leishmania major basic transcription factor 3a, putative 0.0035 0.0667 0.2001
Brugia malayi hypothetical protein 0.0034 0.0649 0.0649
Echinococcus multilocularis tar DNA binding protein 0.02 0.6632 0.6632
Toxoplasma gondii cathepsin B 0.0099 0.2996 1
Echinococcus multilocularis neuropeptide Y receptor 0.0034 0.0649 0.0649
Schistosoma mansoni cathepsin F (C01 family) 0.0027 0.041 0.041
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0034 0.0649 0.0649
Schistosoma mansoni tar DNA-binding protein 0.02 0.6632 0.6632
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0083 0.0083
Leishmania major cathepsin L-like protease 0.0027 0.041 0.1228
Echinococcus multilocularis fmrfamide receptor 0.0034 0.0649 0.0649
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0034 0.0649 0.0649
Brugia malayi Dopamine receptor 0.0034 0.0649 0.0649
Schistosoma mansoni hypothetical protein 0.017 0.5548 0.5548
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0083 0.0249
Entamoeba histolytica cysteine protease, putative 0.0018 0.0083 0.0249
Echinococcus multilocularis serotonin receptor 0.0034 0.0649 0.0649
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0021 0.0187 0.0238
Trypanosoma cruzi cysteine peptidase, putative 0.008 0.2302 0.2302
Echinococcus granulosus 7TM GPCR rhodopsin 0.0034 0.0649 0.0649
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0034 0.0649 0.0649
Brugia malayi Pre-SET motif family protein 0.0205 0.6832 0.6832
Entamoeba histolytica cysteine protease, putative 0.0018 0.0083 0.0249
Echinococcus multilocularis transcription factor btf3 0.0035 0.0667 0.0667
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0649 0.0649
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0755 1
Brugia malayi Serotonin receptor 0.0034 0.0649 0.0649
Entamoeba histolytica cysteine protease, putative 0.0018 0.0083 0.0249
Entamoeba histolytica cysteine proteinase 2 0.0018 0.0083 0.0249
Loa Loa (eye worm) hypothetical protein 0.0037 0.0755 0.0755
Echinococcus multilocularis allatostatin A receptor 0.0034 0.0649 0.0649
Onchocerca volvulus 0.0034 0.0649 0.0603
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0074 0.2079 0.2079
Echinococcus multilocularis neuropeptide receptor 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Schistosoma mansoni neuropeptide receptor 0.0034 0.0649 0.0649
Echinococcus granulosus biogenic amine 5HT receptor 0.0034 0.0649 0.0649
Brugia malayi cathepsin L-like precursor 0.0021 0.0187 0.0187
Echinococcus multilocularis orexin receptor type 2 0.0034 0.0649 0.0649
Schistosoma mansoni neuropeptide receptor 0.0034 0.0649 0.0649
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0446 0.0446
Brugia malayi hypothetical protein 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Loa Loa (eye worm) fibroinase 0.0027 0.041 0.041
Onchocerca volvulus 0.0027 0.041 0.029
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0649 0.0649
Echinococcus granulosus neuropeptides capa receptor 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Trypanosoma brucei transcription factor BTF3, putative 0.0035 0.0667 0.2001
Echinococcus multilocularis chromatin regulatory protein sir2 0.0108 0.3336 0.3336
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Schistosoma mansoni hypothetical protein 0.0034 0.0649 0.0649
Echinococcus granulosus 7tm_1 domain containing protein 0.0034 0.0649 0.0649
Schistosoma mansoni biogenic amine receptor 0.0034 0.0649 0.0649
Onchocerca volvulus 0.0034 0.0649 0.0603
Brugia malayi hypothetical protein 0.0034 0.0649 0.0649
Plasmodium vivax vivapain-2 0.0027 0.041 0.5425
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.008 0.2302 0.69
Echinococcus multilocularis fmrfamide receptor 0.0034 0.0649 0.0649
Brugia malayi Dopamine receptor protein 2 0.0034 0.0649 0.0649
Echinococcus granulosus allatostatin A receptor 0.0034 0.0649 0.0649
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0667 0.085
Schistosoma mansoni amine GPCR 0.0034 0.0649 0.0649
Echinococcus granulosus tachykinin peptides receptor 99D 0.0034 0.0649 0.0649
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.041 0.0521
Loa Loa (eye worm) hypothetical protein 0.0021 0.0187 0.0187
