Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0029 | 0.095 | 0.086 |
Leishmania major | calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative | 0.0023 | 0.0486 | 0.1763 |
Echinococcus granulosus | calpain A | 0.0023 | 0.0486 | 0.0392 |
Onchocerca volvulus | 0.0029 | 0.095 | 0.4962 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0029 | 0.095 | 0.095 |
Entamoeba histolytica | cysteine protease, putative | 0.0017 | 0.0098 | 0.103 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0055 | 0.2759 | 0.2688 |
Echinococcus granulosus | calpain 7 C02 family | 0.0023 | 0.0486 | 0.0392 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0029 | 0.095 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.095 | 0.3201 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0156 | 1 | 1 |
Schistosoma mansoni | Mername-AA248 (C02 family) | 0.0023 | 0.0486 | 0.0392 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0055 | 0.2759 | 1 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.095 | 0.3442 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.095 | 0.3442 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0023 | 0.0486 | 0.0486 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0029 | 0.095 | 1 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0023 | 0.0486 | 0.0486 |
Leishmania major | cysteine peptidase A (CPA) | 0.0029 | 0.095 | 0.3442 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0044 | 0.2026 | 0.2026 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.095 | 0.3201 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0029 | 0.095 | 0.095 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0369 | 0.0369 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0021 | 0.0369 | 0.1018 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.095 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.095 | 0.3201 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.095 | 0.095 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.095 | 0.3201 |
Brugia malayi | calpain 7 | 0.0023 | 0.0486 | 0.0486 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.095 | 0.3201 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.095 | 0.095 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0023 | 0.0486 | 0.0486 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.095 | 0.3201 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0023 | 0.0486 | 0.0486 |
Leishmania major | calpain, putative,cysteine peptidase, Clan CA, family C2, putative | 0.0023 | 0.0486 | 0.1763 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0029 | 0.095 | 0.095 |
Loa Loa (eye worm) | cysteine protease | 0.0029 | 0.095 | 0.095 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0029 | 0.095 | 0.095 |
Brugia malayi | Cathepsin L-like precursor | 0.0021 | 0.0369 | 0.0369 |
Entamoeba histolytica | cysteine protease, putative | 0.0017 | 0.0098 | 0.103 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.006 | 0.3157 | 0.3089 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.095 | 0.3442 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.095 | 0.3442 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0023 | 0.0486 | 0.0486 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0029 | 0.095 | 0.095 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.095 | 0.3201 |
Entamoeba histolytica | cysteine protease, putative | 0.0017 | 0.0098 | 0.103 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0029 | 0.095 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0021 | 0.0369 | 0.0369 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.095 | 0.095 |
Trypanosoma cruzi | cysteine protease, putative | 0.0017 | 0.0098 | 0.0098 |
Leishmania major | calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative | 0.0023 | 0.0486 | 0.1763 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.095 | 0.095 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0029 | 0.095 | 0.086 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.095 | 0.3442 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.095 | 0.3442 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0017 | 0.0098 | 0.103 |
Echinococcus granulosus | cathepsin b | 0.0156 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0156 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.095 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.095 | 0.3201 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0029 | 0.095 | 0.086 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.095 | 0.095 |
Echinococcus multilocularis | cysteine protease | 0.0029 | 0.095 | 0.086 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0021 | 0.0369 | 0.3884 |
Echinococcus multilocularis | calpain A | 0.0063 | 0.3351 | 0.3286 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0017 | 0.0098 | 0.0098 |
