Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | hypothetical protein, conserved | 0.0013 | 0.5 | 0.5 |
Toxoplasma gondii | macro domain-containing protein | 0.0013 | 0.5 | 0.5 |
Trypanosoma cruzi | Macro domain containing protein, putative | 0.0013 | 0.5 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.5 | 0.5 |
Trichomonas vaginalis | ganglioside induced differentiation associated protein, putative | 0.0013 | 0.5 | 0.5 |
Plasmodium falciparum | Appr-1-p processing domain protein | 0.0013 | 0.5 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.5 | 0.5 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0013 | 0.5 | 0.5 |
Giardia lamblia | Protein LRP16 | 0.0013 | 0.5 | 0.5 |
Trichomonas vaginalis | ganglioside induced differentiation associated protein, putative | 0.0013 | 0.5 | 0.5 |
Echinococcus granulosus | MACRO domain containing protein 2 | 0.0013 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Possible lipoprotein LppD | 0.0013 | 0.5 | 0.5 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0013 | 0.5 | 0.5 |
Plasmodium vivax | hypothetical protein, conserved | 0.0013 | 0.5 | 0.5 |
Mycobacterium ulcerans | lipoprotein LppD | 0.0013 | 0.5 | 0.5 |
Echinococcus multilocularis | MACRO domain containing protein 2 | 0.0013 | 0.5 | 0.5 |
Echinococcus multilocularis | MACRO domain containing protein 2 | 0.0013 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.5 | 0.5 |
Echinococcus granulosus | MACRO domain containing protein 2 | 0.0013 | 0.5 | 0.5 |
Trypanosoma brucei | Macro domain containing protein, putative | 0.0013 | 0.5 | 0.5 |
Trypanosoma cruzi | Macro domain containing protein, putative | 0.0013 | 0.5 | 0.5 |
Trichomonas vaginalis | ganglioside induced differentiation associated protein, putative | 0.0013 | 0.5 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.