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0034 0.0649 0.0649
Brugia malayi Cathepsin L-like cysteine proteinase 0.0021 0.0187 0.0187
Echinococcus granulosus cathepsin L cysteine proteinase 0.0027 0.041 0.041
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0034 0.0649 0.0649
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0034 0.0649 0.0649
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0649 0.0649
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0755 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0034 0.0649 0.0649
Brugia malayi Cathepsin L-like precursor 0.0027 0.041 0.041
Loa Loa (eye worm) hypothetical protein 0.0027 0.041 0.041
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0021 0.0187 0.0187
Onchocerca volvulus 0.0037 0.0755 0.0741
Onchocerca volvulus 0.0034 0.0649 0.0603
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0034 0.0649 0.0649
Brugia malayi neuropeptide F receptor 0.0034 0.0649 0.0649
Mycobacterium ulcerans lipase LipD 0.0037 0.0755 1
Leishmania major cysteine peptidase A (CPA) 0.0027 0.041 0.1228
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0037 0.0755 0.0755
Entamoeba histolytica cysteine protease, putative 0.0018 0.0083 0.0249
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0034 0.0649 0.0649
Echinococcus multilocularis cathepsin L cysteine protease 0.0027 0.041 0.041
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0027 0.041 0.6137
Schistosoma mansoni chromatin regulatory protein sir2 0.0108 0.3336 0.3336
Mycobacterium tuberculosis Conserved protein 0.0037 0.0755 0.0952
Brugia malayi Cathepsin L-like precursor 0.0021 0.0187 0.0187
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0649 0.0649
Entamoeba histolytica cysteine protease, putative 0.0018 0.0083 0.0249
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0034 0.0649 0.0649
Echinococcus granulosus g-protein coupled receptor 0.0034 0.0649 0.0649
Brugia malayi latrophilin 2 splice variant baaae 0.0073 0.2072 0.2072
Brugia malayi Pre-SET motif family protein 0.0029 0.0485 0.0485
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0293 1 1
Brugia malayi Tachykinin-like peptides receptor 99D 0.0034 0.0649 0.0649
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0034 0.0649 0.0649
Schistosoma mansoni chromatin regulatory protein sir2 0.0108 0.3336 0.3336
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0027 0.041 0.041
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0034 0.0649 0.0649
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0027 0.041 0.0521
Onchocerca volvulus Cathepsin L homolog 0.0027 0.041 0.029
Echinococcus granulosus cathepsin L 0.0018 0.0083 0.0083
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.008 0.2302 0.69
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.02 0.6632 0.6632
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0083 0.0106
Toxoplasma gondii ABC1 family protein 0.0037 0.0755 0.252
Onchocerca volvulus 0.0034 0.0649 0.0603
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0755 0.0755
Echinococcus granulosus neuropeptide receptor 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0037 0.0755 0.0755
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.041 0.0521
Entamoeba histolytica cysteine protease, putative 0.0018 0.0083 0.0249
Schistosoma mansoni biogenic amine receptor 0.0034 0.0649 0.0649
Schistosoma mansoni hypothetical protein 0.0034 0.0649 0.0649
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0205 0.6832 0.6832
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Mycobacterium ulcerans beta-lactamase 0.0037 0.0755 1
Trypanosoma brucei cysteine peptidase C (CPC) 0.0099 0.2996 0.8983
Onchocerca volvulus 0.0034 0.0649 0.0603
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.041 0.0521
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0083 0.0106
Entamoeba histolytica transcription factor BTF3, putative 0.0035 0.0667 0.2001
Plasmodium vivax basic transcription factor 3b, putative 0.0035 0.0667 0.8839
Brugia malayi Dopamine receptor protein 1 0.0034 0.0649 0.0649
Echinococcus granulosus alpha 1A adrenergic receptor 0.0034 0.0649 0.0649