Plasmodium vivax | vivapain-2 | 0.0029 | 0.095 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0029 | 0.095 | 0.086 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0023 | 0.0486 | 0.0486 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0029 | 0.095 | 1 |
Onchocerca volvulus | 0.0029 | 0.095 | 0.4962 | |
Echinococcus multilocularis | calpain family protein 1, d | 0.0044 | 0.2026 | 0.1947 |
Loa Loa (eye worm) | cathepsin B | 0.0055 | 0.2759 | 0.2759 |
Echinococcus multilocularis | calpain 5 | 0.0023 | 0.0486 | 0.0392 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.095 | 0.095 |
Loa Loa (eye worm) | fibroinase | 0.0029 | 0.095 | 0.095 |
Entamoeba histolytica | cysteine protease, putative | 0.0017 | 0.0098 | 0.103 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0055 | 0.2759 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0021 | 0.0369 | 0.0274 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0029 | 0.095 | 0.095 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.2026 | 0.2026 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0029 | 0.095 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.095 | 0.3201 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0023 | 0.0486 | 0.0486 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.095 | 0.3442 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.095 | 0.3201 |
Plasmodium vivax | calpain, putative | 0.0023 | 0.0486 | 0.456 |
Echinococcus granulosus | calpain | 0.0023 | 0.0486 | 0.0392 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.095 | 0.3442 |
Brugia malayi | calpain family protein 1 | 0.006 | 0.3157 | 0.3157 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.095 | 0.3201 |
Echinococcus granulosus | cathepsin l1 | 0.0021 | 0.0369 | 0.0274 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.095 | 0.3201 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0017 | 0.0098 | 0.103 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0017 | 0.0098 | 0.0355 |
Loa Loa (eye worm) | hypothetical protein | 0.0156 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.095 | 0.3442 |
Trypanosoma brucei | antigen, putative | 0.0023 | 0.0486 | 0.1763 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.095 | 0.3201 |
Schistosoma mansoni | calpain-7 (C02 family) | 0.0023 | 0.0486 | 0.0392 |
Trypanosoma brucei | calpain-like cysteine peptidase, putative | 0.0023 | 0.0486 | 0.1763 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0156 | 1 | 1 |
Loa Loa (eye worm) | calpain | 0.0023 | 0.0486 | 0.0486 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0029 | 0.095 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.095 | 0.3201 |
Echinococcus multilocularis | family C2 unassigned peptidase (C02 family) | 0.0063 | 0.3351 | 0.3286 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0017 | 0.0098 | 0.103 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0156 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.095 | 0.3442 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0029 | 0.095 | 0.086 |
Entamoeba histolytica | cysteine protease, putative | 0.0017 | 0.0098 | 0.103 |
Echinococcus multilocularis | cathepsin b | 0.0156 | 1 | 1 |
Schistosoma mansoni | calpain (C02 family) | 0.0023 | 0.0486 | 0.0392 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.095 | 0.3201 |
Toxoplasma gondii | cathepsin B | 0.0055 | 0.2759 | 1 |
Onchocerca volvulus | 0.0029 | 0.095 | 0.4962 | |
Entamoeba histolytica | cysteine protease, putative | 0.0017 | 0.0098 | 0.103 |
Schistosoma mansoni | calpain-7 (C02 family) | 0.0023 | 0.0486 | 0.0392 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.095 | 0.3442 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C2, putative | 0.0023 | 0.0486 | 0.1763 |
Entamoeba histolytica | cysteine protease, putative | 0.0017 | 0.0098 | 0.103 |
Onchocerca volvulus | Cathepsin L homolog | 0.0029 | 0.095 | 0.4962 |
Schistosoma mansoni | calpain C (C02 family) | 0.0023 | 0.0486 | 0.0392 |
Echinococcus granulosus | calpain 5 | 0.0023 | 0.0486 | 0.0392 |
Plasmodium vivax | vivapain-2 | 0.0029 | 0.095 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0017 | 0.0098 | 0.0098 |
Onchocerca volvulus | Cathepsin L homolog | 0.0029 | 0.095 | 0.4962 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.095 | 0.3201 |
Echinococcus granulosus | family C2 unassigned peptidase C02 family | 0.0063 | 0.3351 | 0.3286 |
Onchocerca volvulus | 0.0029 | 0.095 | 0.4962 | |
Onchocerca volvulus | 0.0029 | 0.095 | 0.4962 | |
Onchocerca volvulus | 0.0038 | 0.1539 | 1 | |
Echinococcus multilocularis | calpain | 0.0023 | 0.0486 | 0.0392 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0029 | 0.095 | 0.095 |
Echinococcus granulosus | cathepsin b | 0.0156 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.095 | 0.3442 |
Entamoeba histolytica | cysteine protease, putative | 0.0029 | 0.095 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0017 | 0.0098 | 0.0355 |