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0018 0.0083 0.0249
Echinococcus granulosus g protein coupled receptor 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0755 0.0952
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Loa Loa (eye worm) transcriptional regulator 0.0108 0.3336 0.3336
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0649 0.0649
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.008 0.2302 0.69
Toxoplasma gondii cathepsin CPL 0.0027 0.041 0.1367
Brugia malayi Cathepsin L-like precursor 0.0027 0.041 0.041
Onchocerca volvulus 0.0034 0.0649 0.0603
Giardia lamblia Cathepsin B precursor 0.0099 0.2996 0.8983
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0099 0.2996 0.3814
Echinococcus multilocularis sex peptide receptor 0.0034 0.0649 0.0649
Echinococcus granulosus cathepsin l cysteine peptidase 0.0027 0.041 0.041
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0649 0.0649
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0649 0.0649
Plasmodium vivax vivapain-2 0.0027 0.041 0.5425
Brugia malayi beta-NAC-like protein 0.0035 0.0667 0.0667
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Echinococcus granulosus G protein coupled receptor 139 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Mycobacterium ulcerans hypothetical protein 0.0037 0.0755 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0027 0.041 0.0521
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0755 0.0755
Schistosoma mansoni tar DNA-binding protein 0.02 0.6632 0.6632
Schistosoma mansoni tar DNA-binding protein 0.02 0.6632 0.6632
Schistosoma mansoni biogenic amine (5HT) receptor 0.0034 0.0649 0.0649
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Trypanosoma cruzi cysteine peptidase, putative 0.0027 0.041 0.041
Brugia malayi hypothetical protein 0.0034 0.0649 0.0649
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.008 0.2302 0.69
Echinococcus multilocularis cysteine protease 0.0027 0.041 0.041
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0034 0.0649 0.0649
Echinococcus granulosus neuropeptide receptor A26 0.0034 0.0649 0.0649
Entamoeba histolytica cysteine protease, putative 0.0018 0.0083 0.0249
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0073 0.2072 0.2072
Entamoeba histolytica cysteine proteinase, putative 0.0027 0.041 0.1228
Onchocerca volvulus 0.0027 0.041 0.029
Echinococcus granulosus GPCR family 2 0.0034 0.0649 0.0649
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.041 0.0521
Mycobacterium tuberculosis Conserved protein 0.0037 0.0755 0.0952
Echinococcus granulosus hypothetical protein 0.0034 0.0649 0.0649
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.0108 0.3336 1
Trichomonas vaginalis set domain proteins, putative 0.0234 0.7855 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Loa Loa (eye worm) RNA binding protein 0.02 0.6632 0.6632
Loa Loa (eye worm) hypothetical protein 0.0021 0.0187 0.0187
Onchocerca volvulus 0.0027 0.041 0.029
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0083 0.0249
Loa Loa (eye worm) hypothetical protein 0.0185 0.6103 0.6103
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0108 0.3336 0.4246
Onchocerca volvulus 0.0037 0.0755 0.0741
Schistosoma mansoni opsin-like receptor 0.0034 0.0649 0.0649
Plasmodium falciparum basic transcription factor 3b, putative 0.0035 0.0667 1
Schistosoma mansoni histamine h1 receptor 0.0034 0.0649 0.0649
Echinococcus granulosus g protein coupled receptor 0.0034 0.0649 0.0649
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.041 0.0521
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0027 0.041 0.6137
Giardia lamblia Cathepsin B precursor 0.0099 0.2996 0.8983
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0755 0.0961
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0185 0.6103 0.7715
Entamoeba histolytica hypothetical protein 0.0035 0.0667 0.2001
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0649 0.0649
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0755 0.0961
Schistosoma mansoni hypothetical protein 0.0034 0.0649 0.0649
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.008 0.2302 0.69
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0034 0.0649 0.0649
Leishmania major silent information regulator 2, putative 0.0108 0.3336 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.041 0.0521
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0755 0.0755
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0037 0.0755 0.0755
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0755 0.0961
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.008 0.2302 0.69
Echinococcus granulosus neuropeptide FF receptor 2 0.0034 0.0649 0.0649
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.0649 0.0649
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0034 0.0649 0.0649
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0755 0.0952
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0485 0.0485
Entamoeba histolytica cysteine proteinase, putative 0.0021 0.0187 0.0561
Echinococcus granulosus sex peptide receptor 0.0034 0.0649 0.0649
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0083 0.0083
Leishmania major cathepsin L-like protease 0.008 0.2302 0.69
Brugia malayi Cathepsin L-like precursor 0.0021 0.0187 0.0187
Entamoeba histolytica cysteine protease, putative 0.0018 0.0083 0.0249
Loa Loa (eye worm) cathepsin B 0.0099 0.2996 0.2996
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0034 0.0649 0.0649
Schistosoma mansoni myosin xvIII 0.0034 0.0649 0.0649
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0755 0.0755
Onchocerca volvulus 0.0027 0.041 0.029
Echinococcus multilocularis neuropeptide FF receptor 2 0.0034 0.0649 0.0649
Onchocerca volvulus 0.0034 0.0649 0.0603
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0755 0.0952
Trypanosoma cruzi major cysteine proteinase, putative 0.0065 0.1753 0.1753
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0034 0.0649 0.0649
Echinococcus multilocularis GPCR, family 2 0.0034 0.0649 0.0649
Echinococcus multilocularis neuropeptides capa receptor 0.0034 0.0649 0.0649
Brugia malayi hypothetical protein 0.0034 0.0649 0.0649
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.041 0.0521
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0485 0.0485
Loa Loa (eye worm) hypothetical protein 0.0037 0.0755 0.0755
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0034 0.0649 0.0649
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0083 0.0083
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0485 0.0485
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0034 0.0649 0.0649
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.041 0.0521
Trypanosoma cruzi cysteine peptidase, putative 0.008 0.2302 0.2302
Loa Loa (eye worm) cysteine protease 0.0027 0.041 0.041
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0755 0.0961
Loa Loa (eye worm) TYRA-2 protein 0.0034 0.0649 0.0649
Brugia malayi GnHR receptor homolog 0.0034 0.0649 0.0649
Brugia malayi beta-lactamase 0.0037 0.0755 0.0755
Brugia malayi putative neuropeptide receptor NPR1 0.0034 0.0649 0.0649
Onchocerca volvulus 0.0027 0.041 0.029
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.041 0.0521
Schistosoma mansoni hypothetical protein 0.0034 0.0649 0.0649
Entamoeba histolytica cysteine protease, putative 0.0018 0.0083 0.0249
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0034 0.0649 0.0649
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0755 0.0755
Echinococcus multilocularis g protein coupled receptor 0.0034 0.0649 0.0649
Schistosoma mansoni neuropeptide F-like receptor 0.0034 0.0649 0.0649
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0027 0.041 0.041
Brugia malayi Latrophilin receptor protein 2 0.0034 0.0649 0.0649
Echinococcus multilocularis cathepsin b 0.0293 1 1
Onchocerca volvulus 0.0027 0.041 0.029
Loa Loa (eye worm) G-protein coupled receptor 0.0034 0.0649 0.0649
Echinococcus multilocularis G protein coupled receptor 139 0.0034 0.0649 0.0649
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0649 0.0649
Leishmania major cathepsin L-like protease 0.0027 0.041 0.1228
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0293 1 1
Brugia malayi hypothetical protein 0.0034 0.0649 0.0649