Onchocerca volvulus | 0.0029 | 0.095 | 0.4962 | |
Echinococcus granulosus | cathepsin l1 | 0.0029 | 0.095 | 0.086 |
Brugia malayi | Cathepsin L-like precursor | 0.0021 | 0.0369 | 0.0369 |
Trypanosoma brucei | calpain-like protein, putative | 0.0023 | 0.0486 | 0.1763 |
Echinococcus multilocularis | cysteine protease | 0.0029 | 0.095 | 0.086 |
Brugia malayi | calpain family protein 1 | 0.006 | 0.3157 | 0.3157 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.095 | 0.3442 |
Onchocerca volvulus | Cathepsin F homolog | 0.0029 | 0.095 | 0.4962 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0055 | 0.2759 | 1 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.095 | 0.3442 |
Entamoeba histolytica | cysteine protease, putative | 0.0017 | 0.0098 | 0.103 |
Echinococcus multilocularis | calpain 7 (C02 family) | 0.0023 | 0.0486 | 0.0392 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0029 | 0.095 | 0.3201 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0017 | 0.0098 | 0.0098 |
Loa Loa (eye worm) | calpain family protein 1 | 0.006 | 0.3157 | 0.3157 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.3157 | 0.3157 |
Giardia lamblia | Cathepsin B precursor | 0.0055 | 0.2759 | 0.5 |
Trypanosoma brucei | calpain-like protein, putative | 0.0023 | 0.0486 | 0.1763 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0021 | 0.0369 | 0.1018 |
Entamoeba histolytica | cysteine protease, putative | 0.0017 | 0.0098 | 0.103 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0017 | 0.0098 | 0.103 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0063 | 0.3351 | 0.3286 |
Trypanosoma cruzi | cysteine peptidase, Clan CA, family C2, putative | 0.0023 | 0.0486 | 0.0486 |
Entamoeba histolytica | cysteine protease, putative | 0.0017 | 0.0098 | 0.103 |
Entamoeba histolytica | cysteine protease, putative | 0.0017 | 0.0098 | 0.103 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.2671 | 0.2671 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0017 | 0.0098 | 0.0098 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.095 | 0.3201 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.095 | 0.3442 |
Echinococcus granulosus | calpain A | 0.0063 | 0.3351 | 0.3286 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0063 | 0.3351 | 0.3286 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0029 | 0.095 | 0.086 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.095 | 0.3442 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0369 | 0.0369 |
Entamoeba histolytica | cysteine protease, putative | 0.0017 | 0.0098 | 0.103 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.095 | 0.3442 |
Trypanosoma brucei | calpain-like protein, putative | 0.0023 | 0.0486 | 0.1763 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0021 | 0.0369 | 0.0369 |
Echinococcus multilocularis | hypothetical protein | 0.0023 | 0.0486 | 0.0392 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0055 | 0.2759 | 0.2759 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.095 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.095 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.095 | 0.095 |
Entamoeba histolytica | cysteine protease, putative | 0.0017 | 0.0098 | 0.103 |
Onchocerca volvulus | 0.0029 | 0.095 | 0.4962 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0017 | 0.0098 | 0.103 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0017 | 0.0098 | 0.0098 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0017 | 0.0098 | 0.103 |
Echinococcus multilocularis | cathepsin b | 0.0156 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.095 | 0.3201 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0029 | 0.095 | 1 |
Trypanosoma cruzi | calpain cysteine peptidase, putative | 0.0023 | 0.0486 | 0.0486 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0369 | 0.0369 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0029 | 0.095 | 0.095 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0156 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0055 | 0.2759 | 0.5 |
Trypanosoma cruzi | calpain-like cysteine peptidase, putative | 0.0023 | 0.0486 | 0.0486 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0017 | 0.0098 | 0.0098 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.095 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1539 | 0.1539 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.095 | 0.3442 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.095 | 0.3442 |
Giardia lamblia | Cathepsin B precursor | 0.0055 | 0.2759 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0029 | 0.095 | 0.3201 |
Brugia malayi | cathepsin L-like precursor | 0.0021 | 0.0369 | 0.0369 |
Trypanosoma brucei | calpain-like protein, putative | 0.0023 | 0.0486 | 0.1763 |
Loa Loa (eye worm) | ctsf protein | 0.0029 | 0.095 | 0.095 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.