Loa Loa (eye worm) melatonin receptor type 1A 0.0034 0.0649 0.0649
Schistosoma mansoni hypothetical protein 0.0034 0.0649 0.0649
Brugia malayi N-terminal motif family protein 0.0185 0.6103 0.6103
Schistosoma mansoni amine GPCR 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0649 0.0649
Echinococcus granulosus cathepsin L cysteine protease 0.0018 0.0083 0.0083
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.041 0.0521
Schistosoma mansoni cathepsin F (C01 family) 0.0021 0.0187 0.0187
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0293 1 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Brugia malayi Serotonin receptor 0.0034 0.0649 0.0649
Schistosoma mansoni biogenic amine receptor 0.0034 0.0649 0.0649
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.041 0.0521
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0236 0.7935 1
Schistosoma mansoni opsin-like receptor 0.0034 0.0649 0.0649
Echinococcus multilocularis NAD dependent deacetylase sirtuin 3 0.0108 0.3336 0.3336
Echinococcus multilocularis cathepsin L 0.0018 0.0083 0.0083
Trichomonas vaginalis chromatin regulatory protein sir2, putative 0.0108 0.3336 0.4246
Brugia malayi RE15519p 0.0034 0.0649 0.0649
Echinococcus granulosus rhodopsin orphan GPCR 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Loa Loa (eye worm) ctsf protein 0.0027 0.041 0.041
Plasmodium falciparum cysteine proteinase falcipain 3 0.0027 0.041 0.6137
Echinococcus multilocularis somatostatin receptor 0.0034 0.0649 0.0649
Brugia malayi G-protein coupled receptor 0.0034 0.0649 0.0649
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.041 0.0521
Brugia malayi TAR-binding protein 0.02 0.6632 0.6632
Leishmania major cathepsin L-like protease 0.0027 0.041 0.1228
Brugia malayi beta-lactamase family protein 0.0037 0.0755 0.0755
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Plasmodium vivax SET domain protein, putative 0.0029 0.0485 0.6429
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0034 0.0649 0.0649
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0034 0.0649 0.0649
Schistosoma mansoni neuropeptide receptor 0.0034 0.0649 0.0649
Schistosoma mansoni neuropeptide F-like receptor 0.0034 0.0649 0.0649
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0083 0.0083
Trypanosoma cruzi cruzipain precursor, putative 0.008 0.2302 0.2302
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0018 0.0083 0.0083
Onchocerca volvulus 0.0034 0.0649 0.0603
Loa Loa (eye worm) neuropeptide F receptor 0.0034 0.0649 0.0649
Onchocerca volvulus 0.0034 0.0649 0.0603
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Trypanosoma cruzi transcription factor btf3, putative 0.0035 0.0667 0.0667
Trypanosoma cruzi cysteine peptidase, putative 0.008 0.2302 0.2302
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0021 0.0187 0.0238
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0293 1 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0485 0.0485
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0649 0.0649
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0083 0.0249
Echinococcus multilocularis cathepsin L cysteine protease 0.0027 0.041 0.041
Echinococcus granulosus peptide allatostatin:somatostatin 0.0034 0.0649 0.0649
Schistosoma mansoni alpha-1 adrenergic receptor 0.0034 0.0649 0.0649
Echinococcus granulosus g protein coupled receptor 0.0034 0.0649 0.0649
Leishmania major hypothetical protein, conserved 0.0037 0.0755 0.2264
Echinococcus multilocularis serotonin receptor 0.0034 0.0649 0.0649
Onchocerca volvulus 0.0034 0.0649 0.0603
Echinococcus multilocularis neuropeptide s receptor 0.0034 0.0649 0.0649
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.0649 0.0649
Echinococcus granulosus neuropeptide receptor 0.0034 0.0649 0.0649
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0034 0.0649 0.0649
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0083 0.0249
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0027 0.041 0.041
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0755 0.0952
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0027 0.041 0.0521
Onchocerca volvulus Neuropeptide F receptor homolog 0.0034 0.0649 0.0603
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0034 0.0649 0.0649
Entamoeba histolytica cysteine proteinase, putative 0.0018 0.0083 0.0249
Echinococcus granulosus cathepsin b 0.0293 1 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0485 0.162
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0649 0.0649
Brugia malayi RNA binding protein 0.02 0.6632 0.6632
Brugia malayi Cathepsin L-like precursor 0.0027 0.041 0.041
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.041 0.0521
Brugia malayi Calcitonin receptor-like protein seb-1 0.0107 0.3298 0.3298
Leishmania major cathepsin L-like protease 0.008 0.2302 0.69
Echinococcus granulosus neuropeptide Y receptor 0.0034 0.0649 0.0649
Entamoeba histolytica cysteine protease, putative 0.0018 0.0083 0.0249
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.041 0.0521
Onchocerca volvulus 0.0027 0.041 0.029
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0034 0.0649 0.0649
Echinococcus granulosus geminin 0.017 0.5548 0.5548
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0485 0.0485
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0755 0.2264
Schistosoma mansoni biogenic amine (5HT) receptor 0.0034 0.0649 0.0649
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0027 0.041 0.0521
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0755 1
Echinococcus granulosus neuropeptide Y receptor 0.0034 0.0649 0.0649
Echinococcus multilocularis g-protein coupled receptor 0.0034 0.0649 0.0649
Plasmodium vivax vivapain-1 0.0018 0.0083 0.1101
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Trichomonas vaginalis esterase, putative 0.0037 0.0755 0.0961
Brugia malayi hypothetical protein 0.0034 0.0649 0.0649
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0485 0.0485
Mycobacterium leprae Probable lipase LipE 0.0037 0.0755 0.5
Brugia malayi neuropeptide F receptor 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Loa Loa (eye worm) ICD-1 protein 0.0035 0.0667 0.0667
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0034 0.0649 0.0649
Onchocerca volvulus 0.0234 0.7855 1
Entamoeba histolytica cysteine protease, putative 0.0027 0.041 0.1228
Loa Loa (eye worm) beta-lactamase 0.0037 0.0755 0.0755
Entamoeba histolytica cysteine protease, putative 0.0018 0.0083 0.0249
Leishmania major cathepsin L-like protease 0.0027 0.041 0.1228
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.0485 0.0485
Brugia malayi larval opioid receptor 0.0034 0.0649 0.0649
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0099 0.2996 0.2996
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Onchocerca volvulus 0.0037 0.0755 0.0741
Brugia malayi G-protein coupled receptor 0.0034 0.0649 0.0649
Schistosoma mansoni hypothetical protein 0.017 0.5548 0.5548
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0107 0.3298 0.3298
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0027 0.041 0.041
Echinococcus granulosus transcription factor btf3 0.0035 0.0667 0.0667
Echinococcus multilocularis rhodopsin orphan GPCR 0.0034 0.0649 0.0649
Echinococcus multilocularis geminin 0.017 0.5548 0.5548
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Brugia malayi sulfakinin receptor protein 0.0034 0.0649 0.0649
Loa Loa (eye worm) hypothetical protein 0.0293 1 1
Schistosoma mansoni transcription factor btf3 0.0035 0.0667 0.0667
Loa Loa (eye worm) hypothetical protein 0.0034 0.0649 0.0649
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.008 0.2302 0.69
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0034 0.0649 0.0649
Echinococcus multilocularis neuropeptides capa receptor 0.0034 0.0649 0.0649

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) > 1056 uM The concentration of compound required to cause 50% hemolysis in the absence of complement ChEMBL. No reference
IC50 (functional) > 1056 uM The concentration of compound required to inhibit complement induced hemolysis by 50% ChEMBL. No reference
IC50 (functional) > 1056 uM The concentration of compound required to inhibit complement induced hemolysis by 50% ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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